Готові списки джерел за темами / SERPINH1

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Добірка наукової літератури з теми "SERPINH1"

Автор: Grafiati

Опубліковано: 7 липня 2024

Оновлено: 31 липня 2025

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Статті в журналах з теми "SERPINH1"

Al-Khatib, Sohaib M., Ayah N. Al-Bzour, Mohammad N. Al-Majali, et al. "Exploring Genetic Determinants: A Comprehensive Analysis of Serpin B Family SNPs and Prognosis in Glioblastoma Multiforme Patients." Cancers 16, no. 6 (2024): 1112. http://dx.doi.org/10.3390/cancers16061112.

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Serpins are serine proteinase inhibitors, with several serpins being overexpressed in cancer cells. Thus, we aim to analyze the single-nucleotide polymorphism (SNP) of Serpinb11 and its association with GBM survival. A cohort of 63 GBM patients recruited from King Abdullah University Hospital in Jordan underwent polymorphism analysis and overall survival (OS) assessments. The Cancer Genome Atlas (GBM) cohort was useful for validation. We constructed a risk score using the principal component analysis for the following Serpin genes: Serpinb3, Serpinb5, Serpinb6, Serpinb11, and Serpinb12, and pa

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Jin, Xiao-Sheng, Lu-Xi Chen, Ting-Ting Ji, and Rong-Zhou Li. "SERPINH1 promoted the proliferation and metastasis of colorectal cancer by activating PI3K/Akt/mTOR signaling pathway." World Journal of Gastrointestinal Oncology 16, no. 5 (2024): 1890–907. http://dx.doi.org/10.4251/wjgo.v16.i5.1890.

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BACKGROUND Serpin peptidase inhibitor clade H member 1 (SERPINH1) was initially recognized as an oncogene implicated in various human malignancies. Nevertheless, the clinical relevance and functional implications of SERPINH1 in colorectal cancer (CRC) remain largely elusive. AIM To investigate the effects of SERPINH1 on CRC cells and its specific mechanism. METHODS Quantitative real-time polymerase chain reaction, western blotting analysis, The Cancer Genome Atlas data mining and immunohistochemistry were employed to examine SERPINH1 expression in CRC cell lines and tissues. A series of in-vit

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Haj, Amelia K., Sean J. Jurgens, Xin Wang, et al. "Rare Germline Loss-of-Function Variants in HSP47 ( SERPINH1) Are Associated with an Intermediate Osteogenesis Imperfecta Phenotype Characterized By Atopic Inflammation and Increased Risk of Thrombosis." Blood 142, Supplement 1 (2023): 3934. http://dx.doi.org/10.1182/blood-2023-189896.

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Background: There has been considerable interest in the collagen-specific chaperone HSP47 ( SERPINH1) as a potential drug target for the treatment of cirrhosis, fibrotic disease, and more recently, thrombosis (Thienel et al., Science 380, 178-187, 2023). While homozygous or compound heterozygous loss of function in SERPINH1 is known to cause a rare form of osteogenesis imperfecta (OI) in humans, little is known about the clinical effects of moderately decreased HSP47 activity. In order to assess the potential safety and efficacy of an antithrombotic strategy based on HSP47 blockade, we evaluat

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Liu, Qian, Yuanhao Peng, Wenbin Liu, and Xiangjian Luo. "SERPINH1 functions as a multifunctional regulator to promote the malignant progression of cervical cancer." PLOS One 20, no. 7 (2025): e0329007. https://doi.org/10.1371/journal.pone.0329007.

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Cervical cancer remains the second leading cause of female cancer mortality worldwide, with metastasis representing a critical therapeutic challenge. This study systematically reveals the key role of SERPINH1 (Serpin Family H Member 1) as a hub regulator of malignant progression in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC). Through analysis of TCGA-CESC datasets, we identified that high SERPINH1 expression is significantly correlated with poor prognosis and contributes to tumor progression by promoting cell proliferation, invasion, and metastatic phenotypes. In vi

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Mueller, S. K., A. L. Nocera, S. T. Dillon, T. A. Libermann, O. Wendler, and B. S. Bleier. "Tissue and Exosomal Serine Protease Inhibitors Are Significantly Overexpressed in Chronic Rhinosinusitis With Nasal Polyps." American Journal of Rhinology & Allergy 33, no. 4 (2019): 359–68. http://dx.doi.org/10.1177/1945892419831108.

