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Статті в журналах з теми "Tuberculosis (TB) Management"

Автор: Grafiati

Опубліковано: 7 червня 2025

Оновлено: 2 серпня 2025

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1

Panchatsharam, Adithyan, and Revathy Sundaramurthy. "Cutaneous tuberculosis-management." International Journal of Research in Dermatology 9, no. 6 (2023): 394–402. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20233186.

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Анотація:

Since antiquity, people have been plagued by tuberculosis (TB), and its effects are likely older than recorded history. For many centuries, TB was the most significant human infection due to its devastating mortality and morbidity rates and global prevalence. In developed nations, there is less evidence of Mycobacterium tuberculosis infections as a result of improved socioeconomic status. In developing nations like India, it is still regarded as a significant cause of morbidity and mortality. Cutaneous TB occurs worldwide and it comprises only a small proportion of all cases of TB, but conside

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2

Jabbar, Naila, Muhammad Arif Ali, and Umair Sohail. "TUBERCULOSIS MANAGEMENT." Professional Medical Journal 22, no. 09 (2015): 1144–49. http://dx.doi.org/10.29309/tpmj/2015.22.09.1058.

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Background: Medical practitioners are the main source of health care forpatients in Pakistan due to their availability at all times. Limited information is available related tothe management of Tuberculosis (TB) among the practitioners. Study Design: Cross sectionalstudy. Setting: Through stratified random sampling among the practitioners of Lahore, Punjab.Period: May 2014 to August 2014. Methods: They were presented with a questionnaire andtheir answers examined according to the international designed strategy for TB management.Results: TB management has a positive relationship with experienc

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3

Caminero, Jose, and Charles Daley. "Management of Multidrug-Resistant Tuberculosis." Seminars in Respiratory and Critical Care Medicine 39, no. 03 (2018): 310–24. http://dx.doi.org/10.1055/s-0038-1661383.

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AbstractDrug-resistant strains of Mycobacterium tuberculosis pose a major threat to global tuberculosis control. Despite the availability of curative antituberculosis therapy for nearly half a century, inappropriate and inadequate treatment of tuberculosis, as well as unchecked transmission of M. tuberculosis, has resulted in alarming levels of drug-resistant tuberculosis. The World Health Organization (WHO) estimates that there were 600,000 cases of multidrug-resistant tuberculosis (MDR-TB)/rifampin-resistant (RR) tuberculosis in 2016, defined as strains that are resistant to at least isoniaz

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4

Yandhi, Rama, and Zen Ahmad. "Management of Isoniazid Monoresistant Tuberculosis." Bioscientia Medicina : Journal of Biomedicine and Translational Research 8, no. 7 (2024): 4606–12. http://dx.doi.org/10.37275/bsm.v8i7.1029.

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lsoniazid (INH) is one of the main first-line drugs used for the treatment of active tuberculosis (TB) and latent TB infection because it has bactericidal capabilities and a good level of safety. The presence of TB germs that are resistant to INH will reduce the effectiveness of TB treatment. The treatment mix for INH monoresistant TB patients is a combination of rifampicin (R), isoniazid (H), pyrazinamide (Z), ethambutol (E), and levofloxacin (Lfx) or R-H-Z-E-Lfx given for 6 months. If a health facility provides loose TB medication, the patient can be given a combination of treatment without

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5

Sujit, Kumar Mohanty, Choudhuri Sanjay, and Panda Sridhar. "Study of Gastrointestinal Tuberculosis and Role of Surgery in Its Management." International Journal of Pharmaceutical and Clinical Research 16, no. 2 (2024): 648–52. https://doi.org/10.5281/zenodo.11073020.

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<strong>Background:</strong> While abdominal TB is less frequent than its pulmonary cousin, this research will look at the clinical signs of Gastrointestinal Tuberculosis, the consequences of surgical therapies, and the anatomical distribution throughout the digestive system. <strong>Materials and Methods:</strong> Prospective observational research was carried out at SCB Medical college and Hospital, Cuttack from August 2020 to October 2022. The trial group consisted of fifty individuals with confirmed gastrointestinal TB. The diagnosis was made based on the clinical history, s

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6

Lai, Qingfeng. "Risk Factors and Management of Adolescent Tuberculosis." Highlights in Science, Engineering and Technology 123 (December 24, 2024): 77–83. https://doi.org/10.54097/dvw38e03.

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Tuberculosis (TB) is an acute or chronic pulmonary infectious disease caused by Mycobacterium tuberculosis and transmitted through the air, which is one of the major infectious diseases threatening human life and health. It is a communicable disease primarily spread via respiratory droplets. TB can affect individuals of any age, this study refers to TB occurring in individuals aged 10-19 (inclusive) as adolescent TB. Despite the overall good control of tuberculosis in China, the incidence rate among adolescents has been rising. Adolescent TB is influenced by both genetic and environmental fact

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7

Blumberg, Lucille, Gboyega A. Ogunbanjo, and David N. Durrheim. "Turberculosis: Current issues on diagnosis and management." South African Family Practice 45, no. 2 (2003): 5. http://dx.doi.org/10.4102/safp.v45i2.1985.

