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Статті в журналах з теми "Matrice MALDI"

Автор: Grafiati

Опубліковано: 22 грудня 2023

Оновлено: 31 липня 2025

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1

Rubakhin, Stanislav S., and Jonathan V. Sweedler. "Transparent triethylamine-containing MALDI matrices." Israel Journal of Chemistry 47, no. 2 (2007): 185–93. http://dx.doi.org/10.1560/ijc.47.2.185.

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2

Meier, Michael A. R., Nico Adams, and Ulrich S. Schubert. "Statistical Approach To Understand MALDI-TOFMS Matrices: Discovery and Evaluation of New MALDI Matrices." Analytical Chemistry 79, no. 3 (2007): 863–69. http://dx.doi.org/10.1021/ac061173v.

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3

HAZAMA, Hisanao, and Kunio AWAZU. "Matrices for MALDI Using an Infrared Laser." Journal of the Mass Spectrometry Society of Japan 64, no. 5 (2016): 183–86. http://dx.doi.org/10.5702/massspec.s16-38.

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4

Fresnais, Margaux, Esra Yildirim, Seda Karabulut, et al. "Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives." Molecules 26, no. 5 (2021): 1281. http://dx.doi.org/10.3390/molecules26051281.

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Анотація:

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has rarely been used in the field of therapeutic drug monitoring, partly because of the complexity of the ionization processes between the compounds to be quantified and the many MALDI matrices available. The development of a viable MALDI-MS method that meets regulatory guidelines for bioanalytical method validation requires prior knowledge of the suitability of (i) the MALDI matrix with the analyte class and properties for ionization, (ii) the crystallization properties of the MALDI matrix with automation features, and (

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5

FUKUYAMA, Yuko. "MALDI MS Analysis Using Liquid Matrices." Journal of the Mass Spectrometry Society of Japan 64, no. 5 (2016): 175–78. http://dx.doi.org/10.5702/massspec.s16-36.

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6

Lin, Chih-Hao, Chuping Lee, Yu-Cheng Wu, and I.-Chung Lu. "New Strategy to Preserve Phosphate by Ionic Liquid Matrices in Matrix-Assisted Laser Desorption/Ionization: A Case of Adenosine Nucleotides." Molecules 25, no. 5 (2020): 1217. http://dx.doi.org/10.3390/molecules25051217.

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Adenosine -5′-triphosphate (ATP) plays a valuable role in metabolic activity to produce adequate energy in a biosystem. A high ATP/AMP ratio has a correlation with diabetes that induces suppression of AMP-activated protein kinase (AMPK). Matrix-assisted laser desorption/ionization (MALDI)–mass spectrometry (MS) has outstanding potential in determining the ratio of several types of adenosine phosphates in a sample to rapidly understand the primary energy transfer in metabolism. Although MALDI is viewed as a soft ionization technique for MS analysis, excess photon energy might crack the phosphat

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7

Kim, Seung-Woo, Sunbum Kwon, and Young-Kwan Kim. "Graphene Oxide Derivatives and Their Nanohybrid Structures for Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Analysis of Small Molecules." Nanomaterials 11, no. 2 (2021): 288. http://dx.doi.org/10.3390/nano11020288.

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Анотація:

Matrix-assisted laser desorption/ionization (MALDI) has been considered as one of the most powerful analytical tools for mass spectrometry (MS) analysis of large molecular weight compounds such as proteins, nucleic acids, and synthetic polymers thanks to its high sensitivity, high resolution, and compatibility with high-throughput analysis. Despite these advantages, MALDI cannot be applied to MS analysis of small molecular weight compounds (<500 Da) because of the matrix interference in low mass region. Therefore, numerous efforts have been devoted to solving this issue by using metal, semi

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8

Denti, Vanna, Nicole Monza, Greta Bindi, et al. "6-Aza-2-Thiothymine as an Alternative Matrix for Spatial Proteomics with MALDI-MSI." International Journal of Molecular Sciences 25, no. 24 (2024): 13678. https://doi.org/10.3390/ijms252413678.