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Background The fibrinolysis pathway has been previously implicated in the etiopathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). Objective The purpose of this study was (1) to explore protein derangements of selected protease inhibitors of the serpin superfamily in CRSwNP and (2) to correlate the protease inhibitor derangements of the fibrinolysis pathway in tissue with exosomal samples to evaluate the potential of an exosomal noninvasive “liquid biopsy” for CRSwNP. Methods Institutional review board approved study in which matched tissue and mucus exosomal proteins (SerpinB2,

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Zhang, Yin, Chun-Yuan Li, Wei Ge, and Yi Xiao. "Exploration of the Key Proteins in the Normal-Adenoma-Carcinoma Sequence of Colorectal Cancer Evolution Using In-Depth Quantitative Proteomics." Journal of Oncology 2021 (June 11, 2021): 1–19. http://dx.doi.org/10.1155/2021/5570058.

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Purpose. In most cases, the carcinogenesis of colorectal cancer (CRC) follows the normal-adenoma-carcinoma (N-A-C) sequence. In this study, we aimed to identify the key proteins in the N-A-C sequence. Methods. Differentially expressed proteins (DEPs) in normal, adenoma, and carcinoma tissues were identified using the Tandem Mass Tag- (TMT-) based quantitative proteomics approach. The landscape of proteomic variation in the N-A-C sequence was explored using gene set enrichment analysis (GSEA) and Proteomaps. Key proteins in the N-A-C sequence were identified, verified, and validated based on ou

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Bertram, Stefanie, Juliet Padden, Julia Kälsch, et al. "Novel immunohistochemical markers differentiate intrahepatic cholangiocarcinoma from benign bile duct lesions." Journal of Clinical Pathology 69, no. 7 (2016): 619–26. http://dx.doi.org/10.1136/jclinpath-2015-203418.

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AimsThe distinction between intrahepatic cholangiocarcinoma (ICC) and benign bile duct lesions can be challenging. Using our previously identified potential biomarkers for ICC, we examined whether these are useful for the differential diagnosis of ICC, bile duct adenoma and reactive bile duct proliferations in an immunohistochemical approach and identified a diagnostic marker panel including known biomarkers.MethodsSubjects included samples from 77 patients with ICC, 33 patients with bile duct adenoma and 47 patients with ductular reactions in liver cirrhosis. Our previously identified biomark

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Tahmasbpour, E., A. Philp, C. Thomson, M. Plit, and D. Darley. "Overexpression of SerpinB1 and SerpinH1 in Transbronchial Biopsies of Patients with Eosinophilia and Chronic Lung Allograft Dysfunction." Journal of Heart and Lung Transplantation 44, no. 4 (2025): S388—S389. https://doi.org/10.1016/j.healun.2025.02.834.

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Zhang, Yin, Chun-Yuan Li, Meng Pan, et al. "Exploration of the Key Proteins of High-Grade Intraepithelial Neoplasia to Adenocarcinoma Sequence Using In-Depth Quantitative Proteomics Analysis." Journal of Oncology 2021 (November 29, 2021): 1–13. http://dx.doi.org/10.1155/2021/5538756.

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Purpose. In this study, we aimed to provide a comprehensive description of typical features and identify key proteins associated with the high-grade intraepithelial neoplasia- (HIN-) adenocarcinoma (AC) sequence. Methods. We conducted tandem mass tag-based quantitative proteomic profiling of normal mucosa, HIN, and AC tissues. Protein clusters representative of the HIN-AC sequence were identified using heatmaps based on Pearson’s correlation analysis. Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Reactome analyses were performed using the Database for Annotation, Visu

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van Leeuwen, L. Leonie, Mitchel J. R. Ruigrok, Henri G. D. Leuvenink, and Peter Olinga. "Slice of Life: Porcine Kidney Slices for Testing Antifibrotic Drugs in a Transplant Setting." Transplantology 4, no. 2 (2023): 59–70. http://dx.doi.org/10.3390/transplantology4020007.

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Circulatory death donor (DCD) kidneys are increasingly used to enlarge the donor pool. These kidneys undergo ischemia-reperfusion injury, frequently leading to renal fibrosis. Transforming growth factor beta 1 (TGF-β1) and matrix metalloproteases have been identified as central mediators of fibrosis and inhibition of these targets could attenuate fibrosis. We studied whether galunisertib, doxycycline, taurine, and febuxostat alleviated fibrosis in precision-cut kidney slices (PCKS). PCKS were prepared from porcine kidneys that were exposed to 30 min of warm ischemia followed by 3 h of oxygenat

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Дисертації з теми "SERPINH1"

Furtado, Clara Fernanda Barbirato. "Investigação de mutações nos genes LEPRE1, CRTAP, PPIB, FKBP10, SERPINH1 e SERPINF1 causadoras da osteogênese imperfeita recessiva." Universidade Federal do Espírito Santo, 2015. http://repositorio.ufes.br/handle/10/4522.

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Made available in DSpace on 2016-08-29T15:34:42Z (GMT). No. of bitstreams: 1 tese_8279_Tese_Clara Fernanda Barbirato.pdf: 794712 bytes, checksum: 13290894bcf3053215336989ea116592 (MD5) Previous issue date: 2015-02-13<br>A Osteogênese Imperfeita (OI) é uma doença clínica e geneticamente heterogênea caracterizada, predominantemente, por fragilidade e deformidade ósseas e por fraturas recorrentes. A maioria dos casos de OI resulta de mutações autossômicas dominantes nos genes COL1A1 e COL1A2, que codificam as cadeias formadoras do colágeno tipo I, principal proteína dos ossos. Nos últimos

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Wegehaupt, Oliver Philipp [Verfasser], and Michael [Akademischer Betreuer] Köttgen. "BAG2, BAT3, DNAJB11, GNB2L1 und SERPINH1 interagieren in einem Netzwerk mit dem Polycystin-1-TRPP2-Signalmodul." Freiburg : Universität, 2016. http://d-nb.info/1122647816/34.

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Pierce, Charles. "The role of the gene SERPINH1 as a pharmacogenetic biomarker for choroidal neovascularization (CNV) responses to anti vascular endothelial growth factor (VEGF) treatment in clinical practice." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/417281/.

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Age related macular degeneration is the commonest cause of blindness in the western world and current treatment regimens represent a significant output for national health services. The disease process is multifactorial in origin and has a variable progression and response to current methods of treatment. A targeted approach with individualized therapy based on recognized biomarkers to predict disease outcome would be the ideal treatment modality. We plan to investigate the role of genes known to influence the progression of early AMD to the advanced stage (wet AMD) with emphasis on genes invo

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Prévot, Pierre-Paul. "Rôles de la protéine Iris dans l'accomplissement du repas sanguin de la tique Ixodes ricinus." Doctoral thesis, Universite Libre de Bruxelles, 2007. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210730.

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Les tiques sont des arthropodes ectoparasites obligatoires qui se nourrissent sur une grande variété de vertébrés sur une large partie du globe. Au cours de leur repas, les tiques sécrètent dans leur salive de nombreux facteurs leur permettant de contourner bon nombre des défenses de l’hôte. Bien que la littérature rapporte beaucoup d’informations au sujet des effets du repas de la tique sur l’hôte, la nature des facteurs actifs exprimés par les glandes salivaires de la tique est peu connue. Au cours d’anciens travaux au sein du laboratoire, le crible de deux banques d’ADN complémentaires - is

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Ulbricht, David, Jan Pippel, Stephan Schultz, René Meier, Norbert Sträter та John T. Heiker. "A unique serpin P1′ glutamate and a conserved β-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin)". Portland Press, 2015. https://ul.qucosa.de/id/qucosa%3A33439.