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Анотація:

In 1993, the World Health Organisation (WHO) declared tuberculosis (TB) a global emergency and in 1996, South Africa declared TB as a priority disease. The most effective means of controlling TB is through rapid diagnosis by direct sputum microscopy for acid fast bacilli (AFB), or culture for Mycobacteium tuberculosis (MTB) and prompt initiation of the correct therapy by means of the Directly Observed Treatment, Short course (DOTS) strategy. ln 1997, it was estimated that 10 million of the 30 million people infected with the human immuno-deficiency virus (HM worldwide were co-infected with TB.

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8

Shrivas, Arti, and Sarman Singh. "Tuberculosis Diagnosis and Management: Recent Advances." Journal of Global Infectious Diseases 17, no. 1 (2025): 3–9. https://doi.org/10.4103/jgid.jgid_112_24.

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Abstract Accurate and rapid diagnosis is crucial for starting effective treatment for tuberculosis (TB) and mitigating the transmission. Globally, nearly one-third of all TB cases remain undetected each year and consequently these are not reported. On top of that, the emergence of drug-resistant TB poses an added challenge. In the past 15 years, several advances have been made for improved diagnosis, including liquid culture and drug susceptibility, line probe assay for drug resistance detection, and cartridge-based nucleic acid amplification tests for rapid diagnosis of TB and drug resistance

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9

Dunn, R. N., and M. Ben Husien. "Spinal tuberculosis." Bone & Joint Journal 100-B, no. 4 (2018): 425–31. http://dx.doi.org/10.1302/0301-620x.100b4.bjj-2017-1040.r1.

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Анотація:

Tuberculosis (TB) remains endemic in many parts of the developing world and is increasingly seen in the developed world due to migration. A total of 1.3 million people die annually from the disease. Spinal TB is the most common musculoskeletal manifestation, affecting about 1 to 2% of all cases of TB. The coexistence of HIV, which is endemic in some regions, adds to the burden and the complexity of management. This review discusses the epidemiology, clinical presentation, diagnosis, impact of HIV and both the medical and surgical options in the management of spinal TB. Cite this article: Bone

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10

Padussis, James, Brett Loffredo, and David Mcaneny. "Minimally Invasive Management of Obstructive Gastroduodenal Tuberculosis." American Surgeon 71, no. 8 (2005): 698–700. http://dx.doi.org/10.1177/000313480507100816.

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Pulmonary tuberculosis (TB) is prevalent in Western urban centers, especially among immuno-compromised patients and immigrants. However, TB enteritis is a rare sequela, occurring in less than 1 per cent of this population. Tuberculosis may affect any portion of the gastrointestinal (GI) tract, and 85 per cent of cases manifest in the ileocecal region. However, the stomach and duodenum are involved in just 0.3–2.3% of TB cases that affect the gut. Gastric outlet obstruction due to TB has been traditionally treated by a surgical bypass operation, followed by anti-TB chemotherapy. In a recent rev

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11

Shetty, Ajoy Prasad, Vibhu Krishnan Viswanathan, and S. Rajasekaran. "Cervical spine TB – Current concepts in management." Journal of Orthopaedic Surgery 29, no. 1_suppl (2021): 230949902110069. http://dx.doi.org/10.1177/23094990211006936.

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Objective: Cervical tubercular disease (CTB) is a rare pathology and constitutes 3–5% of all spinal TB. It includes atlantoaxial TB and sub-axial TB. As the literature evidence on this subject is scarce, majority of issues concerning CTB are still controversial. The current narrative review comprehensively discusses the various aspects related to CTB. Literature search: An elaborate search was made using keywords cervical tuberculosis, atlantoaxial tuberculosis, sub-axial tuberculosis, and cervico-thoracic tuberculosis, on pubmed and google ( scholar.google.com ) databases on 2 December 2020.

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12

Khan, Munira, and Kogieleum Naidoo. "Unusual presentation of extrapulmonary tuberculosis: A case report on mammary tuberculosis." Southern African Journal of HIV Medicine 12, no. 2 (2011): 45–46. http://dx.doi.org/10.4102/sajhivmed.v12i2.197.

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This case study highlights an unusual manifestation of extrapulmonary tuberculosis (TB) in a person living with HIV, namely mammary TB. Clinicians practising in settings where HIV and TB are endemic need to be aware of the clinical presentation, diagnosis and management of mammary TB.

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13

Son, Eunjeong, and Doosoo Jeon. "Current situation of tuberculosis and National Strategic Plan for Tuberculosis Control in Korea." Journal of the Korean Medical Association 64, no. 4 (2021): 316–23. http://dx.doi.org/10.5124/jkma.2021.64.4.316.

