Relevant bibliographies by topics / ΑVβ6 integrin

Contents

  1. Dissertations / Theses

Academic literature on the topic 'ΑVβ6 integrin'

Author: Grafiati
Published: 22 February 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'ΑVβ6 integrin.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Dissertations / Theses on the topic "ΑVβ6 integrin"

1

Marsh, D. J. "The αvβ6 integrin in cancer". Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1331896/.

Full text
Abstract:
The epithelial restricted αvβ6 integrin is known to have minimal expression in healthy tissue and to be upregulated in cancer and healing wounds. This thesis explores the role of αvβ6 in cancer and tests the hypothesis that αvβ6 has a prognostic and therapeutic utility in cancer. Using immunohistochemistry, increased αvβ6 expression was found in nonmelanoma skin cancers (NMSC), particularly in morphoeic type basal cell carcinoma. In cell culture experiments, αvβ6 was found to activate TGF-β and promote myofibroblast differentiation, producing a tumour stroma rich in smooth muscle actin (SMA).
APA, Harvard, Vancouver, ISO, and other styles
2

Vallath, Sabarinath S. "Studying the role of integrin αVβ6 in pancreatic cancer". Thesis, Queen Mary, University of London, 2013. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8663.

Full text
Abstract:
Pancreatic cancer is often referred to as the “silent killer“ due to the asymptomatic nature of the disease in the early stages and the extremely poor prognosis overall. The average one-year survival rate for PDAC patients is 24% (American Cancer Society, facts and figures, 2010), decreasing to 5%-6% over 5 years (WHO report, Pancreatic cancer, 2010). Only 20% of patients are suitable for surgical resection at the time of diagnosis and treatment options available to PDAC patients have not improved significantly over the past few decades. Thus novel therapeutic approaches are essential to treat
APA, Harvard, Vancouver, ISO, and other styles
3

Hayward, Mary-Kate. "Mechanostimulation of integrin αvβ6 and fibronectin in DCIS myoepithelial cells". Thesis, Queen Mary, University of London, 2018. http://qmro.qmul.ac.uk/xmlui/handle/123456789/54057.

Full text
Abstract:
Alterations to the tumour microenvironment is a common feature of many cancers, including breast cancer, and there is increasing evidence that alterations to the microenvironment, including; increased integrin expression, ECM deposition and protease activity, promote cancer progression. Most invasive breast cancers arise from a preinvasive stage, ductal carcinoma in situ (DCIS). Previous work in our laboratory has shown the microenvironment of DCIS is altered, such that myoepithelial cells (MECs) switch to a tumour-promoting phenotype, associated with upregulation of integrin αvβ6 and fibronec
APA, Harvard, Vancouver, ISO, and other styles
4

Ylipalosaari, M. (Merja). "Matrix metalloproteinases (MMPs) in oral carcinomas." Doctoral thesis, University of Oulu, 2005. http://urn.fi/urn:isbn:9514277309.

Full text
Abstract:
Abstract Matrix metalloproteinases, MMPs, are a family of enzymes capable of modulating connective tissue components. The expression of several MMPs is increased in oral squamous cell carcinomas (OSCCs). They are assumed to have an important role in the development and progression of OSCCs. However, the exact role and mechanism of the regulation of MMPs in malignant transformation are still largely unknown. In this study, tumour-associated trypsin-2 (TAT-2) was detected in OSCC tissue sections, and its role in MMP-2 and -9 regulation in carcinoma cells was evaluated. The TAT-2 gene was trans
APA, Harvard, Vancouver, ISO, and other styles
5

Dirheimer, Luca. "Ciblage de modèles cellulaires 3D par des agents de contrastes fluoresçant dans le proche infrarouge : application à la chirurgie guidée par la fluorescence des cancers de la tête et du cou." Electronic Thesis or Diss., Université de Lorraine, 2024. http://www.theses.fr/2024LORR0159.

