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Готові списки джерел за темами / Malignancy appear / Статті в журналах

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Статті в журналах з теми "Malignancy appear"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Masarova, Lucia, Gabriele Todisco, Taghi Manshouri, et al. "Therapy-related myelofibrosis does not appear to exist." Blood Advances 1, no. 14 (2017): 863–66. http://dx.doi.org/10.1182/bloodadvances.2017007369.

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2

Pinello, Katia, Irina Amorim, Isabel Pires, et al. "Vet-OncoNet: Malignancy Analysis of Neoplasms in Dogs and Cats." Veterinary Sciences 9, no. 10 (2022): 535. http://dx.doi.org/10.3390/vetsci9100535.

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Analysis of canine and feline tumor malignancy data can help clinicians identify high-risk patients and make more accurate decisions. Based on a sample of 16,272 cancer records, including 3266 cats and 13,006 dogs, collected from January 2019 to December 2021 in the Vet-OncoNet Network database, this study aimed to compare the tumor malignancy profile between cats and dogs, considering animal-related factors (sex, age, and breed), topography, and geographic location using a mixed-effects logistic regression model. Cats had a higher proportion of malignant tumors (78.7%) than dogs (46.2%), and

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3

Dando, Emily E., and Rina A. Anvekar. "Psoriasis Therapies and the Risk of Cutaneous Malignancy." SKIN The Journal of Cutaneous Medicine 1, no. 2 (2017): 55. http://dx.doi.org/10.25251/10.25251/skin.1.2.1.

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AbstractBackground: Systemic therapies for moderate to severe psoriasis target the dysregulated inflammatory response. However, their immunomodulatory properties may also contribute to carcinogenesis, leading to increased risk of cutaneous malignancy in patients exposed to systemic agents.Objective: A review of the literature was performed to evaluate the risk of cutaneous malignancy associated with the following therapies for moderate to severe psoriasis: PUVA, UVB, cyclosporine, methotrexate, retinoids, TNF-a inhibitors, IL-12/23 inhibitors, and IL-17 inhibitors.Results: Rates of NMSC, most

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4

Sun, Xiao Rong, Yonghong Zheng, Calum MacAulay, Stephen Lam, Alexei Doudkine, and Branko Palcic. "In VitroModel for Studying Malignancy Associated Changes." Analytical Cellular Pathology 25, no. 2 (2003): 95–102. http://dx.doi.org/10.1155/2003/238921.

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Malignancy associated changes (MAC) can be defined as subtle morphological and physiologic changes that are found in ostensibly normal cells of patients harboring malignant disease. It has been postulated that MAC have a potential to become a useful tool in detection, diagnosis and prognosis of malignant diseases. An in vitro cell culture model system was designed to study interactions between non‐small cell lung cancer (NSCLC) and the normal bronchial epithelium of the human respiratory tractin vivoto see if the MAC‐like phenomenon can be detected in such a system. In this study we examined c

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5

Salahuddin, Ayesha, and Muhammad Wasif Saif. "Pancreatic Tuberculosis or Autoimmune Pancreatitis." Case Reports in Medicine 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/410142.

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Introduction. Isolated pancreatic and peripancreatic tuberculosis is a challenging diagnosis due to its rarity and variable presentation. Pancreatic tuberculosis can mimic pancreatic carcinoma. Similarly, autoimmune pancreatitis can appear as a focal lesion resembling pancreatic malignancy. Endoscopic ultrasound-guided fine needle aspiration provides an effective tool for differentiating between benign and malignant pancreatic lesions. The immune processes involved in immunoglobulin G4 related systemic diseases and tuberculosis appear to have some similarities.Case Report. We report a case of

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6

Goldman, Steven A., and Samuel E. Gandy. "Squamous cell carcinoma as a late complication of intracerebroventricular epidermoid cyst." Journal of Neurosurgery 66, no. 4 (1987): 618–20. http://dx.doi.org/10.3171/jns.1987.66.4.0618.

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✓ Primary intracerebral squamous cell carcinoma is a rare sequela of benign cerebral epidermoid cysts. A case of presumed malignant transformation in a lateral ventricular epidermoid cyst is described, in which squamous cell carcinoma arose 33 years after the surgical resection of a benign epidermoid cyst. Three years after diagnosis of malignancy, the patient remains functional with a slowly invasive tumor. This case provides a rare description of the natural history of forebrain squamous cell carcinoma, which would appear to be a more indolent tumor than previously realized.

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7

Khozeimeh, Nini, and Cynthia Gingalewski. "Thyroid Nodules in Children: A Single Institution's Experience." Journal of Oncology 2011 (2011): 1–4. http://dx.doi.org/10.1155/2011/974125.

