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Добірка наукової літератури з теми "It's Used In Sustained Release"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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Статті в журналах з теми "It's Used In Sustained Release"

Vaishali, S. Kadam G. R. Shendarkar. "ROLE OF NATURAL POLYMER IN SUSTAINED AND CONTROLLED RELEASE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 01 (2017): 7390–400. https://doi.org/10.5281/zenodo.1006885.

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Now a day there has been an important development in different dosage forms for existing and newly designed drugs and natural products, and synthetic as well as semi-synthetic excipients always need to be used for a variety of purposes. Gums and mucilages are widely used as natural materials for conventional and novel dosage forms. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. Moreover, the tremendous orientation of Pharmaceutical world towards these naturally derived polymers has become a subject

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Shanker, Oma, Arsh Chanana, Pooja Gupta, et al. "Niosomal Drug Delivery System used in Tuberculosis." Journal of Drug Delivery and Therapeutics 14, no. 3 (2024): 218–26. http://dx.doi.org/10.22270/jddt.v14i3.6475.

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Niosomes are artificially manufactured vesicles made of Cholesterol and Non-ionic surfactant. Their capacity to encapsulate a broad variety of pharmaceuticals and shield them from deterioration has piqued interest in drug delivery. Niosomes have demonstrated a possible use in the administration of anti-tuberculosis medications. Worldwide, tuberculosis is a serious public health concern. Even with advances in science and technology, tuberculosis remains a persistent problem.Niosomes can encapsulate anti-TB drugs, protecting them from enzymatic degradation and allowing for sustained release. Res

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Chourey, Nikita, and Khushi Chouksey. "Formulation and Evaluation of Enteric Coated Matrix Tablets of Mesalamine for Inflammatory Bowel Disease." Journal of Drug Delivery and Therapeutics 12, no. 1 (2022): 56–61. http://dx.doi.org/10.22270/jddt.v12i1.5176.

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Mesalamine is a gold standard anti-inflammatory drug used to treat inflammatory bowel illnesses. It's usually used to treat and keep Ulcerative Colitis in remission in mild to moderate cases. Mesalamine is rapidly cleared from circulation after being consumed orally, with an elimination half-life of only one hour. Oral intake of delayed or slow released matrix formulations can acquire therapeutic concentration in the intestines. The goal of this study was to use guar gum as a carrier to develop colon-specific delivery methods for mesalamine. The matrix tablets were made using the direct compre

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*Ramachandra, M. Koli Manojkumar S.Patil Sandhyarani S. Kamble Meghraj A. Patil Shashikant P. Jokar Bharat B. Garande. "DEVELOPMENT AND EVALUATION OF RABEPRAZOLE GASTRORETENTIVE DRUG DELIVERY SYSTEM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 06 (2018): 5047–59. https://doi.org/10.5281/zenodo.1286333.

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The present study was undertaken with an aim to design, develop and evaluate floating tablet of Rabeprazole, which release the drug in a sustained manner over a period of 12 hours. In this resesrch work used hydroxy propyl methyl cellulose(HPMC K15M), gas generating agent sodium bicarbonate and citric acid. The high level of HPMC K15M and citric acid favors preparation of floating tablet Rabeprazole. The tablets were prepared by direct compression techniques and evaluated thickness, hardness, weight variation, friability, floating lag time and In-vitro drug release studies indicated that the f

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Pooja Mallya, Gowda D V, Mahendran B, Bhavya M V, and Vikas Jain. "Recent developments in nano micelles as drug delivery system." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 176–84. http://dx.doi.org/10.26452/ijrps.v11i1.1804.

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Targeting of the drug directly to the cells, tissues, or organs with no impact on healthy cells is a challenge. In the current era, it's been made possible by therapeutic interventions. The novel drug delivery systems such as nano particulates, liposomes, aquasomes, phytosomes, dendrimers, nano sponges, nano micelles are developed. Nano micelles are developed for efficient targeting and are currently in trend as therapeutic carriers of water-insoluble drugs. Micelles are self-assembling Nano-sized colloidal particles with a hydrophobic core and hydrophilic shell. Among the micelle-forming comp

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Vasanth, B.*1 A. Vasanthan2 Senthilkumar K. L.3. "Formulation And Evalution Of Nanoparticles Loaded Topical Drug Delivery System Of An Anti-Fungal Drug." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 823–38. https://doi.org/10.5281/zenodo.11208130.

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Ketoconazole is a synthetic antifungal agent belonging to the group of triazole. Itis one of the commonly used antifungal agents for the treatment of local and systemic fungal infections. It is a BCS class II drug (low solubility and high permeability). On oral administration, its bioavailability is low due to poor aqueous solubility. The objective of this work is to prepare Ketoconazole nanoparticles and then incorporated into the freshly prepared gel for transdermal delivery, because patients with Skin infection such as athlete's foot, jock itch, ringworm, and certain kinds of dandruff. The

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Gupta, Kajal. "Formulation and Evaluation of Metformin Using Fenugreek Seed Mucilage Used as a Natural Polymer." International Journal of Advanced Pharmaceutical Sciences and Research 4, no. 4 (2024): 35–41. http://dx.doi.org/10.54105/ijapsr.f4051.04040624.

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The major goal of this study was to develop and test metformin sustained release tablets employing fenugreek seed mucilage (FSM) as a new binder, as opposed to standard polymers such as xanthan gum and HPMC. The study shows how FSM provides sustained medication release while keeping metformin physicochemical characteristics. The sustained-release matrix tablets were made on a laboratory scale utilizing the wet granulation process. 5 batches were created, each with varying quantities of fenugreek seed mucilage, xanthan gum, and HPMC. To examine the tablet's physical properties and consistency,

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Singh, Neha, Durga Pandey, Nilesh Jain, and Surendra Jain. "Formulation and In Vitro Evaluation of Bilayer Tablets of Lansoprazole and Amoxycillin Trihydrate for the Treatment of Peptic Ulcer." Journal of Drug Delivery and Therapeutics 11, no. 1 (2021): 23–31. http://dx.doi.org/10.22270/jddt.v11i1.4481.

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The present work involves the formulation development, optimization and In-vitro evaluation of bilayer tablet containing Lansoprazole in the immediate release layer and Amoxycillin in the sustained release layer, using sodium starch glycolate as a super disintegrant for the immediate release layer and the hydrophilic matrix HPMC K100M, hydrophobic matrix Ethyl cellulose are used in the sustained release layer. Bilayer tablet showed as initial burst effect to provide dose of immediate release layer Lansoprazole to control the acid secretion level and the sustained release of Amoxycillin for 24

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Yani, Tan, Lin Junming, Zhang Zhen, He Rongrong, and Li Sha. "Studies on Sustained Release Tablets of Theacrine with Erodible Matrix Material." Journal of Pharmaceutical and Biomedical Sciences 11, no. 03 (2021): 60–71. https://doi.org/10.5281/zenodo.4818212.

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<strong>Background </strong>Theacrine is a purine alkaloid with sedative, hypnotic and liver protection effects, which was investigated in treatment of insomnia, liver damage and hepatic steatosis. These are generally chronic diseases needing long-term medication. Sustained release preparations have good effect and compliance in prolonged treatment. <strong>Aim</strong> This study aimed to develop theacrine sustained release tablets using wax matrix material with simple preparing process. Methods: The content assay method of theacrine was developed using UV-visible spectrophotometry, and the m

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Kumari, Satish, Anchal Puri, Dhruv Dev, DN Prasad, and ,. Monika. "A review on polymers in natural or modified form used in sustained release tablet." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 870–73. http://dx.doi.org/10.22270/jddt.v9i3-s.2843.

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Tablet is a solid dosage form which is used to deliver the drug to the body to make pharmacological action. The oral dosage form should disperse into small particles to deliver active ingredients in the body, the disperse time of the dosage form depends on the ingredients which are used in the tablet. To make the tablet disintegrate slow usually sustained release agents are used. The sustained release tablets helps in maintaining the drug concentration in the body for the higher time. In this review article various polymers of natural origin and their modified forms are studied, which can be u

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Частини книг з теми "It's Used In Sustained Release"

Wang, Chi-Yuen, and Michael Manga. "Groundwater Level." In Lecture Notes in Earth System Sciences. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-64308-9_6.