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Matrix Assisted Laser Desorption/Ionisation-Mass Spectrometry Imaging (MALDI-MSI) is a well-established spatial omic technique which enables the untargeted mapping of various classes of biomolecules, including tryptic peptides, directly on tissue. This method relies on the use of matrices for the ionisation and volatilisation of analytes, and α-Cyano-4-hydroxycinnamic acid (CHCA) represents the most widespread matrix for tryptic peptides analysis. However, CHCA also presents certain limitations that foster the quest for novel matrix compounds. 6-aza-2-thiothymine (ATT), traditionally used in M

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9

Monopoli, Antonio, Giovanni Ventura, Andrea Aloia, et al. "Synthesis and Investigation of Novel CHCA-Derived Matrices for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis of Lipids." Molecules 27, no. 8 (2022): 2565. http://dx.doi.org/10.3390/molecules27082565.

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A significant area of study and upgrading for increasing sensitivity and general performances of matrix-assisted laser-desorption ionization (MALDI) mass spectrometry (MS) is related to matrix design. Several efforts have been made to address the challenge of low-mass-region interference-free for metabolomics analysis and specifically for lipidomics. To this aim, rationally designed matrices as 4-chloro-α-cyanocinnamic acid (ClCCA) were introduced and reported to provide enhanced analytical performances. We have taken this rational design one step further by developing and optimizing new MALDI

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10

dos Santos, Nayara A., Lindamara M. de Souza, Fernanda E. Pinto, et al. "LDI and MALDI-FT-ICR imaging MS in Cannabis leaves: optimization and study of spatial distribution of cannabinoids." Analytical Methods 11, no. 13 (2019): 1757–64. http://dx.doi.org/10.1039/c9ay00226j.

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11

Sanhueza, Claudia, Nathalia Baptista Dias, Daniela Vergara, Lisette Silva, Emigdio Chávez-Ángel, and Alejandro Castro-Alvarez. "Improving Sensitivity and Resolution of Dendrimer Identification in MALDI-TOF Mass Spectrometry Using Varied Matrix Combinations." Polymers 17, no. 2 (2025): 219. https://doi.org/10.3390/polym17020219.

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Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a well-known technique for polymer analysis, particularly for determining the molecular weight and structural details of dendrimers. In this study, we evaluated the performance of various matrices, such as 2′,4′,6′-trihydroxyacetophenone (THAP), α-cyano-4-hydroxycinnamic acid (HCCA), and sinapinic acid (SA), and their combinations, on the sensitivity and resolution of poly(amidoamine) (PAMAM) dendrimers of different generations (G3.0, G4.0, and G5.0). Our results demonstrated that the combination of

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12

Weißflog, Jerrit, and Aleš Svatoš. "1,8-Di(piperidinyl)-naphthalene – rationally designed MAILD/MALDI matrix for metabolomics and imaging mass spectrometry." RSC Advances 6, no. 79 (2016): 75073–81. http://dx.doi.org/10.1039/c6ra17237g.

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13

Kobylis, Paulina, Hanna Lis, Piotr Stepnowski, and Magda Caban. "Spectroscopic verification of ionic matrices for MALDI analysis." Journal of Molecular Liquids 284 (June 2019): 328–42. http://dx.doi.org/10.1016/j.molliq.2019.03.137.

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14

Warren, Alexander D., David J. Mitchell, and Paul J. Gates. "Methodologies for the airbrush application of MALDI matrices." European Journal of Mass Spectrometry 24, no. 1 (2018): 89–95. http://dx.doi.org/10.1177/1469066717750031.

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15

Ali, Arslan, Najia Shahid, and Syed Ghulam Musharraf. "Application of dyes as doping agents in MALDI-MS matrices for the signal enhancement of proteins." RSC Advances 7, no. 11 (2017): 6598–604. http://dx.doi.org/10.1039/c6ra27156a.

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16

Leopold, Jenny, Yulia Popkova, Kathrin Engel, and Jürgen Schiller. "Recent Developments of Useful MALDI Matrices for the Mass Spectrometric Characterization of Lipids." Biomolecules 8, no. 4 (2018): 173. http://dx.doi.org/10.3390/biom8040173.

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Анотація:

Matrix-assisted laser desorption/ionization (MALDI) is one of the most successful “soft” ionization methods in the field of mass spectrometry and enables the analysis of a broad range of molecules, including lipids. Although the details of the ionization process are still unknown, the importance of the matrix is commonly accepted. Both, the development of and the search for useful matrices was, and still is, an empirical process, since properties like vacuum stability, high absorption at the laser wavelength, etc. have to be fulfilled by a compound to become a useful matrix. This review provid

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17

Zechmann, Carsten, Tassilo Muskat, and Jürgen Grotemeyer. "Wavelength- and Time-Resolved Luminescence Spectroscopy for Investigation of the Matrix-Assisted Laser Desorption Process." European Journal of Mass Spectrometry 8, no. 4 (2002): 287–93. http://dx.doi.org/10.1255/ejms.490.