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Thyroid nodules in children are uncommon but often present an increased risk of malignancy in comparison to their adult counterpart. Multiple diagnostic modalities are frequently employed to characterize these nodules including ultrasound, radionuclide scans, fine needle aspiration (FNA), thyroid function tests, and evaluation of patient demographics. We chose to evaluate if any of these modalities influence treatment or signify a tendency for a nodule to represent a malignant lesion. A retrospective review of patients <21 years of age who underwent partial or total thyroidectomy from 2004

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8

Jamal, Chowdhury Yakub, and Ismet Nigar. "Invasive Fungal Infections in Children with Hematological Malignancy." Bangladesh Journal of Child Health 45, no. 1 (2021): 34–40. http://dx.doi.org/10.3329/bjch.v45i1.55472.

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Invasive fungal infections (IFI) are a major cause of morbidity and mortality in patients with haematolgical malignancies. Factors that appear to be associated with IFIs in both children and adults in this severely immunosuppressed population are the underlying malignancies, presence of profound and long lasting neutropenia, high intensity of the therapeutic regimens, hematopoietic stem cell transplantation and previous antibiotic therapy. In patients with hematological malignancy most invasive fungal infections are caused by Candida and Aspergillous species. Though the incidence of IFI in adu

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9

Sardiñas, Carlos, Bagher Nouri, Andrea Cifuentes, and María Eugenia Oropeza. "Primary Adenocarcinoma at Colostomy Site: Report of a Clinical Case." Journal of Coloproctology 42, no. 01 (2021): 102–6. http://dx.doi.org/10.1055/s-0041-1736647.

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AbstractColorectal cancer (CRC) is the fourth most frequently diagnosed cancer in the United States and it is found in 17% of patients thought to have complicated diverticular disease. However, primary adenocarcinoma rarely occur in the colostomy site and the risk of developing malignancy is similar to that of any other colonic segment. Polyps found in CRC screenings can be divided into the following types: hyperplastic polyps, polyps with no malignant potential, adenomatous polyps, polyps with malignant potential, and malignancies. Local complications of the colostomy can appear in the immedi

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10

Tamura, Ryo, Taichi Hirotani, Yoshitomo Yasui, and Hideaki Okajima. "Rapidly growing intramuscular lipoma: a unique entity of benign lipomas in children." BMJ Case Reports 17, no. 2 (2024): e253408. http://dx.doi.org/10.1136/bcr-2022-253408.

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This report presents a case of an intramuscular lipoma observed in the left back of a healthy female toddler. It was resected after 3 months of observation because of rapid enlargement, raising suspicion of malignancy. Histopathological examination confirmed a diagnosis of intramuscular lipoma without malignant and blastemal components. Intramuscular lipomas are benign neoplasms that mostly appear as a rapidly growing tumour. Several hypotheses regarding the pathogenesis of this characteristic growth pattern have been proposed, including atrophy of the surrounding muscle, reactive adipocytic n

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11

KALAMPOKAS, EMMANOUIL, NIKOLAOS VLAHOS, THEODOROS KALAMPOKAS, and MAHALAKSHMI GURUMURTHY. "Common Malignancies During Pregnancy: A Comprehensive Review." Cancer Diagnosis & Prognosis 1, no. 3 (2021): 103–9. http://dx.doi.org/10.21873/cdp.10015.

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Malignant disease complicates pregnancy in up to 1 per 1,000-2,000 cases. Pregnancy itself does not constitute a predisposing factor for malignancy. Management and treatment of patients suffering from a malignancy during pregnancy still represents a challenge in everyday clinical practice. Recent advances in imaging, diagnostic and overall treatment modalities have tailored the management of patients, specifically those who wish to maintain the pregnancy. The aim of this review was to provide clinicians with concise information on the management of the most common malignancies during pregnancy

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12

Politi, Y., J. Ophir, and S. Brenner. "Cutaneous paraneoplastic syndromes." Acta Dermato-Venereologica 73, no. 3 (1993): 161–70. http://dx.doi.org/10.2340/0001555573161170.

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A review of a variety of cutaneous paraneoplastic conditions is presented. Although the conditions discussed appear in only 7/15% of cancer patients, they are considered indicators of possible underlying malignancy.

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13

Femilian, Afryla, Afina Hasnasari Heningtyas, and Dwi Suhartiningtyas. "The Training and Empowerment of Health Cadres in Early Detection of Oral Cancer with SAMURI in Margodadi Seyegan." Proceeding International Conference of Community Service 1, no. 1 (2023): 277–81. http://dx.doi.org/10.18196/iccs.v1i1.33.

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Premalignant lesions are morphologically altered tissues, more likely to develop cancer. Premalignant lesions are more commonly expressed as a general condition associated with a significant risk of cancer. These lesions can appear in the oral cavity. Oral lichen planus, submucosal oral fibrosis, and leukoplakia are premalignant mucosal lesions that have the potential to become malignant in the oral cavity in the development of oral squamous cell carcinoma. Public health cadres are men or women selected by the community and trained to deal with individual and community health problems to work

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14

Yadav, Ajay Kumar, Milan Shrestha, Sabin Rajbhandari, et al. "Extraosseous Ewing Sarcoma With Upper Gastrointestinal Bleeding." ACG Case Reports Journal 11, no. 8 (2024): e01447. http://dx.doi.org/10.14309/crj.0000000000001447.

