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Статті в журналах з теми "Suxbat"

Автор: Grafiati

Опубліковано: 7 червня 2025

Оновлено: 2 серпня 2025

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1

Raxmonaliyeva, Robiyaxon. "BOLALARNI MAKTABDA TA' LIM OLISHIGA TAYYORGARLIGINI TASHXISLASH USULLARI." MULTIDISCIPLINARY JOURNAL: FUNDAMENTAL RESEARCH SCIENTIFIC JOURNAL 1, no. 4 (2025): 128–31. https://doi.org/10.5281/zenodo.15344943.

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Ushbu maqola bolalarning ta’lim olishga tayyorgorligini tashxislashga qaratilgn bo‘lib bu tekshiruv juda muxim hisoblanadi. Bolani o‘qitish uchun har tomonlama bilish kerak. Maqolada L.S.Vigotiskiy,S.L.Rubinshteyn, P.P.Blonskiy kabi olimlarning pisixolagik va pedagogik qarashlari asosida fikr yuritiladi.Shuningdek maktabgacha yoshdagi bolalarda qanday tashxislar o‘tkazilishi ,ko‘p ta’lim muossasalarining ota-onalar  bolalarni maktabga tayyorlash borasida faoliyatni olib borilishi yoritilgan.Tadqiqot natijalari bolalarni aqliy rivojlanishini tubdan o&lsq

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2

Ren, Li, Jie Wang, Ling Feng, Shuli Wang, and Jun Li. "Efficacy of Suxiao Jiuxin Pill on Coronary Heart Disease: A Meta-Analysis of Randomized Controlled Trials." Evidence-Based Complementary and Alternative Medicine 2018 (2018): 1–12. http://dx.doi.org/10.1155/2018/9745804.

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Suxiao jiuxin pill is considered an effective ancillary drug in patients with coronary heart disease. Although numerous small, single-center clinical trials have been conducted, the benefits and harms of suxiao jiuxin pill remain controversial. We performed a meta-analysis to clarify the efficacy of suxiao jiuxin pill on patients with coronary heart disease. Randomized controlled trials were identified by using the Cochrane Library, PubMed, Web of Science, Embase, Wanfang, Weipu, and China Knowledge Resource Integrated databases (until June 2016). Pooled relative risks (RR), weighted mean diff

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3

Xue, Yuwei, Kexuan Li, Wenli Feng, Zhongxiong Lai, and Shengcai Liu. "Identification of R2R3-MYB Transcription Factor Family Based on Amaranthus tricolor Genome and AtrMYB72 Promoting Betalain Biosynthesis by Directly Activating AtrCYP76AD1 Expression." Plants 14, no. 3 (2025): 324. https://doi.org/10.3390/plants14030324.

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MYB (myeloblastosis) is one of the most abundant transcription factors in plants which regulates various biological processes. The molecular characteristics and function of R2R3-MYB transcription factors in amaranth remain unclear. In this study, 73 R2R3-MYB members were identified from the amaranth genome database and we further analyzed their chromosome position, conserved motifs, physiological and biochemical features, collinearity relationships, gene structure, phylogeny and cis-acting element. Based on the phylogenetic and expression pattern analysis, 14 candidate R2R3-MYB genes might be

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4

Xie, Huiying, Jiajing Zeng, Wenli Feng, Wei Gao, Zhongxiong Lai, and Shengcai Liu. "Differential Expression of Amaranth AtrDODA Gene Family Members in Betalain Synthesis and Functional Analysis of AtrDODA1-1 Promoter." Plants 14, no. 3 (2025): 454. https://doi.org/10.3390/plants14030454.

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Betalains differ from anthocyanins, and they cannot coexist in the same plant under natural conditions. The L-DOPA 4,5-dioxygenase encoded by the DODA gene is a key step in the pathway of betalain biosynthesis in Caryophyllales plants. Amaranth is an important resource for the study and extraction of betalains. In order to clarify the function of AtrDODA family genes in betalain biosynthesis, we screened out three AtrDODA family gene members associated with betalains based on a genome database and RNA-seq databases of Amaranthus tricolor. Their characterization and expression pattern were furt

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5

Yu, Hao, Herong Gui, Honghai Zhao, et al. "Hydrochemical characteristics and water quality evaluation of shallow groundwater in Suxian mining area, Huaibei coalfield, China." International Journal of Coal Science & Technology 7, no. 4 (2020): 825–35. http://dx.doi.org/10.1007/s40789-020-00365-6.

