Готові списки джерел за темами / Single-Cell Selectivity

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Добірка наукової літератури з теми "Single-Cell Selectivity"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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Статті в журналах з теми "Single-Cell Selectivity"

Wertz, Adrian, Stuart Trenholm, Keisuke Yonehara, et al. "Single-cell–initiated monosynaptic tracing reveals layer-specific cortical network modules." Science 349, no. 6243 (2015): 70–74. http://dx.doi.org/10.1126/science.aab1687.

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Individual cortical neurons can selectively respond to specific environmental features, such as visual motion or faces. How this relates to the selectivity of the presynaptic network across cortical layers remains unclear. We used single-cell–initiated, monosynaptically restricted retrograde transsynaptic tracing with rabies viruses expressing GCaMP6s to image, in vivo, the visual motion–evoked activity of individual layer 2/3 pyramidal neurons and their presynaptic networks across layers in mouse primary visual cortex. Neurons within each layer exhibited similar motion direction preferences,

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Mao, Zhu, Zhuo Liu, Jin Yang, Xiaoxia Han, Bing Zhao, and Chun Zhao. "In situ semi-quantitative assessment of single-cell viability by resonance Raman spectroscopy." Chemical Communications 54, no. 52 (2018): 7135–38. http://dx.doi.org/10.1039/c8cc01336e.

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We developed a novel method for quantifying single-cell viability with high selectivity by resonance Raman scattering. This powerful tool will allow researchers to study cellular metabolism at the level of a single cell.

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Różycki, Bartosz, and Thomas R. Weikl. "Cooperative Stabilization of Close-Contact Zones Leads to Sensitivity and Selectivity in T-Cell Recognition." Cells 10, no. 5 (2021): 1023. http://dx.doi.org/10.3390/cells10051023.

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T cells are sensitive to 1 to 10 foreign-peptide-MHC complexes among a vast majority of self-peptide-MHC complexes, and discriminate selectively between peptide-MHC complexes that differ not much in their binding affinity to T-cell receptors (TCRs). Quantitative models that aim to explain this sensitivity and selectivity largely focus on single TCR/peptide-MHC complexes, but T cell adhesion involves a multitude of different complexes. In this article, we demonstrate in a three-dimensional computational model of T-cell adhesion that the cooperative stabilization of close-contact zones is sensit

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Decramer, Thomas, Elsie Premereur, Mats Uytterhoeven, et al. "Single-cell selectivity and functional architecture of human lateral occipital complex." PLOS Biology 17, no. 9 (2019): e3000280. http://dx.doi.org/10.1371/journal.pbio.3000280.

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Pasquier, Jennifer, Damien Rioult, Nadine Abu-Kaoud, et al. "P-Glycoprotein-Activity Measurements in Multidrug Resistant Cell Lines: Single-Cell versus Single-Well Population Fluorescence Methods." BioMed Research International 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/676845.

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Background. P-gp expression has been linked to the efflux of chemotherapeutic drugs in human cancers leading to multidrug resistance. Fluorescence techniques have been widely applied to measure the P-gp activity. In this paper, there is a comparison between the advantages of two fluorescence approaches of commonly available and affordable instruments: the microplate reader (MPR) and the flow cytometer to detect the P-gp efflux activity using calcein-AM.Results. The selectivity, sensibility, and reproducibility of the two methods have been defined. Our results showed that the MPR is more powerf

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Sawamura, Hiromasa, Guy A. Orban, and Rufin Vogels. "Selectivity of Neuronal Adaptation Does Not Match Response Selectivity: A Single-Cell Study of the fMRI Adaptation Paradigm." Neuron 49, no. 2 (2006): 307–18. http://dx.doi.org/10.1016/j.neuron.2005.11.028.

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Decramer, Thomas, Elsie Premereur, Mats Uytterhoeven, et al. "Correction: Single-cell selectivity and functional architecture of human lateral occipital complex." PLOS Biology 17, no. 12 (2019): e3000588. http://dx.doi.org/10.1371/journal.pbio.3000588.

