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Дисертації з теми "Phytochemical And Anti-Microbial Analysis"

Автор: Grafiati

Опубліковано: 7 червня 2025

Оновлено: 2 серпня 2025

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1

Adefuye, Ogheneochuko Janet. "Anti-diabetic and phytochemical analysis of sutherlandia frutescens extracts." Thesis, Nelson Mandela Metropolitan University, 2016. http://hdl.handle.net/10948/3549.

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In Africa, the importance of medicinal plants in folklore medicine and their contribution to primary healthcare is well recognized. Across the continent, local herbal mixtures still provide the only therapeutic option for about 80% of the population. The vast floral diversity and the intrinsic ethnobotanical knowledge has been the backbone of localized traditional herbal medical practices. In Africa, an estimated 5400 of the 60000 described plant taxa possess over 16300 therapeutic uses. Similarly, with a therapeutic flora comprising of approximately 650 species, herbal medical practitioners i

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2

Loonat, Firdows. "Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta Graveolens L. in mice and rats." Thesis, University of the Western Cape, 2012. http://hdl.handle.net/11394/4379.

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Magister Pharmaceuticae - MPharm<br>Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta graveolens L. in mice and rats FIRDOWS LOONAT M. Pharm. Pharmaceutical Sciences thesis: School of Pharmacy, University of the Western Cape Ruta graveolens (Rutaceae) L. is a medicinal plant that is commonly used to manage and treat essential events such as pain, inflammation and fever. Despite its popularity, particularly as a medicinal plant in the Calvinia district and Bredasdorp region of South Africa, scientific data to substantiate its widespread traditional use and

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3

Seanego, Christinah Tshephisho. "Phytochemical analysis and bioactivity of Garcinia Kola (Heckel) seeds on selected bacterial pathogens." Thesis, University of Fort Hare, 2012. http://hdl.handle.net/10353/420.

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Garcinia kola is one of the plants used in folklore remedies for the treatment of microbial infections. Bacterial resistance to commonly used antibiotics has necessitated the search for newer and alternative compounds for the treatment of drug resistant microbial infections. This study focuses on the bioactivity of G. kola seeds on Streptococcus pyogenes (ATCC 49399), Staphylococcus aureus (NCTC 6571), Plesiomonas Shigelloides (ATCC 51903) and Salmonella typhimurium (ATCC 13311), organisms which can cause illnesses from mild to severe with potentially fatal outcomes. The crude ethyl acetate, e

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4

Nyenje, Mirriam E. "Phytochemical analysis and bioactivity of the stem bark of Combretum Molle on some selected bacterial pathogens." Thesis, University of Fort Hare, 2011. http://hdl.handle.net/10353/391.

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Antimicrobial resistance is a worldwide problem that has deleterious long-term effects as the development of drug resistance outpaces the development of new drugs. Plants have been used for many generations for healing purposes, and screening of extracts of these plants has often yielded positive outcomes. This study was aimed at isolating and characterizing the major active antimicrobial compounds present in the stem bark of C. molle, in a bid to identify potential sources of cheap starting materials for the synthesis of new drugs. Various solvents (hexane, ethyl acetate, dichloromethane, ace

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5

Nethathe, Bono Bianca. "Bioactivity and phytochemical analysis of Hydnora Africana on some selected bacterial pathogens." Thesis, University of Fort Hare, 2011. http://hdl.handle.net/10353/d1001063.

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Abstract Medicinal plants have been for long remedies for human diseases because they contain components of therapeutic value. The growing problem of antibiotic resistance by organisms demands the search for novel compounds from plant based sources. The present study was aimed at evaluating the bioactivity and phytochemical analysis of Hydnora africana on clinical and standard strains of Helicobacter pylori (PE 252C and ATCC 43526), Aeromonas hydrophila ATCC 35654, and Staphylococcus aureus NCT 6571 in an effort to identify potential sources of cheap starting materials for the synthesis of new

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6

Chang, Chen J. B. "A hexa-herbal Chinese formula for treatment of atopic dermatitis : phytochemical analysis and selected anti-inflammatory activities." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1560129/.

