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1

Park, Jungkap, Paul D. Piehowski, Christopher Wilkins, et al. "Informed-Proteomics: open-source software package for top-down proteomics." Nature Methods 14, no. 9 (2017): 909–14. http://dx.doi.org/10.1038/nmeth.4388.

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2

Korol, Elena, and Zarina Chipova. "Structural analysis of labor costs in the construction of tunnels by open, closed methods and the TOP DOWN method." Construction and Architecture 10, no. 2 (2022): 31–35. http://dx.doi.org/10.29039/2308-0191-2022-10-2-31-35.

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Анотація:
In connection with the need to increase labor productivity, the choice of effective technologies, this paragraph discusses the technology and optimization of the work schedule for the construction of transport and pedestrian tunnels. After a structural analysis of labor costs during the construction of tunnels in an open and closed way and using the TOP DOWN method (using bored piles), a technology algorithm was proposed that will systematize, optimize the construction schedule and reduce construction time by 15-20%, which will significantly increase efficiency building production.
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3

Khalid, Muhammad Farhan, Kanzal Iman, Amna Ghafoor, et al. "PERCEPTRON: an open-source GPU-accelerated proteoform identification pipeline for top-down proteomics." Nucleic Acids Research 49, W1 (2021): W510—W515. http://dx.doi.org/10.1093/nar/gkab368.

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Abstract PERCEPTRON is a next-generation freely available web-based proteoform identification and characterization platform for top-down proteomics (TDP). PERCEPTRON search pipeline brings together algorithms for (i) intact protein mass tuning, (ii) de novo sequence tags-based filtering, (iii) characterization of terminal as well as post-translational modifications, (iv) identification of truncated proteoforms, (v) in silico spectral comparison, and (vi) weight-based candidate protein scoring. High-throughput performance is achieved through the execution of optimized code via multiple threads
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4

Park, Jungkap, Paul D. Piehowski, Christopher Wilkins, et al. "Author Correction: Informed-Proteomics: open-source software package for top-down proteomics." Nature Methods 15, no. 7 (2018): 554. http://dx.doi.org/10.1038/s41592-018-0040-0.

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5

Li, Chilin, Congling Yin, Xiaoke Mu, and Joachim Maier. "Top-Down Synthesis of Open Framework Fluoride for Lithium and Sodium Batteries." Chemistry of Materials 25, no. 6 (2013): 962–69. http://dx.doi.org/10.1021/cm304127c.

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6

Sho, Kwang-Ho. "Study on the Application of Semi-open cut Top-Down Construction for Framework." Journal of the Korean Association for Spatial Structures 11, no. 2 (2011): 129–38. http://dx.doi.org/10.9712/kass.2011.11.2.129.

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7

Wang, Bing, Zhiwei Wang, Ni Pan, Jiangmei Huang, and Cuihong Wan. "Improved Identification of Small Open Reading Frames Encoded Peptides by Top-Down Proteomic Approaches and De Novo Sequencing." International Journal of Molecular Sciences 22, no. 11 (2021): 5476. http://dx.doi.org/10.3390/ijms22115476.

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Анотація:
Small open reading frames (sORFs) have translational potential to produce peptides that play essential roles in various biological processes. Nevertheless, many sORF-encoded peptides (SEPs) are still on the prediction level. Here, we construct a strategy to analyze SEPs by combining top-down and de novo sequencing to improve SEP identification and sequence coverage. With de novo sequencing, we identified 1682 peptides mapping to 2544 human sORFs, which were all first characterized in this work. Two-thirds of these new sORFs have reading frame shifts and use a non-ATG start codon. The top-down
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8

Giesel, Kristina, and Michael Kobler. "An Open Scattering Model in Polymerized Quantum Mechanics." Mathematics 10, no. 22 (2022): 4248. http://dx.doi.org/10.3390/math10224248.

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We derive a quantum master equation in the context of a polymerized open quantum mechanical system for the scattering of a Brownian particle in an ideal gas environment. The model is formulated in a top-down approach by choosing a Hamiltonian with a coupling between the system and environment that is generally associated with spatial decoherence. We extend the existing work on such models by using a non-standard representation of the canonical commutation relations, inspired by the quantization procedure applied in loop quantum gravity, which yields a model in which position operators are repl
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9

Chen, Y., G. Tebaldi, R. Roque, G. Lopp, and Y. Su. "Effects of interface condition characteristics on open-graded friction course top-down cracking performance." Road Materials and Pavement Design 13, sup1 (2012): 56–75. http://dx.doi.org/10.1080/14680629.2012.657051.

