Готові списки джерел за темами / Matrice MALDI

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Добірка наукової літератури з теми "Matrice MALDI"

Автор: Grafiati

Опубліковано: 22 грудня 2023

Оновлено: 31 липня 2025

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Статті в журналах з теми "Matrice MALDI"

Rubakhin, Stanislav S., and Jonathan V. Sweedler. "Transparent triethylamine-containing MALDI matrices." Israel Journal of Chemistry 47, no. 2 (2007): 185–93. http://dx.doi.org/10.1560/ijc.47.2.185.

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Meier, Michael A. R., Nico Adams, and Ulrich S. Schubert. "Statistical Approach To Understand MALDI-TOFMS Matrices: Discovery and Evaluation of New MALDI Matrices." Analytical Chemistry 79, no. 3 (2007): 863–69. http://dx.doi.org/10.1021/ac061173v.

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HAZAMA, Hisanao, and Kunio AWAZU. "Matrices for MALDI Using an Infrared Laser." Journal of the Mass Spectrometry Society of Japan 64, no. 5 (2016): 183–86. http://dx.doi.org/10.5702/massspec.s16-38.

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Fresnais, Margaux, Esra Yildirim, Seda Karabulut, et al. "Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives." Molecules 26, no. 5 (2021): 1281. http://dx.doi.org/10.3390/molecules26051281.

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Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has rarely been used in the field of therapeutic drug monitoring, partly because of the complexity of the ionization processes between the compounds to be quantified and the many MALDI matrices available. The development of a viable MALDI-MS method that meets regulatory guidelines for bioanalytical method validation requires prior knowledge of the suitability of (i) the MALDI matrix with the analyte class and properties for ionization, (ii) the crystallization properties of the MALDI matrix with automation features, and (

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FUKUYAMA, Yuko. "MALDI MS Analysis Using Liquid Matrices." Journal of the Mass Spectrometry Society of Japan 64, no. 5 (2016): 175–78. http://dx.doi.org/10.5702/massspec.s16-36.

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Lin, Chih-Hao, Chuping Lee, Yu-Cheng Wu, and I.-Chung Lu. "New Strategy to Preserve Phosphate by Ionic Liquid Matrices in Matrix-Assisted Laser Desorption/Ionization: A Case of Adenosine Nucleotides." Molecules 25, no. 5 (2020): 1217. http://dx.doi.org/10.3390/molecules25051217.

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Adenosine -5′-triphosphate (ATP) plays a valuable role in metabolic activity to produce adequate energy in a biosystem. A high ATP/AMP ratio has a correlation with diabetes that induces suppression of AMP-activated protein kinase (AMPK). Matrix-assisted laser desorption/ionization (MALDI)–mass spectrometry (MS) has outstanding potential in determining the ratio of several types of adenosine phosphates in a sample to rapidly understand the primary energy transfer in metabolism. Although MALDI is viewed as a soft ionization technique for MS analysis, excess photon energy might crack the phosphat

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Kim, Seung-Woo, Sunbum Kwon, and Young-Kwan Kim. "Graphene Oxide Derivatives and Their Nanohybrid Structures for Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Analysis of Small Molecules." Nanomaterials 11, no. 2 (2021): 288. http://dx.doi.org/10.3390/nano11020288.

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Matrix-assisted laser desorption/ionization (MALDI) has been considered as one of the most powerful analytical tools for mass spectrometry (MS) analysis of large molecular weight compounds such as proteins, nucleic acids, and synthetic polymers thanks to its high sensitivity, high resolution, and compatibility with high-throughput analysis. Despite these advantages, MALDI cannot be applied to MS analysis of small molecular weight compounds (<500 Da) because of the matrix interference in low mass region. Therefore, numerous efforts have been devoted to solving this issue by using metal, semi

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Denti, Vanna, Nicole Monza, Greta Bindi, et al. "6-Aza-2-Thiothymine as an Alternative Matrix for Spatial Proteomics with MALDI-MSI." International Journal of Molecular Sciences 25, no. 24 (2024): 13678. https://doi.org/10.3390/ijms252413678.