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Li, Jin, Lilin Wang, Pasi A. Jänne, and G. Mike Makrigiorgos. "Coamplification at Lower Denaturation Temperature-PCR Increases Mutation-Detection Selectivity of TaqMan-Based Real-Time PCR." Clinical Chemistry 55, no. 4 (2009): 748–56. http://dx.doi.org/10.1373/clinchem.2008.113381.

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Abstract Background: DNA genotyping with mutation-specific TaqMan® probes (Applied Biosystems) is broadly used in detection of single-nucleotide polymorphisms but is less so for somatic mutations because of its limited selectivity for low-level mutations. We recently described coamplification at lower denaturation temperature-PCR (COLD-PCR), a method that amplifies minority alleles selectively from mixtures of wild-type and mutation-containing sequences during the PCR. We demonstrate that combining COLD-PCR with TaqMan technology provides TaqMan genotyping with the selectivity needed to detect

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Carrasco, Carlos J., Antonio Pastor, María del Mar Conejo, et al. "Synthesis, Characterization, and Preliminary In Vitro Anticancer Activity of Zinc Complexes Containing Amino Acid-Derived Imidazolium-Based Dicarboxylate Ligands." International Journal of Molecular Sciences 26, no. 7 (2025): 3202. https://doi.org/10.3390/ijms26073202.

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Coordination polymers containing zinc and imidazolium-based dicarboxylate ligands, [LR]−, were synthesized by reacting zinc acetate with HLR compounds, 1. The resulting complexes were characterized and structurally identified using single-crystal X-ray diffraction, revealing polymeric structures for the complexes [Zn(LR)2]n (R = Gly, 2a; βAla, 2b) and [Zn(LLeu)2(H2O)2]n (2c). In these structures, the [LR]− ligands adopt a bridging monodentate μ-κ1-O1,κ1-O3 coordination mode, resulting in distorted tetrahedral (2a, 2b) or octahedral (2c) geometries around the zinc center. When the synthesis was

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Higginson-Scott, Nathan, Kevin L. Otipoby, and Jo Viney. "PT101: A Treg selective agonist IL-2 mutein therapy for autoimmunity." Journal of Immunology 204, no. 1_Supplement (2020): 237.16. http://dx.doi.org/10.4049/jimmunol.204.supp.237.16.

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Abstract Regulatory T cells (Treg) play a critical role in immune homeostasis and are dysfunctional in many autoimmune diseases. Interleukin 2 (IL-2), via the heterotrimeric IL-2 receptor (CD25/CD122/CD132), drives the proliferation and function of Treg. CD25 loss-of-function in mice is associated with Treg deficiency and widespread autoimmunity. Low dose IL-2 expands Tregs and is being evaluated therapeutically, however it has a narrow selectivity window over conventional T cells and Natural Killer cells which is dose limiting. To enhance IL-2 selectivity for activating and expanding Treg, mu

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Більше джерел

Дисертації з теми "Single-Cell Selectivity"

Moffat, Jeffrey C. "Properties of Conductance and Inhibition of Proton Channels: M2 from Influenza A Virus and Fo from Escherichia coli ATP Synthase." BYU ScholarsArchive, 2006. https://scholarsarchive.byu.edu/etd/479.

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Proton channels are essential for many of the processes of life. The influenza A viral protein M2 is responsible for sensing the conditions necessary for viral RNA release. The proton-translocating FoF1 ATPase (ATP synthase) uses a proton gradient to drive adenosine triphosphate (ATP) synthesis. We have directly measured proton uptake in vesicles containing reconstituted M2 or FO by monitoring external pH after addition of valinomycin to vesicles with 100-fold diluted external [K+]. This proton flux assay was utilized to quantify proton flux through single M2 and Fo channels. Contrary to previ

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Basri, A. M., Rianne M. Lord, Simon J. Allison, et al. "Bis-Picolinamide ruthenium (III) dihalide complexes: dichloride to diiodide exchange generates single trans isomers with high potency and cancer cell selectivity." 2017. http://hdl.handle.net/10454/11550.

