Academic literature on the topic 'Α-solanidine'

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Journal articles on the topic "Α-solanidine"

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Ostrikova, T. O., N. G. Bogomolov, P. Yu Mylnikov, A. V. Shchulkin та I. V. Chernykh. "Development and validation of methods for quantitative determination of α-solanine, α-chaconine, solanidine in extracts from potato tuber peels BY High-performance liquid chromatography–tandem mass spectrometry". Pharmacy & Pharmacology 12, № 2 (2024): 117–30. https://doi.org/10.19163/2307-9266-2024-12-2-117-130.

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Promising metabolites of potato tuberosum (Solanum tuberosum L., f. Solanaceae) are α-solanine, α-chaconine and their aglycone solanidine.The aim of the work was to develop and validate methods for a quantitative analysis of α-solanine, α-chaconine and solanidine in dry extracts from the potato tuber peels by a high-performance liquid chromatography with a tandem mass-selective detection (HPLC/MS/MS).Materials and methods. The analysis was performed in a gradient mode on an Ultimate 3000 chromatograph (ThermoFisher, USA) with a TSQ Fortis tandem mass-selective detector and a 4.6 mm×100 mm, 5 μ
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Punegov, Vasily Vitalievich, Ivan Vladimirovich Gruzdev, Sergey Aleksadrovich Patov, Olga Valerievna Skrotskaya, and Konstantin Vithalievich Chucha. "QUANTITATIVE DETERMINATION OF GLYCOALKALOIDS IN POTATO TUBERS OF VARIETIES "KREPYSH" AND "ROZARA" WHEN CULTIVATED IN THE CONDITIONS OF THE MIDDLE TAIGA SUBZONE OF THE REPUBLIC OF KOMI." chemistry of plant raw material, no. 2 (June 17, 2024): 302–9. https://doi.org/10.14258/jcprm.20240213158.

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The aim of the work was the quantitative determination of glycoalkaloids (GLA) in two varieties of potatoes - Krepysh and Rosara after long-term storage of the crop. It was planned to solve the following tasks: to extract the amount of GLA from samples of potato tubers of the indicated varieties, to determine the presence of GLA in the extract with the identification of solanidine aglycone, to perform a quantitative analysis of the mass fraction of α-chaconine and α-solanine in raw plant material by HPLC analysis. Hydrolytic extraction was used to isolate the GLA fraction of potato varieties K
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Ostrikova, Tatyana Olegovna, Nikita Gennadievich Bogomolov, Aleksey Vladimirovich Shchulkin, Pavel Yuryevich Mylnikov, and Ivan Vladimirovich Chernykh. "DEVELOPMENT OF A TECHNIQUE FOR LIQUID EXTRACTION OF THE AMOUNT OF GLYCOALKALOIDS FROM THE PEEL OF TUBEROUS POTATO TUBERS (SOLANUM TUBEROSUM, F. SOLANACEAE)." chemistry of plant raw material, no. 1 (March 9, 2025): 254–65. https://doi.org/10.14258/jcprm.20250115267.

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Glycoalkaloids (HA) of plants of the Solanaceae family (in particular tuberous potatoes) such as α-solanine and α-chaconin have a wide range of pharmacological effects: antimicrobial, antifungal, antitumor, etc., as demonstrated by the use of individual substances and on various extracts. The use of substances of these substances in practice as medicines has little prospect due to the high cost and foreign production. In this regard, the aim of the work was to develop an economical method for extracting the amount of HA from the standardized peel of tuberous potato tubers to obtain a dry extra
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Dahlin, Paul, Marion C. Müller, Sophia Ekengren, Lauren S. McKee, and Vincent Bulone. "The Impact of Steroidal Glycoalkaloids on the Physiology of Phytophthora infestans, the Causative Agent of Potato Late Blight." Molecular Plant-Microbe Interactions® 30, no. 7 (2017): 531–42. http://dx.doi.org/10.1094/mpmi-09-16-0186-r.

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Steroidal glycoalkaloids (SGAs) are plant secondary metabolites known to be toxic to animals and humans and that have putative roles in defense against pests. The proposed mechanisms of SGA toxicity are sterol-mediated disruption of membranes and inhibition of cholinesterase activity in neurons. It has been suggested that phytopathogenic microorganisms can overcome SGA toxicity by enzymatic deglycosylation of SGAs. Here, we have explored SGA-mediated toxicity toward the invasive oomycete Phytophthora infestans, the causative agent of the late blight disease in potato and tomato, as well as the
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Nielsen, Søren D., Jesper M. Schmidt, Gitte H. Kristiansen, Trine K. Dalsgaard та Lotte B. Larsen. "Liquid Chromatography Mass Spectrometry Quantification of α-solanine, α-chaconine, and Solanidine in Potato Protein Isolates". Foods 9, № 4 (2020): 416. http://dx.doi.org/10.3390/foods9040416.