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Matrix Assisted Laser Desorption/Ionisation-Mass Spectrometry Imaging (MALDI-MSI) is a well-established spatial omic technique which enables the untargeted mapping of various classes of biomolecules, including tryptic peptides, directly on tissue. This method relies on the use of matrices for the ionisation and volatilisation of analytes, and α-Cyano-4-hydroxycinnamic acid (CHCA) represents the most widespread matrix for tryptic peptides analysis. However, CHCA also presents certain limitations that foster the quest for novel matrix compounds. 6-aza-2-thiothymine (ATT), traditionally used in M

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Monopoli, Antonio, Giovanni Ventura, Andrea Aloia, et al. "Synthesis and Investigation of Novel CHCA-Derived Matrices for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis of Lipids." Molecules 27, no. 8 (2022): 2565. http://dx.doi.org/10.3390/molecules27082565.

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A significant area of study and upgrading for increasing sensitivity and general performances of matrix-assisted laser-desorption ionization (MALDI) mass spectrometry (MS) is related to matrix design. Several efforts have been made to address the challenge of low-mass-region interference-free for metabolomics analysis and specifically for lipidomics. To this aim, rationally designed matrices as 4-chloro-α-cyanocinnamic acid (ClCCA) were introduced and reported to provide enhanced analytical performances. We have taken this rational design one step further by developing and optimizing new MALDI

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dos Santos, Nayara A., Lindamara M. de Souza, Fernanda E. Pinto, et al. "LDI and MALDI-FT-ICR imaging MS in Cannabis leaves: optimization and study of spatial distribution of cannabinoids." Analytical Methods 11, no. 13 (2019): 1757–64. http://dx.doi.org/10.1039/c9ay00226j.

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Дисертації з теми "Matrice MALDI"

Manuelli, Pascal. "Etude des mécanismes de la désorption : ionisation laser assistée par matrice." Metz, 1995. http://docnum.univ-lorraine.fr/public/UPV-M/Theses/1995/Manuelli.Pascal.SMZ9520.pdf.

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Ce mémoire sur les mécanismes de la désorption/ionisation laser assistée par matrice (MALDI) est le fruit de travaux réalisés au laboratoire de spectrométrie de masse et de chimie laser (LSMCL) de l'université de Metz. Cette thématique est apparue au laboratoire suite au développement de l'analyse des biomolécules par spectrométrie de masse et à l'expérience accumulée depuis 15 ans sur la désorption laser. Nous nous sommes attachés à décomposer les étapes constituant une analyse MALDI afin de mieux comprendre les mécanismes mis en jeu lors de ce type d'ionisation. Nous avons plus précisément,

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Jaber, Ali. "Matrices MALDI bithiophéniques spécifiques aux alcaloïdes : étude des mécanismes fondamentaux et applications." Thesis, Angers, 2017. http://www.theses.fr/2017ANGE0042/document.

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Mon travail de thèse a consisté à poursuivre le développement et l’application des matrices bithiophéniques spécifique aux alcaloïdes. Après l’optimisation d’un protocole efficace d’analyse, adapté à l’objectif de l’étude, la mise au point d’une méthode de dosage des alcaloïdes par MALDI dans des extraits végétaux et sans prétraitement préalable a été étudiée. Cette méthode a pu être validée en étudiant des alcaloïdes existant dans différents extraits des plantes toxiques. Ensuite, la synthèse et l’évaluation de nouveaux composés bithiophéniques ont été présentés de manière à évaluer les facte

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Lavigne, Damien. "Conception de surfaces de matrice extracellulaire analysables en spectrométrie de masse SELDI-TOF." Paris 7, 2008. http://www.theses.fr/2008PA077247.

