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Дисертації з теми "Lymphocytes Immunological aspects"

Автор: Grafiati

Опубліковано: 4 червня 2021

Оновлено: 28 січня 2023

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1

Elliott, Salenna R. "Lymphocyte expression of costimulator molecules in early life /." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phe466.pdf.

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2

Qin, Gang, and 秦刚. "The immunological roles of human gammadelta T lymphocytes in influenzavirus infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46477354.

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3

Hjorth, Maria. "Immunological profile and aspects of immunotherapy in type 1 diabetes." Doctoral thesis, Linköping : Department of Clinical and Experimental Medicine, Linköping University, 2010. http://www2.bibl.liu.se/liupubl/disp/disp2010/med1161s.pdf.

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4

Arvola, Marie. "Immunological aspects of maternal-foetal interactions in mice." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-4947-6/.

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5

Roufosse, Florence. "Clonal expansion of helper type 2 lymphocytes as a cause of the hypereosiophilic syndrome: clinical and immunological aspects." Doctoral thesis, Universite Libre de Bruxelles, 2001. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211498.

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6

Varelias, Antiopi. "Studies of CD44 variant isoform expression and function on activated human peripheral blood mononuclear cells and in renal transplantation." Title page, summary and contents only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phv293.pdf.

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7

McDonnell, Alison. "The role of dendritic cells in the cross-presentation of tumour antigens." University of Western Australia. School of Medicine and Pharmacology, 2009. http://theses.library.uwa.edu.au/adt-WU2010.0017.

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Анотація:

[Truncated abstract] A paradox exists in tumour immunology whereby progressive tumour growth exists in parallel with an anti-tumour T cell response. This defective T cell response is thought to result from the induction of T cell tolerance and/or tumour induced immunosuppression, which act to inhibit the activation, differentiation and function of tumour-specific CD8+ T cells. Dendritic cells (DCs) are professional antigen presenting cells (APCs) that are critical to the generation of effective CTL; however their function and phenotype is often defective or altered in tumour-bearing hosts, whi

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8

Divekar, Rohit Dilip Zaghouani Habib. "Two aspects of peripheral immune tolerance systemic and mucosal tolerance mechanisms /." Diss., Columbia, Mo. : University of Missouri-Columbia, 2008. http://hdl.handle.net/10355/6868.

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The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on April 1, 2010). Vita. Thesis advisor: Habib Zaghouani. "May 2008" Includes bibliographical references.

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9

Nuttin, Lise. "Etude du rôle des lymphocytes T régulateurs dans la régulation des réponses immunes antitumorales induites par vaccination." Doctoral thesis, Universite Libre de Bruxelles, 2011. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209820.

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Le système immunitaire est capable de rejeter une tumeur, même si l'interaction entre système immun et tumeurs est et reste complexe. Contrôler à long terme la croissance de la tumeur est un challenge, probablement suite à divers mécanismes de tolérance centrale et périphérique. Différentes approches d'immunothérapie du cancer ont été et sont toujours développées. Nous avons, au laboratoire, investigué et démontré, dans le cadre de deux différents modèles tumoraux murins, les capacités thérapeutiques d’une nouvelle stratégie de vaccinations combinées associant des injections de cellules dendri

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10

Dauby, Nicolas. "Réponse des lymphocytes B lors de l'infection primaire au cytomégalovirus humain pendant la grossesse." Doctoral thesis, Universite Libre de Bruxelles, 2015. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209097.

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L'infection par le cytomégalovirus humain (HCMV) est une cause majeure de mortalité chez les patients immunodéprimés et représente la première cause d'infection congénitale. HCMV est un virus complexe qui s'est adapté au système immunitaire humain en développant de multiples mécanismes d'évasion. L'infection primaire à HCMV est associée à une réplication virale prolongée avant l'établissement de la latence. Il a été montré que cette intense réplication lors de la phase initiale de l'infection était associée à une épuisement fonctionnel des lymphocytes T CD4 spécifiques du virus. Alors que les

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11

Coquerelle, Caroline. "Contrôle des réponses immunitaires de type Th1 par les lymphocytes T régulateurs naturels et induits." Doctoral thesis, Universite Libre de Bruxelles, 2008. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210397.