Full text
Abstract:
La résection chirurgicale constitue le traitement de première intention des cancers de la tête et du cou (HNSCC). La berge peropératoire est un facteur de pronostic majeur pour la survie globale des patients. Actuellement, il existe peu d’outils pour discriminer de manière fiable et en temps réel le tissu tumoral du tissu sain. La chirurgie guidée par la fluorescence (FGS) proche infrarouge (NIR) est une méthode d’imagerie utilisant le marquage fluorescent des tissus tumoraux afin de fournir une image de contraste augmentée. Le but de ces travaux est l’étude de la distribution de Quantum Dots
APA, Harvard, Vancouver, ISO, and other styles
6

Nieberler, Markus [Verfasser], Klaus-Dietrich Akademischer Betreuer] Wolff, Andreas [Akademischer Betreuer] Kolk та Henning [Akademischer Betreuer] [Bier. "Entwicklung und klinische Etablierung einer intraoperativen zytologischen Diagnostik der Knocheninfiltration bei Kopf-Hals-Karzinomen mit Charakterisierung von αvβ6 Integrin als Biomarker invasiver Karzinomzellen / Markus Peter Nieberler. Gutachter: Klaus-Dietrich Wolff ; Andreas Kolk ; Henning August Bier. Betreuer: Klaus-Dietrich Wolff". München : Universitätsbibliothek der TU München, 2014. http://d-nb.info/1058214454/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Mathias, Lucas Solla. "Ativação da via MAPK/ERK e Integrina αvβ3 pela ação da triiodotironina (T3) na modulação da expressão gênica de adipocinas e modificação do perfil lipídico em adipócitos, 3T3-L1". Botucatu, 2019. http://hdl.handle.net/11449/181721.

Full text
Abstract:
Orientador: Miriane de Oliveira<br>Resumo: Introdução: O hormônio triiodotironina (T3) influencia o metabolismo e desenvolvimento do tecido adiposo (TA), modulando a proliferação e diferenciação de adipócitos, podendo agir sobre os reguladores do processo de adipogênese, como o receptor ativado por proliferador de peroxissomo (PPARy). O TA está envolvido na regulação da energia corporal, sintetizando e secretando substâncias denominadas adipocinas, dentre elas a adiponectina e leptina. A adiponectina está relacionada ao aumento da sensibilidade à insulina, enquanto a leptina está envol
APA, Harvard, Vancouver, ISO, and other styles
8

Elsharif, Amal A. M. "Functional Investigation of Dual αvβ3 and αllbβ3 Integrin Inhibition in Haematological and Solid Tumour Models". Thesis, University of Bradford, 2018. http://hdl.handle.net/10454/16883.

Full text
Abstract:
Invasion and metastasis of cancer is the leading cause of increased mortality. In addition, haematological malignancies (leukaemia and lymphoma) are a significant cause of morbidity and mortality in both children and adults. Therefore, new treatments which will inhibit cancer progression are required. Integrin adhesion receptors, particularly the RGD-binding integrin subfamily comprising αvβ3, αvβ5, αvβ6, αvβ8, αllbβ3, α5β1, α8β1 and αvβ1 are related to progress and spread of cancer and poor prognosis. Because of the importance of integrin biology in the regulation of cancer dissemination, the
APA, Harvard, Vancouver, ISO, and other styles
9

Ahmedah, Hanadi Talal A. "Correlation between the expression of integrins and their role in cancer progression : expression pattern of integrins αvβ3, αvβ5 and α5β1 in clinical and experimental tumour samples". Thesis, University of Bradford, 2015. http://hdl.handle.net/10454/14284.

Full text
Abstract:
The integrins play a crucial role in cancer cell proliferation, migration, differentiation, survival and angiogenesis. It has been shown that integrin expression is positively correlated to cancer dissemination, this suggests targeting selected integrins as an anti-metastatic strategy. The aim of this study is to investigate the effect of novel antagonists of α5β1, αvβ3 and αvβ5 integrins on cancer cell migration, a key process in tumour cell dissemination. Immunohistochemistry was used to evaluate the expression of α5, αv, β3 and β5 integrin subunits in prostate cancer tissues. Furthermore th
APA, Harvard, Vancouver, ISO, and other styles
10

Ahmedah, Hanadi T. A. "Correlation between the expression of integrins and their role in cancer progression. Expression pattern of integrins αvβ3, αvβ5 and α5β1 in clinical and experimental tumour samples". Thesis, University of Bradford, 2015. http://hdl.handle.net/10454/14284.

Full text
Abstract:
The integrins play a crucial role in cancer cell proliferation, migration, differentiation, survival and angiogenesis. It has been shown that integrin expression is positively correlated to cancer dissemination, this suggests targeting selected integrins as an anti-metastatic strategy. The aim of this study is to investigate the effect of novel antagonists of α5β1, αvβ3 and αvβ5 integrins on cancer cell migration, a key process in tumour cell dissemination. Immunohistochemistry was used to evaluate the expression of α5, αv, β3 and β5 integrin subunits in prostate cancer tissues. Further
APA, Harvard, Vancouver, ISO, and other styles
More sources
You might also be interested in the extended bibliographies on the topic 'ΑVβ6 integrin' for particular source types:
Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography