Статті в журналах: "Kulin Treaty"

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Kuin, Inger N. I. "Een ondeugende Diogenes." Lampas 52, no. 2 (June 1, 2019): 139–51. http://dx.doi.org/10.5117/lam2019.2.003.kuin.

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Summary In the corpus of apocryphal Cynic letters those attributed to Diogenes stand out: they form the bulk of the letters and they are the most humorous. This corresponds with representations of him as a provocateur elsewhere in imperial Greek literature. This article focuses on the topic of sex in Diogenes’ letters, and answers two main questions: first, whether the sexual humor of the letters is more risqué than what we find in the other sources; second, how this sexual humor contributes to the overall purpose of the apocryphal Diogenes letters. I suggest that even though in the letters euphemistic language persists, they treat the Diogenes anecdotes about sex in greater detail than anywhere else. The provocative, risqué humor contained in these anecdotes would serve to entice and entertain audiences in order to get them engaged in Cynic philosophy.

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Pappa, Suryadi, Abdul Wahid Jamaluddin, and Adryani Ris. "THE COCOA (THEOBROMA CACAO L.) POD HUSK EXTRACT OF PLANTATION WASTE PRODUCT HAS A POTENTIAL EFFECT AS NATURAL ACARICIDE ON BOOPHILUS MICROPLUS TICKS." Jurnal Veteriner 21, no. 4 (December 30, 2020): 611–16. http://dx.doi.org/10.19087/jveteriner.2020.21.4.611.

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This study was aims to exploit the potential waste of cocoa pod (Theobroma cacao L.) as a natural acaricide in ticks (Boophilus microplus). The study was conducted with a two-variable completely randomized design (CRD) with two repetitions. The sample does not differentiate between sex, body weight, and length of about 0.8 - 1 cm. Each 5 ticks were treated as follows: treat 1 extract of 10% cocoa pod husk; treatment 2 20% cocoa pod skin extract; treatment 3 30% cocoa pod husk extract; treatment 4 negative control; treat 5 positive controls. In the first variable the tick was treated with methanol extract, while in the second variable the ethanol extract was treated with 10%, 20%, 30% respectively, negative control and positive control. In treatment I used 25 ticks plus treatment II 25 ticks. Each treatment was repeated to avoid data bias so that a total of 100 ticks were used. The results showed that the cocoa pod husk extract had the best killing power at a concentration of 30% with methanol solvent at 6.21 hours while ethanol solvent at 5.91 hours. The use of extraction materials has not been able to compensate for the use of synthetic materials that can kill in minutes.

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Wulandari, Putri. "Asam Traneksamat Oral Sebagai Terapi Melasma." Cermin Dunia Kedokteran 48, no. 4 (April 1, 2021): 255. http://dx.doi.org/10.55175/cdk.v48i4.1474.

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Melasma adalah kelainan pigmentasi kulit didapat yang bersifat kronis, cenderung rekuren, serta sulit diobati. Asam traneksamat telah dilaporkan dapat menurunkan skor MASI dan memberikan perbaikan klinis.Melasma is an acquired chronic skin pigmentation disorder, tend to recur, and difficult to treat. Oral tranexamic acid has been reported can reduce MASI score and give clinical improvement.

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Napfiah, Siti, Asri Putri Anugraini, and Farizha Irmawati. "PKM PENDAMPINGAN PEMBUATAN ABON KULIT PISANG DI KABUPATEN TULUNGAGUNG." PAMBUDI 2, no. 1 (September 29, 2018): 48–53. http://dx.doi.org/10.33503/pambudi.v2i1.271.

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Program society partnership is training abon's makings banana skin at Regency Tulungagung aims to give science and training makes a new innovation product namely abon banana skin in order to develop Regency citizen effort Tulungagung that not only utilize its banana only. At chooses two flaky producer partners bananas at Regency Tulungagung to been given training abon's makings that gets banana skin raw product. Two elected partner gets location at Kauman and Boyolangu. Two this effort partner did not utilize its banana skin eventually well-nigh every day making banana so banana skin flaky piles. By this program, given by science newing to that society banana skin can be utilized as a product that valuably namely abon banana skin. Reasonable banana skin to be made food product because banana skin has goodly nutrient content lovely. Abon reasonably to been kept up because top abon that than so long without bahna preservative and is liked by all society circle. Society devotion program this executed beginning month of February 2018. Via test-driving activity sort recipe and discussion with partner therefore at finds recipe to make abon banana skin who can get long-lasting, having a real treat, pretty color, and texture that nicely corresponds to banana skin type that is at partner effort place. Activity on programs it to get positive comment of Tulungagung's Regency citizen. They really enjoy following this activity.

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Hermawati, Hermawati, and Ika Silvitasari. "PELATIHAN PERAWATAN LUKA PADA KADER DI KELURAHAN KEPATIHAN KULON JEBRES SURAKARTA." GEMASSIKA : Jurnal Pengabdian Kepada Masyarakat 6, no. 1 (April 6, 2022): 79. http://dx.doi.org/10.30787/gemassika.v6i1.761.

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Background: The incidence of injuries is increasing every year, both acute and chronic wounds. A recent study in America showed the prevalence of patients with wounds was 3.5% per 1000 population. This requires wound care materials that must be adapted to the characteristics of the patient's wound. It is hoped that by increasing the understanding and skills of cadres, families can carry out wound care at home. Targets and outputs: dasa wisma cadres and dasa wisma members in Kepatihan Kulon Jebres Village, Surakarta. The benefit of this activity is to increase knowledge and change the attitude of the dasa wisma cadres in wound care training. The output of this activity is skills on how to treat wounds and know the signs of infection in wounds. Implementation method: lectures, simulations and demonstrations. Results and Conclusions: Wounds with any condition must be treated properly so as not to cause infection to cause amputation. One of those who play a role in this is the family. The results of the evaluation in the last week showed that the wound was regenerating. Keywords ;Training; injury cure; Cadre

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Setiawan, Irvan. "PENGOBATAN TRADISIONAL DI DESA LEMAHABANG KULON, KEC. LEMAHABANG, KAB. CIREBON." Patanjala : Jurnal Penelitian Sejarah dan Budaya 10, no. 1 (March 4, 2018): 83. http://dx.doi.org/10.30959/patanjala.v10i1.323.

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Pengobatan Modern dan pengobatan tradisional merupakan dua jenis pengobatan yang kerap dipakai untuk mengatasi sakit yang diderita. Masing-masing jenis pengobatan memiliki keampuhan dan peminatnya. Indonesia sudah mensahkan obat tradisional sebagai media alternatif untuk mengobati masyarakat. Obat tradisional merupakan sebuah kearifan lokal dari generasi terdahulu yang didapat melalui berbagai proses untuk membuktikan keampuhannya. Penelitian yang menggunakan metode deskripsi kualitatif ini bertujuan untuk menggali sumber pengetahuan dan jenis pengobatan tradisional di lokasi penelitian. Diperoleh hasil bahwa garis keturunan dan keingintahuan menjadi latar belakang penyembuh dalam memeroleh pengetahuan pengobatan tradisional. Rasa percaya terhadap cara pengobatan, ikhlas, dan memasrahkan diri pada Sang Pencipta menjadi unsur utama yang harus dimiliki pasien dan penyembuh untuk mengobati penyakit yang sesuai dengan kondisi sosial budaya setempat. Modern and traditional medicine are two types of treatment that are often used to overcome illness. Each type of treatment has the power and also the followers. Indonesia has legalized traditional medicine as an alternative media. Traditional medicine is a local wisdom of previous generations that gained through various processes to prove its ability. The research uses qualitative description method to explore and find the type of traditional medicine in the research location. The result is obtained that the lineage and curiosity become the background of the healer in obtaining knowledge of traditional medicine. Belief in the way of treatment, sincerity, and surrender to the Creator becomes the main element that must be possessed by the patient and the healer to treat the disease according to local socio-cultural conditions.

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Fatah, Abdul Fatah. "LIVING QUR’AN: TRADISI WIRID AL-MA’TSŪRĀT DI SMAIT ABU BAKAR BOARDING SCHOOL KULON PROGO." Jurnal At-Tibyan: Jurnal Ilmu Alqur'an dan Tafsir 5, no. 1 (June 28, 2020): 1–19. http://dx.doi.org/10.32505/at-tibyan.v5i1.1398.

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This article discusses about the Living Quran study of recitation of wirid al-Ma’tsūrāt at Abu Bakar Senior Boarding School Kulon Progo. It focuses on the practice of wirid al-Ma’tsūrāt which is read routine by students at the school. This phenomenon, which has been going on since the school was founded, has positive values for students. They feel the positive impact of the tradition of reciting it in accordance with the function of the Koran as al-dzikr (to remembrance of Allah) and al-syifā’ (to treat for illness). With the Living Quran method, which is presented by descriptive-analitically method the result is indicate that interaction with the Koran in the form of recitation can provide peace of mind for the reader, whether recited individually or in congregation.

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Fatah, Abdul Fatah. "LIVING QUR’AN: TRADISI WIRID AL-MA’TSŪRĀT DI SMAIT ABU BAKAR BOARDING SCHOOL KULON PROGO." JURNAL At-Tibyan Jurnal Ilmu Alquran dan Tafsir 5, no. 1 (June 28, 2020): 1–19. http://dx.doi.org/10.32505/tibyan.v5i1.1398.

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This article discusses about the Living Quran study of recitation of wirid al-Ma’tsūrāt at Abu Bakar Senior Boarding School Kulon Progo. It focuses on the practice of wirid al-Ma’tsūrāt which is read routine by students at the school. This phenomenon, which has been going on since the school was founded, has positive values for students. They feel the positive impact of the tradition of reciting it in accordance with the function of the Koran as al-dzikr (to remembrance of Allah) and al-syifā’ (to treat for illness). With the Living Quran method, which is presented by descriptive-analitically method the result is indicate that interaction with the Koran in the form of recitation can provide peace of mind for the reader, whether recited individually or in congregation.

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9

Muharram, Luthfia Hastiani, Fauzia Ningrum Syaputri, Wulan Pertiwi, and Rizki Fika Saputri. "Aktivitas Antibakteri Ekstrak Bawang Hitam Variasi Waktu Aging Terhadap Pencegahan Dysbiosis Kulit Penyebab Jerawat." Jurnal Sains dan Kesehatan 4, no. 2 (April 30, 2022): 181–88. http://dx.doi.org/10.25026/jsk.v4i2.1035.

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Skin diseases, including acne, can be caused by a microbial imbalance (dysbiosis). The specific bacteria involved in acne dysbiosis are Cutibacterium (Propionibacterium) acnes and Staphylococcus epidermidis. Black garlic has better potential to be alternative antibiotic and chemical to curing ance and maintaining skin health, because it has antimicrobial potential and can inhibit the decrease in collagen deposition on the skin. These potentials can be alternative of antibiotics and chemicals to treat acne and maintain healthy skin. This study aimed to determine the antibacterial activity of black garlic extract against bacteria that cause acne dysbiosis. Garlic was aging with 3 variations of time (7, 14, and 21 days) then macerated with 70% alcohol and tested for antimicrobial activity to Cutibacterium acnes and Staphylococcus epidermidis with clindamycin as positive control. Black garlic extract provided inhibitory activity against Staphylococcus epidermidis and Cutibacterium acnes. The best recommendation time for aging garlic to prevent skin dysbiosis causes acne is 7 to 14 days.

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Fitriana, Nurul Fatwati. "GAMBARAN PENGETAHUAN IBU TENTANG PERTOLONGAN PERTAMA KEGAWATDARURATAN DEMAN PADA BALITA DI POSYANDU SOKARAJA KULON." PREPOTIF : Jurnal Kesehatan Masyarakat 5, no. 2 (October 12, 2021): 821–27. http://dx.doi.org/10.31004/prepotif.v5i2.2163.

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Fever is when the body temperature rises by 38 celcius degree. Fever in children is one of the reasons parents seek medical help to treat it. Fever management is very important to reduce the negative impact caused by fever. The aims of this studi was to determine the description of parental knowledge in first aid for fever emergencies in children. This research was a descriptive study and using cross sectional approach. Sampling was done by accidental sampling and data collection using a knowledge questionnaire of fever management with 16 questions. It was analysed by univariate analysis. Out of 20 respondent, the average value of the respondent’s knowledge was 12,25, with minimum score of 8 and maximum value of 16. The result of this research shows that all respondents would measure a chlid’s temperature using a thermometer when he had a fever, take his child to seek medical help when he was sick, and do a compress with warm water on a child who has fever.

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Mulyasari, ,., Feri Kurniawati, and Mia Setiawati. "Digestibility of pre-treated cassava peel as feed ingredient for Nile tilapia." Jurnal Akuakultur Indonesia 12, no. 2 (May 12, 2015): 178. http://dx.doi.org/10.19027/jai.12.178-185.

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ABSTRACT This research aimed at determining digestibility coefficient of cassava peel(Manihot utilissima) after immersion in 3% (w/v) NaOH for three days, fermentation using combined fungi of 10% Trichoderma viride and Phanerochaete chrysosporium for seven days, and fermentation using 15% (w/w) Bacillus megaterium for five days as feed ingredients for Nile tilapia Oreochromis niloticus. Total digestibility test was conducted by mixing 30% of cassava peel and 70% of reference diet. Nile tilapia at the average weight of 16.6 g were used as experimental fish. Fish was held for 28 days in aquarium (50x50x50 cm3) at the density of 10 fish/aquarium. Fish were fed twice daily to satiation. Feces collection started after five days of adaptation to chromium oxide diets. The results showed that the three treatments had significant effects compared to control (P<0.05), protein digestibility of were improved 5%, 15%, and 10%, energy digestibilitiy were 20%, 18%, 16%, and total digestibility of test cassava peel were 174%, 151%, and 164%, respectively. Cassava peel fermented with combined 10% mold showed the highest protein digestibility impliying it potency as feed ingredient for Nile tilapia diet. Keywords: Nile tilapia, cassava peel, NaOH, mold, bacteria, digestibility ABSTRAK Penelitian ini bertujuan untuk mengevaluasi kecernaan kulit ubi kayu (Manihot utilissima) setelah perendaman dengan NaOH 3% (w/v) selama tiga hari, fermentasi kapang Trichoderma viride dan Phanerochaete chrysosporium 10% (w/w) selama tujuh hari, dan fermentasi bakteri Bacillus megaterium 15% (w/w) selama lima hari sebagai bahan baku pakan ikan nila. Uji kecernaan total bahan dilakukan dengan mencampurkan 30% kulit ubi kayu dengan 70% pakan acuan. Ikan uji yang digunakan adalah ikan nila dengan bobot rata-rata 16,6 g. Ikan dipelihara selama 28 hari dengan kepadatan 10 ekor/akuarium berukuran 50x50x50 cm3. Pemberian pakan dilakukan dua kali sehari secara at satiation. Pengumpulan feses dimulai setelah lima hari adaptasi pakan uji yang diberi indikator kromium oksida. Hasil penelitian menunjukkan bahwa ketiga perlakuan memberikan pengaruh yang berbeda nyata terhadap kontrol (P<0,05) dan meningkatkan nilai kecernaan protein pakan berturut-turut sebesar 5%, 15%, dan 10%, nilai kecernaan energi sebesar 20%, 18%, dan 16%, serta nilai kecernaan total bahan sebesar 174%, 151%, dan 164%. Perlakuan kulit ubi kayu yang difermentasi dengan kapang menunjukkan nilai kecernaan protein pakan yang tertinggi sehingga berpotensi sebagai bahan baku pakan ikan nila. Kata kunci: ikan nila, kulit ubi kayu, NaOH, kapang, bakteri, kecernaan

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Chandra, Fioni, and I. Nyoman Ehrich Lister. "UJI AKTIVITAS ANTIFUNGAL EKSTRAK KULIT PISANG BARANGAN (MUSA ACUMINATA COLLA.) TERHADAP PERTUMBUHAN JAMUR PITYROSPORUM OVALE." BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) 6, no. 1 (May 21, 2019): 32. http://dx.doi.org/10.31289/biolink.v6i1.2211.

