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Статті в журналах з теми "Syndrome AIDP"

Автор: Grafiati

Опубліковано: 7 червня 2025

Оновлено: 2 серпня 2025

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1

International, Journal of Medical Science and Innovative Research (IJMSIR). "Atypical Presentation of Acute Inflammatory Demyelinating Polyneuropathy (AIDP) with Psychomotor Symptoms in a Young Male: A Case Report." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 1 (2024): 22–25. https://doi.org/10.5281/zenodo.15364529.

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<strong>Abstract</strong> Acute Inflammatory Demyelinating Polyneuropathy (AIDP) is acknowledged as the most prevalent variant of Guillain-Barre syndrome, though diagnosing it can be intricate. Patients often exhibit symptoms that might be misconstrued as psychosomatic, adding complexity to the diagnostic process. This case involves a patient who presented with insomnia, tremors, and restlessness, without any associated dreams. Unlike the conventional presentation of AIDP, this atypical manifestation underscores the challenges in identifying Guillain-Barre syndrome. The case report delves into

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2

Baslo, Sezin Alpaydin, Metin Dedei Daryan, Mahir Yusifov, et al. "Prolonged Median Motor Distal Latency: What If not Carpal Tunnel Syndrome but Acute Inflammatory Demyelinating Polyradiculoneuropathy?" Neurological Sciences and Neurophysiology 41, no. 4 (2024): 217–22. https://doi.org/10.4103/nsn.nsn_117_24.

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ABSTRACT Introduction: The wrist is the only segment where both sensory and motor conduction of the same nerve can be studied through routine nerve conduction studies. This study aims to evaluate how two diseases with different pathophysiologies, carpal tunnel syndrome (CTS) and acute inflammatory demyelinating polyradiculoneuropathy (AIDP), differ in terms of median nerve conduction at the wrist. Materials and Methods: Patients hospitalized and diagnosed as having Guillain–Barré syndrome between 2013 and 2021 were screened from the hospital database. Electrodiagnostic subtype classification w

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3

Gasemaltayeb, Raed. "An Atypical Clinical Presentation of Acute Inflammatory Demyelinating Polyradiculoneuropathy." Saudi Journal of Medicine 8, no. 07 (2023): 397–98. http://dx.doi.org/10.36348/sjm.2023.v08i07.005.

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Acute inflammatory demyelinating polyradiculoneuropathy (AIDP), also known as Guillain-Barre syndrome (GBS), is an autoimmune disease that is typically present as a progressive ascending weakness, with subtle or no sensory findings, and reduced or absent deep tendon reflexes. In this case report I am presenting a patient who presented with an atypical clinical feature of AIDP in the form of a descending rather than ascending weakness, highlighting the importance of considering AIDP as a potential diagnosis in such atypical presentations.

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Reiter-Campeau, S., and D. Gendron. "P.101 A-waves on electrodiagnostic studies in axonal and demyelinating cases of Guillain-Barré Syndrome (GBS)." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 49, s1 (2022): S35. http://dx.doi.org/10.1017/cjn.2022.196.

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Background: A-waves are lesser-known late responses of debated clinical significance, seen in routine motor nerve conduction studies (NCS). They are proposed to be a sensitive marker of demyelination and an early finding in acute demyelinating polyradiculoneuropathy (AIDP). We hypothesized that the presence and distribution of A-waves are discriminative markers in differentiating AIDP from axonal variants of Guillain-Barré Syndrome (GBS). Methods: We identified patients diagnosed with demyelinating and axonal forms of GBS at the Montreal Neurological Institute between 2016 and 2021. Clinical a

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5

Varatharajan, Aaran. "Acute Guillain-Barré Syndrome After Sacroiliac Joint Fusion." Pain Medicine Case Reports 8, no. 4 (2024): 137–42. http://dx.doi.org/10.36076/pmcr.2024.8.137.

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BACKGROUND: Guillain-Barré syndrome (GBS), also called acute inflammatory demyelinating polyradiculopathy (AIDP), is one of the most common causes of acute, acquired weaknesses. GBS is an acute immune-mediated polyneuropathy that presents with progressive weakness of the arms or legs. GBS presents after infection; however, there are few reports that describe acute GBS after chronic pain procedures. CASE REPORT: A 70-year-old man with a past medical history of spinal stenosis status post anterior cervical discectomy and fusion, sacroiliac joint (SIJ) dysfunction status post SIJ fusion presented

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6

Hossain, SM Monowar, Zahed Ali, Mohammad Motiur Rahman, Md Aolad Hossain, Pallab Kanti Saha, and Sultana Nadira Rahman. "Electrophysiological patterns in patient with Guillain-Barre syndrome." BIRDEM Medical Journal 12, no. 1 (2021): 16–21. http://dx.doi.org/10.3329/birdem.v12i1.57220.

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Background: Guillain-Barre syndrome (GBS) is an acute, frequently severe and fulminant polyradiculoneuropathy that is autoimmune in nature. Incidence and predominant subtypes of GBS differ geographically. Electrophysiology has important role in subtyping GBS. This study aimed to evaluate the electrophysiological findings in patient of GBS. Methods: This was a hospital based cross-sectional descriptive study and conducted at the Department of Neurology in Sir Salimullah Medical College & Mitford Hospital, Dhaka and National Institute of Neurosciences and Hospital, Dhaka during July 20

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7

Debnath, Bithi, Sudipta Kumer Mukherjee, Monsur Ahmed, et al. "Children with Guillain-Barre Syndrome: A Comparison between AIDP and AMAN variants among Patients admitted in a Tertiary Care Hospital." Bangladesh Journal of Neurosurgery 11, no. 2 (2022): 94–100. http://dx.doi.org/10.3329/bjns.v11i2.61452.

