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Готові списки джерел за темами / Pharmacological Investigations

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Добірка наукової літератури з теми "Pharmacological Investigations"

Автор: Grafiati

Опубліковано: 7 червня 2025

Оновлено: 2 серпня 2025

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Статті в журналах з теми "Pharmacological Investigations"

1

RENUKA, JAIN, and ARORA REKHA. "Phytochemical and Pharmacological Investigation of Heliotropium ellipticum Ledeb." Journal of Indian Chemical Society Vol. 74, May 1997 (1997): 430–31. https://doi.org/10.5281/zenodo.5909098.

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Department of Chemistry, University of Rajasthan. Jaipur-302 004 <em>Manuscript received 31 October 1995. revised 18 January 1996, accepted 19 January 1996</em> Phytochemical and Pharmacological Investigation of <em>Heliotropium ellipticum</em> Ledeb.

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2

Zinovieva, M. L., N. V. Kurdil, P. G. Zhminko, M. G. Prodanchuk, O. P. Kravchuk, and M. V. Velychko. "Pharmacological therapeutic appliance for acute poisoning by organophosphorous compounds of anticholinesterase action (review of literature)." Ukrainian Journal of Modern Toxicological Aspects 94, no. 1 (2023): 42–54. http://dx.doi.org/10.33273/2663-4570-2023-94-1-42-54.

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The current standards of treatment the acute OPC poisoning with anticholinesterase action remain insufficient, despite the significant number of researches in this area conducted in the world. One of the ways to solve this problem is to use a wider range of pathogenetically determined pharmacologic agents. The Aim of the Research. To observe and summarize the published results of investigation the pharmacological therapeutic appliance for acute OPC poisoning at the stages of preclinical and early clinical evaluation. Methods. System content analysis of literature data using the PubMed and Goog

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3

Kuhnt, M., A. Pröbstle, R. Bauer, and M. Heinrich. "Biological and Pharmacological Investigations ofHyptis verticillata." Planta Medica 59, S 1 (1993): A665. http://dx.doi.org/10.1055/s-2006-959935.

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4

Bauer, R., K. Redl, and B. Davis. "Phytochemical and Pharmacological Investigations ofBidens campylotheca." Planta Medica 57, S 2 (1991): A68. http://dx.doi.org/10.1055/s-2006-960333.

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5

Sendl, A., G. Elbl, B. Steinke, K. Redl, W. Breu, and H. Wagner. "Comparative Pharmacological Investigations ofAllium ursinumandAllium sativum." Planta Medica 58, no. 01 (1992): 1–7. http://dx.doi.org/10.1055/s-2006-961378.

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6

Varpe, Bhushan D. "Isatin Hybrids and Their Pharmacological Investigations." Mini-Reviews in Medicinal Chemistry 21, no. 10 (2021): 1182–225. http://dx.doi.org/10.2174/18755607mteydmjykw.

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Nourmohammadi, Jalal, Mohsen Akhondi, Fereshte Rajabiniat, Zahra S. H. Vaeaz, Zahra Nourmohammadi, and Mahdieh H. Moghadam. "Pharmacological evaluation of glomerulonephritis in Covid-19 patients." Romanian Journal of Military Medicine 125, no. 4 (2022): 630–35. http://dx.doi.org/10.55453/rjmm.2022.125.4.14.

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"Acute kidney injury (AKI) and glomerulonephritis can be complications in COVID-19 patients, which is announced with widely incidence rates in different investigations and is determined to have a major effect on the prognosis of the disease. There are considerable variations in AKI and glomerulonephritis rates between other countries. The rate is generally lower than in Western Europe and the United States in China. Heterogeneity in different racial and ethnic lines can be a potential explanation. This investigation systematically reviews the scientific resources regarding AKI and glomerulonep

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8

Kosic-Spasojevic, Ljubica, and Dragisa Trailovic. "Possibilities of applying pharmacological stress testing in assessment of heart functional capacity in dogs." Veterinarski glasnik 64, no. 3-4 (2010): 287–96. http://dx.doi.org/10.2298/vetgl1004287k.

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Systolic and diastolic heart functions, evaluated using echocardiography, do not reflect the functional capacity of the patient and they cannot explain the occurrence of symptoms during a certain degree of activity. Evaluation of the functional capacity is an integral part of cardiological examinations in human medicine. Functional examinations of the heart can be carried out using the body burden test or pharmacologically. Investigations carried out so far into canine cardiology have not contributed to the clinical implementation of functional heart examinations in dogs. Pharmacological stres

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9

Zhou, Zehua, Rui An, Lisha You, Kun Liang, and Xinhong Wang. "Banxia Xiexin decoction: A review on phytochemical, pharmacological, clinical and pharmacokinetic investigations." Medicine 102, no. 35 (2023): e34891. http://dx.doi.org/10.1097/md.0000000000034891.

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Banxia Xiexin decoction (BXD), a famous traditional Chinese prescription constituted by Pinelliae Rhizoma, Zingiberis Rhizoma, Scutellariae Radix, Coptidis Rhizoma, Ginseng Radix et Rhizoma, Jujubae Fructus and Glycyrrhizae Radix et Rhizoma Praeparata Cum Mell, has notable characteristics of acrid-opening, bitter down-bearing and sweet-tonification, interfering with tumors, gastrointestinal diseases, central nervous system diseases and much more. Based on the wide clinical applications, current investigations of BXD focused on several aspects: chemical analysis to explore the underlying substr

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Little, H. J., A. Clark, and W. P. Watson. "Investigations into pharmacological antagonism of general anaesthesia." British Journal of Pharmacology 129, no. 8 (2000): 1755–63. http://dx.doi.org/10.1038/sj.bjp.0703262.

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Дисертації з теми "Pharmacological Investigations"

1

Pamplin, P. J. "Physiological and pharmacological investigations into trigeminal pain." Thesis, University of Bristol, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381413.

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2

Sand, Carsten. "Pharmacological investigations on reactive oxygen species in the cardiovascular system." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2002. http://dare.uva.nl/document/64883.

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3

Robertson, Stuart. "The bovine perfused eye as a model for pharmacological investigations." Thesis, University of Glasgow, 1999. http://theses.gla.ac.uk/39027/.

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The isolated perfused eye of many species has become a frequently used model in the study of ocular pharmacology. Due to its availability, cheapness and comfortable size for experimental use the bovine eye provides an attractive model for conducting perfusion experiments. Although initially rejected by Kishida et al. (1985), the bovine perfused eye has been proved to be a valid model for studying aqueous humour dynamics and the pharmacology of various antiglaucoma drugs, including the β-adrenoceptor antagonist, timolol, and the carbonic anhydrase inhibitor, MK-927 (Wilson et al., 1993). A gene

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4

Youssef, Ahmed Mohamed Mohamed. "Pharmacological investigations into matrix metalloproteinase-activated anti-tumour prodrugs : in vitro metabolic and pharmacological investigations into a series of colchicine-based peptide prodrugs activated by tumour-expressed matrix metalloproteinases." Thesis, University of Bradford, 2014. http://hdl.handle.net/10454/13982.

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Matrix metalloproteinases (MMPs) play a significant role in degrading the extracellular matrix in cancer development and metastasis. Overexpression of matrix metalloproteinases in tumour tissues relative to normal tissues has been exploited as a target for peptide-based therapeutics, to improve therapeutic index of currently used agents. The stability of MMP-activated prodrugs in normal tissue or organs is a significant challenge for their success in the clinic. In an in vitro study, the stability of twenty six prodrugs was studied in mouse liver, kidney, lung and tumour homogenates using HPLC

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Youssef, Ahmed M. M. "Pharmacological investigations into matrix metalloproteinase-activated anti-tumour prodrugs. In vitro metabolic and pharmacological investigations into a series of colchicine-based peptide prodrugs activated by tumour-expressed matrix metalloproteinases." Thesis, University of Bradford, 2014. http://hdl.handle.net/10454/13982.

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Carmen, Kimberly A. del. "Pharmacological and molecular investigations of mechanisms of metamorphosis in the marine gastropod Phestilla sibogae." Thesis, University of Hawaii at Manoa, 2003. http://hdl.handle.net/10125/3052.