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Yes<br>A library of new bis-picolinamide ruthenium(III) dihalide complexes of the type RuX2L2 (X = Cl or I and L = picolinamide) have been synthesised and characterised. They exhibit different picolinamide ligand binding modes, whereby one ligand is bound (N,N) and the other bound (N,O). Structural studies reveal a mixture of cis and trans isomers for the RuCl2L2 complexes but upon a halide exchange reaction to RuI2L2, only single trans isomers are present. High cytotoxic activity against human cancer cell lines was observed, with potencies for some complexes similar to or better than cisplati

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Barker, Megan. "Structural Investigation of Processing α-Glucosidase I from Saccharomyces cerevisiae". Thesis, 2010. http://hdl.handle.net/1807/32660.

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N-glycosylation is the most common eukaryotic post-translational modification, impacting on protein stability, folding, and protein-protein interactions. More broadly, N-glycans play biological roles in reaction kinetics modulation, intracellular protein trafficking, and cell-cell communications. The machinery responsible for the initial stages of N-glycan assembly and processing is found on the membrane of the endoplasmic reticulum. Following N-glycan transfer to a nascent glycoprotein, the enzyme Processing α-Glucosidase I (GluI) catalyzes the selective removal of the terminal glucose re

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Книги з теми "Single-Cell Selectivity"

Orrit, Michel. Single-molecule spectroscopy. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198768609.003.0006.

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This chapter gives an overview of the main optical methods used to detect and study single molecules and other small objects (nano-objects). Much of the work so far has exploited the excellent sensitivity and selectivity of fluorescence, but several new techniques, mostly based on nonlinear optics, have recently reached the single-molecule or single-nanoparticle regime. The chapter briefly discusses some results with reference to published reviews. Single-molecule techniques have now been incorporated into the arsenal of the physico-chemist and the cell biologist. However, the recent developme

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Частини книг з теми "Single-Cell Selectivity"

Hellmeier, Joschka, René Platzer, Johannes B. Huppa, and Eva Sevcsik. "A DNA Origami-Based Biointerface to Interrogate the Spatial Requirements for Sensitized T-Cell Antigen Recognition." In The Immune Synapse. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3135-5_18.

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AbstractWhen T cells scan the surface of antigen-presenting cells (APCs), they can detect the presence of just a few antigenic peptide/MHC complexes (pMHCs), in some cases even a single agonist pMHC. These are typically vastly outnumbered by structurally similar yet non-stimulatory endogenous pMHCs. How T cells achieve this enormous sensitivity and selectivity is still not clear, in particular in view of the rather moderate (1–100 μM) affinity that T-cell receptors (TCRs) typically exert for antigenic pMHCs. Experimental approaches that enable the control and quantification of physical input p

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Malavena, Gerardo. "Modeling of GIDL–Assisted Erase in 3–D NAND Flash Memory Arrays and Its Employment in NOR Flash–Based Spiking Neural Networks." In Special Topics in Information Technology. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-85918-3_4.

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AbstractSince the very first introduction of three-dimensional (3–D) vertical-channel (VC) NAND Flash memory arrays, gate-induced drain leakage (GIDL) current has been suggested as a solution to increase the string channel potential to trigger the erase operation. Thanks to that erase scheme, the memory array can be built directly on the top of a $$n^+$$ n + plate, without requiring any p-doped region to contact the string channel and therefore allowing to simplify the manufacturing process and increase the array integration density. For those reasons, the understanding of the physical phenome

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Sgourakis, Nikolaos G., Pantelis G. Bagos, and Stavros J. Hamodrakas. "Computational Methods for the Prediction of GPCRs Coupling Selectivity." In Handbook of Research on Systems Biology Applications in Medicine. IGI Global, 2009. http://dx.doi.org/10.4018/978-1-60566-076-9.ch009.

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GPCRs comprise a wide and diverse class of eukaryotic transmembrane proteins with well-established pharmacological significance. As a consequence of recent genome projects, there is a wealth of information at the sequence level that lacks any functional annotation. These receptors, often quoted as orphan GPCRs, could potentially lead to novel drug targets. However, typical experiments that aim at elucidating their function are hampered by the lack of knowledge on their selective coupling partners at the interior of the cell, the G-proteins. Up-to-date, computational efforts to predict properti

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Leak, David J., Xudong Feng, and Emma A. C. Emanuelsson. "Enzyme Biotransformations and Reactors." In Chemical Processes for a Sustainable Future. The Royal Society of Chemistry, 2014. http://dx.doi.org/10.1039/bk9781849739757-00320.

