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Статті в журналах з теми "SSLS"

Автор: Grafiati

Опубліковано: 23 червня 2021

Оновлено: 29 липня 2025

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1

Al-Shangiti, Ali M., Claire E. Naylor, Sean P. Nair, David C. Briggs, Brian Henderson, and Benjamin M. Chain. "Structural Relationships and Cellular Tropism of Staphylococcal Superantigen-Like Proteins." Infection and Immunity 72, no. 7 (2004): 4261–70. http://dx.doi.org/10.1128/iai.72.7.4261-4270.2004.

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ABSTRACT The staphylococcal superantigen-like proteins (SSLs) are a family of polymorphic paralogs encoded in the Staphylococcus aureus genome whose function is unknown. The crystal structure of SSL7 was determined and compared to that of SSL5 and that of a classical superantigen, streptococcal pyrogenic exotoxin. Although the overall architecture of the superantigen family is retained in both SSL7 and SSL5, there are significant differences in the structures which suggest that the characteristic major histocompatibility complex binding site of superantigens has been lost. To complement these

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2

Koymans, Kirsten J., Oliver Goldmann, Christofer A. Q. Karlsson, et al. "The TLR2 Antagonist Staphylococcal Superantigen-Like Protein 3 Acts as a Virulence Factor to Promote Bacterial Pathogenicity in vivo." Journal of Innate Immunity 9, no. 6 (2017): 561–73. http://dx.doi.org/10.1159/000479100.

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Toll-like receptor (TLR) signaling is important in the initiation of immune responses and subsequent instigation of adaptive immunity. TLR2 recognizes bacterial lipoproteins and plays a central role in the host defense against bacterial infections, including those caused by Staphylococcus aureus. Many studies have demonstrated the importance of TLR2 in murine S. aureus infection. S. aureus evades TLR2 activation by secreting two proteins, staphylococcal superantigen-like protein 3 (SSL3) and 4 (SSL4). In this study, we demonstrate that antibodies against SSL3 and SSL4 are found in healthy indi

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3

Yang, Dong-Hoon. "Understanding colorectal polyps to prevent colorectal cancer." Journal of the Korean Medical Association 66, no. 11 (2023): 626–31. http://dx.doi.org/10.5124/jkma.2023.66.11.626.

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Background: Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide. Most CRCs arise through carcinogenesis pathways from precancerous lesions, such as adenoma and sessile serrated lesions (SSLs). Understanding the characteristics of such precancerous colorectal polyps and the carcinogenesis pathways helps to develop CRC preventive strategies via screening, colonoscopic polypectomy, and surveillance.Current Concepts: Benign colorectal tumors can be classified as conventional adenomatous and serrated polyps. Conventional adenoma is one of the most prevalent pr

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4

Vu, Nhu Thi Hanh, Huy Minh Le, Diem Thi-Ngoc Vo, et al. "Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients." World Journal of Clinical Oncology 15, no. 2 (2024): 290–301. http://dx.doi.org/10.5306/wjco.v15.i2.290.

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BACKGROUND Sessile serrated lesions (SSLs) are considered precancerous colorectal lesions that should be detected and removed to prevent colorectal cancer. Previous studies in Vietnam mainly investigated the adenoma pathway, with limited data on the serrated pathway. AIM To evaluate the prevalence, risk factors, and BRAF mutations of SSLs in the Vietnamese population. METHODS This is a cross-sectional study conducted on patients with lower gastrointestinal symptoms who underwent colonoscopy at a tertiary hospital in Vietnam. SSLs were diagnosed on histopathology according to the 2019 World Hea

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5

Hermans, Stefan J., Heather M. Baker, Richard P. Sequeira, Ries J. Langley, Edward N. Baker, and John D. Fraser. "Structural and Functional Properties of Staphylococcal Superantigen-Like Protein 4." Infection and Immunity 80, no. 11 (2012): 4004–13. http://dx.doi.org/10.1128/iai.00764-12.

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ABSTRACTStaphylococcus aureusis a prevalent and significant human pathogen. Among the repertoire of virulence factors produced by this bacterium are the 14 staphylococcal superantigen-like (SSL) proteins. SSL protein 4 (SSL4) is one member of this family and contains a highly conserved carbohydrate binding site also found in SSL2, SSL3, SSL5, SSL6, and SSL11. Recombinant SSL4t, comprising amino acids 109 to 309 of Newman strain SSL4 (SSL4-Newman), has been shown to bind and be internalized by human granulocytes and macrophages in a sialic-acid (Sia)-dependent manner. SSL4tcan compete with itse

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6

Yokoyama, Ryosuke, Saotomo Itoh, Go Kamoshida, et al. "Staphylococcal Superantigen-Like Protein 3 Binds to the Toll-Like Receptor 2 Extracellular Domain and Inhibits Cytokine Production Induced by Staphylococcus aureus, Cell Wall Component, or Lipopeptides in Murine Macrophages." Infection and Immunity 80, no. 8 (2012): 2816–25. http://dx.doi.org/10.1128/iai.00399-12.