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Diverse pharmacological activities and the solid clinical performance of Chinese herbal medicines have attracted worldwide attention in terms of its modernization. Here, a hexaherbal Chinese formula (HHCF) for treating atopic dermatitis (AD) topically has been studied from chemical and biological perspectives. The HHCF comprises the rootstock of Scutellaria baicalensis Georgi (SCU), Rheum tanguticum Maxim. Ex Balf. (RHE), Sophora flavescens Aiton (SOP); the root bark of Dictamnus dasycarpus Turcz. (DIC); the bark of Phellodendron chinense C.K. Schneid. (PHE) and the fruit of Kochia scoparia (L

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7

Perera, Muthukuttige. "Phytochemical analysis of two Australian native plants and their effects on chronic wound healing." Thesis, Queensland University of Technology, 2022. https://eprints.qut.edu.au/229994/1/Muthukuttige%20Madusha%20Nuwanthi_Perera_Thesis.pdf.

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Chronic wounds are a significant burden to national health services worldwide and a potential reason for patients’ declining quality of life. As such, this project focused on assessing the therapeutic effect of two Australian native plants, Alocasia macrorrhizos and Syncarpia hillii for their potential in chronic wound healing, through investigating their antibacterial, anti-inflammatory, and regenerative properties.

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8

Tshitenge, Tshitenge Dieudonné [Verfasser], and Gerhard [Gutachter] Bringmann. "Isolation and Structural Elucidation of Novel Anti-Infective Naphthylisoquinoline Alkaloids from Ancistrocladus ealaensis, and Phytochemical Analysis of Two Congolese Medicinal Plants / Dieudonné Tshitenge Tshitenge ; Gutachter: Gerhard Bringmann." Würzburg : Universität Würzburg, 2019. http://d-nb.info/1197537953/34.

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9

Pham, Hoang-Nam. "Impact des métabolites secondaires de plantes sur des bactéries pathogènes de la rhizosphère : existe-t-il un lien entre la résistance sur métaux et la modulation de résistance aux antibiotiques ?" Thesis, Toulouse 3, 2017. http://www.theses.fr/2017TOU30153/document.

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L'objectif de cette thèse est d'évaluer les modifications du métabolisme secondaire des plantes contaminées aux éléments trace métalliques (ETM) et leurs conséquences sur les communautés bactériennes rhizosphériques associées incluant des bactéries présentant des phénotypes de MultiDrug Résistance (MDR). Nous nous sommes focalisés sur deux contextes de sols exposés aux métaux : la phytoremédiation de sites miniers au Vietnam et la reconversion de sols agricoles contaminés par la re-déposition atmosphérique d'activités métallurgiques en France. Nos résultats ont mis en évidence que la contamina

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10

Nqolo, Nandipha Lucia. "Phytochemical study of Rhoicissus tomentosa." Thesis, University of the Western Cape, 2008. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_3223_1263940394.

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<p>This investigation focused on Rhoicissus tomentosa, belonging to the family, Vitaceae in an attempt to assess the phytochemistry of this plant which is widely used by traditional healers in South Africa to ensure the safe delivery during pregnancy and childbirth (Hutchings et al., 1996).</p>

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11

Kouloura, Eirini. "Phytochemical investigation of Acronychia species using NMR and LC-MS based dereplication and metabolomics approaches." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05P636/document.