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10

Liepelt, Roman, and Marcel Brass. "Top-Down Modulation of Motor Priming by Belief About Animacy." Experimental Psychology 57, no. 3 (2010): 221–27. http://dx.doi.org/10.1027/1618-3169/a000028.

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There is recent evidence that we directly map observed actions of other agents onto our own motor repertoire, referred to as direct matching (Iacoboni et al., 1999). This was shown when we are actively engaged in joint action with others’ (Sebanz et al. 2003) and also when observing irrelevant movements while executing congruent or incongruent movements (Brass et al., 2000). However, an open question is whether direct matching in human beings is limited to the perception of intentional agents. Recent research provides contradictory evidence with respect to the question whether the direct match
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11

Baučić, M., F. Gilić, S. Bačić, and T. Duplančić-Leder. "OPEN GEOSPATIAL DATA FOR URBAN GREEN AREAS." ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences VI-4/W2-2020 (September 15, 2020): 17–24. http://dx.doi.org/10.5194/isprs-annals-vi-4-w2-2020-17-2020.

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Анотація:
Abstract. More than half of the world’s population lives in big urbanized areas. It is not rare that those areas are lacking natural green spaces. Green spaces improve different aspects of life in cities and they are becoming so important that lately more and more attention is given to the so-called green infrastructure. The first step in planning green infrastructure is acquiring information about current city greenery. In this paper, it was investigated how can airborne, spaceborne, and street-level images be used in gathering information about greenery. As spaceborne images, Sentinel-2 sate
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12

Nicolas-Vullierme, B. "A Contribution to Doubly Asymptotic Approximations: An Operator Top-Down Derivation." Journal of Vibration and Acoustics 113, no. 3 (1991): 409–15. http://dx.doi.org/10.1115/1.2930199.

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As a contribution to the theory of Doubly Asymptotic Approximations (DAAs), a formal operator top-down derivation specialized to steady-state motions is proposed for the Neumann exterior problem associated to the Helmholtz equation. It generalizes previously published ones which relied either on a modal approach [1] or on a scalar approach for a model problem [2]. The proposed derivation is based on an integral representation of the solution of the Helmholtz equation in an unbounded domain: first, two asymptotic expansions of the representation with respect to the nondimensional wave number k
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13

Sanocki, Thomas, and Jong Han Lee. "Attention-Setting and Human Mental Function." Journal of Imaging 8, no. 6 (2022): 159. http://dx.doi.org/10.3390/jimaging8060159.

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This article provides an introduction to experimental research on top-down human attention in complex scenes, written for cognitive scientists in general. We emphasize the major effects of goals and intention on mental function, measured with behavioral experiments. We describe top-down attention as an open category of mental actions that initiates particular task sets, which are assembled from a wide range of mental processes. We call this attention-setting. Experiments on visual search, task switching, and temporal attention are described and extended to the important human time scale of sec
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14

Chen, Wei, and Da Deng. "Sodium-cutting: a new top-down approach to cut open nanostructures on nonplanar surfaces on a large scale." Chem. Commun. 50, no. 87 (2014): 13327–30. http://dx.doi.org/10.1039/c4cc02409e.

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15

Pershing, Andrew J., Katherine E. Mills, Nicholas R. Record, et al. "Evaluating trophic cascades as drivers of regime shifts in different ocean ecosystems." Philosophical Transactions of the Royal Society B: Biological Sciences 370, no. 1659 (2015): 20130265. http://dx.doi.org/10.1098/rstb.2013.0265.

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Анотація:
In ecosystems that are strongly structured by predation, reducing top predator abundance can alter several lower trophic levels—a process known as a trophic cascade. A persistent trophic cascade also fits the definition of a regime shift. Such ‘trophic cascade regime shifts' have been reported in a few pelagic marine systems—notably the Black Sea, Baltic Sea and eastern Scotian Shelf—raising the question of how common this phenomenon is in the marine environment. We provide a general methodology for distinguishing top-down and bottom-up effects and apply this methodology to time series from th
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16

Despland, Emma, and Paola G. Santacruz. "Top-down and bottom-up controls on an herbivore on a native and introduced plant in a tropical agricultural landscape." PeerJ 8 (March 13, 2020): e8782. http://dx.doi.org/10.7717/peerj.8782.