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Enzyme-catalysed biotransformations, either using whole cells or free enzymes, are increasingly being exploited in industrial chemistry. They can offer remarkable reaction, stereo- and regio-selectivity, and work in benign aqueous systems. Some enzymes are remarkably robust, while others are relatively fragile, but may be stabilized by immobilization or used in whole cell systems. The use of purified (or partially purified) enzymes avoids the possibility of side reactions (of substrate or product), but incurs the additional cost of purification. This is why, historically, some of the most comm

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Singh, Soni, Parul Bhatt Kottiyal, Archana Rawat, and Neeraj Verma. "Microbial Biotransformation in Steroids Production." In Industrial Applications of Soil Microbes. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815079753124030015.

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Biocatalysis is also widely applicable for the enhancement of bioprocess productivity, selectivity of target reactions, and production of valuable chemicals, pharmaceutical ingredients, precursors, and key intermediates. The vast majority of such enzymes are of microbial origin and include dehydrogenases, oxygenases, hydrolases, transferases, and lyases. These enzymes may introduce minor molecule changes, such as the insertion of a hydroxyl or keto function or the saturation or desaturation of a complex cyclic structure. Microorganisms and cell suspension cultures of the plant are applied in b

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Varshney, Shruti, Abhishek Tiwari, and Rakhi Mishra. "RECENT UPDATES ON PROMISING TARGETS IN ANTICANCER ACTION: A REVIEW." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 7. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bapn7p1ch8.

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Cancer is a multifactorial disease that is characterized by the failure of the normal mechanism of cell regulation which consists of survival, proliferation, and differentiation of the cell. Traditional chemotherapeutical agents directly target the DNA of the cell while modern antiproliferative agents engage in targeting the proteins showing abnormal expression inside the cancer cells also known as molecular–targeted therapy. In comparison to molecular targeted therapy, traditional therapies are ineffective in the complete abolition of the cancer cells while targeted chemotherapy shows its eff

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Yin, Ling. "Gene Editing in ErbB/HER Family-Mediated Cancer Immunology." In Genome Editing - Recent Advances and Applications [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1008441.

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The ErbB/HER family has an essential role in tumor progression, proliferation, invasion, metastasis, and migration. ErbB/HER-targeted therapeutic agents have emerged as effective therapeutic options to achieve excellent clinical outcomes and boost cancer drug discovery by enhancing treatment efficacy, lowering drug resistance, and minimizing systemic toxicity. Furthermore, combination therapy targeting ErbB/HER family members, as well as hormonal therapy, chemotherapy, immunotherapy, and radiotherapy, also enhances therapeutic effects for cancer immunology. Zinc-finger nucleases (ZFNs), transc

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B.Levitan, Irwin, and Leonard K. Kaczmarek. "Ion Channels, Membrane Ion Currents, and the Action Potential." In The Neuron. Oxford University PressNew York, NY, 2001. http://dx.doi.org/10.1093/oso/9780195145236.003.0006.

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Abstract A great deal of what we know about ion channels, including information about selectivity and gating of different types of channels, was already understood long before single channel recording and the application of molecular and structural approaches revolutionized the field. This understanding developed because, for more than 60 years, the voltage clamp invented by K. C. Cole allowed us to record the macroscopic membrane current in some cells. As we discussed in Chapter 4, the macroscopic current is the combined current flowing simultaneously through all the active ion channels in th

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Gurney, Alison M. "Photolabile calcium buffers to selectively activate calciumdependent processes." In Cellular Neurobiology. Oxford University PressOxford, 1991. http://dx.doi.org/10.1093/oso/9780199631063.003.0009.

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Abstract Optical probes provide a particularly powerful means for manipulating the concentration of free calcium inside or outside neurons. Photosensitive calcium buffers are molecules that either release or sequester calcium upon irradiation with appropriate wavelengths. The experimental usefulness of these probes lies in the speed of the photochemical reactions, as well as the ease with which the intensity, duration, and area of activating light can be varied. Thus the light could be directed at a whole population of cells, or be focused into a spot small enough to irradiate a single cell or

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Wu, William, and Scott A. Small. "Dementia: visualizing the metabolic changes of early Alzheimer’s disease." In Clinical Applications of Functional Brain MRI. Oxford University PressOxford, 2007. http://dx.doi.org/10.1093/oso/9780198566298.003.0006.