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Анотація:

Les plantes médicinales constituent une source inexhaustible de composés (des produits naturels - PN) utilisé en médecine pour la prévention et le traitement de diverses maladies. L'introduction de nouvelles technologies et méthodes dans le domaine de la chimie des produits naturels a permis le développement de méthodes ‘high throughput’ pour la détermination de la composition chimique des extraits de plantes, l'évaluation de leurs propriétés et l'exploration de leur potentiel en tant que candidats médicaments. Dernièrement, la métabolomique, une approche intégrée incorporant les avantages des

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12

Aldis, Gary. "Analysis of the infant gut microbiota and investigation of bifidobacterial diversity and anti-microbial activity." Thesis, University of Reading, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.632825.

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Selected bacterial groups within the infant gut micro biota were investigated in relation to mode of delivery, initial diet (i.e. breast-fed versus formula-fed) and weaning. Colonic bacteria from 50 faecal samples (obtained from 30 infants during the milk-fed and, post-weaning phases) were enumerated by fluorescence in situ hybridisation. The probes used were as follows: Bac 303 (bacteroides), Bif 164 (bifidobacteria), Chis 150 (Clostridium clusters I and II), Erec 482 (Clostridium cluster XIVa), EC 1531 (Escherichia coli), Lab 158 (lactobacilli/enterococci group) and the DAPI nucleic acid sta

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13

Hall, Braydon. "A Multivariate Approach to Integration of Ethnobotanical, Pharmacological, and Phytochemical Analyses of Cree and Squamish Traditional Herbal Medicines for Anti-Diabetes Use." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39248.

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This thesis investigated the integration of pharmacological and phytochemical data of medicinal plants from the Cree of Eeyou Istchee in Northern Quebec. Data from these 17 plant extracts were assessed for patterns of biological activity and chemical signals that could be explained by taxonomic or plant organ groupings. The Squamish medicinal plant Oplopanax horridus (Sm.) Miq. was also assessed for enzyme inhibition activity across multiple extracts and for bioactive compounds using an untargeted metabolomics approach. A comprehensive data set was assembled documenting the relative activit

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14

Nelson, Geoffrey Winston. "Surface characterization and functional properties of carbon-based materials." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:f22b95ce-65f3-4d9e-ac3d-a88f6e142c1a.

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Carbon-based materials are poised to be an important class of 21st century materials, for bio-medical, bio-electronic, and bio-sensing applications. Diamond and polymers are two examples of carbon-based materials of high interest to the bio-materials community. Diamond, in its conductive form, can be used as an electrochemical bio-sensor, whilst its nanoparticle form is considered a non-inflammatory platform to deliver drugs or to grow neuronal cells. Polymers, especially when chemically modified, have been used extensively in biological environments, from anti-microbial use to drug delivery.

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15

Mboweni, Hlayisa Fredah. "Antimicrobial, cytotoxic and prelimenary phytochemical analysis of four medicinal plants and their formulation." Diss., 2018. http://hdl.handle.net/11602/1096.

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MSc (Microbiology)<br>Department of Microbiology<br>BACKGROUND: Medicinal plants form an important part of the Southern African cultural heritage. Indigenous populations, for example the Vha-Venda people, tend to use medicinal plants in formulations rather than western medicines for health and survival. In order to certify and give scientific credibility to the use of medicinal plants formulations used by Vha-Venda people for the treatment of diseases, several assays were carried out. The present study was aimed at assessing phytochemical content, antimicrobial, antioxidant and cytotoxic

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16

Tshitenge, Tshitenge Dieudonné. "Isolation and Structural Elucidation of Novel Anti-Infective Naphthylisoquinoline Alkaloids from Ancistrocladus ealaensis, and Phytochemical Analysis of Two Congolese Medicinal Plants." Doctoral thesis, 2019. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-154175.

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Анотація:

Herein described are the isolation, structural elucidation, and biological evaluation of highly thrilling monomeric and dimeric new naphthylisoquinoline alkaloids from A. ealaensis. The separation, chiral resolution, and characterization of a series of stereoisomeric 2,3-dihydrobenzofuran neolignans are also reported. The analytical and phytochemical analysis on two Congolese antimalarial herbal drugs is part of the last chapter of the results. In this last case, major concerns on widely used Congolese herbal drugs are discussed<br>Im Rahmen dieser Dissertation werden Einblicke in die struktur

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17

Moolla, Aneesa. "A phytochemical and pharmacological investigation of indigenous agathosma species." Thesis, 2006. http://hdl.handle.net/10539/1637.