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The recent introduction in a tropical agricultural environment of a weedy open-habitat plant (Solanum myriacanthum) and subsequent host range expansion of a common forest-edge butterfly (Mechanitis menapis) onto that plant provides an opportunity to examine reconfiguration of tritrophic networks in human-impacted landscapes. The objectives of this study were (1) determine if the caterpillars on the exotic host are more or less limited by plant defenses (bottom-up forces) and if they experience enemy release (decrease of top-down pressure) and (2) define how anthropic open pasture habitat influ
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17

Gu, Yuhang, Jie Hao, Bing Chen, and Hai Deng. "Top-Down Pyramid Fusion Network for High-Resolution Remote Sensing Semantic Segmentation." Remote Sensing 13, no. 20 (2021): 4159. http://dx.doi.org/10.3390/rs13204159.

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In recent years, high-resolution remote sensing semantic segmentation based on data fusion has gradually become a research focus in the field of land classification, which is an indispensable task of a smart city. However, the existing feature fusion methods with bottom-up structures can achieve limited fusion results. Alternatively, various auxiliary fusion modules significantly increase the complexity of the models and make the training process intolerably expensive. In this paper, we propose a new lightweight model called top-down pyramid fusion network (TdPFNet) including a multi-source fe
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18

Liin, Sara I., Per-Eric Lund, Johan E. Larsson, Johan Brask, Björn Wallner, and Fredrik Elinder. "Biaryl sulfonamide motifs up- or down-regulate ion channel activity by activating voltage sensors." Journal of General Physiology 150, no. 8 (2018): 1215–30. http://dx.doi.org/10.1085/jgp.201711942.

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Voltage-gated ion channels are key molecules for the generation of cellular electrical excitability. Many pharmaceutical drugs target these channels by blocking their ion-conducting pore, but in many cases, channel-opening compounds would be more beneficial. Here, to search for new channel-opening compounds, we screen 18,000 compounds with high-throughput patch-clamp technology and find several potassium-channel openers that share a distinct biaryl-sulfonamide motif. Our data suggest that the negatively charged variants of these compounds bind to the top of the voltage-sensor domain, between t
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19

McCluney, Kevin E., and John L. Sabo. "Animal water balance drives top-down effects in a riparian forest—implications for terrestrial trophic cascades." Proceedings of the Royal Society B: Biological Sciences 283, no. 1836 (2016): 20160881. http://dx.doi.org/10.1098/rspb.2016.0881.

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Despite the clear importance of water balance to the evolution of terrestrial life, much remains unknown about the effects of animal water balance on food webs. Based on recent research suggesting animal water imbalance can increase trophic interaction strengths in cages, we hypothesized that water availability could drive top-down effects in open environments, influencing the occurrence of trophic cascades. We manipulated large spider abundance and water availability in 20 × 20 m open-air plots in a streamside forest in Arizona, USA, and measured changes in cricket and small spider abundance
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20

Moree, Dana. "Travelling Educational Change and Cultural Diversity in the Czech Republic." Lifelong Learning 3, no. 1 (2013): 51–72. http://dx.doi.org/10.11118/lifele2013030151.

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This article analyses the interconnectedness of travelling policy and domestic top-down and bottom-up processes in the case of a country going through a transformation from a communist to a more open system. This interconnectedness and the dilemmas it poses will be examined in several steps. After a theoretical introduction to the concept of travelling policy and domestic bottom-up and top-down processes, we will introduce the initial situation of the educational system in the Czech Republic around 1989. We will then analyse the process of educational change, and we will describe how Czech tea
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21

Resende, David Nunes, and Marco Bravo. "A TOP-DOWN AND BOTTOM-UP APPROACH TO IMPROVE REGIONAL INNOVATION ECOSYSTEMS IN PORTUGAL." Brazilian Journal of Operations & Production Management 13, no. 1 (2016): 86. http://dx.doi.org/10.14488/bjopm.2016.v13.n1.a10.

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The objective of this article is to present a successful program that built a National Innovation Network based in the University Technology Transfer Offices (TTOs), incubators and science parks.The University Technology Enterprise Network (UTEN), which was launched in March 2007, includes 15 Portuguese Universities and select international partners in a 5-Year program funded by the Portuguese government. The main objective has been to accelerate the development of a sustainable, globally competitive, professional technology transfer and commercialization network within Portugal to increase Po
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22

Alkahtani, Aishah. "Curriculum change management and workload." Improving Schools 20, no. 3 (2017): 209–21. http://dx.doi.org/10.1177/1365480217706789.

