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Статті в журналах з теми "Xenobiotic organic compounds"

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Lindblom, E., K. V. Gernaey, M. Henze, and P. S. Mikkelsen. "Integrated modelling of two xenobiotic organic compounds." Water Science and Technology 54, no. 6-7 (September 1, 2006): 213–21. http://dx.doi.org/10.2166/wst.2006.620.

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This paper presents a dynamic mathematical model that describes the fate and transport of two selected xenobiotic organic compounds (XOCs) in a simplified representation of an integrated urban wastewater system. A simulation study, where the xenobiotics bisphenol A and pyrene are used as reference compounds, is carried out. Sorption and specific biological degradation processes are integrated with standardised water process models to model the fate of both compounds. Simulated mass flows of the two compounds during one dry weather day and one wet weather day are compared for realistic influent flow rate and concentration profiles. The wet weather day induces resuspension of stored sediments, which increases the pollutant load on the downstream system. The potential of the model to elucidate important phenomena related to origin and fate of the model compounds is demonstrated.
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Foroozesh, Maryam, Jayalakshmi Sridhar, Navneet Goyal, and Jiawang Liu. "Coumarins and P450s, Studies Reported to-Date." Molecules 24, no. 8 (April 24, 2019): 1620. http://dx.doi.org/10.3390/molecules24081620.

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Cytochrome P450 enzymes (CYPs) are important phase I enzymes involved in the metabolism of endogenous and xenobiotic compounds mainly through mono-oxygenation reactions into more polar and easier to excrete species. In addition to their role in detoxification, they play important roles in the biosynthesis of endogenous compounds and the bioactivation of xenobiotics. Coumarins, phytochemicals abundant in food and commonly used in fragrances and cosmetics, have been shown to interact with P450 enzymes as substrates and/or inhibitors. In this review, these interactions and their significance in pharmacology and toxicology are discussed in detail.
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Byrns, Geoff. "The fate of xenobiotic organic compounds in wastewater treatment plants." Water Research 35, no. 10 (July 2001): 2523–33. http://dx.doi.org/10.1016/s0043-1354(00)00529-7.

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Pedersen, Joel A., Matt A. Yeager, and I. H. (Mel) Suffet. "Xenobiotic Organic Compounds in Runoff from Fields Irrigated with Treated Wastewater." Journal of Agricultural and Food Chemistry 51, no. 5 (February 2003): 1360–72. http://dx.doi.org/10.1021/jf025953q.

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NICOLELLA, C., M. ZOLEZZI, M. RABINO, M. FURFARO, and M. ROVATTI. "Development of particle-based biofilms for degradation of xenobiotic organic compounds." Water Research 39, no. 12 (July 2005): 2495–504. http://dx.doi.org/10.1016/j.watres.2005.04.016.

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Li, Jiuyi, Lele Qin, Lei Zhao, Aimin Wang, Yong Chen, Liao Meng, Zhongguo Zhang, Xiujun Tian, and Yanmei Zhou. "Removal of Refractory Organics from Biologically Treated Landfill Leachate by Microwave Discharge Electrodeless Lamp Assisted Fenton Process." International Journal of Photoenergy 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/643708.

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Biologically treated leachate usually contains considerable amount of refractory organics and trace concentrations of xenobiotic pollutants. Removal of refractory organics from biologically treated landfill leachate by a novel microwave discharge electrodeless lamp (MDEL) assisted Fenton process was investigated in the present study in comparison to conventional Fenton and ultraviolet Fenton processes. Conventional Fenton and ultraviolet Fenton processes could substantially remove up to 70% of the refractory organics in a membrane bioreactor treated leachate. MDEL assisted Fenton process achieved excellent removal performance of the refractory components, and the effluent chemical oxygen demand concentration was lower than 100 mg L−1. Most organic matters were transformed into smaller compounds with molecular weights less than 1000 Da. Ten different polycyclic aromatic hydrocarbons were detected in the biologically treated leachate, most of which were effectively removed by MDEL-Fenton treatment. MDEL-Fenton process provides powerful capability in degradation of refractory and xenobiotic organic pollutants in landfill leachate and could be adopted as a single-stage polishing process for biologically treated landfill leachate to meet the stringent discharge limit.
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Küblbeck, Jenni, Jonna Niskanen, and Paavo Honkakoski. "Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR." Cells 9, no. 10 (October 15, 2020): 2306. http://dx.doi.org/10.3390/cells9102306.