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This work deals with investigations of fluorescence phenomena during interaction of ultraviolet laser radiation with four substances (2,5-dihydroxybenzoic acid, 3-hydroxypicolinic acid, dithranol and ferulic acid) commonly used as matrices in matrix-assisted laser desorption/ionization (MALDI). Wavelength-resolved fluorescence measurements allowed classification of UV-MALDI matrices on the basis of their Stokes shift. Matrices showing a high Stokes shift dissipated high amounts of laser energy by means of intra- and intermolecular energy transfer processes, hence contributing less to the ioniz

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18

Ling, Ling, Chunsheng Xiao, Liyan Jiang, et al. "A cool and high salt-tolerant ionic liquid matrix for preferential ionization of phosphopeptides by negative ion MALDI-MS." New J. Chem. 41, no. 20 (2017): 12241–49. http://dx.doi.org/10.1039/c7nj01706e.

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19

Damnjanovic, Bojana, Biljana Petrovic, Jasmina Dimitric-Markovic, and Marijana Petkovic. "Comparison of MALDI-TOF mass spectra of [PdCl(dien)]Cl and [Ru(en)2Cl2]Cl acquired with different matrices." Journal of the Serbian Chemical Society 76, no. 12 (2011): 1687–701. http://dx.doi.org/10.2298/jsc110201145d.

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Анотація:

In this work, the matrix-assisted laser desorption and ionization time-of-flight (MALDI-TOF) mass spectra of two cationic complexes, i.e., [PdCl(dien)]Cl and [Ru(en)2Cl2]Cl, acquired under different conditions were analyzed. The spectra were recorded with three matrices with or without trifluoroacetic acid (TFA), i.e., two traditional matrices, i.e., 2,5-dihydroxybenzoic acid and ?-cyano-hydroxycinnamic acid, and one flavonoid, quercetin. The spectra acquired with quercetin appeared to be the simplest, whereas in the spectra obtained with other matrices, peaks arising either from the addition

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20

Kosyakov, Dmitry S., Elena A. Anikeenko, Nikolay V. Ul’yanovskii, Oleg Yu Khoroshev, Irina S. Shavrina, and Natalya S. Gorbova. "Ionic liquid matrices for MALDI mass spectrometry of lignin." Analytical and Bioanalytical Chemistry 410, no. 28 (2018): 7429–39. http://dx.doi.org/10.1007/s00216-018-1353-7.

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21

SRINIVASAN, N., CAROL A. HANEY, JONATHAN S. LINDSEY, WENZHU ZHANG, and BRIAN T. CHAIT. "Investigation of MALDI-TOF Mass Spectrometry of Diverse Synthetic Metalloporphyrins, Phthalocyanines and Multiporphyrin Arrays." Journal of Porphyrins and Phthalocyanines 03, no. 04 (1999): 283–91. http://dx.doi.org/10.1002/(sici)1099-1409(199904)3:4<283::aid-jpp132>3.0.co;2-f.

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We investigated the utility of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) for analyzing porphyrinic compounds using a variety of different synthetic porphyrins, azaporphyrins, phthalocyanines and multiporphyrin arrays. Comparisons of spectra obtained from these analytes deposited either as neat samples or codeposited with neutral or acidic matrices have been made with the goal of identifying conditions that yield minimal demetalation, transmetalation, adduct formation and fragmentation. It was found that the molecular masses of many porphyrins c

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22

Livet, Sandrine, Sylvia Worbs, Hervé Volland, et al. "Development and Evaluation of an Immuno-MALDI-TOF Mass Spectrometry Approach for Quantification of the Abrin Toxin in Complex Food Matrices." Toxins 13, no. 1 (2021): 52. http://dx.doi.org/10.3390/toxins13010052.

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The toxin abrin found in the seeds of Abrus precatorius has attracted much attention regarding criminal and terroristic misuse over the past decade. Progress in analytical methods for a rapid and unambiguous identification of low abrin concentrations in complex matrices is essential. Here, we report on the development and evaluation of a MALDI-TOF mass spectrometry approach for the fast, sensitive and robust abrin isolectin identification, differentiation and quantification in complex food matrices. The method combines immunoaffinity-enrichment with specific abrin antibodies, accelerated tryps

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23

Zambonin, Carlo. "MALDI-TOF Mass Spectrometry Applications for Food Fraud Detection." Applied Sciences 11, no. 8 (2021): 3374. http://dx.doi.org/10.3390/app11083374.

