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1

Kurkin, V. A., and T. K. Ryazanova. "Current aspects of Quality Control and Standardization of <I>Eleutherococcus senticosus</I> Medicines." Drug development & registration 11, no. 3 (2022): 152–61. http://dx.doi.org/10.33380/2305-2066-2022-11-3-152-161.

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Анотація:
Introduction. Nowadays, herbal medicines are becoming more and more popular. In this regard, herbal medicinal preparations based on rhizomes and roots of Eleutherococcus senticosus (Rupr. &amp; Maxim.) Maxim., syn. Acanthopanax senticosus (Rupr. &amp; Maxim.) Harms, are of particular interest. Its have an adaptogenic, immunomodulatory effects mainly due to the presence of phenyl propane compounds: eleutherosides B, D, E, E1. The current pharmacopeial monographs FS.2.5.0053.15 "Eleutherococcus senticosus rhizomes and roots" and FS.3.4.0009.18 "Eleutherococcus senticosus rhizomes and roots liqui
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2

Syrov, V., L. Pulatova, and O. Kamalov. "INCREASING THE ADAPTATION POTENTIAL OF THE ORGANISM BASED ON THE ANTITOXIC EFFECT OF EXUMIDE." Scientific heritage, no. 160 (May 8, 2025): 12–17. https://doi.org/10.5281/zenodo.15362501.

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The paper studies the issues of practical application of exumid, which is a total extractive preparation containing a sum of phytoecdysteroids and iridoid glycosides isolated from an endemic plant of Uzbekistan. The increase in the antitoxic capabilities of the animal organism under the influence of exumid was also quite clearly revealed in the tissue hypoxia model. It was shown that in all the experiments conducted, Exumid exhibited a more pronounced positive effect than a well-known herbal medicinal product &ndash; liquid Eleutherococcus extract.
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3

Ondrejovič, Miroslav, Daniela Chmelová, and Tibor Maliar. "Optimization of the Antioxidant Extraction from Eleutherococcus Senticosus Roots by Response Surface Methodology." Nova Biotechnologica et Chimica 12, no. 1 (2013): 30–38. http://dx.doi.org/10.2478/nbec-2013-0003.

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Анотація:
Abstract Eleutherococcus senticosus is known as adaptogen with benefits in general health promotion. The aim of this study was to investigate the effect of major extraction parameters on extraction yield of antioxidants measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity. Secondly, content of total polyphenols was evaluated. Optimal conditions of the extraction were processed by response surface methodology. The independent variables of extraction were proposed as temperature, solid-liquid ratio and solvent composition. For the optimal antioxidant extraction, E. sentic
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4

Bocharova, O. A., R. V. Karpova, E. V. Bocharov, et al. "LFA-1, MAC-1 LEUKOCITE INTEGRINS – TARGET FOR TUMOUR IMMUNITY MAGNIFICATION." Russian Journal of Biotherapy 19, no. 1 (2020): 53–58. http://dx.doi.org/10.17650/1726-9784-2019-19-1-53-58.

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Анотація:
The aim of this investigation was to evaluate the expression of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) β2 integrins on blood cells in CBA mice in ontogenesis as well as under the dry extract of multifitoadaptogen administration during the first month of postnatal development.Materials and methods. The study was carried out on CBA male mice (CBA/LacY). The experimental mice received 0.3 % dry multiphytoadaptogene extract water-solution during the first month of life (preventive administration). Preparation was produced by a desiccation technology of forty medical herbs (including Panax ginse
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5

Matsiuk, O. D., L. I. Vyshnevska, and A. V. Buhai. "Overview of the range of medicinal extracts at the pharmaceutical market of Ukraine." Social Pharmacy in Health Care 7, no. 3 (2021): 31–40. http://dx.doi.org/10.24959/sphhcj.21.231.

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Анотація:
Aim. To study the range of medicinal extracts at the pharmaceutical market of Ukraine as of 2020 in order to determine the feasibility of developing a new medicinal product based on them.Materials and methods. The bibliosemantic, analytical, logical research methods were used to analyze the literature sources; the analytical analysis was applied to study the segment of the domestic pharmaceutical market regarding the range of medicinal extracts as of 2020. Thus, their composition, distribution by the aggregate state, forms of production and country of origin, harmonization with the Ph. Eur. we
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6

Kimak, H. B., та L. V. Tarnavska. "EVALUATION OF INFLUENCE OF THE UNITED COMPLEX AND SURGICAL TREATMENT ON SOME INDEXES OF CARBOHYDRATE EXCHANGE FOR PATIENTS ON GENERALIZED PERIODONTITIS І-ІІ DEGREE OF DEVELOPMENT". Ukrainian Dental Almanac, № 2 (29 червня 2021): 15–18. http://dx.doi.org/10.31718/2409-0255.2.2021.03.