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During the last two decades, the constitutive androstane receptor (CAR; NR1I3) has emerged as a master activator of drug- and xenobiotic-metabolizing enzymes and transporters that govern the clearance of both exogenous and endogenous small molecules. Recent studies indicate that CAR participates, together with other nuclear receptors (NRs) and transcription factors, in regulation of hepatic glucose and lipid metabolism, hepatocyte communication, proliferation and toxicity, and liver tumor development in rodents. Endocrine-disrupting chemicals (EDCs) constitute a wide range of persistent organic compounds that have been associated with aberrations of hormone-dependent physiological processes. Their adverse health effects include metabolic alterations such as diabetes, obesity, and fatty liver disease in animal models and humans exposed to EDCs. As numerous xenobiotics can activate CAR, its role in EDC-elicited adverse metabolic effects has gained much interest. Here, we review the key features and mechanisms of CAR as a xenobiotic-sensing receptor, species differences and selectivity of CAR ligands, contribution of CAR to regulation hepatic metabolism, and evidence for CAR-dependent EDC action therein.
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Schulten, Hans-Rolf. "Interactions of dissolved organic matter with xenobiotic compounds: Molecular modeling in water." Environmental Toxicology and Chemistry 18, no. 8 (August 1999): 1643–55. http://dx.doi.org/10.1002/etc.5620180806.

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Swindoll, C. Michael, C. Marjorie Aelion, Durell C. Dobbins, Ou Jiang, Sharon C. Long, and Frederic K. Pfaender. "Aerobic biodegradation of natural and xenobiotic organic compounds by subsurface microbial communities." Environmental Toxicology and Chemistry 7, no. 4 (April 1988): 291–99. http://dx.doi.org/10.1002/etc.5620070405.

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Top, Eva M., and Dirk Springael. "The role of mobile genetic elements in bacterial adaptation to xenobiotic organic compounds." Current Opinion in Biotechnology 14, no. 3 (June 2003): 262–69. http://dx.doi.org/10.1016/s0958-1669(03)00066-1.

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Дисертації з теми "Xenobiotic organic compounds"

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Braga, Juliana Kawanishi. "Caracterização microbiana e degradação de surfactante aniônico em reator anaeróbio de leito fluidificado com água residuária de lavanderia." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/18/18138/tde-27082014-094745/.