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ABSTRACTStaphylococcal superantigen-like proteins (SSLs) are a family of exoproteins sharing structural similarity with superantigens, but no superantigenic activity. Corresponding host target proteins or receptors against a portion of SSLs in the family have been identified. In this study, we show that SSL3 specifically binds to Toll-like receptor 2 (TLR2) and inhibits the stimulation of macrophages by TLR2 ligands. An approximately 100-kDa protein was recovered by using recombinant His-tagged SSL3-conjugated Sepharose from the lysate of porcine spleen, and the protein was identified as porci

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7

Francos, Nicolas, Daniela Heller-Pearlshtien, José A. M. Demattê, et al. "A Spectral Transfer Function to Harmonize Existing Soil Spectral Libraries Generated by Different Protocols." Applied and Environmental Soil Science 2023 (January 20, 2023): 1–17. http://dx.doi.org/10.1155/2023/4155390.

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Soil spectral libraries (SSLs) are important big-data archives (spectra associated with soil properties) that are analyzed via machine-learning algorithms to estimate soil attributes. Since different spectral measurement protocols are applied when constructing SSLs, it is necessary to examine harmonization techniques to merge the data. In recent years, several techniques for harmonization have been proposed, among which the internal soil standard (ISS) protocol is the most largely applied and has demonstrated its capacity to rectify systematic effects during spectral measurements. Here, we pos

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8

Florea, Maria-Alexandra, Gabriel Becheanu, and Andrei Niculae. "Immunohistochemical insights into the pathogenesis of colonic sessile serrated lesions." Archive of Clinical Cases 12, no. 1 (2025): 22–28. https://doi.org/10.22551/2025.46.1201.10307.

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Background: Sessile serrated lesions (SSLs) are recognized as precursor lesions in the pathogenesis of colorectal cancer, particularly in the context of microsatellite instability (MSI). This study evaluates the role of immunohistochemical (IHC) markers in understanding the molecular and immunologic characteristics of SSLs. Materials and Methods: A retrospective analysis was performed on 45 colonic neoplastic lesions diagnosed as SSLs. An IHC staining panel was conducted, including MLH1, p53, CD44, CD3, CD8, MUC2, MUC5AC, MUC6, chromogranin and Ki67 antibodies. Results: MLH1 and p53 expression

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9

Chayahara, Yuko, Yumiko Nakanowataru, Sara Abe, et al. "Human Impact on the Twenty-Four-Hour Patterns of Steller Sea Lions’ Use of a Haulout in Hokkaido, Japan." Animals 14, no. 9 (2024): 1312. http://dx.doi.org/10.3390/ani14091312.

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Steller sea lions (SSLs) migrate to the Hokkaido coast to spend the winter there, leading to conflicts arising with fishermen over herring. This study analyzed the trends in the SSLs’ use of a haulout as a rest site under human pressure. From January to March in 2017, 2018, and 2019, we recorded the SSL behavior at the haulout site off Otaru City, Hokkaido, for 24 h a day using a fixed-point video recorder. We investigated three years of data to analyze the relationships between the SSL behaviors (attendance/landing–entry timings/remaining on land) and herring caught. We also monitored the SSL

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10

Diogoul, Ndague, Patrice Brehmer, Yannick Perrot, et al. "Fine-scale vertical structure of sound-scattering layers over an east border upwelling system and its relationship to pelagic habitat characteristics." Ocean Science 16, no. 1 (2020): 65–81. http://dx.doi.org/10.5194/os-16-65-2020.

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Abstract. Understanding the relationship between sound-scattering layers (SSLs) and pelagic habitat characteristics is a substantial step to apprehend ecosystem dynamics. SSLs are detected on echo sounders representing aggregated marine pelagic organisms. In this study, SSL characteristics of zooplankton and micronekton were identified during an upwelling event in two contrasting areas of the Senegalese continental shelf. Here a cold upwelling-influenced inshore area was sharply separated by a strong thermal boundary from a deeper, warmer, stratified offshore area. Mean SSL thickness and SSL v

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11

Zhou, You Ya, Hui Yan Zhou, Yan Dong Tang, et al. "Development of Soil Screening Levels for Contaminated Sites Assessment in Beijing." Applied Mechanics and Materials 209-211 (October 2012): 1100–1105. http://dx.doi.org/10.4028/www.scientific.net/amm.209-211.1100.

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The Risk Based Corrective Action (RBCA) Tool Kit for Chemical Releases was used to develop Soil Screening Levels (SSLs) for contaminated sites assessment in Beijing. A total 88 contaminants, including inorganic compounds, volatile organic compounds, semi-volatile organic compounds, pesticides, polybrominated biphenyls and others, were identified as the priority compounds of concern, and a range of exposure parameters, toxicological data and site factors based on the environmental monitoring data from several contaminated sites in Beijing, were used as model inputs to derive SSLs. The proposed

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12

Mandomando, Inacio, Jason M. Mwenda, Tomoka Nakamura, et al. "Evaluation of Laboratories Supporting Invasive Bacterial Vaccine-Preventable Disease (IB-VPD) Surveillance in the World Health Organization African Region, through the Performance of Coordinated External Quality Assessment." Tropical Medicine and Infectious Disease 8, no. 8 (2023): 413. http://dx.doi.org/10.3390/tropicalmed8080413.

