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Добірка наукової літератури з теми "SSLS"

Автор: Grafiati

Опубліковано: 23 червня 2021

Оновлено: 11 лютого 2022

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Статті в журналах з теми "SSLS"

Al-Shangiti, Ali M., Claire E. Naylor, Sean P. Nair, David C. Briggs, Brian Henderson, and Benjamin M. Chain. "Structural Relationships and Cellular Tropism of Staphylococcal Superantigen-Like Proteins." Infection and Immunity 72, no. 7 (2004): 4261–70. http://dx.doi.org/10.1128/iai.72.7.4261-4270.2004.

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ABSTRACT The staphylococcal superantigen-like proteins (SSLs) are a family of polymorphic paralogs encoded in the Staphylococcus aureus genome whose function is unknown. The crystal structure of SSL7 was determined and compared to that of SSL5 and that of a classical superantigen, streptococcal pyrogenic exotoxin. Although the overall architecture of the superantigen family is retained in both SSL7 and SSL5, there are significant differences in the structures which suggest that the characteristic major histocompatibility complex binding site of superantigens has been lost. To complement these data, the abilities of SSL7 and a closely related paralog, SSL9, to interact with cells of the immune system were investigated. In populations of human white blood cells, both SSLs interacted selectively with monocytes via specific saturable but separate binding sites, which led to rapid uptake of the SSLs. In addition, SSLs were rapidly taken up by dendritic cells, but not by macrophages, into the same endosomal compartment as dextran. The ability of these secreted proteins to target antigen-presenting cells may enhance a misplaced antibody response against the proteins, which may facilitate bacterial colonization rather than contribute to host protection. Like classical superantigens, therefore, SSLs may distract the host's immune system, but they may do so via entirely different molecular mechanisms.

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Koymans, Kirsten J., Oliver Goldmann, Christofer A. Q. Karlsson, et al. "The TLR2 Antagonist Staphylococcal Superantigen-Like Protein 3 Acts as a Virulence Factor to Promote Bacterial Pathogenicity in vivo." Journal of Innate Immunity 9, no. 6 (2017): 561–73. http://dx.doi.org/10.1159/000479100.

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Toll-like receptor (TLR) signaling is important in the initiation of immune responses and subsequent instigation of adaptive immunity. TLR2 recognizes bacterial lipoproteins and plays a central role in the host defense against bacterial infections, including those caused by Staphylococcus aureus. Many studies have demonstrated the importance of TLR2 in murine S. aureus infection. S. aureus evades TLR2 activation by secreting two proteins, staphylococcal superantigen-like protein 3 (SSL3) and 4 (SSL4). In this study, we demonstrate that antibodies against SSL3 and SSL4 are found in healthy individuals, indicating that humans are exposed to these proteins during S. aureus colonization or infection. To investigate the TLR2-antagonistic properties of SSL3 and SSL4, we compared the infection with wild-type and SSL3/4 knockout S. aureus strains in an intravenous murine infection model. Direct evaluation of the contribution of SSL3/4 to infection pathogenesis was hindered by the fact that the SSLs were not expressed in the murine system. To circumvent this limitation, an SSL3-overproducing strain (pLukM-SSL3) was generated, resulting in constitutive expression of SSL3. pLukM-SSL3 exhibited increased virulence compared to the parental strain in a murine model that was found to be TLR2 dependent. Altogether, these data indicate that SSL3 contributes to S. aureus virulence in vivo.

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Yokoyama, Ryosuke, Saotomo Itoh, Go Kamoshida, et al. "Staphylococcal Superantigen-Like Protein 3 Binds to the Toll-Like Receptor 2 Extracellular Domain and Inhibits Cytokine Production Induced by Staphylococcus aureus, Cell Wall Component, or Lipopeptides in Murine Macrophages." Infection and Immunity 80, no. 8 (2012): 2816–25. http://dx.doi.org/10.1128/iai.00399-12.

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ABSTRACTStaphylococcal superantigen-like proteins (SSLs) are a family of exoproteins sharing structural similarity with superantigens, but no superantigenic activity. Corresponding host target proteins or receptors against a portion of SSLs in the family have been identified. In this study, we show that SSL3 specifically binds to Toll-like receptor 2 (TLR2) and inhibits the stimulation of macrophages by TLR2 ligands. An approximately 100-kDa protein was recovered by using recombinant His-tagged SSL3-conjugated Sepharose from the lysate of porcine spleen, and the protein was identified as porcine TLR2 by peptide mass fingerprinting analysis. The SSL3-conjugated Sepharose recovered human and mouse TLR2 but not TLR4 from human neutrophils and mouse macrophage RAW 264.7 cells, as well as a recombinant TLR2 extracellular domain chimera protein. The production levels of interleukin 12 (IL-12) from mouse macrophages treated with heat-killedStaphylococcus aureusand of tumor necrosis factor alpha (TNF-α) from RAW 264.7 cells induced by peptidoglycan or lipopeptide TLR2 ligands were strongly suppressed in the presence of SSL3. The mutation of consensus sialic acid-containing glycan-binding residues in SSL3 did not abrogate the binding ability to TLR2 or inhibitory activity on TLR2, indicating that the interaction of SSL3 with TLR2 was independent of the sialic acid-containing glycan-binding residues. These findings demonstrate that SSL3 is able to bind the extracellular domain of TLR2 and interfere with TLR2 function. The present study provides a novel mechanism of SSL3 in immune evasion ofS. aureusvia interfering with its recognition by innate immune cells.

