Добірка наукової літератури з теми "Legionnaires' disease"

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Статті в журналах з теми "Legionnaires' disease":

1
Sabrià, Miguel, and Magda Campins. "Legionnaires’ Disease." American Journal of Respiratory Medicine 2, no. 3 (June 2003): 235–43. http://dx.doi.org/10.1007/bf03256652.
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2
Fallon, R. J. "LEGIONNAIRES' DISEASE." Lancet 332, no. 8603 (July 1988): 167. http://dx.doi.org/10.1016/s0140-6736(88)90722-2.
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3
Phillips, Steven J., Robert H. Zeff, and Dan Gervich. "Legionnaires' Disease." Annals of Thoracic Surgery 44, no. 5 (November 1987): 564. http://dx.doi.org/10.1016/s0003-4975(10)62132-7.
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4
Yu, Victor L. "Legionnaires' Disease." Annals of Thoracic Surgery 44, no. 5 (November 1987): 564. http://dx.doi.org/10.1016/s0003-4975(10)62133-9.
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5
Evenson, Laurie Jane. "Legionnaires’ disease." Primary Care Update for OB/GYNS 5, no. 6 (November 1998): 286–89. http://dx.doi.org/10.1016/s1068-607x(98)00165-6.
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6
Larkin, Marilynn. "Legionnaires' disease." Lancet Infectious Diseases 5, no. 4 (April 2005): 206. http://dx.doi.org/10.1016/s1473-3099(05)70048-7.
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7
Cunha, Burke A., Almudena Burillo, and Emilio Bouza. "Legionnaires' disease." Lancet 387, no. 10016 (January 2016): 376–85. http://dx.doi.org/10.1016/s0140-6736(15)60078-2.
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8
Berry, John. "Legionnaires' disease." Facilities 3, no. 7 (July 1985): 13–14. http://dx.doi.org/10.1108/eb006338.
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9
Brundrett, G. W. "Legionnaires’ disease." Batiment International, Building Research and Practice 17, no. 2 (March 1989): 96–107. http://dx.doi.org/10.1080/01823328908726949.
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10
Roig, Jorge, Christian Domingo, and Jose Morera. "Legionnaires’ Disease." Chest 105, no. 6 (June 1994): 1817–25. http://dx.doi.org/10.1378/chest.105.6.1817.
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Дисертації з теми "Legionnaires' disease":

1
De, Goveia C. "Legionella infections : a review of the literature and a prospective serological study of the incidence of Legionnaires disease at Groote Schuur Hospital." Master Thesis, University of Cape Town, 1989. http://hdl.handle.net/11427/25585.
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A prospective study of patients with pneumonia admitted to Groote Schuur Hospital took place over a one-year period in an attempt to assess the incidence of legionella pneumonia. Acute and convalescent serum samples were obtained from 113 patients. Eight patients (7,1%) showed a fourfold rise in antibody titre against Legionella pneumophila group 1 antigen by indirect immunofluorescent test (IFAT). The findings suggest that legionella pneumonia, although not common, should be considered in the aetiology of pneumonia at Groote Schuur Hospital. The results are presented and a review of the literature is undertaken.
2
Sakamoto, Ryota. "Is driving a car a risk for Legionnaires' disease?" DAM, Kyoto University, 2009. http://hdl.handle.net/2433/126450.
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3
Bhopal, Rajinder Singh. "Geographic variation in the incidence of Legionnaires' disease in Scotland." Electronic Thesis or Dissertation, University of Edinburgh, 1991. http://hdl.handle.net/1842/26329.
