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Статті в журналах з теми "Microfluidic spinning":

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Kazemzadeh, Amin, P. Ganesan, Fatimah Ibrahim, Lawrence Kulinsky, and Marc J. Madou. "Guided routing on spinning microfluidic platforms." RSC Advances 5, no. 12 (2015): 8669–79. http://dx.doi.org/10.1039/c4ra14397c.

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A robust two stage passive microvalve is devised that can be used for (a) changing the flow direction continuously from one direction to another, and (b) liquid/particle distribution in centrifugal microfluidics.
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Zhang, Wei, Chengyi Hou, Yaogang Li, Qinghong Zhang, and Hongzhi Wang. "Microfluidic spinning of editable polychromatic fibers." Journal of Colloid and Interface Science 558 (January 2020): 115–22. http://dx.doi.org/10.1016/j.jcis.2019.09.113.

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Gursoy, Akin, Kamran Iranshahi, Kongchang Wei, Alexis Tello, Efe Armagan, Luciano F. Boesel, Fabien Sorin, René M. Rossi, Thijs Defraeye, and Claudio Toncelli. "Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers." Polymers 12, no. 3 (March 10, 2020): 633. http://dx.doi.org/10.3390/polym12030633.

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Microfluidic wet spinning has gained increasing interest in recent years as an alternative to conventional wet spinning by offering higher control in fiber morphology and a gateway for the development of multi-material fibers. Conventionally, microfluidic chips used to create such fibers are fabricated by soft lithography, a method that requires both time and investment in necessary cleanroom facilities. Recently, additive manufacturing techniques were investigated for rapid and cost-efficient prototyping. However, these microfluidic devices are not yet matching the resolutions and tolerances offered by soft lithography. Herein, we report a facile and rapid method using selected arrays of hypodermic needles as templates within a silicone elastomer matrix. The produced microfluidic spinnerets display co-axially aligned circular channels. By simulation and flow experiments, we prove that these devices can maintain laminar flow conditions and achieve precise 3D hydrodynamic focusing. The devices were tested with a commercial polyurethane formulation to demonstrate that fibers with desired morphologies can be produced by varying the degree of hydrodynamic focusing. Thanks to the adaptability of this concept to different microfluidic spinneret designs—as well as to its transparency, ease of fabrication, and cost-efficient procedure—this device sets the ground for transferring microfluidic wet spinning towards industrial textile settings.
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Shi, Xuetao, Serge Ostrovidov, Yihua Zhao, Xiaobin Liang, Motohiro Kasuya, Kazue Kurihara, Ken Nakajima, Hojae Bae, Hongkai Wu, and Ali Khademhosseini. "Microfluidic Spinning of Cell-Responsive Grooved Microfibers." Advanced Functional Materials 25, no. 15 (February 26, 2015): 2250–59. http://dx.doi.org/10.1002/adfm.201404531.

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Chang, Yaw-Jen, Shia-Chung Chen, and Cheng-Li Hsu. "Study on Microchannel Design and Burst Frequency Detection for Centrifugal Microfluidic System." Advances in Materials Science and Engineering 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/137347.

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A centrifugal microfluidic system has been developed in this study, enabling the control and measurement of the burst frequency in order to manipulate the liquid. The radial microfluid chips with different microchannel dimensions were designed for simulation analyses and experimental verifications. The microfluidic flow in the microchannel was analyzed using software CFDRC, providing an accurate result compared with that from experiment. The results show that the design of the overflow microchannel can correctly keep the liquid volume with error as low as 5%. For mercurochrome, the burst frequency has an inverse proportion to the channel width, and the simulation results agree with the experimental results. For oil, however, the experimental and simulation results indicate that the relationship between the burst frequency and channel width is not obvious due to oil properties. Since the simulation approach can provide an accurate prediction of flow behavior in the microchannel, the design of radial microfluid chip and the control of burst frequency can be achieved effectively. A practical application to design the centrifugal microfluidic disc for blood typing test was also carried out in this study. The centrifugal microfluidic system can successfully control the spinning speed to achieve the result of adding reagents in a specific sequence.
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Hofmann, Eddie, Kilian Krüger, Christian Haynl, Thomas Scheibel, Martin Trebbin, and Stephan Förster. "Microfluidic nozzle device for ultrafine fiber solution blow spinning with precise diameter control." Lab on a Chip 18, no. 15 (2018): 2225–34. http://dx.doi.org/10.1039/c8lc00304a.