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Depuis leur découverte en 1973 par Steinman et Cohn, le rôle des cellules dendritiques dans l’initiation des réponses immunitaires a largement été documenté. En effet, les cellules dendritiques constituent les cellules présentatrices d’antigènes professionnelles capables de détecter des molécules microbiennes et inflammatoires afin d’activer le système immunitaire. Outre leur implication dans l’induction des réponses immunes, de plus en plus d’études suggèrent que les cellules dendritiques interviennent dans le contrôle des réponses immunitaires via la sécrétion de cytokines anti-inflammatoire

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12

Poulin, Lionel. "Rôles de l'IL-9 dans les mécanismes de rejet d'allogreffe dirigés par les lymphocytes TCDA+ de type Th2." Doctoral thesis, Universite Libre de Bruxelles, 2005. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211038.

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Le rejet d’allogreffe dépend de la reconnaissance d’antigènes d’histocompatibilité étrangers par le système immunitaire du receveur. En l'absence de thérapies immunosuppressives, la réaction inflammatoire éventuelle conduit à la destruction rapide du tissu transplanté. Le rôle critique joué par les lymphocytes T CD4+ dans le rejet aigu d'allogreffe est bien établi. Cependant, les contributions respectives des lymphocytes CD4+ Th1 et Th2 dans la réaction de rejet sont controversées. Alors que le rôle des cellules Th1 dans la pathogénèse du rejet est bien établi, l'hypothèse que les cellules Th2

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13

Hespel, Cindy. "Régulation de la réponse immunitaire adaptative par les cellules dendritiques conventionnelles et inflammatoires." Doctoral thesis, Universite Libre de Bruxelles, 2012. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209702.

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Les cellules dendritiques décrites depuis les années 60 ont instantanément capté l’intérêt des scientifiques qui ont pu mettre en évidence leur rôle indispensable dans l’initiation des réponses immunitaires adaptatives et leur ont attribué le surnom « d’adjuvant naturel ». De manière surprenante, les cellules dendritiques conventionnelles sont aussi indispensables dans le maintien de la tolérance et peuvent présenter naturellement ou acquérir une fonction suppressive. Parmi les mécanismes capables de contrôler les réponses de type Th1, l’enzyme indoléamine 2,3-dioxygénase (IDO) a particulièrem

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14

Endicott, Roger A. "Immunoregulation of T-lymphocyte proliferative activity by alveolar macrophages from mice bearing Lewis lung carcinoma tumors." Virtual Press, 1986. http://liblink.bsu.edu/uhtbin/catkey/458971.

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Анотація:

The immune regulatory abilities of alveolar macrophages from C57B1/6 mice bearing a metastatic variant of Lewis lung carcinoma were determined. During early stages of tumor development, or before tumors metastasized to the lungs, alveolar macrophages did not affect or slightly enhanced T-lymphocyte proliferation; as tumor growth progressed, or following tumor metastasis, alveolar macrophages suppressed the T-cell response. Macrophage suppressor activity was probably not mediated by their production of PGE, since macrophages of tumor-bearing mice secreted less 2 PGE than did macrophages of norm

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15

Xu, Xuequn, and 徐學群. "Longitudinal study of Epstein-barr virus (EBV) - specific CD8 + T lymphocyte development in primary EBV infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B4163407X.

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16

Djamiatun, Kis. "In vitro studies on induction of lymphocyte and cytokine responses to the gut protozoans Giardia lamblia and Giardia muris." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23882.

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In mice infected with 10$ sp4$ Giardia muris cysts, a peak lymphocyte proliferation in the spleen and Peyer's patches in response to Giardia extract occurred during the elimination and latent phases, respectively. This shows that the Peyer's patch cells are more responsive than the spleen to Giardia infection. Th2-type cytokines produced by Peyer's patch cells may play a protective role during the latent and acute phases. Th1-type cytokines may contribute to this production during the elimination phase. Cytokine production in response to Giardia extract in vitro was observed in mice immunized

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17

Elliott, Salenna R. "Lymphocyte expression of costimulator molecules in early life / Salenna R. Elliott." Thesis, 1999. http://hdl.handle.net/2440/19507.

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Bibliography: leaves 170-206.<br>vi, 206 leaves : ill. (some col.) ; 30 cm.<br>In T-dependent antibody responses, costimulator molecules provide contact-medited signals during interactions between T cells and B cells that regulate lymphocyte activation. This study investigated the hypothesis that costimulator molecules are differentially expressed on lymphocytes from neonates and young children compared with adults, contributing to limitations of T-dependent antibody responses in early life. Results suggest that lymphocytes from young children should be able to deliver and respond to costimula

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18

Wang, Yang. "Cytotoxic T lymphocytes in West Nile virus encephalitis : protection and immunopathology." Phd thesis, 2004. http://hdl.handle.net/1885/151680.

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19

Paalangara, Reji Francis. "Development of the capacity of the gut-associated immune system of perinatal lambs to respond to parasitic antigens." Phd thesis, 2000. http://hdl.handle.net/1885/148127.

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20

Govender, Sumentheran Nadarajan. "The effects of high intensity exercise on lymphocyte DNA and antioxidant status in trained athletes." Thesis, 1998. http://hdl.handle.net/10413/7648.

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Apoptosis (programmed cell death) and exercise immunology have been the focus of research for the past five years. Trained athletes are particularly susceptible to a wide variety of viral and bacterial infections and this has been related to oxidative damage which is a mediator of apoptosis. Apoptosis, a normal physiological mechanism has also been implicated in the pathogenesis of a wide-variety of diseases. To date, the link between apoptosis and exercise has not been shown by established methods or ultrastructurally. The objective of the study was t.o determine the effects of a single bout

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21

"Immunoregulatory role of human islet amyloid polypeptide through FoxP3+CD4+CD25+ T regulatory cells." Thesis, 2010. http://library.cuhk.edu.hk/record=b6075044.

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Background. Islet amyloid polypeptide (IAPP, also known as amylin) is a 37-amino acid peptide principally co-secreted with insulin from the beta-cells of the pancreatic islets. Some of the physiological actions of human amylin (hIAPP) include glucose regulation, suppression of appetite and stimulation of renal sodium and water reabsorption. Amylin deficiency and diminished post-prandial amylin response have been reported in advanced stages of type 1 and type 2 diabetes. In autopsy specimens of type 2 diabetes, amyloid is found in 40--90% of cases. During the characterization of islet morpholog

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22

Kesson, Alison M. "T lymphocyte response to flavivirus infections." Phd thesis, 1989. http://hdl.handle.net/1885/143085.

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23

Xu, Zhun 1973. "Cbl-b: its role of expression and regulation in T-lymphocyte activation and ageing." Thesis, 2007. http://hdl.handle.net/2152/3363.

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The aging process is strongly associated with decreased activity in the immune system. Dysregulation of T-lymphocyte function, such as reduced proliferation, is one problem faced by most elder people, which prevents them from successfully dealing with exogenous pathogens. Effective regulation of T-lymphocyte activity depends on the proper and prompt transduction of both positive and negative signals within Tlymphocytes and reflects the balance between positive and negative effects. Decline of positive signaling in aging has been studied and reported, while mechanisms concerning up-regulation o

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24

Blake-Mortimer, Jane Suzanne. "Lymphocytic 5'-ectonucleotidase : a marker of psychological stress-induced immune suppression / Jane Blake-Mortimer." 1996. http://hdl.handle.net/2440/18799.

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Addendum inserted (leaf 170 verso)<br>Some illustrations are on unnumbered leaves.<br>Bibliography: leaves 151-170.<br>xiv, 170, [25] leaves : ill. (some col.) ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Lymphocyte 5'-ectonucleotidase (NT) was selected as a mechanism to explain the phenomenon of stress-induced immunosuppression. The findings indicates that NT is a good marker of stress induced immune suppression and correlates negatively with depression scores such as the Beck Depression Inventory, and psych

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