Готові списки джерел за темами / Transungual Drug Delivery

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Добірка наукової літератури з теми "Transungual Drug Delivery"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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Статті в журналах з теми "Transungual Drug Delivery"

Shikha, Rashmi, Dheeraj Bisht, Manoj Bhardwaj, and Manoj Bisht. "Formulation and Evaluation of Terbinafine HCL loaded Nanoparticles for Transungual delivery of drug in Fungal infection." Journal of Neonatal Surgery 14, no. 28S (2025): 383–402. https://doi.org/10.63682/jns.v14i28s.6615.

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In this review we mainly concern about the transungual delivery of drug to treat nail infection which is caused by the infection of a fungus. Transungual drug delivery is regarded as a very desirable treatment for various diseases in nail treatment due to its localized effects, which promote adherence while causing less unfavorable systemic effects. The nail is one of the toughest portions of the human body, and the nail plate presents a challenging barrier for drugs moiety to pass through . Topical medication delivery treatment is useful for treating numerous nail problems since it has locali

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Jeremiah, M. Christi* Chintan Aundhia Avinash Seth Nirmal Shah Dip Kondhia Snehal Patel. "REVIEW ON TRANSUNGUAL DRUG DELIVERY SYSTEM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 09 (2017): 686–706. https://doi.org/10.5281/zenodo.1036583.

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Topical therapy is highly desirable in treating nail disorders due to its localized effects, which results in minimal adverse systemic events and possibly improved adherence. The absorption of drugs into the nail unit, to the nail plate, is highly desirable to treat nail disorders; however, the effectiveness of topical therapies is limited by minimal drug permeability through the nail plate. Nail permeability is however quite low and limits topical therapy to early/mild disease states such as onychomycosis (fungal infections of the nail). Current research on nail permeation that focuses on alt

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Shivakumar, H. N., Abhishek Juluri, B. G. Desai, and S. Narasimha Murthy. "Ungual and Transungual drug delivery." Drug Development and Industrial Pharmacy 38, no. 8 (2011): 901–11. http://dx.doi.org/10.3109/03639045.2011.637931.

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Shivakumar, H. N., M. A. Repka, and S. Narasimha Murthy. "Transungual drug delivery: an update." Journal of Drug Delivery Science and Technology 24, no. 3 (2014): 301–10. http://dx.doi.org/10.1016/s1773-2247(14)50049-4.

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Elkeeb, Rania, Ali AliKhan, Laila Elkeeb, Xiaoying Hui, and Howard I. Maibach. "Transungual drug delivery: Current status." International Journal of Pharmaceutics 384, no. 1-2 (2010): 1–8. http://dx.doi.org/10.1016/j.ijpharm.2009.10.002.

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Gaddime, Sonali B. Nagoba Shivappa N.* Suryawanshi S. R. Vijayendra Swamy S. M. "REVIEW ON TRANSUNGUAL: A NOVEL DRUG DELIVERY SYSTEM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 06, no. 01 (2019): 918–25. https://doi.org/10.5281/zenodo.2538345.

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Анотація:

The nail disorders are mainly due to fungal infection. When the drug is given through oral or systemic route, the potency of drugs gets decreased at the site of action. To avoid this loss of drug potency topical route of administration is used. This review is mainly about transungual drug delivery which means transfer of drug across the keratinized nails to treat nail fungal diseases and increasing bioavailability of various drugs used for nail diseases. Nail diseases are mainly caused by fungal infections; fungi are most responsible for nail diseases. So treatment of such infections is no

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Nair, Anroop B., Bandar E. Al-Dhubiab, Jigar Shah, et al. "Constant Voltage Iontophoresis Technique to Deliver Terbinafine via Transungual Delivery System: Formulation Optimization Using Box–Behnken Design and In Vitro Evaluation." Pharmaceutics 13, no. 10 (2021): 1692. http://dx.doi.org/10.3390/pharmaceutics13101692.

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Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs through the thick multi-layered keratinized nail plate. The objective of this investigation was to develop a gel formulation, and to optimize and evaluate the transungual delivery of terbinafine using the constant voltage iontophoresis technique. Statistical analysis was performed using Box–Behnken design to optimize the transungual delivery of terbinafine by examining crucial variables namely concentration of polyethylene glycol, voltage, and duration of application (2–6 h). Optimization data in ba

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Nair, Anroop B., Bandar Aldhubiab, Jigar Shah, et al. "Design, Development, and Evaluation of Constant Voltage Iontophoresis for the Transungual Delivery of Efinaconazole." Pharmaceutics 15, no. 5 (2023): 1422. http://dx.doi.org/10.3390/pharmaceutics15051422.

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The efficacy of topical antifungal therapy in onychomycosis has been hindered by the failure of the antimycotic to permeate the nail plate. This research aims to design and develop a transungual system for the effective delivery of efinaconazole utilizing constant voltage iontophoresis. Seven prototype drug-loaded hydrogel formulations (E1–E7) were prepared to assess the influence of solvent (ethanol) and cosolvent (Labrasol®) on transungual delivery. Optimization was performed to evaluate the effect of three independent variables; voltage, solvent-to-cosolvent ratio, and penetration enhancer

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Bharti, Lohani *and Ganesh Kumar. "MEDICATED NAIL LACQUERS – FOR EFFECTIVE TREATMENT OF NAIL DISORDERS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1392–403. https://doi.org/10.5281/zenodo.1197498.