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Background: Guillain-Barre syndrome (GBS) is the leading cause of acute flaccid paralysis in children. This study was aimed to compare the clinical spectrum and shortterm outcome of children with acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and acute motor axonal neuropathy (AMAN) subtypes of GBS in children. Methods: The study was a prospective cohort study done in a tertiary neurology hospital for 3 years. Children under 18 years of age fulfilling the Brighton diagnostic criteria for GBS were enrolled in the study. Based on the nerve conduction study, patients were subclass

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8

YILDIZ, Mehmet, Halit FİDANCI, Gülçin ORTAÇ, Şencan BUTURAK, and Zülfikar ARLIER. "Comparison of ulnar, median, and sural sensory nerve conduction studies between demyelinating and axonal forms of Guillain-Barré Syndrome." Archives of Current Medical Research 4, no. 2 (2023): 70–77. http://dx.doi.org/10.47482/acmr.1170798.

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Background: Guillain-Barré syndrome (GBS) is an important neurological disease that can cause disability. Axonal GBS and acute inflammatory demyelinating polyradiculoneuropathy (AIDP) are two important subgroups. Methods: Patients with clinical and electrodiagnostic features compatible with GBS were included in this retrospective study. The patients were divided into two groups neurophysiologically as Axonal GBS and AIDP. Medical research council (MRC) scores of the patients' muscles, median / ulnar / posterior tibial / peroneal / sural nerve conduction study findings were included in th

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9

OSHOMOJI, OLAWALE ISREAL, Oluwafemi Temitayo ILESANMI, Samuel Oluwaseun SEMUDARA, Johnson Olasunkanmi AJIROBA, Anthony Ibukun ANUKWU, and Adebori Andrew SEFINNI. "PHYSIOTHERAPY MANAGEMENT OF AIDP GUILLAIN-BARRÉ SYNDROME VARIANT IN A TERTIARY HOSPITAL IN SOUTH-WEST NIGERIA: A CASE REPORT." International Journal of Medical Science and Dental Health 10, no. 07 (2024): 55–65. http://dx.doi.org/10.55640/ijmsdh-10-07-07.

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Guillain-Barré Syndrome (GBS) is an acute neurological condition marked by swift muscular weakening, with the most prevalent form being the Acute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP) variety. This case report provides a comprehensive account of the physiotherapy treatment of a 35-year-old patient diagnosed with Acute Inflammatory Demyelinating Polyneuropathy (AIDP) in a tertiary hospital in South-West Nigeria. After contracting a gastrointestinal infection, the patient developed a gradual loss of strength in their limbs and paralysis of the facial muscles on both sides of t

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10

Sullo, Federica, Milena Motta, Pierluigi Smilari, Luigi Rampello, Filippo Greco, and Piero Pavone. "Acute Motor Axonal Neuropathy in a 5-Month-Old Child." Journal of Pediatric Neurology 18, no. 03 (2019): 171–74. http://dx.doi.org/10.1055/s-0039-1698816.

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AbstractGuillain–Barré syndrome (GBS) is an acute inflammatory polyneuropathy characterized by rapidly progressive, essentially symmetric weakness and areflexia in a previously otherwise healthy child. It is the most common cause of acute flaccid paralysis in children, and its reported incidence is 1 to 2/100,000 population. Prior infection is a well-established predating event in GBS. The commonly recognized variants of GBS are acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), acute motor sensory axonal neuropathy, and Miller–Fisher syndrome. AIDP i

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Castro, Vinicius Furtado da Silva, Roberto Teodoro Gurgel de Oliveira, João Daniel Lima dos Santos, et al. "The sural-sparing pattern in clinical variants and electrophysiological subtypes of Guillain-Barré syndrome." Arquivos de Neuro-Psiquiatria 82, no. 04 (2024): 001–7. http://dx.doi.org/10.1055/s-0044-1785692.

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Abstract Background Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis worldwide and can be classified into electrophysiological subtypes and clinical variants. Objective This study aimed to compare the frequency of the sural-sparing pattern (SSP) in subtypes and variants of GBS. Methods This retrospective cohort study analyzed clinical and electrophysiological data of 171 patients with GBS hospitalized in public and private hospitals of Natal, Rio Grande do Norte, Brazil, between 1994 and 2018; all cases were followed up by the same neurologist in a reference ne

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12

Roy, Chinnu, Jobin Kunjumon Vilapurathu, and Dhanya Paul. "Case Report on Guillain Barre Syndrome: Acute Inflammatory Demyelinating Polyneuropathy." International Journal of Research and Review 8, no. 9 (2021): 548–50. http://dx.doi.org/10.52403/ijrr.20210969.

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Guillain Barre Syndrome (GBS) is an autoimmune disorder which affects the peripheral nervous system. It is a rare disorder affects in 1 per million people in year. It is characterized by symmetrical, progressive limb weakness and tingling. Case Report: A 53 year old male patient was presented with insidious onset of difficulty in moving right upper and lower limbs as well as gradual weakness of left limbs, and breathing difficulty, known case of diabetics’ mellitus and hypertension. Nerve conduction study shows suggest axonopathy; Acute Inflammatory Demyelinating Polyneuropathy (AIDP) is ident

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13

Ozdemir, Hasan Huseyin. "Analysis of the albumin level, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio in Guillain-Barré syndrome." Arquivos de Neuro-Psiquiatria 74, no. 9 (2016): 718–22. http://dx.doi.org/10.1590/0004-282x20160132.