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Tuberculosis (TB) remains a serious public health problem in Korea. Korea has the highest incidence rate (59 per 100,000 population) and the second-highest TB mortality rate (four per 100,000 population) among Organisation for Economic Cooperation and Development member countries. However, some progress has been made in TB control over the past decade. The notification rate of new TB cases has been gradually decreasing since reaching its highest rate in 2011 (78.9 per 100,000 population). In 2019, the notification rate of new TB cases was 46.4 per 100,000 population, with a reduction of 9.9% f

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14

Chong, Xue-Mei, Lucy McClean, and Paddy McMaster. "Tuberculosis: Implications for Dentistry." Dental Update 51, no. 4 (2024): 258–62. http://dx.doi.org/10.12968/denu.2024.51.4.258.

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Tuberculosis (TB) is an airborne infection caused by Mycobacterium tuberculosis complex and is highly infectious. Therefore, precautionary measures should be implemented prior to dental treatment to reduce the risk of infection to staff and other patients. Dental history and examination have a role in identification of TB infection. Complex medical history poses a challenge to safe patient management in a dental setting, and close liaison between different disciplines in managing these patients is of paramount importance. This article explores the classical clinical features of pulmonary TB, i

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15

Shah, Ira, and Zahabiya Aziz Nalwalla. "Newer perspectives - Diagnosis and management of pediatric tuberculosis." Wadia Journal of Women and Child Health 2 (October 10, 2023): 73–78. http://dx.doi.org/10.25259/wjwch_37_2023.

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Анотація:

Pediatric tuberculosis is a proxy indicator for the tuberculosis (TB) burden in the community. Although there has been a decline in the incidence, it is inadequate to meet the global goals for complete eradication of the disease. Childhood TB remains a challenge for clinicians and program managers. Advances in the diagnosis and treatment of pediatric tuberculosis are discussed in this review.

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16

Marais, Suzaan, Ronald Van Toorn, Felicia C. Chow, et al. "Management of intracranial tuberculous mass lesions: how long should we treat for?" Wellcome Open Research 4 (October 15, 2019): 158. http://dx.doi.org/10.12688/wellcomeopenres.15501.1.

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Tuberculous intracranial mass lesions are common in settings with high tuberculosis (TB) incidence and HIV prevalence. The diagnosis of such lesions, which include tuberculoma and tuberculous abscesses, is often presumptive and based on radiological features, supportive evidence of TB elsewhere and response to TB treatment. However, the treatment response is unpredictable, with lesions frequently enlarging paradoxically or persisting for many years despite appropriate TB treatment and corticosteroid therapy. Most international guidelines recommend a 9-12 month course of TB treatment for centra

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17

Marais, Suzaan, Ronald Van Toorn, Felicia C. Chow, et al. "Management of intracranial tuberculous mass lesions: how long should we treat for?" Wellcome Open Research 4 (October 31, 2019): 158. http://dx.doi.org/10.12688/wellcomeopenres.15501.2.

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Анотація:

Tuberculous intracranial mass lesions are common in settings with high tuberculosis (TB) incidence and HIV prevalence. The diagnosis of such lesions, which include tuberculoma and tuberculous abscesses, is often presumptive and based on radiological features, supportive evidence of TB elsewhere and response to TB treatment. However, the treatment response is unpredictable, with lesions frequently enlarging paradoxically or persisting for many years despite appropriate TB treatment and corticosteroid therapy. Most international guidelines recommend a 9-12 month course of TB treatment for centra

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18

Marais, Suzaan, Ronald Van Toorn, Felicia C. Chow, et al. "Management of intracranial tuberculous mass lesions: how long should we treat for?" Wellcome Open Research 4 (February 26, 2020): 158. http://dx.doi.org/10.12688/wellcomeopenres.15501.3.

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Анотація:

Tuberculous intracranial mass lesions are common in settings with high tuberculosis (TB) incidence and HIV prevalence. The diagnosis of such lesions, which include tuberculoma and tuberculous abscesses, is often presumptive and based on radiological features, supportive evidence of TB elsewhere and response to TB treatment. However, the treatment response is unpredictable, with lesions frequently enlarging paradoxically or persisting for many years despite appropriate TB treatment and corticosteroid therapy. Most international guidelines recommend a 9-12 month course of TB treatment for centra

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19

Lumentut, Anastasia Mariane, Hermie Tendean, Rizki Najoan, et al. "Tuberculosis in Pregnancy." Journal La Medihealtico 6, no. 2 (2025): 251–66. https://doi.org/10.37899/journallamedihealtico.v6i2.1870.