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AbstractThe aim of this study is to evaluate the hydrogeochemical characteristics and water environmental quality of shallow groundwater in the Suxian mining area of Huaibei coalfield, China. The natural formation process of shallow groundwater in Suxian is explored using Piper trilinear charts and Gibbs diagrams, and by examining the ratios between the major ions. United States Salinity Laboratory (USSL) charts, Wilcox diagrams, and the water quality index (WQI) are further employed to quantify the differences in water quality. The results reveal that the main hydrochemical facies of groundwa

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6

P. I Aziba, P. I. Aziba, Tari R. Idumange, Senjobi, C. T, Adeniyi Akee M, and Adedokun Oluwasegun. "Studies on the Actions of Calcium Channel Blockers, Anticholinesterases Agents on Experimentally Induced Spastic Paralysis in Normotensive Rats." Biosciences Biotechnology Research Asia 19, no. 2 (2022): 365–71. http://dx.doi.org/10.13005/bbra/2991.

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Experimental paralysis was induced intramuscularly (i.m) in rats , using Suxa(1.08mg/kg ) , Deca (1.08mg/kg ) in normotensive rats weighing150-180g±2.5g (n=8).Various concentrations of these drugs ranging from (0.36—1.08mg/kg) were used , in order to assess at what concentrations will induced spastic paralysis sustained without death. Similarly, dose response concentrations effect was examined and the onset of action( ie time taken to observe paralysis and manifestation of pain and death was recorded. In some experiments, equimolar concentrations of Suxa(1.08mg/kg) and Deca(1.08mg/kg) was used

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7

Zhao, Zhigen, and Sheng Xue. "Multiple-Level Tectonic Control of Coalbed Methane Occurrence in the Huaibei Coalfield of Anhui Province, China." Energies 15, no. 14 (2022): 4977. http://dx.doi.org/10.3390/en15144977.

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The Huaibei coalfield is an important coal base and one of the hot spots of coalbed methane development in China. Therefore, a detailed understanding of gas occurrence in the Huaibei coalfield is of great significance. This paper analyzes the gas occurrence from the perspective of multiple-level tectonic control, i.e., the regional tectonic level, the coalfield tectonic level, the mining area tectonic level, and the coal mine tectonic level. This study deduces that gas occurrence in the Huaibei coalfield is characterized by multiple-level tectonic control. At the regional level, the Huaibei co

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8

Song, Daping, Dafang Zhuang, Dong Jiang, Jingying Fu, and Qiao Wang. "Integrated Health Risk Assessment of Heavy Metals in Suxian County, South China." International Journal of Environmental Research and Public Health 12, no. 7 (2015): 7100–7117. http://dx.doi.org/10.3390/ijerph120707100.

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9

Wu, Gaosong, Jing Zhong, Linlin Chen, et al. "Effects of the Suxiao Jiuxin pill on acute myocardial infarction assessed by comprehensive metabolomics." Phytomedicine 77 (October 2020): 153291. http://dx.doi.org/10.1016/j.phymed.2020.153291.

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10

Ruan, Xiao-fen, Cheng-wei Ju, Yan Shen, et al. "Suxiao Jiuxin pill promotes exosome secretion from mouse cardiac mesenchymal stem cells in vitro." Acta Pharmacologica Sinica 39, no. 4 (2018): 569–78. http://dx.doi.org/10.1038/aps.2018.19.

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11

Chen, Song, and Herong Gui. "Calculating groundwater mixing ratios in multi-aquifers based on statistical methods: a case study." Water Practice and Technology 16, no. 2 (2021): 621–32. http://dx.doi.org/10.2166/wpt.2021.027.