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The major sources of infection for Legionnaire's Disease, identified by study of outbreaks, are hot water systems and cooling towers. However, most cases are not part of outbreaks and, for these, the source of infection is rarely traced. The principal aim of this study was to help understand the source of non-outbreak infection by examining the epidemiology of the disease in Scotland. Of the recognized cases which met the study case-definition, 366 were ill between 1978 to 1986 giving a mean annual incidence rate of 7.9 per million. The annual incidence varied in Scotland (range 3.1 to 20.2) and within health boards. Geographical variations were demonstrated by health board, by city and within cities, particularly for non-travel infection. For example, the cumulative incidence rate per million for non-travel, non-outbreak disease in Greater Glasgow Health Board (GGHB) was 130 compared to 45 for the whole of Scotland, and 11, 33 and 50 in Tayside, Lanarkshire and Lothian Health Boards respectively. Of 16 postcode sectors with a high incidence of disease in Scotland, 14 were in GGHB. In GGHB, the residence of non-travel, non-outbreakcases (but not of travel-related ones) was clustered in central areas. Previously unrecognised clustering was also found in other health boards. These variations were not fully explained by differences in the population's exposure to diagnostic tests, as indicated by the number of serology tests requested by Scottish hospitals; the diagnostic service and approach of bacteriology laboratories; and the approach of hospital consultants to the diagnosis of Legionnaires' Disease. Differences in host susceptibility, as reflected by socio-economic status and the incidence of other respiratory disease, were small and did not explain the variation. In the City of Glasgow, many cooling towers were not maintained in accord with recommendations and posed a theoretical risk of infection. The location of residence of non-travel cases was associated with the location of premises with cooling towers, the incidence of non-travel Legionnaires' Disease being more than three times higher in areas of Glasgow within 0.5 kilometres of a cooling tower than in areas more than one kilometre away. The best explanation for these observations is that cooling towers were a major source of non-travel, non-outbreak infection. Hence, for the investigation and prevention of such infection, the emphasis should be on cooling tower maintenance. Close surveillance of apparently sporadic disease is recommended as the basis for disease control and future research.
4
Fry, Norman Kenneth. "Analysis of the ribosomal RNA genes of the family Legionellaceae for classification and identification." Electronic Thesis or Dissertation, London School of Hygiene and Tropical Medicine (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315280.
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Boswell, Timothy Charles John. "The serological crossreaction between legionella and campylobacter." Electronic Thesis or Dissertation, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267616.
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6
Ricketts, Katherine. "The influence of environmental factors on sporadic cases of Legionnaires disease in England and Wales." Electronic Thesis or Dissertation, London School of Hygiene and Tropical Medicine (University of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549779.
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7
James, Brian William. "Nutrient availability modulating physiology and pathogenicity of Legionella pneumophila." Electronic Thesis or Dissertation, Open University, 1997. http://oro.open.ac.uk/57693/.
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A virulent strain of Legionella pneumophila serogroup 1 was established in continuous culture under defined iron-replete conditions at pH 6.9. Iron-limitation and extremes of pH (6.0 and 7.8) influenced the growth and metabolism of L. pneumophila, as manifested by increased metabolic activity, impaired energy coupling, and altered metabolic fluxes. In particular, the physiological versatility of L. pneumophila was demonstrated by a significant decrease in the iron content of biomass (6-fold increase in Yiron), coupled with reduced metabolic efficiency (Y, on), in response to iron-limited growth. Iron limitation promoted the accumulation of significant intracellular reserves of poly- ß-hydroxybutyrate (16 % cell dry wt.), which supported long-term survival of L. pneumophila under starvation conditions. Expression of the important pathogenicity factor, the zinc metalloprotease, was regulated by iron availability. Common iron acquisition mechanisms, such as siderophores and transferrin receptors, were not elaborated by iron-limited cells. However, human transferrin was identified as a potential iron source for L. pneumophila, with the zinc metalloprotease mediating transferrin digestion and possibly iron acquisition. Iron-limitation and extremes of pH also influenced cellular morphology and the surface properties of L. pneumophila, promoting the formation of uniform cultures of short rod-shaped bacteria, with altered fatty acid, phospholipid and protein composition. In addition to morphological and physiological adaptation, iron limitation had a significant effect on the virulence of L. pneumophila. Iron-replete cells grown at pH 6.9 and 6.0 were highly virulent in a guinea pig model. However, the virulence of L. pneumophila was significantly attenuated (P < 0.05) in response to iron-limited growth. This phenomenon was reversible, and correlated with reduced phagocytosis and / or reduced intracellular survival following infection. Decreasing the pH of iron-limited cultures to 6.0 did not stimulate recovery of culture virulence. Therefore, this study clearly demonstrates that environmental stresses, including iron limitation and extremes of pH, play an important role in modulating the physiology and virulence of L. pneumophila, inducing the expression of distinct phenotypes differing in their ability to persist in nature and cause infection.