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Neste estudo avaliou-se a remoção e degradação de surfactante aniônico linear alquilbenzeno sulfonado (LAS) e compostos orgânicos xenobióticos em água residuária de lavanderia comercial em reator anaeróbio de leito fluidificado (RALF) preenchido com areia como material suporte, em escala de bancada (1,2 L), bem como a comunidade microbiana do biofilme e biomassa do separador de fases ao final da operação. O reator foi inoculado com lodo proveniente de reator UASB utilizado no tratamento de dejetos de suinocultura e alimentado com substrato sintético acrescido de água residuária de lavanderia comercial. Caracterização da água residuária, análises de monitoramento da concentração de LAS e matéria orgânica, além de outros parâmetros físico-químicos foram realizadas durante as etapas de operação do sistema. Essa operação foi dividida em cinco etapas: I adaptação da biomassa (575±28mg.L-1 de DQO), II (9,5±3 mg.L-1 de LAS e 637±80mg.L-1 de DQO), III (23,3±8mg.L-1 de LAS e 686±92 mg.L-1 de DQO), IV (21,7±10mg.L-1 de LAS e 691±103 mg.L-1 de DQO), V (27,9±9,6mg.L-1 de LAS e 666±161mg.L-1 de DQO). Aplicação das técnicas de PCR/DGGE e pirosequenciamento da região do rRNA 16S foi realizada para constatar a diversidade microbiana nas etapas IV (com sacarose) e V (sem sacarose). Por meio da caracterização da água residuária de lavanderia comercial foi evidenciado grande variação na concentração de diversos parâmetros, principalmente matéria orgânica (704 mg.L-1 a 4.830 mg.L-1) e LAS (12,2 mg.L-1 a 11.949 mg.L-1). A eficiência média de remoção de matéria orgânica e LAS foi 88% e 60%, respectivamente, durante toda operação do reator. As populações dos Domínios Archaea e Bacteria foram 54% e 45%, similares, respectivamente, para a biomassa da Etapa IV e Etapa V. Por meio da análise de pirosequenciamento das amostras das Etapas IV e V da areia e separador de fases do reator foram identificados 92 gêneros dos quais 24 foram relacionados com a degradação de LAS (Bdellovibrio, Ferruginibacter, Gemmatimonas, etc.).
In this study the removal and degradation of anionic surfactant linear alkylbenzene sulfonate (LAS) and xenobiotic organic compounds in a commercial laundry wastewater was evaluated in anaerobic fluidized bed reactor (AFBR) filled with sand as support material, in a bench scale (1, 2 L), as well as the microbial community of the biofime and phase separator biomass at the end of the operation. The reactor was inoculated with sludge from a UASB reactor used in the swine manure treatment and fed with synthetic substrate plus commercial laundry wastewater. Wastewater characterisation, monitoring analyzes of LAS, organic matter and other physico-chemical parameters were performed during the stages of system operation. This operation was divided into five stages: Stage I - biomass adaptation (575 ± 28mg L-1 of COD), Stage II (9.5 ± 3 mg L-1 of LAS and 637 ± 80 mg L-1 of COD ), Stage III (23.3 ± 8 mg L-1 of LAS and 686 ± 92 mg L-1 of COD), Stage IV (21.7 ± 10 mg L-1 of LAS and 691 ± 103 mg L-1 of COD), Stage V (27.9 ± 9.6 mg L-1 of LAS and 666 ± 161 mg L-1 of COD). Application of PCR/DGGE and pyrosequencing of the 16S rRNA region was performed to verify the microbial diversity in the operational phase IV (with sucrose) and V (without sucrose). Through the commercial laundry wastewater characterization a wide variation in several parameters concentration was shown, mainly organic matter (704mg L-1 to 4.830mg L-1) and LAS (12.2mg L-1 to 11.949mg L-1). The average removal efficiency of organic matter and LAS was 88% and 60%, respectively, throughout the reactor operation. The populations of the Archaea and Bacteria Domains were 54% and 45% similar, respectively, for Stages IV and V biomass. By pyrosequencing analysis of sand and phase separator samples from the Stages IV and V, 92 genera of which 24 were related to the degradation of LAS (Bdellovibrio, Ferruginibacter, Gemmatimonas, Holophaga, Magnetospirillum, Zoogloea, etc.) were identified.
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Ghalajkhani, Rosita. "Fate Modeling of Xenobiotic Organic Compounds (XOCs) in Wastewater Treatment Plants." Thesis, 2013. http://hdl.handle.net/10012/8037.

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Xenobiotic Organic Compounds (XOCs) are present in wastewater and wastewater-impacted environmental systems. Pharmaceuticals and personal care products are a broad and varied category of chemicals that are included among these compounds. Although, these compounds have been detected at low levels in surface water, concerns that these compounds may have an impact on human health and aquatic life, have led to increased interest in how XOCs are removed during wastewater treatment. Recognizing specific mechanisms in recent literature and simulating those mechanisms responsible for the removal of XOCs is the main objective of this study. Conventional models, such as the popular activated sludge models (ASM1, ASM2, etc), do not sufficiently address the removal processes; therefore, a fate model is created to provide a means of predicting and simulating removal mechanisms along with experimental analyses. GPS-X is a multi-purpose modeling tool for the simulation of municipal and industrial wastewater treatment plants. This software package includes conventional models as built-in libraries, which can be used as bases on which new models can be created. In this thesis, the removal mechanisms of XOCs are recognized and investigated; a new library for GPS-X is also created to include XOCs. As a first step the uncalibrated fate model, which includes all mechanisms of interest with their process rates and state variables, is developed using in GPS-X software. A modified ASM1 (Mantis model) is used as a basis for developing the fate model. Since only a group of mechanisms is responsible for the removal of each compound the mechanisms are categorized in three different case studies as the next step. Thus, one submodel is associated with each case study. The model developer toolbar in GPS-X software is used to develop the model for these case studies. The first case study involves the removal of antibiotics, such as Sulfamethoxazole. The removal mechanisms used in this case are biodegradation, sorption, and parent compound formation, with co-metabolism and competitive inhibition effects being inserted into the structure of the model. Secondly, the removal of nonylphenol ethoxylates (NPEOs) occurs through abiotic oxidative cleavage, hydrolysis, and biodegradation. The third case study includes removal mechanisms of biodegradation and sorption for neutral and ionized compounds. In the calibration process, model parameters are tuned such that the model can best simulate the experimental data using optimization methods. A common error criterion is Sum of Squared Errors (SSE) between the simulated results and the measured data. By minimizing SSE, optimal values of parameters of interest can be estimated. In each case study different data sets were used for the validation process. To validate the calibrated model, simulated results are compared against experimental data in each case study. The experimental data set used in the validation process is different from that used for calibrating the model, which means the validation process data set was obtained from the different literature. By looking at the validation results, it is concluded that the proposed model successfully simulates removal of XOCs. Since the operating parameters of wastewater treatment plants, such as Solids Retention Time (SRT) and Hydraulic Retention Time (HRT) are crucial for the fate of XOC???s, a sensitivity analysis is carried out to investigate the effect of those parameters. Moreover, the pH effect is studied because it relates to the ionized XOCs. Sensitivity analysis results show that the fate model is more sensitive to model parameters i.e. biodegradation rate constant (kb) than the operational parameters, i.e. SRT and HRT. Furthermore, the responses showed sensitivity to pH, whereby acidic conditions provide a better environment for removing neutral forms and alkaline conditions were suitable for removing ionized forms, according to the ionized compound fate model.
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Longstaffe, James Gregory. "A Molecular-level Investigation of the Interactions between Organofluorine Compounds and Soil Organic Matter using Nuclear Magnetic Resonance Spectroscopy." Thesis, 2013. http://hdl.handle.net/1807/35886.