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Abstract Samples of river water and groundwater from Quaternary (QA), sandstone (SA), Taiyuan formation (TA), and Ordovician limestone (OA) aquifers in the Suxian coal-mining district, Anhui Province, China were collected. Their physicochemical properties, and major ion and isotopic compositions were determined. The samples were alkaline, with pH values exceeding 8, and the total dissolved solids concentrations depended on the water source. The δD and δ18O contents were highest in the river water samples and lowest in the SA groundwater. The isotopic characteristics of the QA and OA groundwate

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12

Ruan, Xiaofen, Tiejun Chen, Xiaolong Wang, and Yiping Li. "Suxiao Jiuxin Pill protects cardiomyocytes against mitochondrial injury and alters gene expression during ischemic injury." Experimental and Therapeutic Medicine 14, no. 4 (2017): 3523–32. http://dx.doi.org/10.3892/etm.2017.4964.

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13

Bai, Xiao-Yan, Ping Zhang, Qin Yang, et al. "Suxiao JiuxinPill Induces Potent Relaxation and Inhibition on Contraction in Human Artery and the Mechanism." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/956924.

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Suxiao JiuxinPill, a compound Chinese traditional medicine with main components of tetramethylpyrazine and borneol, is widely used for antiangina treatment in China but its pharmacological effect on human blood vessels is unknown. We investigated the effect and possible mechanism of SJP in the human internal mammary artery (IMA,n=78) taken from patients undergoing coronary surgery. SJP caused full relaxation in KCl- (99.4±10.5%,n=6) and U46619- (99.9±5.6%,n=6) contracted IMA. Pretreatment of IMA with plasma concentrations of SJP (1 mg/mL), calculated from the plasma concentration of its major

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14

LI, Chun-shen, Zhu-qiu QU, Sha-sha WANG, et al. "Effects of Suxiao Jiuxin Pill () on Oxidative Stress and Inflammatory Response in Rats with Experimental Atherosclerosis." Journal of Traditional Chinese Medicine 31, no. 2 (2011): 107–11. http://dx.doi.org/10.1016/s0254-6272(11)60022-8.

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15

Wu, Qiang, Han Liu, and Xu Wen Li. "Non-Uniformity Correction Algorithm Research Based on One FPGA Processor." Applied Mechanics and Materials 568-570 (June 2014): 265–69. http://dx.doi.org/10.4028/www.scientific.net/amm.568-570.265.

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The two-point non-uniformity correction based on Least mean square (LMS) algorithm which was proposed by Suxia Xing need one FPGA processor, one DSP processor and four SRAM chips. This will increase the cost and volume of the whole infrared system. In the LMS algorithm, this paper improves the estimation of the ideal signal, so that it can reduce the influence of blind elements and improve the effect of non-uniformity correction. Besides, this paper realizes the two-point non-uniformity correction based on LMS algorithm with only one FPGA processor and two SRAM chips in the final, this will re

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16

Qiang, Tingting, Yiping Li, Keyan Wang, et al. "Evaluation of potential herb-drug interactions based on the effect of Suxiao Jiuxin Pill on CYP450 enzymes and transporters." Journal of Ethnopharmacology 280 (November 2021): 114408. http://dx.doi.org/10.1016/j.jep.2021.114408.

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17

Song, Daping, Dong Jiang, Yong Wang, Wei Chen, Yaohuan Huang, and Dafang Zhuang. "Study on Association between Spatial Distribution of Metal Mines and Disease Mortality: A Case Study in Suxian District, South China." International Journal of Environmental Research and Public Health 10, no. 10 (2013): 5163–77. http://dx.doi.org/10.3390/ijerph10105163.

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18

Ruan, Xiao-fen, Yong-jun Li, Cheng-wei Ju, et al. "Exosomes from Suxiao Jiuxin pill-treated cardiac mesenchymal stem cells decrease H3K27 demethylase UTX expression in mouse cardiomyocytes in vitro." Acta Pharmacologica Sinica 39, no. 4 (2018): 579–86. http://dx.doi.org/10.1038/aps.2018.18.

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19

Li, Yiping, Xiaofen Ruan, Tiejun Chen, Junjie Gao та Xiaolong Wang. "Anti-apoptotic effect of Suxiao Jiuxin Pills against hypoxia-induced injury through PI3K/Akt/GSK3β pathway in HL-1 cardiomyocytes". Journal of the Chinese Medical Association 81, № 9 (2018): 816–24. http://dx.doi.org/10.1016/j.jcma.2018.02.002.