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ABSTRACT Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) is a type of malignancy that usually appears as a tumor in the bone. However, in a few patients with ES/PNET, it can occur outside of the bone. Although extraosseous ES/PNET can appear in various parts of the body, involvement of small bowel is rare. If it does, it can present with vague abdominal pain and gastrointestinal bleeding. This case report presents a 28-year-old gentleman with extraosseous ES/PNET in the duodenum who experienced gastrointestinal bleeding as a presenting symptom.

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15

Davis, Jeremiah C., Christopher G. Dove, and Helen C. Su. "Genetic, Clinical, and Laboratory Markers for DOCK8 Immunodeficiency Syndrome." Disease Markers 29, no. 3-4 (2010): 131–39. http://dx.doi.org/10.1155/2010/972591.

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DOCK8 immunodeficiency syndrome (DIDS) is a combined immunodeficiency characterized by recurrent viral infections, severe atopy, and early onset malignancy. Genetic studies revealed large, unique deletions in patients from different families and ethnic backgrounds. Clinical markers of DIDS include atopic dermatitis, allergies, cutaneous viral infections, recurrent respiratory tract infections, and malignancy. Immune assessments showed T cell lymphopenia, hyper-IgE, hypo-IgM, and eosinophilia. The impaired lymphocyte functions in DIDS patients appear central for disease pathogenesis.

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16

Artac, Mehmet, Hakan Bozcuk, Mustafa Ozdogan, et al. "Different Clinical Features of Primary and Secondary Tumors in Patients with Multiple Malignancies." Tumori Journal 91, no. 4 (2005): 317–20. http://dx.doi.org/10.1177/030089160509100406.

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Clinical features of the first and second primaries in patients with multiple malignancies have not been extensively studied. We compared patient and treatment characteristics of the primary malignancy in 48 consequent multiple primary cancer patients with those of the second primary in the same cohort. The second primaries comprised fewer breast cancers; 29.2% of primaries as opposed to 10.4% of second tumors were breast cancer (P = 0.049). In addition, primary tumors tended to be at a lower TNM stage than secondary tumors (P = 0.060). The median overall survival after the diagnosis of the fi

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17

Widyaswari, Meidyta Sinantryana, Hans Lumintang, and Troef Soemarno. "IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA." Medical and Health Science Journal 3, no. 1 (2019): 47–54. http://dx.doi.org/10.33086/mhsj.v3i1.926.

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   Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes c

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18

Ramji, Ashwath Narayan. "Cutaneous horn in a sun-protected site harbouring unusual malignancy." International Surgery Journal 6, no. 4 (2019): 1415. http://dx.doi.org/10.18203/2349-2902.isj20191291.

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Cutaneous horns are conical, circumscribed projections formed by desquamation and layering of keratin. Although they can appear on the skin anywhere on the body, they are most commonly seen on the sun-exposed surfaces, and are often associated with solar keratosis. Cutaneous horns are most often benign, however they are a potential site of malignancy and may harbor premalignant or malignant lesions, the most common being squamous cell carcinoma, the causal relationship being straightforward and both squamous cell carcinoma and cutaneous horns can be equated with the common epithelial maker ker

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19

Cavrois, M., S. Wain-Hobson, A. Gessain, Y. Plumelle, and E. Wattel. "Adult T-cell leukemia/lymphoma on a background of clonally expanding human T-cell leukemia virus type-1-positive cells." Blood 88, no. 12 (1996): 4646–50. http://dx.doi.org/10.1182/blood.v88.12.4646.bloodjournal88124646.

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Tumorous and nontumorous samples from patients with various forms of adult T-cell leukemia/lymphoma (ATLL) were analyzed using the sensitive inverse polymerase chain reaction (PCR) technique. In all samples, oligoclonal expansion of human T-cell leukemia virus (HTLV)-1 bearing T cells were detected, even for the tumorous samples that were mainly monoclonal by Southern blotting. For one case of smouldering ATLL, chemotherapy apparently reduced the number of detectable clones. Taken together with similar data on asymptomatic and symptomatic HTLV-1 carriers without malignancy, it would appear tha

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20

Muhammad Rosyidi, Rohadi, Hamsu Kadriyan, Ahmad Taufik, Decky Aditya Zulkarnaen, and Lalu Muhammad Kamal Abdurrosid. "Karsinoma Nasofaring, Review." JURNAL SAINS TEKNOLOGI & LINGKUNGAN 10, no. 4 (2024): 662–70. https://doi.org/10.29303/jstl.v10i4.787.

