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Готові списки джерел за темами / Protein X / Дисертації

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Дисертації з теми "Protein X"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Abhiman, Saraswathi. "Prediction of function shift in protein families /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-869-X/.

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2

Schwardt, Malte. "BDV X protein is a non-structural protein." [S.l. : s.n.], 2006. http://nbn-resolving.de/urn:nbn:de:bsz:25-opus-60677.

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3

Lindström, Mikael. "Functional characterization of the alternative reading frame protein p14ARF /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-917-x.

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4

Nagy, Noémi. "Expression and function of the small immune adaptor protein SAP /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7357-029-X/.

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5

Edwards, Todd Criswell. "Self-assembly of proteins at interfaces and two-dimensional protein crystallization /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/8093.

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6

Wall, Clare. "Mathematical methods in protein x-ray crystallography." Thesis, University of York, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403863.

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7

Skoging, Nyberg Ulrica. "Protein interactions involved in alphavirus assembly /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4329-x/.

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8

Asuru, Awuri P. "Applications of X-ray Hydroxyl Radical Protein Footprinting." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1575877091577049.

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9

Callan, Matthew Aron. "Novel Roles for Fragile X Protein in Neurogenesis." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/145454.

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Анотація:

Fragile X Syndrome (FXS) is the most common form of inherited mental retardation, affecting approximately 1/4000 males and 1/6000 females worldwide. FXS is caused by loss of FMR1 gene expression, resulting in the lack of the protein product, Fragile X protein (FMRP). FMRP is an RNA-binding protein thought to regulate synaptic plasticity by controlling the localization and translation of specific mRNAs in neurons. To determine whether FMRP is also required in early brain development we examined the distribution of cell cycle markers in Drosophila FMR1 (dFmr1) mutant brains compared to wild-type

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10

Stenberg, Leisa M. "Expression and characterization of a recombinant human factor X/protein C chimeric protein." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0015/NQ46432.pdf.

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11

Astorga-Wells, Juan. "Microfluidic electrocapture technology in protein and peptide analysis /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-965-x/.

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12

Oppermann, Madalina. "Chemical and mass spectrometrical methods in protein analysis /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4542-x/.

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13

Chagas, Ricardo Alexandre Ventura. "Proteome-metabolite interactions in wine. Tracking down the X factor." Master's thesis, ISA, 2010. http://hdl.handle.net/10400.5/3329.

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Mestrado em Viticultura e Enologia - Instituto Superior de Agronomia<br>Protein haze formation is a recurrent problem in white and rosé wines. Formation of his type of haze is dependent on only for the protein content of the wine, but is strictly related to one or more non-proteinaceous wine components termed as X factor. A selected wine from the variety Moscatel of Alexandria was fractionated using a preparative RP-18 chromatography column in eight methanolic fractions that were subsequently subjected to heat stability test with wine isolated protein in model wine solution. The results obtain

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14

Evers, Florian [Verfasser]. "Proteins at interfaces : protein adsorption studied by X-ray and neutron reflectometry / Florian Evers." Dortmund : Universitätsbibliothek Technische Universität Dortmund, 2011. http://d-nb.info/1011568373/34.

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15

Bisiak, Francesco. "Structural studies of the Roundabout protein family." Thesis, Université Grenoble Alpes (ComUE), 2018. http://www.theses.fr/2018GREAV006/document.

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Les systèmes neuronaux et vasculaires nécessitent un réseau complexe pour exécuter correctement leurs fonctions. Les processus impliqués dans la création de ce réseau s'appuient sur des voies coordonnées, souvent activées par des systèmes protéine/récepteur communs, qui conduisent au remodelage du cytosquelette.En général, les cellules neuronales et vasculaires répondent aux stimuli extracellulaires sous forme de protéines solubles sécrétées, qui interagissent avec les récepteurs de surface pour favoriser l'attraction ou la répulsion vers la source des protéines sécrétées. Ce processus, appelé

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16

Ahuja, Sanjay. "Development of a recombinant protein vaccine against Plasmodium falciparum malaria /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-788-X/.

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17

Olsson, Per-Anders. "MIR, a novel ERM-like protein in the nervous system." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5061-X/.