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20

Tan, Ya-fang, Juan Yu, Wen-jun Pan, Jian-yong Qi та Min-zhou Zhang. "Protective Mechanisms of Suxiao Jiuxin Pills (速效救心丸) on Myocardial Ischemia-Reperfusion Injury in vivo and in vitro". Chinese Journal of Integrative Medicine 26, № 8 (2020): 583–90. http://dx.doi.org/10.1007/s11655-020-2726-2.

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21

Song, Yu, Bo Jiang, Ming Li, Jie-Gang Liu, Guo-Xi Cheng, and Zheng Tang. "Nano-Porous Structural Evolution and Tectonic Control of Low-Medium Metamorphic Tectonically Deformed Coals—Taking Suxian Mine Field as an Example." Journal of Nanoscience and Nanotechnology 17, no. 9 (2017): 6083–95. http://dx.doi.org/10.1166/jnn.2017.14476.

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22

Yu, Peiyi, Chen Ning, Jingzhen Chen, et al. "The Effects of Suillus luteus Inoculation on the Diversity of Fungal Communities and Their Structures in the Soil under Pinus massoniana Located in a Mining Area." Forests 13, no. 12 (2022): 2162. http://dx.doi.org/10.3390/f13122162.

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As important decomposers and plant symbionts, soil fungal communities play a major role in remediating heavy-metal-polluted soils. However, the diversity and structures of fungal communities generally remain unclear in mining areas. This study aimed to assess the rhizospheric fungal-community composition of Masson pine (Pinus massoniana) in the lead-zinc mining area of Suxian District, Hunan Province, China. This experiment undertook the following three treatments: Masson pine inoculated with or not inoculated with Suillus luteus, and bulk soil without plants as a control. The results thereof

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23

Lei, Wei, Jianan Ni, Xueting Xia, Min Jiang, and Gang Bai. "Searching for synergistic calcium antagonists and novel therapeutic regimens for coronary heart disease therapy from a Traditional Chinese Medicine, Suxiao Jiuxin Pill." Journal of Chromatography B 1092 (August 2018): 220–27. http://dx.doi.org/10.1016/j.jchromb.2018.06.015.

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24

Song, Nixue, Dayun Lu, Gaosong Wu, et al. "Serum proteomic analysis reveals the cardioprotective effects of Shexiang Baoxin Pill and Suxiao Jiuxin Pill in a rat model of acute myocardial infarction." Journal of Ethnopharmacology 293 (July 2022): 115279. http://dx.doi.org/10.1016/j.jep.2022.115279.

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25

Aljeboory, Ali A. H., and Nazhat M. Abdlkareem Al-Zubaidi. "Loranthus Europaeus is an Alternative Medicine in Treatment of Cyst and Mouth Inflammation Resulted from Chemotherapy of Breast Cancer." International Journal of Drug Delivery Technology 10, no. 01 (2020): 183–86. http://dx.doi.org/10.25258/ijddt.10.1.32.

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The natural product continues to be important as a source of novel drugs because these drugs do not need a sophisticated instrument, cheap resources, less toxic, no resistance to them by bacteria compared with the synthetic drugs. However, the natural product will continue to be important in addition in three areas of discovery, they are a target for production by biotechnology, as source of new lead compounds of a novel chemical structure and as the active ingredients of useful treatments divided from traditional systems of folkloric medicine.1 The herb Loranthus Europaeus leaves, and fruits

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26

Sun, Yuan-long, Yi-li Yao, Mei-jun Jia, et al. "Evaluation of the efficacy and safety of Suxiao Jiuxin Pill in the treatment of stable angina: A randomized, double-blind, placebo-controlled, multi-center clinical trial." Journal of Ethnopharmacology 318 (January 2024): 116959. http://dx.doi.org/10.1016/j.jep.2023.116959.