8
Mentasti, M. "Implementation of molecular techniques in the diagnosis of Legionnaires' disease and in the investigation of legionella outbreaks." Electronic Thesis or Dissertation, University of Westminster, 2016. https://westminsterresearch.westminster.ac.uk/item/9z94y/implementation-of-molecular-techniques-in-the-diagnosis-of-legionnaires-disease-and-in-the-investigation-of-legionella-outbreaks.
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Background. Legionnaires’ Disease (LD) is a mild to severe, potentially lethal, respiratory syndrome caused by members of the Legionella genus, in particular L. pneumophila serogroup (sg) 1 alone causes about 95% of culture confirmed cases. The infection is usually acquired by inhalation of aerosols originating from contaminated fresh water sources, consequently typing of both clinical and environmental isolates is crucial to rapidly identify the possible source and prevent further cases. Legionellae are difficult to isolate by culture, moreover as respiratory samples are not available for up to 65% patients, alternative techniques are needed to diagnose LD and maximise the amount of typing data that can be obtained to aid investigations. Urinary antigen detection and serology provide very limited information regarding the infecting strain, while the advent of PCR and Sanger sequencing has allowed reliable diagnostic and typing methods to be introduced. Objectives. The aim of this study was to improve existing diagnostic and typing molecular assays, and to develop new ones to further standardise diagnostic and typing procedures across members of the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Legionella Infections (ESGLI). Utility of the assays was assessed in both routine and outbreak scenarios. Methods. A wide range of both in silico and in vitro experiments were used to design and validate specific oligonucleotides to improve detection and typing of L. pneumophila. Genomic DNA was manually extracted and prepared for Whole Genome Sequencing (WGS) using Illumina platforms. A bioinformatic approach was used to design a WGS based typing scheme and decipher the evolution of L. pneumophila sg1 Sequence Type (ST) 47, a major disease-causing strain. Results. A real-time PCR detecting L. pneumophila and sg1 specific targets was validated with international colleagues and made available to ESGLI members. Sequence based typing was improved and expanded, and specific typing guidelines produced. A 50 gene core-genome MLST was identified as the best approach to improve the current typing method. ST47 was shown to be a ‘chimera’ between ST109 and ST62, and a specific real-time PCR was designed to detect this strain. Conclusions. The results of this study allowed researchers to obtain faster and more accurate diagnosis of LD, and L. pneumophila typing data from both isolates and primary samples. A metagenomics approach is presently under evaluation to obtain typing results by WGS directly from clinical and environmental samples.
9
Eriksson, Rebecca. "Legionella i kyltorn : Enkätundersökning gällande kommuners och länsstyrelsers tillsyn på kyltorn och behovet av ökad prioritering." Student thesis, Umeå universitet, Institutionen för ekologi, miljö och geovetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-153228.
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If cooling towers are poorly maintained there is a risk of microbial growth such as Legionella which in turn might spread via aerosols and infect humans. This may lead to an outbreak of legionnaires’ disease. The purpose of this study was to highlight the risks of Legionella and cooling towers along with investigating the legal responsibility of businesses and supervision authorities in this regard. The study also investigated whether business should be obligated to register their cooling towers at supervising authorities. The study was partly based on a survey which was sent to Sweden’s 290 municipalities and 21 county administration boards to investigate their knowledge regarding Legionella and cooling towers and if they had inventoried which of their facilities that uses cooling towers. The results of the survey showed that 16% of the municipalities and none of the county administration board had inventoried which of their facilities that uses cooling towers. Half of the municipalities do not have any knowledge if any of their facilities uses cooling towers. Moreover, 45% of the municipalities and 30% of the county administration boards consider that business should register their cooling towers. The results showed that many of Sweden’s municipalities and county administration boards have shortcomings in their knowledge and supervision. Legislation and priorities need to be assessed and regulatory guidance from the Public Health Agency of Sweden is necessary for future progress.
10
CHANSIGAUD, GUENNOC CATHERINE. "Legionelloses et sida : revue de litterature a propos de deux observations." Lyon 1, 1993. http://www.theses.fr/1993LYO1M239.