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Metamorphosis is the critical link between the larval and adult forms in the biphasic life cycle of many diverse metazoans. Metamorphosis in the marine gastropod Phestilla sibogae is rapid (taking less than 24 hours) and results in a change in habitat and feeding mode from larval facultative planktotrophs to benthic, carnivorous adults feeding on the coral P. compressa. During metamorphosis larvae of P. sibogae lose several structures such as the larval shell and operculum, the velum, larval kidney cells, larval retractor muscles, nephrocysts, and foot glands. In addition, morphogenic changes

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Sawant, Meera. "In Vitro Investigations of Antibiotic Influences on Nerve Cell Network Responses to Pharmacological Agents." Thesis, University of North Texas, 2014. https://digital.library.unt.edu/ark:/67531/metadc699991/.

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Neuronal networks, derived from mouse embryonic frontal cortex (FC) tissue grown on microelectrode arrays, were used to investigate effects of gentamicin pretreatment on pharmacological response to the L-type calcium channel blocker, verapamil. Gentamicin is a broad spectrum antibiotic used to control bacterial contamination in cell culture. The addition of gentamicin directly to medium affects the pharmacological and morphological properties of the cells in culture. A reproducible dose response curve to verapamil from untreated cultures was established and the mean EC50 was calculated to be 1

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Hald, Andreas. "Pharmacological testing and investigations of spinal astrogliosis in a murine bone cancer pain model /." Cph. : Copenhagen University, Faculty of Pharmaceutical Sciences, Department of Pharmacology and Pharmacotherapy, 2007. http://www.farma.ku.dk/index.php/Andreas-Hald/4975/0/.

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Chan, Susan L. F. "Biochemical and pharmacological investigations into the role of α2-adrenoceptors in rat islets of Langerhans". Thesis, Keele University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292754.

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Kellermann, Tracy. "A Pharmacological investigations of South Africa Lichens, Dessication-tolerant Plants and Medicinal Tree, Warburgia Salutaris." Doctoral thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/3284.

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Книги з теми "Pharmacological Investigations"

1

Rauf, Abdur, Hafiz Ansar Rasul Suleria, and Syed Muhammad Mukarram Shah. Phytochemical and Pharmacological Investigation of the Family Rutaceae. Apple Academic Press, 2024. http://dx.doi.org/10.1201/9781003401469.

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2

Nichols, Eve K. Expanding access to investigational therapies for HIV infection and AIDS: March 12-13, 1990, conference summary. National Academy Press, 1991.

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3

Dash, Pritesh Ranjan. Phytochemical Screening and Pharmacological Investigations on Hedychium Coronarium. Anchor Academic Publishing. ein Imprint der Diplomica Verlag GmbH, 2016.

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4

Chowdhury, Aszadur Rahman, K. M. Shams-Ud-Doha, and Kh Tanvir Ahmed. Phytochemical and Biological Investigations of Thunbergia grandiflora: Characterization of phytochemical compounds and pharmacological activities of Thunbergia grandiflora. LAP LAMBERT Academic Publishing, 2012.

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5

Kass, Erica, Jonathan E. Posner, and Laurence L. Greenhill. Pharmacological Treatments for Attention-Deficit/Hyperactivity Disorder and Disruptive Behavior Disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0004.

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More than 225 placebo-controlled type 1 investigations demonstrate that psychostimulants are highly effective in reducing core symptoms of attention-deficit/hyperactivity disorder (ADHD) in children and adults. In contrast, there are limited type I studies demonstrating that psychopharmacological management with U.S. Food & Drug Administration-approved agents for ADHD (stimulants and nonstimulants), atypical antipsychotics, and mood stabilizers decrease the defiant and aggressive behavior characteristic of disruptive behavior disorders. Stimulant treatment evidence has been supplemented by

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6

Yennurajalingam, Sriram, and Eduardo Bruera. Fatigue and asthenia. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0081.