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27

Shang, Ye, Minglei Ge, Peng Zhao, et al. "A pharmacokinetic study on twenty-one compounds in rat plasma by integrating UPLC-QQQ-MS/MS with GC-MS after oral administration of Suxiao Jiuxin pill." Arabian Journal of Chemistry 17, no. 1 (2024): 105397. http://dx.doi.org/10.1016/j.arabjc.2023.105397.

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28

Shen, Zhijie, Tiejun Chen, Bing Deng, et al. "Effects on Suxiao Jiuxin Pills in the Treatment of Patients with Acute Coronary Syndrome Undergoing Early Percutaneous Coronary Intervention: A Multicenter Randomized Double-Blind Placebo-Controlled Trial." Journal of Alternative and Complementary Medicine 26, no. 11 (2020): 1055–63. http://dx.doi.org/10.1089/acm.2020.0014.

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29

Shang, Ye, Yameng Zhu, Shuting Zhou, et al. "A UPLC-MS/MS coupled with GC-MS method for quantification of twenty-one chemical ingredients from Suxiao Jiuxin pill in multiple tissue of rat and its application to tissue distribution study." Journal of Pharmaceutical and Biomedical Analysis 252 (January 2025): 116461. http://dx.doi.org/10.1016/j.jpba.2024.116461.

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Liu, Juntao, Zhexiu Yu, Xihui Li, Ling Zhou, Ruihui Wang, and Weihua Zhang. "Tree Selection of Vernicia montana in a Representative Orchard Cluster Within Southern Hunan Province, China: A Comprehensive Evaluation Approach." Plants 14, no. 15 (2025): 2351. https://doi.org/10.3390/plants14152351.

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With the objective of identifying superior Vernicia montana trees grounded in phenotypic and agronomic traits, this study sought to develop and implement a comprehensive evaluation method which would provide a practical foundation for future clonal breeding initiatives. Using the Vernicia montana propagated from seedling forests grown in the Suxian District of Chenzhou City in southern Hunan Province, we conducted pre-selection, primary selection, and re-selection of Vernicia montana forest stands and took the nine trait indices of single-plant fruiting quantity, single-plant fruit yield, dise

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31

Davidsen, Claus, Silvio J. Pereira-Cardenal, Suxia Liu, Xingguo Mo, Dan Rosbjerg, and Peter Bauer-Gottwein. "Erratum for “Using Stochastic Dynamic Programming to Support Water Resources Management in the Ziya River Basin, China” by Claus Davidsen, Silvio J. Pereira-Cardenal, Suxia Liu, Xingguo Mo, Dan Rosbjerg, and Peter Bauer-Gottwein." Journal of Water Resources Planning and Management 141, no. 3 (2015): 08214001. http://dx.doi.org/10.1061/(asce)wr.1943-5452.0000504.

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Lu, Shun, Jie Hu, Jianhua Chen, et al. "Abstract CT053: Aumolertinib with or without chemotherapy as first line treatment in locally advanced or metastatic NSCLC with sensitizing EGFR mutations (AENEAS2)." Cancer Research 85, no. 8_Supplement_2 (2025): CT053. https://doi.org/10.1158/1538-7445.am2025-ct053.

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Abstract Introduction: Aumolertinib, a third generation selective EGFR-TKI, is standard of care for the first-line treatment in advanced or metastatic NSCLC with sensitizing EGFR mutations in China. Evidence has shown that combining EGFR-TKIs with chemotherapy can improve outcomes compared to EGFR-TKIs monotherapy. AENEAS2 (NCT04923906) is a randomized, open-label, multicenter, phase 3 study assessing the efficacy and safety of aumolertinib plus chemotherapy versus aumolertinib alone as first-line treatment in locally advanced or metastatic NSCLC with sensitizing EGFR mutations. Methods: Patie

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Huang, Lisi, Xin Du, Jianyu Weng, et al. "Comparison of the 5 Year Medical Outcome and Quality of Life of Patients with Chronic Myeloid Leukemia Treated with Imatinib or Allogeneic Transplant." Blood 126, no. 23 (2015): 2118. http://dx.doi.org/10.1182/blood.v126.23.2118.2118.