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Анотація:

Transungual drug delivery system is related with the drug delivery over the nail, which is hard because of presence of keratin network into the nail. So in this review mainly concentrated on drug delivery over nail by using nail lacquer formulations, which containing drug on it .The drug delivery via nail plate is done due to association of several diseases into nail, for e.g. onychomycosis, psoriasis, paronychia, onycholysis .These nail diseases are occurred due to presence of several microorganisms like- several fungi, bacteria, parasites and to cure these diseases of nail, several medicatio

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Chouhan, Pradeep, та T. R. Saini. "Hydroxypropyl-β-cyclodextrin: A Novel Transungual Permeation Enhancer for Development of Topical Drug Delivery System for Onychomycosis". Journal of Drug Delivery 2014 (6 серпня 2014): 1–7. http://dx.doi.org/10.1155/2014/950358.

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Анотація:

The treatment of onychomycosis is a challenging task because of unique barrier properties of the nail plate which hampers the passage of antifungal drugs in a concentration required to eradicate the deeply seated causative fungi in the nail bed. In present investigation, application of hydroxypropyl-β-cyclodextrin (HP-β-CD) was established as an effective and nail friendly transungual drug permeation enhancer especially for poorly water soluble drugs using terbinafine hydrochloride as a poorly soluble drug. HP-β-CD significantly improves hydration of nail plates and increases solubility of ter

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Більше джерел

Дисертації з теми "Transungual Drug Delivery"

Vanstone, Simon. "Optical drilling of the human nail plate to facilitate transungual drug delivery." Thesis, University of Bath, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.723341.

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Анотація:

The nail plate is a thick, tightly bound structure that protects the underlying nail bed from water loss, physical abrasion and infections. Despite its barrier properties, organisms are capable of traversing across and around the plate causing infection to the nail unit. Nail disease represents a time and cost intensive problem for the healthcare industry, with current topical and systemic treatment methods failing to stop the rise in incidence. Physical poration of the nail plate is discussed here with the first use of a femtosecond pulsed, fibre optic delivered, visible-light laser for drill

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Palliyil, Biji. "The Preformulation and Formulation Development for Transungual Delivery of Antifungal Drug Ciclopirox olamine." Diss., Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/224325.

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Pharmaceutical Sciences Ph.D. Onychomycosis also known as dermatophytic onychomycosis is the fungal infection of the toenails and fingernails, characterized by discoloration and thickening of the nail and involves the nail plate, nail bed and nail folds. The disease is more than a cosmetic problem, as it severely impacts the patient's quality of life. Onychomycosis is an opportunistic infection in special subpopulations of patients suffering from diabetes, psoriasis, HIV/AIDS etc. The current treatment strategies involve systemic delivery of oral antifungal agents including azoles (e.g.

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Li, Cong. "A PREFORMULATION DEVELOPMENT STUDY FOR THE TRANSUNGUAL DELIVERY OF THE ANTIFUNGAL DRUG ECONAZOLE NITRATE." Master's thesis, Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/241428.

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Pharmaceutical Sciences M.S. Onychomycosis is the most common disease of nails and constitutes about a half of all nail abnormalities. The thickness of the nails become the major challenge in developing a topical formulation for treatment on OM. In this study, penetration enhancers are used to enhance the solubility and permeability of the drug enconazole nitrate into the nail and the skin. It turns out of all the penetration enhancers, thiourea is the best choice because it can improve the solubility and nail penetration of econazole nitrate at the same time. Temple University--These

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Li, Cong. "The preformulation and formulation development for the transungual delivery of the antifungal drug econazole nitrate." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/340105.

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Анотація:

Pharmaceutical Sciences Ph.D. Onychomycosis is fungal infection of toe nails or fingernails caused by a fungal microbe that invades the nail bed. It is the most common disease of the nails and constitutes about a half of all nail abnormalities and may affect toenails or fingernails, but toenail infections are particularly common. It occurs in about 10 percent of the adult population. The most common symptoms of fungal nail infection are thickening and discoloration of the nail. Treatment of onychomycosis is challenging because the infection is embedded in the nail making it difficult for

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Книги з теми "Transungual Drug Delivery"

Transungual Drug Delivery. CRC Press, 2012.

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Частини книг з теми "Transungual Drug Delivery"

"Transdermal and transungual drug delivery systems." In Drug Delivery. Elsevier, 2025. https://doi.org/10.1016/b978-0-443-26787-1.00008-4.

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Aundhia, Chintan, Tamanna Bhanderi, Ghanshyam Parmar, Niyati Shah, Mamta Kumari, and Nirmal Shah. "Transungual Drug Delivery System for Treatment of Onychomycosis." In Multidisciplinary Approaches in Pharmaceutical Sciences. B P International (a part of SCIENCEDOMAIN International), 2023. http://dx.doi.org/10.9734/bpi/mono/978-81-19315-51-2/ch20.

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