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This study examines the ways in which Saudi teachers have responded or are responding to the challenges posed by a new curriculum. It also deals with issues relating to workload demands which affect teachers’ performance when they apply a new curriculum in a Saudi Arabian secondary school. In addition, problems such as scheduling and sharing space require committee negotiations between head teachers, teachers, and higher level management in the project. The results show the importance of open communication, and a bottom-up as well as a top-down flow of decision-making. Communication and decisi
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23

Rosyada, Amron, R. Dimas Endro W, and M. Arif Kurniawan. "Effects of adding sideboard and longitudinal bulkhead construction on ship stability of open-top cargo ship." IOP Conference Series: Earth and Environmental Science 1166, no. 1 (2023): 012042. http://dx.doi.org/10.1088/1755-1315/1166/1/012042.

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Abstract The cargo cover removal on cargo ship will surely affect the technical condition of ship accomplishment that is regulated by rule. In this study, the author would like to evaluate the down-flooding point and free surface effect on open-top cargo ship to the stability acceptance criteria using IMO and DNV test procedures. The simulation result shows that the ship stability value is not in the range of the value required with IMO A.749(18) stability criteria. The failures are caused by lower down-flooding point and free surface effect. The Construction modifications effect by adding sid
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24

Li, Chenning, and Zhichao Cao. "LoRa Networking Techniques for Large-scale and Long-term IoT: A Down-to-top Survey." ACM Computing Surveys 55, no. 3 (2023): 1–36. http://dx.doi.org/10.1145/3494673.

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Анотація:
Low-Power Wide-Area Networks (LPWANs) are an emerging Internet-of-Things (IoT) paradigm, which caters to large-scale and long-term sensory data collection demand. Among the commercialized LPWAN technologies, LoRa (Long Range) attracts much interest from academia and industry due to its open-source physical (PHY) layer and standardized networking stack. In the flourishing LoRa community, many observations and countermeasures have been proposed to understand and improve the performance of LoRa networking in practice. From the perspective of the LoRa networking stack; however, we lack a whole pic
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25

Yun, Jinhyo Joseph, Xiaofei Zhao, KyungBae Park, and Lei Shi. "Sustainability Condition of Open Innovation: Dynamic Growth of Alibaba from SME to Large Enterprise." Sustainability 12, no. 11 (2020): 4379. http://dx.doi.org/10.3390/su12114379.

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Анотація:
Research Question: Open innovation and the open business model exaggerate complexity (a transaction cost) in addition to the realization of emergence and its lock-in. Within a short period, Alibaba has become one of the global top e-commerce companies with several open innovation business models. Our research question was: “How could Alibaba become a global top e-commerce company in China in such a short time?” Research Method: We chose a deep interview method, participatory observation, and meta-analysis to answer this research question. Research Result: Alibaba has applied global, creative e
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26

Macaluso, Emiliano, Uta Noppeney, Durk Talsma, Tiziana Vercillo, Jess Hartcher-O’Brien, and Ruth Adam. "The Curious Incident of Attention in Multisensory Integration: Bottom-up vs. Top-down." Multisensory Research 29, no. 6-7 (2016): 557–83. http://dx.doi.org/10.1163/22134808-00002528.

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The role attention plays in our experience of a coherent, multisensory world is still controversial. On the one hand, a subset of inputs may be selected for detailed processing and multisensory integration in a top-down manner, i.e., guidance of multisensory integration by attention. On the other hand, stimuli may be integrated in a bottom-up fashion according to low-level properties such as spatial coincidence, thereby capturing attention. Moreover, attention itself is multifaceted and can be describedviaboth top-down and bottom-up mechanisms. Thus, the interaction between attention and multi
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27

SMITH, WALKER O., and CHRISTIANE LANCELOT. "Bottom-up versus top-down control in phytoplankton of the Southern Ocean." Antarctic Science 16, no. 4 (2004): 531–39. http://dx.doi.org/10.1017/s0954102004002305.