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Honaker, Lawrence W., Shameek Vats, Manos Anyfantakis, and Jan P. F. Lagerwall. "Elastic sheath–liquid crystal core fibres achieved by microfluidic wet spinning." Journal of Materials Chemistry C 7, no. 37 (2019): 11588–96. http://dx.doi.org/10.1039/c9tc03836a.

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Guo, Yongshi, Jianhua Yan, John H. Xin, Lihuan Wang, Xi Yu, Longfei Fan, Peifeng Liu, and Hui Yu. "Microfluidic-directed biomimetic Bulbine torta-like microfibers based on inhomogeneous viscosity rope-coil effect." Lab on a Chip 21, no. 13 (2021): 2594–604. http://dx.doi.org/10.1039/d1lc00252j.

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Li, Jiaxuan, Yu Li, Xuedi Zhang, Song Miao, Mingqian Tan, and Wentao Su. "Microfluidic spinning of fucoxanthin-loaded nanofibers for enhancing antioxidation and clarification of fruit juice." Food & Function 13, no. 3 (2022): 1472–81. http://dx.doi.org/10.1039/d1fo03766h.

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Zhao, Y., G. Czilwik, V. Klein, K. Mitsakakis, R. Zengerle, and N. Paust. "C-reactive protein and interleukin 6 microfluidic immunoassays with on-chip pre-stored reagents and centrifugo-pneumatic liquid control." Lab on a Chip 17, no. 9 (2017): 1666–77. http://dx.doi.org/10.1039/c7lc00251c.

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Дисертації з теми "Microfluidic spinning":

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Li, David. "Biomimetic modifications to microfluidic silk spinning." Thesis, Boston University, 2014. https://hdl.handle.net/2144/21205.

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Thesis (M.Sc.Eng.) PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.
Silk fibers from arthropods possess several favorable properties for biomedical applications, including high mechanical strength and biocompatibility. However, the majority of silk fiber production is currently limited to manipulation of cocoons from the Bombyxmori silkworm. The efficiency of the process can be increased by dissolving waste silk threads and using artificial spinning techniques to spin the proteins back into usable fibers. Once an artificial spinning technique has been perfected, it may be possible to use similar designs to spin recombinant silk proteins into threads with more favorable mechanical properties. The first step towards customizable silk is to artificially spin silk protein into fibers with comparable properties to naturally-derived silk threads. Current microfluidic devices are limited to spinning B. mori silk into weak, poorly-formed fibers. The incorporation of silk gland-like ion gradients and high shear stress into current and novel microfluidic devices is theorized to improve mechanical properties of resultant spun silk. To this end, ion gradients were added to the current microfluidic device. In addition, a novel microfluidic device was developed to increase shear stress. After investigating the individual effects of ion gradients and shear stress on the silk spinning process, an integrated microfluidic device was designed to investigate the combined effects. Computational models of the flow within each microfluidic device were generated and used to predict biomimetic design parameters. Measurements of fiber diameter and pH within the microfluidic devices were collected to verify the accuracy of the computational models. Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and mechanical testing measurements were collected to characterize and compare resultant fibers. From these results, relationships were found between the incorporation of ion gradients and shear stress into the spinning process and the properties of the fibers produced.
2031-01-01
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Oliver, Eric C. J. "Spinning and mixing: Two studies of microfluidic problems using molecular dynamics simulations." Thesis, University of Ottawa (Canada), 2006. http://hdl.handle.net/10393/27400.