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ABSTRACT The purpose of this study was to investigate the prognostic value of the pretreatment and post-treatment albumin level, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) in subtypes of Guillain-Barré syndrome (GBS). A retrospective analysis of 62 patients with GBS treated between 2011 and 2015 in Dicle University Hospital, Turkey, was carried out. The pretreatment and post-treatment albumin, NLR, and PLR were documented, together with acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy, motor sensory axonal neuropathy, and

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14

Voitenkov, Vladislav B., Natalia V. Skripchenko, Andrey V. Klimkin, and Stepan G. Grigoriyev. "Neurophysiology of Guillain-Barré syndrome in children." Pediatrician (St. Petersburg) 9, no. 4 (2018): 50–57. http://dx.doi.org/10.17816/ped9450-57.

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Our aim was to evaluate sensitivity and specificity of conduction studies parameters for prognosis and differential diag nosis in children with acute motor axonal neuropathy (AMAN) & acute inflammatory demyelinating polyneuropathy (AIDP). Methods. 40 children were included: 20 healthy controls (7-14 years) and 20 patients (8-15 years) with AIDP or AMAN. All underwent conduction studies on 3-7 day since the clinical symptoms onset. We registered and evaluated motor conduction velocity, compound muscle action potential (CMAP) amplitude of nn. tibialis, peroneus, medianus, ulnaris; sens

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15

Khazaei, Mojtaba, Fatemeh Ghasemi, Mehrdokht Mazdeh, Elham Khanlarzadeh, and Masoud Ghiasian. "Epidemiologic and Clinical Characteristics of Guillain-Barré Syndrome in Patients Referred to Sina Hospital in Hamadan in 2018." Epidemiology and Health System Journal 9, no. 4 (2022): 150–54. http://dx.doi.org/10.34172/ehsj.2022.27.

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Background and aims: Guillain-Barré syndrome (GBS) has several types, some of which damage myelin and some others cause axonal damage. Detecting the type of GBS is important in determining the type of treatment and its prognosis. This study was conducted to investigate the epidemiological characteristics of GBS and its variants in patients referred to Sina hospital in Hamadan, Iran, in 2018. Methods: In this cross-sectional study, 51 patients who were admitted to Sina hospital and diagnosed with GBS in 2018 were examined. Demographic data, GBS type, disease outcomes, and pre-clinical and clini

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16

Shrivastava, Manisha, Shah Nehal, and Navaid Seema. "Guillain–Barre syndrome." Indian Journal of Medical Research 145, no. 2 (2017): 203–8. https://doi.org/10.4103/ijmr.ijmr_995_14.

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Background & objectives: Guillain–Barre syndrome (GBS) is an autoimmune disease and a recognized cause of generalized progressive paralysis worldwide. The present study was aimed to document the clinical findings, demographics and seasonal variations amongst the patients with GBS during the hospital stay. Methods: A retrospective analysis of 66 referred cases diagnosed as GBS was conducted. Medical records and the data related to age, sex, antecedent illness, duration of symptoms before admission, muscle power graded by the Medical Research Council scale, functional scores, details of Inte

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17

Putri, Gyang Hanandita Gusti, Nectarine Natasya Regitta Yasmin, and Shahdevi Nandar Kurniawan. "GUILLAIN-BARRÉ SYNDROME." JPHV (Journal of Pain, Vertigo and Headache) 4, no. 2 (2023): 46–50. http://dx.doi.org/10.21776/ub.jphv.2023.004.02.4.

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Guillain-Barré Syndrome (GBS) is an infection-preceded autoimmune disease attacking myelin sheath of neurons through molecular mimicry, causing neuron demyelination and conduction disruption. GBS is classified into four subtypes: Acute Inflammatory Demyelinating (AIDP), Acute Motor Axonal Neuropathy (AMAN), Acute Motor Sensory Axonal Neuropathy (AMSAN), and Miller Fisher Syndrome. It affects spinal radix which resulted in polyneuropathy, showing mainly symptoms of ascending paresis of the extremity and areflexia. Cerebrospinal fluid evaluation is essential to distinguish GBS from its vast diff

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Dalai, Siba Prasad, Shobhitendu Kabi, Nikhil R. Arve, and Vujwal R. Kakollu. "Tubercular Meningitis with Acute Inflammatory Demyelinating Polyneuropathy—Trigger or Chance." Journal of Neurosciences in Rural Practice 10, no. 03 (2019): 545–47. http://dx.doi.org/10.1055/s-0039-1697567.

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AbstractTuberculosis being a global pandemic causes an array of neurological presentations ranging from tuberculoma, meningitis, radiculomyelitis, brain abscess, and so on.Association of Guillain-Barre syndrome with tuberculosis has been reported five to six times in the past. The authors report a case of a young female with tubercular meningitis on antitubercular therapy and steroids who went on to develop acute areflexic quadriparesis and diagnosed as a case of acute motor sensory axonal neuropathy variety of acute inflammatory demyelinating polyneuropathy (AIDP) who responded positively to

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Voinov, V. A., R. A. Gapeshin, E. S. Tarabanova, A. A. Iakovlev, K. S. Karchevskii, and O. V. Isaulov. "EXPERIENCE IN THE USE OF PLASMAPHERESIS IN ACUTE INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY GUILLAIN – BARRE SYNDROME IN THE PATIENT WITH CHRONIC HEPATITIS C VIRUS INFECTION AND TYPE 2 DIABETES MELLITUS." Scientific Notes of the I. P. Pavlov St. Petersburg State Medical University 25, no. 3 (2018): 96–103. http://dx.doi.org/10.24884/1607-4181-2018-25-3-96-103.