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Tuberculosis (TB) during pregnancy presents significant risks to both the mother and fetus, including complications such as abortion, preterm birth, low birth weight, and postpartum hemorrhage. The immune changes in pregnancy, particularly the shift in TH1/TH2 balance, increase the risk of latent TB reactivation. Diagnosing TB in pregnant women is challenging due to overlapping symptoms with normal pregnancy changes. However, early diagnosis is crucial for effective management, with molecular tests offering assistance, although bacterial culture remains the gold standard. High-risk pregnant wo

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20

Bandale, Dr Mukund Baburao, and Dr Sandipkumar Ramjivan Baheti. "Ashwagandha: Potential Integrative Management of Tuberculosis." International Journal of Innovative Research in Medical Science 5, no. 07 (2020): 257–60. http://dx.doi.org/10.23958/ijirms/vol05-i07/895.

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The World Health Organization TB (Tuberculosis) statistics for India for 2018 give an estimated incidence of 2.69 million cases.TB is being a challenge for India and worldwide developing countries pre and post antitubercular drug era. The major limitations clinicians face in management of TB is its MDR, immunosuppression, bad prognosis during course of treatment and associated side effects of anti- tubercular drugs putting patient in danger for multiple organ failure. The presence of comorbidities, nutritional deficiencies add up toll in the whole clinical presentation of tuberculosis manageme

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21

Bothamley, Graham. "The Tuberculosis Network European Trials Group (TBNET): new directions in the management of tuberculosis." Breathe 13, no. 3 (2017): e65-e71. http://dx.doi.org/10.1183/20734735.005517.

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The Tuberculosis Network European Trials Group (TBNET) is the largest clinical research organisation in Europe. Educational activities include the TBNET Academy and the European Advanced Course in Clinical Tuberculosis. Four of their publications are reviewed to show how the clinical management of tuberculosis is changing.Key pointsMost tuberculosis (TB) in contacts is found at their first visit.In contacts of pulmonary TB patients, the likelihood of later TB is ≤3%.Genetic tests can indicate when another antimycobacterial drug in the same class might be effective (e.g.rifabutin when there is

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22

BĂLTEANU, Mara, Mihaela TĂNĂSESCU, Gina CIOLAN, and Constantin MARICA. "The management of latent tuberculosis infection in Romania – limits and perspectives." Romanian Journal of Medical Practice 10, no. 3 (2015): 226–33. http://dx.doi.org/10.37897/rjmp.2015.3.2.

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Анотація:

In 2014 the World Health Organization adopted a new strategy for tuberculosis control – infectious disease with the highest mortality in the world after AIDS. This new strategy – The End TB Strategy – is aimed to reducing tuberculosis disease by 90% and tuberculosis mortality by 95%, so that by 2035 TB is no longer considered a problem global public health. The World Health Organization report on tuberculosis published in 2014 is estimated that about one third of the world population is infected with M. tuberculosis (approx. 2 billion); 5-10% of them will develop active disease, thus fullfilin

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23

Jain, Sonal, and Arun Kumar. "Clinical management of drug resistant tuberculosis: A comprehensive review." Asian Journal of Medical Sciences 5, no. 3 (2014): 1–9. http://dx.doi.org/10.3126/ajms.v5i3.9698.

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Анотація:

Despite the introduction 40 years ago of the inexpensive and effective four-drug (isoniazid, rifampicin, pyrazinamide and ethambutol) treatment regimen, tuberculosis (TB) continues to cause considerable morbidity and mortality worldwide. This is because of development of drug resistance in tuberculosis strains, usually called as MDR/XDR-TB. Consequently, novel drugs and regimens for management of these drug resistant TB forms are emerging. Such regimens probably utilize both repurposed drugs and new chemical drugs. This article covers current concepts and recent advances in TB drug discovery a

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24

Sonal Jain and Arun Kumar. "Clinical management of drug resistant tuberculosis: A comprehensive review." Asian Journal of Medical Sciences 5, no. 3 (2014): 1–9. https://doi.org/10.71152/ajms.v5i3.3331.

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Анотація:

Despite the introduction 40 years ago of the inexpensive and effective four-drug (isoniazid, rifampicin, pyrazinamide and ethambutol) treatment regimen, tuberculosis (TB) continues to cause considerable morbidity and mortality worldwide. This is because of development of drug resistance in tuberculosis strains, usually called as MDR/XDR-TB. Consequently, novel drugs and regimens for management of these drug resistant TB forms are emerging. Such regimens probably utilize both repurposed drugs and new chemical drugs. This article covers current concepts and recent advances in TB drug discovery a

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25

Tantular, Rezki. "Tuberculosis Management in Renal Transplant Recipient." Malang Respiratory Journal 1, no. 1 (2019): 17–25. http://dx.doi.org/10.21776/ub.mrj.2019.001.01.4.

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Background: Tuberculosis (TB) is a major global health problem and South-East Asia was the leading contributor of TB cases globally. Treatment regimen of TB for an individual patient depends on multiple factors, and one of them was patient’s comorbidities. Comorbidities such as renal failure or concurrent use of immunosuppressant drugs post renal transplantation will influence pharmacological aspect of anti-tuberculosis drugs. Case: A 38-year-old male with a history of chronic renal failure who had undergone routine hemodialysis was diagnosed with pulmonary tuberculosis and was scheduled for a

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26

Bayusentono, Sulis, Erwin Ramawan, and Henry Dominica. "NEGLECTED COXITIS TUBERCULOSA MANAGEMENT IN CHILDREN." (JOINTS) Journal Orthopaedi and Traumatology Surabaya 8, no. 1 (2019): 35. http://dx.doi.org/10.20473/joints.v8i1.2019.35-46.