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Hermans, Stefan J., Heather M. Baker, Richard P. Sequeira, Ries J. Langley, Edward N. Baker, and John D. Fraser. "Structural and Functional Properties of Staphylococcal Superantigen-Like Protein 4." Infection and Immunity 80, no. 11 (2012): 4004–13. http://dx.doi.org/10.1128/iai.00764-12.

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ABSTRACTStaphylococcus aureusis a prevalent and significant human pathogen. Among the repertoire of virulence factors produced by this bacterium are the 14 staphylococcal superantigen-like (SSL) proteins. SSL protein 4 (SSL4) is one member of this family and contains a highly conserved carbohydrate binding site also found in SSL2, SSL3, SSL5, SSL6, and SSL11. Recombinant SSL4t, comprising amino acids 109 to 309 of Newman strain SSL4 (SSL4-Newman), has been shown to bind and be internalized by human granulocytes and macrophages in a sialic-acid (Sia)-dependent manner. SSL4tcan compete with itself for cell binding, indicating that binding is target specific. A 2.5-Å-resolution crystal structure of SSL4tcomplexed with sialyl Lewis X (sLex) [sLex-Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAc] revealed a similar binding site to SSL5 and SSL11. These data, along with data on SSL4tbinding to a glycan array and biosensor analysis of sLexand sialyllactosamine (sLacNac) binding are compared with those for SSL11. Although these proteins show great similarity in their carbohydrate binding sites, with a root mean square (RMS) difference between main chain atom positions of only 0.34 Å, these proteins differ in detail in their affinity for sLexand sLacNac, as well as their glycan preference. Together with cell binding data, this shows howS. aureusproduces multiple related proteins that target myeloid cells through specific sialyllactosamine-containing glycoproteins.

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Diogoul, Ndague, Patrice Brehmer, Yannick Perrot, et al. "Fine-scale vertical structure of sound-scattering layers over an east border upwelling system and its relationship to pelagic habitat characteristics." Ocean Science 16, no. 1 (2020): 65–81. http://dx.doi.org/10.5194/os-16-65-2020.

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Abstract. Understanding the relationship between sound-scattering layers (SSLs) and pelagic habitat characteristics is a substantial step to apprehend ecosystem dynamics. SSLs are detected on echo sounders representing aggregated marine pelagic organisms. In this study, SSL characteristics of zooplankton and micronekton were identified during an upwelling event in two contrasting areas of the Senegalese continental shelf. Here a cold upwelling-influenced inshore area was sharply separated by a strong thermal boundary from a deeper, warmer, stratified offshore area. Mean SSL thickness and SSL vertical depth increased with the shelf depth. The thickest and deepest SSLs were observed in the offshore part of the shelf. Hence, zooplankton and micronekton seem to occur more frequently in stratified water conditions rather than in fresh upwelled water. Diel vertical and horizontal migrations of SSLs were observed in the study area. Diel period and physicochemical water characteristics influenced SSL depth and SSL thickness. Although chlorophyll-a concentration insignificantly affected SSL characteristics, the peak of chlorophyll a was always located above or in the middle of the SSLs, regularly matching with the peak of SSL biomass. Such observations indicate trophic relationships, suggesting SSLs to be mainly composed of phytoplanktivorous zooplankton and micronekton. Despite local hypoxia, below 30 m depth, distribution patterns of SSLs indicate no vertical migration boundary. The results increase the understanding of the spatial organization of mid-trophic species and migration patterns of zooplankton and micronekton, and they will also improve dispersal models for organisms in upwelling regions.

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Zhou, You Ya, Hui Yan Zhou, Yan Dong Tang, et al. "Development of Soil Screening Levels for Contaminated Sites Assessment in Beijing." Applied Mechanics and Materials 209-211 (October 2012): 1100–1105. http://dx.doi.org/10.4028/www.scientific.net/amm.209-211.1100.

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The Risk Based Corrective Action (RBCA) Tool Kit for Chemical Releases was used to develop Soil Screening Levels (SSLs) for contaminated sites assessment in Beijing. A total 88 contaminants, including inorganic compounds, volatile organic compounds, semi-volatile organic compounds, pesticides, polybrominated biphenyls and others, were identified as the priority compounds of concern, and a range of exposure parameters, toxicological data and site factors based on the environmental monitoring data from several contaminated sites in Beijing, were used as model inputs to derive SSLs. The proposed SSLs were evaluated and validated by comparing with corresponding values in some other countries/regions. The present study has an important guiding significance for the development of risk-based SSLs in other provinces/cities of China.