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Advances in microfluidics have led to the development of devices which can perform simple operations on fluids with the aim of developing a fully integrated "lab-on-a-chip". Of prime importance to this procedure is the efficient operation of each individual component. Using theoretical prediction sand two-dimensional Molecular Dynamics (MD) simulations, we have explored the operation of two such devices: one which forces a cavity of fluid into rotational motion and one to mix two different fluid species. For the rotational operation, we have referred to experimental results for a circular cavity coupled to a microfluidic channel in which a laminar flow is induced. This flow causes the fluid in the cavity to rotate which we model with MD simulations. We examine the role of wall-fluid interactions and its effect on enhancing the amount of angular momentum generated in the cavity. The reduction in wall-fluid interaction allows the fluid to slip along the wall and acquire a greater level of spin. We hope this technique can be applied experimentally to enhance the rotation in these devices. For the mixing operation, we examined a previously studied theoretical system where the authors claim obstacles in microchannels increase mixing efficiency for a fluid composed of two species. We make theoretical predictions to the contrary and demonstrate, using MD simulations, that our predictions are correct. Our results show that obstacles have two effects. First, obstacles increase the amount of contact between fluid species which only has a negligible effect on increasing the mixing efficiency. Second, the obstacles flatten the normally Poiseuille (quadratic) flow profile over a finite channel length which decreases the distance required for partial but not complete mixing. We demonstrate that all channels of at least a certain length, defined by the diffusive properties of the channel, will reach full mixing at the same point. Both projects illustrate the utility of MD simulations in predicting fluid behaviour in microfluidic systems. Our aim is that these studies can be integrated into the greater body of knowledge pertaining to microfluidics.
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Razzaq, Wasif. "Microfluidic spinning of polymer microfibers : effect of operating parameters on morphology and properties towards the development of novel and smart materials." Thesis, Strasbourg, 2022. http://www.theses.fr/2022STRAE004.

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Le filage microfluidique est une technologie émergente pour la production de micro/nanofibres qui ont un fort potentiel pour des applications telles que l’ingénierie tissulaire, l’électronique portable, les systèmes de délivrance de principes actifs et la collecte des eaux. En filage microfluidique, des fibres de diamètres et morphologies contrôlée peuvent être obtenues en manipulant précisément le débit des fluides et la géométrie du dispositif microfluidique. Le but de ce projet doctoral est de développer une expertise et des compétences dans le domaine du filage microfluidique pour produire des fibres polymères par photopolymérisation sous irradiations UV à partir de monomères en utilisant un dispositif microfluidique à base de capillaires avec les objectifs suivants : (1) la mise en place d’une relation empirique pour prédire le diamètre des fibres en prenant en compte les différents paramètres opératoires et de matériaux, (2) la production de fibres Janus/Hecate à partir de monomères ayant différentes propriétés chimiques et physiques avec un contrôle des propriétés morphologiques et mécaniques qui ont été exploitées pour adsorber simultanément des colorants chargés positivement ou négativement, mais aussi pour préparer des actuateurs à partir de fibres Janus thermorépondantes, et (3) le développement d’une approche de modification de surface des fibres pendant leur production
Microfluidic spinning is an emerging technology to produce micro/nanofibers which have a significant potential in advanced applications such as tissue engineering, wearable electronics, drug delivery, and water harvesting. In microfluidic spinning, fibers with controlled diameters and morphologies could be easily produced by precisely manipulating the fluids flow and the geometry of the microfluidic device. The purpose of this doctoral project was to develop expertise and skills in the field of microfluidic spinning to produce polymer fibers using UV photopolymerization of the monomers using a capillary-based microfluidic device with the following objectives : (1) the development of an empirical relationship to predict the fiber diameter considering the different operating and materials parameters, (2) the production of Janus/Hecate fibers from monomers with different chemical and physical properties with controllability of morphological and mechanical properties that were explored to remove simultaneously cationic and anionic dyes and to prepare thermoresponsive Janus fiber actuators, and (3) the development of an in-process rapid surface modification approach to modify the surface of fibers
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Oh, Kyung Hee. "Effect of shear, elongation and phase separation in hollow fiber membrane spinning." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53992.