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Background: Tuberculosis is one of serious health problems throughout the world, including in Indonesia. The incidence of tuberculosis continue to increase annually, especially the case of bone tuberculosis which is part of tuberculosis extra pulmonary as much as 10-20%.Case: A case report of 2 years old girl, with a neglected posterior hip dextra et causa coxitis tuberculosa dextra in Dr. Soetomo General Hospital, in period October 2013 until September 2015. Data were taken from the retrospective medical record through the anamnesis, physical findings, radiological, and laboratory examination

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27

Pandey, Nalini Bala. "Pregnancy with Tuberculosis: What’s New!" Journal of Advanced Research in Medicine 8, no. 4 (2021): 26–31. http://dx.doi.org/10.24321/2349.7181.202120.

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Анотація:

Pregnancy with Tuberculosis (TB) can adversely affect the health of the gravida, foetus, and neonate with a spectrum of short and long-term implications. Prevention, diagnosis, and management with a multi-disciplinary team (MDT) approach of TB in pregnancy can improve maternal and perinatal outcomes. Tuberculosis preventive therapy (TPT) can prevent active disease progression and improve the outcome. More recently, active steps to enhance the collaborative activities between maternal health programmes and the National Tuberculosis Elimination Programme (NTEP) have been proposed to ensure early

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28

Dara, Yash, Doron Volcani, Kush Shah, Kevin Shin, and Vishwanath Venketaraman. "Potentials of Host-Directed Therapies in Tuberculosis Management." Journal of Clinical Medicine 8, no. 8 (2019): 1166. http://dx.doi.org/10.3390/jcm8081166.

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Анотація:

Tuberculosis (TB) remains as a leading cause of mortality in developing countries, persisting as a major threat to the global public health. Current treatment involving a long antibiotic regimen brings concern to the topic of patient compliance, contributing to the emergence of drug resistant TB. The current review will provide an updated outlook on novel anti-TB therapies that can be given as adjunctive agents to current anti-TB treatments, with a particular focus on modulating the host immune response to effectively target all forms of TB. Additional potential therapeutic pathway targets, in

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29

Getahun, Haileyesus, Alberto Matteelli, Ibrahim Abubakar, et al. "Management of latent Mycobacterium tuberculosis infection: WHO guidelines for low tuberculosis burden countries." European Respiratory Journal 46, no. 6 (2015): 1563–76. http://dx.doi.org/10.1183/13993003.01245-2015.

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Latent tuberculosis infection (LTBI) is characterised by the presence of immune responses to previously acquired Mycobacterium tuberculosis infection without clinical evidence of active tuberculosis (TB). Here we report evidence-based guidelines from the World Health Organization for a public health approach to the management of LTBI in high risk individuals in countries with high or middle upper income and TB incidence of <100 per 100 000 per year. The guidelines strongly recommend systematic testing and treatment of LTBI in people living with HIV, adult and child contacts of pulmonary TB

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30

Dzinamarira, Tafadzwa, Mohd Imran, and Claude Mambo Muvunyi. "The Management of Infectious Diseases in Comorbidity with Tuberculosis." Medicina 58, no. 10 (2022): 1406. http://dx.doi.org/10.3390/medicina58101406.

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31

Dhawan, Manish, Steffy Angural, and Manisha Parmar. "TUBERCULOSIS DURING THE COVID-19: IMPACT, CHALLENGES AND MANAGEMENT." Journal of Experimental Biology and Agricultural Sciences 8, Spl-1-SARS-CoV-2 (2020): S79—S86. http://dx.doi.org/10.18006/2020.8(spl-1-sars-cov-2).s79.s86.

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Анотація:

The corona virus disease 2019 (COVID-19) has caused substantial disruptions to health services due to overburdening the health system. Hence, there are severe obstructions in tuberculosis (TB) services in India's primary health care and hospital settings. Several restrictions, such as lockdown, self-isolations, and other public health guidelines to prevent viral transmission, impacted the delivery of essential facilities for TB management. A significant reduction in tuberculosis testing in the public health sector has been noticed, which is an alarming situation in India. However, there are se

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32

Meca, Andreea-Daniela, Liliana Mititelu-Tarțău, Maria Bogdan, Lorena Anda Dijmarescu, Ana-Maria Pelin, and Liliana Georgeta Foia. "Mycobacterium tuberculosis and Pulmonary Rehabilitation: From Novel Pharmacotherapeutic Approaches to Management of Post-Tuberculosis Sequelae." Journal of Personalized Medicine 12, no. 4 (2022): 569. http://dx.doi.org/10.3390/jpm12040569.

