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Дисертації з теми "Vibrio cholerae"

Автор: Grafiati

Опубліковано: 4 червня 2021

Оновлено: 25 липня 2025

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1

Nygren, Erik. "A mouse model for direct evaluation of cholera vaccines /." Göteborg : Dept. of Microbiology and immunology, Institute of Biomedicine, The Sahlgrenska Academy at University of Gothenburg, 2009. http://hdl.handle.net/2077/19376.

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2

Falklind, Jerkérus Susanna. "Vibrio cholerae O139 : identification, characterization and vaccine strategies /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-696-0/.

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3

Le, Roux Wouter Jacobus. "Population dynamics of Vibrio cholerae in the Vaal Barrage." Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-02162007-175110.

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4

Occhino, Deborah Ann. "Vibrio cholerae iron transport : characterization of two tonB systems and components of a heme transport system /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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5

Chow, Ka-hang. "Molecular characterization of RTX toxin of vibrio cholerae causing epidemics." Click to view the E-thesis via HKUTO, 2001. http://sunzi.lib.hku.hk/hkuto/record/B42575898.

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6

Lee, Jason J. "Neutrophil responses to Vibrio cholerae autoinducer-1 and structural analogues." Thesis, Griffith University, 2021. http://hdl.handle.net/10072/404172.

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Анотація:

Vibrio cholerae is a pathogen responsible for cholera, an infectious disease that usually manifests as severe diarrhea. V. cholerae cells can regulate population-wide gene expression changes in a density-dependent manner, in a process known as quorum sensing (QS). QS involves communication between bacterial cells using secreted signalling molecules. V. cholerae autoinducer-1 (CAI-1) is the dominant signalling molecule in the V. cholerae QS circuit and has roles in regulating biofilm formation/degradation and expression of virulence genes. Interactions between bacterial-produced QS molecules an

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7

Moore, Sandra. "Dynamics of cholera epidemics in Haiti and Africa." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5505/document.

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Le cholera est une maladie diarrhéique aiguë due à la consommation d’eau ou d’aliments contaminés par des souches toxigéniques de Vibrio cholerae. Selon le “paradigme du choléra”, la maladie est provoquée par une exposition à un réservoir environnemental de V. cholerae avec des épidémies directement modulées par des facteurs environnementaux. Cependant, comme divers arguments plaident contre ce dogme, nous avons voulu élucider les mécanismes de la dynamique des épidémies de cholera dans trois foyers situés en Haïti, en République Démocratique du Congo (RDC) et en Afrique de l’Ouest. Nous avons

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8

Mann, Maretta Clare, and n/a. "Sialylmimetics as Potential Inhibitors fo Vibrio Cholerae Sialidase." Griffith University. Institute for Glycomics, 2004. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20061006.083947.

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Анотація:

Cholera is an epidemic infectious diarrhoeal disease that for centuries has proven its frightening ability to cause rapid and widespread loss of human life. All symptoms associated with cholera are a result of rapid dehydration due to infection by pathogenic strains of the bacterium Vibrio cholerae. The damaging effects associated with cholera are mainly attributed to the toxin, which is secreted by the bacterium and infects cells lining the gastrointestinal tract. A sialidase, also secreted by the bacterium, is believed to facilitate toxin uptake by the gastrointestinal epithelium. V. cholera

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9

Mann, Maretta Clare. "Sialylmimetics as Potential Inhibitors fo Vibrio Cholerae Sialidase." Thesis, Griffith University, 2004. http://hdl.handle.net/10072/367187.

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Анотація:

Cholera is an epidemic infectious diarrhoeal disease that for centuries has proven its frightening ability to cause rapid and widespread loss of human life. All symptoms associated with cholera are a result of rapid dehydration due to infection by pathogenic strains of the bacterium Vibrio cholerae. The damaging effects associated with cholera are mainly attributed to the toxin, which is secreted by the bacterium and infects cells lining the gastrointestinal tract. A sialidase, also secreted by the bacterium, is believed to facilitate toxin uptake by the gastrointestinal epithelium. V. cholera

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10

Zo, Young-Gun. "Phylogenomic and structural analyses of Vibrio cholerae populations and endemic cholera." College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/3090.