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Notre projet a pour objectif de concevoir des surfaces de matrice extracellulaire (MEC) sur des chips analysables en spectrométrie de masse SELDI-TOF (Surface Enhanced Laser Desorption lonization Time Of Flight). La MEC est synthétisée directement par les cellules en culture sur les chips. Le décollement des cellules par un traitement permet ensuite d'obtenir une surface de MEC. Parmi les chips en aluminium commerciales, seules les surfaces de silice permettent la culture des cellules musculaires lisses (hCML) et endothéliales (HUVEC) humaines et d'obtenir de la MEC. La MEC de ces deux types c

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Xu, Zeyuan. "PTMomics : Microfluidics for post-translational modifications studies : application to glycoproteomics." Electronic Thesis or Diss., Université Paris sciences et lettres, 2023. http://www.theses.fr/2023UPSLS029.

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Les glycoprotéines jouent un rôle fondamental dans la vie. Des études récentes montrent qu'elle est largement présente dans les activités biologiques, telles que la liaison des récepteurs, la signalisation cellulaire, la réponse immunitaire, le repliement des protéines et l'action des hormones. Parallèlement, la glycosylation des protéines a été associée au pronostic et à l'évolution de maladies comme les cancers. Ainsi, elle devient un biomarqueur important, et est également significative pour le développement thérapeutique. La glycosylation mérite donc d'être étudiée en détail. La glycoproté

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Guerandel, Cyril. "Etude de la qualité du piégeage des matières organiques par la matrice cimentaire vis-à-vis de la lixiviation." Thesis, Metz, 2009. http://www.theses.fr/2009METZ030S/document.

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Dans le cadre de la qualité environnementale des matériaux, il est essentiel d'apporter la preuve que les matériaux à base de ciments adjuvantés ne relarguent pas ou peu de matières organiques lors de leur contact avec l'eau constituant une solution lixiviante. Les additifs organiques, tels que les agents de mouture et les superplastifiants, constituent deux classes d'adjuvants organiques utilisés de manière systématique dans la fabrication ou la formulation des matériaux cimentaires, notamment quand ils sont en contact avec l'eau potable (conduites et châteaux d'eau). Pour évaluer le piégeage

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Alves, Sandra. "Une échelle acido-basique pour une meilleure compréhension du rôle de la matrice dans la production d'ions multichargés : une approche thermo-cínétique de l'ionisation en mode MALDI." Paris 6, 2002. http://www.theses.fr/2002PA066005.

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Mallah, Khalil. "In depth systemic biology analysis of central nervous system injuries." Thesis, Lille 1, 2018. http://www.theses.fr/2018LIL1S108/document.

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Dans un contexte d’étude des altérations biologiques survenant après un impact sur le système nerveux central (SNC), ma thèse porte sur l’étude des modifications protéomiques et lipidiques survenant après une lésion du SNC. Une étude spatio-temporelle a été menée sur un modèle TBI de rat afin d'identifier des marqueurs spécifiques de la lésion. En utilisant le MALDI-MSI, nous avons effectués une reconstruction 3D du cerveau lésé 3 jours post-lésion et nous avons représentés les molécules lipidiques spécifiques à la lésion. Après, cette analyse est réalisé avec d’autres délais après l’impact: 1

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Crank, Jeffrey Aaron. "Ionic liquids MALDI-MS matrices and gas chromatography stationary phases /." [Ames, Iowa : Iowa State University], 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3379180.

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Hellwig, Nils [Verfasser]. "Das Laserablationsverhalten von ionischen Flüssigkeiten verschiedener MALDI-Matrices / Nils Hellwig." Kiel : Universitätsbibliothek Kiel, 2012. http://d-nb.info/1025465121/34.

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Allwood, Daniel Anthony. "Characterisation and ionisation modelling of matrices in MALDI mass spectrometry." Thesis, University of Hull, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301477.