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Clean and Healthy Lifestyle is essential to be endeavored by society for preventing variety of infectious diseases which one of the most common is dandruff or seborrhea sicca that caused by the growth of Pityrosporum ovale fungi. This research is indicated to provide a better alternative option using ingredient given by nature that can treat dandruff. This research using banana peel extract since it is an original fruit from North Sumatra. The result from phytochemical screening of the banana peel extract shows secondary metabolites which are saponin, tannin, steroid/tritepenoida, flavonoid and glycosides. To produce barangan banana peel extract is by maseration method. Antifungal activity test using barangan banana peel extract towards Pityrosporum ovale is done by disc diffusion method. The antifungal activity test shows the biggest result for Minimum Inhibitory Concentration (MIC) extraction concentration at 1000 mg/ml with the average diameter of 11,9 mm. According to the inhibitory scale of antifungal activity test of barangan banana peel extract towards the growth of Pityrosporum ovale is ineffective.

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Barus, Bunga Rimta, Delisma Marsauli Simorangkir, Linta Meliala, and Anggun Syahfitri. "PENYULUHAN TENTANG KULIT BATANG SALAM SEBAGAI OBAT ANTIDIARE DI PUSKESMAS PATUMBAK." Jurnal Pengabdian Masyarakat Putri Hijau 2, no. 2 (March 31, 2022): 44–48. http://dx.doi.org/10.36656/jpmph.v2i2.823.

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Counseling on the efficacy of the bark of salam which aims to provide benefits about healing diarrhea at the Patumbak Public Health Center in one of the Deli Serdang districts aimed at children aged 6-17 years, by applying promotive and preventive nature through planning, mobilization, implementation, monitoring , control and appraisal. Counseling on the efficacy of the bark of salam at the Public Health Center of Patumbak, Deli Serdang Regency is aimed at increasing understanding to children aged 6-17 years, as well as parents who accompany their children, so that they can identify the symptoms of diarrhea, so that it can prevent or treat it, and malaise. - children and their parents can know the importance of monitoring their children's diet, which is healthy, which parents must take care of. Counseling will be carried out in a lecture style with conditions with discussion and brain storming that stimulates the counseling atmosphere. The evaluation of the activities was assessed from the support of the Patumbak Health Center, the timeliness of implementation, the facilities used, the number of participants who attended the counseling and the participation of the participants. Counseling participants were invited to express opinions, especially the problems faced at the Patumbak Health Center regarding anti-diarrhea so that solutions could be sought together. The results obtained from children and their parents after receiving counseling can understand well the benefits of counseling from the Patumbak Public Health Center regarding the use of the benefits of bay bark for healing. knowledge of the importance of health for their children, Families are willing to provide education and enthusiasm about the importance of the benefits of using bay bark, Parents of children and children aged 6-17 years after receiving counseling can understand well the benefits of counseling from the Patumbak Public Health Center regarding the utilization of the efficacy of the bark of salam for antidiarrheal disease in children aged 6-17 years, which has been described in their minds as just eating delicious food but not necessarily healthy for the body for all children. However, after following the counseling, children – children aged 6-17 years d can understand more fully the benefits of counseling. Community Health Center cadres, who have been providing services to children only in moderation, can change well by providing innovative promotions.

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Yumita, Yumita, Abdul Rahman Razak, Indriani, and Syaiful Bahri. "ANALISIS KLT BIOAUTOGRAFI EKSTRAK KULIT BATANG TANAMAN KAYU JAWA (Lannea coromandelica) TERHADAP BAKTERI Staphylococcus aureus DAN Shigella dysentriae." KOVALEN: Jurnal Riset Kimia 5, no. 2 (August 31, 2019): 191–96. http://dx.doi.org/10.22487/kovalen.2019.v5.i2.12786.

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Java wood plants (Lannea coromandelica) is a traditional medicinal plant which is still often used by people to treat internal and external wounds. The study aims to determine the effect of solvent polarity in Javanese stem bark extract on Staphylococcus aureus and Shigella dysenteriae, and to identify the compound groups which had an antibacterial activity against Staphylococcus aureus and Shigella dysenteriae with KLT-Bioautography analysis. The results show that the n-hexane extract of Javanese bark is not showing an antibacterial activity against Staphylococcus aureus and Shigella dysenteriae, whereas the ethyl acetate extract and methanol of Javanese bark show an antibacterial activity against Staphylococcus aureus and Shigella dysenteriae. The results of the TLC-Bioautography test show negative results for Staphylococcus aureus and Shigella dysenteriae. Keywords: Lannea coromandelica, antibacterial, Staphylococcus aureus, Shigella dysentriae, KLT-Bioautografi

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Rahma, Talitha Cresentia, and Dyan Fitri Nugraha. "Uji Aktivitas Antibakteri Ekstrak Etanol Kulit Kayu Laban (Vitex pubescens Vahl) terhadap bakteri Escherichia coli." Journal Pharmaceutical Care and Sciences 1, no. 1 (June 30, 2021): 94–101. http://dx.doi.org/10.33859/jpcs.v1i1.36.

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Background: In the world, 800.000 children die every year due to diarrheal diseases. Chronic diarrhea is usually caused by a bacterial infection, one of which is E. coli. Empirically, Dayaknese in Sampit, Central Kalimantan consuming Laban bark to treat diarrhea and dysentery. Through this research, people get scientific information about Laban wood as an alternative herbal medicine for treating diarrhea. Objective: To find out whether Laban bark can inhibit Escherichia coli bacteria and to determine the minimum inhibitory concentration in Laban bark extract that can inhibit Escherichia coli bacteria. Methods: This type of research used true experimental design with research post test only control group design. The research subjects were Escherichia coli cultured on Muller Hinton Agar (MHA) media and Laban bark extract with 3 different concentrations using the disc diffusion method. This study had 2 control groups and 3 treatment groups, DMSO as negative control, ciprofloxacin as positive control and ethanol extract of Laban bark with concentrations of 25%, 50%, and 75%. Inhibition zone diameter results were analyzed quantitatively in 3 replications. Results: The results showed that the concentrations of 25%, 50% and 75% of the extract had bacterial inhibition, in the very strong antibacterial category. Conclusion: The ethanol extract of Laban bark can inhibit the growth of Escherichia coli with an minimun inhibitory concentration 25%, which is in the very strong inhibition category. Keywords: Disc diffusion, Escherichia coli, Laban bark (Vitex pubescens Vahl)

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Siregar, Ike G., Daniel Lantang, and Linus Y. Chrystomo. "Analisis Golongan Metabolit Sekunder Ekstrak Etanol Kulit Batang Cemara Laut (Casuarina equisetifolia L.) dan Cemara Gunung (Casuarina junghuhniana Mig.)." JURNAL BIOLOGI PAPUA 14, no. 2 (October 15, 2022): 143–49. http://dx.doi.org/10.31957/jbp.1687.

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The use of medicinal plants as natural medicine is increasingly trend and developing rapidly to prevent and treat disease, also maintain human health. Spruce plants belong to Casuarinaceae family and Magnoliophyta, generally contain of secondary metabolite compounds such as: alkaloid, saponin, polyphenol, flavonoid, and tannin that can be efficacious to cure diseases in human. The purpose of this study was to analyze the secondary metabolites compound of Casuarina equisetifolia L. and Casuarina junghuhniana Mig. using the Fransworth phytochemical screening method of bark ethanol extracts. The analysis of phytochemical screening of spruce bark shows flavonoid, saponin and tannin activity, while the montain spruce shows alkaloid, steroid, saponin and tannin activity. Further research is needed to investigate the ethnopharmaceutical information on the use of the spruce plants as a traditional medicine.Key words: Spruce plants; screening; extract; analysis; phytochemical; secondary metabolite

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Rollando, Rollando, and Rokiy Alfanaar. "ISOLASI SENYAWA TURUNAN NAPTOKUINON DARI KULIT BATANG FALOAK (Sterculia quadrifida R.BR) DAN UJI AKTIVITAS ANTIKANKER PADA SEL KANKER PAYUDARA JENIS T47D." CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) 5, no. 1 (July 28, 2017): 12. http://dx.doi.org/10.24843/ck.2017.v05.i01.p02.

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ABSTRAK: Faloak (Sterculia quadrifida R.Br) digunakan secara empiris oleh penduduk Nusa Tenggara Timur untuk mengobati hepatitis, tifus, maag, dan pemulih stamina. Informasi senyawa aktif yang terkandung didalam kulit faloak secara spesifik belum dipublikasi. Penelitian ini bertujuan untuk mengetahui senyawa aktif yang terdapat didalam kulit faloak sebagai antikanker. Ekstraksi menggunakan metode maserasi, isolasi menggunakan metode isolasi bertingkat, elusidasi menggunakan penggabungan informasi dari spektra IR, 1D-NMR, 2D-NMR dan LC-MS, dan uji aktivitas antikanker pada sel kanker payudara T47D menggunakan metode MTT. Hasil isolasi diperoleh isolat turunan senyawa naptokuinon yaitu 2,3-dihydro-6-hydroxy-2-methylenenaphtho[1,2-b]furan-4,5-dione yang aktif sebagai antikanker dengan nilai IC50 pada sel kanker payudara sebesar 9,88 µg/mL dan dengan nilai selektivitas indeks sebesar 30,23. ABSTRACT: Faloak (Sterculia quadrifida R.Br) is used empirically by residents of East Nusa Tenggara to treat hepatitis, typhoid, ulcers, and stamina restorers. The information of the active compounds contained in the faloak skin is not specifically published. This study aims to determine the active compounds contained in the bark of faloak as anticancer. The extraction was conducted with maceration method followed by a multilevel isolation method. The elucidation was carried out using information of IR spectra, 1D-NMR, 2D-NMR and LC-MS. The anticancer activity test on T47D breast cancer cells was also conducted using MTT method. Based on the results obtained, the active compound is naphthoquinone derivative compound which is 2,3-dihydro-6-hydroxy-2-methylenenaphtho [1,2-b] furan-4,5-dione that has anticancer activity on breast cancer cell (T47D) with IC50 value of 9.88 µg/mL and index selectivity value of 30.23.

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Wahid, Rahmat A. Hi. "Pengaruh Polivinilpirolidon sebagai Polimer Mukoadhesif terhadap Sifat Fisik Patch Ekstrak Kulit Buah Delima (Punica granatum L.)." Lumbung Farmasi: Jurnal Ilmu Kefarmasian 1, no. 2 (August 14, 2020): 85. http://dx.doi.org/10.31764/lf.v1i2.2727.

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ABSTRAKBuah delima (Punica granatum L.) secara empiris digunakan untuk mengobati masalah gigi dan mulut seperti sariawan. Pengembangan obat sariawan berbasis herbal dengan bentuk sediaan patch dilakukan untuk mempertahankan waktu kontak antara zat aktif dengan bagian sariawan. Polivinilpirolidon (PVP) digunakan sebagai polimer karena sifatnya mukoadhesif sehingga mampu berikatan pada mukosa mulut. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan PVP sebagai polimer mukoadhesif terhadap karakteristik fisik sediaan patch yang mengandung ekstrak kulit buah delima (EKBD). EKBD diperoleh dengan metode maserasi. Konsentrasi EKBD yang digunakan adalah 5% dan 10%. Sedangkan konsentrasi polimer PVP yang digunakan yaitu 30,29%, 33,04, 48,75%, dan 65,5%. Patch selanjutnya akan di evaluasi fisik yang meliputi keseragaman bobot dan dimensi ketebalan, pH permukaan, swelling, daya lekat, dan waktu lekat. Hasil menunjukkan bahwa patch yang mengandung ekstrak 10% dengan tambahan polimer konsentrasi 30,29% memiliki sifat yang cukup elastis disbanding dengan konsentrasi 48,75% dan 65,5%. Sedangkan uji evaluasi fisik menghasilkan keseragaman bobot dan dimensi yang seragam, pH 6,63, rata-rata indeks swelling 40,69% ± 16, dan rata-rata daya dan waktu lekat 13,50 ± 11,6. Dengan demikian dapat disimpulkan bahwa konsentrasi PVP terbukti berpengaruh pada sifat fisik patch yang dihasilkan. Kata kunci : Polivinilpirolidon; Ekstrak Kulit Buah Delima; Patch.ABSTRACTPomegranate (Punica granatum L.) is empirically used to treat dental and mouth problems such as reccurent aphthous stomatitis (RAS). The development of RAS therapy based on herbal with patches dosage forms is carried out to maintain the contact time between the active substance and the RAS. Polyvinylpyrrolidone (PVP) is used as a polymer because it is mucoadhesive, so it can bind to the oral mucosa. Aimed to determine the effect of the use of PVP as a mucoadhesive polymer on the physical characteristics of patches preparations containing pomegranate peel extract (PPE). PPE was obtained by maceration method. The PPE concentration used were 5% and 10%. PVP concentration used were 30.29%, 33.04%, 48.75%, and 65.5%. The patches properties such as uniformity of thickness, pH, swelling index, tensile and mucoadhesive strength. The results showed that patches containing 10% extract and PVP concentration of 30.29% had sufficient elastic properties compared to both concentration. While the physical evaluation test obtained uniform weights and dimensions that are uniform, pH 6.63, the average swelling index is 40.69% ± 16, and the tensile and mucoadhesive strength is 13.50 ± 11.6. Altogether, the concentration of PVP is proven to affect the physical properties of the resulting patch.Key word : Polyvinylpyrrolidone; Pomegranate Peel Extract; Patch.

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Karta, I. Wayan, Putu Annand Kurnia Iswari, and Luh Ayu Nanamy Khrisnashanti Eva Susila. "TEH CANG SALAK : TEH DARI LIMBAH KULIT SALAK DAN KAYU SECANG YANG BERPOTENSI UNTUK PENCEGAHAN DAN PENGOBATAN PENYAKIT DEGENERATIF." Meditory : The Journal of Medical Laboratory 7, no. 1 (July 7, 2019): 27–36. http://dx.doi.org/10.33992/m.v7i1.473.

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This study aims to treat salacca peel and secang wood waste into herbal tea and analyze the phytochemical content and antioxidant capacity and organoleptic test of the products made. Salak skin waste samples were taken at the salak center in Sibetan Village and secang wood obtained in Tenganan Village, Karangasem. Antioxidant capacity testing was carried out in the Laboratory Service Unit of the Faculty of Agricultural Technology at UNUD, and phytochemical tests at the Health Polytechnic Department of Denpasar. Organoleptic tests were carried out on 20 panelists. Tea is made by mixing secang wood powder which has been mashed with salak skin powder using 3 variations, namely VR1 (1.5 gram: 0.5 gram), VR2 (1gram: 1 gram), VR3 (0.5 gram: 1.5 gram) ), then soaked in hot water and analyzed.The results showed that Cang Salak Tea with variations of VR1, VR2, and VR3 has active phytochemical content of flavonoids, tannins, alkaloids, terpenoids, and phenols. These compounds have the potential for degenerative diseases. Antioxidant capacity in VR1, VR2, and VR3 are 343.88; 183.88, and 92.12 mg / L GAEAC. The difference in content is caused by the presence of antioxidants in higher secang wood compared to bark. The tea has the potential to be developed into an antioxidant drink which is useful for the prevention and control of degenerative diseases. Organoleptic tests showed that Cang Salak tea products with various variations were favored by panelists. The most preferred color is in VR1, the aroma is on VR3, and it feels on VR2. Future studies require strength tests of antioxidant activity and in vitro or in vivo testing of Cang Salak tea for degenerative diseases

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Handayani, Fitri, Eka Siswanto, and Lintang Ayu Trisna Pangesti. "UJI AKTIVITAS EKSTRAK ETANOL GAMBIR (Uncaria gambir Roxb.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA KULIT PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus)." Jurnal Ilmiah Manuntung 1, no. 2 (January 26, 2017): 133. http://dx.doi.org/10.51352/jim.v1i2.25.