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Анотація:

Thesis (Ph. D.) -- University of Maryland, College Park, 2005.<br>Thesis research directed by: Marine-Estuarine-Environmental Sciences. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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11

Guidolin, Angelo. "Molecular biology of "Vibrio cholerae" bacteriophage CP-T1 and its host interactions." Title page, contents and abstract only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phg948.pdf.

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12

Cofie, Daniel Quarcoopome Guthrie Rufus K. "Effect of chitin on Vibrio cholerae /." See options below, 1988. http://proquest.umi.com/pqdweb?did=746612041&sid=1&Fmt=2&clientId=68716&RQT=309&VName=PQD.

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13

Stroher, Vive Horst. "Serotype conversion in Vibrio cholerae 01 /." Title page, contents and abstract only, 1992. http://web4.library.adelaide.edu.au/theses/09PH/09phs919.pdf.

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14

Jahan, Nasrin. "Structural studies of Vibrio cholerae quorum sensing proteins." Thesis, University of St Andrews, 2011. http://hdl.handle.net/10023/2565.

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Анотація:

The spread of cholera is always associated with contaminated food or water and this is the reason this disease has been endemic in developing countries for centuries due to their lack of proper sanitation facilities and poor or no infrastructure for sewage systems. Cholera can spread quickly and sporadically after any natural disaster that destroys the sewage system or safe drinking water supply of both developed and undeveloped countries. In Southeast Asia in December 2004 and in Pakistan and Haiti 2010, cholera outbreaks followed the natural disasters; with most of the cholera victims being

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15

Chow, Ka-hang, and 周嘉恆. "Molecular characterization of RTX toxin of vibrio cholerae causing epidemics." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B42575898.

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16

Purins, Leanne Roslyn. "Molecular characterisation of the transcriptional activator, HLYU, of Vibrio cholerae O1 /." Title page, abstract and table of contents only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09php9857.pdf.

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Thesis (Ph.D.)--University of Adelaide, School of Molecular and Biomedical Science , Discipline of Microbiology and Immunology, 2005.<br>"May, 2004" Includes corrigenda. includes bibliographical references (leaves 118-156).

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17

Bougoudogo, Fiabou. "Contribution à l'étude de l'immunité protectrice contre le choléra : rôle des anticorps vibriocides reconnaissant le polysaccharide spécifique du lipopolysaccharide de "Vibrio cholerae" O:1." Paris 11, 1994. http://www.theses.fr/1994PA114831.

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18

Sheikh, Md Arif. "Structural biology of Vibrio cholerae pathogenicity factors." Thesis, St Andrews, 2009. http://hdl.handle.net/10023/696.

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19

Focareta, Tony. "The extracellular DNase(s) of vibrio cholerae /." Title page, abstract and table of contents only, 1989. http://web4.library.adelaide.edu.au/theses/09PH/09phf652.pdf.

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20

Sharma, Dharam Pal. "Non-lipopolysaccharide protective antigens of Vibrio cholerae /." Title page, abstract and contents only, 1990. http://web4.library.adelaide.edu.au/theses/09PH/09phs5314.pdf.

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21

Findlay, Gordon. "Biogenesis of virulence factors in Vibrio cholerae." Thesis, University of Kent, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294636.

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22

Berg, Thorsten. "Virulenzregulationskaskade und Chitobiose-Metabolismus in Vibrio cholerae." Doctoral thesis, kostenfrei, 2008. http://www.opus-bayern.de/uni-wuerzburg/volltexte/2008/2829/.

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23

Ogierman, Monica A. "Molecular characterisation of the fungus Corynespora cassicola /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09pho344.pdf.

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24

Mutreja, Ankur. "The origins and evolution of Vibro cholerae O1 E1 Tor." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648490.

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25

Edwin, Aaron. "Structural and functional studies of the secreted metalloprotease PrtV from Vibrio cholerae." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-84553.