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AbstractGroundwater level has long been known to respond to earthquakes; several types of response have been documented. Advances in the last decade were made largely through the studies of water-level response to Earth tides and barometric pressure. These studies have demonstrated that the hydraulic properties of groundwater systems are dynamic and change with time in response to disturbances such as earthquakes. This approach has been applied to estimate the permeability of several drilled active fault zones, to identify leakage from deep aquifers used for the storage of hazardous wastewater

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Marrero-Figueroa, Neisaliz, and Ettore Crimi. "BiPAP, Airway Pressure Release Ventilation, and Prone Ventilation." In Advanced Anesthesia Review, edited by Alaa Abd-Elsayed. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197584521.003.0106.

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Abstract Biphasic positive airway pressure (BiPAP), airway pressure release ventilation (APRV), and prone ventilation are used as rescue therapies for refractory hypoxemia in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). BiPAP and its variant, APRV, allow the patient to breathe spontaneously at two levels of continuous positive airway pressure (CPAP). BiPAP uses conventional I:E ratios, while APRV is an inverse ratio ventilation. The significant advantages of these two modes of ventilation are the preservation of spontaneous breathing, improved ventilati

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Mogal, Rajendra T., and Moreshwar P. Patil. "Microencapsulation as a Tool for Controlled Drug Delivery." In Novel Drug Delivery Systems (Part 1). BENTHAM SCIENCE PUBLISHERS, 2024. https://doi.org/10.2174/9789815274165124010009.

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Controlled drug delivery systems, which release drug/s in a predetermined manner, offer numerous advantages over conventional drug delivery systems. These advantages include improved bioavailability, reduced dose frequency, minimized fluctuations in plasma drug concentration, and sustained drug release. The major drawback of the unit dosage form is dose dumping, which can be effectively overcome by multiple unit dosage forms like microcapsules. The microencapsulation technique involves enclosing drug/s by a thin coating shell, and the resultant product is referred to as microcapsules. This tec

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Neha, Chopra, M. Alagusundaram, Bhattacharya Vijeta, et al. "LIPONOVEL PREPARATION OF MICROENCAPSULATION DRUG DELIVERY SYSTEM." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 5. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bapn5ch49.

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There are several advantages when contrasting innovative drug delivery systems with conventional multi-dose therapy. Research aimed at developing novel drug delivery methods has given a lot of attention to controlled release and sustained release dosage forms. A lot of work is currently being done to deliver the medicine in a way that will have the greatest positive effects. There are numerous techniques for continuously regulating the delivery of a therapeutic substance to the target area. One such method is the use of microspheres as drug delivery systems. During the microencapsulation proce

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Desai, Jagruti L., Pal B. Patel, Ashwini D. Patel, Richa R. Dave, Swayamprakash Patel, and Pranav Shah. "Implantable Drug Delivery." In Novel Drug Delivery Systems (Part 2). BENTHAM SCIENCE PUBLISHERS, 2024. https://doi.org/10.2174/9789815313567124010008.

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Miniaturized systems, known as implantable drug delivery systems, are used to administer medicinal medicines to specific sites within the body. They are made of biocompatible substances that enclose the drug payload and control its kinetics of release, enabling sustained delivery. These systems provide a number of benefits by avoiding the drawbacks of oral drugs and conventional injectable techniques, including increased bioavailability, fewer systemic side effects, and improved patient adherence. The key characteristics and elements of implanted drug delivery systems, such as the drug reservo

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Modi, Chetna, Nikita Udhwnai, Pranav Shah, and Arjun Joshi. "Abridgment of Nanotechnology in Skin Cancer Treatment: Current Trends and Future Outlook." In Role of Nanotechnology in Cancer Therapy. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815079999123010011.