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Книги з теми "Matrice MALDI"

Tambe, Suparna. Structure Performance Relationships of the Novel Maldi-MS Matrices. Logos Verlag Berlin, 2018.

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Maldi MS: A Practical Guide to Instrumentation, Methods, and Applications. Wiley-VCH Verlag GmbH, 2013.

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Hillenkamp, Franz, and Jasna Peter-Katalinic. Maldi MS: A Practical Guide to Instrumentation, Methods and Applications. Wiley & Sons, Limited, John, 2013.

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Hillenkamp, Franz, and Jasna Peter-Katalinic. Maldi MS: A Practical Guide to Instrumentation, Methods and Applications. Wiley & Sons, Incorporated, John, 2013.

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Hillenkamp, Franz, and Jasna Peter-Katalinic. Maldi MS: A Practical Guide to Instrumentation, Methods and Applications. Wiley & Sons, Incorporated, John, 2013.

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Hillenkamp, Franz, and Jasna Peter-Katalinic. Maldi MS: A Practical Guide to Instrumentation, Methods and Applications. Wiley & Sons, Incorporated, John, 2007.

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Hillenkamp, Franz, and Jasna Peter-Katalinic. Maldi MS: A Practical Guide to Instrumentation, Methods and Applications. Wiley & Sons, Limited, John, 2007.

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Hillenkamp, Franz, and Jasna Peter-Katalinic. Maldi MS: A Practical Guide to Instrumentation, Methods and Applications. Wiley & Sons, Incorporated, John, 2013.

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Riley, Peter. The role of the microbiology laboratory in antimicrobial stewardship. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198758792.003.0010.

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Microbiology laboratories play an important role in antimicrobial stewardship at the level of individual patients and the population as a whole. When empiric therapy has been started, rapid results can lead to earlier targeted treatment. Accumulated results of susceptibility tests can be analysed and used to generate local or national guidelines on empiric treatment and prophylaxis. Several methods can be used to determine microbial identity and antimicrobial susceptibility, including traditional culture-based methods and newer molecular methods such as matrix-assisted laser desorption ionizat

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Vargas-Fields, Cynthia. Microbial forensics: A qualitative analysis of Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight Mass Spectrometry (MALDI-TOF MS) on bioagent identification/characterization & its potential role in the attribution process of bioterrorist attacks. 2009.

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Частини книг з теми "Matrice MALDI"

Hossain, Mahmud, and Patrick A. Limbach. "A Comparison of MALDI Matrices." In Electrospray and MALDI Mass Spectrometry. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9780470588901.ch7.

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Bahr, U., and T. W. Jaskolla. "Employing ‘Second Generation’ Matrices." In Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-04819-2_1.

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Tucher, Joanna, Prasath Somasundaram, and Andreas Tholey. "Quantitative MALDI MS Using Ionic Liquid Matrices." In Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-04819-2_5.

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Santos, Cledir, Paula Galeano, Reginaldo Lima Neto, Manoel Marques Evangelista Oliveira, and Nelson Lima. "MALDI-TOF MS and its requirements for fungal identification." In Trends in the systematics of bacteria and fungi. CABI, 2021. http://dx.doi.org/10.1079/9781789244984.0119.

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Abstract Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) is now used as a routine technique for the fast and reliable identification of fungi at the species level and, currently, it represents an important phenotypic methodology based on proteomic profiles. The main limitations to MALDI-TOF MS for fungal identification are related to sample quality (e.g. quality of biological material such as rigidity or pigmentation of cell walls), sample preparation (e.g. the myriad of sample preparation methodologies that deliver different data sets to different M

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Towers, Mark W., and Rainer Cramer. "Ionic Liquids and Other Liquid Matrices for Sensitive MALDI MS Analysis." In Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-04819-2_3.