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Анотація:

Cholera, an acute diarrheal diseases caused by the intestinal infection of the pathogenic bacterium Vibrio cholerae, continues to be a global killer in the world today. PrtV, a secreted zinc metalloprotease, is a potent cytotoxic virulence factor of V. cholerae. The 102 kDa full length multi-domain PrtV protein undergoes several N and C terminal modifications before being secreted as a 81 kDa pro-protein. The activation of the pro-protein is calcium dependent. The removal of calcium triggers auto-proteolysis to give a stable active protease with the catalytic zinc binding domain. The aim of th

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26

Wennberg, Aina Charlotte. "PCR-detection of Vibrio cholerae in ballast water." Thesis, Norwegian University of Science and Technology, Department of Biotechnology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-6883.

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27

Lindmark, Barbro. "Modulators of Vibrio cholerae predator interaction and virulence." Doctoral thesis, Umeå universitet, Molekylärbiologi (Medicinska fakulteten), 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-30211.

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Анотація:

Vibrio cholerae, the causal agent of cholera typically encodes two critical virulence factors: cholera toxin (CT), which is primarily responsible for the diarrhoeal purge, and toxin-co-regulated pilus (TCP), an essential colonisation factor. Nontoxigenic strains expressing TCP can efficiently acquire the CT gene through lysogenic conversion with CTXΦ, a filamentous phage that encodes CT and uses TCP as a receptor. V. cholerae is a Gram-negative bacterium and a natural inhabitant of estuarine and coastal waters throughout both temperate and tropical regions of the world. In the aquatic environ

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28

Saul-McBeth, Jessica. "Characterization of SipA, A Protein Important for Stress Responses in Vibrio cholerae." University of Toledo Health Science Campus / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1544540466901883.

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29

Ha, Thi Quyen, and Duy Khang Dinh. "The changes in antigenic components of Vibrio cholerae strains isolated in Vietnam." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-190840.

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Whole cells of Vibrio cholerare serotype Inaba and serotype Ogawa (strains I389 and O395) were injected into rabbits to obtain antiserum. The antiserums were used for immune reaction with antigenic components of 25 strains of V.cholerae isolated from five provinces of Vietnam and the two standard strains I389 and O395 by Western-blot technique. Analysis of immune hybrid results showed that there were 11 antigenic components with molecular weights approximately 79kDa, 62kDa, 52kDa, 45kDa, 42kDa, 38kDa, 35kDa, 31kDa, 26kDa, 23kDa and 20kDa. In which the antigens of 45kDa, 42kDa, 31kDa and 20kDa

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30

Midonet, Caroline. "Mécanisme d'intégration du phage TLC dans le génome de Vibrio cholerae." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS314/document.

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Анотація:

La plupart des bactéries ont un unique chromosome circulaire. Lors de la réplication de l’ADN, la circularité lie topologiquement les deux chromatides sœurs résultant de la réplication (caténanes et dimères). Ces liens topologiques doivent être résolus afin de permettre une bonne ségrégation de l’information génétique entre les deux cellules filles au cours de la division cellulaire. Les bactéries possèdent une machinerie très conservée: les recombinases à tyrosines XerC et XerD, capables de résoudre les dimères et une partie des caténanes, en catalysant un crossover au site spécifique dif sit

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31

Yam, Wing-cheong. "Molecular epidemiology of enterotoxigenic escherichia coli and vibrio cholerae in Hong Kong /." [Hong Kong : University of Hong Kong], 1990. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12966381.

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32

Ha, Thi Quyen, and Duy Khang Dinh. "The changes in antigenic components of Vibrio cholerae strains isolated in Vietnam: Research article." Technische Universität Dresden, 2014. https://tud.qucosa.de/id/qucosa%3A29114.

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Анотація:

Whole cells of Vibrio cholerare serotype Inaba and serotype Ogawa (strains I389 and O395) were injected into rabbits to obtain antiserum. The antiserums were used for immune reaction with antigenic components of 25 strains of V.cholerae isolated from five provinces of Vietnam and the two standard strains I389 and O395 by Western-blot technique. Analysis of immune hybrid results showed that there were 11 antigenic components with molecular weights approximately 79kDa, 62kDa, 52kDa, 45kDa, 42kDa, 38kDa, 35kDa, 31kDa, 26kDa, 23kDa and 20kDa. In which the antigens of 45kDa, 42kDa, 31kDa and 20kDa

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33

David, Ariane. "Chorégraphie de ségrégation des deux chromosomes de Vibrio cholerae." Phd thesis, Université Paris Sud - Paris XI, 2013. http://tel.archives-ouvertes.fr/tel-00921394.