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(1) Background: Laboratories supporting the invasive bacteria preventable disease (IB-VPD) network are expected to demonstrate the capacity to identify the main etiological agents of pediatric bacterial meningitis (PBM) (Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae) on Gram stains and in phenotypic identification. Individual reports of sentinel site (SSL), national (NL) and regional reference (RRL) laboratories participating in the World Health Organization (WHO)-coordinated external quality assessment, distributed by the United Kingdom National External Quality

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13

Vishnu Prasanth, P., S. Sridharan, Y. Bhavani Kumar, and D. Narayana Rao. "Lidar observations of sporadic Na layers over Gadanki (13.5° N, 79.2° E)." Annales Geophysicae 25, no. 8 (2007): 1759–66. http://dx.doi.org/10.5194/angeo-25-1759-2007.

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Abstract. We studied the characteristics of sporadic sodium layers (SSLs) observed with the sodium (Na) resonance scattering lidar at Gadanki (13.5° N, 79.2° E). The SSLs were observed on a total of 63 occasions during 464 h of Na lidar observations from January 2005 to February 2006. The observations showed that one SSL event occurred, on average, every 7 h. The most prominent sporadic layer, which formed on 12 February 2005, exhibited a peak density of 60 722 Na atoms/cm³ around 92 km and it was nearly twice the peak density reported from elsewhere using ground-based observations. In general

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14

Macarie, Melania, Simona Bataga, Simona Mocan, et al. "Correlation of Metabolic Risk Factors with Sessile Serrated Lesions." Journal of Gastrointestinal and Liver Diseases 29, no. 2 (2020): 175–79. http://dx.doi.org/10.15403/jgld-507.

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Background and Aims: The importance of sessile serrated lesions (SSLs) in the pathogenesis of colorectal carcinoma has been recently established. These are supposed to cause the so-called “interval cancer”, having a rapidly progressive growth and being difficult to detect and to obtain an endoscopic complete resection. We aimed to establish the most important metabolic risk factors for sessile serrated lesions. Methods: We performed a retrospective case-control study, on a series of 2918 consecutive patients who underwent colonoscopy in Gastroenterology and Endoscopy Unit, County Clinica

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15

Nishizawa, Toshihiro, Osamu Toyoshima, Shuntaro Yoshida, et al. "TXI (Texture and Color Enhancement Imaging) for Serrated Colorectal Lesions." Journal of Clinical Medicine 11, no. 1 (2021): 119. http://dx.doi.org/10.3390/jcm11010119.

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Background and aim: Olympus Corporation released the texture and color enhancement imaging (TXI) technology as a novel image-enhancing endoscopic technique. We investigated the effectiveness of TXI in the imaging of serrated colorectal polyps, including sessile serrated lesions (SSLs). Methods: Serrated colorectal polyps were observed using white light imaging (WLI), TXI, narrow-band imaging (NBI), and chromoendoscopy with and without magnification. Serrated polyps were histologically confirmed. TXI was compared with WLI, NBI, and chromoendoscopy for the visibility of the lesions without magni

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16

Yang, S. L., R. Sandven, and L. Grande. "Steady-state lines of sand–silt mixtures." Canadian Geotechnical Journal 43, no. 11 (2006): 1213–19. http://dx.doi.org/10.1139/t06-069.

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The steady-state lines (SSLs) for sand–silt mixtures with various fines contents (0%, 5%, 10%, 15%, 20%, 30%, 50%, 70%, and 94%) were studied. It was indicated that the location of the SSL in the e–p′ space is different for each mixture, but the SSLs are parallel. In the e – ln p′ plot, the SSLs are similar for the mixtures with a fines content of less than the transitional fines content (TFC) when tested under drained and undrained conditions and the intergranular and interfine void ratios are used. The data diverge when the fines contents are equal to or greater than the TFC, even though the

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17

Kim, Jeongseok, Tae-Geun Gweon, Min Seob Kwak, et al. "A survey of current practices in post-polypectomy surveillance in Korea." Intestinal Research 22, no. 2 (2024): 186–207. http://dx.doi.org/10.5217/ir.2023.00109.

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Background/Aims: We investigated the clinical practice patterns of post-polypectomy colonoscopic surveillance among Korean endoscopists.Methods: In a web-based survey conducted between September and November 2021, participants were asked about their preferred surveillance intervals and the patient age at which surveillance was discontinued. Adherence to the recent guidelines of the U.S. Multi-Society Task Force on Colorectal Cancer (USMSTF) was also analyzed.Results: In total, 196 endoscopists completed the survey. The most preferred first surveillance intervals were: a 5-year interval after t

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18

Khalifa, Saoussane, Masaru Enomoto, Shunji Kato, and Kiyotaka Nakagawa. "Novel Photoinduced Squalene Cyclic Peroxide Identified, Detected, and Quantified in Human Skin Surface Lipids." Antioxidants 10, no. 11 (2021): 1760. http://dx.doi.org/10.3390/antiox10111760.

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Skin surface lipids (SSLs) form the first barrier that protects the human organism from external stressors, disruption of the homeostasis of SSLs can result in severe skin abnormalities. One of the main causes of this disruption is oxidative stress that is primarily due to SSLs oxidation. Squalene (SQ), the most abundant lipid among SSLs, was shown to first undergo singlet molecular oxygen (1O2) oxidation to yield 6 SQ-monohydroperoxide (SQ-OOH) isomers as the primary oxidation products. However, due to the instability and lability of hydroperoxides, we found that when total SQ-OOH isomers are

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19

Shafiq, Sameera, and Iram Naz. "An Assessment of Perinatal Distress and Marital Relationships in Couples: A Validation Study." Human Nature Journal of Social Sciences 5, no. 1 (2024): 1–11. https://doi.org/10.71016/hnjss/qhgw0s63.