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Zhu, Yingdi, and Hubert H. Girault. "MALDI-TOF Mass Fingerprinting for Rapid Identification of Bacteria: Experimental Procedures." In Detection and Analysis of Microorganisms by Mass Spectrometry. Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/bk9781837670338-00027.

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In this chapter, scientific and instrumental fundamentals related to the generation of bacterial MALDI-TOF mass fingerprints were briefly described. For bacterial identification by MALDI-TOF mass fingerprinting, experimental procedures for patient sampling, the culture and isolation of bacterial cells from patient samples, the preparation of bacterial cells and MALDI matrices, and the deposition of bacteria and matrices on MALDI target plates, as well as the setting of instrumental parameters, were given in detail.

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Fukuyama, Yuko. "Liquid Matrices in MALDI-MS." In Applications of Ionic Liquids in Science and Technology. InTech, 2011. http://dx.doi.org/10.5772/24407.

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"Matrice d’actions." In Évaluation rapide de l’état de préparation du Mali au commerce électronique. UN, 2020. http://dx.doi.org/10.18356/4683b3b3-fr.

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Yang, Y. "MALDI-TOF Mass Fingerprinting for Rapid Identification of Bacteria: Data Analysis and Algorithm Development." In Detection and Analysis of Microorganisms by Mass Spectrometry. Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/bk9781837670338-00045.

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Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been widely used for identification of microorganisms. In a typical MALDI-TOF MS analysis of microorganisms, spectra of unknown samples are compared to reference libraries of spectra of known microorganisms by spectral pattern matching. This chapter provides an overview of the data analysis workflow for MALDI-TOF MS-based identification of microorganisms, including spectrum preprocessing, spectral matching, and result interpretation. The existing computational methods for the three steps of data ana

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Moszczyński, Adam. "Desorpcja/jonizacja laserowa wspomagana matrycą (MALDI)." In Proteomika i metabolomika. Warsaw University Press, 2010. http://dx.doi.org/10.31338/uw.9788323533399.pp.185-198.

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Тези доповідей конференцій з теми "Matrice MALDI"

Hahm, Tae-Hun, Wanyue Wang, Maxime Siegler, et al. "Comparative analysis of autofluorescence enhancement and MALDI imaging in the FluoMALDI pipeline using different matrix application methods: sublimation versus spraying." In Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXIII, edited by Attila Tarnok, Jessica P. Houston, and Xuantao Su. SPIE, 2025. https://doi.org/10.1117/12.3039138.

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Wang, Wanyue, Tae-Hun Hahm, Dalton R. Brown, et al. "Comparative analysis of fluorophore-MALDI matrix interactions in solid and liquid phases to investigate fluorescence enhancement effects in FluoMALDI imaging." In Reporters, Contrast Agents, and Molecular Probes for Biomedical Applications XVI, edited by Ramesh Raghavachari and Mikhail Y. Berezin. SPIE, 2025. https://doi.org/10.1117/12.3039312.

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Murray, Kermit K., Michelle D. Beeson, and David H. Russell. "Laser Ionization of Biomolecules in Solution." In Laser Applications to Chemical Analysis. Optica Publishing Group, 1994. http://dx.doi.org/10.1364/laca.1994.tha.5.

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Many powerful laser based methods are unavailable for the analysis of molecules in solution. Techniques for the analysis of liquids are particularly important for the study of biomolecules, whose natural environment is a water solution. Mass spectrometry is a powerful analytical technique, but liquids and mass spectrometers are fundamentally incompatible. We have developed a technique for laser ionization of biomolecules in solution by applying matrix-assisted laser desorption ionization (MALDI) to liquid aerosols. In the typical MALDI experiment, the analyte biomolecule is deposited from solu

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Kinsel, Gary R., Kent Gillig, Ricky Edmondson, and David H. Russell. "Fundamental Investigations of the Mechanism of Laser Desorption and Ionization in Matrix Assisted Laser Desorption / Ionization." In Laser Applications to Chemical Analysis. Optica Publishing Group, 1994. http://dx.doi.org/10.1364/laca.1994.thb.1.