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The spinning process of hollow fiber membranes was investigated with regards to two fundamental phenomena: flow (shear and elongation) and phase separation. Quantitative analysis of phase separation kinetics of binary (polymer/solvent) and ternary (polymer/solvent/volatile co-solvent) polymer solution was carried out with a newly developed microfluidic device. The device enables visualization of in situ phase separation and structure formation in controlled vapor and liquid environments. Results from these studies indicated that there was a weak correlation between phase separation kinetics and macroscopic defect (macrovoid) formation. In addition, the effect of shear and elongation on membrane morphology was tested by performing fiber extrusion through microfluidic channels. It was found that the membrane morphology is dominated by different factors depending on the rate of deformation. At high shear rates typical of spinning processes, shear was found to induce macrovoid formation through normal stresses, while elongation suppressed macroscopic defect formation. Furthermore, draw resonance, one of the key instabilities that can occur during fiber spinning, was investigated. It was found that draw resonance occurs at aggressive elongation condition, and could be suppressed by enhanced phase separation kinetics. These results can be used as guidelines for predicting hollow fiber membrane spinnability.

Частини книг з теми "Microfluidic spinning":

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Reddy, Narendra, and Yiqi Yang. "Microfluidic Spinning of Alginate Fibers." In Innovative Biofibers from Renewable Resources, 151–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-45136-6_33.

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Zhu, Pingan, and Liqiu Wang. "Microfluidic Spinning of Symmetric Microfibers." In Microfluidics-Enabled Soft Manufacture, 137–56. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-96462-7_8.

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Vasconcelos, Filipa, Rui L. Reis, Albino Martins, and Nuno M. Neves. "Biomedical Applications of Fibers Produced by Electrospinning, Microfluidic Spinning and Combinations of Both." In Electrospun Nanofibers, 251–95. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-99958-2_10.

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Тези доповідей конференцій з теми "Microfluidic spinning":

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Enomoto, Sakiko, Yuya Yajima, Yuki Watabe, Masumi Yamada, Kazuya Furusawa, and Minoru Seki. "One-step microfluidic spinning of collagen microfibers and their application to cell cultivation." In 2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS). IEEE, 2015. http://dx.doi.org/10.1109/mhs.2015.7438257.

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Saeidi, Nima, Edward Sander, and Jeffrey Ruberti. "Real Time Observation and Quantification of Shear-Induced Collagen Self-Assembly." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206773.

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Collagen is the most abundant protein in the extracellular matrix (ECM) of vertebrates and is distributed widely throughout connective tissues. Fibrillar collagen is the principal load-bearing molecule in vertebrates (e.g. type I in tendon and ligament and type II in cartilage). Its inherent biocompatibility makes collagen an attractive scaffolding material candidate for tissue engineering. Although use of 2-D or 3-D collagen networks as a substrate for cell culturing have provided invaluable information about cell-ECM interactions, it has not been very successful in producing load-bearing tissue-engineered constructs. We attribute the fundamental problem to the use of disorganized collagen which may interfere with the ability of cells to generate organization. Several research groups have developed methods to produce organized layer(s) of collagen fibrils de novo (often with the intention of using them for guiding cell culture systems). Methods employed to influence collagen fibril organization during self-assembly include, electro-spinning [1], the use of strong magnetic fields [2–4], electrical gradients [5], flows through a microfluidic channel [6, 7], a combination of fluid flow and magnetic field [8], dip-pen nanolithography [9], cholesteric methods [10], and even freezing and thawing [11]. Although there has been some progress in controlling the alignment of collagen fibrils in vitro, there are many unknown factors which govern directed collagen self-assembly.
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Hiramatsu, Hisataka, Ayaka Hori, Yuya Yajima, Masumi Yamada, and Minoru Seki. "Microfluidics-based wet spinning of protein microfibers as solid scaffolds for 3D cell cultivation." In 2016 International Symposium on Micro-NanoMechatronics and Human Science (MHS). IEEE, 2016. http://dx.doi.org/10.1109/mhs.2016.7824194.

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