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Chemical analysis of food products relating to the detection of the most common frauds is a complex task due to the complexity of the matrices and the unknown nature of most processes. Moreover, frauds are becoming more and more sophisticated, making the development of reliable, rapid, cost-effective new analytical methods for food control even more pressing. Over the years, MALDI-TOF MS has demonstrated the potential to meet this need, also due to a series of undeniable intrinsic advantages including ease of use, fast data collection, and capability to obtain valuable information even from co

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24

Padilla Jaramillo, Carlos A., Luis M. Díaz Sánchez, Marianny Y. Combariza Montañez, Cristian Blanco Tirado, and Aldo F. Combariza Montañez. "Photon Harvesting Molecules: Ionization Potential from Quantum Chemical Calculations of Phytoplanktonic Pigments for MALDI-MS Analysis." Orinoquia 25, no. 1 (2021): 13–23. http://dx.doi.org/10.22579/20112629.676.

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The Ionization Potential (IP) of chemical species is of paramount importance for the Matrix Assisted Laser Desorption/Ionization (MALDI) analyticaltechnique. Specifically, IPs are used in MALDI MS Electron Transfer (ET) as a parameter to select the matrix for a given family of chemical species. We useda quantum chemical methodology to computationally determine IPs for a set of photosensible phytoplanktonic pigments. These calculations could be used as a guide for MALDI matrix selection. IPs were determined using Koopman’s Theorem, via Geometry Optimization and Single Point Energy within the Re

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25

Zhao, Zhenwen, Shaoxiang Xiong, Xiangwen Liu, Bin Xin, and Guanghui Wang. "Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Studies of Low Molecular Weight Dendrimers." European Journal of Mass Spectrometry 9, no. 3 (2003): 203–11. http://dx.doi.org/10.1255/ejms.547.

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Анотація:

We report the application of matrix-assisted laser desorption/ionization time-of-flight (MALDI-ToF) mass spectrometry, with delayed extraction in the reflectron mode, for the characterization of low molecular weight dendrimers. 20 dendrimer samples were measured and 4 typical dendrimers, as examples, are discussedin detail. Several factors that affect the analysis including the matrices used, the concentrations of sample, the solvents and cationization reagent used, were investigated in detail. Experimental results indicate that the type of solvent can greatly influence exact mass measurement.

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26

Koudelka, Štěpán, Tereza Gelbíčová, Markéta Procházková, and Renáta Karpíšková. "Lineage and serotype identification of Listeria monocytogenes by matrix-assisted laser desorption ionization-time of flight mass spectrometry." Czech Journal of Food Sciences 36, No. 6 (2019): 452–58. http://dx.doi.org/10.17221/87/2018-cjfs.

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The identification of Listeria species, lineages and serotypes remains a crucial issue not only in epidemic surveys, but also in monitoring of the diversity of bacteria in the food chain. The aim of this study was identification of L. monocytogenes strains at lineage and serotype level using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). The performance of MALDI-TOF MS was tested to identify L. monocytogenes into two lineages (I and II) and four serotypes (1/2a, 1/2b, 1/2c and 4b) the most commonly found in humans and food. Total of 227 L. monocyto

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27

Kouvonen, Petri, Eeva M. Rainio, Veronika Suni, Päivi Koskinen, and Garry L. Corthals. "Data combination from multiple matrix-assisted laser desorption/ionization (MALDI) matrices: opportunities and limitations for MALDI analysis." Rapid Communications in Mass Spectrometry 24, no. 23 (2010): 3493–95. http://dx.doi.org/10.1002/rcm.4785.

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28

Ugarov, Michael V., T. Egan, Dmitry V. Khabashesku, et al. "MALDI Matrices for Biomolecular Analysis Based on Functionalized Carbon Nanomaterials." Analytical Chemistry 76, no. 22 (2004): 6734–42. http://dx.doi.org/10.1021/ac049192x.

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29

Somogyi, Árpád, El Hadj Elandaloussi, Douglas E. Hall, Anne Buyle Padías, Robert B. Bates, and H. K. Hall. "Powerfully Solvating Matrices for MALDI-TOF Spectroscopy of Aromatic Polyesters." Macromolecules 40, no. 15 (2007): 5311–21. http://dx.doi.org/10.1021/ma062200m.

