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Journal articles on the topic '004.4:519.816 (043.3)'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics

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N., Kamel, Mouheb Y., Kamariz S., Aouchiche F., Moudir D., and Arabi A. "Synthesis and characterization of a Mo-rich aluminoborosilicate glass by a double melt process." European Journal of Advances in Engineering and Technology 6, no. 2 (2019): 17–25. https://doi.org/10.5281/zenodo.10686913.

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<strong>ABSTRACT</strong> A Mo-rich aluminoborosilicate glass dedicated for nuclear waste confinement, containing 0.3 to 0.6 wt.% of Cs, is synthesized by a double melting at 1380°C during 3 h, followed by a 2 h annealing step at 600°C. The glasses density varied randomly with the Cs content from 1.43 to 2.73. The X-ray diffraction phase identification reveals similar features for the glasses with 0.3 and 0.6wt.%, with a minor crystalline phase identified as powellite. For 0.4 wt.% Cs, traces of crystalline phases of monoclinic coesite SiO<sub>2</sub>, iron silicate (Fe<sub>3</sub>Al<s

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Doshi, Chirag, Mazyar Zahir, Anosh Dadabhoy, et al. "Impact of insurance type on outcomes after radical cystectomy for bladder cancer." Journal of Clinical Oncology 43, no. 5_suppl (2025): 679. https://doi.org/10.1200/jco.2025.43.5_suppl.679.

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679 Background: A patient’s insurance status can significantly impact their access to care, potentially altering their treatment course and outcomes. This study aimed to evaluate the potential influence of different insurance statuses on oncological outcomes, including survival. Methods: We utilized our prospectively maintained IRB-approved radical cystectomy (RC) database (#HS-01B014) to identify all muscle invasive bladder cancer (MIBC) patients who underwent neoadjuvant chemotherapy (NAC) followed by RC from 2000 to 2023. Patients were then categorized based on primary insurance type to Pre

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Dörner, T., Y. Tanaka, M. Mosca, et al. "POS0714 POOLED SAFETY ANALYSIS OF BARICITINIB IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM THREE RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, CLINICAL TRIALS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 639.1–639. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2375.

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BackgroundBaricitinib (BARI), an oral selective inhibitor of Janus kinase 1 and 2 approved for the treatment of rheumatoid arthritis and atopic dermatitis, has been evaluated in clinical studies in patients with systemic lupus erythematosus (SLE).ObjectivesTo assess the safety profile of BARI in patients with SLE.MethodsPatients with SLE receiving stable background therapy were randomised 1:1:1 to BARI 2-mg, 4-mg, or placebo (PBO) once daily in one 24-week, phase 2 (NCT02708095) and two 52-week, phase 3, PBO controlled studies (NCT03616912 and NCT03616964).ResultsA total of 1,849 patients were

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Khare, Reeti, Tarush Kothari, Joseph Castagnaro, Bryan Hemmings, May Tso, and Stefan Juretschko. "Active Monitoring and Feedback to Improve Blood Culture Fill Volumes and Positivity Across a Large Integrated Health System." Clinical Infectious Diseases 70, no. 2 (2019): 262–68. http://dx.doi.org/10.1093/cid/ciz198.

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AbstractBackgroundThe sensitivity of blood cultures increases with the volume of blood collected. However, hospitals face challenges in collecting adequate volume, and underfilled blood bottles are ubiquitous.MethodsBlood bottle fill volumes were measured using an automated monitoring system across multiples sites (10 hospitals, 3 laboratories) within a large suburban/urban health system. Baseline fill volumes were measured for 4 months. A quality improvement program was then implemented over 36 months. Strategies to improve fill volumes included education, standardized data collection, novel

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Cairo, Mitchell S., Erin Cooney, Mark Krailo, et al. "A Phase I Study of 90Y-Ibritumomab-Tiuxetan (90Y-It) in Children with Recurrent/Refractory CD20 Positive Lymphoma: A Cog Phase I Consortium Study." Blood 106, no. 11 (2005): 2448. http://dx.doi.org/10.1182/blood.v106.11.2448.2448.

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Abstract More than 98% of newly diagnosed childhood B-NHL expresses CD20 (Perkins/Cairo, Clin Adv Hem/Onc 2003). The prognosis for children and adolescents with recurrent CD20 positive NHL, particularly DLBCL and BL, is dismal (Cairo et al, Am J Hem, 2003, Cairo et al, Br J Hem, 2003). A radiolabeled anti-CD20 antibody, 90Y-IT, has recently received FDA approval for adults with recurrent indolent CD20+ B-NHL. The dose limiting toxicity in adults has been myelosuppression (Witzig et al, JCO, 2003). Through the COG Phase I Consortium, we evaluated the safety of 90Y-IT in Pts with refractory chil

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De Agustin, J. J., G. Añez, D. Reina-Sanz, et al. "AB1116 APREMILAST IN PSORIATIC ARTHRITIS. ULTRASOUND ANALYSIS (JOINT-ENTHESES-UNGUEAL INDEX) OF THE EFFICACY AND VARIABLES CORRELATION STUDY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1787–88. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1397.

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BackgroundWe conducted a study using ultrasonography (US) to evidence inflammatory changes (joint-enthesis-ungueal) in active PsA (aPsA) patients who started Apremilast (A) in clinical practice.ObjectivesObtain a 20, 50, 70 % reduction in the US index (UIC) at 12 months, and study correlation between variables.MethodsPhase IV, multicenter, prospective and open-label clinical trialconductedin 9 centresfrom 2018 to 2021. All patients signed the informed consent. Approval by the ethical committee was obtained, code PSA-PI-006421. PsA patients (≥ 2 swollen joints), ≥ 2 joint US synovitis and ≥ 1 U

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Taparra, Kekoa, Vera Qu, and Erqi Pollom. "Disparities in Survival and Comorbidity Burden Between Asian and Native Hawaiian and Other Pacific Islander Patients With Cancer." JAMA Network Open 5, no. 8 (2022): e2226327. http://dx.doi.org/10.1001/jamanetworkopen.2022.26327.

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ImportanceImproper aggregation of Native Hawaiian and other Pacific Islander individuals with Asian individuals can mask Native Hawaiian and other Pacific Islander patient outcomes. A comprehensive assessment of cancer disparities comparing Asian with Native Hawaiian and other Pacific Islander populations is lacking.ObjectiveTo compare comorbidity burden and survival among East Asian, Native Hawaiian and other Pacific Islander, South Asian, and Southeast Asian individuals with non-Hispanic White individuals with cancer.Design, Setting, and ParticipantsThis retrospective cohort study used a nat

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Steinkamp, Gratiana, Hans Demmelmair, Ina Rühl‐Bagheri, Horst von der Hardt, and Berthold Koletzko. "Energy Supplements Rich in Linoleic Acid Improve Body Weight and Essential Fatty Acid Status of Cystic Fibrosis Patients." Journal of Pediatric Gastroenterology and Nutrition 31, no. 4 (2000): 418–23. http://dx.doi.org/10.1002/j.1536-4801.2000.tb07150.x.

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ABSTRACTBackgroundPatients with cystic fibrosis who have steatorrhea frequently are underweight and have essential fatty acid (EFA) depletion, which is associated with a poor clinical course. It has been stated that poor EFA status is difficult to correct in patients with cystic fibrosis, and an impaired EFA metabolism with reduced synthesis of long‐chain polyunsaturated fatty acids has been proposed. In this study, the effects of an oral energy supplement rich in linoleic acid were investigated in patients with cystic fibrosis who had a body weight below 95% of normal for height.MethodsThirty

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Sakhin, V., M. Grigoriev, O. Rukavitsyn, E. Kryukov, and S. Kazakov. "SAT0089 FEATURES OF THE SECRETION OF INTERLEUKIN-6, INTERLEUKIN-10, TUMOR NECROSIS FACTOR ALPHA IN PATIENTS WITH RHEUMATOID ARTHRITIS ASSOCIATED WITH ANEMIA." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 978.1–979. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1264.