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Vishnu Prasanth, P., S. Sridharan, Y. Bhavani Kumar, and D. Narayana Rao. "Lidar observations of sporadic Na layers over Gadanki (13.5° N, 79.2° E)." Annales Geophysicae 25, no. 8 (2007): 1759–66. http://dx.doi.org/10.5194/angeo-25-1759-2007.

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Abstract. We studied the characteristics of sporadic sodium layers (SSLs) observed with the sodium (Na) resonance scattering lidar at Gadanki (13.5° N, 79.2° E). The SSLs were observed on a total of 63 occasions during 464 h of Na lidar observations from January 2005 to February 2006. The observations showed that one SSL event occurred, on average, every 7 h. The most prominent sporadic layer, which formed on 12 February 2005, exhibited a peak density of 60 722 Na atoms/cm³ around 92 km and it was nearly twice the peak density reported from elsewhere using ground-based observations. In general, the SSLs exhibited the following characteristics: (1) they developed at heights between 88 and 98 km with an average height around 94 km; (2) maximum density occurred during the early morning hours between 02:00 and 05:00 IST; (3) the ratio of the maximum peak Na density to the average density was normally around 3 to 5 and it exceeded even 10 in some cases; (4) the events lasted from a few minutes to several hours. The formation period of the SSLs was longer compared to the decay period of the SSLs. Most of the SSL events showed downward motions.

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Macarie, Melania, Simona Bataga, Simona Mocan, et al. "Correlation of Metabolic Risk Factors with Sessile Serrated Lesions." Journal of Gastrointestinal and Liver Diseases 29, no. 2 (2020): 175–79. http://dx.doi.org/10.15403/jgld-507.

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Background and Aims: The importance of sessile serrated lesions (SSLs) in the pathogenesis of colorectal carcinoma has been recently established. These are supposed to cause the so-called “interval cancer”, having a rapidly progressive growth and being difficult to detect and to obtain an endoscopic complete resection. We aimed to establish the most important metabolic risk factors for sessile serrated lesions. Methods: We performed a retrospective case-control study, on a series of 2918 consecutive patients who underwent colonoscopy in Gastroenterology and Endoscopy Unit, County Clinical Emergency Hospital, Târgu-Mureș, Romania between 1 st of January 2015-31 th of December 2017. In order to evaluate the metabolic risk factors for polyps’ development, enrolled participants were stratified in two groups, a study group, 33 patients with SSLs lesions, and a control group, 138 patients with adenomatous polyps, selected by systematic sampling for age and anatomical site. Independent variables investigated were: gender, smoking, alcohol consumption, obesity, arterial hypertension, diabetes, hypercholesterolemia, hypertriglyceridemia, hyperuricemia, nonalcoholic liver disease. Results: For SSLs the most common encountered localization was the right colon in 30.55% of cases. By comparative bivariate analysis between SSLs group and control group, it was observed that hypertension (p=0.03, OR 2.33, 95 %CI 1.03-5.24), obesity (p=0.03, OR 2.61, 95 %CI 1.08-6.30), hyperuricemia (p=0.04, OR 2.72, 95 %CI 1.28-7.55), high cholesterol (p=0.002, OR 3.42; 95 %CI 1.48-7.87), and high triglycerides level (p=0.0006, OR 5.75; 95 %CI 1.92-17.2) were statistically associated with SSLs development. By multivariate analysis hypertension and hypertriglyceridemia retained statistical significance. Conclusions: Our study showed that the highest prevalence of SSLs was in the right colon and hypertension and increased triglycerides levels were associated with the risk of SSLs development. These risk factors are easy to detect in clinical practice and may help identifying groups with high risk for colorectal cancer, where screening is recommended.

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Yang, S. L., R. Sandven, and L. Grande. "Steady-state lines of sand–silt mixtures." Canadian Geotechnical Journal 43, no. 11 (2006): 1213–19. http://dx.doi.org/10.1139/t06-069.

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The steady-state lines (SSLs) for sand–silt mixtures with various fines contents (0%, 5%, 10%, 15%, 20%, 30%, 50%, 70%, and 94%) were studied. It was indicated that the location of the SSL in the e–p′ space is different for each mixture, but the SSLs are parallel. In the e – ln p′ plot, the SSLs are similar for the mixtures with a fines content of less than the transitional fines content (TFC) when tested under drained and undrained conditions and the intergranular and interfine void ratios are used. The data diverge when the fines contents are equal to or greater than the TFC, even though the interfine void ratios are used. The results of the tests conducted under drained and undrained conditions produced a unique SSL in the p′–q space for each material. Different SSLs in the p′–q space were observed for the studied materials, and the friction angle at steady state varied in the range of 37.3°–42.2°. The study showed that the SSLs can be represented by one line in tests under drained conditions if the fines contents are less (0%–30%) than the TFC and the corrected intergranular void ratios are used. The lines can also be represented by one line for sand–silt mixtures with high fines contents (50%–94%) if the corrected interfine void ratios are used instead of void ratios. Key words: steady-state line, sand–silt mixtures, transitional fines content, drained and undrained triaxial tests.