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Oceanic phytoplankton communities are a mixture of various algal functional groups, all of which are of different sizes, have variable physiologies, and interact differently with disparate herbivores. We suggest that polar plankton communities, and specifically the larger phytoplankton of Southern Ocean HNLC (high nutrient, low chlorophyll) systems, are controlled primarily by bottom-up processes, but that smaller (pico- and nanoplankton) reach an equilibrium that is set simultaneously by light, iron and grazing by microzooplankton. Thus Southern Ocean phytoplankton conforms to the “ecumenical
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28

Kučera, Jan, and Dušan Chlapek. "Comparison of Approaches to Publication of Open Government Data in Two Czech Public Sector Bodies." JeDEM - eJournal of eDemocracy and Open Government 6, no. 1 (2014): 106–11. http://dx.doi.org/10.29379/jedem.v6i1.316.

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This case study compares approaches to publication of Open Government Data in two Czech public sector bodies: the Czech Telecommunication Office (CTO) and the Czech Trade Inspection Authority (CTIA). The top-down approach applied by the CTO is compared to the bottom-up approach applied by the CTIA. Results achieved by these two public sector bodies are described and the case study is concluded with the lessons learned.
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29

Meilyanawindaperdana, Rama Kipran, and Aminullah Imal Alfresi. "Implementasi Cisco Packet Tracer pada Infrastruktur Jaringan Komputer di PT Pertamina Hulu Rokan Prabumulih Field." Jurnal CoSciTech (Computer Science and Information Technology) 3, no. 2 (2022): 138–43. http://dx.doi.org/10.37859/coscitech.v3i2.3946.

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Jaringan Local Area Network suatu jaringan komputer yang menyambungkan komputer dalam suatu area terbatas Mobile User Tujuan Dari Penelitian ini yaitu untuk melakukan aktivitas kerja dalam pengelolaan data, menggunakan share folder yang bisa diakses dengan VPN untuk membuka data maupun mencari informasi penting lainnya. Sehingga Implemtasi Infrastruktur jaringan Komputer sangat penting guna menunjang kinerja di PT Pertamina. Metode digunakan dalam penelitian ini adalah Top DownTop Down merupakan metode untuk merancang jaringan yang dimulai pada lapisan atas model referensi Open System Iterconn
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30

Stojanovski, Jadranka. "Open Access Infrastructure for Research in Croatia." Digital Presentation and Preservation of Cultural and Scientific Heritage 5 (September 30, 2015): 79–88. http://dx.doi.org/10.55630/dipp.2015.5.7.

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Анотація:
There is a vibrant Open Access environment in Croatia and several academic and research institutions initiate different activities concerning open access to the scientific information (Ru đer Boš kovi ć Institute, School of Medicine, Faculty of Humanities and Social Sciences, Faculty of Mechanical Engineering and Naval Architecture, Faculty of Organization and Informatics at University of Zagreb, University of Zadar, University of Osijek, National and University Library, etc.). It is very important to improve collaboration among different stakeholders, as well as to provide top-down guidance h
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31

Capdevila, Ignasi, and Matías I. Zarlenga. "Smart city or smart citizens? The Barcelona case." Journal of Strategy and Management 8, no. 3 (2015): 266–82. http://dx.doi.org/10.1108/jsma-03-2015-0030.

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Анотація:
Purpose – In recent years, the term “smart city” has attracted a lot of attention from policy makers, business leaders and citizenship in general. Although there is not a unique definition of what a smart city is, it is generally accepted that “smart” urban policies refer to local governments’ initiatives that use information and communication technologies in order to increase the quality of life of their inhabitants while contributing to a sustainable development. So far, “smart city” approaches have generally been related to top-down processes of technology diffusion. The purpose of this pap
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32

Ichoku, C., and L. Ellison. "Global top-down smoke aerosol emissions estimation using satellite fire radiative power measurements." Atmospheric Chemistry and Physics Discussions 13, no. 10 (2013): 27327–86. http://dx.doi.org/10.5194/acpd-13-27327-2013.

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Abstract. Biomass burning occurs seasonally in most vegetated parts of the world, consuming large amounts of biomass fuel, generating intense heat energy, and emitting corresponding amounts of smoke plumes that comprise different species of aerosols and trace gases. Accurate estimates of these emissions are required as model inputs to evaluate and forecast smoke plume transport and impacts on air quality, human health, clouds, weather, radiation, and climate. Emissions estimates have long been based on bottom-up approaches that are not only complex, but also fraught with compounding uncertaint
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33

Marslen-Wilson, William D. "What phonetic decision making does not tell us about lexical architecture." Behavioral and Brain Sciences 23, no. 3 (2000): 337–38. http://dx.doi.org/10.1017/s0140525x00353249.