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The recent development of Matrix Assisted Laser Desorption / Ionization (MALDI) has sparked a revolution in the field of high molecular weight mass spectrometry.1 Time-of-flight (TOF) mass spectra of proteins weighing up to 300,000 Da are now routinely produced and this achievement has fostered a variety of bioanalytical applications which were previously unapproachable using conventional mass spectrometric techniques. These successful applications have burgeoned in spite of a poor understanding of the mechanism of analyte desorption and ionization under MALDI conditions. An improved understan

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Bridgmohan, Chelsea, Lichang Wang, and Kristopher Kirmess. "INSIGHTS INTO PROTON TRANSFER MECHANISMS IN HALOGEN-SUBSTITUTED MALDI MATRICES." In 73rd International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2018. http://dx.doi.org/10.15278/isms.2018.wj10.

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Scott, C. T. J., C. Kosmidis, W. J. Jia, K. W. D. Ledingham, and R. P. Singhal. "Investigations of desorbed species from matrix materials used in MALDI." In The 7th international symposium: Resonance ionization spectroscopy 1994. AIP, 1995. http://dx.doi.org/10.1063/1.47635.

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Bridgmohan, Chelsea, Kristopher Kirmess, and Lichang Wang. "INSIGHT INTO THE CHARGE TRANSFER MECHANISMS OF HEAVY ATOM SUBSTITUTED MALDI MATRICES." In 72nd International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2017. http://dx.doi.org/10.15278/isms.2017.wi05.

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Kobylis, Paulina, Hanna Lis, Piotr Stepnowski, and Magda Caban. "Verification of the homogeneity of the matrix/analyte mixture on sample plate using MALDI-MS technique and new ionic liquid matrices." In Człowiek Nauka Środowisko. Institute of Biotechnology and Molecular Medicine Foundation, 2018. http://dx.doi.org/10.31708/spi3.18/pkoby.cns18.

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Drake, Wonder, Erin Seeley, and Richard Caprioli. "Matrix-Assisted Laser Desorption/Ionization (MALDI) Imaging Mass Spectrometry (IMS) Localize Mycobacterial Proteins To Sarcoidosis Granulomas." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3984.

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Hafenstine, Glenn. "Matrix-assisted Laser Desorption Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry for Advanced Polymer Charaterization." In 46th Polymeric Materials, Adhesives, and Composites (PolyMAC) Conference; KCNSC; June 21-23, 2022; KCNSC. US DOE, 2022. http://dx.doi.org/10.2172/1872439.

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Звіти організацій з теми "Matrice MALDI"

Puretzky, A. A., and D. B. Geohegan. LIF-imaging and gas-phase diagnostics of laser desorbed MALDI-matrix plumes. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/563317.

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Thurlow, James. 2018 Social Accounting Matrix for Mali: A Nexus Project SAM. International Food Policy Research Institute, 2021. http://dx.doi.org/10.2499/p15738coll2.134818.

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Korte, Andrew R. Development of matrix-assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) for plant metabolite analysis. Office of Scientific and Technical Information (OSTI), 2014. http://dx.doi.org/10.2172/1226566.

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Fluhr, Robert, and Maor Bar-Peled. Novel Lectin Controls Wound-responses in Arabidopsis. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7697123.bard.

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Innate immune responses in animals and plants involve receptors that recognize microbe-associated molecules. In plants, one set of this defense system is characterized by large families of TIR–nucleotide binding site–leucine-rich repeat (TIR-NBS-LRR) resistance genes. The direct interaction between plant proteins harboring the TIR domain with proteins that transmit and facilitate a signaling pathway has yet to be shown. The Arabidopsis genome encodes TIR-domain containing genes that lack NBS and LRR whose functions are unknown. Here we investigated the functional role of such protein, TLW1 (TI

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