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18

Leonchiks, Ainars. "Regulation of protein degradation by virus derived repeated amino acid sequences /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-206-x/.

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19

Wu, Xiaoqiu. "Functional genomics at the interface of protein expression and biophysical analysis /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-772-X.

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20

Schulte, Gunnar. "Adenosine receptor signaling and the activation of mitogen-activated protein kinases /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-299-x/.

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21

Khayachi, Anouar. "Rôles fonctionnels de la SUMOylation de FMRP « Fragile X Mental Retardation Protein »." Thesis, Nice, 2015. http://www.theses.fr/2015NICE4031.

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Анотація:

Le syndrome de l’X-fragile est la forme la plus fréquente de déficience intellectuelle héréditaire liée au chromosome X. Cette maladie résulte de la mutation du gène FMR1 localisé sur le chromosome X. La protéine correspondante, FMRP, est absente chez les patients atteints de la maladie. Il faut noter ici qu’il existe un modèle murin mimant la pathologie humaine. Ainsi dans ces animaux qui n’expriment pas la protéine FMRP, les neurones présentent des anomalies architecturales de la synapse entraînant d’importants dysfonctionnements dans la transmission et la plasticité synaptique qui sont à l’

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22

Haire, Lesley Findlay. "Strategies for protein crystal growth-screening and optimization." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243778.

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23

Van, Benschoten Andrew Holland. "Mapping and modeling X-ray diffuse scattering from protein crystals." Thesis, University of California, San Francisco, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3714309.

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Анотація:

<p> Understanding the physical basis of enzyme dynamics is a major challenge in biology. Although modeling the motion of individual atoms is straightforward, combining these movements into descriptions of macromolecular function proves more difficult. X-ray crystallography produces atomic-level visualizations of an ensemble of countless molecules; however, current methods capture only the average protein conformation and thus cannot completely describe the underlying dynamics. A parallel source of information, diffuse scattering, is present in diffraction images and directly reports on correla

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24

Hillgren, Anna. "Investigation of the Freeze-Thawing Process for Pharmaceutical Formulations of a Model Protein." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5304-X/.

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25

Khayachi, Anouar. "Rôles fonctionnels de la SUMOylation de FMRP « Fragile X Mental Retardation Protein »." Electronic Thesis or Diss., Nice, 2015. http://www.theses.fr/2015NICE4031.

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Анотація:

Le syndrome de l’X-fragile est la forme la plus fréquente de déficience intellectuelle héréditaire liée au chromosome X. Cette maladie résulte de la mutation du gène FMR1 localisé sur le chromosome X. La protéine correspondante, FMRP, est absente chez les patients atteints de la maladie. Il faut noter ici qu’il existe un modèle murin mimant la pathologie humaine. Ainsi dans ces animaux qui n’expriment pas la protéine FMRP, les neurones présentent des anomalies architecturales de la synapse entraînant d’importants dysfonctionnements dans la transmission et la plasticité synaptique qui sont à l’

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26

Ekström, Fredrik. "X-ray characterization of PaPheOH, a bacterial phenylalanine hydroxylase /." Umeå : Univ, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100.

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27

Werschallová, Markéta. "Mutační analýza obalového proteinu X viru bramboru (PVX)." Master's thesis, Česká zemědělská univerzita v Praze, 2016. http://www.nusl.cz/ntk/nusl-258763.

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The thesis deals with the mutational analysis of conserved amino acids of Potato virus X coat protein (PVX CP). The importance of selected amino acids for the spread of the virus in the plant should be determined. Nicotiana benthamiana was selected as an experimental plant. Mutations of the PVX CP were based on the comparison of PVX CP amino acid sequence with the sequence of Papaya mosaic virus coat protein (PapMV CP), the only representative of potexvirus, which includes PVX, with the described crystal structure of the CP. The importance of certain amino acids for interaction of coat prote

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28

Cook, Denise. "Fragile X related protein 1 associates with the protein synthesis machinery and controls synaptic plasticity in mice." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119349.