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SerpinA12 (vaspin) is thought to be mainly expressed in adipose tissue and has multiple beneficial effects on metabolic, inflammatory and atherogenic processes related to obesity. KLK7 (kallikrein 7) is the only known protease target of vaspin to date and is inhibited with a moderate inhibition rate. In the crystal structure, the cleavage site (P1-P1′) of the vaspin reactive centre loop is fairly rigid compared with the flexible residues before P2, possibly supported by an ionic interaction of P1′ glutamate (Glu379) with an arginine residue (Arg302) of the β-sheet C. A P1′ glutamate seems high

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Mkaouar, Héla. "Rôle des serpines, inhibiteurs de protéases à serine, du microbiote digestif humain dans les maladies inflammatoires de l'intestin." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS108.

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Les inhibiteurs des protéases à sérine (Serpins) constituent une classe d'enzymes très peu étudiée chez les bactéries. Dans ce travail de thèse nous nous sommes intéressés à l'étude des serpins provenant du microbiote intestinal et l'investigation de leur potentiel anti-inflammatoire pour le traitement des maladies inflammatoires chroniques de l'intestin (MICI) chez l'homme. Pour cela nous avons identifié les serpins provenant du microbiote intestinal humain et analysé leur diversité ainsi que leur distribution entre les individus malades et sains. Ces données nous ont permis d'isoler les serp

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Götzfried, Jessica Tanja Tamara [Verfasser], and Karl-Peter [Akademischer Betreuer] Hopfner. "Genetic, biochemical and preclinical studies on a tandem cluster of two human serpins: alpha-1-antitrypsin and serpina2 / Jessica Tanja Tamara Götzfried ; Betreuer: Karl-Peter Hopfner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1160876223/34.

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Souza, Lucas Rodrigo de. "Desenvolvimento de bibliotecas baseadas em serpinas para geração de inibidores de calicreínas teciduais humanas." reponame:Repositório Institucional da UFABC, 2017.

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Orientador: Prof. Dr. Luciano Puzer<br>Tese (doutorado) - Universidade Federal do ABC, Programa de Pós-Graduação em Biossistemas, 2017.<br>As calicreinas teciduais humanas (KLKs) compreendem uma familia de quinze serino proteases encontradas em uma diversidade de fluidos e tecidos biologicos. Estas enzimas sao identificadas como possuindo papel em diferentes doencas como Alzheimer, cancer, dermatite atopica, esclerose multipla, Parkinson, psoriase e outras. Existe, portanto, uma crescente demanda por inibidores especificos para cada uma das calicreinas e este e o objetivo do nosso grupo de pes

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Evans, Dyfed Ll. "The heparin activateable serpins." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385390.

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Aymonnier, Karen. "La protease Nexine-1, une cible prometteuse dans le traitement de l'hémophilie et son rôle dans les polynucléaires neutrophiles." Thesis, Sorbonne Paris Cité, 2019. http://www.theses.fr/2019USPCC049.

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L’hémophilie A est une maladie hémorragique rare caractérisée par un déficit du facteur de la coagulation VIII (FVIII). De nouvelles stratégies thérapeutiques ne reposant pas sur l’injection de FVIII se développent. Nous proposons une approche innovante qui consiste à cibler un anticoagulant naturel présent dans les plaquettes, la Protéase Nexine-1 (PN-1). La PN-1 est un inhibiteur puissant de la thrombine, enzyme clé de la coagulation. Bloquer la PN-1 favoriserait ainsi la génération de thrombine et donc la coagulation chez les patients hémophiles. Nous avons montré que bloquer la PN-1 amélio

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Книги з теми "SERPINH1"

Lucas, Alexandra, ed. Serpins. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8645-3.

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Macaryus, Sudartomo. Serpih-serpih pandangan Ki Hadjar Dewantara. Universitas Sarjanawiyata Tamansiswa bekerjasama dengan Penerbit Kepel Press, 2010.