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Gambir (Uncaria gambir Roxb.) contains flavonoids, tannins, saponins and alkaloids that can help in the healing process of burns on the back skin of mice. Gambir has been used for the treatment because it has the effect of antimicrobial and anti-inflammatory. Gambir is used by the people as a traditional medicine to treat burns.This research is experimental research. The object studied is the potential of gambir extract on healing burns of mice back skin. The number of mice used are 15 which divided into 5 groups: the positive control group (branded ointment), negative control group (vaseline flavum), group of gambir ethanol extract and vaseline flavum concentration of 25%, 35%, and 45%. Each group consisted of 3 mice.Backs of the mice induced using a heated solder which tip contained stainlees plate measuring 1x1 cm and placed for 2 seconds on the back skin of mice. The percentage of burns healing is obtained by calculating the surface area of the wound. The data were analyzed using ANOVA analysis followed by LSD test. The results showed that ethanol extract of gambir concentration of 25% with the healing burns percentage of (72.00%), the concentration of 35% (85.00%), and the concentration of 45% (88.67%) have activity on healing burns of back skin of mice. The results of data analysis using ANOVA showed that the data has significant differences with a significance value <0.05 is 0.000. LSD test results stated that each treatment group have significant differences with a significance value <0.05. It can be seen that with increasing dose will be followed by duration of burns healing

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Yanti, Leni Nurlina, Anny Victor Purba, and Ratna Djamil. "Pengembangan Sediaan Krim Pencerah Kulit dari Kombinasi Ekstrak Rimpang Temulawak (Curcuma Xanthorrhiza Roxb) dan Ekstrak Biji Kacang Kedelai (Gl ycine Max (L.) Merill)." Buletin Penelitian Kesehatan 47, no. 1 (June 19, 2019): 55–66. http://dx.doi.org/10.22435/bpk.v47i1.1385.

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Javanese turmeric (Curcuma xanthorrhiza) and soybean (Glycine max L. Merill) are natural ingredientsthat can be used to treat face skin. The aim of this study was to formulate extracts of Javanese turmeric andsoybean in the form of skin lightening cream preparations.. In this experiment, four cream formulationswere made containing a combination of javanese tumeric extract with concentrations of 1%, 3%, 5% and10% and soybean extract with concentrations of 5% and 15%. Accelerated cream formulations stabilitytest for 1 month was tested by observing the results of its storage at low temperatures, room temperatureand high temperature which included organoleptic observation, pH and homogeneity where each formulashowed physical stability for 4 weeks, pH average 4.5-5.0, and no change in cream color. The irritationtest was tested by using the acute dermal irritation method using rabbits and was declared safe and notirritating. The effectiveness test was measured by applying a combination cream to the respondents andmeasuring the brightness of the skin using a Dermalab examination measured after using the cream.The combination cream with a variation of 10% javanese tumeric concentration and 15% soybeanconcentration was the highest L* score in lightening the skin. Key words: Curcuma rhizome extract; soybean seed extract; cream;skin lingkening

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Handayani, Tien Wahyu, Agustinus Widodo, Risna Yanti, Erdy Prasetyo, Zulfaidah, and Joni Tandi. "Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus)." KOVALEN: Jurnal Riset Kimia 7, no. 3 (December 30, 2021): 161–68. http://dx.doi.org/10.22487/kovalen.2021.v7.i3.15567.

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The snake fruit peel (Salacca zalacca (Gaertn.) Voss) traditionally has several health benefits, one of which is to treat diabetes mellitus. This study aimed to determine the content of secondary metabolites in the ethanolic extract of snake fruit peel and its activity on glucose and urea creatinine levels in male white rats (Rattus norvegicus). Phytochemical screening of extracts was carried out qualitatively and quantitatively using UV-Vis Spectrophotometry. This study is a laboratory experimental study using 30 test animals divided into 6 treatment groups (normal control, negative control, positive control, 70 mg/kg BW, 140 mg/kg BW, and 280 mg/kg BW). The results showed that the ethanol extract of the bark of the salak fruit contained 7.61 %w/w alkaloids, flavonoids 0.041% w/w, tannins 1.18% w/w, and saponins 2% w/w. Ethanol extract of salak fruit peel dose of 140 mg/kg BW affected decreasing blood glucose and urea creatinine levels. The skin of the salak fruit has the potential to be further investigated as an antidiabetic.

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Dudayev, Rayhan. "TINDAKAN AFIRMATIF SEBAGAI BENTUK KEADILAN PADA PENEGAKAN HUKUM LINGKUNGAN HIDUP DI LAUT : STUDI KASUS MV HAI FA DAN NELAYAN UJUNG KULON." Jurnal Hukum Lingkungan Indonesia 2, no. 1 (March 4, 2020): 48. http://dx.doi.org/10.38011/jhli.v2i1.20.

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AbstrakUpaya penegakan hukum yang tegas merupakan salah satu cara untuk menjaga kelestarian lingkungan. Instrumen hukum lingkungan dibuat dan ditegakkan untuk mencegah terjadinya kerusakan lingkungan. Namun pada pelaksanaannya, penegakan hukum lingkungan tidak senada dengan konsep pembangunan berkelanjutan. Penegakan hukum lingkungan seolah hanya tajam ke bawah namun tumpul ke atas. Dalam tulisan ini, akan dibahas mengenai penegakan hukum lingkungan di sektor maritim dalam dua kasus yang berbeda, berkaitan dengan pelanggaran Undang-Undang Konservasi Nomor 5 Tahun 1990 Tentang Koservasi Sumber Daya Alam dan Ekosistemnya. Perbedaan sebab akibat dalam kasus yang berbeda tidak membuat hukum memperlakukan kedua kasus tersebut secara berbeda karena adanya asas kesamaan (equality before the law) dalam hukum. Tulisan ini akan memaparkan penegakan hukum, terutama hukum pidana, ditinjau dengan perspektif pembangunan berkelanjutan pada kasus nelayan dan kasus illegal fishing yang melibatkan korporasi. Berangkat dari perspektif tersebut, tulisan ini mencoba menganalisis alasan pentingnya tindakan afirmatif bagi penegakan hukum di masing-masing kasus. AbstractOne of the means to protect the environment is to firmly enforce the environmental law. Environmental legal instruments are made and enforced in order to prevent environmental damage. However, environmental law enforcement in practice is not always consistent with the concept of sustainable development. Environmental enforcement is sharper to the poor people, but dull to big corporations. This article attempts to discuss the enforcement of environmental law in the maritime sector in two different cases, with regard to the violation of Law no. 5 of 1990 regarding Conservation. Despite the different causation and magnitude of impacts, the law treats those cases equally due to the equality before the law principle. This article also elaborates the law enforcement, especially criminal law, with the perspective of sustainable development in the case of involving fishermen and the illegal fishing case involving a corporation. From this perspective, this paper analyzes the importance affirmative action for the law enforcement in each case.

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Cahyawati, Putu Nita. "EFEK FARMAKOLOGI DAN TOKSIK SIRSAK (Annona muricata): A MINI-REVIEW." Biomedika 12, no. 2 (August 30, 2020): 107–16. http://dx.doi.org/10.23917/biomedika.v12i2.10691.

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ABSTRAKAnnona muricata (sirsak) telah digunakan secara tradisional sejak lama untuk mengatasi demam, nyeri, gangguan pernapasan dan kulit, sebagai antiparasit, mengatasi infeksi bakteri, menurunkan tekanan darah, mengatasi peradangan, mengatasi diabetes dan kanker. Oleh karenanya, banyak studi baik in vitro maupun in vivo ditujukan untuk membuktikan manfaat tersebut. Senyawa kimia telah berhasil diisolasi dari tanaman ini diantaranya: alkaloid, fenol, dan asetogenin. Senyawa-senyawa tersebut diyakini berperan terhadap efek farmakologi pada berbagai kondisi penyakit. Walaupun demikian, keamanan atau toksisitas tanaman ini masih dipertanyakan baik untuk pemakaian jangka pendek maupun jangka panjang. Dosis efektif tanaman ini juga belum diketahui secara pasti. Melalui tulisan ini, penulis hendak merangkum berbagai efek farmakologi serta efek toksik yang dapat ditimbulkan oleh Annona muricata berdasarkan hasil penelitian terdahulu.Kata Kunci: Annona Muricata, Sirsak, Efek Farmakologi, Efek ToksikABSTRACTAnnona muricata (sirsak) has been used traditionally for a long time to treated fever, pain, respiratory and skin disorders, as an antiparasitic, to treat bacterial infections, reduce blood pressure, to treat inflammation, diabetes and cancer. Therefore, many studies both in vitro and in vivo were aimed to prove these benefits. Various chemical compounds have been successfully isolated from these plants. These compounds were believed to play a vital role in pharmacological effects in various diseases. Nevertheless, the safety or toxicity of this plant was still questionable for both short and long term use. The effective dose of this plant was also not known with certainty. Through this paper, the author wishes to summarize the various pharmacological and toxic effects that can be caused by Annona muricata based on the results of previous studies.Keywords: Annona Muricata, Soursop, Pharmacological Effects, Toxic Effects

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Taniowas, Paul O., Tara S. Kairupan, Marlyn G. Kapantow, and Aryani Adji. "Bullous Pemphigoid in a Women with Type 2 Diabetes Mellitus: A Case Report." e-CliniC 10, no. 1 (March 22, 2022): 131. http://dx.doi.org/10.35790/ecl.v10i1.39085.

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Abstract: Bullous Pemphigoid (BP) is an autoimmune disease with subepidermal blisters that are generally minimally itchy to non-itchy. It usually occurs in old age, but sometimes in children and young adults. Clinical presentation shows large, tense-walled blisters on normal or erythematous skin, mostly at the folds, lower abdomen, thighs, but they can appear anywhere. Therapy of BP is aimed to treat skin and mucous lesions as soon as possible and to reduce itchiness, therefore, the quality of life will be improved. The first line therapy is oral and topical corticosteroids, with an initial dose of prednisone 0,75-1mg/kg/day or less. Prednisone tapering should be carried out in accordance with the clinical response and side effects. We reported a 47-year-old female, complained blisters on chest, abdomen, both arms and legs simultaneously. History of uncontrolled diabetes mellitus was present. Skin biopsy revealed subepidermal bullae associated with infiltraton of inflammatory cells, and Nikolsky sign and Asboe-Hansen sign showed negative results. Based on the results, the patient was diagnosed as BP. Prednisone was given 40mg/day with weekly tapering. After two weeks of prednison therapy, the lesions showed great improvement. After six weeks of therapy, the blister formation stopped, and a gradual tapering-off of the corticosteroid dose was recommended according to clinical responses until three months of therapy. The blisters reduced without any side effects. In this case, prednisone showed good result, and complete resolution occurred after six weeks of therapy.Keyword: bullous pemphigoid; diabetes mellitus; prednisone Abstrak: Pemfigoid Bulosa (PB) merupakan penyakit autoimun dengan lepuh subepidermal yang umumnya gatal minimal hingga tidak gatal, lebih sering terjadi pada usia tua, kadang pada anak dan dewasa. Gambaran klinis berupa lepuh besar, dinding tegang di atas kulit normal atau dasar eritematosa. Biasanya ditemukan di lipatan, perut, paha, tetapi bisa muncul di mana saja. Terapi PB bertujuan untuk menyembuhkan lesi kulit dan mukosa dengan cepat dan mengurangi rasa gatal untuk meningkatkan kualitas hidup. Penggunaan kortikosteroid oral dan topikal merupakan lini pertama, dengan dosis awal prednison 0,75-1mg/kg/hari atau kurang. Tapering prednison harus dilakukan sesuai dengan respon klinis dan efek samping. Kami melaporkan kasus seorang wanita, 47 tahun, dengan keluhan lepuh-lepuh di dada, perut, kedua lengan dan kaki muncul bersamaan dengan riwayat diabetes melitus tidak terkontrol. Biopsi kulit dilakukan dengan hasil bula subepidermal disertai infiltrasi sel inflamasi. Nikolsky sign dan Asboe-Hansen sign memberikan hasil negatif. Pasien didiagnosis sebagai PB dan diberikan prednison 40 mg per hari dengan tapering per minggu. Setelah dua minggu terapi prednison, lesi menunjukkan banyak perbaikan. Setelah enam minggu terapi, pembentukan lepuh terhenti, dan dilakukan pengurangan dosis prednison secara bertahap sesuai respons klinis sampai tiga bulan terapi. Lepuh berkurang tanpa efek samping. Pada kasus ini, prednison memberikan hasil yang memuaskan, dan resolusi lengkap tercapai setelah enam minggu terapi.Kata kunci: pemfigoid bulosa; diabetes mellitus; prednison

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Sinyakova, Lyudmila N. "Communication Failure in A. P. Chekhov’s Poetics: Architectonic Factor (A Nightmare, Enemies, An Awkward Business)." Vestnik NSU. Series: History and Philology 19, no. 2 (2020): 90–98. http://dx.doi.org/10.25205/1818-7919-2020-19-2-90-98.

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Purpose. The article examines communication failure which is one of the major factor of Chekhov’s poetics. The problem of architectonics is based on dialogue principle in narrative and values unity. Results. A Nightmare is a story of social misunderstanding. A public character Kunin treats a country priest father Yakov as a hard-drinking person. He is highly snobbish and refuses to hear the poor priest. Finally, his revelation of someone’s else being, except his own, shakes him much. But his newly gained knowledge about social issues such as destitution is not deep. Later, Kunin calms down and ruminates over his lack of money to help father Yakov and the other poor person, the doctor. The author’s conclusion discredits his attempt to become a better person. Overall, the dialogue of positions is just quasi-communication. In his next work, Enemies, Chekhov’s poetic construction appears to be more complicated. Doctor Kirilov and Abogin, a rich man, both experience grief, but the reasons for their grief are entirely different. Doctor has lost his only little son an hour before, but Abogin compels him to save his wife. When they arrive to Abogin’s country-estate, it turns out that the woman has just run away with her lover. This farce provokes the doctor’s rage. He blames Abogin, saying that the rich man’s distress is empty and ridiculous. According to the author, the offended Kirilov can hardly be considered wrong. And once again, the author’s conclusion sums up the short story. An existential connotation manifests the communication breakdown. The third short story, An Awkward Business, is devoted to problem of total communication failure. The main character, doctor Ovchinnikov, is not heard at all. His business matter turns out to be a matter of further existence, but nobody wants to understand the essence of his trouble. Finally, his case is interpreted in a formal way and is not solved. The author simply lets things go on, standing outside the text. And this is the innovative feature of Chekov’s mature creative work. Conclusion. To sum up, in three Chekhov’s short stories communication failure is an important factor of poetics, which is developed in his later works.

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Trisnowati, Dwi M., Hyacintha P. Budi, Shienty Gaspersz, and Meilany Durry. "Bullous Pemphigoid Treated with Corticosteroid: A Case Report." e-CliniC 10, no. 2 (September 27, 2022): 400. http://dx.doi.org/10.35790/ecl.v10i2.41403.