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Li, Jie, Hiroaki Okamoto, Chunyue Yin, et al. "Proteomic characterization of primary diffuse large B-cell lymphomas in the central nervous system." Journal of Neurosurgery 109, no. 3 (2008): 536–46. http://dx.doi.org/10.3171/jns/2008/109/9/0536.

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Object The lack of primary lymphoid tissue within the central nervous system (CNS) confounds our understanding of the pathogenesis of primary CNS lymphomas (PCNSLs). Comparing the protein expression of PCNSLs and sporadic systemic lymphomas (SSLs) provides a useful strategy for identifying a molecular signature that characterizes disease-associated features and provides information regarding tumor initiation and progression. Methods Seven diffuse large B-cell PCNSLs were selected to undergo 2D gel electrophoresis, and profiled proteomes from these PCNSLs were compared with those from 7 diffuse large B-cell SSLs. Distinguishing proteins were sequenced using mass spectrometry. Results Two-dimensional gel electrophoresis identified an average of 706 proteins from each specimen. Computerized gel analysis and manual reconfirmation revealed a 96% similarity in the proteomes of PCNSLs and SSLs. Comparative analysis identified 9 proteins significantly overexpressed (p < 0.05) and 16 proteins downregulated in PCNSLs. The proteomic findings were further validated using Western blot and immunohistochemical staining. Conclusions The similarities in proteomic patterns between PCNSLs and SSLs suggest that these tumor types share structural similarities, acquired during differentiation. The ultimate fate of lymphomatous cells (CNS vs systemic) may be related to differentially expressed proteins, which function in homing and host processing. Elucidating the roles of these differentially expressed proteins will prove valuable in understanding the pathogenesis of PCNSL.

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Більше джерел

Дисертації з теми "SSLS"

Portugal-Nunes, Diogo João. "Bioethanol production from SSLs: S. stipitis vs S. cerevisiae." Master's thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/11279.

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Mestrado em Biotecnologia - Biotecnologia Industrial e Ambiental O objectivo desta dissertação foi a comparação da produção de bioetanol de 2ª geração por Scheffersomyces stipitis (em suspensão e imobilizada) e por duas estirpes industriais de Saccharomyces cerevisiae. Os substratos utilizados para a realização das fermentações foram os Licores de Cozimento ao Sulfito Ácido (SSLs) provenientes de madeira de resinosas (HSSL) e de madeiras de folhosas (SSSL – Domsjö hydrolysate). O HSSL e o SSSL são sub-produtos da indústria de pastas de papel, resultando do processo de cozimento ao sulfito com magnésio e sódio, respetivamente. Além de lenhosulfonatos, estes SSLs contêm monossacarídeos, destacando-se a glucose, xilose e manose. O ácido acético, composto inibidor da fermentação alcoólica por leveduras, também está presente em concentrações relativamente elevadas (≥ 5.0 g . L-1). O HSSL foi pré-tratado físico-quimicamente e submetido a uma remoção biológica de inibidores com P. variotii, enquanto o Domsjö hydrolysate foi utilizado sem qualquer tratamento. S. stipitis e S. cerevisiae são leveduras extensamente estudadas devido à sua capacidade de fermentação de pentoses e hexoses, respetivamente. Num estágio prévio às fermentações dos SSLs, as leveduras foram pré-adaptadas em 60% HSSL ou 40% SSSL. Os máximos de rendimento (0.440 g etanol . g açúcares-1) e produtividade em etanol (0.885 g etanol . L-1 . h-1) foram obtidos nas fermentações com S. cerevisiae TMB 3500 em SSSL, sendo estas as variáveis com maior potencial para aplicação industrial. Embora a cultura suspensa de S. stipitis tenha resultado numa menor produtividade (0.010 g etanol . L-1 . h-1), a optimização do fornecimento de oxigénio ao biorreator deverá conduzir ao aumento da produtividade volumétrica em etanol. A imobilização celular e o controlo do pH em 5.5 nas fermentações com S. stipitis melhoraram a eficiência fermentativa ao aumentarem a produção de etanol em 1.3 e 1.6 vezes, respetivamente. Quando aplicadas simultaneamente, estas duas condições aumentaram o rendimento em etanol 2.2 vezes, sugerindo que (i) a imobilização numa matriz de alginato de cálcio protegeu a levedura dos inibidores químicos e que (ii) o controlo de pH em 5.5 foi determinante para a produção de etanol a partir de HSSL biologicamente pré-tratado. Os resultados comprovam que ambos os SSLs são potenciais substratos para a produção de bioetanol de 2ª geração usando S. stipitis ou S. cerevisiae, sob o conceito de biorefinaria. The aim of this work was the comparison of second-generation bioethanol production by Scheffersomyces stipitis (free-culture and immobilized) and two Saccharomyces cerevisiae industrial strains, using Hardwood Spent Sulphite Liquor (HSSL) or Domsjö hydrolysate (SSSL) as substrate. HSSL and SSSL are side products of pulp and paper industry, from magnesium and sodium-based acidic sulphite pulping, respectively. Besides sulphonated lignin, SSLs contain fermentable sugars, mainly glucose, xylose and mannose. Acetic acid, a known inhibitor of ethanol fermentation by yeasts, is also present in a relatively high content (≥ 5.0 g . L-1). HSSL was previously physico-chemically pretreated and bio-detoxified with P. variotii, whereas SSSL was used without any treatment. S. stipitis and S. cerevisiae are the most widely studied pentose and hexose-fermenting yeasts, respectively. Before fermentations in SSLs, all yeast strains were pre-adapted by growing them in 60% HSSL or 40% SSSL. The highest maximum ethanol yield (0.440 g ethanol . g sugars-1) and productivity (0.885 g ethanol . L-1 . h-1) were obtained using S. cerevisiae TMB 3500 and SSSL. Suspended S. stipitis achieved a lower ethanol productivity (0.010 g ethanol . L-1 . h-1) but further optimization on the supplied oxygen in the fermentor might lead to higher ethanol productivity. Immobilization and pH control at 5.5 on S. stipitis fermentations improved the fermentation efficiency, increasing up the ethanol production by 1.3-fold and 1.6-fold, respectively. When applied simultaneously, these two conditions increased the ethanol yield 2.2-fold, suggesting that (i) immobilization with a calcium-alginate matrix protected the yeast from the inhibitory compounds and (ii) the controlled pH at 5.5 was essential for ethanol production from bio-detoxified HSSL. Results showed that both SSLs are potential substrates for the production of 2nd generation bioethanol by S. stipitis or S. cerevisiae, under the biorefinery concept.