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Анотація:

Tuberculosis (TB) is still a worldwide public health burden, as more than 1.3 million deaths are expected to be reported in 2021. Even though almost 20 million patients have completed specific anti-TB treatment and survived in 2020, little information is known regarding their pulmonary sequelae, quality of life, and their need to follow rehabilitation services as researchers shifted towards proper diagnosis and treatment rather than analyzing post-disease development. Understanding the underlying immunologic and pathogenic mechanisms during mycobacterial infection, which have been incompletely

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33

Tellez Bolaños, Vianey Guadalupe, Alejandra Lizbeth Salinas Atriano, Karla Daniela Salgado Guizar, Louis Fernando Robles Fernandez, Francisco Javier Pedraza Murillo, and Roberto Camarena Álvarez. "Cerebral tuberculomas: manifestation of extrapulmonary tuberculosis in an immunocompromised patient. A case report." Iberoamerican Journal of Medicine 5, no. 4 (2023): 181–85. http://dx.doi.org/10.53986/ibjm.2023.0030.

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Tuberculosis (Tb) is, currently, the deadliest infectious disease and is caused by organisms of the Mycobacterium tuberculosis complex; the most common clinical manifestation is pulmonary involvement; however, it can also manifest as extrapulmonary affection in immunocompromised patients, especially in patients with human immunodeficiency virus (HIV) chronic infection up to 20% of the cases, despite being on adequate antiretroviral therapy. Within the extrapulmonary manifestations, affection of the central nervous system by hematogenous dissemination occurs in up to 5%, however, the finding of

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Waring, Justin, and National Tuberculosis Advisory Committee. "National Tuberculosis Advisory Committee Guideline: Management of Tuberculosis Risk in Healthcare Workers in Australia." Communicable Diseases Intelligence 41 (September 1, 2017): 119–203. https://doi.org/10.33321/cdi.2017.41.28.

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Tuberculosis (TB) is uncommon in Australia and not commonly managed by most healthcare workers (HCWs). However, even in a low incidence setting, occasional exposure of HCWs is inevitable and transmission of TB to HCWs leading to disease does occur. In addition, HCWs may have been recruited to Australia from countries with high TB incidence. These HCWs are more likely to be infected with TB before arrival and subsequently develop active disease while working in health settings in Australia. In 2001, there were 20 TB notifications in HCWs in Australia, of which 10 were born overseas, whereas in

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Karyus, Aila. "Holistic Management in Pulmonary Tuberculosis Patients with Malnutrition." Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) 6, no. 2 (2024): 35. http://dx.doi.org/10.22146/rpcpe.68872.

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Background: Tuberculosis (TB) is still a problem in developing countries and even the world. TB is one of the top 10 causes of death and the first cause of death from an infectious agent worldwide. The government plans to eliminate TB by 2030, which is carried out with the National Strategy for TB Control. Family doctors play an important role in which the role of family doctors is not only to cure but also to promote health and prevention of TB disease. Purpose: The application of evidence-based medical doctor family services to patients by identifying risk factors, clinical problems, and man

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Muhammad Alwy Arifin and Suci Rahmadani. "Health Policy Perspectives on Paediatric Tuberculosis Management: A Literature Review." Journal of Health Literacy and Qualitative Research 4, no. 1 (2024): 20–24. https://doi.org/10.61194/jhlqr.v4i1.376.

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Paediatric tuberculosis (TB) remains a significant public health challenge, particularly in low- and middle-income countries (LMICs). While TB is largely preventable and treatable, children often face barriers to timely diagnosis and appropriate treatment due to gaps in health policy and systems. This literature review examines health policy perspectives on Paediatric tuberculosis management, focusing on global and national policies, the integration of TB services into broader health systems, and the challenges of implementing effective Paediatric TB control programs. The review highlights suc

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Weldemhret, Letebrhan. "Burden of pulmonary tuberculosis and challenges related to tuberculosis detection in Ethiopia." Journal of Infection in Developing Countries 17, no. 05 (2023): 578–82. http://dx.doi.org/10.3855/jidc.13169.

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Early and rapid diagnosis of Mycobacterium tuberculosis in clinical specimen is important for the treatment of patients and control of disease transmission to the community. The disease is largely preventable and curable, but without rapid, and correct diagnostic tools for tuberculosis (TB) infection and drug resistance, it is unlikely that we can meet the national TB elimination program in Ethiopia by 2035. Moreover, drug resistant TB is becoming more common and is a great challenge for the successful control and eradication of TB. The need for rapid, accurate and affordable methods for TB ma

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Bishara, Hashem, Daniel Weiler-Ravell, Amer Saffouri, and Manfred Green. "The Challenges of Tuberculosis Management beyond Professional Competence: Insights from Tuberculosis Outbreaks among Ethiopian Immigrants in Israel." Tropical Medicine and Infectious Disease 9, no. 2 (2024): 29. http://dx.doi.org/10.3390/tropicalmed9020029.