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Nasopharyngeal carcinoma is a malignancy that arises due to abnormal growth of body cells that appear in the nasopharyngeal area, namely the area above the throat and behind the nose. Almost 60% of malignant tumors of the head and neck are nasopharyngeal carcinomas, followed by malignant tumors of the nose and paranasal sinuses (18%), larynx (16%), and oral cavity tumors. Nasopharyngeal carcinoma is endemic in certain regions of the world, especially in Southeast Asia, and has a poor prognosis, with the highest incidence in southern China. Indonesia is one of the countries with a high prevalen

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21

Bohler, Iain, Phillip Fletcher, Amanda Ragg, and Andrew Vane. "A Ruptured Digital Epidermal Inclusion Cyst: A Sinister Presentation." Case Reports in Orthopedics 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/9035246.

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Epidermal inclusion cysts are benign cutaneous lesions caused by dermal or subdermal implantation and proliferation of epidermal squamous epithelium as a result of trauma or surgery. They are typically located on the scalp, face, trunk, neck, or back; however they can be found anywhere on the body. Lesions are asymptomatic unless complicated by rupture, malignant transformation to squamous cell carcinoma, or infection at which point they can clinically appear as more sinister pathologies. We present the case of a 45-year-old laborer with a ruptured epidermal inclusion cyst, manifesting clinica

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22

Dahmani, Youness, Monsef Boufettal, Reda Allah Bassir, et al. "Post-traumatic Pain: Think of Circumscribed Myositis Ossificans." SAS Journal of Surgery 7, no. 6 (2021): 326–29. http://dx.doi.org/10.36347/sasjs.2021.v07i06.016.

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Myositis ossificans is a benign condition, essential to know because the presence of ossifications of the soft tissues adjacent to the bone, always makes one fear a neoplastic localization in a young patient. We report in this study a rare case of traumatic circumscribed myositis ossificans of the thigh. Imaging plays an important role in the positive diagnosis, the differential diagnosis and the follow-up of the characteristic three-phase evolution of MOC. However, this pseudotumor may appear clinically and radiologically as a malignant tumor, a thorough knowledge of clinical and morphologica

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23

Nagare, A.G* Avhad V.R Hawaldar R.H Jathar N.B Narwade S.N Prof. Randhawan B.B. "Systematization Of Environmental Risk Factors For Malignancy." International Journal of Pharmaceutical Sciences 2, no. 7 (2024): 1440–45. https://doi.org/10.5281/zenodo.12782132.

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The cancer process begins with altered cell function caused by genetic and epigenetic alterations. These changes appear as chromosomal or molecular defects, causing genetic instability. It is difficult to pinpoint particular causes, but it is apparent that a combination of risk factors plays a substantial role in cancer development. Cancer onset is influenced by environmental, internal, and hereditary factors. The majority of research on malignant tumor formation has focused on identifying environmental and genetic factors that influence cancer rates. According to current research, outside env

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24

Manini, Claudia, Estíbaliz López-Fernández, Nicola Cruciano, Alessandro Comandone, and José I. López. "Benign Mesothelial Proliferations of the Tunica Vaginalis Testis." Clinics and Practice 13, no. 5 (2023): 1130–36. http://dx.doi.org/10.3390/clinpract13050101.

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The correct diagnosis of mesothelial proliferations is a classic problem for pathologists, and one which has important clinical implications. A significant number of such cases appear associated with recurrent hydrocele, as an irritative/reactive response to this condition. The morphological spectrum of mesothelial lesions in this topography is broad, and a set of benign conditions may appear, sometimes with florid gross features and cytologic pseudo-atypia. Here, we present two different examples in which malignancy was initially considered in the differential diagnosis.

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25

Poller, David N., Hakim Megadmi, Matthew J. A. Ward, and Pierpaolo Trimboli. "Hürthle Cells on Fine-Needle Aspiration Cytology Are Important for Risk Assessment of Focally PET/CT FDG Avid Thyroid Nodules." Cancers 12, no. 12 (2020): 3544. http://dx.doi.org/10.3390/cancers12123544.

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This study assesses the role of [18F] FDG PET/CT, fine needle aspiration (FNA) cytology and ultrasound in the 1–2% of patients with focally positive thyroid nodules on FDG PET/CT. All FDG PET/CT scans with focally increased thyroid FDG PET/CT uptake performed over 37 months in one institution were matched to patients undergoing thyroid FNA. Diffuse FDG PET/CT uptake patients were excluded. A total of 47 patients showed focally increased thyroid uptake. Consistent with previous studies, 18 (38.2%) patients had malignancy—12 primary thyroid carcinoma, 1 parathyroid carcinoma, 3 metastatic carcin

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26

Nagare, A. G.*1 Avhad V. R.2 Randhawan B. B.6. "Systematization Of Environmental Risk Factors For Malignancy." International Journal of Pharmaceutical Sciences 2, no. 7 (2024): 1587–92. https://doi.org/10.5281/zenodo.12792850.