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Abstract Comparison of the 5 year Medical Outcome and Quality of Life of Patients with Chronic Myeloid Leukemia treated with Imatinib or Allogeneic Transplant Jianyu Weng1*, Lisi Huang1*, Peilong Lai1, Zesheng Lu1, Ping Wu1, Suijing Wu1, Chengwei Luo1, Wei Ling1, Chenxin Deng1, Xin Huang1, Suxia Geng1, Xin Du1? 1Department of Hematology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, P.R. China. *These authors contributed equally to this work.? Corresponding author: Xin Du, MD, Ph.D. 106. Zhongshan Er Rd, Guangzhou, 510080, P.R. China E-mail: miyadu@hotmail.com P

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Chen, Naifei, Chengfei Pu, Lingling Zhao, et al. "Abstract 1130: A phase 1 dose escalation study of GCC19CART - a novel CoupledCAR therapy for subjects with metastatic colorectal cancer." Cancer Research 83, no. 7_Supplement (2023): 1130. http://dx.doi.org/10.1158/1538-7445.am2023-1130.

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Abstract Background: Chimeric antigen receptor (CAR) T-cell therapy has shown remarkable clinical efficacy in hematologic malignancies but limited success in solid tumors. GCC19CART, the first clinical candidate from the CoupledCAR solid tumor platform, is designed to overcome the limitations of conventional CAR T-cells in solid tumor malignancies by pairing solid tumor CAR T-cells with CD19 targeting CAR T-cells to amplify proliferation and activation of the solid tumor CAR T component. GCC19CART targets guanylate cyclase-C (GCC) which is expressed in the metastatic lesions of 70%-80% of subj

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Xu, Jianming, Haiping Jiang, Yueyin Pan, et al. "Abstract CT078: First-line treatment with sintilimab (sin) vs placebo in combination with chemotherapy (chemo) in patients (pts) with unresectable gastric or gastroesophageal junction (G/GEJ) cancer: Final overall survival (OS) results from the randomized, phase III ORIENT-16 trial." Cancer Research 83, no. 8_Supplement (2023): CT078. http://dx.doi.org/10.1158/1538-7445.am2023-ct078.

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Abstract Background: The phase III ORIENT-16 trial evaluated sin (a PD-1 inhibitor) versus placebo plus chemo as first-line (1L) treatment in pts with advanced G/GEJ adenocarcinoma. Sin+chemo previously showed a significant improvement in OS vs chemo in pts with PD-L1 combined positive score (CPS) ≥5 (HR 0.660; 95% CI 0.505-0.864; P=0.0023) and in all pts (HR 0.766; 95% CI 0.626-0.936; P=0.0090), with a median follow-up of 18.8 months (m) at interim analysis (Xu, et al. Ann Oncol 2021). Here we report the results from the final analysis (NCT03745170). Methods: This double-blind, phase III tria

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Yang, Yunpeng, Yuanyuan Zhao, Wenfeng Fang, et al. "Abstract CT227: Anti-LAG-3 antibody LBL-007 in combination with anti-PD-1 antibody toripalimab, in patients with advanced malignant tumors: A phase Ib/II, open-label, multicenter, dose escalation/expansion study." Cancer Research 84, no. 7_Supplement (2024): CT227. http://dx.doi.org/10.1158/1538-7445.am2024-ct227.

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Abstract Background: Dual inhibition of PD-1 and LAG-3 may have the potential to increase the immune response against tumor growth synergistically. Here we report the preliminary safety and efficacy results of LBL-007 (an anti-LAG-3 antibody) in combination with toripalimab (an anti-PD-1 antibody) in patients with advanced malignant tumors. Methods: Patients with advanced malignant tumors, including but not limited to nasopharyngeal carcinoma (NPC), non-small cell lung cancer (NSCLC), esophageal squamous cell carcinoma (ESCC), and head and neck squamous carcinoma (HNSCC), with or without prior

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Yang, Rongzhi, Tianliu Huang, Weiwei Song, Zixian An, Zhongxiong Lai, and Shengcai Liu. "Identification of WRKY gene family members in amaranth based on a transcriptome database and functional analysis of AtrWRKY42-2 in betalain metabolism." Frontiers in Plant Science 14 (December 5, 2023). http://dx.doi.org/10.3389/fpls.2023.1300522.