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Aim of the Study: The study conducted to assess the validation of the Major Depressive Disorder Subscale (MDDS) and Generalized Anxiety Disorder Subscale (GADS) in Parental Perinatal Distress Scale (PPDS) and to assess the validation of Scale of Marital Intimacy (SMI) and the Satisfaction with Sex Life Scale-Revised (SSLS-R). Methodology: In study 1, Perinatal Depression Inventory (PDI) and Perinatal Anxiety Screening Scale (PASS) were translated from English into Urdu in phase I. In the phase II, Urdu versions of PDI and PASS were administered along with MDDS, GADS, and Urdu version of Subjec

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20

Li, Jie, Hiroaki Okamoto, Chunyue Yin, et al. "Proteomic characterization of primary diffuse large B-cell lymphomas in the central nervous system." Journal of Neurosurgery 109, no. 3 (2008): 536–46. http://dx.doi.org/10.3171/jns/2008/109/9/0536.

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Object The lack of primary lymphoid tissue within the central nervous system (CNS) confounds our understanding of the pathogenesis of primary CNS lymphomas (PCNSLs). Comparing the protein expression of PCNSLs and sporadic systemic lymphomas (SSLs) provides a useful strategy for identifying a molecular signature that characterizes disease-associated features and provides information regarding tumor initiation and progression. Methods Seven diffuse large B-cell PCNSLs were selected to undergo 2D gel electrophoresis, and profiled proteomes from these PCNSLs were compared with those from 7 diffuse

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21

Wang, Jiahui, Yu Zhang, Xinyi Chen, et al. "Single-Cell Transcriptomics Reveals Cellular Heterogeneity and Drivers in Serrated Pathway-Driven Colorectal Cancer Progression." International Journal of Molecular Sciences 25, no. 20 (2024): 10944. http://dx.doi.org/10.3390/ijms252010944.

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Serrated lesions are common precancerous pathways in colorectal cancer (CRC), but the process by which they progress to malignancy remains unclear. We aimed to elucidate this progression through a single-cell RNA landscape. We conducted single-cell RNA sequencing on three normal colonic tissues and fifteen SLs (including HPs, SSLs, SSLD, and TSAs) and integrated these data with datasets containing tumor samples. We identified three invasive malignant epithelial cell subtypes related to CRC progression: SLC1, SLC2, and tumor cell. SLC1, specific to SSLs, is involved in cell proliferation and sh

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22

Roa, Lina, Maryse Larouche, Momoe Hyakutake, et al. "COMET (Composite Outcomes of Mesh vs suture Techniques for prolapse repair)- Protocol for a single blind randomized controlled multicenter trial testing surgical innovation in female pelvic surgery." PLOS ONE 19, no. 10 (2024): e0308926. http://dx.doi.org/10.1371/journal.pone.0308926.

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Background Pelvic organ prolapse (POP) increases in incidence and severity with aging. At least 1 in 4 women seek pelvic floor care and many more suffer with concurrent symptoms of bowel, bladder and sexual dysfunction, which can have a large impact on quality of life. It is estimated that 1 in 5 women will undergo surgery for POP. POP is difficult to cure with existing surgeries and therefore treatment failure and reoperations are common. Surgical innovation in this area is urgently needed and we have developed a novel technique of bilateral sacrospinous vaginal vault fixation with synthetic

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23

Terzić, Elena, Clara Gardiol, and Ivica Vilibić. "Surface saline lakes in the Mediterranean Sea." Ocean Science 21, no. 4 (2025): 1441–59. https://doi.org/10.5194/os-21-1441-2025.

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Abstract. In the Levantine basin, it has long been known that salinity can reach a maximum in a thin layer near the surface, particularly during the warm season when summer heating, evaporation, and low mixing prevail. This water mass has been linked to the generation of Levantine intermediate and deep waters, depending on winter heat loss and wind-induced mixing. However, a recent study demonstrated that similar conditions, referred to as surface saline lakes (SSLs), can occur as far north as the Adriatic Sea. To investigate this, we analysed data from Argo profiling floats across all of the

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24

Shaukat, Aasma, Douglas K. Rex, Michael Shyne, Timothy R. Church, Joseph P. Moscatelli, and Joshua B. Colton. "Effect of a polyp detection poster on detection of sessile serrated lesions: a prospective controlled study." Endoscopy International Open 10, no. 04 (2022): E534—E538. http://dx.doi.org/10.1055/a-1784-0313.