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The cancer process begins with altered cell function caused by genetic and epigenetic alterations. These changes appear as chromosomal or molecular defects, causing genetic instability. It is difficult to pinpoint particular causes, but it is apparent that a combination of risk factors plays a substantial role in cancer development. Cancer onset is influenced by environmental, internal, and hereditary factors. The majority of research on malignant tumor formation has focused on identifying environmental and genetic factors that influence cancer rates. According to

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27

Wang, Jiaan-Der, Ya-Yu Wang, Shih-Yi Lin, et al. "Exosomal HMGB1 Promoted Cancer Malignancy." Cancers 13, no. 4 (2021): 877. http://dx.doi.org/10.3390/cancers13040877.

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Reciprocal crosstalk between platelets and malignancies underscores the potential of antiplatelet therapy in cancer treatment. In this study, we found that human chronic myeloid leukemia K562 cell-differentiated megakaryocytes and murine platelets produced bioactive substances and these are released into the extracellular space, partly in their exosomal form. High-mobility group box 1 (HMGB1) is a type of exosomal cargo, and the antiplatelet drugs aspirin and dipyridamole interfered with its incorporation into the exosomes. Those released substances and exosomes, along with exogenous HMGB1, pr

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28

Hunter, Brian C., Alfio Ferlito, Kenneth O. Devaney, and Alessandra Rinaldo. "Alveolar Soft Part Sarcoma of the Head and Neck Region." Annals of Otology, Rhinology & Laryngology 107, no. 9 (1998): 810–14. http://dx.doi.org/10.1177/000348949810700914.

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Alveolar soft part sarcoma is a soft tissue malignancy most often found in the extremities of young adults; when these tumors arise in the head and neck area, they usually appear in the orbit or the tongue. Their initial behavior is relatively indolent, but over time a sizable number of these tumors recur locally and metastasize; as such, they are best regarded as fully malignant neoplasms. The derivation of these tumors remains uncertain: while some have suggested that these are tumors of muscle origin and others have postulated a neuroendocrine origin, the evidence accumulated to date is con

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Romanova, Nina. "Assessment Challenges of Echogenic Breast Lesions." Canadian Journal of Medical Sonography 13, no. 3 (2022): 17–21. http://dx.doi.org/10.3138/cjms.v13i3.44.

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An echogenic breast mass is defined as a hyperechoic lesion compared with subcutaneous adipose tissue at ultrasonography (US). This is in accordance with the US lexicon of the Breast Imaging Reporting and Data System (BI-RADS) of the American College of Radiology. Although most echogenic solid breast masses identified on ultrasound imaging are benign, hyper-echogenicity alone does not exclude malignancy. Approximately 0.5% of malignant breast lesions appear echogenic. Therefore, upon finding a solid, echogenic mass on ultrasound, it is important to correlate with the mammographic findings to d

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30

Zineb, Tazi, Boumaaza Sara, Jayi Sofia, Fdili Alaoui Fatimzehra, Chaara Hikmat, and Melhouf Moulay Abdelilah. "Ovarian masses and pregnancy: About 2 cases and literature review (experience of Gyneco-obstetrics service 2 Fez)." Obstetrics & Gynecology International Journal 15, no. 1 (2024): 25–27. http://dx.doi.org/10.15406/ogij.2024.15.00729.

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Management of adnexal masses during pregnancy can be challenging for the patient and clinician. The specter of a possible malignant tumor may influence the decision to intervene rather than the expected management. The etiologies of ovarian masses vary depending on the age of the parturient, and therefore, benign entities such as functional ovarian cysts, benign cystic teratomas, and serous cystadenomas predominate. In cases of malignancy, these are generally germ cell tumors and borderline, low-grade ovarian tumors. Ultrasound is the primary modality used to detect ovarian masses and assess t

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31

Dobromylskyj, Melanie J., Fernando Martinez, and Anna Lovell. "Spindle cell sarcomas, suggestive of peripheral nerve sheath tumours, arising in the tongues of two cats." Journal of Feline Medicine and Surgery Open Reports 5, no. 2 (2019): 205511691987525. http://dx.doi.org/10.1177/2055116919875259.

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Case summary Two domestic shorthair cats, one an 11-year-old female neutered cat and the other a 13-year-old male neutered cat, presented with partly raised, well-demarcated masses at the rostral tip of the tongue. Histological examination and immunohistochemical staining were consistent with sarcomas, and were most suggestive of peripheral nerve sheath tumours. One tumour had histological features consistent with a malignant peripheral nerve sheath tumour (PNST). Relevance and novel information Feline PNSTs arising on the tongue are rarely described in the published literature, and, to our kn

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32

Vijenthira, Abi, Inna Y. Gong, Thomas A. Fox, et al. "Outcomes of patients with hematologic malignancies and COVID-19: a systematic review and meta-analysis of 3377 patients." Blood 136, no. 25 (2020): 2881–92. http://dx.doi.org/10.1182/blood.2020008824.