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Abstract: Bullous pemphigoid (BP) is an autoimmune disease clinically characterized by pruritic, large, tense subepidermal bullae over normal skin, erythematous or urticarial plaques. The pathogenesis related to the immune system towards BP antigen 180 and 230. Mild lesions may be treated with topical corticosteroid but the more extensive lesions are treated with oral corticosteroids. We reported a case of 58-year-old man came with clear fluid-filled blisters on the body since a week ago. Dermatological examination revealed multiple vesicle-bullae, filled with clear fluid, tense walls. Nikolsky sign and Asboe-Hansen sign were negative. Histopathological examination supported the diagnosis of BP. Diagnosis was established based on anamnesis, and physical and histopathological examinations. The patient was treated with systemic corticosteroid due to the consideration of the extensive lesions. Methylprednisolon was given intravenously at a dose of 43.75 mg per day which was then replaced orally for tapering off. The dose reduction of 4 mg per week was carried out according to the clinical improvement. In conclusion, this case improved after being treated with systemic corticosteroid for approximately 2-3 months.Keywords: bullous pemphigoid; corticosteroid Abstrak: Pemfigoid bulosa (PB) merupakan penyakit bula autoimun ditandai dengan pruritus dan bula subepidermal besar berdinding tegang di atas kulit yang normal, eritematosa atau plak urtikaria. Patogenesisnya berhubungan dengan sistem kekebalan tubuh yaitu respons imun terhadap antigen BP 180 dan 230. Penatalaksanaan untuk lesi ringan diberikan kortikosteroid topikal, sedangkan untuk lesi luas dengan kortikosteroid sistemik. Kami melaporkan seorang laki-laki berusia 58 tahun dengan keluhan lepuh-lepuh berisi cairan jernih pada hampir seluruh tubuh sejak satu minggu lalu. Pada pemeriksaan fisik ditemukan vesikel-bula, multipel, berisi cairan jernih, dinding tegang. Pemeriksaan tanda Nikolsky dan Asboe-Hansen negatif. Pemeriksaan histopatologik mendukung diagnosis PB. Tatalaksana yang diberikan berupa kortikosteroid sistemik karena pertimbangan lesinya yang luas. Metilprednisolon diberikan secara intravena dengan dosis 43,75 mg per hari yang kemudian diganti pemberian per oral saat tapering off. Penurunan dosis 4 mg metilprednisolon per minggu dilakukan sesuai dengan perbaikan kondisi klinis. Simpulan kasus ini ialah pemfigoid bulosa yang mengalami perbaikan setelah diterapi dengan kortikosteroid sistemik selama kurang lebih 2-3 bulan.Kata kunci: pemfigoid bulosa; kortikosteroid

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Puspaningtyas, Anggraeny, Tri Pramesti, Ingesti Lady Rara P., and Mita Octaviani. "MENGGAGAS DESA WISATA PLUNTURAN BERBASIS KEARIFAN LOKAL DI KABUPATEN PONOROGO JAWA TIMUR." PEDULI: Jurnal Ilmiah Pengabdian Pada Masyarakat 4, no. 2 (January 30, 2021): 59–69. http://dx.doi.org/10.37303/peduli.v4i2.210.

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Plunturan is one of villages in Ponorogo, East Java Province. The prime product of Plunturan Village is a cultural heritage that is still maintained by the local village community. The various cultural products are Reyog (Reyog Anak, Reyog Perempuan dan Reyog Taruna); Gajah-Gajahan; Jathilan; Ganongan; Tledekan; Karawitan; Wayang Kulit; Coke’an; Metik Desa; Metri Desa; Metri Tandur; Campursari; and Sego Angkruk. Artists come from across generations, passed down through village elders and art groups. Artists today do not consider the potential of art in their village as their main source of income. They have other livelihoods such as farmers, traders, civil servants, government officials, teachers, health workers, private employees. This condition causes a lack of initiative from artists to attract tourists from outside the region. The role of stakeholders in Plunturan Village is very important in developing cultural tourism. The Tourism Awareness Group (Pokdarwis) which is the driving force for cultural tourism development activities must develop a strategy to make Plunturan a tourism village. Therefore, this service uses a SWOT analysis (strengths, weaknesses, opportunities and treath) to find out what strategies should be taken to initiate Plunturan Tourism Village based on local wisdom. So that culture-based development is not only aimed at improving culture, but also in carrying out development it is necessary to base on the culture that is owned, especially regarding value systems, attitudes and customs.

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Alaydrus, Syarifah maryam, Wahyu Widayat, and Laode Rijai. "Gambaran Hasil Aktivitas Antioksidan Berberapa Perlakuan Teknik Preparasi Pembuatan Konsentrasi Ekstrak Kulit Buah Nanas (Ananas comosus L.Merr) Menggunakan Senyawa DPPH (1,1-diphenyl-2-picrylhydrazyl)." Proceeding of Mulawarman Pharmaceuticals Conferences 10 (October 31, 2019): 44–47. http://dx.doi.org/10.25026/mpc.v10i1.365.

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Pineapple skin (Ananas comosus L.Merr) has been known to have a category of strong antioxidant activity against reducing DPPH compounds (1,1-diphenyl-2-picrylhydrazyl). However, references to the preparation process of extract concentration making and the treatment of DPPH compounds to extracts are not much elaborated, so that it can cause errors in inferring the category of antioxidant activity. The purpose of this study was to determine the results of antioxidant activity through the treatment of preparation techniques for the concentration of pineapple peel extract concentration. Pineapple peel extract (Ananas comosus L. Merr) was prepared by maceration method using 70% ethanol solvent. Testing of antioxidant activity was carried out using the UV-Vis spectrophotometric method at a wavelength of 516.4 nm. The extract concentration to be tested was 500 μg/mL, 250 μg/mL, 125 μg/mL, 62.5 μg/mL and 31.25 μg/mL and the concentration of DPPH compounds (1,1-diphenyl-2-picrylhydrazyl) was 45 μg/mL. Treat the extract making concentration divided into 3 namely P1 (multilevel dilution with a volume ratio of 1: 1) P2 (normal dilution with a volume ratio of 1: 1) and P3 (DPPH solution is used to suffice the volume of the extracted test extract). The results of percent inhibitors from each treatment of making concentrations showed P1 <P2, P1 <P3, P2 <P3, and IC50 of each treatment were P1 268.07 μg/mL, P2 was 231.28 μg/mL, P3 was 78.403 μg/mL. Based on the results of IC50 P3 gives the category of antioxidant activity that is 78,403.Keywords: pineapple fruit skin (Ananas comosus L. Merr), antioxidants, dpph (1,1-diphenyl-2- picrylhydrazyl), dilution.

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Nasihah, Mimatun, and Ida Susila. "Pengobatan Penyakit Vitiligo Melalui Penggunaan Cream Biji Lada Hitam (Piper nigrum L.)." Journal of Pharmacy and Science 4, no. 1 (January 30, 2019): 45–52. http://dx.doi.org/10.53342/pharmasci.v4i1.131.

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ABSTRAKVitiligo adalah penyakit yang menyebabkan terbentuknya bercak-bercak putih pada kulit. Penyakit ini dapat terjadi pada segala usia, tapi umumnya sebelum pengidap berusia 20 tahun. Ada yang mengalami penyebaran bercak dengan cepat dan ada yang lambat. Sebagian besar penderitanya kehilangan pigmen kulit secara perlahanlahan pada hampir seluruh permukaan kulit. Selama ini pengobatan medis kurang begitu memberikan efek penyembuhan yang signifikan. Salah satu alternatifnyaadalah melaluipenggunaan bijiladahitamsebagaialternatifpengobatan herbal. Kandungan piperine yang terdapat dalam biji lada hitam ternyata membantu menstimulasi pigmentasi. Penelitian dan pengaplikasianterutama dalambidang kesehatan masih terbatas sehingga perludilakukan banyak kajian dan penelitian lebih lanjut.Dalam penelitian ini dilakukan pengujian pengobatan penyakit vitiligo menggunakan cream biji lada hitam. Produk tersebut didapatkan dari percampuran antara biji lada hitam dengan basis cream emulgade, metyl paraben dan baking soda sehingga terbentuk cream. Pengujian yang dilakukanmeliputi uji pH, Uji mikrobiologi, Uji Farmasetika dan uji Efektivitas cream lada hitam dalam mengobati penyakit vitiligo. Hasil pengujian pH diperoleh hasil bahwa cream biji lada hitam dengan perbandingan 1:1, 1:2, 1:3 dan 1:4 adalah 7 yang merupakan pH normal untuk kulit. Uji mikrobilogi didapatkan hasil jumlah mikroba pada sampel sebesar 2.5 x 103 Cfu/gram. Tingginya nilai Angka Lempeng Total tersebut masih memenuhi persyaratan cemaran mikroba oleh BPOM yakni sebesar 104. Uji Farmasetika menunjukkan bahwa pemisahan fase tidak ada,terapat partikel kasar, struktur tidak rata, warna tidak rata dan tidak homogen. Uji daya lekatnya 16.1 detik, warna coklat kehitaman, konsistensinya semi solida, bau khas lada. Sementara uji daya sebar dengan beban 1000gram dihasilkan 5.2. Uji efektivitas cream lada hitam menggunakan Uji T Paired menghasilkan T hitung sebesar 4.522 sedangkan T tabel adalah sebesar 1.74588 sehingga nilai T hitung > T tabel, artinya terdapat perbedaan signifikan luas paparan vitiligo sebelum dan sesudah diberi cream ladahitam.Kata kunci: Vitiligo, Cream, Biji Lada Hitam. ABSTRACTVitiligo is a dermatology disorder characterized by whitish patches. This condition may occurs in all ages but commonly in twenties. The patches formed may spread fast or slowly throughout the body and gradually the skin loss its pigmen. By far, the treatments of vitiligo do not showed significant benefits. One of the alternatif treatments is the usage of black pepper seeds as herbal medicine. The Piperine content of black pepper seeds believed to help pigmentation process of the skin. However, the usage of black pepper seeds as vitiligo treatments still need to be overcome.This study was aimed to evaluate the effectiveness of black pepper seeds extract cream to treat vitiligo. The cream was formulated through the mixing of black pepper seeds extract with emulgade cream basic, methyl paraben and sodium bicarbonate. The cream then was evaluated for various parameters such as pH, mycrobiology, pharmaceutics and effectivity. The result of pH evaluation showed that all of formulation ratio (1:1, 1:2, 1:3 and 1:4) of the black pepper extract cream have neutral pH which is the same as normal skin pH. The microbiology test result showed the total number of viable microorganism were 2.5 x 103 Cfu/gram which is stil under the BPOM recommendation (104 Cfu/gram). The pharmaceutics test showed that the cream has no breaking phase, contain of some rough particle, unhomogen structure and colour. The adhessiveness of the cream was last for 16.1 second, has dark brown colour, semisolid consistency, and peppery smell. The spreadibility test using 1000 gram of weight showed 5.2 scale. The effectiveness test of the cream using Paired T-test showed calculated T-value was 4.522 which is hinger than the table value 1.74588. This concluded that there was significant different of vitiligo patches before and after the usage of black pepperextract cream.Keywords: Vitiligo, Cream, Black pepper seeds.

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Pramiastuti, Oktariani, Fiqih Kartika Murti, Sri Mulyati, Ulfatun Khasanah, Rima Harsa Atqiya Alquraisi, Ainun Afifah, Aisyah Khairunisa Nitha Sundawa, Ela Nandayani, and Yoga Pamungkas. "Aktivitas Antioksidan Ekstrak Etanol Temu Blenyeh (Curcuma Purpurascens Blumae) Dengan Metode Dpph (1,1 Diphenyl-2-Picrylhydrazyl)." Prosiding Seminar Nasional Kesehatan 1 (November 8, 2021): 29–37. http://dx.doi.org/10.48144/prosiding.v1i.618.

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ABSTRACTAntioxidants have a function to scavenge and neutralize oxidation effect caused by free radicals by preventing the formation of radicals. Temu blenyeh (Curcuma purpurascens Bl) is one of the curcuma species which is still under-researched. Traditionally, temu blenyeh is used to treat stomachache, cough, itch, and skin infection. Some studies show that temu blenyeh extract had antioxidants activity and anti-cancer. The extract contains flavonoid, terpenoid, steroid, triterpenoid, essential oil. The study aimed to determine antioxidant activity of ethanol extract of temu blenyeh using DPPH method. Temu blenyeh was extracted by maceration with 96% ethanol solvent. The antioxidants activity test described that the value of IC50 was 48.697 ppm. Keywords: Temu blenyeh, DPPH, antioxidants Abstrak Antioksidan berfungsi untuk menangkal dan menetralisasi efek oksidasi yang disebabkan radikal bebas dengan cara mencegah terbentuknya radikal. Temu blenyeh (Curcuma purpurascens Bl) salah satu spesies curcuma yang masih sedikit diteliti. Temu blenyeh secara tradisional digunakan untuk mengobati sakit perut, batuk, gatal, dan infeksi kulit. Beberapa penelitian membuktikan bahwa ekstrak rimpang temu blenyeh memiliki aktivitas antioksidan dan anti kanker. Temu blenyeh mengandung flavonoid, terpenoid, steroid, triterpenoid dan minyak esensial. Penelitian ini bertujuan untuk mengetahui adanya aktivitas antioksidan pada ekstrak etanol temu blenyeh menggunakan metode DPPH. Temu blenyeh diekstraksi dengan metode maserasi menggunakan pelarut etanol 96%. Dalam penelitian uji aktivitas antioksidan ekstrak etanol temu blenyeh menunjukkan hasil nilai IC50 sebesar 48,697 ppm. Kata kunci : Temu blenyeh; DPPH; Antioksidan

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Meida, Eka, and St Rahmatullah. "Uji Aktivitas Antibakteri Formulasi Salep Ekstrak Etanol Daun Bandotan (Ageratum conyzoides L.) Terhadap Bakteri Staphylococcus aureus ATCC 25923." Prosiding Seminar Nasional Kesehatan 1 (January 19, 2022): 2269–77. http://dx.doi.org/10.48144/prosiding.v1i.1049.

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AbstractBandotan leaves (Ageratum conyzoides L.) have antibacterial activity due to flavonoid compounds, saponins, alkaloids, terpenoids, and tannins. Itchy skin problems due to infection with Staphylococcus aureus bacteria that often occur in the community. The use of antibacterial ointments can treat skin infections caused by bacteria. The purpose of this study was to test the antibacterial effectiveness of bandotan leaf extract ointment formulations against Staphylococcus aureus bacteria. This research method is experimental research using well diffusion. The concentration of bandotan leaf extract ointment was 5%,7% and 10% with negative control, namely ointment without extract and positive control using Mupirocin ointment. The results showed that bandotan leaves (Ageratum conyzoides L.) could be formulated as ointment preparations and met the quality requirements of ointment preparations, including organoleptic test, homogeneity test, pH test, spreadability test and adhesion test. The results of this study showed that the average inhibition zone diameter of formula 1 was 4.98 mm, formula 2 was 5.20 and formula 3 had the largest inhibition zone with an average of 6.86 mm. Data obtained by the formation of a clear inhibition zone for 24 hours after treatment. The data obtained were analyzed by one way ANOVA resulting in a sig value of 0.191 > 0.05.Keywords: Antibacterial; Bandotan leaves; Evaluation; ointment; Staphylococcus aureus ATCC 25923 AbstrakDaun bandotan (Ageratum conyzoides L.) memiliki aktivitas antibakteri karena senyawa flavonoid, saponin, alkaloid, terpenoid, dan tannin. Permasalahan kulit gatal karena infeksi bakteri Staphylococcus aureus yang sering terjadi di masyarakat. Penggunaan salep antibakteri dapat mengatasi infeksi kulit yang disebabkan oleh bakteri. Tujuan dari penelitian ini untuk menguji efektivitas antibakteri formulasi sediaan salep ekstrak daun bandotan terhadap bakteri Staphylococcus aureus. Metode penelitian ini adalah penelitian eksperimental dengan menggunakan difusi sumuran. Konsentrasi salep ekstrak daun bandotan 5%,7% dan 10% dengan kontrol negatif yaitu salep tanpa ekstrak dan kontrol positif dengan menggunakan salep Mupirocin. Hasil penelitian menunjukkan bahwa daun bandotan (Ageratum conyzoides L.) dapat diformulasikan sebagai sediaan salep dan memenuhi persyaratan mutu sediaan salep, diantaranya uji organoleptik, uji homogenitas, uji pH, uji daya sebar dan uji daya lekat. Hasil penelitian diameter zona hambat rata-rata formula 1 sebesar 4,98 mm, formula 2 sebesar 5,20 dan formula 3 memiliki zona hambat yang paling besar yaitu dengan rata-rata 6,86 mm data yang diperoleh dari terbentuknya zona hambat bening selama 24 jam setelah perlakuan. Data yang diperoleh dianalisis dengan one way ANOVA dihasilkan nilai sig 0,191 > 0,05.Kata kunci: Antibakteri, Daun Bandotan, Evaluasi, Salep, Staphylococcus aureus ATCC 25923

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Tefu, Meti OFI, and Dian Ristiani Sabat. "The inventory of local wisdom: Amanuban-Dawanese medicinal plant in Timor Tengah Selatan District." Biosfer 15, no. 1 (April 7, 2022): 110–22. http://dx.doi.org/10.21009/biosferjpb.21253.