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Abstract The pathological course of Alzheimer’s disease (AD) progresses slowly, taking years to cause cognitive disability, producing an often confusing array of histological and functional alterations in the brain. Despite notable inconsistencies, a consensus regarding the anatomy and physiology of AD has emerged by investigating brain tissue, both living and dead, in human patients and in mouse models of disease. Prospective neuropsychological studies have made the fundamental observation that AD begins in the hippocampal formation. The hippocampus itself is made up of anatomically distinct

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Тези доповідей конференцій з теми "Single-Cell Selectivity"

Whitney, Jon, Harry Dorn, Chris Rylander, Tom Campbell, David Geohegan, and Marissa Nichole Rylander. "Spatiotemporal Temperature and Cell Viability Measurement Following Laser Therapy in Combination With Carbon Nanohorns." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19619.

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Cancer remains one of the most deadly diseases today. Laser-induced photothermal therapy can provide a minimally invasive treatment alternative to surgical resection. The selectivity and effectiveness of laser therapy can be greatly enhanced when photoabsorbing nanoparticles such as nanoshells, single walled carbon nanotubes, multi-walled carbon nanotubes, or single wall carbon nanohorns (SWNHs) are introduced into the tissue. Prior studies have effectively used SWNHs combined with near infrared (NIR) laser light to target and destroy microbes [1]. We have previously reported increased tumor c

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Effertz, T., L. Becker, D. Beutner, and AJ Ricci. "Cell membrane lipids affect the mechano-electrical transduction channel. PIP2 (phosphatidylinositol-4,5-bisphosphat) specifically modulating single channel conductance and ion selectivity." In Abstract- und Posterband – 90. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Digitalisierung in der HNO-Heilkunde. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1686365.

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Schiller, Peter H. "ON and OFF channels of the visual system." In OSA Annual Meeting. Optica Publishing Group, 1990. http://dx.doi.org/10.1364/oam.1990.thf2.

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The receptors of the mammalian retina, which all hyperpolarize to light, make signconserving synapses with OFF bipolars and sign-inverting synapses with ON bipolars. Several hypotheses have been generated to explain this arrangement. To test them we applied the neurotransmitter agonist 2-amino-4-phosphonobutyrate (APB) to the retina, which selectively blocks the ON bipolars. Two kinds of experiments were carried out: In one, we examined the visual responses of single cells while reversibly inactivating the ON channel with APB. In the other, we assessed the visual capacities of monkeys before a

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Harmošová, Michaela, Martin Kello, Mária Vilková, Erika Samoľová, and Ivan Potočňák. "Synthesis, structure and anticancer activity of Zr(IV) complexes with Schiff bases derived from 8-hydroxyquinoline." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.439h.

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The Schiff base 2-{[(2-hydroxyphenyl)imino]methyl}quinolin-8-ol (HLH) and its 5,7-dibromo- (HBrLH) and 5,7-diiodo-derivatives (HILH), which were prepared by multi-step organic synthesis, were used to synthesize [Zr(L)2]·2DMF (1), [Zr(BrL)2]·DMF (2), and [Zr(IL)2]·2DMF (3) complexes. The prepared products were characterized by elemental analysis, IR and NMR spectroscopy, which also monitored the stability of the prepared substances in DMSO, and in the case of HBrLH, HILH and 3, also by single crystal X-ray structural analysis. In the complex 3, two IL ligands are tetradentately bound to the cen

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Covey, Todd M., Santosh Putta, Michael Gulrajani, Aileen C. Cohen, and Alessandra Cesano. "Abstract B182: Single cell network profiling (SCNP) by flow cytometry as a tool to measure potency and selectivity of JAK/STAT inhibitors in PBMC and whole blood discrete cell subsets." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 15-19, 2009; Boston, MA. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/1535-7163.targ-09-b182.