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Анотація:
Norris et al. argue against using evidence from phonetic decision making to support top-down feedback in lexical access on the grounds that phonetic decision relies on processes outside the normal access sequence. This leaves open the possibility that bottom-up connectionist models, with some contextual constraints built into the access process, are still preferred models of spoken-word recognition.
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34

Beeker, Timo, Anna Witeska-Młynarczyk, Sanne te Meerman, and China Mills. "Psychiatrization of, with and by children: Drawing a complex picture." Global Studies of Childhood 10, no. 1 (2020): 12–25. http://dx.doi.org/10.1177/2043610619890074.

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When discussed in the context of diagnosing or medicating children, psychiatrization is usually portrayed as a more or less monolithic top-down process, which, according to some, enables a child’s right to health, while for others is a form of child abuse. This article challenges these conceptualizations in two steps: First, it draws on available literature on psychiatrization (including its top-down and bottom-up operations, and its ideological and material aspects), and its relationship to various psy-practices, and wider processes of (bio) medicalization, psychologization and reification. S
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35

Kimbro, David L., J. Wilson White, and Edwin D. Grosholz. "The dynamics of open populations: integration of top–down, bottom–up and supply–side influences on intertidal oysters." Oikos 128, no. 4 (2018): 584–95. http://dx.doi.org/10.1111/oik.05892.

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36

Su, Taojunfeng, Michael A. R. Hollas, Ryan T. Fellers, and Neil L. Kelleher. "Identification of Splice Variants and Isoforms in Transcriptomics and Proteomics." Annual Review of Biomedical Data Science 6, no. 1 (2023): 357–76. http://dx.doi.org/10.1146/annurev-biodatasci-020722-044021.

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Alternative splicing is pivotal to the regulation of gene expression and protein diversity in eukaryotic cells. The detection of alternative splicing events requires specific omics technologies. Although short-read RNA sequencing has successfully supported a plethora of investigations on alternative splicing, the emerging technologies of long-read RNA sequencing and top-down mass spectrometry open new opportunities to identify alternative splicing and protein isoforms with less ambiguity. Here, we summarize improvements in short-read RNA sequencing for alternative splicing analysis, including
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37

Fricke, Ute, Ingolf Steffan-Dewenter, Jie Zhang, et al. "Landscape diversity and local temperature, but not climate, affect arthropod predation among habitat types." PLOS ONE 17, no. 4 (2022): e0264881. http://dx.doi.org/10.1371/journal.pone.0264881.

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Arthropod predators are important for ecosystem functioning by providing top-down regulation of insect herbivores. As predator communities and activity are influenced by biotic and abiotic factors on different spatial scales, the strength of top-down regulation (‘arthropod predation’) is also likely to vary. Understanding the combined effects of potential drivers on arthropod predation is urgently needed with regard to anthropogenic climate and land-use change. In a large-scale study, we recorded arthropod predation rates using artificial caterpillars on 113 plots of open herbaceous vegetation
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38

Wang, Hui. "Designing the everyday." Architectural Research Quarterly 21, no. 3 (2017): 208–21. http://dx.doi.org/10.1017/s1359135517000501.

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Анотація:
In China, although the ‘everyday’ should be studied as one of the most fundamental architectural issues, it is frequently neglected by Chinese architects. A consciousness for the ‘everyday’ is marginalised by the prevailing ‘non-everyday’ backed by a top-down way of reasoning. Under this circumstance, it is constructive to reconsider the ‘everyday’ in order to open up new potentials for the design practice and discourse in architecture.
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39

Maneth, Sebastian. "A Survey on Decidable Equivalence Problems for Tree Transducers." International Journal of Foundations of Computer Science 26, no. 08 (2015): 1069–100. http://dx.doi.org/10.1142/s0129054115400134.

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The decidability of equivalence for three important classes of tree transducers is discussed. Each class can be obtained as a natural restriction of deterministic macro tree transducers (MTTs): (1) no context parameters, i.e., top-down tree transducers, (2) linear size increase, i.e., MSO definable tree transducers, and (3) monadic input and output ranked alphabets. For the full class of mtts, decidability of equivalence remains a long-standing open problem.
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40

Masoumi, Hadi, Bahar Farahani, and Fereidoon Shams Aliee. "Systematic and ontology-based approach to interoperable cross-domain open government data services." Transforming Government: People, Process and Policy 16, no. 1 (2021): 110–27. http://dx.doi.org/10.1108/tg-08-2021-0132.