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Kejser, Katrine. "“Pop a titty for the boys” -A qualitative study of negative communication towards femalestreamers on Twitch." Thesis, Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-92543.

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The development of technology has created many platforms for entertainment, participatorycommunities and socialization online. One of the largest current platforms for live streamingis Twitch.tv with a focus on gaming and eSports. This is a male-dominated field wherewomen often face harassment and a non-welcoming community. This paper is a qualitativestudy of the negative communication towards female streamers on Twitch with a focus onthe context in which said communication takes place. The aim of the study is to understandthe circumstances in which negative communication occurs and how it changes dependingon context. The study takes a qualitative approach and analyses the content of six streamsfrom five different channels, as well the negative communication in their chat room. Theresults show that negative communication varies depending on the content as well as thenature of the community built around the channel.

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Veselovský, Matej. "Vytvoření monitorovacího a profilovacího řešení nad BI systémem." Master's thesis, Vysoké učení technické v Brně. Fakulta podnikatelská, 2017. http://www.nusl.cz/ntk/nusl-318361.

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This master’s thesis focuses on monitoring and profiling multidimensional database and reports. The project was created in MS SSIS to this purpose and it contains 4 ETL packages. The thesis is divided into three main sections. First section consists of theoretical background needed to accomplish the goal. In second section there is analysis of the company for which is the solution created and in the third part of the thesis there is described the proposal and it’s solution. Proposal of the solution and the solution itself was created in MS Visual Studio 2015, MS SQL Management Studio and Power BI.

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Lundstedt, Mattias, and Axel Norell. "Prototyp för dynamiskt beslutsstöd." Thesis, Linköpings universitet, Interaktiva och kognitiva system, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-108954.