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This chapter focuses on skin cancer, which is represented by the accumulation of cells in one part of the skin. It enhances the form of the cells which line up along the membrane and separates the deep layer of the skin from the superficial layer. The recent skin cancer treatment includes surgical or excision biopsy, chemotherapy, targeted therapy, Mohs micrographic surgery, radiation therapy, photodynamic therapy, therapeutic hyperthermia, immunotherapy, etc. The drawback of skin cancer treatment with these therapies are skin irritation at the site of treatment and variation in the skin color

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Kirsh, Kenneth L., Anya Kerith Vice, and Steven D. Passik. "History of Opioids and Opiophobia." In Pain and Chemical Dependency. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195300550.003.0001.

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Abstract Among the remedies which it has pleased Almighty God to give to man to relieve his sufferings, none is so universal and so efficacious as opium. The field of pain management has arrived at a crossroads in history with regard to the topic of opioid analgesics. Over the past several years, one of the most widely used opioid pharmaceuticals, OxyContin, had become a popular alternative to street drugs such as heroin. Called ‘‘Hillbilly Heroin’’ because of its popularity in Appalachia and other rural areas, it is available as an oral preparation, although illicit users tend to crush the ta

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Kumar, B. S. "Ion Exchange Resins as Carriers for Sustained Drug Release." In Ion Exchange Resins. Materials Research Forum LLC, 2023. http://dx.doi.org/10.21741/9781644902219-6.

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Ion exchange resins are water-insoluble cross-linked polymers conventionally used in chemical engineering to separate and purify substances from fluid mixtures and for the separation of gases. They are used in the pharmaceutical industry as a carrier for controlled drug delivery systems. Sustained drug release involves the release of the drug at a predetermined rate into the target system and helps maintain a constant drug concentration for a specified period. At present ion-exchange resins are widely studied and used as drug-delivery agents. Ion-exchange fibers are shought as an alternative d

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Bissett, John. "Class as the production of scarcity: wage, price, debt, food." In It's Not Where You Live, It's How You Live. Policy Press, 2023. http://dx.doi.org/10.1332/policypress/9781447368212.003.0011.

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In this chapter I make the case for the importance and significance of social class to the lives of public housing tenants. Class may well provide homologous conditions and solidarity, but it is also the great divider of society into those who work and those who benefit from those who work. The Bridgetown Estate is a microcosm of class in Ireland. Class originates and is sustained in relations between groups, much more than it is something based on static positions. I argue in this chapter that class is both materially and morally significant to the lives of the people of the Bridgetown Estate

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Özkale, Evrim. "Bioremediation of Wastewaters of Sugarcane Biorefineries." In Sugarcane - Its Products and Sustainability [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.108069.

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In addition to sugar, sugarcane biorefineries emerge as the integration of different sugarcane industries and produce several wastes and wastewaters that are disposed into the environment. In biorefineries and other facilities, these wastes are used to produce several chemicals, including bioplastics and bioethanol. However, these industries use a greater amount of fresh water and their effluents, which have high amounts of solids and are released mostly into water or used for crop irrigation. Inadequately treated and indiscriminately disposing and discharging of effluents to the environment c

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Тези доповідей конференцій з теми "It's Used In Sustained Release"

Ansari, Mohammad Javed, Aziz Unnisa, Anshul Singh, Devvret Verma, Rahul Kanaoujiya, and Jose Luis Arias Gonzales. "Application of Porous Nanomaterials for Sustained and Targeted Drug Release." In International Conference on Recent Advancements in Biomedical Engineering. Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-b2484c.

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Patients must take significant doses of drugs to acquire the therapeutic effects required for disease therapy due to the absence of selectivity and accessibility of medicinal molecules. Drugs contain a range of drug carriers that are available to transport therapeutic chemicals to the targeted issues in the body. Mesoporous materials are choice for overcoming the aforementioned issues and producing effects in a predictable and long-term way. Because of its chemical characteristics, thermal stability, & biocompatibility, mesophoric nanoparticles are commonly utilized as release reagents. Th

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Soloiu, Valentin, James Willis, Coleman Norton, Zachary Davis, Tristan Graham, and Austin Nobis. "Comprehensive Investigation of Combustion Characteristics, Emissions, and Tribological Properties of Synthetic Kerosene (S8) in a CVCC and CRDI Research Engine." In WCX SAE World Congress Experience. SAE International, 2025. https://doi.org/10.4271/2025-01-8443.