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Background:Anemia is widespread in rheumatic patients and is an important extra-articular manifestation that correlates with physical disability and increased mortality. The pathogenesis of such anemia is complex and multifactorial, including due to the influence of pro-inflammatory cytokines.Objectives:Our aim was to study the characteristics of the secretion of interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-alpha (TNF-α) in patients with rheumatoid arthritis (RA) with anemia of chronic diseases (ACD), iron deficiency anemia (IDA) and a combination of ACD / IDA, as well a

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Schwellnus, Martin, Charl Janse van Rensburg, Helen Bayne, et al. "Team illness prevention strategy (TIPS) is associated with a 59% reduction in acute illness during the Super Rugby tournament: a control–intervention study over 7 seasons involving 126 850 player days." British Journal of Sports Medicine 54, no. 4 (2019): 245–49. http://dx.doi.org/10.1136/bjsports-2019-100775.

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ObjectivesTo determine whether a team illness prevention strategy (TIPS) would reduce the incidence of acute illness during the Super Rugby tournament.MethodsWe studied 1340 male professional rugby union player seasons from six South African teams that participated in the Super Rugby tournament (2010–2016). Medical staff recorded all illnesses daily (126 850 player days) in a 3-year control (C: 2010–2012; 47 553 player days) and a 4-year intervention (I: 2013–2016; 79 297 player days) period. A five-element TIPS was implemented in the I period, following agreement by consensus. Incidence rate

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Fomin, I. V., and N. G. Vinogradova. "Rationale of specialized medical care for patients with chronic heart failure in the Russian Federation." South Russian Journal of Therapeutic Practice 1, no. 3 (2020): 44–53. http://dx.doi.org/10.21886/2712-8156-2020-1-3-44-53.

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Objectives: to determine the causes of ineffective observation and poor prognosis in patients undergoing ADHF, in real clinical practice and to consider the basics of the formation of specialized medical care for patients with heart failure (HF).Materials and methods: the study was conducted based on the City Center for the treatment of heart failure (center HF), N. Novgorod. The study consistently included 942 patients with heart failure (HF) at the age of 18 years and older who underwent ADHF and received inpatient treatment in center HF between March 4, 2016 and March 3, 2017. Based on the

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Rhee, Chanu, Tom Chen, Sameer S. Kadri, et al. "Trends in Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals." JAMA Network Open 7, no. 6 (2024): e2418923. http://dx.doi.org/10.1001/jamanetworkopen.2024.18923.

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ImportanceLittle is known about the degree to which suspected sepsis drives broad-spectrum antibiotic use in hospitals, what proportion of antibiotic courses are unnecessarily broad in retrospect, and whether these patterns are changing over time.ObjectiveTo describe trends in empiric broad-spectrum antibiotic use for suspected community-onset sepsis.Design, Setting, and ParticipantsThis cross-sectional study used clinical data from adults admitted to 241 US hospitals in the PINC AI Healthcare Database. Eligible participants were aged 18 years or more and were admitted between 2017 and 2021 wi

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Longenecker, Christopher T., Kelley A. Jones, Corrilynn O. Hileman, et al. "Nurse-Led Strategy to Improve Blood Pressure and Cholesterol Level Among People With HIV." JAMA Network Open 7, no. 3 (2024): e2356445. http://dx.doi.org/10.1001/jamanetworkopen.2023.56445.

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ImportanceDespite higher atherosclerotic cardiovascular disease (ASCVD) risk, people with HIV (PWH) experience unique barriers to ASCVD prevention, such as changing models of HIV primary care.ObjectiveTo test whether a multicomponent nurse-led strategy would improve systolic blood pressure (SBP) and non–high-density lipoprotein (HDL) cholesterol level in a diverse population of PWH receiving antiretroviral therapy (ART).Design, Setting, and ParticipantsThis randomized clinical trial enrolled PWH at 3 academic HIV clinics in the US from September 2019 to January 2022 and conducted follow-up for

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Oztas, M., M. Bektaş, I. Karacan, et al. "AB1082 FREQUENCY AND SEVERITY OF COVID-19 IN PATIENTS WITH VARIOUS RHEUMATIC DISEASES TREATED REGULARLY WITH COLCHICINE OR HYDROXYCHLOROQUINE." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1660.2–1661. http://dx.doi.org/10.1136/annrheumdis-2022-eular.83.