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30

Calvano, Cosima Damiana, Antonio Monopoli, Tommaso R. I. Cataldi, and Francesco Palmisano. "MALDI matrices for low molecular weight compounds: an endless story?" Analytical and Bioanalytical Chemistry 410, no. 17 (2018): 4015–38. http://dx.doi.org/10.1007/s00216-018-1014-x.

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31

Sholokhova, Anastasiya Yu, Svetlana A. Borovikova, Sergey A. Prikhod'ko, and Alexey K. Buryak. "Ionization of ionic liquids under laser desorption/ionization." Сорбционные и хроматографические процессы 20, no. 5 (2020): 565–71. http://dx.doi.org/10.17308/sorpchrom.2020.20/3048.

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Despite various studies of ILs as MALDI matrices, however, so far no relationship has been foundbetween the composition of ILs and their ability to serve as «good» matrices. For a preliminary experiment,in order to evaluate the characteristics of ILs before being used as a matrix in MALDI-MS, it is necessary tostudy the mass spectral behavior for the matrices themselves under LDI conditions. Therefore, the purpose of this work was to analyse ion liquids based on the cation imidazolium in combination with different types ofanions by the LDI method. Ionic liquids were synthesized in the Laborato

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32

Sagandykova, Gulyaim, Justyna Walczak-Skierska, Fernanda Monedeiro, Paweł Pomastowski, and Bogusław Buszewski. "New Methodology for the Identification of Metabolites of Saccharides and Cyclitols by Off-Line EC-MALDI-TOF-MS." International Journal of Molecular Sciences 21, no. 15 (2020): 5265. http://dx.doi.org/10.3390/ijms21155265.

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A combination of electrochemistry (EC) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (off-line EC-MALDI-TOF-MS) was applied for determination of the studied biologically active compounds (D-glucose, D-fructose, D-galactose, D-pinitol, L-chiro-inositol, and myo-inositol) and their possible electrochemical metabolites. In this work, boron-doped diamond electrode (BDD) was used as a working electrode. MALDI-TOF-MS experiments were carried out (both in positive and negative ion modes and using two matrices) to identify the structures of electrochemical products.

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33

Veloso, Antonio, and Rebeca Sola-Llano. "MALDI-TOF masa espektrometriaren erabilera polimeroak ezaugarritzeko." EKAIA Euskal Herriko Unibertsitateko Zientzia eta Teknologia Aldizkaria, no. 35 (May 2, 2019): 185–96. http://dx.doi.org/10.1387/ekaia.19691.

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Анотація:

Gaur egun, materialak ezaugarritzekoerabiltzen diren teknikek informazio dezente uzten dute agerian, baina oraindik nahiko zaila da egiturari buruzko informazio osatua lortzea. Informazio hau garrantzi handikoa eta beharrezkoa da modu sakon batean polimero horietatik eratorritako materialen propietateak ezagutzeko. Polimeroak karakterizatzeko, Matrix Assisted Laser Desorption-Ionization Time of Flight Mass Spectrometry (MALDI/TOF MS) sortu zenetik, gero eta gehiago hedatu da teknika honen erabilera arlo desberdinetan.Masa-espektrometria teknika hau hedatu egin da polimeroen karakterizazioan, m

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34

Barada, Erina, and Hiroshi Hinou. "BOA/DHB/Na: An Efficient UV-MALDI Matrix for High-Sensitivity and Auto-Tagging Glycomics." International Journal of Molecular Sciences 23, no. 20 (2022): 12510. http://dx.doi.org/10.3390/ijms232012510.

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Matrix selection is a critical factor for success in glycomics studies using matrix-assisted laser desorption/ionization–mass spectrometry (MALDI–MS). In this study, we evaluated and optimized a new solid ionic matrix—O-benzylhydroxylamine (BOA)/2,5-dihydroxybenzoic acid (DHB)/Na—containing BOA and a small amount of sodium as the counter salt of DHB. The concentration of a mixture of BOA/DHB/Na and glycans on a MALDI target plate led to O-benzyloxy tagging of the reducing ends of the glycans. The BOA/DHB/Na matrix showed excellent aggregation performance and the ability to form a homogeneous s

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35

Fresnais, Margaux, Seda Karabulut, Yasmin Abou Zeed, et al. "Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices—A Practical Example." Molecules 27, no. 3 (2022): 690. http://dx.doi.org/10.3390/molecules27030690.