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Книги з теми "Legionnaires' disease":

1
Zonderman, Jon. Legionnaires' disease. Philadelphia: Chelsea House Publishers, 2005.
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2
executive, Health and safety. Legionnaires' disease. London: H.M.S.O., 1987.
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3
Biocides, Great Britain Expert Advisory Committee on. Report of the Expert Advisory Committee on Biocides. London: H.M.S.O., 1989.
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4
Brundrett, G. W. Engineering aspects of legionnaires disease. Chester: Electricity Council Research Centre, 1986.
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5
Rosa, Frank. Legionnaires' disease: Prevention and control. Troy, Mich: Business News Pub., 1993.
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6
Uzel, Atac. Legionella pneumophila: From environment to disease. Hauppauge, N.Y: Nova Science Pub., 2010.
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7
Baxter, David. Legionnaires disease: A comprehensive description & contemporary bibliography. Manchester: University of Manchester, 1985.
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8
Hodgson, James F. Legionnaires' disease: Good practice guide for plumbers. Hornchurch: Institute of Plumbing, 1990.
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9
Baxter, David. Legionnaires disease: A comprehensive description & contemporary bibliography. Manchester [Lancashire]: University of Manchester, Dept. of Community Medicine, Unit for Continuing Education, 1985.
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10
Baxter, David. Legionnaires disease: A comprehensive description and contemporary bibliography. Manchester: Unit forContinuing Education, Department of Community Medicine, University of Manchester, 1985.
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Частини книг з теми "Legionnaires' disease":

1
Roig, J., M. Sabria, and X. Castella. "Legionnaires’ Disease." In Infectious Diseases in Critical Care, 404–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-34406-3_37.
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2
Kreutner, A. Karen. "Legionnaires’ Disease." In Principles of Medical Therapy in Pregnancy, 480–81. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2415-7_64.
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3
Jia, Cuiyu, Dawei Zhao, and Jianan Yu. "Legionnaires’ Disease." In Radiology of Infectious Diseases: Volume 2, 121–30. Dordrecht: Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-017-9876-1_12.
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4
Cianciotto, Nicholas P., Hubert Hilbi, and Carmen Buchrieser. "Legionnaires’ Disease." In The Prokaryotes, 147–217. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-30144-5_94.
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Lucas, Claressa E., and Barry S. Fields. "Legionellaeand Legionnaires' Disease." In Manual of Environmental Microbiology, 3.2.9–1—3.2.9–13. Washington, DC, USA: ASM Press, 2015. http://dx.doi.org/10.1128/9781555818821.ch3.2.9.
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6
Roig, Jorge, and Jordi Rello. "Treatment of Legionnaires' Disease." In Legionella, 8–14. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555815660.ch02.
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7
Brown, Andrew S., Ian R. van Driel, and Elizabeth L. Hartland. "Mouse Models of Legionnaires’ Disease." In Current Topics in Microbiology and Immunology, 271–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/82_2013_349.
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Berrington, William R., and Thomas R. Hawn. "Human Susceptibility to Legionnaires’ Disease." In Methods in Molecular Biology, 541–51. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-161-5_33.
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Joseph, Carol. "Surveillance of Legionnaires' Disease in Europe." In Legionella, 311–17. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555817985.ch62.
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McDade, Joseph E. "Legionnaires' Disease 25 Years Later: Lessons Learned." In Legionella, 1–10. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555817985.ch1.
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Тези доповідей конференцій з теми "Legionnaires' disease":

1
Muscedere, D., S. Sahni, Y. Malyshev, G. K. Upadhya, and R. Cofsky. "Making It Mental - Neurological Manifestations of Legionnaires’ Disease." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3691.
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2
Cysneiros, Ana, Francisca Lopes, Joao Carvalho, Patricia Dionisio, Christine Costa, Bruno Von Amann, Ana Dias, et al. "Legionella score performance under an outbreak of Legionnaires' disease." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa2576.
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3
Mengiste, H. A., M. Jindal, Y. Gebrekidan, and A. Mehari. "A Case of Legionnaires' Disease Associated with Massive Gastrointestinal Bleeding." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6896.
