Academic literature on the topic 'Α-hydroxyphosphonates'

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Journal articles on the topic "Α-hydroxyphosphonates"

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Milen, Mátyás, Tamás Miklós John, Anna Sára Kis та ін. "Synthesis and Cytotoxic Activity of a New Family of α-Hydroxyphosphonates with the Benzothiophene Scaffold". Pharmaceuticals 18, № 7 (2025): 949. https://doi.org/10.3390/ph18070949.

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Background: α-Hydroxyphosphonates, one of the most prominent classes of phosphonates, remain of utmost importance because of their potential and real biological activity as pharmaceutical or pesticide agents. The effect is the consequence of their enzyme inhibitory properties. Objectives: It was planned to make available new heterocyclic hydroxyphosphonate derivatives with cytotoxic activity. Methods: After optimizing the synthesis, 23 members of a new family, α-hydroxy-α-(benzothiophen-2-yl)-methylphosphonates, were prepared by the Pudovik reaction of benzo[b]thiophene-2-carboxaldehydes and d
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Davletshin, R. R., A. N. Sedov, N. V. Davletshina, et al. "Catalysis of the Abramov Reaction under Conditions of Microwave Activation." Журнал физической химии 97, no. 7 (2023): 960–64. http://dx.doi.org/10.31857/s0044453723070063.

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Two series of α-hydroxyphosphonate synthesis according to the Abramov reaction are conducted under conditions of microwave activation. Acidic and basic catalysts are used along with 4-bromobenzaldehyde and 3-methoxy-4-hydroxybenzaldehyde. O,O-Diethylphosphite is used as a phosphorylating agent. The conversion of the reaction products is monitored via NMR spectroscopy. The optimum conditions for the synthesis of α-hydroxyphosphonates are selected. The crystal structure of reaction product O,O‑diethyl((4-bromophenyl(hydroxy)methyl)phosphonate 2, which crystallizes in the space group P21/n and is
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Cybulska, Pola, Yves-Marie Legrand, Alicja Babst-Kostecka та ін. "Green and Effective Preparation of α-Hydroxyphosphonates by Ecocatalysis". Molecules 27, № 10 (2022): 3075. http://dx.doi.org/10.3390/molecules27103075.

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A green and effective approach for the synthesis of structurally diversed α-hydroxyphosphonates via hydrophosphonylation of aldehydes under solventless conditions and promoted by biosourced catalysts, called ecocatalysts “Eco-MgZnOx” is presented. Ecocatalysts were prepared from Zn-hyperaccumulating plant species Arabidopsis halleri, with simple and benign thermal treatment of leaves rich in Zn, and without any further chemical treatment. The elemental composition and structure of Eco-MgZnOx were characterized by MP–AES, XRPD, HRTEM, and STEM–EDX techniques. These analyses revealed a natural r
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Pallikonda, Gangaram, Manab Chakravarty та Manoj K. Sahoo. "An easy access to α-aryl substituted γ-ketophosphonates: Lewis acid mediated reactions of 1,3-diketones with α-hydroxyphosphonates and tandem regioselective C–C bond cleavage". Org. Biomol. Chem. 12, № 36 (2014): 7140–49. http://dx.doi.org/10.1039/c4ob01091d.

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Rádai, Zita, Nóra Zsuzsa Kiss, Zoltán Mucsi та György Keglevich. "Synthesis of α-hydroxyphosphonates and α-aminophosphonates". Phosphorus, Sulfur, and Silicon and the Related Elements 191, № 11-12 (2016): 1564–65. http://dx.doi.org/10.1080/10426507.2016.1213261.

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Kabachnik, M. M., L. I. Minaeva та I. P. Beletskaya. "Catalytic synthesis of α-hydroxyphosphonates". Russian Journal of Organic Chemistry 45, № 8 (2009): 1119–22. http://dx.doi.org/10.1134/s1070428009080016.