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Abstract Background and study aims Colonoscopy is effective in reducing the incidence of colorectal cancer, but interval cancers remain a concern and their occurrence mainly is thought to be due to poor detection of sessile serrated lesions (SSLs) and advanced neoplasia (AN). Currently there are no low-cost, easy-to-implement tools to improve detection of difficult-to-detect polyps. Our aims were to compare the detection rate for SSLs and AN between two groups of endoscopists at a large community practice, one of which received an intervention of a polyp detection poster displayed over the mon

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25

Mouget, Anne, Patrice Brehmer, Yannick Perrot, et al. "Applying Acoustic Scattering Layer Descriptors to Depict Mid-Trophic Pelagic Organisation: The Case of Atlantic African Large Marine Ecosystems Continental Shelf." Fishes 7, no. 2 (2022): 86. http://dx.doi.org/10.3390/fishes7020086.

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To identify key nonspecific organisational characteristics of the mid-trophic pelagic communities, which remain a challenge, we work with sound scattering layers (SSLs). Application was tested in the three African Atlantic Large Marine Ecosystems (AALMEs) to assess the utility of adapting and developing new acoustic variables. Our methodology allowed comparison between Large Marine Ecosystems (LMEs) based on 14 morphological, spatial and acoustic variables to characterize SSLs over time. These original variables were effective in monitoring and comparing the LMEs, and even allowed us to discri

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Moser, H. O., B. D. F. Casse, E. P. Chew, et al. "Status of and materials research at SSLS." Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 238, no. 1-4 (2005): 83–86. http://dx.doi.org/10.1016/j.nimb.2005.06.022.

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Zhou, Lihong, Yaqian Song, and Tong Zhou. "Underutilisation of self-service libraries in Chinese cities." Library Hi Tech 34, no. 3 (2016): 521–38. http://dx.doi.org/10.1108/lht-05-2016-0054.

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Purpose Self-service libraries (SSLs) have been regarded as an effective approach to provide convenient book services to the enormously large populations of China’s cities. These SSLs are in fact automatic book service machines, which provide a combination of services, including reading card issuing, book lending and returning, and book reservations and collection. However, despite acclaimed success, SSL services are not well received by patrons and are underutilised. The purpose of this paper is to identify and understand the causes of the underutilisation of SSL services in Chinese cities. D

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28

Miao, Tianyu, Wenjun Ji, Baoguo Li, et al. "Advanced Soil Organic Matter Prediction with a Regional Soil NIR Spectral Library Using Long Short-Term Memory–Convolutional Neural Networks: A Case Study." Remote Sensing 16, no. 7 (2024): 1256. http://dx.doi.org/10.3390/rs16071256.

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Soil analysis using near-infrared spectroscopy has shown great potential to be an alternative to traditional laboratory analysis, and there is continuously increasing interest in building large-scale soil spectral libraries (SSLs). However, due to issues such as high non-linearity in soil spectral data and complexity in soil spatial variation, the establishment of robust prediction models for soil spectral libraries remains a challenge. This study aimed to investigate the performance of deep learning algorithms, including long short-term memory (LSTM) and LSTM–convolutional neural networks (LS

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29

Tambunan, Tulus. "Long-term Development of Small-scale Industries in Relation to Economic Development: Looking for General Propositions." Pakistan Development Review 33, no. 2 (1994): 165–90. http://dx.doi.org/10.30541/v33i2pp.165-190.

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The growing attention, in literature on economic development, towards the role of Small-scale Industries (SSls) within the economy of the less developed countries (LDCs), is strongly associated with the recognised current economic and social problems of continuing imbalance in the labour market leading to high unemployment rates, the persistence of large intra- and inter-regional socio-economic inequalities; and the consolidation of extremely concentrated patterns of urbanisation, facing these countries. On the other hand, there is the notion stating that the importance of SSls decreases with

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Chen, Tian, Mengzhen Zhao, and Zhenxing Mao. "Lipidomic Analysis of Hand Skin Surface Lipids Reveals Smoking-Related Skin Changes." Metabolites 13, no. 2 (2023): 254. http://dx.doi.org/10.3390/metabo13020254.

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Smoking contributes to the formation of skin wrinkles and reduces skin function, but the mechanism is not yet fully proven. This study aims to compare and analyze the effects of smoking on skin lipids and to further investigate the harmful effects of smoking on the skin. A total of 40 subjects (20 male smokers and 20 healthy control males) were recruited for this study. Measurement of hand skin-surface lipids (SSLs) in smoking and healthy control groups was undertaken using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS). Multivariate data an

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Dutta, Debabrata, Anirudha Dutta, Atanu Bhattacharjee, Amit Basak, and Amit Kumar Das. "Cloning, expression, crystallization and preliminary X-ray diffraction studies of staphylococcal superantigen-like protein 1 (SSL1)." Acta Crystallographica Section F Structural Biology Communications 70, no. 5 (2014): 600–603. http://dx.doi.org/10.1107/s2053230x14006967.

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Staphylococcus aureusproduces a family of exotoxins which are structural homologues of superantigens and thus are called staphylococcal superantigen-like proteins (SSLs). Amongst the 14 SSL genes,ssl1(SAOUHSC_00383) has been cloned in the pQE30 expression vector, overexpressed inEscherichia coliM15 (pREP4) cells and the protein purified to homogeneity. The protein was crystallized using 6% Tacsimate pH 6.0, 0.1 MMES pH 6.0, 25%(w/v) polyethylene glycol 3350, 100 mMNDSB 256 at 298 K by the sitting-drop vapour-diffusion method. The crystals belonged to space groupP21, with unit-cell parametersa=

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Itoh, Saotomo, Eri Hamada, Go Kamoshida, Kana Takeshita, Teruaki Oku, and Tsutomu Tsuji. "Staphylococcal Superantigen-Like Protein 5 Inhibits Matrix Metalloproteinase 9 from Human Neutrophils." Infection and Immunity 78, no. 7 (2010): 3298–305. http://dx.doi.org/10.1128/iai.00178-10.