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Branco, Joana, Carlos Macedo, Nelson Marçal, Ana Alves, Catarina Pissarra, and Paula Rosa. "Pneumology outpatient clinic's role during an outbreak of Legionnaires' disease." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa2582.
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5
Saad eldin, M., M. Alhamaydeh, U. Sana Ullah, and M. Imtiaz. "Severe Legionnaires' Disease with Multi-Systemorgan Failure Responding to Triple Antibiotic Therapy." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6904.
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Kumar, D., D. Kumar, Z. Khan, and M. Bachan. "A Rare Case of Rhabdomyolysis and Renal Failure Secondary to Legionnaires Disease." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3907.
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Brodhun, B., K. Prahm, C. Lück, W. Haas, and U. Buchholz. "Reiseassoziierte Fälle von Legionärskrankheit – Teilnahme Deutschlands am European Legionnaires' Disease Surveillance Network (ELDSNet)." In Der Öffentliche Gesundheitsdienst: Mitten in der Gesellschaft. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1679258.
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Jahn, HJ, B. Brodhun, W. Haas, and U. Buchholz. "Legionnaires' Disease in Germany: trends and seasonal variations by exposure category; 2001 – 2016." In Gemeinsam forschen – gemeinsam handeln. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1605852.
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Torras, J. A., R. Thachil, A. Toor, and M. Krishnamurthy. "Why Continuous Positive Airway Pressure Device Care Is Important - A Tale of Legionnaires' Disease." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3911.
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10
Dias, Ana, Patrícia Dionísio, Francisca Lopes, Christine Costa, João Carvalho, Gustavo Carvalho, Ana Cysneiros, et al. "Clinical presentation of Legionnaires' disease during an outbreak: The typical presentation of an atypical pathogen." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa2589.
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Звіти організацій з теми "Legionnaires' disease":

1
Tyndall, R. L., S. W. Christensen, and J. A. Solomon. Legionnaires' disease bacteria in power plant cooling systems: Phase 2. Office of Scientific and Technical Information (OSTI), April 1985. http://dx.doi.org/10.2172/5732566.
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2
Oster, Emily. Does Disease Cause Vaccination? Disease Outbreaks and Vaccination Response. Cambridge, MA: National Bureau of Economic Research, July 2016. http://dx.doi.org/10.3386/w22464.
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Evans, Celia A., Jennifer A. Lucas, and Mark J. Twery. Beech Bark Disease: Proceedings of the Beech Bark Disease Symposium. Newtown Square, PA: U.S. Department of Agriculture, Forest Service, Northeastern Research Station, 2005. http://dx.doi.org/10.2737/ne-gtr-331.
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Kostoff, Ronald N. Literature-Related Discovery: Common Factors for Parkinson's Disease and Crohn's Disease. Fort Belvoir, VA: Defense Technical Information Center, January 2010. http://dx.doi.org/10.21236/ada525269.
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Somerville, Shauna C. Powdery Mildew Disease Resistance. Office of Scientific and Technical Information (OSTI), August 2010. http://dx.doi.org/10.2172/1123169.
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Pellegrino, Bruno, and Luigi Zingales. Diagnosing the Italian Disease. Cambridge, MA: National Bureau of Economic Research, October 2017. http://dx.doi.org/10.3386/w23964.
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De Jong, Marla J., and Debra K. Moser. Anxiety and Heart Disease. Fort Belvoir, VA: Defense Technical Information Center, January 2003. http://dx.doi.org/10.21236/ada420275.
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Bloom, David, David Canning, and Günther Fink. Disease and Development Revisited. Cambridge, MA: National Bureau of Economic Research, July 2009. http://dx.doi.org/10.3386/w15137.
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Licht, Mark A., and Wayne B. Roush. Insects and Disease Update. Ames: Iowa State University, Digital Repository, 2010. http://dx.doi.org/10.31274/farmprogressreports-180814-112.
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Licht, Mark A., Joel L. DeJong, and Wayne B. Roush. Insects and Disease Update. Ames: Iowa State University, Digital Repository, 2011. http://dx.doi.org/10.31274/farmprogressreports-180814-1248.
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