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L'objectif de cette thèse est de définir la chorégraphie de ségrégation des deux chromosomes circulaires de Vibrio cholerae, c'est à dire le positionnement de l'information génétique au cours de la croissance de la cellule, ainsi que les mécanismes dirigeant ces ségrégations. Il a longtemps été supposé que les bactéries étaient trop petites pour avoir une organisation intra-cellulaire, et le manque de techniques appropriées ne permettait pas d'infirmer cette hypothèse. Or la taille des chromosomes comparée à celle de la bactérie impose une compaction et aujourd'hui, de nouvelles techniques de

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34

O'Neal, Claire J. "Structural studies of the cholera toxin catalytic subunit /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/8592.

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35

Toribio, Isaías Luis Daniel. "Signal Transduction proteins in Streptococcus pneumoniae and Vibrio cholerae." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/668345.

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The aim of this project is to structurally characterize proteins involved in bacterial signal transduction systems by applying X-ray crystallography. Bacteria use signal transduction systems to react in response to any environmental changes detected. Bacterial signal transduction is divided into two categories, one- component systems and two-component systems. Two-component systems are composed by a Response Regulator (RR) and a Histidine Kinase (HK); the Histidine Kinase auto phosphorylates an inner domain, and soon after, it phosphorylates the receiver domain on the Response Regulator, ac

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36

Choopun, Nipa. "The population structure of Vibrio cholerae in Chesapeake Bay." College Park, Md. : University of Maryland, 2004. http://hdl.handle.net/1903/1686.

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Анотація:

Thesis (Ph. D.) -- University of Maryland, College Park, 2004.<br>Thesis research directed by: Marine-Estuarine-Environmental Sciences. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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37

Humphreys, Sue. "Isolation and characterisation of a Vibrio cholerae ompR homologue." Thesis, University of Leicester, 1997. http://hdl.handle.net/2381/30363.

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Анотація:

Vibrio cholerae is the pathogenic agent of the diarrhoeal disease cholera and the major determinant of the disease is the elaboration by the bacteria of the potent enterotoxin cholera toxin (CT). In order to successfully colonise a host V. cholerae must co-ordinately regulate the expression of genes necessary for survival and virulence. ToxR regulates the expression of 17 virulence genes including CT in response to environmental signals like temperature, pH and osmolarity. The change in environment from the external to the human host activates ToxR and the expression of virulence genes under i

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38

Sabharwal, Dharmesh. "Regulatory roles of sRNAs in pathogenesis of Vibrio cholerae." Doctoral thesis, Umeå universitet, Institutionen för molekylärbiologi (Medicinska fakulteten), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100528.

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The Gram-negative pathogen Vibrio cholerae uses variety of regulatory molecules to modulate expression of virulence factors. One important regulatory element of microorganisms is small non-coding RNAs (sRNAs), which control various cell functions such as expression of cell membrane proteins, mRNA decay and riboswitches. In this thesis studies, we demonstrated the roles of the sRNAs VrrA in regulation of outer membrane protein expression, biofilm formation and expression of ribosome binding proteins. In addition, we showed that VrrB, a newly discovered sRNA, played a role in amino acid dependen

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39

Massam-Wu, Teresa. "Characterisation of the Vibrio cholerae antibiotic resistance var operon." Thesis, Durham University, 2007. http://etheses.dur.ac.uk/2562/.

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The discovery and use of antibiotics in the chemotherapy of bacterial infections has revolutionised medicine as it is today. Unfortunately, the progressive use of antibiotics has promoted the evolution of bacterial defences against these mediators and thus the emergence of antibiotic resistance. Multidrug resistance (MDR) in bacterial pathogens has grown with such rapid progression that it now threatens to compromise the effective chemotherapy of a plethora of diseases. This thesis aspires to elucidate the molecular resistance mechanisms adopted by these bacteria, in order to expand our knowle

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40

Bomchil, Natalia. "Régulation de la formation de biofilms chez Vibrio cholerae." Paris 7, 2002. http://www.theses.fr/2002PA077030.