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IntroductionWRKY TFs (WRKY transcription factors) contribute to the synthesis of secondary metabolites in plants. Betalains are natural pigments that do not coexist with anthocyanins within the same plant. Amaranthus tricolor (‘Suxian No.1’) is an important leaf vegetable rich in betalains. However, the WRKY family members in amaranth and their roles in betalain synthesis and metabolism are still unclear.MethodsTo elucidate the molecular characteristics of the amaranth WRKY gene family and its role in betalain synthesis, WRKY gene family members were screened and identified using amaranth tran

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Asila, CHORIYEVA. "SAHIFANI VARAQLAGAN SARI, TUBSIZLIK KISHIGA SHE"RIYATNING MOHIYATINI ANGLATADI." January 15, 2023. https://doi.org/10.5281/zenodo.8265353.

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Ushbu maqolada o'zbek va rus shoiri Aleksandr Arkadevich Faynbergning hayoti va shoirning oxirgi yillaridagi kechinmalari zamondoshlari tilidan hikoya qilingan. Maqolani o'qish jarayonida shoirning vataniga sadoqati, fel-atvoridagi odamiylik fazilatlariga yuksak baho berish mumkin. A.Faynberg bilan suxbatda bo'lgan kishilarning fikricha, shoirning hayoti go'yoki bir kitob-u, varaqlaganingiz sari uning tub mohiyati ochiladi. 

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Li, Sa, Jiaguo Zhan, Yucheng Wang, et al. "Suxiao Jiuxin Pill attenuates acute myocardial ischemia via regulation of coronary artery tone." Frontiers in Pharmacology 14 (May 10, 2023). http://dx.doi.org/10.3389/fphar.2023.1104243.

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Suxiao Jiuxin Pill (SJP) is a well-known traditional Chinese medicine drug used to manage heart diseases. This study aimed at determining the pharmacological effects of SJP in acute myocardial infarction (AMI), and the molecular pathways its active compounds target to induce coronary artery vasorelaxation. Using the AMI rat model, SJP improved cardiac function and elevated ST segment. LC-MS and GC-MS detected twenty-eight non-volatile compounds and eleven volatile compounds in sera from SJP-treated rats. Network pharmacology analysis revealed eNOS and PTGS2 as the key drug targets. Indeed, SJP

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Duan, Xin, Likun Zhou, Taixiang Wu, et al. "Chinese herbal medicine suxiao jiuxin wan for angina pectoris." Cochrane Database of Systematic Reviews, January 23, 2008. http://dx.doi.org/10.1002/14651858.cd004473.pub2.

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Sun, Li, Nannan Li, Huilin Li, Qingshan Zhang, Shuai Bao, and Xiaolu Li. "A Potential Therapeutic Effect of Suxiao Jiuxin Pills in Treating Postacute Sequelae of COVID‐19: Case Report." Case Reports in Infectious Diseases 2024, no. 1 (2024). http://dx.doi.org/10.1155/crdi/4713552.

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Postacute Sequelae of COVID‐19 Cardiovascular Syndrome (PASC‐CVS) refers to a broad spectrum of cardiovascular symptoms that manifest four weeks or more after infection with COVID‐19, which cannot be diagnosed as cardiovascular disease through standard examinations. Common symptoms include exercise intolerance and tachycardia, alongside persistent issues such as chest pain, chest tightness, and difficulty breathing. PASC‐CVS significantly affects patients’ quality of life; however, effective treatments for this condition are currently lacking. In this report, we present two cases of PASC‐CVS p

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Guo, QX, J. Zhang, YQ Li, and GF Zhang. "Study on anti-atherosclerotic effect of suxiao jiuxin pill and its mechanism." African Journal of Traditional, Complementary and Alternative Medicines 11, no. 1 (2013). http://dx.doi.org/10.4314/ajtcam.v11i1.14.

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Li, Yiping, Ruixia Lu, Zhenchao Niu, Dan Wang та Xiaolong Wang. "Suxiao Jiuxin Pill Alleviates Myocardial Ischemia-Reperfusion Injury Through the ALKBH5/GSK3β/mTOR Pathway". SSRN Electronic Journal, 2022. http://dx.doi.org/10.2139/ssrn.4206802.