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Företaget Nethouse har haft uppdraget att kravställa, utveckla och implementera ett verksamhetssystem åt Sveriges Skorstensfejaremästares Riksförbund (SSR). Medlemsföretagen i SSR bedriver sotarverksamhet på uppdrag av Sveriges kommuner och är beroende av insamlad data kopplad till deras verksamhet. I det nyutvecklade systemet, som går under namnet Ritz, samlas informationen i en central databas och är tillgänglig för flertalet intressenter med hjälp av ny teknik och modernare lösningar. Systemet är helt webbaserat och körs som en molntjänst, tillgängligt via antingen en webbsida eller som mobilapplikation. Åtkomsten av data baseras på företagsnivå på ”stämplad” data i databasen och för att reglera åtkomsten för företagsanvändare till respektive företags data används rollbaserad åtkomstkontroll. Detta examensarbete har syftat till att utveckla en prototyp till en beslutsstödslösning för dynamisk åtkomst till de datamängder som lagras inom Ritz. Nethouse har efterfrågat en prototyp för en BI-lösning som visar på möjligheter och fördelar för intressenter till Ritz med att implementera en sådan. Då integration och förvaltning är viktiga faktorer för Nethouse har ett krav på prototypen varit att den utvecklats inom Microsofts programvaror, precis som resten av Ritz. Prototypen färdigställdes genom konstruerandet av ett centralt data warehouse enligt Ralph Kimballs metodologier och genom implementation av en OLAP-kub byggd i Microsoft SSAS. Dataöverföringen från datakällorna till beslutsstödslösningens data warehouse skedde genom utvecklandet av en ETL-process i Microsoft SSIS. Den resulterande kuben har främst utformats för att kunna besvara den sortens frågor som länsstyrelser ställer till sotarföretag i kontrollsyfte och stöder förfrågningar mot de två centrala affärsprocesserna sotning och brandskyddskontroll. Dessa förfrågningar kan filtreras på flertalet dimensioner som exempelvis tid, utförare, status och kontrollutfall. Prototypen begränsar även åtkomst till den information som användare har rätt att ta del av genom att koppla samman användare och objekt till geografiska indelningar som kallas distrikt. Denna dynamiska säkerhetslösning ger goda förutsättningar för att kunna hantera förändringar i användarnas behörighet i framtiden. Genom den utvalda lösningen behålls den dynamiska naturen i systemet, då åtkomst till beslutsstödstjänsten kan fås genom flertalet källor som stödjer uppkoppling mot Microsofts multidimensionella beslutsstödslösningar, bland annat Excel och SQL Server Reporting Services.

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Carlsson, Jacob, and Edison Gashi. "SSDs påverkan på MySQL: En prestandajämförelse." Thesis, Linnéuniversitetet, Institutionen för datavetenskap, fysik och matematik, DFM, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-21266.

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Solid State Drives (SSD) blir idag allt vanligare som lagringsmedium och håller på att bli ett alternativ till magnetiska hårddiskar. Denna studie+ har undersökt hur man på bästa sätt kan utnjytta SSDer i en MySQL-databas. Undersökningen genomfördes med hjälp av experiment där prestandamätningar gjordes för att få en klar bild på i vilken konfiguration av SSDs som ger bäst prestanda i MySQL. Mätverktygen som användes var sql-bench och mysqlslap. Resultaten visar att en databas på en enskild SSD presterar lika bra som en databas med SSD-cache under majoriteten av mätningarna och visar bättre resultat än resterande konfigurationerna som var en databas på hårddisk och transaktionsloggen på en SSD. Solid State Drives (SSD) are now becoming more common as storage and is about to become an alternative to magnetic disks. This report studied how to best utilize SSDs in a MySQL database. This study was carried out using experiments in which performance benchmarks were made to get an accurate view on which configuration of SSDs that gives the best performance in MySQL. The benchmarks where made with sql-bench and mysqlslap. The results indicate that a database using only SSD storage performs equal to a database of solid-state cache under the majority of the tests and shows better results than the remaining configurations that include a database on a single hard drive and a configuration with the transaction log on a SSD.

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Roberto, Miguel Augusto Inácio. "Smart & Simple Business Solutions (SSBS)." Master's thesis, NSBE - UNL, 2010. http://hdl.handle.net/10362/10319.

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Petrusic, Dejan. "En studie av SSL." Thesis, Blekinge Tekniska Högskola, Avdelningen för för interaktion och systemdesign, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3537.

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Dokumentet är ett resultat av studier gjorda under kursen Kandidatarbete I Datavetenskap. Arbetet utforskade, genom fallstudie, två egenskaper av distribuerade informationssystem och relation mellan dessa: säkerhet och prestanda. Målet med fallstudien har varit att belysa nackdelen med användning av Secure Socker Layer (SSL) dvs. dess effekt på hastigheten och fördelen med SSL, dvs. SSL:s roll i informationssäkerhetsarbetet. Arbetet visar hur prestanda i ett tillämpad distribuerat informationssystem kan påverkas av en SSL tillämpning. Systemets responstid testades för skillnader mellan en SSL säkrad uppkoppling och utan. Det testade systemet var ett bokningssystem som används för administration av resor, utvecklat i DotNet utvecklingsplattform. Arbetet har dessutom visat genom studien av informationssäkerhetsstandarden ledningssystem för informationssäkerhet (LIS) vilken plats som SSL protokollet har i informationssäkerhetsarbetet i organisationer. Metoden för jämförelse utvecklades och baserades på interaktionsmodellen. Hypotesen för arbetet var att mjukvara som tillämpar SSL gör att responstiden blir längre men gör också att informationssystemet uppfyller krav enligt standarden för ledningssystem av informationssäkerhet SS-ISO/IEC 17799 och SS 62 77 99-2. Hypotesen bekräftades då resultatet för mätningen visade en ökning på 37,5 % i medel för klienten med säkrad SSL uppkoppling och att resultatet av LIS studien visade att organisationer uppfyller viktiga krav ställda i standarden genom at ha en SSL säkrad kommunikation i sitt informationssystem. This study shows the impact of SSL application on performance in a distributed information system. Further, the case study shows also, through studies of information security standard SS-ISO/IEC 17799, the place that SSL has in applying information security in organisations. dejanpetrusic@hotmail.com, is00dpe@student.bth.se

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Homaidi, Omar Al. "Data Remanence : Secure Deletion of Data in SSDs." Thesis, Blekinge Tekniska Högskola, Sektionen för datavetenskap och kommunikation, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-5165.