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Abstract Outcomes for patients with hematologic malignancy infected with COVID-19 have not been aggregated. The objective of this study was to perform a systematic review and meta-analysis to estimate the risk of death and other important outcomes for these patients. We searched PubMed and EMBASE up to 20 August 2020 to identify reports of patients with hematologic malignancy and COVID-19. The primary outcome was a pooled mortality estimate, considering all patients and only hospitalized patients. Secondary outcomes included risk of intensive care unit admission and ventilation in hospitalized

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Almasri, Muna, Khalifa Bshesh, Wafa Khan, et al. "Cancer Patients and the COVID-19 Vaccines: Considerations and Challenges." Cancers 14, no. 22 (2022): 5630. http://dx.doi.org/10.3390/cancers14225630.

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Few guidelines exist for COVID-19 vaccination amongst cancer patients, fostering uncertainty regarding the immunogenicity, safety, and effects of cancer therapies on vaccination, which this review aims to address. A literature review was conducted to include the latest articles covering the immunogenicity and safety of COVID-19 vaccination in patients with solid and hematologic cancers receiving various treatments. Lower seropositivity following vaccination was associated with malignancy (compared to the general population), and hematologic malignancy (compared to solid cancers). Patients rece

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Equebal, Ameed, Neyaz Osama, Ghosal Vasundhara, Jhalani Rakesh, Ballav Ambar, and Keshkar Sanjay. "Myositis Ossificans Circumscripta: A Case Report." Indian Journal of Physical Medicine and Rehabilitation 24, no. 3 (2013): 70–72. http://dx.doi.org/10.5005/ijopmr-24-3-70.

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Abstract Introduction Myositis ossificans circumscripta (MOC) is a form of heterotopic ossification (HO) that is benign in nature but may appear clinically and radiologically as a malignant neoplasm. A 26 years old male patient of traumatic spastic paraplegia, secondary to compression fracture of D8-D10 vertebra presented with severe LBP, more around right buttock with hip movement. During investigations, the presence of large heterotopic ossification mass was noted on rightside of pelvis. Diagnosis was confirmed by blood investigations, x-rays, MRI. Malignancy was excluded by bone biopsy. Cas

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Zivanovic, Dubravka, Srdjan Tanasilovic, Dusan Skiljevic, et al. "Atypical pyoderma gangrenosum in a patient with osteomyelofibrosis." Vojnosanitetski pregled 64, no. 11 (2007): 787–89. http://dx.doi.org/10.2298/vsp0711787z.

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Background. Atypical forms of pyoderma gangrenosum generally appear on the upper extremities; most frequently they are associated with myeloproliferative disorders, including osteomyelofibrosis. A response to systemic steroids is more pronounced than in classical form. Sometimes it may be the first sign of an underlying malignancy. Case report. We reported a patient with atypical pyoderma gangrenosum developed during the course of a myeloid malignancy - osteomyelofibrosis. The lesions occurred after a minor trauma. Painful blistering plaques, with an elevated, bluish-gray border were located o

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Rigdon, Edward E. "Trousseau's Syndrome and Acute Arterial Thrombosis." Cardiovascular Surgery 8, no. 3 (2000): 214–18. http://dx.doi.org/10.1177/096721090000800308.

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This report describes three patients treated for acute arterial thrombosis due to malignancy-related hypercoagulability (Trousseau's syndrome). The average age was 59 yr. There were two women and one man. The cancers were breast, lung, and pancreas. Atherosclerosis or nonneoplastic hypercoagulable states did not appear to be a factor in any patient. One patient who presented with irreversible arm ischemia and Stage IV breast cancer underwent primary amputation. The other two patients underwent immediate surgical thrombectomy and thrombolytic therapy, and malignancy was discovered during postop

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Maksymiuk, Andrew W., Paramjit S. Tappia, Bram Ramjiawan, et al. "Follow-up evaluation of outliers with elevated spermine-spermidine acetyltransferase-1 activity." Journal of Clinical Oncology 37, no. 15_suppl (2019): e14536-e14536. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e14536.

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e14536 Background: In the evolving role of biomarkers, proteinomic signatures related to up-regulation of polyamine synthesis including spermine/spermidine acetyltransferase-1 (SSAT-1) appear to be promising markers of malignancy. Acetylamantadine (AA) excretion, a measure of SSAT-1 up-regulation, has been shown to be a marker for malignant proliferation. In preliminary analyses of ostensibly normal individuals from Canada (Winnipeg) and Bangladesh (Dhaka), a proportion were identified to have evidence of SSAT-1 up-regulation above the expected non-malignant range (outliers). These outliers we

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Hennessey, Derek Barry, Adrian B. Brady, Rhona Dempsey, and Kenneth Patterson. "Renal lobar dysmorphism: a potential mimic of renal malignancy." BMJ Case Reports 14, no. 2 (2021): e237096. http://dx.doi.org/10.1136/bcr-2020-237096.