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Acute inflammatory demyelinating polyneuropathy Guillain – Barre syndrome (AIDP-GB) – acquired immune mediated disease with acute onset characterized by the development of peripheral tetraparesis due to immune system attack to peripheral nerves and spinal roots. This article describes the case report of AIDP-GB development in the patient with hepatitis C and type 2 diabetes mellitus. The patient was treated with course of plasmapheresis and subsequent course of intravenous immunoglobulin (IVIG) for increasing the effectiveness of therapy. During the therapy, there was a significant improvement

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Breville, Gautier, Agustina M. Lascano, Pascale Roux-Lombard, Nicolas Vuilleumier, and Patrice H. Lalive. "Interleukin 8, a Biomarker to Differentiate Guillain-Barré Syndrome From CIDP." Neurology - Neuroimmunology Neuroinflammation 8, no. 5 (2021): e1031. http://dx.doi.org/10.1212/nxi.0000000000001031.

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ObjectiveTo determine whether CSF interleukin 8 (IL-8) concentration can help to distinguish Guillain-Barré syndrome (GBS) from chronic inflammatory demyelinating polyneuropathy (CIDP) at the initial stage of the disease.MethodsWe performed retrospective immunoassay of IL-8 in CSF, collected at the University Hospitals of Geneva between 2010 and 2018, from patients diagnosed with GBS (n = 45) and with CIDP (n = 30) according to the Brighton and European Federation of Neurological Societies/Peripheral Nerve Society criteria by a physician blinded to biological results.ResultsCSF IL-8 was higher

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Munasinghe, Hasini, Sudath Gunasekara, Kamal Gunarathne, et al. "Sural nerve involvement in patients with acute inflammatory demyelinating polyneuropathy variant of Guillain-Barre syndrome with sural sparing at initial presentation." Sri Lanka Journal of Neurology 10, no. 2 (2023): 50–54. http://dx.doi.org/10.4038/sljon.v10i2.163.

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Introduction: Neurophysiological testing is a valuable tool in the diagnosis of Guillain-Barre syndrome (GBS). Sural sparing is a usual feature of acute inflammatory demyelinating polyneuropathy (AIDP) type GBS. However, sural involvement has been reported in later stages of GBS. It is important to identify patterns of sural nerve involvement to differentiate GBS from its mimickers and to stage the disease. This research aimed to detect the pattern of sural nerve involvement in AIDP-GBS cases with normal electrophysiological responses in the sural nerve at the beginning.Objectives: To determin

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Kumar, Mritunjai, Ashutosh Tiwari, Shakti Kumar, and Rajni Singh. "Dose–Effect Relationship of Motor Nerve Inexcitability on Outcome in Guillain–Barré Syndrome: A Prospective Cohort Study." Annals of Indian Academy of Neurology 26, no. 6 (2023): 936–42. http://dx.doi.org/10.4103/aian.aian_641_23.

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Objective: One or more inexcitable motor (IM) nerves are common during electrodiagnostic (EDx) study in Guillain–Barré syndrome (GBS). This study assessed the dose–effect relationship of IM nerves on outcome in patients with acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor and/or sensory axonal neuropathy (AMAN and AMSAN). Materials and Methods: Eighty-eight GBS patients admitted during May 2018–June 2023 underwent detailed clinical evaluation and EDx study. Admission and follow-up disability were assessed on a 0–10 Clinical Grading Scale (CGS). Outcome was recovery at 6

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Ravi Sankar, Parvathy. "A case report describing a rare presentation of Acute Inflammatory Demyelinating Polyradiculopathy (AIDP)." Journal of Clinical Research and Reports 4, no. 4 (2020): 01–02. http://dx.doi.org/10.31579/2690-1919/089.

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Background: AIDP (Acute Inflammatory Demyelinating Polyradiculopathy) commonly presents as bilateral lower extremity weakness and areflexia with albuminocytologic dissociation on CSF findings. Sensory symptoms are not prominent presenting features in patients. However, Bulbar and Miller Fisher variants of AIDP are very rare. This case report highlights the unique presentation where unilateral facial nerve palsy along with perioral numbness and decreases taste sensation was the presenting symptom. Case presentation: A 33-year-old male with a past medical history of rhabdomyosarcoma s/p resectio

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Courant, V., M. Silva, and S. Grewal. "AB1102 A RARE CASE OF ACUTE INFLAMMATORY DEMYELINATING POLYRADICULOPATHY FOLLOWING THE SECOND DOSE OF PFIZER COVID-19 VACCINE." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1669.1–1669. http://dx.doi.org/10.1136/annrheumdis-2022-eular.1028.

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BackgroundWe present a case of a 36 year-old female who developed Acute Immune-mediated Demyelinating Polyneuropathy (AIDP) after receiving the second dose of Pfizer COVID-19 vaccine.ObjectivesTo report a rare auto-immune complication of COIVD-19 vaccination. To educate and inform physicians about the approach to diagnosing AIDP and narrowing down its etiology.MethodsCase report and literature reviewResultsA 36 year-old female with no significant past medical history presented to the hospital with progressive bilateral paresthesia. She started to experience numbness and tingling sensation in h

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Yosha-Orpaz, Naama, Sharon Aharoni, Malcolm Rabie, and Yoram Nevo. "Atypical Clinical Presentations of Pediatric Acute Immune-Mediated Polyneuropathy." Journal of Child Neurology 34, no. 5 (2019): 268–76. http://dx.doi.org/10.1177/0883073818825213.