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The ongoing fast pace research in hardware and software technology has resulted in memory devices efficient and faster than ever before. However, the issue of security of the contained data is rarely discussed. There is an evident capability of these devices to retain data even when it is erased. In this thesis, a study is conducted to qualitatively analyze the extent to which data deletion is important and why secure deletion should be applied. Afterwards, following the sequential exploratory procedure, this paper presents an analysis of methods used to recover the data after being deleted in addition to the techniques used to securely delete this data. Based on this study, some recommendations are made to ensure the safety of data.

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Vinje, Eivind. "Educational implementation of SSL/TLS." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for datateknikk og informasjonsvitenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-13834.

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Bradley, Jeremy T. "The SSL Reference Implementation Project." Thesis, University of Bristol, 2000. http://hdl.handle.net/1983/916f1961-2fc1-461e-b76b-2c5d9fb18a5e.

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Книги з теми "SSLS"

Goyvaerts, Didier L., ed. African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.

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Lefebvre, Claire, ed. Serial Verbs. John Benjamins Publishing Company, 1991. http://dx.doi.org/10.1075/ssls.8.

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Ssss Sssss Ssss...!! Unaluna, 2011.

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Paleckis, Justas. SSRS-- mūsų akimis. Lietuvos žurnalistų sąjunga, 1990.

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Ianna, Andréadis, ed. SSSS: Snake art & allegory. Tara Books, 2010.

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Rubio, Ayalah. Madrikh lemidah le-SSPS. ha-Universiṭah ha-petuḥah, 2009.

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Tan, Bronson, ed. Applying RCS and SSCS. O'Reilly & Associates, 1995.

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Wolf, Gita. SSSS: Snake art & allegory. Tara Books, 2010.

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Micheloni, Rino. Inside Solid State Drives (SSDs). Springer Netherlands, 2013.

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Micheloni, Rino, ed. Solid-State-Drives (SSDs) Modeling. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-51735-3.

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Частини книг з теми "SSLS"

Abdoullaye, D., and J. Kelly. "On the ‘compound’ tone in Migaama." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.04abd.

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Bokamba, Eyamba G. "Verbal Agreement as a noncyclic rule in Bantu." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.05bok.

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Furere, R., and Annie Rialland. "Tons et accents en Kinyarwanda." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.07fur.

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Goldsmith, John A. "On tone in Sukuma." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.08gol.

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Grégoire, Claire. "L'expression du passif en Maninka." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.09gre.

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Huang, C. T. James. "The autosegmental and metrical nature of tone terracing." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.10hua.

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Hyman, Larry M., and N. Valinande. "Globality in the Kinande tone system." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.11hym.

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Kadima-Tshimanga, B. "Le motchômageet ses implications socio-politiques dansla Voix du Congolais." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.12kad.

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Katamba, Francis X. "A nonlinear account of the syllable in Luganda." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.13kat.

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Kaye, J. "On the syllable structure of certain West African languages." In African Linguistics. John Benjamins Publishing Company, 1985. http://dx.doi.org/10.1075/ssls.6.14kay.

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Тези доповідей конференцій з теми "SSLS"

Moser, H. O., M. Bahou, B. D. F. Casse, et al. "Research Frontiers at SSLS." In SYNCHROTRON RADIATION INSTRUMENTATION: Ninth International Conference on Synchrotron Radiation Instrumentation. AIP, 2007. http://dx.doi.org/10.1063/1.2436037.

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Nimelman, M., J. Tripp, G. Bailak, and J. Bolger. "Spaceborne scanning lidar system (SSLS)." In Defense and Security, edited by Peter Tchoryk, Jr. and Brian Holz. SPIE, 2005. http://dx.doi.org/10.1117/12.604203.

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Nimelman, M., J. Tripp, A. Allen, D. M. Hiemstra, and S. A. McDonald. "Spaceborne scanning lidar system (SSLS) upgrade path." In Defense and Security Symposium, edited by Edward M. Carapezza. SPIE, 2006. http://dx.doi.org/10.1117/12.666187.