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ABSTRACT Staphylococcal superantigen-like proteins (SSLs) constitute a family of exoproteins exhibiting structural similarities to superantigens and enterotoxins but no superantigenic activity. In this article, we present evidence that SSL5 specifically binds to matrix metalloproteinase 9 (MMP-9) and inhibits its enzymatic activity. When human neutrophil cell lysate was applied to recombinant His-tagged SSL5 conjugated to Sepharose, the bound fraction gave a major band of approximately 100 kDa in SDS-polyacrylamide gel electrophoresis. This protein was identified as the proform of MMP-9 (proMM

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Tan, Yi Yuan, Gary Sei Kiat Tay, Yu Jun Wong, et al. "Clinical Features and Predictors of Dysplasia in Proximal Sessile Serrated Lesions." Clinical Endoscopy 54, no. 4 (2021): 578–88. http://dx.doi.org/10.5946/ce.2020.198.

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Background/Aims: Proximal colorectal cancers (CRCs) account for up to half of CRCs. Sessile serrated lesions (SSLs) are precursors to CRC. Proximal location and presence of dysplasia in SSLs predict higher risks of progression to cancer. The prevalence of dysplasia in proximal SSLs (pSSLs) and clinical characteristics of dysplastic pSSLs are not well studied.Methods: Endoscopically resected colonic polyps at our center between January 2016 and December 2017 were screened for pSSLs. Data of patients with at least one pSSL were retrieved and clinicopathological features of pSSLs were analysed. p

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Uworwabayeho, Alphonse, Evariste Minani, Leon Mugabo, and Théophile Nsengimana. "Assessing Satisfaction of Science School Subject Teachers and Leaders in Rwanda on the Continuous Professional Development through Online Learning." International Journal of Learning, Teaching and Educational Research 21, no. 7 (2022): 379–96. http://dx.doi.org/10.26803/ijlter.21.7.20.

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In Rwanda, social, economic, and educational activities have recently been affected by the COVID-19 pandemic. After its outbreak, schools closed, and one of the alternatives opted for was online learning. This study assessed the satisfaction of school subject leaders (SSLs) and school leaders (SLs) with online learning and identified opportunities and challenges for the improvement of online learning. The study was guided by a professional development framework and design for online teaching. Data were gathered through an online survey and a Zoom meeting with 158 SSLs and 120 SLs purposively c

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Uworwabayeho, Alphonse, Evariste Minani, Leon Mugabo, and Théophile Nsengimana. "Assessing Satisfaction of Science School Subject Teachers and Leaders in Rwanda on the Continuous Professional Development through Online Learning." International Journal of Learning, Teaching and Educational Research 21, no. 7 (2022): 379–96. http://dx.doi.org/10.26803/ijlter.21.7.20.

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In Rwanda, social, economic, and educational activities have recently been affected by the COVID-19 pandemic. After its outbreak, schools closed, and one of the alternatives opted for was online learning. This study assessed the satisfaction of school subject leaders (SSLs) and school leaders (SLs) with online learning and identified opportunities and challenges for the improvement of online learning. The study was guided by a professional development framework and design for online teaching. Data were gathered through an online survey and a Zoom meeting with 158 SSLs and 120 SLs purposively c

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Kibble, Natalie A. J., M. Mehdi Sohani, Neil Shirley, et al. "Phylogenetic analysis and functional characterisation of strictosidine synthase-like genes in Arabidopsis thaliana." Functional Plant Biology 36, no. 12 (2009): 1098. http://dx.doi.org/10.1071/fp09104.

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Monoterpenoid indole alkaloids (MIA) are a diverse class of secondary metabolites important for plant protection and are drugs for treating human diseases. Arabidopsis thaliana (L.) is not known to produce MIAs, yet its genome has 15 genes with similarity to the periwinkle (Catharanthus roseus (L.) G. Don) strictosidine synthase (STR) gene. Phylogenetic analysis of strictosidine synthase-like (SSL) proteins reveals four well supported classes of SSLs in Arabidopsis. To determine if Arabidopsis produces active strictosidine synthase, Arabidopsis protein extracts were assayed for enzymatic activ

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Junchao, Ge, Go Tze Fong, Teo Hiu Hong, and Wang Lipeng. "Study on Function and Appearance Design of Smart Street Lamps Based on Kansei Engineering: A Literature Review." Jurnal Kejuruteraan 35, no. 5 (2023): 1227–38. http://dx.doi.org/10.17576/jkukm-2023-35(5)-22.

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The potential of smart cities to alleviate the challenges of urban development in relation to population, resources, and environment is widely recognized, making it a key urban development trend for the future. Smart street lamps (SSLs) are a crucial component of smart city infrastructure. However, their current unreasonable function settings and appearance design do not meet the emotional needs of residents and come at a high construction cost, resulting in decreased user satisfaction. Based on WOS and CNKI databases, 39 literatures on the aspects of theory, steps and technologies of KE, 32 l

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Mezzapesa, Martino, Giuseppe Losurdo, Francesca Celiberto, et al. "Serrated Colorectal Lesions: An Up-to-Date Review from Histological Pattern to Molecular Pathogenesis." International Journal of Molecular Sciences 23, no. 8 (2022): 4461. http://dx.doi.org/10.3390/ijms23084461.