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Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis in children. During the acute phase, the disorder can be life-threatening by involving the respiratory muscles and the autonomic nervous system. Nevertheless, the prognosis is good, and most children achieve full recovery. The aim of this study was to characterize the clinical and electrophysiologic findings in children with Guillain-Barré syndrome referred to a tertiary center in Israel. A retrospective database review from 2009 to 2015 identified 39 children. Data on clinical presentation, respiratory complicat

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Finsterer, Josef. "Triggers of Guillain–Barré Syndrome: Campylobacter jejuni Predominates." International Journal of Molecular Sciences 23, no. 22 (2022): 14222. http://dx.doi.org/10.3390/ijms232214222.

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Guillain–Barré syndrome (GBS) is a rare immune-mediated acute polyradiculo-neuropathy that typically develops after a previous gastrointestinal or respiratory infection. This narrative overview aims to summarise and discuss current knowledge and previous evidence regarding triggers and pathophysiology of GBS. A systematic search of the literature was carried out using suitable search terms. The most common subtypes of GBS are acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor axonal neuropathy (AMAN). The most common triggers of GBS, in three quarters of cases, are previous

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Tan, Cheng-Yin, Mohd Azly Yahya, Khean-Jin Goh, and Nortina Shahrizaila. "Nerve Ultrasound Score in Chronic Inflammatory Demyelinating Polyneuropathy." Medicina 59, no. 4 (2023): 747. http://dx.doi.org/10.3390/medicina59040747.

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Background and Objectives: Studies have suggested that, by applying certain nerve ultrasound scores, demyelinating and axonal polyneuropathies can be differentiated. In the current study, we investigated the utility of ultrasound pattern sub-score A (UPSA) and intra- and internerve cross-sectional area (CSA) variability in the diagnostic evaluation of demyelinating neuropathies. Materials and Methods: Nerve ultrasound was performed in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) and acute inflammatory demyelinating polyneuropathy (AIDP) and compared to patients with a

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Tagaloa, Eneti, Frederick Venter, Li Liang, et al. "A Rare Case of Guillain-Barré Syndrome With Severe Pandysautonomia." Journal of Investigative Medicine High Impact Case Reports 9 (January 2021): 232470962110195. http://dx.doi.org/10.1177/23247096211019558.

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Acute pandysautonomia is a rare disorder characterized by autonomic failure affecting sympathetic, parasympathetic, and enteric functions. We present a case of acute inflammatory demyelinating polyneuropathy (AIDP) with severe pandysautonomia in a young, otherwise healthy, female who presented with gastrointestinal symptoms and sensory demyelinating polyneuropathy, which progressively worsened and subsequently developed bladder dysfunction and orthostatic hypotension. We discuss the challenges with diagnostic workup as well as the challenges we encountered as part of the management.

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Jamshaid Iqbal, Abdul Hameed Khan, Sarah Azam, et al. "OUTCOME OF PLEX IN GUILLAIN–BARRÉ SYNDROME PATIENTS TREATED BEFORE AND AFTER 7 DAYS OF SYMPTOMS ONSET." Insights-Journal of Health and Rehabilitation 2, no. 2 (Health & Rehab) (2024): 209–14. https://doi.org/10.71000/ijhr137.

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Background: Guillain-Barré Syndrome (GBS) is an acute, immune-mediated polyneuropathy that often follows infections, characterized by varying degrees of motor weakness, sensory impairment, and autonomic dysfunction. The disease has multiple subtypes, including Acute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP) and Acute Motor Axonal Neuropathy (AMAN), with diverse functional outcomes. Plasma exchange (PLEX) has emerged as a cost-effective and efficient therapeutic option in resource-limited settings, but its impact on various subtypes and functional outcomes requires further explor

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Sharma, Anmol, Naveen Reddy, and Jitender Sharma. "Case of post-dengue AIDP with treatment-related fluctuations." Indian Journal of Case Reports 10, no. 3 (2024): 85–87. http://dx.doi.org/10.32677/ijcr.v10i3.4401.

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Cases of dengue fever have been increasing globally and so are the encounters with its rare presentations. Although known to involve central nervous system, dengue-related Guillian Barre syndrome (GBS) is a rare manifestation that has been seldom documented. A clinical challenge with early diagnosis, specific and supportive management, and active prognostication as key pillars toward effective management. We present the case of a 54-year-old man with post-dengue GBS with treatment fluctuations successfully managed at our center.

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Kiraz, Mustafa, Abdullah Yılgör, Aysel Milanlıoğlu, Vedat Çilingir, Aydın Çağaç, and Sibel Özkan. "Clinical subtypes, seasonality, and short-term prognosis of Guillain-Barré syndrome in an Eastern city of Turkey." Neurology Asia 27, no. 4 (2022): 937–44. http://dx.doi.org/10.54029/2022wak.

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Background & Objective: This study aimed to analyze the frequency Guillain-Barré syndrome (GBS) subtypes and their relationship with clinical characteristics, seasonal variations and early prognosis in Van City, Turkey. Methods: Patients with GBS who were admitted between January 2007 and December 2017 and diagnosed with acute inflammatory demyelinating neuropathy (AIDP), acute motor axonal neuropathy (AMAN) or acute motor sensory axonal neuropathy (AMSAN) were reviewed. Demographics, season of clinical onset, history and type of preceding infection, the Hughes Disability Score (HDS) at ad

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Rafique, Muhammad, Sharmeen Nasir, Zareen Qasmi, and Waseem Jamalvi. "Clinical Profile and Predictors of Outcome of Guillain Barre Syndrome Variants among Children Admitted in the Pediatric Department of a Tertiary Care Hospital, Karachi." National Journal of Health Sciences 8, no. 3 (2023): 117–22. http://dx.doi.org/10.21089/njhs.83.0117.