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Fatigue is the most frequent, complex, multidimensional, and debilitating symptom in patients with advanced medical conditions. In the majority of palliative care patients, the aetiology of fatigue is multifactorial and the most common factors associated with fatigue include anorexia/cachexia, anxiety, depression, shortness of breath, sleep disturbances, anaemia, and inflammation. Routine screening for fatigue is essential for optimal assessment of fatigue and history and investigations should always be individualized. Management should initially aim towards identification and treatment of the

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7

Medforth, Janet, Linda Ball, Angela Walker, Sue Battersby, and Sarah Stables. Medical conditions during pregnancy. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198754787.003.0010.

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This chapter comprises a review of common medical conditions, including asthma, thyroid conditions, cardiac conditions, and renal diseases. There is a small section on renal transplant and care of the woman during pregnancy. Insulin-dependent diabetes, non-insulin-dependent diabetes, gestational diabetes, and their impact on pregnancy are discussed. The effect of pregnancy on the conditions themselves is reviewed, along with recognition and management of pregnancy changes due to the condition. Pregnancy management options, including altered physiology and pharmacological treatment, are discuss

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8

Psycho-Pharmacological Investigation of Herbal Extracts Using Animal Models. Independently Published, 2020.

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9

Segraves, R. Taylor. Pharmacotherapy and Psychotherapy for Sexual Dysfunctions. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0022.

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Well-controlled, double-blind, multisite investigations have demonstrated the efficacy of phosphodiesterase type 5 inhibitors for the treatment of erectile problems of mixed etiologies. A large number of studies affirm that serotonergic antidepressants delay ejaculation in men with premature ejaculation. Similarly, studies have demonstrated the efficacy of transdermal testosterone therapy in restoring sexual function in women after oophorectomy. There is suggestive evidence of the efficacy of cognitive-behavioral therapy in the treatment of sexual dysfunction in both sexes. However, the number

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10

Welch, Killian A. Alcohol Abuse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0185.

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Unqualified, “alcohol” refers to ethyl alcohol (C2H5OH), the favored drug of much of the world’s population. It was probably discovered following experimental fermentation, and archaeological investigations suggest that beer was being habitually consumed earlier than 6000 BCE. Although often considered a “moral failing,” the neurobiological changes that underpin addiction to alcohol are increasingly understood. This has been accompanied by development of an increasing variety of interventions for alcoholism with demonstrated efficacy, these spanning the social, psychological, and pharmacologic

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Частини книг з теми "Pharmacological Investigations"

1

Jain, Vartika, and Surendra K. Verma. "Pharmacological Investigations and Toxicity Studies." In SpringerBriefs in Pharmacology and Toxicology. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-27904-1_4.

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Baia, Monica, Simion Astilean, and Traian Iliescu. "Other Molecules with Pharmacological Activity." In Raman and SERS Investigations of Pharmaceuticals. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-78283-4_7.

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3

Péan, C., A. Wijkhuisen, F. Djedaïni-Pilard, C. Créminon, J. Grassi, and B. Perly. "Pharmacological Investigations of New Peptido-Cyclodextrins." In Proceedings of the Ninth International Symposium on Cyclodextrins. Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4681-4_92.

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4

Wu, Hao, Eric J. Lien, and Linda L. Lien. "Chemical and pharmacological investigations of Epimedium species: A survey." In Progress in Drug Research. Birkhäuser Basel, 2003. http://dx.doi.org/10.1007/978-3-0348-8012-1_1.

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5

Shawon, Shahparan Islam, Rashmia Nargis Reyda, and Nazmul Qais. "Traditional Uses and Modern Pharmacological Investigations of Bidens frondosa and Bidens tripartita." In The Genus Bidens. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-96-4257-1_20.

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6

Golbs, S., M. Kuehnert, H. Zimmermann, and J. A. P. Donato. "Pharmacological-Toxicological Investigations with a Furan Derivative Produced from Sugar-Cane on Laboratory Animals." In Archives of Toxicology. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-74936-0_63.

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Vrbjar, Norbert, Stefan Zöllner, Reiner F. Haseloff, Margit Pissarek, and Ingolf E. Blasig. "PBN spin trapping of free radicals in the reperfusion-injured heart. Limitations for pharmacological investigations." In Myocardial Ischemia and Reperfusion. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4979-6_13.