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For potato proteins to be used as a food ingredient, the level of natural potato defense substances, the glycoalkaloids (GAs), should be limited. In this work, a method is developed for quantification of the two major potato GAs, α-solanine and α-chaconine, as well as for their aglycon form, solanidine, using liquid chromatography–mass spectrometry single quadrupole in single ion monitoring mode. Standard solutions of GA and a food-grade potato protein powder was used to validate the method. A linear correlation between GA concentration and the ion intensity of >0.995 was obtained for all s
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Okada, Kohki, та Kano Matsuo. "Development of New Antibodies and an ELISA System to Detect the Potato Alkaloids α-Solanine and α-Chaconine". Foods 12, № 8 (2023): 1621. http://dx.doi.org/10.3390/foods12081621.

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Food poisoning can be caused by the potato alkaloids α-solanine (SO) and α-chaconine (CHA). Therefore, this study aimed to establish new enzyme-linked immunosorbent assays (ELISAs) for detecting these two toxins in biological samples and potato extracts. Two antibodies that bind to solanidine, a chemical compound found in both SO and CHA, were newly developed, and two types of ELISAs (Sold1 ELISA and Sold2 ELISA) were constructed. We measured SO and CHA diluted in phosphate-buffered saline (PBS), serum, and urine. The detection performance of the two ELISAs for SO and CHA in PBS was higher tha
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Friedman, Mendel, та P. R. Henika. "Absence of genotoxicity of potato alkaloids α-chaconine, α-solanine and solanidine in the ames salmonella and adult and foetal erythrocyte micronucleus assays". Food and Chemical Toxicology 30, № 8 (1992): 689–94. http://dx.doi.org/10.1016/0278-6915(92)90164-g.

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Kalydi, Eszter, Nikoletta Murvai, Emmanuel Saridakis та ін. "Molecular encapsulation of the aminosteroid phytotoxins solanidine and α-solanine by sugammadex: new insights into atomic-level interactions". Carbohydrate Polymers 366 (жовтень 2025): 123824. https://doi.org/10.1016/j.carbpol.2025.123824.

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Sodipo, O.A., F. I. Abdulrahman, U.K. Sandabe та B. Wampana. "Comparative Assessment of the Total Lipid Profile, Faecal Cholesterol, Very Low Density Lipoprotein Cholesterol (VLDL-C) and Altherogenic Index (A.I.) of the Aqueous Fruit Extract of Solanum macrocarpum, α-solanidine and Antihyperlipidaemic Drugs on Triton-Induced Hyperlipdaemic Rats". Greener Journal of Medical Sciences 3, № 1 (2013): 8–17. https://doi.org/10.15580/gjms.2013.1.120212312.

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Studies were undertaken on the effect of 50mg/kg each of the aqueous fruit extract of Solanum macrocarpum, α-solanidine, (a steroidal glycoalkaloid found in the Solanaceae), three antihyperlipidaemic drugs namely nicotinic acid, simvastatin and cholestyramine) on forty two (42) rats made hyperlipidaemic by treating them with 400 mg/kg triton-X for 7 days. The rats were divided into 7 groups of 6 rats each. At 24hrs, 48hrs and 72hrs respectively, the rats in each group were humanely sacrificed and blood samples collected for analysis of total lipid profile [total cholesterol, triglyceride
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ZHANG, Xiuyao, Xinxin CAI та Xiaoyi ZHANG. "Determination ofα-solanine,α-chaconine and solanidine in plasma and urine by ultra-performance liquid chromatography-triple quadrupole mass spectrometry". Chinese Journal of Chromatography 32, № 6 (2014): 586. http://dx.doi.org/10.3724/sp.j.1123.2014.03001.

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Dissertations / Theses on the topic "Α-solanidine"

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Koffi, Grokore yvonne. "CARACTERISATION DE LA B-GLYCOSIDASE DE LA BLATTE PERIPLANETA AMERICANA : APPLICATION A LA VALORISATION DES GLYCOALCALOÏDES DE LA POMME DE TERRE EN DECOMPOSITION." Thesis, Toulouse, INSA, 2016. http://www.theses.fr/2016ISAT0040/document.

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La pomme de terre produit des glycoalcaloïdes comme la plupart des Solanacées. Deux composés, en particulier, l’α-solanine et l’α-chaconine, sont produits en plus grande quantité lorsque le tubercule est exposé à la lumière et subit des dégradations. Ces molécules sont toxiques et peuvent représenter un danger pour le consommateur et des nuisances pour l’environnement. Dans le cadre de cette thèse, les teneurs en α-solanine et α-chaconine dans la chaire de pomme de terre verdie, en germination ou en décomposition retrouvées sur les marchés d’Abidjan (Côte d'Ivoire) ont été analysées. Les résul
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