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Jian, L. K., B. D. F. Casse, S. P. Heussler, et al. "X-ray-based Micro/Nanomanufacturing at SSLS — Technology and Applications." In SYNCHROTRON RADIATION INSTRUMENTATION: Ninth International Conference on Synchrotron Radiation Instrumentation. AIP, 2007. http://dx.doi.org/10.1063/1.2436352.

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Huie, J. C., R. Gentilman, and T. S. Stefanik. "Domestically produced ceramic YAG laser gain material for high power SSLs." In Defense and Security Symposium, edited by Gary L. Wood and Mark A. Dubinskii. SPIE, 2007. http://dx.doi.org/10.1117/12.719397.

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Bertazzi, F., F. Bonani, S. Donati Guerrieri, and G. Ghione. "Physics-based SS and SSLS variability assessment of microwave devices through efficient sensitivity analysis." In 2012 Workshop on Integrated Nonlinear Microwave and Millimetre-Wave Circuits (INMMIC). IEEE, 2012. http://dx.doi.org/10.1109/inmmic.2012.6331920.

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Bahou, Mohammed, Li Wen, Xiande Ding, et al. "Infrared Spectro/Microscopy at SSLS — Edge Effect Source in a Compact Superconducting Storage Ring." In SYNCHROTRON RADIATION INSTRUMENTATION: Ninth International Conference on Synchrotron Radiation Instrumentation. AIP, 2007. http://dx.doi.org/10.1063/1.2436133.

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Mundre, P., R. Sood, and S. Mohammed. "ACETIC ACID (AA) AND NARROW BAND IMAGING (NBI) FOR BETTER DELINEATION OF MARGINS IN SESSILE SERRATED LESIONS (SSLS)." In ESGE Days. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1704160.

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Zhou, Y. B., and R. G. Fenton. "Kinematic Structure Analysis and Classification of Single-Loop Spatial Linkage Mechanisms." In ASME 1992 Design Technical Conferences. American Society of Mechanical Engineers, 1992. http://dx.doi.org/10.1115/detc1992-0236.

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Abstract This paper covers the following areas: all practical and typical kinematic input pairs used in a single-loop spatial linkage mechanism (SSLM) are classified using a new symbolic system; four basic groups of SSLMs are defined; and a new kinematic structure classification criterion is proposed, which provides a method to determine the maximum finite number of closures for the mechanism and the maximum order of the input-output displacement equation, free of extraneous roots, describing the kinematics of the SSLMs.

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Suzuki, Nobuhisa, Takekazu Arakawa, and Andrey Arabey. "Strain-Based Pipeline Design in Harsh Environments Using Large Diameter High Strain Line Pipes." In 2014 10th International Pipeline Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/ipc2014-33421.

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This paper outlines the draft recommendations to be issued by Gazprom that deals with the advanced strain-based pipeline design to ensure pipeline integrity in harsh environments using stress-strain curve controlled high-strain line pipe (SSLP). The draft recommendations have been provided to employ the new design concept to some future pipeline projects. The analytical solution was adopted in the draft as the solution is useful to improve strain capacity by controlling the longitudinal tensile properties without increasing wall thickness. The concept was validated through full-scale bending test using X70, 1220 mm SSLPs. FEA clarified that the strain capacity in compression or bending of X70, 1420 mm SSLP, 9.8 MPa, is high compared to that of the standard line pipe (STLP). The strain demand required for the SSLP pipeline in the harsh environments shall be small compared to that for the STPL pipeline. The SSLP pipeline shall be beneficial for ensuring the pipeline integrity in the harsh environments.

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Звіти організацій з теми "SSLS"

Rescoria, Eric, and Kevin Dick. Authoritative SSL Auditor. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada457576.

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Smith-Fewell, M. A. TWRS safety SSCs: Requirements and characteristics. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/362380.

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Frankel, S. E., P. Hoffman, A. D. Orebaugh, and R. Park. Guide to SSL VPNs. National Institute of Standards and Technology, 2008. http://dx.doi.org/10.6028/nist.sp.800-113.

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Author, Not Given. SSPS results of test and operation, 1981-1984. Office of Scientific and Technical Information (OSTI), 1985. http://dx.doi.org/10.2172/6196812.

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Heikman, Sten. SSL Luminaire with Novel Driver Architecture. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1238366.

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none,. Solid-State Lighting (SSL) Manufacturing Workshops Report. Office of Scientific and Technical Information (OSTI), 2009. http://dx.doi.org/10.2172/1218294.

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Turner, S., and T. Polk. Prohibiting Secure Sockets Layer (SSL) Version 2.0. RFC Editor, 2011. http://dx.doi.org/10.17487/rfc6176.

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Ledbetter, Marc R. Multi-Year SSL Market Development Support Plan. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1039849.

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Sean Evans. Efficient White SSL Component for General Illumination. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1027980.

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Freier, A., P. Karlton, and P. Kocher. The Secure Sockets Layer (SSL) Protocol Version 3.0. RFC Editor, 2011. http://dx.doi.org/10.17487/rfc6101.

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