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One of the preserved local wisdom of Dawanese (Amanuban) Timor Tengah Selatan District is using plants as traditional medicine. The Dawanese (Amanuban) knowledge of using herbal plants is inherited spontaneously based on the experience and skill of the ancestors. The knowledge is inherited orally and limited to family members and siblings. This research aims to invent species of plants, the plant parts, and their functions used by Dawanese (Amanuban) as traditional medicine. This research is descriptive qualitative research with observation and structured interviews as the instruments. The informants were chosen based on Purposive Sampling using Snowball Sampling. There are 40 informants in this research. The data in this research were analysed using the descriptive qualitative analysis technique and were tabulated in tables. Based on the research result, there are 103 species of plants used by Dawanese (Amanuban) as traditional medicine. Of the 103 kinds of plants used to treat 23 groups of diseases. The way to mix the traditional medicine by Dawanese (Amanuban) varies depending on the species of plants, the parts of plant used, and the species of disease cured. The general way used by Dawanese (Amanuban) is by boiling. The novelty of this research is the disclosure of local wisdom in the use of plants owned by the Dawanese (Amanuban) people. The results of this study are expected to support the preservation of biological and cultural resources. Therefore, it is necessary to identify further the Kulit Pahit (Melicope) plants that have not been identified to the species level.

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Laksmi, Made Hermina, Ni Luh Putu Ratih Vibriyanti Karna, Herman Saputra, Aurelia Stephanie, and Putu Gde Hariwangsa. "Epidermolisis bulosa tipe distrofik resesif dengan gizi buruk tipe marasmus pada seorang anak laki-laki: sebuah laporan kasus." Intisari Sains Medis 13, no. 2 (August 30, 2022): 543–48. http://dx.doi.org/10.15562/ism.v13i2.1490.

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Background: Epidermolysis bullosa (EB) is characteristized of epithelial cell adhesion disorders that cause skin fragility and bullae after minor trauma or friction. EB Classification is based on the skin's morphological appearance and the degree to which The following reports a case of recessive dystrophic bullous epidermolysis with marasmus type malnutrition Case Report: An 8-year-old man, with complaints of wounds almost all over his body, initially in the form of bubbles filled with fluid which then burst into sores and over time, the bullae spread almost all over the body and oral mucosa. The patient has difficulty eating because of the frequent appearance of sores, so he becomes malnourished with the type of marasmus. The type of ED is inherited in an autosomal recessive manner. Since the age of 4 years, the patient's teeth began to decay, and the patient's fingers and toes were pseudosyndactyly. Histopathological examination results support severe generalized dystrophic recessive type EB (Hallopeau-Siemens). The patient treats with a compress of 0.9% NaCl for 10-15 minutes every 8 hours topically on erosional lesions, giving Petroleum jelly every 12 hours on the whole body, treating the wound using tulle, and then covering it with gauze every 24 hours, providing clinical improvement. Conclusion: Epidermolysis bullosa (EB) can be inherited in an autosomal recessive manner. Complaints of the fragility of the skin already appear at the age of children. Nutritional disorders are a problem that strengthens the condition of EB patients. Multidisciplinary management is needed to provide a good outcome. Latar Belakang: Epidermolysis bullosa (EB) memiliki karakteristik gangguan adhesi sel epitel yang menyebabkan kerapuhan pada kulit dan bula setelah terkena trauma atau gesekan ringan. Berikut dilaporkan satu kasus epidermolisis bulosa distrofik resesif dengan gizi buruk tipe marasmus Laporan Kasus: Laki- laki usia 8 tahun, dengan keluhan adanya luka hampir pada seluruh tubuh, berbentuk awal berupa gelembung berisi cairan yang kemudian pecah menjadi luka dan seiring jalannya waktu bula menyebar hampir seluruh tubuh hingga bagian mukosa mulut. Pasien mengalami kesulitan makan karena sering muncul luka sehingga menjadi gizi buruk dengan tipe marasmus. Tipe ED diturunkan secara autosomal resesif. Sejak usia 4 tahun gigi pasien mulai keropos, jari tangan dan jari kaki pasien pseudosyndactyly. Hasil pemeriksaan histopatologi menunjang gambaran epidermolisis bulosa. Pasien mengarah pada EB tipe resesif distrofik generalisata berat (Hallopeau-Siemens). Penatalaksanaan berupa kompres terbuka NaCl 0.9% selama 10-15 menit tiap 8 jam topikal pada lesi erosi, pemberian Petroleum jelly tiap 12 jam pada seluruh tubuh, rawat luka menggunakan tulle kemudian ditutup dengan kasa tiap 24 jam memberikan perbaikan klinis Simpulan: Epidermolysis bullosa dapat diturunkan secara autosomal resesif. Keluhan kerapuhan pada kulit sudah tampak pada usia anak-anak. Gangguan nutrisi menjadi permasalahan yang mempererat keadaan penderita EB. Tatalaksana multidisiplin diperlukan untuk memberikan luaran yang baik

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Fatimatunnisa, Isna, S. Slamet, St Rahmatullah, and Dwi Bagus Pambudi. "Uji Efektivitas Antibakteri Sediaan Salep Ekstrak Daun Puring (Codiaeum variegatum (L.) Rumph. Ex A.Juss) Terhadap Bakteri Staphylococus aureus." Prosiding Seminar Nasional Kesehatan 1 (December 7, 2021): 1005–15. http://dx.doi.org/10.48144/prosiding.v1i.781.

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AbstractIndonesia is one of the rich countries among the plant’s potential medicinal properties is the puring leaf (Codiaem variegatum (L.) Rumph. Ex A.Jus) as an antibacterial. The puring leaves contain flavonoid, steroids, alkaloids, tannins, saponins and fenols. which serve as antibacterial. The use of antibacterial ointments can treat bacterial skin infections. Balm is a half-denser is intended for topical wear on the skin or the mucous membranes. Among the causes of infection is the Staphylococus aureus bacteria. The study aims to test the effectiveness of a suppressive antibacterias, the leaf extract ointment against the Staphylococus aureus bacteria. Extraction methods maceration method use a 96% solution. The research method used was oriental. The extract of the puring leaves used is 2,5%, 5%, 7,5%, 10%, the negative cotrol of the ointment without the extract and the positive control with the gentamicin ointment. Zone research is inhibiting every single formula. Averag buffer zone on formula 1 6.25 mm, formula 2 7.55 mm, formula 3 9.23 mm and formula 4 11.68 mm. Data acquired by the formation of a clear buffer zone around the commonwealth for 24 hours after treatment. The data was analyzed with one way ANOVA continues the post hoc test (Tukey). The result is that partial extract of puring leave can be made into unguent and effective Staphylocous aureus ATCC 25923Keywords: Extract of puring leaves; antibacterial; ointment and staphylococus aureus AbstrakIndonesia merupakan salah satu negara yang kaya akan keaneragaman tanaman yang memiliki potensi sebagai bahan obat, salah satunya yaitu daun puring (Codiaeum variegatum (L.) Rumph. Ex A.Juss) sebagai antibakteri. Daun puring memiliki senyawa flavonoid, steroid, alkaloid, tannin, saponin dan fenol yang berfungsi sebagai antibakteri. Penggunaan salep antibakteri dapat mengobati infeksi kulit yang disebabkan oleh bakteri. Salep merupakan sediaan setengah padat yang ditujukan untuk pemakaian topikal pada kulit atau selaput lendir. Salah satu penyebab infeksi adalah bakteri Staphylococcus aureus. Penelitian ini bertujuan untuk menguji efektivitas antibakteri sediaan salep ekstrak daun puring terhadap bakteri Staphylococus aureus. Metode ekstraksi menggunakan metode maserasi dengan pelarut 96%. Metode penelitian yang digunakan yaitu sumuran. Konsentrasi ekstrak daun puring yang digunakan adalah 2,5%, 5%, 7,5%, 10%, kontrol negatif yaitu salep tanpa ekstrak dan kontrol positif dengan salep gentamicin. Hasil penelitian zona hambat setiap formula berbeda. Rata-rata zona hambat pada formula 1 6,25 mm, formula 2 7,55 mm, formula 3 9,23 mm dan formula 4 11,68 mm. Data yang diperoleh dengan terbentuknya zona hambat bening di sekeliling sumuran selama 24 jam setelah perlakuan. Data dianalisa dengan one way ANOVA dilanjutkan uji post Hoc (Tukey). Kesimpulannya Ekstrak daun puring bisa dibuat sediaan salep dan ekstrak daun puring efektif terhadap bakteri Staphylococus aureus ATCC 25923Kata Kunci: Ekstrak daun puring; antibakteri; salep dan staphylococus aureus

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Hasan, Puput Herawati, Fatimawali Fatimawali, and Widdhi Bodhi. "UJI DAYA HAMBAT EKSTRAK RIMPANG LENGKUAS PUTIH (Alpinia galanga L. Swartz) TERHADAP PERTUMBUHAN BAKTERI Klebsiella pneumoniae ISOLAT SPUTUM PADA PENDERITA PNEUMONIA RESISTEN ANTIBIOTIK SEFTRIAKSON." PHARMACON 8, no. 1 (February 28, 2019): 22. http://dx.doi.org/10.35799/pha.8.2019.29229.

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ABSTRACT White galangal rhizome (Alpinia galanga L. Swartz) is one of the plants which has the antibacterial properties from the zingiberaceae family. Empirically it can treat various diseases such as chest pain, throat inflammation, stomach inflammation, rheumatism, diabetes and skin diseases. White galangal rhizome contains flavonoids, tannins, quinones and terpenoids. This study aims to determine the antibacterial activity of white galangal rhizome extract (Alpinia galanga L. Swartz) and test its inhibition against the growth of Klebsiella pneumoniae bacteria which are resistant to ceftriaxone antibiotics. The white galangal rhizome was extracted by maceration method using 96% ethanol solvent and antibacterial activity was tested using the disc and well method with a concentration difference of 100%, 75%, 50%, 25% and 12.5%. The results showed that white galangal rhizome extract (Alpinia galanga L. Swartz) had antibacterial activity against the bacterium Klebsiella pneumoniae and could inhibit the growth of Klebsiella pneumoniae bacteria. On the disc method for concentrations of 100%, 75%, 50%, 25% and 12.5%, the inhibitors were categorized as medium. Whereas in the well method for concentrations of 100% and 75%, the inhibitors were categorized as strong, for concentrations of 50%, 25%, and 12.5%, which have a medium category.Keywords: White Galangal Rhizome (Alpinia galanga L. Swartz), Klebsiella pneumoniae ABSTRAK Rimpang Lengkuas putih (Alpinia galanga L. Swartz) merupakan salah satu tanaman yang memiliki khasiat sebagai antibakteri dari family zingiberaceae. Secara empiris dapat mengobati berbagai penyakit seperti nyeri dada, radang tenggorokkan, radang lambung, rematik, diabetes dan penyakit kulit. Rimpang Lengkuas putih mengandung senyawa flavonoid, tanin, kuinon dan terpenoid. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak rimpang Lengkuas putih (Alpinia galanga L. Swartz) dan menguji daya hambatnya terhadap pertumbuhan bakteri klebsiella pneumoniae yang resisten terhadap antibiotik seftriakson. Rimpang Lengkuas putih diekstraksi dengan metode maserasi menggunakan pelarut etanol 96% dan dilakukan pengujian aktivitas antibakteri dengan menggunakan metode cakram dan sumuran dengan perbedaan konsentrasi 100%, 75%, 50%, 25% dan 12,5%. Hasil penelitian menunjukkan bahwa ekstrak rimpang Lengkuas putih (Alpinia galanga L. Swartz) memiliki aktivitas antibakteri terhadap bakteri Klebsiella pneumoniae dan dapat menghambat pertumbuhan bakteri Klebsiella pneumoniae. Pada metode cakram untuk konsentrasi 100%, 75%, 50%, 25% dan 12,5% memiliki daya hambat yang dikategorikan sedang. Sedangkan pada metode sumuran untuk konsentrasi 100% dan 75% memiliki daya hambat yang dikategorikan kuat, untuk kosentrasi 50%, 25%, dan 12,5% memiliki daya hambat yang dikategorikan sedang.Kata Kunci: Rimpang lengkuas putih (Alpinia galanga L. Swartz), Klebsiella pneumoniae

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Ibo, Leberina Kristina, and Nissa Arifa. "Ethnomedicine Of Medicinal Plants Used By Tribal Community In Kaliki Village, Merauke - Papua." Al-Kauniyah: Jurnal Biologi 14, no. 1 (April 30, 2021): 90–100. http://dx.doi.org/10.15408/kauniyah.v14i1.15877.

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AbstrakPapua memiliki keanekaragaman hayati yang tinggi dengan jenis hutan yang lengkap dan flora endemik yang tidak ditemukan di daerah lain, serta pengetahuan tradisional tumbuhan obat masyarakat Papua sangat beragam. Namun pengetahuan tersebut belum diungkapkan dan di dokumentasikan dengan baik, seperti pengetahuan masyarakat suku Marind di Kampung Kaliki Merauke yang merupakan salah satu suku terbesar yang menempati pesisir pantai hingga perbatasan Papua New Guinea. Penelitian etnomedisin tumbuhan obat dimaksudkan untuk mengungkapkan presepsi dan konsepsi masyarakat lokal dalam memahami kesehatan seperti pengunaan tumbuhan sebagai bahan obat, sekaligus untuk melakukan inventarisasi keanekaragaman jenis tumbuhan berguna untuk obat-obatan tradisional dan sebagai data awal untuk riset farmasi dalam menemukan senyawa baru yang berguna dalam pengobatan. Metode penelitian dilakukan melalui pendekatan emik dan etik juga melakukan wawancara secara terbuka dan pengamatan langsung di lapangan. Hasil penelitian menunjukan sebanyak 34 spesies dari 22 famili dikenali dan dimanfaatkan untuk menyembuhkan berbagai penyakit. Daun merupakan bagian tumbuhan yang paling banyak dimanfaatkan sebagai bahan obat yaitu sebanyak 18 spesies, kulit batang 8 spesies dan akar rimpang 3 spesies. Sebagian besar pengolahan tumbuhan obat melalui metode perebusan dan konsumsi langsung. Tumbuhan obat ini dimanfaatkan untuk pengobatan 15 jenis penyakit. Persalinan dan diare merupakan pengobatan yang paling banyak memanfaatkan tumbuhan obat. AbstractPapua is rich in biodiversity with several forest types and endemic flora that cannot be found anywhere else in the world. Furthermore, diverse traditional knowledge of medicinal plants are already used by tribal community in Papua. However, this knowledge has not been published and well documented. For example, the knowledge of the Marind Tribe in Kaliki Village, Merauke, which is one of the largest tribes living on the coast to the border of Papua New Guinea. Research of ethnomedicine on medicinal plants is intended to reveal the perception and conception of local communities in understanding health, such as the utilization of plants as medicine, inventory of plant used in traditional medicines, and preliminary data for pharmaceutical research to find new compounds for drug discovery. This study used emic and ethical approaches, open-ended interviews, and direct field observations. According to study result, a total of 34 species from 22 families were identified and used to cure various diseases. It was found that plant parts most widely used as medicinal ingredients were leaves of 18 species, bark of 8 species, and rhizome of 3 species. Moreover, medicinal plants were normally boiled or processed for direct consumption. The medicinal plant was used to treat 15 species of diseases. In addition, medicinal plants were mostly used in childbirth care and treating diarrhea.

