Добірка наукової літератури з теми "Interleukin-12"
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Статті в журналах з теми "Interleukin-12"
Leonard, Patricia, and Sanjiv Sur. "Interleukin-12." BioDrugs 17, no. 1 (2003): 1–7. http://dx.doi.org/10.2165/00063030-200317010-00001.
Повний текст джерела&NA;. "Interleukin-12." Inpharma Weekly &NA;, no. 1124 (February 1998): 7. http://dx.doi.org/10.2165/00128413-199811240-00013.
Повний текст джерелаTrinchieri, Giorgio. "Interleukin-12." Clinical Immunotherapeutics 3, no. 4 (April 1995): 262–70. http://dx.doi.org/10.1007/bf03259278.
Повний текст джерелаClinton, Steven K., Eduardo Canto, and Michael A. O'Donnell. "INTERLEUKIN-12." Urologic Clinics of North America 27, no. 1 (February 2000): 147–55. http://dx.doi.org/10.1016/s0094-0143(05)70242-1.
Повний текст джерелаWeiner, David. "Plasmid Interleukin 12." AIDS 14, no. 12 (August 2000): 1759–60. http://dx.doi.org/10.1097/00002030-200008180-00010.
Повний текст джерелаLeng, S. X., and J. A. Elias. "Interleukin-11 inhibits macrophage interleukin-12 production." Journal of Immunology 159, no. 5 (September 1, 1997): 2161–68. http://dx.doi.org/10.4049/jimmunol.159.5.2161.
Повний текст джерелаFox, Robert J., and Abdolmohamad M. Rostami. "Anti???Interleukin-12 Antibody." BioDrugs 13, no. 4 (April 2000): 233–41. http://dx.doi.org/10.2165/00063030-200013040-00002.
Повний текст джерела&NA;. "Interleukin-12 trial halted." Reactions Weekly &NA;, no. 556 (June 1995): 2. http://dx.doi.org/10.2165/00128415-199505560-00003.
Повний текст джерела&NA;. "Interleukin-12 studies continue." Reactions Weekly &NA;, no. 558 (July 1995): 2. http://dx.doi.org/10.2165/00128415-199505580-00003.
Повний текст джерела&NA;. "Interleukin-12 trial halted." Inpharma Weekly &NA;, no. 992 (June 1995): 21. http://dx.doi.org/10.2165/00128413-199509920-00047.
Повний текст джерелаДисертації з теми "Interleukin-12"
Balu, Sucharitha. "Cloning and characterisation of chicken interleukin-12 and the interleukin-12 receptor." Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419213.
Повний текст джерелаSwinburne, Sarah Jane. "A study of the molecular and biological characteristics of ovine interleukin-12." Title page, contents and summary only, 2000. http://web4.library.adelaide.edu.au/theses/09PH/09phs9777.pdf.
Повний текст джерелаWerner, Christoph. "Von Interleukin-12 zur p40-Zytokinfamilie Interleukin-12-unabhängige Wirkungen von p40-Zytokinen in der Infekt- und Tumorabwehr /." [S.l.] : [s.n.], 2003. http://dol.uni-leipzig.de/pub/2003-34.
Повний текст джерелаWerner, Christoph. "Von Interleukin-12 zur p40-Zytokinfamilie: Interleukin-12-unabhängige Wirkungen von p40-Zytokinen in der Infekt- und Tumorabwehr." Doctoral thesis, Universitätsbibliothek Leipzig, 2004. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-37550.