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The dynamics of the inflammatory process in the periodontium, its generalization and chronization are determined not only by the composition of the microflora, but also by the state of the protective reactions of the organism (the pro-atherogenic spectrum of lipids and the disturbance of the carbohydrate metabolism) and the reactivity of the immune system in response to the pathogenic factor.&#x0D; Purpose of the study. The study of changes in the parameters of carbohydrate metabolism in the oral fluid of patients with generalized periodontitis (GP), before and during the different terms after
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7

Палагина, М. В., Е. О. Рочин, М. В. Марченок, and Е. И. Черевач. "The Use of Wild Plants of the Far East with Adaptogenic and Antioxidant Properties in Food Production." Food processing industry, no. 8 (August 2, 2023): 87–90. http://dx.doi.org/10.52653/ppi.2023.8.8.016.

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Анотація:
в Приморском и Хабаровском краях Дальнего Востока России. Из собранного сырья готовили водно-спиртовые экстракты, в которых методом высокоэффективной жидкостной хроматографии определяли содержание флавоноидов. Показано, что все образцы растительных экстрактов содержали значительные концентрации индивидуальных флавоноидов – рутина и кверцетина: от 31 до 54 мг/100 мл. При этом содержание полифенолов в экстрактах из стеблей оказалось достоверно выше, чем в экстрактах из корней. Массовую концентрацию органических кислот экстрактов определяли методом капиллярного электрофореза. Были обнаружены аско
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8

Baygildieva, D. I., A. V. Braun, A. N. Stavrianidi, and I. A. Rodin. "Determination of Eleutheroside B and Eleutheroside E in Extracts from Eleutherococcus senticosus by Liquid Chromatography/Mass Spectrometry." Journal of Analytical Chemistry 75, no. 14 (2020): 1832–37. http://dx.doi.org/10.1134/s1061934820140051.

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9

Tolmachev, O., A. Vekovtsev, A. Bykov, and V. Pozniakovskiy. "A NON-ALCOHOLIC BEVERAGE FOR PREVENTION AND COMPREHENSIVE TREATMENT OF POST-TRAUMATIC OSTEOARTHRITIS IN PROFESSIONAL AND AMATEUR SPORT." Human Sport Medicine 20, no. 2 (2020): 116–24. http://dx.doi.org/10.14529/hsm200214.

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Aim. The article aims to develop a non-alcoholic beverage for post-traumatic recovery of the structure and functions of cartilage tissue in professional and amateur athletes. Materials and methods. The materials used were a premix containing aquamin soluble (a natural source of calcium), glucosamine sulfate (a chondroprotector) and herbal components, as well as laboratory and industrial samples of a sports beverage. To assess the quality of the flavor syrup and the finished drink, generally accepted and special research methods were used including spectrophotometry, high performance liquid chr
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10

Bocharov, E. V., O. A. Bocharova, R. V. Karpova, et al. "Immunoadhesive regulation using multiphytoadaptogene for spontaneous hepatocarcinomas prevention." Russian Journal of Biotherapy 17, no. 2 (2018): 78–87. http://dx.doi.org/10.17650/1726-9784-2018-17-2-78-87.

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Анотація:
The purposeof this investigation was to evaluate the efficacy of correcting the LFA-1 and Mac-1 leukocyte integrins expression on peripheral blood cells as well as IL-6 and IL-10 serum levels using liquid form multiphytoadaptogene preventive application for hepatocarcinomas incidence suppression and life-span increase of CBA inbreed mice.Materials and methods.The study was carried out on 439 males of inbred CBA mouse strain (subline CBA/LacY). The experimental mice received 10 % liquid form multiphytoadaptogene complex (MPAC) solution in drinking water during the first month of life including
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11

Chen, Jingnan, Yanping Sun, Sen Li, et al. "LC-MS/MS method for the simultaneous determination of six phenolic acids in rat plasma and hypoglycemic effects in normal and T2DM rats after oral administration of Eleutherococcus senticosus fruits extract." Acta Chromatographica, December 2, 2024. https://doi.org/10.1556/1326.2024.01253.