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Yuliani, Nia, Amry Syawaalz, and Mawaddah Lisna. "EKSTRAKSI DAN IDENTIFIKASI PENDAHULUAN GOLONGAN SENYAWA FENOL DARI RIMPANG LENGKUAS MERAH (Alpinia purpurata (Vieill) K. Sch)." Jurnal Sains Natural 1, no. 2 (November 25, 2017): 111. http://dx.doi.org/10.31938/jsn.v1i2.19.

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Extraction and Identification of Phenol Compounds Group Introction galanga Rhizome RED (Alpinia purpurata (Vieill) K. Sch) Indonesia is a country rich in natural resources with a variety of crops are grown, one of which is a spice plant. Plant herb is a plant that is used in addition to the food manufacturing process is also used as potential drugs medicines, such that the red ginger (Alpinia purpurata (Vieill) K. Sch). Red ginger is a plant that has been known to have the potential to cure many diseases. Generally, people use the red ginger to treat diarrhea and skin diseases caused by fungi. Ginjer contains phenol red that could serve as an antibacterial. The study was conducted to extract the phenolic compounds and identify them by Gas Chromatography and Mass Spectrometry (GCMS), with the following steps: extraction of samples, testing of phenolic compounds, and identification of phenolic compounds by GCMS. According to the research and identification was carried out on the red rhizome ethanol extract, we could conclude that the phytochemical tests showed positive rhizome containing phenol red. And from the GCMS got some phenolic compounds contained in the ethanol extract of rhizome of red, one compound with a molecular weight of 164 g / mol with molecular formula C10H12O2 .Keyword : Red gingge (Alpinia purpurata (Vieill) K. Sch), compound fenol, extraction, GCMS. ABSTRAK Indonesia merupakan negara yang kaya dengan sumber daya alam dengan berbagai jenis tanaman yang tumbuh, salah satu diantaranya adalah tanaman rempah - rempah. Tanaman rempah merupakan tanaman yang dimanfaatkan selain untuk proses pembuatan makanan juga cukup potensial dimanfaatkan sebagai obat – obatan, diantaranya yaitu lengkuas merah (Alpinia purpurata (Vieill) K. Sch). Lengkuas merah merupakan tanaman yang telah diketahui berpotensi dapat mengobati berbagai macam penyakit. Umumnya masyarakat menggunakan lengkuas merah untuk mengobati diare dan penyakit kulit yang disebabkan oleh jamur. Lengkuas merah mengandung senyawa fenol yang dapat berfungsi sebagai antibakteri. Penelitian ini dilakukan untuk mengekstraksi senyawa fenol dan mengidentifikasinya dengan Gas Chromatography dan Mass Spectrometry (GCMS), dengan melalui beberapa tahapan yaitu ekstraksi sampel, uji senyawa fenolik, dan identifikasi senyawa fenolik dengan GCMS. Berdasarkan hasil penelitian dan identifikasi yang telah dilakukan pada ekstrak etanol rimpang lengkuas merah, dapat disimpulkan bahwa uji fitokimia menunjukkan rimpang lengkuas merah positif mengandung senyawa fenol. Dan dari hasil GCMS didapatkan beberapa senyawa fenol yang terkandung pada ekstrak etanol rimpang lengkuas merah, salah satunya senyawa dengan berat molekul 164 g/mol yang mempunyai rumus molekul C10H12O2.Kata kunci : Lengkuas merah (Alpinia purpurata (Vieill) K. Sch), senyawa fenol, ekstraksi, GCMS.

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Naftali, Disha, and Farid Rusdi. "Hubungan Motif Penggunaan Informasi dalam Beauty Journal dengan Kepuasan Pengunjung Website Sociolla.com (Survei Terhadap Perempuan Pengguna Situs Sociolla.com)." Prologia 5, no. 1 (March 4, 2021): 74. http://dx.doi.org/10.24912/pr.v5i1.8132.

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Many ways are used to support the appearance properly one of which is to treat the body and use beauty products. Many quality products offered by Sociolla.com sometimes make users also confused to choose the best product for their conditions. With the Beauty Journal feature, users can find out in advance superior products that are in accordance with the user's skin condition, based on price, based on local brands and others. The purpose of this study was to determine the effect of the relationship between the motives for using information in the Beauty Journal with the satisfaction of Sociolla.com website visitors. This study uses a quantitative approach. The theoretical foundation used in this research is uses and gratification and online media. The independent variable in this study is the motive for using Beauty Journal information and the dependent variable is the level of satisfaction of website visitors at sociolla.com on the information in the Beauty Journal feature. Researchers used a purposive sampling technique with 100 respondent sample. Data collection was carried out by distributing questionnaires in the form of Google Forms consisting of 30 indicators. Data analysis techniques used correlation coefficients, simple linear regression analysis and coefficient of determination. The final result obtained is the motive for using information in the Beauty Journal to influence the satisfaction of visitors to the website sociolla.com.Banyak cara yang digunakan untuk menunjang penampilan dengan baik salah satunya adalah dengan merawat tubuh dan menggunakan produk kecantikan. Banyak produk yang berkualitas yang ditawarkan oleh Sociolla.com terkadang membuat pengguna juga bingung untuk memilih produk yang terbaik untuk kondisi mereka. Dengan adanya fitur Beauty Journal, pengguna bisa mencari tahu terlebih dahulu produk unggulan yang sesuai dengan kondisi kulit pengguna, berdasarkan harga, berdasarkan merek lokal dan lain-lain. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh hubungan motif penggunaan informasi dalam Beauty Journal dengan kepuasan pengunjung website Sociolla.com. Penelitian ini menggunakan pendekatan kuantitatif. Landasan teori yang digunakan dalam penelitian ini yaitu uses and gratification dan media online. Variabel independen pada penelitian ini adalah motif penggunaan informasi Beauty Journal dan variabel dependen adalah tingkat kepuasan pengunjung website sociolla.com terhadap informasi dalam fitur Beauty Journal. Peneliti menggunakan teknik purposive sampling dengan sampel sebanyak 100 responden. Pengumpulan data dilakukan dengan menyebarkan kuisioner berupa Google Forms yang terdiri dari 30 indikator. Teknik analisis data menggunakan koefisien korelasi, analisis regresi linear sederhana dan koefisien determinasi. Hasil akhir yang diperoleh adalah motif penggunaan informasi dalam Beauty Journal berpengaruh terhadap kepuasan pengunjung website sociolla.com.

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Apriliani, Nurul Fitria, and Gading Wilda Aniriani. "ANALISIS UJI MIKROBIOLOGI DAN LOGAM BERAT PADA SCRUB BERBAHAN DASAR KAPUR SIRIH." JURNAL ILMIAH SAINS 17, no. 2 (October 11, 2017): 126. http://dx.doi.org/10.35799/jis.17.2.2017.17279.

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ANALISIS UJI MIKROBIOLOGI DAN LOGAM BERAT PADA SCRUB BERBAHAN DASAR KAPUR SIRIHABSTRAKKapur sirih dibuat dari pengolahan batu kapur hasil pembakaran yang direndam dalam air dalam waktu satu sampai dua minggu sampai hancur dan berbentuk seperti pasta. Kapur sirih ini pada zaman dahulu digunakan oleh para orang tua sebgai campuran ramuan untuk merawat gigi.sedangkan pada pengobatan-pengobatan tradisional juga digunakan sebagai obat mengatasi gusi bengkak,bisul,masalah haid serta penyakit kulit seperti menghilangkan jerawat, menghilangkan bau badan serta memutihkan ketiak. Atas dasar itulah penelitian ini menggunakan bahan dasar kapur sirih agar bisa digunakan sebagai alternatif pemanfaatan kapur sirih. Pembuatan scrub di buat dengan bahan dasar kapur sirih dicampur dengan bahan lain seperti beras, minyak zaitun, minyak lavender,metil paraben,dan air jeruk nipis. Scrub dibuat dengan variasi penambahan kapur sirih. Dari formulasi yang dibuat kemudian diamati yang paling bagus berdasarkan pengamatan organoleptik dan dilakukan beberapa uji. Uji mikrobiologi sampel menunjukkan bahwa hasil dari Uji Angka Lempeng Total sebesar 5,0 x 105 Cfu/g dan Angka Kapang Khamir sebesar 1,6 x 104 Cfu/g tidak memenuhi persyaratan yang ditetapkan oleh BPOM. Sedangkan cemaran bakteri Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans serta cemaran logam berat Pb dan Hg adalah negatif.Kata Kunci : Kapur sirih, Scrub dan Mikrobiologi ANALYSIS OF MICROBIOLOGY AND HEAVY METALS TEST IN SCRUB FROM LIME BETELABSTRACTLime betel made from the processing of limestone combustion results are immersed in water within one to two weeks until destroyed and shaped like a paste. This Lime betel is used in the past by the parents sebgai mix of ingredients to treat teeth. While on traditional treatments are also used as a remedy to overcome swollen gums, boils, menstrual problems and skin diseases such as eliminating acne, eliminate body odor and whiten armpits. On that basis this research using the basic ingredients of Lime betel to be used as an alternative utilization of Lime betel . Preparation of scrubs made with basic ingredients of lime betel mixed with other ingredients such as rice, olive oil, lavender oil, methyl paraben, and lime juice. Scrub made with variations of addition of Lime betel . From the formulation made then the best observed based on organoleptic observation and conducted several tests. The sample microbiological test showed that the results from the Total Plate Numbers Test of 5.0 x 105 Cfu / g and the Kapang Khamir Figures of 1.6 x 104 Cfu / g did not meet the requirements set by BPOM. While bacterial contamination Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans and heavy metal contamination Pb and Hg is negative. Key Words: Lime betel, Scrub,Microbiology

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Mustafa, Nikita Tenritojang, Dini Kurnia Ikliptikawati, and Abdul Wahid Jamaluddin. "Perbandingan Pemberian Madu Lokal Bunga Cengkeh (Syzygium aromaticum) dan Madu Impor Bunga Manuka (Leptospermum scoparium) Secara Topikal Terhadap Penyembuhan Luka Sayat Pada Mencit Putih (Mus musculus)." Jurnal Pharmascience 6, no. 2 (November 20, 2019): 25. http://dx.doi.org/10.20527/jps.v6i2.7347.

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ABSTRAK Luka merupakan trauma fisik mengakibatkan kulit terbuka. Luka merupakan jalur masuk bagi mikroorganisme dari luar penyebab infeksi. Dahulu madu dimanfaatkan untuk mengobati luka bakar dan luka sayat. Madu memiliki keunggulan yakni memiliki hidrogen peroksida, eugenol dan methylglyoxal yang merupakan antibiotik yang unggul. Penelitian ini dilakukan dengan uji ekperimental. Hewan coba dibagi dalam 4 kelompok. Setiap kelompok diberikan perlakukan antara lain: dengan pemberian madu lokal, madu impor, dan salep povidone iodine (kontrol positif), dan kelompok kontrol negatif tanpa perlakuan. Dilanjutkan pemantauan dan pencatatan untuk proses penyembuhan tiap kelompok. Hal ini diukur dengan indikator antara lain: luas luka, kelembaban luka, warna, serta perubahan keropeng. Pada penelitian ini ditemukan bahwa dengan pemberian madu mempercepat proses penyembuhan luka dibandingkan dengan pemberian air dan povidone iodine (p<0,05). Selain itu ditemukan madu lokal memberikan efek penyembuhan luka yang lebih cepat dibandingkan madu impor. Pemberian madu memberikan efek yang lebih baik terhadap penyembuhan luka. Dibandingkan dengan pemberian salep Povidone iodine dan tanpa perlakuan.Kata kunci : Madu Bunga Cengkeh, Madu Bunga Manuka, Waktu penyebuhan, Warna Luka, Kelembaban. ABSTRACT Wound is a physical trauma causes discontinuity, Leads physiological dysfunction. Wound is an entry point for microorganisms from outside as source of infection. In the past, honey was used to treat burns and cuts. Honey is a natural ingredient as a moist wound-dressings. Besides that, honey contain hydrogen peroxide, eugenol, and methylglyoxal which is a superior antibiotic. This research was carried out by experimental test. The experimental animals were divided into 4 groups, each group consisted of 6 animals. Each group is treated, among others; by giving local honey, imported honey, povidone iodine (positive control), and negative control group without a treatment. Continued monitoring and recording for the healing process of each group. Statistical analysis is performed by calculation of frequency distribution and Independent-t, Anova, and regression analysis to determine the relationship between each variable. Statistical test results are significant if the value of p <0.05. This research found that addition of honeyaccelerated the wound healing process compared to the administration of water and povidone iodine (p <0.05). This is measured by indicators including; wide wounds, moisture wounds, colour change, and scab changes. By giving honey the perfect wound healing process begins on the 11th day until the 13th day. Besides that, local honey is found to provide healing effects that are faster than imported honey. Giving honey provides a better effect on wound healing. compared with Povidone iodine and without a treatment Keywords: Clove Flower Honey, Manuka Flower Honey, Time of Wasting, Colour of Wound, Moisture

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WIDODO, WAHYU, and ARYO NUGROHO TRIYUDANTO. "Uncommon Glomus Tumor at The Volar Area of Distal Phalang: a Case Report." Indonesian Journal of Cancer 11, no. 1 (January 15, 2017): 29. http://dx.doi.org/10.33371/ijoc.v11i1.498.

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ABSTRACTIntroduction: Glomus tumor, a benign rare neoplasmic perivascular lesion arising from glomus neuromial-arterial tissue. Glomus cells, which are found in the dermis throughout the body, are responsible for thermoregulation. In this tumor, its cells proliferate and surround the vascular canals, producing a classic clinical sign such as spontaneous pain, pain on light touching, and temperature hyperesthesia. Despite its rare occurrence, it is necessary to know how recognize and treat this variant of perionychium tumor. Case Illustration: A forty-seven-year old woman came with pain on the tip of her ring finger since 3 years before admission. Over time, the tingling sensation worsened and eventually pain emerged. The appearance of her ring finger and nail were normal. However, the patient felt pain after a light touch and paresthesia especially at the volar side of her ring finger. Having normal radiograph appearance, excisional biopsy was then performed. Histologic examination showed a well-defined lesion encapsulated by a fibrous capsule. The lesion consisted of several thin-walled flared vascular containments with layers of glomus cells around it, which is in accordance with characteristic of benign glomus tumor.At the latest follow up, there were no complication or recurrence found. The pain and paresthesia around the ring finger were also diminished. Conclusion: Despite its rare occurrence, the diagnosis of Glomus Tumor can be performed clinically. Excisional biopsy is the definitive treatment and specific diagnostic modality for Glomus Tumor.ABSTRAKGlomus tumor adalah tumor jaringan lunak yang cukup jarang ditemui dan merupakan lesi perivaskular yang muncul dari arteri glomus neuromial. Sel glomus berproliferasi dan mengelilingi kanal vaskular. Tumor ini sering ditemukan pada area subungual. Tanda khasnya adalah nyeri spontan, nyeri pada sentuhan ringan, dan sensitivitas terhadap suhu. Kemampuan mengenali dan mengobati tumor perionychium ini penting. Wanita usia 47 tahun datang dengan keluhan utama nyeri pada jari manis sejak 3 tahun lalu. Seiring waktu, sensasi kesemutan dan nyeri memburuk. Pada pemeriksaan fisik di regio distal phalang tidak ditemukan bengkak dan kemerahan, deformitas, atau massa. Kulit intak tanpa perubahan warna dengan sekitar. Kuku tampak normal. Pada palpasi didapatkan nyeri pada sentuhan ringan di area volar dengan VAS 4-5 dan paresthesia pada sisi volar. Pemeriksaan x-ray menunjukkan hasil normal. Pada pemeriksaan biopsi eksisional dan pemeriksaan histopatologi ditemukan lesi berbatas tegas yang terdiri atas kapsula fibrosa dengan beberapa lapis dinding dan vaskular serta sel glomus yang menutupinya. Tiga bulan pasca-operasi tidak ditemukan nyeri dan paresthesia pada lokasi tumor. Tumor glomus adalah tumor yang jarang dan dapat didiagnosis melalui tampilan klinis. Biopsi eksisional merupakan pengobatan definit, sekaligus modalitas diagnostik spesifik.