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A renal pseudotumour is any apparent renal mass that simulates a tumour on radiological imaging but is composed of normal tissue. Renal pseudotumours may be inflammatory, vascular, postsurgical or congenital. We report a case of renal lobar dysmorphism (RLD) of the kidney, a congenital renal pseudotumour. A 45-year-old man presented with scrotal swelling. Testicular ultrasound showed an epididymal cyst. Renal ultrasound showed a right solid renal apparent mass of 2.4 cm in diameter. Triphasic renal CT showed this was consistent with RLD. Intravenous urography confirmed a central calyx within t

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Kumar, Sanyal, Bhawna Satija, Mahesh K. Mittal, and Brij B. Thukral. "Unusual Mediastinal Dumbbell Tumor Mimicking an Aggressive Malignancy." Journal of Clinical Imaging Science 2 (October 31, 2012): 67. http://dx.doi.org/10.4103/2156-7514.103057.

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Hydatid cyst is known to affect all possible anatomical locations of the human body. However, the mediastinal localization is extremely rare. This benign, commonly asymptomatic and incidentally detected disease, at times may simulate an aggressive malignancy by its potential to cause osseous destruction and intraspinal extension. A young female, farmer by occupation, presented with complaints of left chest pain and monoparesis of the left lower limb. Radiograph followed by computed tomography (CT) of the chest demonstrated a cystic mass within the posterior mediastinum, eroding and scalloping

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Tsoli, Marina, Kosmas Daskalakis, Eva Kassi, Gregory Kaltsas, and Apostolos V. Tsolakis. "A Critical Appraisal of Contemporary and Novel Biomarkers in Pheochromocytomas and Adrenocortical Tumors." Biology 10, no. 7 (2021): 580. http://dx.doi.org/10.3390/biology10070580.

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Pheochromocytomas/Paragangliomas (PPGLs) and adrenocortical tumors are rare neoplasms with significant heterogeneity in their biologic and clinical behavior. Current diagnostic and predictive biomarkers include hormone secretion, as well as histopathological and genetic features. PPGL diagnosis is based on biochemical measurement of catecholamines/metanephrines, while histopathological scoring systems have been proposed to predict the risk of malignancy. Adrenocortical tumors are mostly benign, but some can be malignant. Currently, the stage of disease at diagnosis and tumor grade, appear to b

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Ng, Andrea K., M. V. Patricia Bernardo, Edie Weller, et al. "Second malignancy after Hodgkin disease treated with radiation therapy with or without chemotherapy: long-term risks and risk factors." Blood 100, no. 6 (2002): 1989–96. http://dx.doi.org/10.1182/blood-2002-02-0634.

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Abstract The excess risk of second malignancy after Hodgkin disease is an increasing problem. In light of the long-term data, guidelines for follow-up of survivors of Hodgkin disease need to be redefined. In this study we attempt to analyze the long-term risks and temporal trends, identify patient- and treatment-related risk factors, and determine the prognosis of patients who develop a second malignancy after radiation treatment with or without chemotherapy for Hodgkin disease. Among 1319 patients with clinical stage I-IV Hodgkin disease, 181 second malignancies and 18 third malignancies were

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KEYSTONE, EDWARD C. "Does Anti-Tumor Necrosis Factor-α Therapy Affect Risk of Serious Infection and Cancer in Patients with Rheumatoid Arthritis?: A Review of Longterm Data". Journal of Rheumatology 38, № 8 (2011): 1552–62. http://dx.doi.org/10.3899/jrheum.100995.

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Given the important role tumor necrosis factor-α (TNF-α) antagonists play in managing rheumatoid arthritis and the concern for safety during longterm therapy, we reviewed the latest evidence regarding longterm risk of infection and malignancy with TNF-α antagonists. Our objective was to provide clinicians with information that can be used to counsel and monitor patients who may be candidates for biologic therapy for rheumatoid arthritis (RA). Risk is examined in the context of background infection and malignancy rates in RA. Randomized controlled trial (RCT) data and observational studies summ

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Lochan, R., A. K. Daly, H. L. Reeves, and R. M. Charnley. "Family History of Cancer and Tobacco Exposure in Index Cases of Pancreatic Ductal Adenocarcinoma." Journal of Oncology 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/215985.

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Aim. To examine interaction between history of cancer in first-degree relatives and tobacco smoking in index patients of pancreatic adenocarcinoma.Methods. We carried out a case-control involving 113 patients with pancreatic adenocarcinoma and 110 controls over a 12-month period at the Freeman Hospital, Newcastle upon Tyne, UK. They were all administered a detailed tobacco exposure questionnaire and a family history questionnaire. We calculated cumulative tobacco exposure and risk for pancreas cancer.Results. Both smokers (OR 3.01 (95% CI: 1.73 to 5.24)) and those with a family history of mali

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Minhas, G. S., A. Bukhari, Y. Yuan, et al. "A43 TOPICAL HEMOSTATIC AGENTS: A POTENTIAL BREAKTHROUGH IN MALIGNANCY-RELATED GI BLEEDING? A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS." Journal of the Canadian Association of Gastroenterology 8, Supplement_1 (2025): i17. https://doi.org/10.1093/jcag/gwae059.043.