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Анотація:
AbstractEleutherococcus senticosus (Rupr. &amp; Maxim.) Maxim. fruits (ESF) is a natural health food that has been widely used in traditional medicine. This study aimed to establish and validate a rapid and sensitive method for determining of six phenolic acids in plasma of normal and T2DM rats by ultra-performance liquid chromatography–tandem mass spectrometry (UHPLC-MS/MS). Separation and quantification were performed on a Waters HSS T3 column (100 × 2.1 mm, 1.8 μm) with water (A) and methanol (B). The electrospray ionization (ESI) source was operated in negative ionization mode. Multiple re
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12

Байгильдиева, Д. И., А. В. Браун, А. Н. Ставрианиди та И. А. Родин. "Хроматомасс-спектрометрическое определение Элеутерозида B и Элеутерозида E в адаптогенных экстрактах из растения Eleutherococcus senticosus". Масс-спектрометрия 16, № 4 (2019). https://doi.org/10.25703/ms.2019.16.43.

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Анотація:
Eleutherococcus senticosus (Элеутерококк колючий) растение, обладающее лекарственными свойствами благодаря присутствию в корнях и корневищах гликозидов, названных элеутерозидами А, В и В1, C, D, E, F. В данной работе предложен способ одновременного определения элеутерозида В и элеутерозида Е в сухих пробах корня Eleutherococcus senticosus разных производителей методом высокоэффективной жидкостной хроматографии/масс-спектрометрии в режиме мониторинга выбранных ионных реакций в варианте регистрации отрицательно заряженных ионов, что обеспечило лучшее соотношение сигнал/шум. Для извлечения элеуте
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13

Kvirencova, Jana, Vojtech Hrbek, Monika Tomaniova, and Jana Hajšlova. "Authentication of Panax Ginseng‑Based Herbal Teas Using “Chemical Markers” Strategy." LCGC Europe, July 1, 2022, 20–24. http://dx.doi.org/10.56530/lcgc.eu.ig4675a1.

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Анотація:
This article describes the method development involved in the authentication of nutraceuticals, particularly those containing Panax ginseng, which is popular because of possible positive effects on human health. For this purpose, an analytical strategy based on a metabolomic approach was chosen. The aqueous methanolic extracts were analyzed using ultrahigh-performance liquid chromatography coupled to high-resolution mass spectrometry (UHPLC–HRMS). Generated data were processed by advanced statistical methods that enabled the specific markers for Panax ginseng and other plants that can be used
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14

Milentyeva, Irina, Violeta Le, Oksana Kozlova, et al. "Secondary metabolites in in vitro cultures of Siberian medicinal plants: Content, antioxidant properties, and antimicrobial characteristics." Foods and Raw Materials, April 20, 2021, 153–63. http://dx.doi.org/10.21603/2308-4057-2021-1-153-163.

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Анотація:
Introduction. Wild-crafting leads to the local extinction of many medicinal plants that are rich in phenolic substances. In vitro cultivation of cells and organs of higher plants can be the optimal solution to this problem. The research objective was to study the biosynthetic activity of in vitro extracts of wild Siberian plants.&#x0D; Study objects and methods. The study featured callus, cell suspension, and hairy root extracts of such Siberian medicinal plants as Eleutherococcus senticosus, Codonopsis pilosula, Platanthera bifolia, and Saposhnikovia divaricata. They were obtained by in vitro
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15

BetaBeat, Blood Sugar. "BetaBeat |#EXCITING NEWS|: BetaBeat Blood Sugar Support Heart & Stimulates Metabolism!" October 7, 2022. https://doi.org/10.5281/zenodo.7155566.

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Анотація:
BetaBeat are blood sugar support supplements. It is an amalgamation of 24 natural and potent plant-based ingredients. Cinnamon and licorice found in this product are considered the best and highly potent traditional ingredients to cure abnormal blood sugar levels Diabetes arises when the cells in your become unable to absorb sugar (glucose) and convert it into fuel as a source of energy for normal bodily functioning. As a result, your bloodstream begins to accumulate additional sugar. Must Read: &ndash; Latest Update &ldquo;BetaBeat Blood Sugar Support Formula&rdquo; is HERE to BANG ON 2022 Be
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