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Li, Yiping, Ruixia Lu, Zhenchao Niu, Dan Wang та Xiaolong Wang. "Suxiao Jiuxin Pill alleviates myocardial ischemia–reperfusion injury through the ALKBH5/GSK3β/mTOR pathway". Chinese Medicine 18, № 1 (2023). http://dx.doi.org/10.1186/s13020-023-00736-6.

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Abstract Background Many studies have shown effective protection from myocardial ischemia–reperfusion injury (MIRI) in animal models, but few, if any, treatments have yielded a substantial reduction in clinical. Several studies showed significant therapeutic effects for the Chinese patent medicine Suxiao Jiuxin Pill (SJP) in MIRI, although the specific molecular mechanisms remain undefined. Recently, increasing evidence indicates an important role for m6A modification in autophagy regulation in MIRI, and SJP has not been investigated in this regard. Methods In vivo experiments were performed i

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Wang, Dongyuan, Dan Wang, Qipeng Jin, and Xiaolong Wang. "Suxiao Jiuxin Pill Alleviates Myocardial Ischemia/Reperfusion-Induced Autophagy via miR-193a-3p/ALKBH5 Pathway." Phytomedicine, January 2024, 155359. http://dx.doi.org/10.1016/j.phymed.2024.155359.

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Lu, Zhiqiang, Yanjun Zhang, Pengwei Zhuang, et al. "Protective effect of Suxiao jiuxin pill, a traditional Chinese medicine, against acute myocardial ischemia in dogs." BMC Complementary and Alternative Medicine 15, no. 1 (2015). http://dx.doi.org/10.1186/s12906-015-0908-9.

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Liao, Jingyu, Yuhao Zhang, Chi Ma, Gaosong Wu, and Weidong Zhang. "Microbiome-metabolome reveals that the Suxiao Jiuxin pill attenuates acute myocardial infarction associated with fatty acid metabolism." Journal of Ethnopharmacology, April 2023, 116529. http://dx.doi.org/10.1016/j.jep.2023.116529.

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Yin-Kai, Chao. "P153 DEVELOPMENT OF A NOMOGRAM FOR THE PREDICTION OF INTERVAL METASTASES AFTER CHEMORADIOTHERAPY IN PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA." Diseases of the Esophagus 32, Supplement_2 (2019). http://dx.doi.org/10.1093/dote/doz092.153.

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Abstract Aim To develop a nomogram for predicting interval metastases during chemoradiotherapy(CRT) in esophageal squamous cell carcinoma(ESCC) patients. Background&Methods During CRT for esophageal cancer, some patients develop systemic metastasis. Nomograms incorporating multiple prognostic factors are useful for individualized estimation of survival in cancer patients. However, nomograms for the prediction of interval metastases after CRT in patients with esophageal cancer are scarce. We retrospectively reviewed the records of 358 ESCC patients who underwent CRT as first line treatment.

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Qi, Jian-yong, Dong-yuan Kang, Juan Yu, and Min-zhou Zhang. "Suxiao Jiuxin Pills Prevent Ventricular Fibrillation from Inhibiting L-type Calcium Currents CaV1.2 in vivo and in vitro." Chinese Journal of Integrative Medicine, November 3, 2022. http://dx.doi.org/10.1007/s11655-022-3623-7.

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Chen, Daqiu, Yanqing Wu, Yixing Chen, et al. "Exploration of the molecular targets and mechanisms of suxiao xintong dropping pills for myocardial infarction by network pharmacology method." Bioscience Reports 41, no. 8 (2021). http://dx.doi.org/10.1042/bsr20204211.

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Abstract Background: Suxiao Xintong dropping pills (SXXTDP), a traditional Chinese medicine, is widely applied for treating myocardial infarction (MI). However, its therapy mechanisms are still unclear. Therefore, this research is designed to explore the molecular mechanisms of SXXTDP in treating MI. Methods: The active ingredients of SXXTDP and their corresponding genes of the active ingredients were retrieved from the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database. MI-related genes were identified via analyzing the expression profiling data (accession number: GSE97320). G

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