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Анотація:

Long-lasting synaptic plasticity and memory storage rely on mRNA control mechanisms that allow for rapid changes in gene expression in response to synaptic activity. RNA-binding proteins, which affect the transport, stability and translational state of their target mRNAs, are an important component of these translational control mechanisms. Fragile X Related Protein 1 (FXR1P) is a member of the Fragile X family of RNA-binding proteins, which also includes Fragile X Mental Retardation Protein (FMRP) and Fragile X Related Protein 2 (FXR2P). FXR1P is known to both repress and enhance the translat

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29

NAPOLI, ILARIA. "How the fragile X mental retardation protein represses protein synthesis: a mechanism of translational control in dendrites." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/765.

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Анотація:

La Sindrome dell'X Fragile è la forma di ritardo mentale ereditario più frequente nella popolazione con un'incidenza 1/4000 nei maschi e 1/6000 nelle femmine. La patologia è causata da mutazioni nel gene FMR1 il cui prodotto proteico, FMRP, è altamente espresso nei neuroni. FMRP è una proteina che lega gli RNA messaggeri neuronali e si localizza lungo i dendriti e gli assoni dei neuroni dove controlla il trasporto e la sintesi proteica dei messaggeri associati. Nel presente progetto abbiamo analizzato il meccanismo attraverso il quale FMRP regola la sintesi proteica alle sinapsi, caratteri

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30

Lewis, Richard. "X-ray crystallographic studies of fragments of DNA gyrase B protein." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320653.

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31

Tate, Graeme. "New methods in protein X-ray crystallography using maximum entropy techniques." Thesis, University of Glasgow, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396507.

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32

Verheij, Coleta. "Characterization of the FMR1 protein involved in the fragile X syndrome." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 1996. http://hdl.handle.net/1765/13734.

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33

Desai, Birju. "Expression and molecular interactions of retinoid X receptors in neuroblastoma cells." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324792.

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34

Cockburn, Ingrid Louise. "Modulation of Plasmodium falciparum chaperones PfHsp70-1 and PfHsp70-x by small molecules." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/d1001747.

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Анотація:

The heat shock proteins of ~ 70 kDa (Hsp70s) are a conserved group of molecular chaperones important in maintaining the protein homeostasis in cells, carrying out functions including refolding of misfolded or unfolded proteins. Hsp70s function in conjunction with a number of other proteins including Hsp40 cochaperones. Central to the regulation Hsp70 activity is the Hsp70 ATPase cycle, involving ATP hydrolysis by Hsp70, and stimulation of this ATP hydrolysis by Hsp40. PfHsp70-1, the major cytosolic Hsp70 in the malaria parasite, Plasmodium falciparum, and PfHsp70-x, a novel malarial Hsp70 rece

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35

Morris, Darryl William Seymour. "Low angle protein phasing." Thesis, University of York, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341631.

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36

Bray, Terry Lee. "A novel device for growing protein crystals : computer control and automation." Thesis, Georgia Institute of Technology, 1990. http://hdl.handle.net/1853/30428.

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37

Sargsyan, Ernest. "Characterization of ERp29, a novel secretion factor of endoplasmic reticulum /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-337-X/.

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38

Nicholson, James Martin. "Structural transitions in cobalt-insulin investigated with semi-time resolved cryocrystallography and high pressure crystallography." Thesis, Liverpool John Moores University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361509.

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39

Delgado, Malcom Arturo. "Biochemical Study of Engineered Fluorescent Proteins as Calcium Sensors and the Effect of Calcium and PH in Cell Reproduction and Protein Expression." Digital Archive @ GSU, 2009. http://digitalarchive.gsu.edu/chemistry_theses/23.

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Calcium plays important roles in both eukaryotic and prokaryotic cells. Its actions help to stabilize cell synthesis, growth and development. In this thesis, studies have been completed to determine effects of calcium and pH on bacterial cell growth and protein expression using the bacterial cell strain E.coli BL21(DE3). Our studies demonstrated the addition of calcium addition in the media does not affect growth but increases protein expression, while reducing the pH from 7 to 4 through the addition of 10mM EGTA in LB media inhibits both. Additionally, we report studies on the design, express

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40

Sinotte, Christopher Matthew. "Construction, expression, and purification of soluble CD16 in bacteria." Thesis, Available online, Georgia Institute of Technology, 2006, 2006. http://etd.gatech.edu/theses/available/etd-05142006-222347/.