Повний текст джерелаInterleukin-12 (IL-12) is a key cytokine in the development of a protective cellular Th1 immune response. It consists of a p40 and a p35 subunit. Following stimulation with IL-12, NK and T cells produce large amounts of IFN-gamma resulting in a type 1 immune response. The p40 subunit of IL-12 is also part of other biologically active proteins such as monomeric or homodimeric p40 or the heterodimeric IL-23 (in combination with a p19 subunit). While in this study the homodimeric p40 appears to antagonize IL-12, IL-23 was demonstrated to have agonistic effects. The aim of this study was to investigate p40-dependent effects which can be observed independently of IL-12, i.e. potential effects mediated by IL-23. For the experiments mutant mice were used so that IL-12 dependent mechanisms could not play a role but only p40-dependent proteins excluding IL-12. In a Salmonella Enteritidis infection model p35-gene deleted (p35-/-) and p40-/- mice were used. As the expression of p40 is induced by bacterial antigen, differences between the strains were caused by the p40 protein. During the infection p40 proteins induced IFN-gamma production thus improving the killing of intracellular pathogens. This resulted in a better control of the systemic infection and longer survival periods of the p35-/- mice as compared to p40-/- mice. For the experiments in the tumor model using the Lewis-Lung carcinoma and the Melanoma B16 as tumors, p35/40-/- mice which are unable to produce any p40 proteins, received gene therapy with DNA encoding for p40. This local gene therapy resulted in a reduced tumor growth. Immunohistochemical examination revealed an infiltration of the tumor tissue with macrophages and a reduced neoangiogenesis within the tumor. This effect could not be achieved by local administration of IL-23 or the p40-homodimer as a protein, indicating the existence of an as yet unknown heterodimeric p40 protein. In vitro experiments showed that IL-23 induces IFN-gamma production by splenocytes and this effect can be antagonized by the homodimer. Interestingly, IL-23 is also able to antagonize IL-12 in primary splenocyte cultures. In vitro infection with Salmonella resulted in an p40-dependent IFN-gamma production that could also be antagonized by the homodimer. The protective effects in the infection model might be caused by IL-23, which is supported by the in vitro results. On the other hand, in the tumor model IL-23 does not seem to be the player and it must be concluded that the protective effects are caused by an other as yet unknown p40-dependent protein p40-x
Walter, Claudia. "Bestimmung der Zytokine Interleukin-1ra, Interleukin-6, Interleukin-10 und Interleukin-12 im Vaginalsekret bei Frauen mit Bakterieller Vaginose." Diss., lmu, 2004. http://nbn-resolving.de/urn:nbn:de:bvb:19-28461.
Повний текст джерелаChakir, Habiba. "Role of interleukin-12 and interleukin-18 in murine immune cell regulation." Thesis, University of Ottawa (Canada), 2003. http://hdl.handle.net/10393/28980.
Повний текст джерелаRempel, Julia D. "Interleukin-12 and interleukin-10 regulation of antibody responses upon protein antigen immunization." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ41623.pdf.
Повний текст джерелаAthie, Morales Veronica. "Interleukin 12 signalling pathways in human T lymphocytes." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249566.
Повний текст джерелаSchardt, Victor. "Vergleichende Untersuchungen zur Hefepilzbesiedelung von Mundhöhle und Vagina und Bestimmung von Interleukin-4, Interleukin-10 und Interleukin-12." Diss., lmu, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-155152.
Повний текст джерелаNaseer, Tanveer 1971. "In vivo expression of interleukin-12 and interleukin-13 in the pathogenesis of asthma." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23925.
Повний текст джерелаКниги з теми "Interleukin-12"
Lasek, Witold, and Radoslaw Zagozdzon. Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-46906-5.
Повний текст джерелаIl-12 (Chemical Immunology). S. Karger AG (Switzerland), 1997.
Знайти повний текст джерелаInterleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology. Springer International Publishing AG, 2016.
Знайти повний текст джерелаLasek, Witold, Radoslaw Zagozdzon, and Marek Jakóbisiak. Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology. Springer, 2016.
Знайти повний текст джерелаInterleukin 12: Cellular and molecular immunology of an important regulatory cytokine. New York, N.Y: New York Academy of Sciences, 1996.
Знайти повний текст джерелаNew York Academy of Sciences (Corporate Author), Inc. Genetics Institute (Corporate Author), and Michael T. Lotze (Editor), eds. Interleukin 12: Cellular and Molecular Immunology of an Important Regulatory Cytokine (Annals of the New York Academy of Sciences, V. 795). New York Academy of Sciences, 1996.
Знайти повний текст джерела(Editor), Michael T. Lotze, Giorgio Trinchiere (Editor), Maurice Gately (Editor), and Stanley Wolf (Editor), eds. Interleukin 12: Cellular and Molecular Immunology of an Important Regulatory Cytokine (Annals of the New York Academy of Sciences). New York Academy of Sciences, 1996.
Знайти повний текст джерелаConstruction of murine interleukin-12 retroviral Vectors: Implications for gene therapy of hematologic malignancies. Ottawa: National Library of Canada, 1996.
Знайти повний текст джерелаЧастини книг з теми "Interleukin-12"
Kaufman, Howard L., and Neal Dharmadhikari. "Interleukin-12." In Cancer Therapeutic Targets, 345–59. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4419-0717-2_144.
Повний текст джерелаDieckman, Tessa, Antonie Zwiers, Georg Kraal, and Gerd Bouma. "Interleukin 12." In Compendium of Inflammatory Diseases, 709–14. Basel: Springer Basel, 2016. http://dx.doi.org/10.1007/978-3-7643-8550-7_220.
Повний текст джерелаBukowski, Ronald M., and Charles Tannenbaum. "Interleukin-12." In Melanoma, 221–34. Totowa, NJ: Humana Press, 2002. http://dx.doi.org/10.1007/978-1-59259-159-6_8.
Повний текст джерелаKaufman, Howard L., and Neal Dharmadhikari. "Interleukin-12." In Cancer Therapeutic Targets, 1–15. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6613-0_144-1.