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Zaman, Raihan Uz, Nazim Uddin Emon, Minhajul Islam, and Rashaduz Zaman. "Deciphering the Comparative Pharmacological Insights of Thysanolaena maxima, Diploclisia glaucescens, and Pterospermum semisagittatum: Chemico-Biological Investigations." In Engineering Design and Technical Applications of Physical Science. Apple Academic Press, 2025. https://doi.org/10.1201/9781003536819-23.

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Hidaka, Hisashi. "Conservative Treatment: Pharmacological Therapy." In Clinical Investigation of Portal Hypertension. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-10-7425-7_17.

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Bramucci, Ezio, and Diego Ardissino. "Pharmacological Investigation Using Invasive Methods." In Developments in Cardiovascular Medicine. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2628-5_8.

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Тези доповідей конференцій з теми "Pharmacological Investigations"

1

Tran, HT, EM Pferschy-Wenzig, N. Kretschmer, et al. "Investigations of the pharmacological properties of carvotacetones isolated from Sphaeranthus africanus." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399893.

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2

Silva, Letícia Freitas de Castro, Elisa Pinheiro Weber, Gleice Silva Toledo, and Josiane Fonseca Almeida. "New pharmacological strategies for the treatment of alzheimer’s disease." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.097.

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Introduction: Alzheimer’s disease (AD) is seen as the most important dementia, prevalent in the elderly over 60 years old. There is still no cure, and the pharmacological strategies are to delay the symptoms and development of the pathology. The pathophysiological mechanisms are: hyperphosphorylation of the tau protein and aggregation of amyloid-β. Update studies of the tested therapies target the main pathological mechanisms: accumulation of β amyloid (inhibitors and modulators of β-secretase and γ-secretase and active and passive anti-Aβ immunotherapies), tau protein (inhibition of abnormal

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3

Raab, P., and R. Bauer. "Phytochemical and pharmacological investigations of Albizia julibrissin DURAZZ. bark extract with respect to anti-inflammatory effects." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3400143.

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Rădulescu, Ionuţ Dragoș, Letiția Dobri Mirona, Codrina Moraru, Petronela Nechita, Ciprian Vlad, and Cezar Bichescu. "PHARMACOLOGICAL ADD-ON TREATMENTS IN MANAGING ANTIPSYCHOTIC-INDUCED WEIGHT GAIN." In The European Conference of Psychiatry and Mental Health "Galatia". Archiv Euromedica, 2023. http://dx.doi.org/10.35630/2022/12/psy.ro.24.

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Introduction: One of the most common antipsychotic (AP) related adverse drug reactions is weight gain, with a large proportion of patients started on AP even from the onset of schizophrenia, ending up gaining considerable weight. Aim: The study was designed to research current evidence for reducing weight gain through pharmacological supplementation or other practical interventions, in patients treated with APs. Method: A review of the published works found on MEDLINE and PubMed from 2015 to 2019 was done, concentrating mostly on research that specifically examined changes in body weight in in

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Mašulović, Aleksandra, Anita Lazić, Ivana Đorđević, et al. "Assessing the pharmacological potential of synthetic colorants with pyridone core." In 37th International Congress on Process Industry. SMEITS, 2024. http://dx.doi.org/10.24094/ptk.024.299.

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Azo dyes are known as structurally diverse class of organic compounds bearing one or more azo groups (–N=N–) as a bridge between organic residues of which at least one is an aromatic moiety. This group of synthetic dyes is obtained easily by the reaction of diazo coupling with high yield. The importance of azo dyes is reflected in the fact that they account for 60 % of the total number of the dye structures known to be manufactured and used in the coloration of textiles, leather, plastics and cosmetics. Aside from their traditional usage, azo dyes are known for their therapeutic properties and

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Madić, Višnja, Aleksandra Petrović, and Perica Vasiljević. "ETHNOPHARMACOLOGY OF DIABETES: FROM TRADITIONAL RECIPES TO MODERN MEDICINE." In 58. Kongres Antropološkog društva Srbije. Antropološko društvo Srbije, 2025. https://doi.org/10.46793/ads25.34m.