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Until 2010, colorectal serrated lesions were generally considered as harmless lesions and reported as hyperplastic polyps (HPs) by pathologists and gastroenterologists. However, recent evidence showed that they may bear the potential to develop into colorectal carcinoma (CRC). Therefore, the World Health Organization (WHO) classification has identified four categories of serrated lesions: hyperplastic polyps (HPs), sessile serrated lesions (SSLs), traditional serrated adenoma (TSAs) and unclassified serrated adenomas. SSLs with dysplasia and TSAs are the most common precursors of CRC. CRCs ari

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MOSER, H. O., and C. Z. DIAO. "TOWARDS LIGHT SOURCES FEATURING SUPERCONDUCTING MINIUNDULATORS." International Journal of Modern Physics B 21, no. 03n04 (2007): 508–12. http://dx.doi.org/10.1142/s0217979207042306.

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Besides the exploitation of the Helios 2 superconducting compact storage ring for user operations and for its own R&D work, SSLS envisions a 4th generation synchrotron light source to complement and, eventually, replace the current facility. This vision includes an accelerator system based on a superconducting linear accelerator with up to 5 recirculation loops for energy multiplication and recovery with the distinguishing feature that the light would be generated by superconducting mini- and micro-undulators. Under this programme, SSLS is pursuing the development of superconducting miniun

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Sharma, Kaushal, Harinder P. Singh, Ranjan Gupta, et al. "Stellar spectral interpolation using machine learning." Monthly Notices of the Royal Astronomical Society 496, no. 4 (2020): 5002–16. http://dx.doi.org/10.1093/mnras/staa1809.

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ABSTRACT Theoretical stellar spectra rely on model stellar atmospheres computed based on our understanding of the physical laws at play in the stellar interiors. These models, coupled with atomic and molecular line databases, are used to generate theoretical stellar spectral libraries (SSLs) comprising of stellar spectra over a regular grid of atmospheric parameters (temperature, surface gravity, abundances) at any desired resolution. Another class of SSLs is referred to as empirical spectral libraries; these contain observed spectra at limited resolution. SSLs play an essential role in derivi

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IONESCU, Olivia, Nicolae BACALBASA, Nahedd SABA, and Gabriel BANCEANU. "SACROSPINOUS LIGAMENT FIXATION FOR APICAL PROLAPSE REPAIR COMPARED TO OTHER VAGINAL PROCEDURES." Romanian Journal of Medical Practice 12, no. 4 (2017): 208–11. http://dx.doi.org/10.37897/rjmp.2017.4.6.

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The vaginal procedures for uterine prolapse and/or vaginal vault prolapse are based on the attachment of the vaginal apex at the sacrospinous ligament (SL), the uterosacral ligaments (USL) or the iliococcygeus fascia. The fixation at the sacrospinous ligament (SSL) known as sacrospinous ligament fixation (SSLF) is the most studied and performed method for apical prolapse repair. Generally, it is preferred for cases of vaginal vault prolapse post-hysterectomy compared with the suspension at the uterosacral ligament (USLS) that it is usually performed at the time of uterus removal. Due to its as

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Vemulapalli, Krishna C., Rachel E. Lahr, and Douglas K. Rex. "Most large colorectal polyps missed by gastroenterology fellows at colonoscopy are sessile serrated lesions." Endoscopy International Open 10, no. 05 (2022): E659—E663. http://dx.doi.org/10.1055/a-1784-0959.

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Abstract Background and study aims Data on adenoma and sessile serrated lesion (SSL) miss rates for gastroenterology fellows during colonoscopy are limited. We aimed to describe the miss rate of fellows based on a second examination by a colonoscopist with a high rate of detection. Patients and methods Second- and third-year gastroenterology fellows at a single, tertiary center performed initial examinations. A single experienced attending doctor then performed a complete examination of the colon. We recorded the size and pathology of all lesions found at both examinations and calculated the a

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Crockett, Seth D., Elizabeth L. Barry, Leila A. Mott, Dale C. Snover, Kristin Wallace, and John A. Baron. "Predictors of Incident Serrated Polyps: Results from a Large Multicenter Clinical Trial." Cancer Epidemiology, Biomarkers & Prevention 31, no. 5 (2022): 1058–67. http://dx.doi.org/10.1158/1055-9965.epi-21-1226.

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Abstract Background: Serrated polyps (SP) are important colorectal cancer precursors, yet their epidemiology is incompletely understood. We measured risk factors for incident sessile-serrated lesions (SSL) and microvesicular (MVHP) and goblet-cell rich (GCHP) hyperplastic polyp subtypes. Methods: We conducted a cohort study of patients undergoing colonoscopic surveillance nested within a chemoprevention trial. Outcomes of interest were ≥1 SPs, including SSLs, MVHPs, and GCHPs specifically. Multivariable generalized estimating equation models were used to estimate adjusted risk ratios (RR) and

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McGillion, Michael, Adam Dubrowski, Robyn Stremler, et al. "The Postoperative Pain Assessment Skills Pilot Trial." Pain Research and Management 16, no. 6 (2011): 433–39. http://dx.doi.org/10.1155/2011/278397.