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BackgroundSeveral anti-inflammatory drugs which were targeted different mechanisms and investigated for both prevention and treatment for COVID-19.ObjectivesThe current study aimed to investigate whether patients regularly using colchicine or hydroxychloroquine (HCQ) have an advantage of protection from COVID-19 or developing less severe disease.MethodsPatients who were taking colchicine or HCQ regularly for a rheumatic disease including Familial Mediterranean Fever, Behçet’s syndrome, Systemic Lupus Erythematosus, Rheumatoid Arthritis and Sjogren’s syndrome as well as their healthy household

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Banerjee, Rahul, Ken Hasegawa, Taha Itani, et al. "Health Related Quality of Life (HRQoL) in Relapsed/Refractory Multiple Myeloma (RRMM): A Systematic Literature Review (SLR) and Meta-Analysis." Blood 144, Supplement 1 (2024): 4721. https://doi.org/10.1182/blood-2024-203741.

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Background: While narrative SLRs of HRQoL in RRMM have been conducted recently (Ojo et al, 2024), these have not accounted for the recent rise of cellular therapies. The objective of this study was to provide specific baseline EORTC QLQ-C30 or QLQ-MY20 scores for use as benchmarks in future research. Methods: MEDLINE, EMBASE, CENTRAL and pertinent conferences were systematically searched for publications (January 2012 to March 2024) of clinical trials or observational real-world evidence (RWE) studies of patients with RRMM in the context of any pharmacological intervention. To generate benchma

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Volkmann, E., Z. Mcmahan, S. Johnson, et al. "POS0840 RISK OF MALNUTRITION IN PATIENTS WITH SYSTEMIC SCLEROSIS-ASSOCIATED INTERSTITIAL LUNG DISEASE (SSC-ILD): FURTHER ANALYSES OF THE SENSCIS TRIAL." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 674.1–674. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1083.

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Background:Gastrointestinal (GI) involvement is common in patients with SSc and may lead to weight loss and malnutrition. In the SENSCIS trial in patients with SSc-ILD, nintedanib reduced the rate of decline in forced vital capacity (FVC) (mL/year) over 52 weeks, with mainly GI adverse events. The Malnutrition Universal Screening Tool (MUST) was developed to identify adults who are at risk of malnutrition and has been used in studies of patients with SSc.Objectives:To evaluate nutritional status over 52 weeks in the SENSCIS trial based on a modified MUST score.Methods:The SENSCIS trial enrolle

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Magnus, Dan, Santosh Bhatta, and Julie Mytton. "432 Establishing injury surveillance in emergency departments in Nepal: epidemiology and burden of paediatric injuries." Emergency Medicine Journal 37, no. 12 (2020): 825.2–827. http://dx.doi.org/10.1136/emj-2020-rcemabstracts.7.

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Aims/Objectives/BackgroundGlobally, injuries cause more than 5 million deaths annually. Children and young people are a particularly vulnerable group and injuries are the leading cause of death in people aged 5–24 years globally and a leading cause of disability.In most low and middle-income countries where the majority of global child injury burden occurs, systems for routinely collecting injury data are limited. There is a continuing need for better data on childhood injuries and for injury surveillance.The aim of our study was to introduce a hospital-based injury surveillance tool – the fir

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Ben Nessib, D., M. Yasmine, H. Ferjani, et al. "AB0768 Influence of continuous non-steroidal anti-inflammatory drugs intake on bone marrow edema in non-radiographic Spondyloarthritis." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1510.2–1510. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3103.

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BackgroundThe concept of non-radiographic axial spondyloarthritis (nr-axSpA) has revolutionized the classical understanding of axSpA. Indeed, it facilitated the classification of patients with axSpA who did not present substantial structural damage as it was only detectable on magnetic resonance imaging of the sacroiliac joints (MRI-SIJ) [1]. Continuous non-steroidal anti-inflammatory (NSAIDs) intake has been reported as a potential factor reducing the sensitivity of MRI-SIJ to detect bone marrow edema (BME).ObjectivesThe aim of the study was to investigate the effect of continuous NSAIDs inta

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Biller, Beverly M. K., Maria Fleseriu, Rosario Pivonello, et al. "PMON160 Improvements in Clinical Signs of Hypercortisolism and Quality of Life According to Urinary and Late-Night Salivary Cortisol Levels in Patients with Cushing's Disease Treated with Osilodrostat." Journal of the Endocrine Society 6, Supplement_1 (2022): A545. http://dx.doi.org/10.1210/jendso/bvac150.1133.