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Suharto, Gusti muhammad Fuad, and Rory Denny Saputra. "Efektivitas Blok Transversus Abdominis Plane Pasca Operasi Caesar." Jurnal Anestesi Obstetri Indonesia 3, no. 1 (May 12, 2020): 59–71. http://dx.doi.org/10.47507/obstetri.v3i1.23.

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Operasi caesar merupakan prosedur bedah yang paling umum dilakukan di seluruh dunia. Operasi ini menyebabkan nyeri pasca operatif sedang hingga berat sebagai akibat insisi pfannenstiel yang umumnya dikaitkan dengan rasa nyeri pada uterus dan somatik pada dinding abdomen. Analgesia pasca operasi yang memadai pada pasien obstetrik sangat penting karena mereka memiliki kebutuhan pemulihan bedah yang berbeda, yaitu meliputi menyusui dan perawatan bayi baru lahir, hal ini dapat terganggu jika analgesia yang diberikan tidak memuaskan. Rejimen analgesik pasca operasi yang ideal harus efektif tanpa mempengaruhi ibu untuk merawat neonates dan dengan efek transfer obat yang seminimal mungkin melalui ASI. Saat ini banyak cara yang paling aman dan efektif dari intervensi manajemen nyeri pasca operasi seperti anestesi lokal dengan infiltrasi kulit, analgesia epidural, dan blok bidang seperti blok transversus abdominis plane (TAP) dan blok ilioinguinal-iliohipogastrik (II-IH). Blok TAP merupakan teknik anestesi regional dimana serabut saraf aferen yang menginervasi dinding abdomen bagian anterolateral diblokir dengan mengguakan anestesi lokal di bidang transversus abdominalis. Potensinya dalam meningkatkan kualitas dan durasi analgesia setelah berbagai operasi abdomen bawah sudah tidak bisa dipungkiri lagi. Sekarang, dengan bantuan USG menjadikan blok TAP sebagai metode yang aman dan efektif untuk memberikan analgesia pasca operasi caesar dibandingkan dengan perawatan standar pasca operasi. Selain itu, blok TAP juga dikaitkan dengan pengurangan konsumsi opioid, peningkatan kepuasan pasien, dan efektif untuk mengurangi nyeri dibandingkan dengan teknik analgesia lainnya. Efficacy of Transversus Abdominis Plane Block After Post Caesarean Section Delivery Abstract Caesarean section is the most common surgical procedure performed worldwide. This operation causes moderate to severe postoperative pain as a result of pfannenstiel incision which is commonly associated with pain in the uterus and somatic in the abdominal wall. Adequate postoperative analgesia in obstetric patients is very important because they have different surgical recovery needs, which include breastfeeding and newborn care, this is can be disrupted if the analgesia given is not satisfactory. The ideal postoperative analgesic rejimen must be effective without affecting the mother to treat the neonate and with minimal effect of drug transfer through breast milk. There are currently many of the safest and effective ways of interventions for postoperative pain management such as local anesthetic skin infiltration, epidural analgesia, and field block like TAP and II-IH. TAP block is a regional anesthetic technique where afferent nerve fibers that innervate the anterolateral abdominal wall are blocked by using local anesthesia in the transverse abdominal plane area. Potential in improving the quality and duration of analgesia after various lower abdominal operations is inevitable. Now, with ultrasound guiding, the TAP block is a safe and effective method for providing analgesia post caesarean section delivery compared to standard postoperative care. In addition, TAP block is also associated with a reduction of opioid consumption, increased patient satisfaction, and is effective in reducing pain compared to other analgesia technique.

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Lestari, Novi, and Diah Indriani. "Pola Kepemilikan Sumber Air Minum Rumah Tangga di Jawa Timur." Media Gizi Kesmas 11, no. 1 (June 2, 2022): 88–94. http://dx.doi.org/10.20473/mgk.v11i1.2022.88-94.

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ABSTRAKLatar Belakang: Konsumsi air yang layak merupakan salah satu faktor untuk mencegah terjadinya masalah kesehatan seperti diare, kolera, disentri, tipes, cacingan, penyakit kulit, dan keracunan.. Diare menjadi penyebab kedua kematian tertinggi pada balita di seluruh dunia. masih ada beberapa daerah di Indonesia yang mengalami kekurangan air bersih dan air yang tercemar berat.Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan kepemilikan sumber air minum dan pengolahan air minum sebelum diminum dengan jenis wilayah tempat tinggal di Provinsi Jawa Timur berdasarkan data SDKI tahun 2017.Metode: Penelitian ini menggunakan data dari Survei Demografi dan Kesehatan Indonesia tahun 2017 di wilayah Jawa Timur dengan desain cross sectional. Jumlah sampel yang digunakan adalah 4113 rumah tangga. Data yang diperoleh berasal dari situs resmi DHS. Analisis yang digunakan pada penelitian ini adalah analisis Chi Square.Hasil: Hasil penelitian didapatkan adanya hubungan yang signifikan sumber air minum dan pengolahan air minum sebelum diminum dengan jenis wilayah tempat tinggal (p < 0,05). Sumber air minum dan pengolahan air minum memiliki korelasi dengan jenis wilayah tempat tinggal. Prevalensi rasio sumber air minum adalah 0,355 dan pengolahan air minum adalah 3,321.Kesimpulan: Rumah tangga di perkotaan mayoritas memiliki sumber air minum yang layak serta rumah tangga di perkotaan cenderung mengonsumsi air kemasan untuk minum. Rumah tangga di pedesaan melakukan pengolahan air minum sebelum dikonsumsi. ABSTRACTBackground: Adequate water consumption is one of the factors to prevent health problems such as diarrhea, cholera, dysentery, typhoid, intestinal worms, skin diseases, and poisoning. Diarrhea is the second highest cause of death in children under five in the world. There are still some areas in Indonesia that experience a shortage of clean water and heavily polluted water.Objectives: This study aims to determine the relationship between ownership of drinking water sources and treatment of drinking water before drinking with the type of area of residence in East Java Province based on the 2017 IDHS data.Methods: This study uses data from the 2017 Indonesian Demographic and Health Survey in the Java region. East withdesign cross sectional. The number of samples used is 4113 households. The data obtained comes from the official website of DHS. The analysis used in this study is Chi Square analysis.Results: The results of the study found a significant relationship between drinking water sources and drinking water treatment before drinking with the type of area of residence (p < 0,05). Drinking water sources and drinking water treatment have a correlation with the type of area of residence. The prevalence ratio of drinking water sources is 0,355 and drinking water treatment is 3,321.Conclusions:. The majority of households in urban areas have a decent source of drinking water and households in urban areas tend to consume bottled water for drinking. Households in rural areas treat drinking water before consumption.

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Andarini, Zahrah Prawita, Soedarmanto Indarjulianto, Alfarisa Nururrozi, Yanuartono Yanuartono, and Slamet Raharjo. "Studi Kasus: Diagnosis dan Pengobatan Stomatitis pada Kucing Domestik." Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Science) 11, no. 3 (January 1, 2022): 217. http://dx.doi.org/10.46549/jipvet.v11i3.157.

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Abstract Stomatitis is an inflammation that occurs in the oral mucosal tissue, characterized by ulcers. This case study aims to diagnose and treat stomatitis in a cat. A 7-month-old female domestic cat weighing 2.7 kg with lethargy, lost of appetite, decreased thirst, and was having sores for 2 days was examined. The cat was examined physically include anamnesis, an inspection of body condition and eating behavior, palpation of the skin, hair, and parts of the body that can be palpated, and auscultation of the thorax and abdomen. The blood sample that was examined includes the erythrocyte count, hemoglobin value, leukocytes count, and their differentials. Physical examination results showed hyperemic gingival, swollen submandibular and retropharyngeal lymphoglandula, and there were multiple ulcers on the lips and tongue. Hematological examination showed thrombocytopenia and monocytosis. The stomatitis was diagnosed to the cat with a good prognosis. Therapy was given for 5 consecutive days in the form of intramuscular injection of Amoxycillin 10 mg/kg BW twice daily, intramuscular injection of diphenhydramine HCl 1 mg/kg BW once daily, subcutaneous injection of 0.5 ml vitamin C once daily, oral administration of 0.5 ml multivitamin twice daily, and povidone-iodine for gargle twice a day applied lightly to the lesion area. Stomatitis in this case study was cured within 5 days by treating with amoxicillin, diphenhydramine HCl, vitamin C, multivitamins, and topical povidone-iodine. Keywords: Amoxicillin; Cat; Stomatitis; Vitamin C. Abstrak Stomatitis merupakan radang yang terjadi pada jaringan mukosa mulut yang ditandai adanya ulser. Studi kasus ini bertujuan melakukan diagnosis dan pengobatan stomatitis pada kucing. Studi kasus ini melaporkan seekor kucing domestik betina umur 7 bulan dengan berat badan 2,7 kg dengan keluhan lesu, tidak ada nafsu makan dan minum, serta menderita sariawan sejak 2 hari sebelum diperiksa. Kucing diperiksa secara fisik meliputi anamnesa, inspeksi terhadap kondisi tubuh dan perilaku makan, palpasi terhadap kulit, rambut, dan permukaan tubuh lainnya, serta auskultasi pada daerah thorax dan abdomen. Sampel darah kucing diperiksa terhadap jumlah eritrosit kadar hemoglobin, jumlah leukosit dan diferensialnya. Hasil pemeriksaan fisik menunjukkan limfoglandula submandibula dan retropharingeal bengkak, gingiva hiperemi serta adanya ulser multiple pada bibir dan lidah. Hasil pemeriksaan darah menunjukkan trombositopenia dan monositosis. Berdasarkan hasil pemeriksaan kucing didiagnosis stomatitis dengan prognosis fausta. Kucing diberi terapi selama 5 hari berupa amoxicilin dosis 10 mg/kg BB dua kali sehari secara intramuskuler, dyphenhidramin HCl 1 mg/kg BB satu kali sehari secara intramuskuler, vitamin C sebanyak 0,5 ml satu kali sehari secara subkutan, multivitamin sebanyak 0,5 ml dua kali sehari secara per oral, dan povidone iodine dua kali sehari dioleskan pada lesi stomatitis. Stomatitis pada kasus ini dapat disembuhkan dalam waktu 5 hari dengan pemberian amoxicilin, dipenhidramin HCl, vitamin C, multivitamin secara sistemik dan povidone iodine secara topikal. Kata kunci: Amoksisilin; Kucing; Stomatitis; Vitamin c

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Baiswar, P., P. Chandra, K. P. Mohapatra, T. L. Kipgen, S. Chandra, and S. V. Ngachan. "First Record of Rhizoctonia solani AG 1-IB on Mucuna pruriens in India." Plant Disease 97, no. 2 (February 2013): 284. http://dx.doi.org/10.1094/pdis-03-12-0316-pdn.

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Mucuna is the source of L-Dopa (L 3,4 dihydroxyphenylalanine), a precursor of a dopamine used to treat Parkinson's disease. Leaf blight symptoms were observed on Mucuna pruriens plants in October to November 2010 in a field at the Indian Council of Agricultural Research Complex for the Northeastern Hill Region, Umiam, Meghalaya, India. Symptoms included black necrotic areas on leaves, collapsed leaf tissue and, occasionally, fungal growth visible on the leaf. In advanced infections, dead leaves were attached to the stem, followed by defoliation with only infected pods still attached. Approximately 10% of plants were infected in ~0.5 ha surveyed. Symptomatic leaf pieces were washed with sterile water, surface-sterilized using 4% NaOCl for 30 s, washed again, blotted dry, and plated on PDA amended with streptomycin (100 ppm). Characteristics of three fungal isolates were typical of Rhizoctonia solani J.G. Kühn [teleomorph = Thanatephorus cucumeris (A. B. Frank) Donk], i.e., hyphal branching at 90° angles, basal constriction at the hyphal branching point with a septum close to the lateral hyphum (3), and presence of multinucleate hyphal cells confirmed using DAPI (2-(4-amidinophenyl)-1H-indole-6-carboxamidine) staining (1). A culture was deposited at the Agharkar Research Institute, Pune, India (NFCCI No. 2602). The ITS1-5.8S-ITS2 region of nuclear rDNA of one isolate was sequenced after amplification with primers ITS1 and ITS4 (4), (GenBank Accession No. JQ675536). A BLAST search revealed 99% similarity of the sequence with that of 2 R. solani AG 1-IB isolates (AB122137 and AB000039). Sequences were aligned using MAFT Version 6. Maximum parsimony analysis using MEGA 5 placed the test isolate in AG 1-IB with 99% bootstrap support. PCR assays with primers for R. solani AG 1-IB produced a DNA band of ~300 bp (2). Koch's postulates were completed by inoculating 5-mm colonized plugs of PDA at the soil line of each of 5 potted, 40-day-old plants of M. pruriens, and covering the base of each plant with moistened cheesecloth. In addition, 3 plants were inoculated with colonized plugs at the junction of the lamina and petiole of 9 leaves/plant, spraying the plants with sterilized water, and covering the plants with polythene for 3 days. In addition, 10 detached leaves were inoculated with colonized PDA plugs and incubated in a moist chamber. Three non-inoculated plants served as a control treatment for the first 2 methods, and 10 leaves as a control treatment for the third method with sterilized PDA plugs. Symptoms of leaf blight (necrosis from base to leaf tip, with abundant fungal growth) developed in 6 to 7 days on plants inoculated at the soil line, 4 days on leaves inoculated at the junction of the lamina and petiole, and 2 to 3 days on detached leaves. Control plants and leaves remained asymptomatic for all 3 methods. R. solani was reisolated from inoculated plants as described above, and confirmed to be AG 1-IB. The fungus was not reisolated from control plants or leaves. To our knowledge, this is the first record of R. solani AG 1-IB causing leaf blight on M. pruriens in India. References: (1) M. M. Kulik and P. D. Dery. Biotech. Histochem. 70:95, 1995. (2) M. Matsumoto. Mycoscience 43:185, 2002. (3) B. Sneh et al. Identification of Rhizoctonia Species. The American Phytopathological Society Press, St Paul, MN, 1991. (4) T. J. White et al. Page 315 in: PCR Protocols: A Guide to Methods and Applications. M. A. Innis et al., eds. Academic Press, San Diego, CA, 1990.

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47

Priyanto, Agus. "Hubungan tingkat pengetahuan dengan perilaku pencegahan kekambuhan luka diabetik." Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) 5, no. 3 (December 28, 2018): 233–40. http://dx.doi.org/10.26699/jnk.v5i3.art.p233-240.