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Kaswanti, Purwo Bambang, ed. Serpih-serpih telaah pasif bahasa Indonesia. Kanisius, 1989.

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Whisstock, James C. Biology of serpins. Elsevier, Acad. Press, 2011.

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Geiger, Margarethe, Felix Wahlmüller, and Margareta Furtmüller, eds. The Serpin Family. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22711-5.

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Church, Frank C., Dennis D. Cunningham, David Ginsburg, Maureane Hoffman, Stuart R. Stone, and Douglas M. Tollefsen, eds. Chemistry and Biology of Serpins. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5391-5.

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C, Church Frank, and International Symposium on the Chemistry and Biology of Serpins (1996 : Chapel Hill, N.C.), eds. Chemistry and biology of serpins. Plenum Press, 1997.

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Gettins, Peter G. W. Serpins: Structure, function, and biology. R.G. Landes, 1996.

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Potempa, Jan. Struktura, funkcja i ewolucja serpin. Nakł. Uniwersytetu Jagiellońskiego, 1993.

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Barnes, Ruth C. Identification and characterisation of a novel human serpin gene: Leupin. University College Dublin, 1998.

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Частини книг з теми "SERPINH1"

Czekay, Ralf-Peter, Tessa M. Simone, and Paul J. Higgins. "SerpinE1." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101828.

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Czekay, Ralf Peter, Tessa M. Simone, and Paul J. Higgins. "SerpinE1." In Encyclopedia of Signaling Molecules. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101828-1.

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Travis, James. "Serpins." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5391-5_1.

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Stone, Stuart R., James C. Whisstock, Stephen P. Bottomley, and Paul C. R. Hopkins. "Serpins." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5391-5_2.

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Johnson, Tierra A., Marguerite S. Buzza, Ekemini A. U. Riley, and Toni M. Antalis. "Plasminogen Activator Inhibitor Type-2 (PAI-2)/SerpinB2: A Unique Multifunctional Serpin." In The Serpin Family. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22711-5_8.

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Metze, Dieter, Tam Nguyen, Birgit Haack, et al. "Deficiency of AT-III SERPINC1." In Encyclopedia of Molecular Mechanisms of Disease. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6346.

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Cierniewski, Czeslaw S., and Joanna Boncela. "Serpins in Angiogenesis." In Angiogenesis and Vascularisation. Springer Vienna, 2013. http://dx.doi.org/10.1007/978-3-7091-1428-5_5.

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Cohen, Maja, Thomas H. Roberts, and Robert Fluhr. "Serpins in Plants." In The Serpin Family. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22711-5_2.

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Alberdi, Elena, and S. Patricia Becerra. "Inflammation and Noninhibitor Serpins." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5391-5_25.

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Luke, Cliff J., Mark T. Miedel, Linda P. O’Reilly, et al. "Serpins in Caenorhabditis elegans." In The Serpin Family. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22711-5_15.

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Тези доповідей конференцій з теми "SERPINH1"

Karelina, K. V., R. B. Bayandin, and V. A. . Ternovoi. "PRODUCTION OF A FRAGMENT OF RECOMBINANT TICK PROTECTIVE ANTIGEN SERPIN IPIS-1, RCL-LOOP DOMAIN, OF IXODES PERSULCATUS TICKS." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-87.

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Infections carried by ticks cause significant damage to livestock production, infections lead to loss of productivity, weakened immunity, allergic reactions, weight loss, and in severe cases death. When bitten, ticks produce a number of proteins — tick defense antigens — that facilitate the tick’s feeding on the host and thus facilitate the transmission of the infections they carry. Some of the tick protective antigens are serpins, a promising target for animal immunization and infection control. In studies, serpins from tick saliva have been shown to interact with host proteins while reducing

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Pannekoek, H., M. Linders, J. Keijer, H. Veerman, H. Van Heerikhuizen, and D. J. Loskutoff. "THE STRUCTURE OF THE HUMAN ENDOTHELIAL PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) GENE: NON-RANDOM POSITIONING OF INTRONS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644767.

