Academic literature on the topic 'Β-aminoketones'

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Journal articles on the topic "Β-aminoketones"

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Fraser, David S., Sheldon B. Park та J. Michael Chong. "Diastereoselective reduction of α-aminoketones: Synthesis of anti- and syn-β-aminoalcohols". Canadian Journal of Chemistry 82, № 2 (2004): 87–101. http://dx.doi.org/10.1139/v03-165.

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Reduction of N-t-BOC-protected-N-alkyl α-aminoketones with LiEt3BH or Li(s-Bu)3BH furnishes protected syn-β-aminoalcohols with high selectivities. In contrast, removal of the BOC group followed by reduction of the aminoketone gives anti-β-aminoalcohols with variable selectivities. With aromatic ketones, selectivities are typically high while aliphatic ketones show mediocre to high selectivities depending on steric considerations.Key words: β-aminoalcohol, diastereoselective reduction.
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2

Deng, Guisheng, Honghua Mo, Jing Luo, and Jingyuan Zou. "Highly diastereoselective Mannich-type reaction of titanium enolate derived from 2′-hydroxypropiophenone." Canadian Journal of Chemistry 90, no. 6 (2012): 542–50. http://dx.doi.org/10.1139/v2012-027.

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Mannich-type addition of the titanium enolate derived from 2′-hydroxypropiophenone to N-tosylimines provided the corresponding β-aminoketones in good to excellent yields (60%–90%) and with >99 : <1 anti diastereoselectivity. A model for synthesis of anti β-aminoketone as a predominant isomer based on the titanium enolate has been developed. High anti selectivity is not independent of the electron-donating and electron-withdrawing groups on the phenyl ring of the N-tosylimines. Noteworthy is the observation that the influence of a second Lewis acid on the Mannich-type reaction based on th
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3

Gevorgyan, G. A., A. G. Agababyan та O. L. Mndzhoyan. "Chemical Reactions of β-Aminoketones". Russian Chemical Reviews 54, № 5 (1985): 495–514. http://dx.doi.org/10.1070/rc1985v054n05abeh003079.

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4

Chandrashaker, Vanampally, Marcin Ptaszek, Masahiko Taniguchi, and Jonathan S. Lindsey. "Synthesis of diverse acyclic precursors to pyrroles for studies of prebiotic routes to tetrapyrrole macrocycles." New Journal of Chemistry 40, no. 10 (2016): 8786–808. http://dx.doi.org/10.1039/c6nj02048h.

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Some 50 ketones, β-diketones, β-ketoesters and α-aminoketones have been prepared for studies of the formation of trisubstituted pyrroles equipped for self-condensation leading to tetrapyrrole macrocycles.
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5

Hammouda, Mohamed M., та Khaled M. Elattar. "Recent progress in the chemistry of β-aminoketones". RSC Advances 12, № 38 (2022): 24681–712. http://dx.doi.org/10.1039/d2ra03864a.

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SanMartín, Raúl, Eduardo Martínez de Marigorta та Esther Domínguez. "A convenient alternative route to β-aminoketones". Tetrahedron 50, № 7 (1994): 2255–64. http://dx.doi.org/10.1016/s0040-4020(01)85083-3.

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Fu, Rui, Yu Liu, Tao Wu та ін. "Metal-free synthesis of β-aminoketones by the reductive hydroamination of ynones". Chemical Communications 58, № 21 (2022): 3525–28. http://dx.doi.org/10.1039/d2cc00169a.

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This paper describes a cascade method for the synthesis of β-aminoketones through the reductive hydroamination of alkynes under metal-free conditions. This process can be applied to synthesis of drug molecules including Proroxan and Propipocaine.
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8

Seebacher, Werner, Michael Hoffelner, Ferdinand Belaj, et al. "Formation of 5-Aminomethyl-2,3-dihydropyridine-4(1H)-ones from 4-Amino-tetrahydropyridinylidene Salts." Molecules 28, no. 19 (2023): 6869. http://dx.doi.org/10.3390/molecules28196869.

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Various 4-aminotetrahydropyridinylidene salts were treated with aldehydes in an alkaline medium. Their conversion to 5-substituted β-hydroxyketones in a one-step reaction succeeded only with an aliphatic aldehyde. Instead, aromatic aldehydes gave 5-substituted β-aminoketones or a single δ-diketone. The new compounds were characterized using spectroscopic methods and a single crystal structure analysis. Some of them showed anticancer and antibacterial properties.
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Muralev, A. E., S. S. Mochalov, U. A. Barbalat та N. P. Kuz’mina. "Synthesis and photoluminescent properties of benzodioxan β-aminoketones". Moscow University Chemistry Bulletin 64, № 4 (2009): 214–18. http://dx.doi.org/10.3103/s0027131409040087.

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Simplício, Ana Luísa, John M. Clancy та John F. Gilmer. "β-Aminoketones as prodrugs with pH-controlled activation". International Journal of Pharmaceutics 336, № 2 (2007): 208–14. http://dx.doi.org/10.1016/j.ijpharm.2006.11.055.

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Book chapters on the topic "Β-aminoketones"

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Singh, Karan. "Heterocyclic Compounds Containing Bifunctional β -Aminoketone Skeleton." In Recent Developments in Chemistry and Biochemistry Research Vol. 1. B P International, 2024. http://dx.doi.org/10.9734/bpi/rdcbr/v1/8913a.

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