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BACKGROUND/OBJECTIVES: Pain-related misbeliefs among health care professionals (HCPs) are common and contribute to ineffective postoperative pain assessment. While standardized patients (SPs) have been effectively used to improve HCPs’ assessment skills, not all centres have SP programs. The present equivalence randomized controlled pilot trial examined the efficacy of an alternative simulation method – deteriorating patient-based simulation (DPS) – versus SPs for improving HCPs’ pain knowledge and assessment skills.METHODS: Seventy-two HCPs were randomly assigned to a 3 h SP or DPS simulation

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Andrea, Mille, Rikke Karlin Jepsen, Mads Falk Klein, Ismail Gögenur, and Tine Plato Kuhlmann. "Colorectal serrated lesions and polyps in the Danish population: A large nationwide register-based cohort study." Endoscopy International Open 11, no. 12 (2023): E1116—E1122. http://dx.doi.org/10.1055/a-2206-4486.

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Abstract Background and study aims Colorectal serrated lesions and polyps (SPs) include hyperplastic polyps (HP), sessile serrated lesions-/+dysplasia (SSL/SSL-D), and traditional serrated adenomas (TSA). From 20% to 30% of colorectal cancers (CRC) develop from SP. We present incidence and baseline characteristics of SP in a Danish cohort. Patients and methods We used The Danish Pathology Registry to include all SPs in the Danish population from January 1, 2000 to December 31, 2021. Based on the unique Danish personal identification number and SNOMED-codes, combined with the age and sex of pat

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Rahman, M. M., K. Kurumatani, H. Matada, T. Tambo, and C. Tatsuyama. "MBE grown short-period (Sim/Gen)N superlattices (SSLs) and its effect on the growth of uniform Si0.75Ge0.25/(SSLs)/Si(001) systems." Materials Science and Engineering: B 89, no. 1-3 (2002): 252–56. http://dx.doi.org/10.1016/s0921-5107(01)00796-6.

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Witten, Brandon L., Samuel H. Cheong, Diane Rodden, Rodrigo A. Alvarez, Avin Aggarwal, and Joshua Melson. "569 METACHRONOUS ADVANCED NEOPLASIA RATES IN PATIENTS WITH ISOLATED SESSILE SERRATED LESIONS (SSLS) VERSUS THOSE WITH SSLS WITH CONCOMITANT SMALL TUBULAR ADENOMAS." Gastroenterology 166, no. 5 (2024): S—136. http://dx.doi.org/10.1016/s0016-5085(24)00801-1.

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Dvořáková, Michaela. "Využití samoobslužných pokladen v maloobchodě: jejich vliv na zákaznickou spokojenost a vývoj těchto technologií na českém trhu." Trendy v podnikání 11, no. 1 (2021): 3–10. http://dx.doi.org/10.24132/jbt.2021.11.1.3_10.

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During the last few years consumer behavior has significantly changed. Implementation of self- service technologies (SSLs) has influenced interactions between consumer and retailer. Thanks to current situation, where social contacts are being restricted, the use of SSLs is growing. Due to this trend, there is a greater need to evaluate the impact of those technology on consumer behavior. Objective of this article is to review available research on consumer satisfaction at Self-service checkout and to asses situation at the Czech retail market. Result of literature review is not explicit and sh

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Low, Matthew Jian Wen, Gene Wai Han Chan, Zisheng Li, et al. "Comparison of virtual and in-person simulations for sepsis and trauma resuscitation training in Singapore: a randomized controlled trial." Journal of Educational Evaluation for Health Professions 21 (November 18, 2024): 33. http://dx.doi.org/10.3352/jeehp.2024.21.33.

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Purpose: This study aimed to compare cognitive, non-cognitive, and overall learning outcomes for sepsis and trauma resuscitation skills in novices with virtual patient simulation (VPS) versus in-person simulation (IPS).Methods: A randomized controlled trial was conducted on junior doctors in emergency departments from January to December 2022, comparing 70 minutes of VPS (n=19) versus IPS (n=21) in sepsis and trauma resuscitation. Using the nominal group technique, we created skills assessment checklists and determined Bloom’s taxonomy domains for each checklist item. Two blinded raters observ

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Li, Hongyang, Shengyao Jia, and Zichun Le. "Prediction of Soil Organic Carbon in a New Target Area by Near-Infrared Spectroscopy: Comparison of the Effects of Spiking in Different Scale Soil Spectral Libraries." Sensors 20, no. 16 (2020): 4357. http://dx.doi.org/10.3390/s20164357.

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Near-infrared (NIR) spectroscopy is widely used to predict soil organic carbon (SOC) because it is rapid and accurate under proper calibration. However, the prediction accuracy of the calibration model may be greatly reduced if the soil characteristics of some new target areas are different from the existing soil spectral library (SSL), which greatly limits the application potential of the technology. We attempted to solve the problem by building a large-scale SSL or using the spiking method. A total of 983 soil samples were collected from Zhejiang Province, and three SSLs were built according

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