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Controlling tuberculosis (TB) among immigrants from high-incidence countries presents a public health concern as well as a medical challenge. In this article, we investigate a TB outbreak in a community of people of Jewish descent who emigrated from Ethiopia to Israel (Israeli Ethiopians) that started in June 2022. The index case was a 20-year-old female who had recently immigrated to Israel with her family. Her pre-immigration tuberculin skin test was positive. After excluding active TB, treatment with daily isoniazid for latent TB (LTB) was started shortly after her arrival. A year later, sh

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Sireci, Guido, Francesco Dieli, Diana Di Liberto, et al. "Anti-16-Kilodalton Mycobacterial Protein Immunoglobulin M Levels in Healthy but Purified Protein Derivative-Reactive Children Decrease after Chemoprophylaxis." Clinical and Vaccine Immunology 14, no. 9 (2007): 1231–34. http://dx.doi.org/10.1128/cvi.00057-07.

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ABSTRACT Serum responses against Mycobacterium tuberculosis HSP16 were determined for children with tuberculosis (TB) and for healthy purified protein derivative (PPD)-positive and PPD-negative children. Immunoglobulin G (IgG) and IgM responses were higher for TB patients than for other groups. After chemotherapy, IgM and IgG responses decreased for TB patients and PPD-positive subjects. Monitoring of anti-M. tuberculosis HSP16 responses could assist in the management of pediatric TB.

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Zellweger, Jean-Pierre. "Tuberculosis Multidrug-resistant Tuberculosis – From Epidemiology to Treatment Design." European Respiratory & Pulmonary Diseases 01, no. 01 (2015): 20. http://dx.doi.org/10.17925/erpd.2015.01.01.20.

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Multidrug-resistant tuberculosis (MDR-TB) and extensively resistant tuberculosis (XDR-TB) are present in most regions of the world and represent a serious threat to the control of tuberculosis. They usually result from errors somewhere along the chain of management of the disease that favoured the selection of resistant mutants, progressively replacing drug-sensitive strains and transmitted to further patients. The currently recommended strategies for the control of this serious situation is the rapid identification of drug-resistant strains, careful drug management of patients with second-lin

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Andry Sulistyanto, Anggun Nilamsani, and Irawati Fatikasari. "Penambahan Kader TB Guna Mencegah Penularan Penyait TBC Di Desa Walidono Kecamatan Prajekan Kabupaten Bondowoso." Jurnal Informasi Pengabdian Masyarakat 1, no. 3 (2023): 208–13. http://dx.doi.org/10.47861/jipm-nalanda.v1i3.427.

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Cadres are a group of people who are fostered by a management agency in an organization that functions to assist the organization's tasks. Activating TB cadres is an alternative in efforts to prevent and control Tuberculosis (TB) sufferers in Walidono Village, Prajekan District, Bondowoso Regency. The activation of TB cadres will begin with mentoring activities related to procedures that will be carried out in the future in efforts to prevent and control tuberculosis (TB) sufferers. The benefit of reactivating TB cadres is the creation of efforts to help cure and reduce Tuberculosis (TB) suffe

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Lee, Elin, Srinivasan Sanjay, and Stephen Teoh. "The role of the TB T-spot test in patients with tubercular retinal vasculitis." Asian Journal of Ophthalmology 14, no. 3 (2016): 137–43. http://dx.doi.org/10.35119/asjoo.v14i3.120.

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Purpose: To report tuberculosis (TB) T-spot diagnosis and management of two cases of presumptive tubercular retinal vasculitis in Singapore.Method: Retrospective case reports.Results: Two patients were diagnosed with presumptive TB retinal vasculitis using clinical features, TB T-spot test and ancillary investigations. They were successfully treated with a combination therapy of oral steroids, anti-tuberculosis medications and pan retinal photocoagulation (PRP). Follow-up demonstrated resolution of symptoms and signs with no complications arising from anti-tuberculosis medications.Conclusions:

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Muharam, Maulana, Dewi Wahyu Firina, and Dessy Mizarti. "MULTI DRUG RESISTANT TUBERCULOSIS IN PREGNANCY." Andalas Obstetrics And Gynecology Journal 6, no. 1 (2022): 1–15. http://dx.doi.org/10.25077/aoj.6.1.1-15.2022.

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Tuberculosis can develop to multi drug resistant tuberculosis, this will be a serious health problem, not only in Indonesia, also in the world. This disease complexity, length of treatment, adverse effect of drug, make it management become challenging. Pregnancy with physiological changes in it made pregnant woman susceptible to infection, include tuberculosis infection. Data about MDR TB in pregnancy were not much, because TB screening in pregnancy were not often done, also pregnancy it self almost exclude from any trial. Because of MDR TB regiment adverse effect, much of clinician suggest wo

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Torpey, Kwasi, Adwoa Agyei-Nkansah, Lily Ogyiri, et al. "Management of TB/HIV co-infection: the state of the evidence." Ghana Medical Journal 54, no. 3 (2020): 186–96. http://dx.doi.org/10.4314/gmj.v54i3.10.