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Background: Guillain Barre Syndrome (GBS) is one of the leading cause of Acute Flaccid Paralysis presenting in pediatric emergency, marking incidents in Asian countries as 3-4 per 100, 000 population. To improve outcome, an accurate and early recognition of predictors of bad prognosis is required. Objective: To identify requirement of intensive monitoring and aggressive treatment to help the health system in decreasing morbidity and mortality associated with Guillain Barre Syndrome. Materials and Methods: This is a cross-sectional study, conducted at Dr. RKMP Civil Hospital Karachi. Medical re

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Singh, Anshu Man, Vinayak M. Sawardekar, Amit Jaiswal, and Maithilee M. Kale. "Clinical, laboratory, and electrophysiological presentations and treatment modalities in Guillain–Barré syndrome: A prospective study." Journal of Internal Medicine of India 17, no. 1 (2023): 7–12. https://doi.org/10.4103/upjimi.upjimi_14_24.

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INTRODUCTION: Guillain–Barré syndrome (GBS) is a rare autoimmune disorder causing acute inflammatory demyelinating polyneuropathy (AIDP), leading to muscle weakness, paralysis, and respiratory failure. MATERIALS AND METHODS: This single-center, prospective study was performed in the department of medicine of a tertiary care institute over a period of 18 months with 6 months of follow-up. This study enrolled 50 patients diagnosed with GBS. We analyzed medical records, clinical presentation, laboratory results, electrophysiological findings, and treatment modalities. RESULTS: This study enrolled

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Tertia, Clarissa, Ni Made Dwita Pratiwi, and I. Komang Arimbawa. "Correlation of Total Protein in Cerebrospinal Fluid with the Type of Guillain-Barre Syndrome based on the Electrodiagnostic Examination at Prof. Dr. IGNG Ngoerah General Hospital Denpasar." International Journal of Research and Review 10, no. 8 (2023): 1069–75. http://dx.doi.org/10.52403/ijrr.202308135.

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Introduction: Guillain-Barre syndrome (GBS) is an autoimmune disease of the peripheral nervous system with an incidence of around 0.6 to 2.4 cases per 100,000 population. GBS pathogenesis is related to inflammatory factors, cytokines, chemokines, and complement. Protein levels in the cerebrospinal fluid of GBS patients will increase due to damage or increased permeability of the blood-nerve barrier and blood-cerebrospinal fluid (CSF) barrier. However, there are still pros and cons to the relationship between the amount of CSF protein and the subtype of GBS. Objective: To determine the most com

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Sharma, Krishna Sagar, Rupa Singh, and Gauri Shankar Shah. "Guillain Barre Syndrome: Major Cause of Acute Flaccid Paralysis in Children and Adolescents of Nepal." Journal of Nepal Paediatric Society 31, no. 2 (2011): 93–97. http://dx.doi.org/10.3126/jnps.v31i2.4065.

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Introduction. Guillain Barre Syndrome (GBS) is a post infectious polyneuropathy involving mainly motor but sometimes sensory and autonomic nerves. It is an acquired disease of the peripheral nerves that is characterized by rapidly progressing paralysis, areflexia and albumino-cytological dissociation in CSF. Methodology: Prospective, descriptive, observational, hospital based study was carried out to find out the clinico-epidemiological features of GBS including existing treatment modalities and its outcome. All cases fulfilled the criteria for AFP (Acute flaccid Paralysis) surveillance was in

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Mahajan, Roopali, Jayantee Kalita, Vishal Jha, Nagendra B. Gutti, Prakash C. Pandey, and Usha K. Misra. "Temporal Pattern of Individual Neurological Function Recovery in Guillain–Barré Syndrome." Journal of Clinical Medicine 13, no. 18 (2024): 5635. http://dx.doi.org/10.3390/jcm13185635.

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Background: There is paucity of studies on the temporal pattern of recovery of facial, bulbar, sensory, motor, and autonomic dysfunction in Guillain–Barré syndrome (GBS), although many studies have reported short- and long-term functional outcomes. We report the temporal pattern of recovery of various neurological functions in GBS, and compare the pattern of recovery between acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and acute motor axonal neuropathy (AMAN). Methods: Forty-two patients with GBS were prospectively included, and their clinical details, including peak disabili

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Yamana, Masaki, Motoi Kuwahara, Yuta Fukumoto, Keisuke Yoshikawa, Kazuo Takada, and Susumu Kusunoki. "Guillain-Barré syndrome and related diseases after influenza virus infection." Neurology - Neuroimmunology Neuroinflammation 6, no. 4 (2019): e575. http://dx.doi.org/10.1212/nxi.0000000000000575.

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ObjectiveWe examined the clinical and serologic features of Guillain-Barré syndrome (GBS)-related diseases (GBSRDs), including GBS, Fisher syndrome (FS), and Bickerstaff brainstem encephalitis (BBE), after influenza virus infection (GBSRD-I) to reveal potential underlying autoimmune mechanisms.MethodsWe retrospectively investigated the presence of antiglycolipid antibodies against 11 glycolipids and the clinical features of 63 patients with GBSRD-I. Autoantibody profiles and clinical features were compared with those of 82 patients with GBSRDs after Campylobacter jejuni infection (GBSRD-C).Res

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Koike, Haruki, Yuki Fukami, Ryoji Nishi, et al. "Ultrastructural mechanisms of macrophage-induced demyelination in Guillain-Barré syndrome." Journal of Neurology, Neurosurgery & Psychiatry 91, no. 6 (2020): 650–59. http://dx.doi.org/10.1136/jnnp-2019-322479.