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<div class="section abstract"><div class="htmlview paragraph">There is a need to reduce both the greenhouse gas emissions of internal combustion engines, and the reliance on traditional fossil fuels like Ultra Low Sulfur Diesel (ULSD). In this research, a synthetic paraffinic kerosene fuel, designated S8 and created from natural gas feedstocks using the Fischer-Tropsch process was investigated to determine its autoignition and combustion characteristics, emissions, and tribological properties. This fuel, S8, was found to have a Derived Cetane Number (DCN) of 62, which reflects a sh

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Momeni, Amir Farid, Robert J. Peterman, B. Terry Beck, Chih-Hang John Wu, and Naga Narendra B. Bodapati. "Effect of Concrete Release Strength on the Development Length and Flexural Capacity of Members Made With Different Prestressing Strands." In 2016 Joint Rail Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/jrc2016-5762.

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Load tests were conducted on pretensioned members made with five different strands (three 7-wire strands and two 3-wire strands) to determine the effect of concrete release strength on the development length and flexural capacity of members. Strands named generically SA, SC, SD, SE and SF and they were all indented except SA (no surface indentation). All strands had diameter of 3/8″ (9.52 mm) except SC which had diameter of 5/16″ (7.94 mm). Among all types of strands used in manufacturing of test prisms, SC and SF were 3-wire strands, while SA, SD and SE were 7-wire strands. A consistent concr

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Lee, C. Y., and R. S. Cant. "CFD Investigation of Hydrodynamic and Acoustic Instabilities of Bluff-Body Stabilized Turbulent Premixed Flames." In ASME Turbo Expo 2014: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/gt2014-25507.

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Combustion instabilities in propulsion systems are often manifested through high amplitude pressure oscillations that can severely compromise performance and even lead to mechanical failure. Such instability arises from the development of large-scale coherent structures and their breakdown into fine scale turbulence that can alter the flame structure and affect turbulent mixing. When in phase with the pressure, the modulated heat release rate fluctuations can drive the system to the point where it reaches a limit cycle. Using high fidelity CFD, the present investigation describes the occurrenc

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Wei, Sheng, Brandon Sforzo, and Jerry Seitzman. "Fuel Composition Effects on Forced Ignition of Liquid Fuel Sprays." In ASME Turbo Expo 2018: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/gt2018-77196.

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In gas turbine combustors, ignition is achieved by using sparks from igniters to start a flame. The process of sparks interacting with fuel/air mixture and creating self-sustained flames is termed forced ignition. Physical and chemical properties of a liquid fuel can influence forced ignition. The physical effects manifest through processes such as droplet atomization, spray distribution, and vaporization rate. The chemical effects impact reaction rates and heat release. This study focuses on the effect of fuel composition on forced ignition of fuel sprays in a well-controlled flow with a comm

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Lohrmann, Martin, Horst Bu¨chner, Nikolaos Zarzalis, and Werner Krebs. "Flame Transfer Function Characteristics of Swirl Flames for Gas Turbine Applications." In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38113.

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For the suppression or reduction of self-sustained combustion instabilities, modifications of the burner outlet conditions, that strongly influence the dynamic flame response, seem to be the most promising way. Therefore, to derive a detailed physical understanding of the feedback mechanisms the dynamic flame response characteristics, quantified by flame transfer functions, are required in dependence of flame type and operation conditions of the combustor. In the present paper measurements of flame transfer functions of an industrial, full-scale prototype gas turbine burner are discussed. For

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Stow, Simon R., and Ann P. Dowling. "A Time-Domain Network Model for Nonlinear Thermoacoustic Oscillations." In ASME Turbo Expo 2008: Power for Land, Sea, and Air. ASMEDC, 2008. http://dx.doi.org/10.1115/gt2008-50770.