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Rádai, Zita, Tímea Windt, Veronika Nagy та ін. "Synthesis and anticancer cytotoxicity with structural context of an α-hydroxyphosphonate based compound library derived from substituted benzaldehydes". New Journal of Chemistry 43, № 35 (2019): 14028–35. http://dx.doi.org/10.1039/c9nj02144b.

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We synthesized substituted benzaldehyde derived α-hydroxyphosphonates (αOHP), α-hydroxyphosphonic acids (αOHPA) and α-phosphinoyloxyphosphonates (αOPP) and characterized their cytotoxicity against a panel of cancer cell lines.
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Vamisetti, Ganga B., Raghunath Chowdhury та Sunil K. Ghosh. "Organocatalytic decarboxylative aldol reaction of β-ketoacids with α-ketophosphonates en route to the enantioselective synthesis of tertiary α-hydroxyphosphonates". Organic & Biomolecular Chemistry 15, № 18 (2017): 3869–73. http://dx.doi.org/10.1039/c7ob00796e.

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Sobhani, Sara, та Zahra Tashrifi. "Synthesis of α-functionalized phosphonates from α-hydroxyphosphonates". Tetrahedron 66, № 7 (2010): 1429–39. http://dx.doi.org/10.1016/j.tet.2009.11.081.

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Rádai, Zita, та György Keglevich. "Synthesis and Reactions of α-Hydroxyphosphonates". Molecules 23, № 6 (2018): 1493. http://dx.doi.org/10.3390/molecules23061493.

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Dissertations / Theses on the topic "Α-hydroxyphosphonates"

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Baccari, Zayed [Verfasser]. "Synthèse, propriétés complexantes et activités biologiques de nouveaux α-aminophosphonates et α-hydroxyphosphonates / Zayed Baccari". München : GRIN Verlag, 2019. http://d-nb.info/1180623762/34.

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Book chapters on the topic "Α-hydroxyphosphonates"

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Spilling, Christopher D., and Raj K. Malla. "Synthesis of Non-racemic α-Hydroxyphosphonates via Asymmetric Phospho‐Aldol Reaction." In Phosphorus Chemistry II. Springer International Publishing, 2014. http://dx.doi.org/10.1007/128_2014_583.

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"5. Synthesis of α-hydroxyphosphonates, an important class of bioactive compounds." In Organophosphorus Chemistry. De Gruyter, 2018. http://dx.doi.org/10.1515/9783110535839-005.

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Conference papers on the topic "Α-hydroxyphosphonates"

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Bouzina, Abdeslem, Yousra Ouafa Bouone, Rachida Mansouri та Nour-Eddine Aouf. "Microwave-Assisted BiCl3 Catalyzed Synthesis of α-Hydroxyphosphonates". У ECSOC 2023. MDPI, 2023. http://dx.doi.org/10.3390/ecsoc-27-16282.

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Shaik, Mahammad Sadik, Venkata Narasimha Reddy Kuduthuri, Anil Kumar Kusetty, Pavan Kumar Banaganipalli та Lakshmi Silpa Kandukuri. "Green synthesis of α-hydroxyphosphonates and assessment of their α-amylase activity in vitro". У THE 6TH INTERNATIONAL CONFERENCE OF ICE-ELINVO 2023: Digital Solutions for Sustainable and Green Development. AIP Publishing, 2025. https://doi.org/10.1063/5.0248022.

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Králíková, Šárka, Miloš Buděšínský, Ivana Kavenová та Ivan Rosenberg. "α-Hydroxyphosphonate oligonucleotides: A striking DNA type?" У XIIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2002. http://dx.doi.org/10.1135/css200205356.

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Králíková, Šárka, Miloš Buděšínský, Milena Masojídková, Ivana Kavenová та Ivan Rosenberg. "Synthesis of α-hydroxyphosphonate analogs of ApA and UV spectroscopy study on their complexes with poly(U)". У XIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199902089.

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Králíková, Šárka, Miloš Buděšínský, Radek Liboska, Ondřej Páv та Ivan Rosenberg. "2',5'-Linked oligo-3'-deoxynucleotide chimeras with chiral α-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA?" У XIIIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2005. http://dx.doi.org/10.1135/css200507421.

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