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In this dissertation, the intermolecular interactions between soil organic matter (SOM) and organofluorine compounds have been studied at the molecular-level using Nuclear Magnetic Resonance (NMR) spectroscopy. NMR probes the local magnetic environment surrounding atomic nuclei, and is uniquely capable as an analytical tool to probe molecular environments in complex disordered materials, such as soils. Several NMR techniques were employed in this work, including Pulse Field Gradient (PFG)-NMR based diffusion measurements, solid-state cross-polarization (CP), saturation transfer difference (STD) spectroscopy, and reverse-heteronuclear saturation transfer difference (RHSTD) spectroscopy. Using organofluorine compounds as molecular probes, xenobiotic interactions with SOM were studied. Using 1H{19F} RHSTD, the interaction sites in humic acid for organofluorine compounds were identified by direct molecular-level methods. Protein and lignin were identified as major binding sites, with different preferences exhibited for these sites by dissimilar organofluorine compounds: aromatic organofluorine compounds display varied preference for aromatic humic acid sites while perfluorooctanoic acid exhibits near total selectivity for protein-derived binding sites. The mechanisms underlying these preferences were probed in the solution state. Using crucial knowledge from the humic acid studies, a detailed molecular-level investigation of xenobiotic interactions in an intact and unmodified whole soil was made possible. A direct and in situ elucidation of the components in soil organic matter that interact with small organofluorine xenobiotic molecules has been presented, allowing, for the first time, resolution of multiple interactions occurring for xenobiotics simultaneously at different sites within a whole soil.
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Книги з теми "Xenobiotic organic compounds"

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IMTOX-Workshop (2nd 1992 Fraunhofer-Institut für Atmosphärische Umweltforschung). Volatile organic pollutants: Levels, fate, and ecotoxicological impacts : proceedings of the 2nd IMTOX-Workshop held on Dec. 10-11, 1992, at the Fraunhofer Institute for Atmospheric Environmental Research (IFU), Garmisch-Partenkirchen, FRG. Garmisch-Partenkirchen: The Institute, 1993.

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Gut, Ivan, and Miroslav Cikrt. Industrial and Environmental Xenobiotics: Metabolism and Pharmacokinetics of Organic Chemicals and Metals Proceedings of an International Conference ... 27-30 May 1980. Springer, 2011.

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Volatile organic pollutants: Levels, fate, and ecotoxicological impacts : Proceedings of the 2nd IMTOX-Workshop held on Dec. 10-11, 1992, at the Fraunhofer ... FRG (IFU Schriftenreihe). The Institute, 1993.

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Частини книг з теми "Xenobiotic organic compounds"

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Chabukdhara, Mayuri, Sanjay Kumar Gupta, Faiz Ahmad Ansari, Amit K. Bajhaiya, and Manish Kumar. "Bioremediation of Organic Xenobiotics from Wastewater." In Microbial Biodegradation of Xenobiotic Compounds, 111–34. Boca Raton, FL : CRC Press, [2018] | “A science publishers book.”: CRC Press, 2019. http://dx.doi.org/10.1201/b22151-7.