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Abstract Background Malignancy-related gastrointestinal bleeding (GIB) has been challenging to treat with conventional endoscopic techniques. Topical hemostatic agents (THAs), which do not cause mucosal injury and can be applied over large surface areas, may offer a promising solution in cancer-related GIB. Aims To assess the effectiveness and safety of THAs in malignancy-related GIB compared to conventional endoscopic techniques. Methods We conducted a systematic review using MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials until March 2024. RCTs that compared THA vs conven

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Chowdhury, Afrin Sultana, and Saheda Tamanna. "Radiation-induced side effects in breast cancer patients and factors affecting them." Asian Journal of Medical and Biological Research 6, no. 2 (2020): 138–48. http://dx.doi.org/10.3329/ajmbr.v6i2.48044.

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Breast cancer is the most frequent malignancy and the leading cause of cancer morbidity and mortality in women worldwide. Radiation therapy (RT) is a widely used approach for its treatment. About 50% of patients with malignant breast tumors receive radiation therapy and most of them appear to tolerate it, but some experience severe side effects induced by this therapy. This variability of response may be caused by several factors, like age, inflammatory responses, body weight and variation in genes involved in the response to radiation-induced DNA damage. To limit radiotherapy side effects in

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Ino, Yasushi, Jonathan S. Silver, Lisa Blazejewski, et al. "Common Regions of Deletion on Chromosome 22q12.3-q13.1 and 22q13.2 In Human Astrocytomas Appear Related To Malignancy Grade." Journal of Neuropathology and Experimental Neurology 58, no. 8 (1999): 881–85. http://dx.doi.org/10.1097/00005072-199908000-00010.

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Nikolic, Branka, Aleksandar Ljubic, Milan Terzic, Aleksandra Arandjelovic, Srdjan Babic, and Milos Vucic. "Developing retroperitoneal anaplastic carcinoma with choriocarcinoma focus after ovarian non-gestastional choriocarcinoma: Case report." Vojnosanitetski pregled 69, no. 12 (2012): 1097–100. http://dx.doi.org/10.2298/vsp101231031n.

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Introduction. Choriocarcinoma is a malignant form of gestational trophoblastic neoplasm (GTN). It is a rare event but also a curable malignancy. In the majority of instancies it developes after any gestational event. In some cases it developes as non-gestational extrauterine malignancy. Prognosis of choriocarcinoma is poor when invasion and metastases appear early and spread fast. This form of choriocarcinoma can lead to incurable and letal outcome. Case report. We presented a 20-year-old patient with abdominal and retroperitoneal malignancy - anaplastic carcinoma combined with choriocarcinoma

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Huynh, Melissa Jessica, Andrew Gusev, Francesco Palmas, et al. "Using high-resolution magic angle spinning magnetic resonance spectroscopy to characterize the metabolomic profile of renal cell carcinoma." Journal of Clinical Oncology 38, no. 6_suppl (2020): 710. http://dx.doi.org/10.1200/jco.2020.38.6_suppl.710.

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710 Background: Renal cell carcinoma (RCC) is a metabolic disease, with the various subtypes exhibiting aberrations in different metabolic pathways. Metabolomics may offer greater sensitivity for revealing disease biology than evaluation of tissue morphology. In this study, we investigate the metabolomic profile of RCC using high resolution magic angle spinning (HRMAS) magnetic resonance spectroscopy (MRS). Methods: Tissue samples were obtained from radical or partial nephrectomy specimens that were fresh frozen & stored at -80ºC. Tissue HRMAS MRS was performed by a Bruker AVANCE spectrome

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Keyhan, Sanaz, Claude Hughes, Thomas Price, and Suheil Muasher. "An Update on Surgical versus Expectant Management of Ovarian Endometriomas in Infertile Women." BioMed Research International 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/204792.

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Ovarian endometriomas are a common manifestation of endometriosis that can represent a more severe stage of the disease. There is much debate over the treatment of these cysts in infertile women, particularly before use of assisted reproductive technologies. Evidence exists that supports surgical excision of ovarian endometriomas, as well as evidence that cautions against surgical intervention. Certain factors need to be examined closely before proceeding with surgery or continuing with expectant management. These include the patient’s symptoms, age, ovarian reserve, size and laterality of the

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Murray, Paul G., and Lawrence S. Young. "Epstein–Barr virus infection: basis of malignancy and potential for therapy." Expert Reviews in Molecular Medicine 3, no. 28 (2001): 1–20. http://dx.doi.org/10.1017/s1462399401003842.

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The Epstein–Barr virus (EBV) is a human herpesvirus that is usually carried lifelong as an asymptomatic infection. EBV is the causative agent of infectious mononucleosis and has been linked to the development of several malignant tumours, including B-cell neoplasms such as Burkitt's lymphoma and Hodgkin's disease, certain forms of T-cell lymphoma, and some epithelial tumours, such as undifferentiated nasopharyngeal carcinoma and a proportion of gastric cancers. All these tumours are characterised by the presence of multiple extrachromosomal copies of the circular viral genome in the tumour cel

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