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ObjectiveTo describe the pathological features of Guillain-Barré syndrome focusing on macrophage-associated myelin lesions.MethodsLongitudinal sections of sural nerve biopsy specimens from 11 patients with acute inflammatory demyelinating polyneuropathy (AIDP) exhibiting macrophage-associated demyelinating lesions were examined using electron microscopy. A total of 1205 nodes of Ranvier were examined to determine the relationship of the macrophage-associated demyelinating lesions with the nodal regions. Additionally, immunohistochemical and immunofluorescent studies were performed to elucidate

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Ananta Basudev, Mishra. "Acute Inflammatory Demyelinating Polyneuropathy Following Japanese Encephalitis: A Rare Neurological Sequela." Global Journal of Infectious Diseases and Clinical Research 11, no. 1 (2025): 010–12. https://doi.org/10.17352/2455-5363.000064.

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Japanese Encephalitis (JE) is a neurotropic viral infection endemic to Asia, primarily transmitted by Culex mosquitoes. While Central Nervous System (CNS) involvement is well-documented, peripheral nervous system complications such as Acute Inflammatory Demyelinating Polyneuropathy (AIDP)—a variant of Guillain-Barré Syndrome (GBS)—remain exceedingly rare. We report the case of a 20-year-old male presenting with altered sensorium, seizures, and progressive limb weakness. Neuroimaging revealed meningoencephalitis with an acute infarct in the left parietal region. Japanese Encephalitis Virus (JEV

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Liu, Shuping, Zheman Xiao, Min Lou, et al. "Guillain-Barré syndrome in southern China: retrospective analysis of hospitalised patients from 14 provinces in the area south of the Huaihe River." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 6 (2018): 618–26. http://dx.doi.org/10.1136/jnnp-2017-316930.

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ObjectivesThe clinical and epidemiological profiles of Guillain-Barré syndrome (GBS) in southern China have yet to be fully recognised. We aimed to investigate the subtypes of GBS in southern China, compare the clinical features of demyelinating form with that of axonal form and test whether preceding infections and age have influence on the clinical phenotype, disease course and severity of GBS.MethodsMedical records of patients with a diagnosis of GBS admitted to 31 tertiary hospitals, located in 14 provinces in southern China, from 1 January 2013 to 30 September 2016, were collected and ret

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Papathanasiou, Athanasios, and Ioannis Markakis. "Clinical Heterogeneity of Guillain-Barré Syndrome in the Emergency Department: Impact on Clinical Outcome." Case Reports in Emergency Medicine 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/4981274.

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Guillain-Barré syndrome (GBS) is mainly classified into acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor axonal neuropathy (AMAN). Although diagnosis of GBS requires progressive weakness and universal areflexia or hyporeflexia, cases of GBS with preserved or increased deep tendon reflexes (DTRs) have been increasingly recognized. We report three cases of GBS, presenting at a single unit in six months. Our first case presented with pure sensory symptoms. The second case had nonspecific generalized weakness, while the third presented with typical ascending weakness. One of

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Yadlapati, Venkata Sai Suhas, Rithvik Ramesh, Lakshmi Narasimhan Ranganathan, Sundar Shanmugam, Philo Hazeena, and Deepa Avadhani. "Stiff tongue syndrome and multifocal immune neuropathy in a young man with anti-glutamic acid decarboxylase and unclassified antibodies." BMJ Case Reports 18, no. 6 (2025): e265124. https://doi.org/10.1136/bcr-2025-265124.

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Anti-glutamic acid decarboxylase 65 antibody (anti-GAD65Ab)-mediated neurological syndromes are constantly expanding with recent literature descriptions of peripheral nerve involvement. This report describes a man in his 30s presenting with progressive episodic tongue stiffness and upper limb weakness, with examination revealing restricted tongue movement and asymmetric proximal predominant upper limb weakness. Electrophysiology showed conduction blocks, and imaging revealed inflammatory brachial plexus changes. Anti-GAD65Ab and an unclassified neuronal antibody were identified on serological

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Zutshi, Kalpana. "Comparative Study between COVID Associated Guillan Barre Syndrome and Non-COVID Associated Guillan-Barré Syndrome." Journal of Advanced Research in Medical Science & Technology 08, no. 03 (2021): 10–12. http://dx.doi.org/10.24321/2394.6539.202110.

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More than 12 million people have been infected with COVID-19 worldwide, with more than 500,000 deaths to date.1 Although COVID-19 research is rapidly evolving, new findings must be thoroughly scrutinised before any conclusions or treatment protocols are established or amended.2 Although COVID-19 is most usually associated with respiratory symptoms such as cough and dyspnea; it has recently been associated with a neurotropic presentation.3 Guillain-Barré Syndrome (GBS) is best described as an acute inflammatory polyradiculoneuropathy clinically characterized by areflexia and progressive weaknes

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Islam, Md Rashedul, Tanbin Rahman, Rumana Habib, Aminur Rahman, Nirmalendu Bikash Bhowmik, and Md Amirul Haque. "Clinical Characteristics, Laboratory Findings and Functional Outcomes of Guillain-Barre Syndrome: Experience of 50 Cases in Bangladesh." Journal of National Institute of Neurosciences Bangladesh 9, no. 2 (2024): 108–15. http://dx.doi.org/10.3329/jninb.v9i2.65401.