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Diabetes is one of the most prevalent chronic diseases of the 21st century. Current pharmacological interventions used in the management of this condition regulate hyperglycemia; however, they do not fully prevent the onset or progression of its secondary complications, including diabetic nephropathy, hepatic dysfunction, osteoporosis, neuropathy, retinopathy, cardiovascular diseases, increased risk of dementia, etc. Consequently, a growing number of individuals with diabetes, in addition to conventional pharmacotherapy, are incorporating herbal alternatives derived from traditional medicine,

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Levi, Russell, Saad Ahmed, and Zachary Harris. "Can Nutritional Supplements Benefit Patients Receiving Treatment for Neurodegenerative Disorders?" In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.53_2024.

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As the prevalence of neurocognitive disorders rises globally, developing new methodologies of prevention and treatment is crucial. This literature review examines the efficacy of adding nutritional supplements, specifically nootropics, with traditional pharmacological regimens on various neurocognitive and neurodegenerative disorders. Primary, peer-reviewed research, including both human and animal studies, was assesed to determine if there was a benefifical, minimal, or detrimental effect on symptom progression. The inclusion criteria focused on studies that evaluated the reduction in disease

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Spinella, Toni, Sherry Stewart, Julia Naugler, Igor Yakovenko, and Sean Barrett. "The power of placebo: Does cannabidiol (CBD) expectancy alone impact acute stress and anxiety?" In 2022 Annual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2022. http://dx.doi.org/10.26828/cannabis.2022.02.000.01.

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Background. There have been notable increases in the use of cannabidiol (CBD) for therapeutic purposes, such as in the treatment of stress- and anxiety- related disorders. Preliminary research has demonstrated that CBD decreases indices of stress and anxiety. However, drug effects in humans are thought to be comprised of both pharmacological properties as well as a placebo response. Little is known about the extent to which the purported therapeutic effects of CBD result from pharmacological versus expectancy factors. Aims. The aim of this study was to evaluate whether (i) CBD expectancy alone

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Tóth, B., N. Kúsz, N. Bózsity, et al. "Phytochemical and pharmacological investigation of Sideritis montana L." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608120.

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"O-036 - CLINICAL DIFFERENCES BETWEEN PATIENTS WITH AND WITHOUT SUBSTANCE-INDUCED PSYCHOTIC SYMPTOMS WHO HAVE A LIFETIME MAJOR DEPRESSIVE DISORDER AND A SUBSTANCE USE DISORDER." In 24 CONGRESO DE LA SOCIEDAD ESPAÑOLA DE PATOLOGÍA DUAL. SEPD, 2022. http://dx.doi.org/10.17579/abstractbooksepd2022.o036.

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INTRODUCTION Patients with lifetime major depressive disorder (MDD) and substance use disorder (SUD) have a more severe clinical presentation compared to MDD patients without SUD (1). Substance-induced psychotic symptoms (SIPS) are clinically relevant as may be related to worse prognosis and mortality (2); however, little is known about SIPS in patients with lifetime MDD. OBJECTIVE this research pretends to describe clinical characteristics in MDD patients with SIPS. METHODS A cross-sectional study was performed by evaluating sociodemographic and clinical features in adult patients with SUD an

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Звіти організацій з теми "Pharmacological Investigations"

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Kennedy, Sara M., and Rania Ali. Baclofen for Alcohol Use Disorder: A Cochrane Review Summary With Commentary. RTI Press, 2025. https://doi.org/10.3768/rtipress.2025.rb.0040.2502.

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This brief summarizes the Cochrane Review, “Baclofen for Alcohol Use Disorder,” by R. Agabio, R. Saulle, S. Rösner, and S. Minozzi (https://doi.org/10.1002/14651858.CD012557.pub3). The Cochrane Review examines evidence for benefits and harms of baclofen on achieving and maintaining abstinence or reducing alcohol consumption in people with alcohol use disorder (AUD) compared to placebo, no treatment, or any other pharmacological relapse prevention treatment. Review authors conclude that baclofen likely reduces the risk of relapse to any drinking and increases the percentage of abstinent days, m

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