Повний текст джерелаDieckman, Tessa, Antonie Zwiers, Georg Kraal, and Gerd Bouma. "Interleukin 12." In Encyclopedia of Inflammatory Diseases, 1–7. Basel: Springer Basel, 2014. http://dx.doi.org/10.1007/978-3-0348-0620-6_220-1.
Повний текст джерелаBryan, Shannon, Michiko Kobayashi, and Sanjiv Sur. "Interleukin-12, Interleukin-18 and Interferon-γ." In New Drugs for Asthma, Allergy and COPD, 274–78. Basel: KARGER, 2001. http://dx.doi.org/10.1159/000062155.
Повний текст джерелаPile, Kevin D., Garry G. Graham, and Stephen M. Mahler. "Interleukin-12/23 Inhibitors: Ustekinumab." In Compendium of Inflammatory Diseases, 714–17. Basel: Springer Basel, 2016. http://dx.doi.org/10.1007/978-3-7643-8550-7_232.
Повний текст джерелаPile, Kevin D., Garry G. Graham, and Stephen M. Mahler. "Interleukin-12/23 Inhibitors: Ustekinumab." In Encyclopedia of Inflammatory Diseases, 1–3. Basel: Springer Basel, 2015. http://dx.doi.org/10.1007/978-3-0348-0620-6_232-1.
Повний текст джерелаAulitzky, W. E., and C. Huber. "Interleukin-12: Biology and Clinical Studies." In Symposium in Immunology VI, 111–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60562-8_10.
Повний текст джерелаFernández-Ruiz, Mario. "Interleukin-12 and -23 Targeted Agents." In Infectious Complications in Biologic and Targeted Therapies, 199–217. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-11363-5_11.
Повний текст джерелаТези доповідей конференцій з теми "Interleukin-12"
"03 Targeting interleukin 12/23." In 8th ANNUAL MEETING OF THE LUPUS ACADEMY, Warsaw, Poland, September 6–8, 2019. Lupus Foundation of America, 2019. http://dx.doi.org/10.1136/lupus-2019-la.15.
Повний текст джерелаConway, R., L. O’Neill, P. Gallagher, G. McCarthy, C. Murphy, D. Veale, U. Fearon, and E. Molloy. "SAT0542 Interleukin-12 and interleukin-23 are key pathogenic players in giant cell arteritis." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.2850.
Повний текст джерелаCanataroglu, A., E. Erken, and R. Gunesacar. "FRI0165 Serum levels of interleukin-12 in behcet’s disease." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.225.
Повний текст джерелаVo, Jimmy Nhu. "Abstract 1535: Intratumoral chitosan/interleukin-12 immunotherapy reduces breast cancer metastasis." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1535.
Повний текст джерелаUrsic Valentinuzzi, K., U. Kamensek, S. Kos, S. Kranjc Brezar, M. Cemazar, and G. Sersa. "P08.03 Interleukin-12 gene electrotransfer as an adjuvant immunotherapy to electrochemotherapy." In iTOC9 – 9th Immunotherapy of Cancer Conference, September 22–24, 2022 – Munich, Germany. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-itoc9.49.
Повний текст джерелаIshihara, Jun, Aslan Mansurov, and Jeffrey Hubbell. "1227 Eliminating the immunotoxicity of interleukin-12 through protease-sensitive masking." In SITC 37th Annual Meeting (SITC 2022) Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-sitc2022.1227.
Повний текст джерелаSmith, Sean, Jack Baltz, Bhanu Koppolu, Sruthi Ravindranathan, Khue Nguyen, and David Zaharoff. "Abstract B020: Effector cells in chitosan/interleukin-12 immunotherapy of bladder tumors in mice." In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-b020.
Повний текст джерелаYang, Xi, Ashlee Tietje, Xianzhong Yu, and Yanzhang Wei. "Abstract 4874: Interleukin-12/FasTI: A novel bi-functional fusion protein for cancer immunotherapy." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-4874.
Повний текст джерелаCheema, Tooba A., Hiroaki Wakimoto, Samuel Rabkin, and Robert L. Martuza. "Abstract 5389: Oncolytic herpes simplex virus expressing interleukin-12 for treating glioma stem cells." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-5389.
Повний текст джерелаSimkin, Guillermo O., Julia G. Levy, and David W. C. Hunt. "Interleukin-12 reverses the inhibitory impact of photodynamic therapy (PDT) on the murine contact hypersensitivity response." In BiOS '98 International Biomedical Optics Symposium, edited by Thomas J. Dougherty. SPIE, 1998. http://dx.doi.org/10.1117/12.308134.
Повний текст джерелаYou might want to see the page in this language: English.