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ABSTRACTLuka pada pasien diabetes mellitus yang sudah membusuk dan bisa melebar, ditandai dengan jaringan yang mati berwarna kehitaman dan berbau busuk, dan bila tidak tertangani dapat menyebabkan kematian jaringan dan bisa mengakibatkan kematian.Dalam keadan lanjut, amputasi menjadi terapi akhir untuk mencegah pelebaran luka. Penanganan luka pasca operasi dan pengetahuan tentang pencegahan terjadinya luka menjadi hal penting untuk mencegah kekambuhan ulang. Tanpa pengetahuan yang baik tentang perawatan , luka diabetik akan muncul berulang dan mengakibatkan hilangnya bagian tubuh karena kematian jaringan. Tujuan penelitian ini adalah menganalisis hubungan tingkat pengetahuan dengan perilaku pencegahan kekambuhan luka diabetik di Di Ruang Penyakit Dalam RSUD Gambiran Kediri.Desain yang digunakan dalam penelitian ini adalah korelasional. Populasinya pasien Diabed di ruang penyakit Dalam RSUD Gambiran . Sampel diambil dengan teknik consecutive samping sejumlah 29 responden.Variabel independennya adalah tingkat pengetahuan pasien tentang pencegahan luka diabetik dan variable dependennya adalah perilaku pencegahan kekambuhan luka diabetik. Data diambil dengan questioner dan dianalisis dengan Uji Spearman Rank.Hasil penelitian menunjukkan bahwa pengetahuan pasien tentang pencegahan luka diabetik adalah baik sebanyak 24 responden (82,75 %). Perilaku pencegahan luka diabetik sebagian besar adalah cukup 15 orng (51,726 %). Uji Spearman Rank menunjukkan Ada hubungan tingkat pengetahuan dengan perilaku pencegahan luka diabetik di Di Ruang RSUD Gambiran Kota Kediri (spearman rank dengan p = 0,003 < 0,05, artinya H0 ditolak dan H1diterima). Coefficient correlation = 0,404, menunjukkan adanya hubungan ke arah positif artinya semakin baik tingkat pengetahuan maka perilaku pencegahan luka diabetik juga semakin baik. Sebagai tindak lanjut dalam meningkatkan perilaku pencegahan kekambuhan luka dibetik pada pasien yang pernah menderita luka diabetik maupun yang belum pernah, perlu upaya untuk meningkatkan pengetahuan pasien dan kelarga tentang cara perawatan pasien Diabet terutama dalam menjaga kestabilan gula darah dalam batas normal,melalui pola diet dan cara pemeliharaan integritas kulit agar tidak terjadi luka dibetik. Kata Kunci : Pengetahuan, Perilaku, luka Diabetik, kekambuhanABSTRACTWound on diabetic patient signed by blacknumb tissue and badsmell, ifits not hand ledthet issue will numband tousebedie. In advanced circumstances, amputation becomes a final therapy to prevent widening of the wound.Treatment postoperative wounds and knowledge of prevention of injury are important to prevent recurrence. Without good knowledge about treatment, diabetic wounds will recur and cause loss of body parts due to necrotic tissue . The purpose of this study was to analyze the relationship between the level of knowledge with behavioral prevention of diabetic wound recurrence in the Internist Room, Gambiran Kediri Hospital. The design used in this study is correlational. The population is internist patients of Gambiran Hospital. Samples were taken by consecutive techniques totaling 29 respondents. The independent variable is the level of patient knowledge about the prevention of diabetic wounds and the dependent variable is the behavior of diabetic wound recurrence prevention. The data was taken with a questionnaire and analyzed by the Spearman Rank Test. The results showed that the patient's knowledge of the prevention of diabetic wounds was good as many as 24 respondents (82.75%). Preventive behavior of diabetic wounds is mostly 15 people (51.72%). The Spearman Rank test shows that there is a relationship between the level of knowledge with the behavioral prevention of diabetic wounds in the internist room of Gambiran Hospital (spearman rank with p = 0.003 <0.05, meaning that H0 is rejected and H1 is accepted). Coefficient correlation = 0.404, indicating a positive relationship means that the better the level of knowledge, the better the prevention behavior of diabetic wounds. As a follow-up in improving the prevention behavior of randomized wound recurrence in patients who have suffered from diabetic wounds or who have never before, it is necessary to increase the knowledge of patients and family members on how to treat diabetic patients, especially in maintaining blood sugar stability within normal limits, through diet and methods. maintenance of the integrity of the skin so that no wounds occur.Keywords: Knowledge, Behavior, Diabetic wounds, recurrence

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48

Noval, Noval, Siti Malahayati, Mia Audina, Dindawati Khadijah, Farah Noor Ain, Muhammad Rizani Faisal, Farah Santika, et al. "Pembuatan Sabun Cair dari Beras untuk Meningkatkan Perekonomian Masyarakat yang Terdampak Pandemi Covid-19." Indonesia Berdaya 3, no. 1 (January 20, 2022): 47–52. http://dx.doi.org/10.47679/ib.2022158.

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Since the first case in Indonesia, the government has directly handled it by implementing Large-Scale Social Restrictions (PSBB) from March 2020 to May 2020. In it, it is regulated to limit activities and stop mass activities. One of them is the city of Banjarmasin due to the highest number of cases in Banjarmasin 70 percent of the Covid-19 cases are in the city of Banjarmasin, making the city of Banjarmasin a red zone which has a very significant impact on all sectors. As the city center, the city of Banjarmasin makes the industrial, trade, service and tourism sectors the mainstay of the economy. Of course, this sector requires a large number of people, so this sector is greatly affected by the social distancing regulations. Since the onset of COVID-19, economic growth in Gudang Hirang Village has experienced a very significant decline. If more and more households lose their jobs, the more households will lose their income, which will have an impact on household consumption. When household income decreases, household consumption also decreases. One of the problems we encountered was mainly in terms of the economy. Very minimal income by relying on agricultural products causes the local economy to be less stable, so that the use of agricultural products, namely rice, to improve skills and the economic value of rice is increasing. By making preparations of rice soap and green tea leaf extract, the community becomes innovative by utilizing natural ingredients in the village to improve the economy of the people of Gudang Hirang Village RT 05. Together with representatives of residents who have previously received education on the efficacy of the ingredients used to make liquid soap from rice and green tea leaf extract which can treat itching. Making liquid soap from rice and green tea leaf extract to improve the economy and overcome skin itching was seen to be useful for cadres because they could understand and be able to participate in making liquid soap, which can be seen from the results of the questionnaire before and after the training on making liquid soap from rice and green tea leaf extract. The increase in the success percentage of the program was from 20.8% to 91.30% Sejak kasus pertama di Indonesia, pemerintah langsung melakukan penanganan dengan menerapkan Pembatasan Sosial Berskala Besar (PSBB) dari Maret 2020 hingga Mei 2020. Didalamnya diatur agar pembatasan aktivitas dan dihentikan kegiatan yang bersifat massal. Salah satunya kota Banjarmasin akibat jumlah kasus terbanyak di Banjarmasin 70 persen dari kasus covid-19 berada di kota Banjarmasin, membuat kota Banjarmasin menjadi zona merah yang berdampak sangat signifikan kepada semua sektor. Sebagai pusat kota, kota Banjarmasin menjadikan sektor industri, perdagangan, jasa dan pariwisata sebagai andalan perekonomian. Tentunya, sektor ini yang terdampak akibat adanya peraturan social distancing. Semenjak adanya covid-19, pertumbuhan ekonomi di Desa Gudang Hirang mengalami penurunan yang sangat signifikan. Semakin banyak rumah tangga kehilangan pekerjaan, maka maka semakin banyak kehilangan pendapatan sehingga berdampak kepada konsumsi rumah tangga. Konsumsi rumah tangga juga ikut menurun. Salah satu permasalahan yang kami dapati terutama dalam hal perekonomian. Pendapatan yang sangat minim dengan mengandalkan hasil pertanian menyebabkan perekonomian masyarakat daerah kurang stabil, sehingga pemanfaatan bahan hasil pertanian yaitu beras untuk meningkatkan keterampilan dan nilai ekonomi menjadi semakin naik. Dengan membuat sediaan sabun beras dan ekstrak daun teh hijau masyarakat menjadi inovatif dengan memanfaatkan bahan alam yang ada di desa untuk meningkatkan perekonomian masyarakat Desa Gudang Hirang RT 05. Bersama perwakilan warga yang sebelumnya sudah mendapatkan edukasi khasiat dari bahan yang digunakan untuk pembuatan sabun cair dari beras dan ekstrak daun teh hijau yang dapat mengatasi gatal-gatal. Pembuatan sabun cair dari beras dan ekstrak daun teh hijau untuk meningkatkan perekonomian dan mengatasi penyakit gatal-gatal pada kulit terlihat kebermanfaatannya oleh kader karena dapat memahami dan mampu ikut serta dalam pembuatan sabun cair tersebut, yang dapat dilihat dari hasil kuesioner sebelum dan sesudah diadakannya pelatihan pembuatan sabun cair dari beras dan ekstrak daun teh hijau. Kenaikan persentase keberhasilan dari program tersebut adalah dari 20,8% menjadi 91,30%.

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49

Prokopov, S. "J. S. Bach and G. F. Handel’s works performed by the choir of the Kharkiv National Kotlyarevsky University of Arts students." Problems of Interaction Between Arts, Pedagogy and the Theory and Practice of Education 52, no. 52 (October 3, 2019): 22–37. http://dx.doi.org/10.34064/khnum1-52.02.

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Background. In Ukraine both musicologists and performers (in particular the choirs conducted by well-known choirmasters) do much for the further development of the home Bach studies. For instance, the direction of the ‘choral bahhiana’ was actively developed by the leading choirmasters of that time professor M. Berdennikov (Kiev), Y. Kulik (Kharkiv) in the 60’s and 70’s. It is known that future students of the choral conducting departments first learn the choral heritage of J. S. Bach and G. F. Handel, as a rule, at the piano lessons at children musical schools and secondary schools. Unfortunately, their choral works aren’t often sounded today in the concert halls of musical academies and universities of arts. This music seemed to move from the concert stage to the classrooms. Analysis of publications according the topic. Among the researches that highlight the problems of the style of the sacred works of J. S. Bach and G. F. Handel, it is necessary to point out the fundamental studies of I. Givental and L. Gingold, M. Druskin, T. Livanova, V. Protopopov, A. Schweitzer, articles of modern authors by K. Berdennikova, N. Inutochkina, Y. Lyashenko, V. Semenuk, G. Skobtsova. However, the questions of the specifics of choral vocal technique remain, as a rule, outside the attention of scholars and they constitute the topic’s relevance of the article. Methods. The usage of the historical method contributed to the research of the educational choral performance at the present stage. It is involved structural-functional and intonational methods for establishing dramatic works’ features and concretization of their spiritual content. The comparative method is used to determine the differences between vocal style of J. S. Bach and G. F. Handel’s works and the technique of working with them. Objectives. The main goal is systematization of theoretical and practical observations with the performance of J. S. Bach and G. F. Handel’s choral works by the choir of the Kharkiv National Kotlyarevsky University of Arts students. The article is devoted to highlighting the problems of the performing process and the specifics of the choir practice of students with compositions by J. S. Bach (Cantata No. 140, ‘Wachet auf, ruft uns die Stimme’ and Magnificat) G. F. Handel (Dettingen Te Deum in D major, HWV 283). Results. The holding of the 22nd International Music Festival “Kharkiv Assemblies” devoted to the J. S. Bach and G. F. Handel’s oeuvre in 2015 was a significant event not only for Kharkiv but also the whole Ukraine’s musical life. The choir of the Kharkiv National Kotlyarevsky University of Arts students traditionally participated in it as in previous years (art director – Honored Art Worker of Ukraine, professor S. Prokopov, choirmasters – laureate of the all-Ukrainian competition H. Savelyeva, award winner of the all-Ukrainian competition O. Fartushka). The choir performed Magnificat and Cantata No. 140 by J. S. Bach ‘Wachet auf, ruft uns die Stimme’, fragments from the Dettingen Te Deum in D major, HWV 283 by G. F. Handel (the last two works are Kharkiv premieres). The work with them took place in short order and so it caused of some vocal technique difficulties and the problems of performative concept and performative style. Complaxities were intensified by the lack of necessary acoustic accumulation and the practical experience of performing the music of the Baroque by many young choirmasters, members of the choir group. The importance of studying the musical heritage of composers of genius in order to make a conductor-choirmaster personality is emphasized in the article. The main difficulties of learning choral scores due to the lack of performing experience, certain acoustic accumulation of choral music of the late baroque period which students of choral conducting specialization have. The approximation to the true understanding of the performing style of choral music by J. S. Bach and G. F. Handel may be provided with conditions of a thorough in-depth studying their works. The main tasks of the performative choices are described: appreciation of the entire depth of the spiritual content of J. S. Bach’s and G. F. Handel’s music by young performers, the correlation between vocal and instrumental principles, rational and emotional ones. One of the main tasks of the choir practice of students with J. S. Bach’s cantata No. 140 «Watchet auf, ruft uns die Stimme» was an adequate presentation of composer’s style. The composer treats the human voice as equal to the orchestra. Therefore, the vocal-instrumental nature of Bach’s choral style needs another way of sound-building, a greater unity of voices than our home choral music needs. They consider specific methods and techniques of work on such executive factors as tempo-rhythm, strokes. The questions of choral vocal technique, in particular, vocal intonation (significance of timbre expression, usage of different types of respiration, clear diction, active articulation) are raised. J. S. Bach’s interpretation of voice as an instrument, demands from performers a great deal of its mobility, almost virtuosity, especially in contrapuntal sections. As for the vocal style of G. F. Handel, the influence of the operatic style, which is felt in his oratorios and cantatas is emphasized. Conclusions. The choir practice of students and performing by the student choir of German composers’ genius works, the communication of young performers with outstanding conductors, singers (including foreign ones) became for them the true school of craftsmanship, promoted the professional growth of the choir group, revealed its new performance capabilities. Choral music of J. S. Bach and G. F. Handel should move from the educational audiences of universities and academies to the specific halls. The works of genius need to include in student choral groups’ repertoire.

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Majidnia, Zohreh, Ani Idris, and Peiman Valipour. "Evaluation of Antibacterial Properties of Leather Treated with Silver Nanoparticles." Jurnal Teknologi 60, no. 1 (February 7, 2013). http://dx.doi.org/10.11113/jt.v60.1433.

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Objektif kajian ini adalah untuk merawat kulit dengan nanopartikel perak untuk membangunkan ciri-ciri antibakteria di kulit. Aktiviti biologi ke atas kasut kulit menyebabkan pertumbuhan bakteria dan menyebabkan bau yang tidak menyenangkan. Nanopartikel perak telah diketahui mempunyai beberapa kesan antibakteria dan telah ditambah kepada minyak yang digunakan dalam langkah pemprosesan kulit. Sedikit nanopartikel perak (6 dan 8%v/v) telah dimasukkan ke dalam minyak dan ciri-ciri antibakteria telah dinilai menggunakan rendaman dan kaedah ujian kapasiti. Larutan bakteria, bersamaan kekeruhan McFarland piawai sebanyak 0.5 telah disediakan untuk staphylococcus aureus dan bakteria Escherichia coli. Hasil kajian menunjukkan bahawa ujian antimikrobial ke atas sampel yang mengandungi nanopartikel perak menunjukkan ciri-ciri antibakteria yang indikasi oleh Piawai Antarabangsa (ISO 22196) kelembutan penggantungan kurang dari 3x108 CFU/ml. Oleh itu kulit yang dirawat dengan nanopartikel perak mempunyai ciri-ciri antibakteria dengan kecenderungan untuk mengurangkan bau-bau tidak menyenangkan. Kata kunci: Kulit; sifat anti-bakteria; nanopartikel; perak The objective of this study is to treat leather with silver nanoparticles so as to develop antibacterial properties in the leather. The biological activity on leather shoes resulted in bacterial growth and caused the unpleasant smell. Silver nanoparticles have been known to possess some antibacterial effects and were added to the oil used in the leather processing step. A small amount of silver nanoparticles (6 and 8%v/v) were added to oil and its antibacterial properties have been evaluated using the immersion and capacity test methods. The bacteria suspension, a turbidity equivalent to a 0.5 McFarland standard was prepared for the S. aureus and E. coli bacteria. Results revealed that antimicrobial tests on samples containing silver nanoparticles showed suitable antibacterial properties indicated by the International Standard (ISO 22196) tenderness of suspension of less than 3x108 CFU/ml. Thus leather treated with silver nanoparticles has antibacterial properties with the tendency to reduce the unpleasant odors. Keywords: Leather; antibacterial properties; nanoparticle, silver

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