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Tuberculosis (TB) and HIV are strongly linked. There is a 19 times increased risk of developing active TB in people living with HIV than in HIV-negative people with Sub-Saharan Africa being the hardest hit region. According to the WHO, 1.3 million people died from TB, and an additional 300,000 TB-related deaths among people living with HIV. Although some progress has been made in reducing TB-related deaths among people living with HIV due to the evolution of diagnostics, treatment and antiretroviral HIV treatment, multi drug resistant TB is becoming a source of worry. Though significant progre

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Maphalle, Lehlogonolo N. F., Bozena B. Michniak-Kohn, Modupe O. Ogunrombi, and Oluwatoyin A. Adeleke. "Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?" Children 9, no. 8 (2022): 1120. http://dx.doi.org/10.3390/children9081120.

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Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness that can be fatal post-infection or even serve as reservoirs for future disease outbreaks. However, pediatric TB is the least prioritized in most health programs and optimal infection/disease control has been quite neglected for this specialized patient category, as most scientific and clinical research efforts focus on

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Wina, Djiu,, Irwanto Irwanto, Retno Asih Setyoningrum, Arda Pratama Putra Chafid, Rika Hapsari, and Nining Febriyana. "Comprehensive management for miliary tuberculosis associated with schizoaffective disorder in an adolescent female: A case report." Edelweiss Applied Science and Technology 9, no. 2 (2025): 525–34. https://doi.org/10.55214/25768484.v9i2.4518.

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Adolescents are vulnerable to tuberculosis (TB), some with severe forms like miliary TB, due to biological, psychosocial, and environmental factors. Schizoaffective disorder, though rare, adds complexity to TB management, requiring a multidisciplinary approach. This report aims to describe the comprehensive management of a 17-year-old female with miliary TB, anti-tuberculosis drug-induced hepatotoxicity (ADIH), and schizoaffective disorder, emphasizing the interplay between infectious disease and mental health. A 17-year-old female presented with shortness of breath, chronic cough, prolonged f

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Kay, Alexander W., Helena Rabie, Elizabeth Maleche-Obimbo, Moorine Penninah Sekadde, Mark F. Cotton, and Anna M. Mandalakas. "HIV-Associated Tuberculosis in Children and Adolescents: Evolving Epidemiology, Screening, Prevention and Management Strategies." Pathogens 11, no. 1 (2021): 33. http://dx.doi.org/10.3390/pathogens11010033.

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Children and adolescents living with HIV continue to be impacted disproportionately by tuberculosis as compared to peers without HIV. HIV can impact TB screening and diagnosis by altering screening and diagnostic test performance and can complicate prevention and treatment strategies due to drug–drug interactions. Post-tuberculosis lung disease is an underappreciated phenomenon in children and adolescents, but is more commonly observed in children and adolescents with HIV-associated tuberculosis. This review presents new data related to HIV-associated TB in children and adolescents. Data on th

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Rajasekaran, S., Dilip Chand Raja Soundararajan, Ajoy Prasad Shetty, and Rishi Mugesh Kanna. "Spinal Tuberculosis: Current Concepts." Global Spine Journal 8, no. 4_suppl (2018): 96S—108S. http://dx.doi.org/10.1177/2192568218769053.

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Study Design: Review article. Objectives: A review of literature on the epidemiology, diagnosis, and management of spinal tuberculosis (TB). Methods: A systematic computerized literature search was performed using Cochrane Database of Systematic Reviews, EMBASE, and PubMed. Studies published over the past 10 years were analyzed. The searches were performed using Medical Subject Headings terms, and the subheadings used were “spinal tuberculosis,” “diagnosis,” “epidemiology,” “etiology,” “management,” “surgery,” and “therapy.” Results: Tissue diagnosis remains the only foolproof investigation to

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Saha, Mitul, and Swarupa Chakole. "Assessment of the status of presentation and management of tuberculosis patients in central India." F1000Research 13 (February 16, 2024): 101. http://dx.doi.org/10.12688/f1000research.141720.1.

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Tuberculosis (TB) continues to pose a notable public health issue not just within India but on a worldwide scale. Analyzing the causes of presentation, management, and treatment delays of tuberculosis can offer valuable understanding into local trends and aid in crafting specific approaches for the successful management of TB. This research involves a cross-sectional examination conducted among TB patients residing in the regions served by the District Tuberculosis Centre, Wardha, and the directly observed treatment short course center in Sawangi. Information will be collected using a standard

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Pontali, E., M. Tadolini, and G. B. Migliori. "TB consilia and quality of tuberculosis management." International Journal of Tuberculosis and Lung Disease 23, no. 10 (2019): 1048–49. http://dx.doi.org/10.5588/ijtld.19.0423.

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