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Background: Guillain-Barré Syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy which is one of the most frequent causes of acute flaccid paralysis. GBS has diverse clinical phenotype and functional outcome. Objective: The purpose of the present study was to evaluate clinical profiles and outcomes of GBS patients admitted in a tertiary care centre of Bangladesh. Methodology: This prospective cohort study was conducted in the Department of Neurology from January 2016 to June, 2020 in BIRDEM General Hospital, Dhaka, Bangladesh. Adult patients more than or equal to 18 years of age wh

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Chowdhury RA. "Guillain-Barre Syndrome in North-Eastern population of Bangladesh: Electrophysiologic Pattern from the largest local cohort." Journal of Sylhet Women’s Medical College 15, Number 1 (2025): 33–36. https://doi.org/10.47648/jswmc2025v15-01-116.

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Objective: To determine the pattern of electrophysiologic findings in Guillain-Barre Syndrome (GBS) patients in north-eastern Bangladeshi population. Methods: This observational study was carried out at neurophysiology laboratory in a specialized center of Sylhet with the diagnostic facility for nerve conduction study, from July 22- July 2024, Total patient was 248 . Data were collected from the patients who underwent NCS with a provisional diagnosis of GBS. Result: A total of 248 patients , mean age of 43 ± 13.24 years and a slightly male dominance (57.4%) were evaluated. Alost half of the pa

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Debnath, Bithi, Mohammad Enayet Hussain, Nazmul Haque, et al. "Clinical and ElectrophysiologicAspects of Guillain Barre Syndrome among Children: Experience at Referral Tertiary Care Hospital in Bangladesh." Journal of National Institute of Neurosciences Bangladesh 5, no. 1 (2019): 2–7. http://dx.doi.org/10.3329/jninb.v5i1.42160.

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Background: Guillain Barre Syndrome (GBS) is an acute polyradiculopathy which is quite common in all ages. Objective: The aim of this study was to evaluate the clinical and electrophysiologicaspects of Guillain Barre Syndrome (GBS) in children. Methodology: This cross-sectional study was carried out in the Department of Neurophysiology of National Institute of Neurosciences and Hospital, Bangladesh from July 2016 to June 2018. Patients under 18 years of age fulfilling Brighton diagnostic criteria for GBS were included in this study. These patients were evaluated by detailed history

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Sekar, Ezhumalai Arunraj, R. Ravichandran, and V. Ravikumar. "Electrophysiologic Diagnostic Patterns Analysis in Patients with Guillain Barre Syndrome in Tertiary Care Centre." International Journal of Pharmaceutical and Clinical Research 15, no. 3 (2023): 59–65. https://doi.org/10.5281/zenodo.12685071.

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<strong>Introduction:</strong> The Guillain-Barre syndrome (GBS) is an acute immune-mediated neuropathy and is recognized clinically by the presence of acute, rapidly progressive flaccid weakness, diminished or absent reflexes and albumin cytological dissociation in cerebrospinal fluid. Each subtype may have a different immunopathogenesis therefore, may have different approach treatments hence identification of these subtypes is important. The aims of the study were to identify the incidence of patients meeting electrophysiological criteria for demyelinating or axonal subtypes based on th

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Mian Ayaz ul Haq, Yusra Samin, Talha Durrani, Danish Nabi, Muhammad Owais Khan, and Muhammad Adeel Khan. "Clinical and demographic characteristics of guillain-barré syndrome (GBS) variants in a tertiary care hospital." Professional Medical Journal 30, no. 07 (2023): 851–55. http://dx.doi.org/10.29309/tpmj/2023.30.07.7494.

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Objective: To evaluate clinical and demographic characteristics of guillian-barre syndrome. Material & Methods: Study Design: Descriptive, Cross-sectional study. Setting: Department of Neurology, Lady Reading Hospital, Peshawar. Period: December 2020 to March 2022. Results: The study identified 117 patients with GBS, and the mean age was 43.59 ± 17.39 years. There were 78 male (67%) and 39 female (33%) patients. The most common GBS subtype was AMAN (46.2%), followed by AMSAN (34.2%), AIDP (16.2%), and atypical (2.6%). The study found a significant difference in gender distribution between

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Adhikari, Arpita D., Aditi P. Shinde, Sharandeep Kaur G. Siddhu, and Mona P. Gajre. "Study of clinical profile and outcome in children aged 1-12 years presenting with Guillain Barre syndrome." International Journal of Contemporary Pediatrics 10, no. 5 (2023): 685–90. http://dx.doi.org/10.18203/2349-3291.ijcp20231144.

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Background: Guillain-Barré syndrome (GBS) is a group of clinical syndromes involving acute polyneuropathy secondary to an immune-mediated process. The aim of the research is to study clinical profile and outcome in children aged 1-12 years presenting with GBS. Methods: It is a prospective plus retrospective observational study (5-year retrospective + 18 months prospective). All cases of GBS admitted from January 2020-july 2021 were enrolled for the study and retrospective cases were taken from case record from January 2015 onwards in a tertiary care centre. Results: Total 45 children were enr

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Wirtshafter, Stephanie, and Iqra Iqbal. "Acute Inflammatory Demyelinating Polyneuropathy (AIDP) Masked by Autoimmune Thyroiditis." Journal of the Endocrine Society 5, Supplement_1 (2021): A918. http://dx.doi.org/10.1210/jendso/bvab048.1875.

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Abstract Hashimoto’s thyroiditis and Guillain-Barre syndrome (GBS) are autoimmune disorders that are both well-known in their own right. Hashimoto’s is one of the most common causes of primary hypothyroidism, and GBS involves immune mediated damage to the peripheral nervous system. The association between the two is a rare clinical entity. This case demonstrates that these entities can occur together and could be related in similar pathophysiology. A 37 year old male presented with complaints of bilateral hand and feet numbness for one month. The numbness started in the hands, then involved th

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