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Purpose Open government data (OGD) has emerged as a radical paradigm shift and endeavor among government administrations across the world mainly due to its promises of transparency, accountability, public-private collaboration, civic participation, social innovation and data-driven value creation. Complexity, cross-cutting nature, diversity of data sets, interoperability and quality issues usually hamper unlocking the full potential value of data. To tackle these challenges, this paper aims to provide a novel solution using a top-down approach. Design/methodology/approach In this paper, the au
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41

Lesne, Jean, Marie-Pierre Bousquet, Julien Marcoux, and Marie Locard-Paulet. "Top-Down and Intact Protein Mass Spectrometry Data Visualization for Proteoform Analysis Using VisioProt-MS." Bioinformatics and Biology Insights 13 (January 2019): 117793221986822. http://dx.doi.org/10.1177/1177932219868223.

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The rise of intact protein analysis by mass spectrometry (MS) was accompanied by an increasing need for flexible tools allowing data visualization and analysis. These include inspection of the deconvoluted molecular weights of the proteoforms eluted alongside liquid chromatography (LC) through their representation in three-dimensional (3D) liquid chromatography coupled to mass spectrometry (LC-MS) maps (plots of deconvoluted molecular weights, retention times, and intensity of the MS signal). With this aim, we developed a free and open-source web application named VisioProt-MS ( https://massto
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42

Alcalá-Alcalá, Sergio, José Eduardo Casarrubias-Anacleto, Maximiliano Mondragón-Guillén, et al. "Melanin Nanoparticles Obtained from Preformed Recombinant Melanin by Bottom-Up and Top-Down Approaches." Polymers 15, no. 10 (2023): 2381. http://dx.doi.org/10.3390/polym15102381.

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Melanin is an insoluble, amorphous polymer that forms planar sheets that aggregate naturally to create colloidal particles with several biological functions. Based on this, here, a preformed recombinant melanin (PRM) was utilized as the polymeric raw material to generate recombinant melanin nanoparticles (RMNPs). These nanoparticles were prepared using bottom-up (nanocrystallization—NC, and double emulsion–solvent evaporation—DE) and top-down (high-pressure homogenization—HP) manufacturing approaches. The particle size, Z-potential, identity, stability, morphology, and solid-state properties w
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43

YSTRÖM, ANNA, and HEDVIG ASPENBERG. "OPEN FOR INNOVATION? PRACTICES SUPPORTING COLLABORATION IN SWEDISH REGIONAL CLUSTERS." International Journal of Innovation Management 21, no. 05 (2017): 1740008. http://dx.doi.org/10.1142/s1363919617400084.

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While it could be argued that globalisation would diminish the importance of a company’s location, research has shown that in an increasingly complex, knowledge-based and dynamic economy, regional collaboration has in fact become a critical aspect of enhancing competitiveness, locally as well as globally. Still, in order to create sustainable, innovative and successful clusters, interaction and collaboration among its members is necessary, which is not always easy to accomplish and requires actions that stimulate bottom-up activity rather than top-down directives. Taking a practice-based persp
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44

Granell, C., D. Bhattacharya, S. Casteleyn, et al. "GEO-C: ENABLING OPEN CITIES AND THE OPEN CITY TOOLKIT." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-4/W8 (July 11, 2018): 61–68. http://dx.doi.org/10.5194/isprs-archives-xlii-4-w8-61-2018.

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<p><strong>Abstract.</strong> The GEO-C doctoral programme, entitled “Geoinformatics: Enabling Open Cities”, is funded by the EU Marie Skłodowska-Curie actions (International Training Networks (ITN), European Joint Doctorates) until December 2018, and is managed by three European universities in Germany, Portugal and Spain. 15 doctoral grantholders (Early Stage Researchers) were selected to work on specific three-year projects, all contributing to improving the notion of open cities, and specifically to an Open City Toolkit of methodologies, code, and best practice examples.
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45

Xue, Yang, Hanzhi Yu, and Geng Qin. "Towards Good Governance on Dual-Use Biotechnology for Global Sustainable Development." Sustainability 13, no. 24 (2021): 14056. http://dx.doi.org/10.3390/su132414056.