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Whitney, Jon, William Carswell, Matthew DeWitt, John Robertson, Chris Rylander, and Marissa Nichole Rylander. "Spatial Measurement of Viability in Tissue Phantoms and Ex Vivo Bladder Tissue in Response to Photothermal Therapy and Single Walled Carbon Nanohorns." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80903.

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Cancer is one of the most deadly diseases and leading cause of death. Laser based photothermal therapy can provide a minimally invasive alternative to surgical resection. The selectivity and effectiveness of laser therapy can be greatly enhanced when photoabsorbing nanoparticles such as nanoshells, single walled carbon nanotubes, multi-walled carbon nanotubes, or single wall carbon nanohorns (SWNHs) are introduced into the tissue[1]. Quantitative methods for measuring tumor response to nanoparticle enhanced laser therapies are critical for determining appropriate laser parameters and nanoparti

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Stanton, Alan C., and Daniel B. Oh. "In situ diode laser diagnostics of a plasma etching reactor." In OSA Annual Meeting. Optica Publishing Group, 1992. http://dx.doi.org/10.1364/oam.1992.thw5.

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A major objective of the microelectronics industry is to perfect methods for controlling dimensional accuracy during plasma etching of submicrometer features in wafer substrates. Optical sensors as monitors of gas phase etch chemistry are attractive because they offer the potential of nonintrusive in situ measurements for use as real time inputs to process control. In this study, lead salt infrared diode lasers were used to measure CF4 feed gas dissociation, neutral CF2 reactive intermediates, and CF2O etch products in fluorocarbon-based plasmas used for etching of silicon and silicon dioxide.

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Wang, Kang, Pingying Zeng, and Jeongmin Ahn. "An Electricity and Value-Added Gases Co-Generation via Solid Oxide Fuel Cells." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-62353.

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In this study, an electricity and value-added chemicals cogeneration system using methane-fueled single chamber solid oxide fuel cells (SC-SOFCs) was successfully developed and investigated. The SC-SOFCs, which operated on methane/oxygen gas mixture with a ratio of 2:1, achieved an open-circuit voltage of 1.0 V and a maximum peak power density of ∼ 840 mW.cm-2 at 700 °C. By passing the exhaust gas of the fuel cell through a Ru/Al2O3 catalyst at 700 °C, the synthesis gas is obtained with a methane conversion of higher than 95%, while CO and H2 selectivity is higher than 92%. This study provides

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Potočňák, Ivan, Miroslava Litecká, Jitka Prachařová, Monika Hreusová, and Jana Kašpárková. "Anticancer gallium(III) complexes with halogen- and nitroderivatives of 8- hydroxyquinoline." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.451p.

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Six gallium(III) complexes with halogen- or nitroderivatives of 8-hydroxyquinoline, [Ga(ClQ)3] (1), [Ga(BrQ)3] (2), [Ga(dIQ)3] (3), [Ga(CQ)3] (4), [Ga(NQ)3] (5) and [Ga(ClNQ)3]·MeOH were prepared as possible anticancer drugs (HClQ = 5-chloro-8-hydroxyquinoline, HBrQ = 7-bromo-8-roxyquinoline, HdIQ = 5,7-diiodo-8-hydroxyquinoline, HCQ = 5-chloro-7-iodo-8-ydroxyquinoline, HNQ = 5-nitro-8-hydroxyquinoline and HClNQ = 5-chloro-7-nitro-8-hydroxyquinoline). X-ray single crystal structure analysis of [Ga(ClQ)3]·MeOH (1 – MeOH) and 5 showed that both complexes are molecular complexes with Ga(III) coor

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Tamaddoni, Nima, and Stephen A. Sarles. "Mechanotransduction of Multi-Hair Droplet Arrays." In ASME 2014 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/smasis2014-7551.

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Early embodiments of droplet interface bilayer (DIB)-based hair cell sensors demonstrated the capability of sensing discrete and continuous perturbations, including single flicks and constant airflow, respectively, of a hair structure that is held in close proximity to a single lipid membrane. In those studies, the use of a single bilayer formed between a pair of droplets provided the necessary environment for studying the physical mechanism of mechanotransduction of a membrane-based sensor as well as the sensitivity and directionality of the assembly. More recently, we showed that additional

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