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41

Mitchell, Daniel David. "Cholera toxin inhibition and EpsF from its secretion system /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/9210.

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42

Franzon, Vicki L. "Haemagglutinins of Vibrio cholerae : molecular characterization of the mannose-fucose resistant haemagglutinin (MFRHA) /." Title page, abstract and contents only, 1988. http://web4.library.adelaide.edu.au/theses/09PH/09phf837.pdf.

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43

Antonova, Elena S. "The regulatory network controlling natural competence for DNA uptake in Vibrio cholerae." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/47626.

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Анотація:

The bacterial pathogen Vibrio cholerae is responsible for ongoing cholera outbreaks in Haiti and elsewhere. Association of V. cholerae with the human host is responsible for fatal disease, but the bacteria also reside as natural inhabitants of aquatic environments, commonly attaching as biofilms to chitinous surfaces of copepods and crabs. Prior studies in V. cholerae demonstrated that competence for genetic transformation, a mechanism of horizontal gene transfer (HGT), requires the TfoX regulator protein that is triggered by chitin, and the HapR transcription factor that is made in response t

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44

Yáñez, Marissa Elena. "Structural and functional studies of minor pseudopilins from the type 2 secretion system of Vibrio cholerae /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8086.

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45

Lin, Po-Chi. "Na⁺-translocating NADH:Quinone oxidoreductases from Vibrio cholerae and Yarrowia lipolytica /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17541.

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46

Farfán, Sellarés Maribel. "Estudio de la estructura genética de poblaciones de "Vibrio cholerae"." Doctoral thesis, Universitat de Barcelona, 2002. http://hdl.handle.net/10803/2415.

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Анотація:

Se ha estudiado la variabilidad genética de poblaciones de <i>V. cholerae</i> procedentes de distintas fuentes y orígenes geográficos, que agrupan diferentes serogrupos y biotipos de esta especie. Se ha analizado la variabilidad genética a dos niveles: a un nivel proteico, aplicando la técnica de electroforesis de aloenzimas multilocus (MLEE), y a un nivel génico, realizando el análisis de secuencias multilocus (MLST). Con ello, se ha intentado determinar la relación genética existente entre las distintas cepas estudiadas, considerando los datos obtenidos globalmente y por subgrupos de poblaci

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47

Rawlings, Tonya Kafi. "Interactions of Vibrio cholerae serogroups O1 and O139 and copepods." College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/2865.

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Анотація:

Thesis (Ph. D.) -- University of Maryland, College Park, 2005.<br>Thesis research directed by: Marine-Estuarine-Environmental Sciences. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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48

Iredell, J. R. "Molecular export and pilin assembly : TCP biogenesis in Vibrio cholerae /." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phi648.pdf.

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49

Resch, Craig. "Biochemistry and physiology of NhaP-type antiporters in Vibrio cholerae." Elsevier, 2010. http://hdl.handle.net/1993/31098.

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Antiporters that exchange alkali cations (Na+ or K+) for protons play an important role in the physiology of all known bacterial species. They are involved in regulating intracellular pH and maintaining cellular volume as well as the formation of a chemical Na+ gradient across the membrane, which is important to many bacteria as an energy source for processes such as accumulation of substrates, ATP synthesis, and flagellar rotation. Another important role of cation/proton antiporters is homeostasis of intracellular cation content. The situation of a thermodynamic equilibrium of Na+ or K+ on t

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50

Alm, Richard A. "Molecular characterization of the haemolysin determinant of Vibrio cholerae O1 /." Title page, contents and abstract only, 1989. http://web4.library.adelaide.edu.au/theses/09PH/09pha444.pdf.

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Thesis (Ph. D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1990.<br>Includes an appendix of author's previously published papers. Includes bibliographical references (leaves 123-160).

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