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Dual-use biotechnology faces the risks of availability, novel biological agents, knowledge, normative, and other dual-use risks. If left unchecked, these may destroy human living conditions and social order. Despite the benefits of dual-use technology, good governance is needed to mitigate its risks. The predicaments facing all governments in managing the dual-use risks of biotechnology deserve special attention. On the one hand, the information asymmetry risk of dual-use biotechnology prevents the traditional self-governance model in the field of biotechnology from playing its role. On the ot
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46

Riedl, Valentin, Lukas Utz, Gabriel Castrillón, et al. "Metabolic connectivity mapping reveals effective connectivity in the resting human brain." Proceedings of the National Academy of Sciences 113, no. 2 (2015): 428–33. http://dx.doi.org/10.1073/pnas.1513752113.

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Directionality of signaling among brain regions provides essential information about human cognition and disease states. Assessing such effective connectivity (EC) across brain states using functional magnetic resonance imaging (fMRI) alone has proven difficult, however. We propose a novel measure of EC, termed metabolic connectivity mapping (MCM), that integrates undirected functional connectivity (FC) with local energy metabolism from fMRI and positron emission tomography (PET) data acquired simultaneously. This method is based on the concept that most energy required for neuronal communicat
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47

Yulihasri, Dr, Arief Prima Johan, Rebi Fara Handika, and Dr Herri. "A QUALITATIVE INVESTIGATION ON THE SUCCESSFUL TURNAROUND STRATEGY FROM TOP LEADER PERSPECTIVES: EXAMPLES FROM INDONESIA." Business: Theory and Practice 19 (June 20, 2018): 114–22. http://dx.doi.org/10.3846/btp.2018.12.

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Turnaround process involved many approaches of strategic and tactical attempts. However, such knowledge are difficult to identified since many previous studies only focused on what constitute successful turnaround, and limited to the use of financial data. As turnaround is a transformational process comprehend every element of organization, ploy on implementing and orchestrating such strategic action should be determined by company’s top leaders. The purpose of this study was to explore the way in which leaders manage the company’s turnaround process and their leadership style through a qualit
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48

Antoniou, J., and G. Bergeles. "Development of the Reattached Flow Behind Surface-Mounted Two-Dimensional Prisms." Journal of Fluids Engineering 110, no. 2 (1988): 127–33. http://dx.doi.org/10.1115/1.3243524.

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Velocity and turbulence measurements are presented for the region after reattachment behind a two dimensional surface-mounted prism of varying length. The prism is mounted on the floor of an open circuit blow down wind tunnel and flow parameters for the developing boundary layer are deduced from the measurements; longitudinal integral time and length scales are estimated through autocorrelations. Reattchment on top of the prism, due to its increased length, affects the characteristics of the developing boundary layer; in this case the shear layer originating from the up-stream edge of the pris
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49

Li, Xin, Torben Juul Andersen, and Carina Antonia Hallin. "A Zhong-Yong perspective on balancing the top-down and bottom-up processes in strategy-making." Cross Cultural & Strategic Management 26, no. 3 (2019): 313–36. http://dx.doi.org/10.1108/ccsm-01-2019-0018.

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Анотація:
Purpose The purpose of this paper is to propose an alternative perspective on Zhong-Yong that is different from the notion of “Yin-Yang balancing” and apply it to understand the issue of balancing the top-down and bottom-up processes in strategy making. Design/methodology/approach The authors adopt a “West meets East” mindset and approach to develop an alternative perspective on Zhong-Yong, and then apply this perspective to understand the issue of balancing the top-down and bottom-up processes in strategy making. There are three steps in the process of developing the alternative perspective.
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50

Zhilina, Larisa Vladimirovna. "Japanese Universities’ Community in International Environment: Maneuvers or Heading Down?" Vestnik RUDN. International Relations 19, no. 1 (2019): 119–29. http://dx.doi.org/10.22363/2313-0660-2019-19-1-119-129.

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The article discusses the issues that striving for getting on the first lines of ratings, Japanese universities have faced to face with in recent years. Since 2003, when universities began to receive their public evaluation on the pages of global university ratings, the world university system has entered a new phase of its development. For many countries, including Japan, getting into the top-list of global ratings has become almost a national goal. Of the new issues that have emerged over the course of the past years, the most important at present is the “internationalization” of Japanese un
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