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Анотація:

Desorption/ionization mass spectrometry (DI-MS) approaches allow for the rapid quantification of drugs in biological matrices using assays that can be validated according to regulatory guidelines. However, specific adaptations must be applied to create reliable quantification methods, depending on the approach and instrumentation used. In the present article, we demonstrate the importance of the molecular weight, the fragmentation pattern, and the purity of the internal standard for the development of matrix-assisted laser desorption/ionization (MALDI)-ion mobility (IM)-tandem MS and MS/MS met

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36

Lin, Hou-Yu, Hsu Chen Hsu, I.-Chung Lu, et al. "Fluorescence spectroscopy of UV-MALDI matrices and implications of ionization mechanisms." Journal of Chemical Physics 141, no. 16 (2014): 164307. http://dx.doi.org/10.1063/1.4898372.

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37

Wang, Xiaodong, Jun Han, Albert Chou, Juncong Yang, Jingxi Pan, and Christoph H. Borchers. "Hydroxyflavones as a New Family of Matrices for MALDI Tissue Imaging." Analytical Chemistry 85, no. 15 (2013): 7566–73. http://dx.doi.org/10.1021/ac401595a.

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38

Giménez, Estela, Fernando Benavente, José Barbosa, and Victoria Sanz-Nebot. "Ionic liquid matrices for MALDI-TOF-MS analysis of intact glycoproteins." Analytical and Bioanalytical Chemistry 398, no. 1 (2010): 357–65. http://dx.doi.org/10.1007/s00216-010-3898-y.

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Khajavinia, Amir, and Anas El-Aneed. "Carbon-Based Nanoparticles and Their Surface-Modified Counterparts as MALDI Matrices." Analytical Chemistry 95, no. 1 (2023): 100–114. http://dx.doi.org/10.1021/acs.analchem.2c04537.

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Ehring, H., and B. U. R. Sundqvist. "Excited state relaxation processes of MALDI-matrices studied by luminescence spectroscopy." Applied Surface Science 96-98 (April 1996): 577–80. http://dx.doi.org/10.1016/0169-4332(95)00534-x.

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Li, Ying L., and Michael L. Gross. "Ionic-liquid matrices for quantitative analysis by MALDI-TOF mass spectrometry." Journal of the American Society for Mass Spectrometry 15, no. 12 (2004): 1833–37. http://dx.doi.org/10.1016/j.jasms.2004.08.011.

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Castellanos-García, Laura J., Brian Castro Agudelo, Hernando F. Rosales, et al. "Oligo p-Phenylenevinylene Derivatives as Electron Transfer Matrices for UV-MALDI." Journal of The American Society for Mass Spectrometry 28, no. 12 (2017): 2548–60. http://dx.doi.org/10.1007/s13361-017-1783-z.

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Horváth, B., F. Peles, A. Szél, et al. "Molecular typing of foodborne coagulase-positive Staphylococcus isolates identified by MALDI-TOF MS." Acta Alimentaria 49, no. 3 (2020): 307–13. http://dx.doi.org/10.1556/066.2020.49.3.9.

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The aim of the study was the identification and characterisation of coagulase-positive Staphylococcus bacteria obtained from food matrices by mass spectrometry and molecular methods. A total of 46 coagulase-positive Staphylococcus isolates were collected from different foodstuffs. The Staphylococcus isolates were identified by MALDI-TOF MS and confirmed by the presence and sequence analysis of the Staphylococcus protein A gene. Staphylococcal enterotoxin genes were also investigated by multiplex PCR. Based on the identification of strains by the MALDI-TOF MS technique and spa-typing, all strai

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44

ERRA-BALSELLS, Rosa, and Hiroshi NONAMI. "UV-MALDI-TOF MS Analysis of Carbohydrates. Reviewing Comparative Studies Performed Using nor-Harmane and Classical UV-MALDI Matrices." Environment Control in Biology 46, no. 2 (2008): 65–90. http://dx.doi.org/10.2525/ecb.46.65.

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Bianco, Mariachiara, Giovanni Ventura, Cosima Damiana Calvano, Ilario Losito, Tommaso R. I. Cataldi, and Antonio Monopoli. "Matrix Selection Strategies for MALDI-TOF MS/MS Characterization of Cyclic Tetrapyrroles in Blood and Food Samples." Molecules 29, no. 4 (2024): 868. http://dx.doi.org/10.3390/molecules29040868.