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Faculty of Sciences School of Pharmacy and Pharmacology 0000073k moollaaneesa@yahoo.com<br>As part of an investigation of the biological activities of South African plants and due to their extensive traditional use and lack of scientific evidence, a phytochemical and pharmacological investigation was performed on 17 indigenous Agathosma species (19 samples). The chemical composition of the essential oils was determined using gas chromatography coupled to mass spectroscopy (GC-MS). Analysis resulted in the identification of 333 compounds. To evaluate the chemical similarities and diffe

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18

Turner, Dee Ann. "Monitoring, characterizing, and preventing microbial degradation of ignitable liquids on soil." Thesis, 2013. http://hdl.handle.net/1805/5046.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Organic-rich substrates such as soil provide an excellent carbon source for bacteria. However, hydrocarbons such as those found in various ignitable liquids can also serve as a source of carbon to support bacterial growth. This is problematic for fire debris analysis as samples may be stored at room temperature for extended periods before they are analyzed due to case backlog. As a result, selective loss of key components due to bacterial metabolism can make identifying and classifying ignitable liquid residues by their chemical comp

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19

"Selection of resistant strains of Salmonella, Escherichia coli and Pseudomonas aeruginosa by antimicrobial agents." 2004. http://library.cuhk.edu.hk/record=b5892152.

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Ko Mui Lam.<br>Thesis submitted in: December 2003.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.<br>Includes bibliographical references (leaves 84-100).<br>Abstracts in English and Chinese.<br>Chapter Chapter 1 --- Introduction --- p.1<br>Chapter A. --- Antibiotic use and resistance --- p.1<br>Chapter B. --- Selection of resistant strains by antibiotics --- p.2<br>Chapter C. --- Fluoroquinolones --- p.5<br>Chapter D. --- β-Lactams --- p.8<br>Chapter E. --- Aminoglycosides --- p.9<br>Chapter F. --- Salmonella sp --- p.9<br>Chapter a. --- Microbiology and clinical significan

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20

Chaitra, M. G. "T Cell Epitopes Of PE And PPE Family Of Proteins Of Mycobacterium Tuberculosis And Analysis Of Their Vaccine Potential." Thesis, 2007. https://etd.iisc.ac.in/handle/2005/651.

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Анотація:

One-third of the world’s population is latently infected with Mycobacterium tuberculosis, which causes over 2 million deaths every year. The current live attenuated vaccine, Bacille Calmette-Guerin (BCG), protects against miliary tuberculosis in children, but fails to consistently protect against pulmonary tuberculosis in adults. The global resurgence of tuberculosis, together with the HIV pandemic and emerging multi-drug resistance, has heightened the need for an effective vaccine. Completion of the M. tuberculosis genome sequence paved way for identification of many new candidate antigens

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21

Chaitra, M. G. "T Cell Epitopes Of PE And PPE Family Of Proteins Of Mycobacterium Tuberculosis And Analysis Of Their Vaccine Potential." Thesis, 2007. http://hdl.handle.net/2005/651.

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Анотація:

One-third of the world’s population is latently infected with Mycobacterium tuberculosis, which causes over 2 million deaths every year. The current live attenuated vaccine, Bacille Calmette-Guerin (BCG), protects against miliary tuberculosis in children, but fails to consistently protect against pulmonary tuberculosis in adults. The global resurgence of tuberculosis, together with the HIV pandemic and emerging multi-drug resistance, has heightened the need for an effective vaccine. Completion of the M. tuberculosis genome sequence paved way for identification of many new candidate antigens f

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