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Lean premixed prevaporised (LPP) combustion can reduce NOx emissions from gas turbines, but often leads to combustion instability. Acoustic waves produce fluctuations in heat release, for instance by perturbing the fuel-air ratio. These heat fluctuations will in turn generate more acoustic waves and in some situations linear oscillations grow into large amplitude self-sustained oscillations. The resulting limit cycles can cause structural damage. Thermoacoustic oscillations will have a low amplitude initially. Thus linear models can describe the initial growth and hence give stability predicti

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Vaysse, Nicolas, Daniel Durox, Ronan Vicquelin, Sébastien Candel, and Antoine Renaud. "Analysis of Thermo-Acoustic Instabilities Induced by Hydrogen Swirling Flames." In ASME Turbo Expo 2024: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2024. http://dx.doi.org/10.1115/gt2024-123877.

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Abstract A considerable research effort has concerned combustion dynamics of systems fed with hydrocarbon fuels. The case of pure hydrogen/air flames deserves to be specifically considered because hydrogen is highly reactive, has a tendency to develop thermo-diffusive instabilities, is envisaged in many future applications, most notably in gas turbines and is less well documented. Thermo-acoustic instabilities of pure hydrogen flames are here investigated in a configuration where hydrogen is injected in-crossflow in a swirling stream of air. The study is focused on operating conditions that le

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Hatfield, Jonathan M., and Richard B. Peterson. "A Catalytically Sustained Microcombustor Burning Propane." In ASME 2001 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/imece2001/aes-23634.

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Abstract The performance of a catalytically sustained microcombustor was investigated. The reactants for combustion were air and propane, which were mixed together and delivered to the end of a bayonet-style, heat recirculating combustor having a reaction volume measuring approximately 0.25 mm3. Platinum wire in the shape of a coil was used as an active surface to catalyze the exothermic reactions. Measurements of temperature and reactant flow rate were made during the study. Results show that propane can be burned in a self-sustaining fashion in the microcombustor with heat release rates as l

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Meidan, Rina, and Robert Milvae. Regulation of Bovine Corpus Luteum Function. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604935.bard.

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The main goal of this research plan was to elucidate regulatory mechanisms controlling the development, function of the bovine corpus luteum (CL). The CL contains two different sterodigenic cell types and therefore it was necessary to obtain pure cell population. A system was developed in which granulosa and theca interna cells, isolated from a preovulatory follicle, acquired characteristics typical of large (LL) and small (SL) luteal cells, respectively, as judged by several biochemical and morphological criteria. Experiments were conducted to determine the effects of granulosa cells removal

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Maki, Ryan, Kristen Patterson, Joseph Amundson, et al. Little Shoepack Lake muskellunge (Esox masquinongy) population estimate and genetic evaluation of muskellunge from Shoepack and Little Shoepack lakes. National Park Service, 2024. http://dx.doi.org/10.36967/2305092.

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Little Shoepack and Shoepack lakes in Voyageurs National Park, Minnesota, are home to native populations of Muskellunge (Esox masquinongy). Due to the small size of these lakes, 20.8 ha and 123 ha, respectively, and the associated, predicted small size of these Muskellunge populations, resource managers are concerned about their persistence. A recent population assessment completed for Shoepack Lake Muskellunge indicated that the population may be below a threshold at which a genetic bottleneck could threaten its persistence. Since Little Shoepack Lake is approximately 20% of the size of Shoep

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Effect of Spark Discharge Duration and Timing on the Combustion Initiation in a Lean Burn SI Engine. SAE International, 2021. http://dx.doi.org/10.4271/2021-01-0478.

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Meeting the increasingly stringent emission and fuel efficiency standards is the primary objective of the automotive research. Lean/diluted combustion is a promising avenue to realize high-efficiency combustion and reduce emissions in SI engines. Under the diluted conditions, the flame propagation speed is reduced because of the reduced charge reactivity. Enhancing the in-cylinder charge motion and turbulence, and thereby increasing the flame speed, is a possible way to harness the combustion process in SI engines. However, the charge motion can have a significant effect on the spark ignition

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