Добірка наукової літератури з теми "Lyophilized Vials"

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Статті в журналах з теми "Lyophilized Vials"

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Rajesh, Akki* M.Gayatri Ramya M.Hymavathi P.Dinesh Kumar. "DEVELOPMENT, EVALUATION AND STABILITY OF ZOLEDRONIC ACID I.V INJECTION BY LYOPHILIZATION TECHNIQUE." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2042–46. https://doi.org/10.5281/zenodo.834723.

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Анотація:
The objective of the study is to develop a stable lyophilized formulation of Zoledronic acid for injection for better stability and for long term storage. The lyophilized product of all the formulations (F1- F6) prepared were an appearance of white to white Lyophilized cake. mannitol was used with water for injection . The filled vials were loaded into lyophilizer and lyophilized them as per cycle. Different composition of additives was used and the different pH concentrations of 5.7 to 6.7 were adjusted with sodium citrate were tried to formulate the formulation. The pH of all the formulation
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Muzzio, Cristian Rodrigo, Nicolás Gabriel Dini, and Laura Daniela Simionato. "Determination of moisture content in lyophilized mannitol through intact glass vials using NIR micro-spectrometers." Brazilian Journal of Pharmaceutical Sciences 47, no. 2 (2011): 289–97. http://dx.doi.org/10.1590/s1984-82502011000200010.

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Анотація:
Determination of moisture content in lyophilized solids is fundamental to predict quality and stability of freeze-dried products, but conventional methods are time-consuming, invasive and destructive. The aim of this study was to develop and optimize a fast, inexpensive, noninvasive and nondestructive method for determination of moisture content in lyophilized mannitol, based on an NIR micro-spectrometer instead of a conventional NIR spectrometer. Measurements of lyophilized mannitol were performed through the bottom of rotating glass vials by means of a reflectance probe. The root mean standa
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VIÑA-ROMERO, MICAELA M., RUTH RAMOS-DIAZ, IVETTE MOURANI-PADRON, et al. "Extended Stability of Reconstituted Lyophilized Erwinia L-asparaginase in Vials." In Vivo 34, no. 5 (2020): 2419–21. http://dx.doi.org/10.21873/invivo.12055.

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Panda, Sunil Kumar, and Subas Chandra Dinda. "Development of lyophilization cycle for direct thrombin Inhibitor and influence of excipients and process parameter during the cycle." International Current Pharmaceutical Journal 3, no. 5 (2014): 259–64. http://dx.doi.org/10.3329/icpj.v3i5.18533.

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Анотація:
The objective of this study was to develop stable lyophilized product of Bivalirudin, a direct thrombin inhibitor with good reconstitution time, % yield of good vials and cake quality. The % loss of crystallinity was determined by DSC for any crystallographic changes of the bulking agent after freeze drying. The glass transition temperature of 5% w/v of Bivalirudin, 3% w/v of mannitol and 0.03% of sodium acetate was approximately ?31°C and the collapse temperature was approximately -28°C. Tubular vials were found to withstand the thermal transition during freeze drying. Water content was inver
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André, Pascal, Salvatore Cisternino, Fouad Chiadmi, et al. "Stability of Bortezomib 1-mg/mL Solution in Plastic Syringe and Glass Vial." Annals of Pharmacotherapy 39, no. 9 (2005): 1462–66. http://dx.doi.org/10.1345/aph.1e620.

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Анотація:
BACKGROUND: The proteasome inhibitor bortezomib (BTZ), used in antineoplastic chemotherapy, must be diluted in NaCl 0.9% for injection and stored for no more than 3 hours in a syringe or 8 hours in a vial. Better information on its stability could improve storage. OBJECTIVE: To assess the stability of BTZ solution (1 mg/mL) in syringes and vials. METHODS: BTZ 1-mg/mL solutions were prepared by adding sterile NaCl 0.9% to Velcade vials containing 3.5 mg of lyophilized BTZ. Syringes were filled with 1 mL of solution and stored in the dark at 5 °C or 60 °C; others were not protected from light an
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Blinkova, Larisa, Danik M. Martirosyan, Yury Pakhomov, Olga Dmitrieva, Rachel Vaughan, and Michael Altshuler. "Nonculturable forms of bacteria in lyophilized probiotic preparations." Functional Foods in Health and Disease 4, no. 2 (2014): 66. http://dx.doi.org/10.31989/ffhd.v4i2.29.

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Анотація:
Background: Nonculturable cells are formed under stress. These viable but nonculturable (VBNC) cells retain the ability to revert to active growth and division when conditions become favorable, or after treatment with resuscitating factors. Information about the possible presence of VBNC in bacterial lyophilized probiotic preparations, foodstuffs, live vaccines, etc., indicates that human as well as animal intestines are a significant area for research.Methods: Samples were stored for different periods of time (up to 30 years) according to the manufacturers’ manuals. Total counts were conducte
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Cooper, G. R., S. J. Smith, D. A. Wiebe, M. Kuchmak, and W. H. Hannon. "International survey of apolipoproteins A1 and B measurements (1983-1984)." Clinical Chemistry 31, no. 2 (1985): 223–28. http://dx.doi.org/10.1093/clinchem/31.2.223.

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Анотація:
Abstract We report here results of a worldwide survey of apolipoprotein (apo) A1 and B measurements. A lyophilized pool of human serum was developed for the survey to test its suitability as a candidate Reference Material. Seventy-five laboratories from 18 countries responded to invitations to participate. Using several methods, they evaluated the mass concentration of apo A1 and B in the proposed Reference Material. The bias between laboratories and between analytical methods was then characterized. Fifty-five laboratories reported results before the deadline on measurement of at least one ap
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Abdul-Fattah, Ahmad M., Richard Oeschger, Holger Roehl, et al. "Investigating factors leading to fogging of glass vials in lyophilized drug products." European Journal of Pharmaceutics and Biopharmaceutics 85, no. 2 (2013): 314–26. http://dx.doi.org/10.1016/j.ejpb.2013.06.007.

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Yaswanth, Allamneni*1 T.E.G.K Murthy2 Mandava Venkata Basaveswara Rao3 Y. Udaya Bhaskara Rao4 M. Sivanath5. "VALIDATION OF RP-HPLC ANALYTICAL METHOD FOR ESTIMATION OF CARMUSTINE IN BULK AND LYOPHILIZED VIALS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 09 (2017): 416–23. https://doi.org/10.5281/zenodo.1036370.

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Анотація:
Carmustine is an anti-neoplastic agent. A reverse phase high-performance liquid chromatographic (RP-HPLC) assay method was developed by slightly modifying the USP method and validated for quantitative determination of carmustine in bulk drug and in lyophilized vials. The column utilized for the estimation of assay was 4.6 mm X 15-cm, 5-μm Packing L1 (C18) and the mobile phase employed was a mixture of acetonitrile and water in the ratio of 3:7. The detection was carried out at a wavelength of 200 nm with PDA detector. The flow rate is 1.5 mL per minute at a set temperature of 4-6°C with a tota
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Mazur, T. V., and О. V. Yablonska. "INFLUENCE OF TEMPERATURE AND ATMOSPHERIC FACTOR ON THE VIABILITY OF LYOPHILICALLY DRIED CULTURE HEMOLYTIC PASTEURELLA." Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology 22, no. 2 (2021): 242–46. http://dx.doi.org/10.36359/scivp.2021-22-2.28.

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Анотація:
The question of the stability of lyophilized culture, namely - the maximum preservation of its viability – is an extremely important indicator of microbiological work. Of particular interest is the study of the impact on the preservation of the viability of the lyophilized culture of the gas composition of the ampoule filler after the actual lyophilization. In this regard, an analysis was performed and the viability of hemolytic pasteurella cells was evaluated, the ampoules of which were filled with nitrogen, argon, respectively, or simply sealed in a vacuum atmosphere. The experiment used mat
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Частини книг з теми "Lyophilized Vials"

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Wang, Bingquan, Timothy R. McCoy, Michael J. Pikal, and Dushyant Varshney. "Lyophilization of Therapeutic Proteins in Vials: Process Scale-Up and Advances in Quality by Design." In Lyophilized Biologics and Vaccines. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2383-0_7.

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Searles, Jim, and Mathew Cherian. "Alternatives to Vial Lyophilization." In Lyophilized Biologics and Vaccines. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2383-0_11.

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Тези доповідей конференцій з теми "Lyophilized Vials"

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Chinnasami, Harish, Frank Breeden, Daniel Hayes, and Ram Devireddy. "Influence of Freezing (Thermal) Profiles on the Morphology and Mechanical Properties of Poly (L-Lactic Acid) Scaffolds." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80119.

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Анотація:
Bio-degradable Poly (l-lactic acid) (PLLA) scaffolds were prepared by using thermal liquid-liquid phase separation method. A solution of PLLA-Dioxane was prepared by dissolving PLLA in dehydrated 1,4-Dioxane. This PLLA-Dioxane solution was then directionally frozen in vials of similar dimensions but made of different materials (borosilicate glass, aluminum and copper). The frozen solution was then placed in a freeze-dryer to allow for the frozen dioxane to sublimate or lyophilized. The porosities of the resulting PLLA scaffolds were calculated and their porous structures were studied and compa
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