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Sharpe, Jessica E., and Andrew Ogram. "Interactions Between Nonpolar Compounds and Soil Organic Carbon Under Low Redox Potentials." In Microbial Biodegradation of Xenobiotic Compounds, 228–40. Boca Raton, FL : CRC Press, [2018] | “A science publishers book.”: CRC Press, 2019. http://dx.doi.org/10.1201/b22151-12.

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Noman, Efaq Ali, Adel Ali Saeed Al-Gheethi, Balkis A. Talip, Radin Maya Saphira Radin Mohamed, H. Nagao, and Amir Hashim Mohd Kassim. "Xenobiotic Organic Compounds in Greywater and Environmental Health Impacts." In Management of Greywater in Developing Countries, 89–108. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-90269-2_5.

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Elektorowicz, Maria, Lin Ju, and Jan A. Oleszkiewicz. "Bioavailability of Xenobiotic Organic Compounds to Remediate Soil Containing Clay Fractions." In Bioavailability of Organic Xenobiotics in the Environment, 349–76. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-015-9235-2_18.

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Lofrano, Giusy, Anastasia Nikolaou, Maria Kostopoulou, Giovanni Pagano, Vincenzo Belgiorno, and Rodolfo Maria Alessandro Napoli. "Occurrence and Measurements of Organic Xenobiotic Compounds in Harbour and Coastal Sediments." In Xenobiotics in the Urban Water Cycle, 129–45. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-3509-7_7.

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Ghosh, Pooja, Mayank Krishna, Mihir Tanay Das, and Indu Shekhar Thakur. "Bioremediation and Detoxification of Xenobiotic Organic Compounds in Landfill Leachate by Pseudomonas sp. ISTDF1." In Management of Water, Energy and Bio-resources in the Era of Climate Change: Emerging Issues and Challenges, 225–34. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-05969-3_18.

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Noman, Efaq Ali, Adel Ali Saeed Al-Gheethi, Balkis A. Talip, Radin Maya Saphira Radin Mohamed, H. Nagao, Amir Hashim Mohd Kassim, and Junita Abdul Rahman. "Bioremediation of Xenobiotic Organic Compounds in Greywater by Fungi Isolated from Peatland, a Future Direction." In Management of Greywater in Developing Countries, 163–83. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-90269-2_9.

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Wittich, R. M. "Biodegradability of Xenobiotic Organic Compounds Depends on their Chemical Structure and Efficiently Controlled, and Productive Biochemical Reaction Mechanisms." In Biodegradability Prediction, 7–16. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-011-5686-8_2.

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Harms, H. "The Use of Laboratory Model Systems to Elucidate the Mechanisms of Bioavailability of Hydrophobic Organic Compounds." In Bioavailability of Organic Xenobiotics in the Environment, 121–34. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-015-9235-2_7.

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Fernando, Eustace, Godfrey Kyazze, Ahmed Ahsan, and Pavithra Fernando. "Expedited Biodegradation of Organic Pollutants and Refractory Compounds Using Bio-Electrochemical Systems." In Biodegradation [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99229.

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Biodegradation of xenobiotics is often considered to be a slow process. This is especially true if the xenobiotic in question is polymeric in nature, contains many chemical substituent groups or generally exhibits high level of toxicity to environmental microbiota. Due to this observed slow kinetics of degradation, removal of many xenobiotics from contaminated environments using conventional bioremediation technologies is a difficult problem. To alleviate this, alternative technologies showing improved kinetics of biodegradation are sought by the scientific community. One such promising approach is the usage of the novel technology of bio-electrochemical systems for improved degradation of xenobiotics. Due to the newness of this technology and affiliated methods, not much information about its usage for biodegradation of xenobiotics is available in literature. Therefore, this chapter aims to address that gap and bring about a comprehensive analysis on the usage of bio-electrochemical systems for rapid removal of xenobiotic contaminants from the environment.
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Звіти організацій з теми "Xenobiotic organic compounds"

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Gschwend, Philip M., and Ken O. Buesseler. Xenobiotic Organic Compound Cycling in Coastal Waters. Fort Belvoir, VA: Defense Technical Information Center, September 1997. http://dx.doi.org/10.21236/ada634638.

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