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The endothelium plays a crucial role in the regulation of the fibrinolytic process, since it synthesizes and secretes tissue-type plasminogen activator (t-PA) as well as the fast-acting plasminogen activator inhibitor (PAI-1). Molecular cloning of full-length PAI-1 cDNA, employing a human endothelial cDNA expression library, and a subsequent determination of the complete nucleotide sequence, allowed a prediction of the amino-acid sequence of the PAI-1 glycoprotein. It was observed that the amino-acid sequence is significantly homologous to those of members of the serine protease inhibitor ("Se

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Ny, T., L. Hansson, and B. Åstedt. "ISOLATION OF cDNA FOR TYPE-2 PLASMINOGEN ACTIVATOR INHIBITOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642855.

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The placental type plasminogen activator inhibitor (PAI-2) has been purified from extracts of human placenta and from a histiocytic lymphoma cell line. It is mainly an uPA inhibitor but it also inhibits the two-chain form of tPA.In order to determine the factors regulating PAI-2 gene expression and thereby clarify the physiological role of PAI-2 we have undertaken the molecular cloning of PAI-2 cDNA. A λgt11 expression library prepared from placental mRNA, was screened, immunologically using a monoclonal antibody probe developed against PAI-2 purified from human placenta. When 1.7×105 recombin

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Strandberg, L., D. Lawrence, and T. Ny. "ISOLATION OF THE GENOMIC REGION CODING FOR TYPE-1 PLASMINOGEN ACTIVATOR INHIBITOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644439.

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The type-1 Plasminogen Activator Inhibitor (PAI-1) has recently been identified as a member of the Serine Protease Inhibitor family (SERPINS). This family of proteins contain many serine protease inhibitors but also functionally unrelated proteins like ovalbumin and anginotensinogen. PAI-1 inhibits both u-PA and t-PA and might therefore be an important regulator of the fibrinolytic system.In order to study the evolution of the Serpin family as well as PAI-1 gene expression we have isolated the genomic region carrying the PAI-1 gene. A cDNA sequence for PAI-1 was used as probe to screen a human

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Linja-Aho, Anna, Witold Mazur, Tuula Toljamo, et al. "Association Of SerpinA1 With Smoking And COPD." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4362.

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Niemietz, C., S. Guttmann, V. Sandfort, and H. Schmidt. "SERPINA1 levels dictate TTR expression in HepG2 cells." In 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0038-1677092.

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Niemietz, C., and H. Schmidt. "Inverse Expression von SERPINA1 und TTR bei TTR Amyloidose." In Viszeralmedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1695237.

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Ferrarotti, I., M. Zorzetto, I. Campo, et al. "SERPINA1 Gene Informative SNPs To Predict AAT Plasma Level." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a3504.

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Rufino, M. C., T. Bartholo, A. P. Viana, B. Chaves, V. D´Elia, and C. Costa. "SERPINA1 Gene Polymorphism: Analysis of Patients Over 2 Years." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a3785.

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Vlasov, A. P., V. A. Trofimov, S. S. Al-Kubaysi, et al. "Personalized approach in optimizing the treatment of acute pancreatitis." In VIII Vserossijskaja konferencija s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka». Publishing center of Ulyanovsk State University, 2021. http://dx.doi.org/10.34014/mpphe.2021-60-62.

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In order to determine the effectiveness of the use of remaxol based on a personalized approach in patients with acute pancreatitis, based on the establishment of gene polymorphism of integrin beta-3 (T1565C, ITGB3), integrin alpha-2 (C807T, ITGA2), fibrinogen (G(-455)A, FGB) and plasminogen activator inhibitor (5G(-675)4G, SERPINE1), a study of 84 patients with acute pancreatitis of varying severity was conducted. As a result of the study, it was proved that in order to increase the effectiveness of treatment of patients with severe acute pancreatitis upon admission, in addition to clinical, l

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