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Анотація:

Thesis (M.S.)--Bioengineering, Georgia Institute of Technology, 2007.<br>Zhu, Cheng, Committee Chair ; Selvaraj, Periasamy, Committee Member ; Orville, Allen, Committee Member ; Butera, Robert, Committee Member.

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41

Ng, Florence Wai Hung. "Identification and characterization of Bcl-2/Bcl-X¦L interacting protein, p28Bap31." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0015/NQ44531.pdf.

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42

Allendorph, George P. "X-ray crystallographic and biochemical studies on the bone morphogenetic protein family." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3272812.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed September 4, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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43

Savage, Jason Eric. "Investigating a putative non structural protein of the birnavirus Drosophila-X virus." College Park, Md. : University of Maryland, 2004. http://hdl.handle.net/1903/1841.

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Thesis (M.S.) -- University of Maryland, College Park, 2004.<br>Thesis research directed by: Dept. of Cell Biology and Molecular Genetics. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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44

Whitman, Samantha. "Fragile X Related Protein-1 (FXR1) Regulates RNA Metabolism in Striated Muscle." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/195153.

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Анотація:

Cardiac muscle function necessitates the meticulous assembly and interactions of several cytoskeletal and regulatory proteins into specialized structures that orchestrate contraction and transmission forces. Despite extensive studies identifying the protein components responsible for these important aspects of heart development, putative RNA based mechanisms remain poorly understood, even with their demonstrated importance in other tissues. Evidence suggests that post-transcriptional regulation is critical for muscle function, but the molecular players involved (RNA binding proteins and mRNA t

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45

Dalla, Pietà Anna. "Natural Polymer X (NPX): A Novel Adjuvant For Protein-based Vaccination Strategies." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3426682.

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The emerging popularity of subunit vaccines that are constituted by poorly immunogenic synthetic and recombinant antigens, has underlined the importance of discovering new and potent adjuvants able to modulate, enhance, and extend the immune response against these antigens. Many different classes of adjuvants are currently under development in pre-clinical or clinical stage, but only a few are licensed for clinical use. The class of natural polymers (NPs) is emerging as a promising alternative among adjuvant formulations; thanks to their chemical and physical properties and their potential for

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46

Watkins, Jason Derrick. "X-ray structures of P22 c2 repressor-DNA complexes the mechansism of direct and indirect readout /." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/26709.

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Анотація:

Thesis (Ph.D)--Chemistry and Biochemistry, Georgia Institute of Technology, 2009.<br>Committee Chair: Loren D. Williams; Committee Member: Donald Doyle; Committee Member: Nicholas V. Hud; Committee Member: Roger Wartell; Committee Member: Stephen Harvey. Part of the SMARTech Electronic Thesis and Dissertation Collection.

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47

Schenck, Annette. "CYFIP, a protein family implicated in neuronal connectivity, links Rac1 GTPase signalling to the fragile X mental retardation protein." Université Louis Pasteur (Strasbourg) (1971-2008), 2003. http://www.theses.fr/2003STR13175.

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Анотація:

Le syndrome de l'X Fragile, qui constitue la forme la plus fréquente de retard mental héréditaire, est du à l'absence de FMRP, une protéine de liaison à l'ARN qui régulerait la traduction au niveau synaptique. Afin de mieux comprendre le role de FMRP, nous avons réalisé un criblage double-hybride dans la levure pour identifier certains de ses interacteurs. Deux protéines ont été isolées, CYFIP1 et CYFIP2 (Cytoplasmic FMRP Interacting Proteins 1/2). Ces deux protéines cytoplasmiques sont hautement homologues mais interagissent différement avec les deux autres protéines de la famille FXR, FXR1P

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48

Lee, Seung-Joo. "Structural and functional consequences of disease-related protein variants." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1269545015.

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49

Henne, Randal Marlow. "Computational studies of G-protein coupled receptors /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/8048.

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50

Henkler, Frank. "The hepatitis B virus X transcriptional activator protein and tumorigenesis in human liver." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267842.

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