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Cyclic tetrapyrrole derivatives such as porphyrins, chlorins, corrins (compounds with a corrin core), and phthalocyanines are a family of molecules containing four pyrrole rings usually coordinating a metal ion (Mg, Cu, Fe, Zn, etc.). Here, we report the characterization of some representative cyclic tetrapyrrole derivatives by MALDI-ToF/ToF MS analyses, including heme b and c, phthalocyanines, and protoporphyrins after proper matrix selection. Both neutral and acidic matrices were evaluated to assess potential demetallation, adduct formation, and fragmentation. While chlorophylls exhibited ma

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46

Huang, Jun-Kai, Yi-Wen Hsiao, Wen-Chi Chen, and Sarah Y. Chang. "Nylon Membrane-Based Electromembrane Extraction Coupled with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for the Determination of Insulin." Separations 9, no. 10 (2022): 286. http://dx.doi.org/10.3390/separations9100286.

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A rapid and sensitive protein determination method that uses electromembrane extraction (EME) and is coupled with matrix-assisted laser desorption/ionization mass spectrometry (MALDI/MS) is developed. A flat nylon membrane is used to collect proteins from an aqueous solution and is directly analyzed by MALDI/MS after the addition of the MALDI matrix. Insulin is used as a model protein to investigate the optimum extraction of the parameters. The optimum EME conditions are obtained at 12 V of voltage, 10 min of extraction time, 12 mL sample volume, and 400 rpm agitation rate. The linear dynamic

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Novaconi, Cristina Ramona, Robert Onulov, Alina Florina Serb, et al. "Assessing Glycosphingolipid Profiles in Human Health and Disease Using Non-Imaging MALDI Mass Spectrometry." Applied Sciences 13, no. 17 (2023): 9922. http://dx.doi.org/10.3390/app13179922.

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Glycosphingolipids (GSLs) are a glycolipid subtype which plays vital roles in numerous biological processes, cell–cell interactions, as well as oncogenesis and ontogenesis. They are ubiquitous molecules found mostly in cell membranes. Abnormal expression of GSLs as well as altered molecular structure have been linked with progression of cancer and metastasis and are involved in the pathophysiology of neurodegenerative, autoimmune, and infectious diseases as well as inherited enzyme defects—glycosphingolipidoses. Matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) plays a l

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Park, Jun Won, Geon Kook Lee, Hee Seok Lee, et al. "Histology differentiation in non-small cell lung cancer using matrix-assisted laser desorption/ionization mass spectrometry." Journal of Clinical Oncology 30, no. 15_suppl (2012): e21043-e21043. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e21043.

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e21043 Background: New developments in the treatment of lung cancer have necessitated the correct histologic differentiation between two major histologic types of NSCLC. Methods: Histology-directed tissue matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) has been demonstrated to be useful for molecular profiling of common solid tumors. In this approach, mass spectra are obtained from discrete locations on the thin sections of frozen tissues sections. In this study, we evaluated various MALDI MS protocols for the histopathologic classification of NSCLC. Results: When ad

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Monopoli, Antonio, Angelo Nacci, Tommaso R. I. Cataldi та Cosima D. Calvano. "Synthesis and Matrix Properties of α-Cyano-5-phenyl-2,4-pentadienic Acid (CPPA) for Intact Proteins Analysis by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry". Molecules 25, № 24 (2020): 6054. http://dx.doi.org/10.3390/molecules25246054.

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The effectiveness of a synthesized matrix, α-cyano-5-phenyl-2,4-pentadienic acid (CPPA), for protein analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) in complex samples such as foodstuff and bacterial extracts, is demonstrated. Ultraviolet (UV) absorption along with laser desorption/ionization mass spectrometry (LDI-MS) experiments were systematically conducted in positive ion mode under standard Nd:YLF laser excitation with the aim of characterizing the matrix in terms of wavelength absorption and proton affinity. Besides, the results for

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De León, Tobías Schmidt, María L. Salum, and Rosa Erra-Balsells. "Thermal stability of ionic matrices for MALDI-MS. A comparative study in solid state with classical matrices." Thermochimica Acta 749 (July 2025): 180004. https://doi.org/10.1016/j.tca.2025.180004.

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