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Abstract Objective Cushing's disease (CD) is a debilitating disorder of chronic hypercortisolism. Assessment of 24h mean urinary free cortisol (mUFC) and late-night salivary cortisol (LNSC) is recommended for screening and monitoring treatment response. In the published core period of the Phase III, LINC 3 study (NCT02180217), osilodrostat therapy (a potent oral 11β-hydroxylase inhibitor) produced rapid, sustained reductions in both mUFC and LNSC alongside improvements in clinical signs of hypercortisolism and health-related quality of life (HRQoL) in patients with CD. Here we explored cardiov

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Olivia, Bass, and Koevary* Steven. "Uveal Melanoma: an Updated Review." Biomedical Research and Reviews (ISSN:2631-3944) 2, no. 2 (2019): 1–10. https://doi.org/10.5281/zenodo.7943557.

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<strong>Abstract</strong> This article reviews the epidemiology, pathophysiology, and treatment of uveal melanoma. Emphasis is placed on differential diagnosis and the genetics associated with tumor development and metastasis. The role of the <em>BRCA1</em>-associated protein 1 <em>(BAP1)</em> gene, a suggested uveal melanoma tumor suppressor gene, <em>EIF1AX</em>, a gene that encodes a protein that binds mRNA, among other genes, as well as the associated loss of chromosome 3 are discussed. While the treatment of primary uveal melanoma is generally successful, up to approximately 50% of patien

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Avilov, Sviatoslav V., Larisa A. Bityutskaya та Evelina P. Domashevskaya. "Топологическая модель структуры и нелинейная модель формирования тетраподов ZnO". Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 21, № 4 (2019): 458–70. http://dx.doi.org/10.17308/kcmf.2019.21/2357.

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В работе предложена модель формирования морфологии тетраподов ZnO,основанная на описании процесса полиморфного перехода от октаэдрических кластеровс кристаллической структурой сфалерита B3 к четырем стрежневым кристаллам со струк-турой вюрцита B4 как разрыва топологического пространства роста на наномасштабе. Примоделировании предкристаллизационного этапа формирования тетраподов в условияхдинамического хаоса частиц методом системы итерированных функций используютсяпараметры отображений, задающих ориентацию топологических пространств роста крис-таллических элементов иерархической структуры тетр

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Gopal, Ajay K., Ted A. Gooley, Joseph Rajendran, et al. "A Phase II Trial of Myeloablative I-131-Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Transplantation for B-Cell Non-Hodgkin's Lymphoma." Blood 120, no. 21 (2012): 811. http://dx.doi.org/10.1182/blood.v120.21.811.811.

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Abstract Abstract 811 Background: High-dose therapy and autologous hematopoietic stem cell transplantation (ASCT) is the standard of care for many patients (pts) with high-risk or relapsed B-cell non-Hodgkin lymphoma (B-NHL). Despite the use of transplant, relapse is likely for most with indolent or mantle cell lymphoma (MCL) as well as for aggressive B-NHL recurring after rituximab (R)-based chemotherapy. Total body irradiation (TBI) has been incorporated into ASCT regimens to overcome chemotherapy resistance and improve outcomes, but studies to date indicate that escalation of TBI is not fea

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Araji, Ghada, Ahmad Mustafa, Chapman Wei, et al. "Monoclonal Gammopathy of Undetermined Significance and Associated Cardiovascular Outcomes in a Hospital Setting - a Fresh Perspective." Blood 142, Supplement 1 (2023): 6765. http://dx.doi.org/10.1182/blood-2023-181640.

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Introduction: A growing body of evidence has confirmed the association between monoclonal gammopathy of undetermined significance (MGUS) and a variety of diseases including bone disease, renal impairment, autoimmune disorders, neuropathies, secondary immunodeficiencies, and infections. Recently, there has been an emerging focus on cardiovascular (CV) outcomes in patients with MGUS. However, they have not been investigated well, especially among hospitalized patients. In our study, we investigated the association between MGUS and cardiovascular outcomes in a hospital setting using the National

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Claus, Rainer, Gabriele Ihorst, Philipp Sander, et al. "Elevated Pre-Treatment Fetal Hemoglobin Predicts Better Outcome in MDS/AML Patients Receiving 5-Aza-2'-Deoxycytidine (DAC)." Blood 128, no. 22 (2016): 3175. http://dx.doi.org/10.1182/blood.v128.22.3175.3175.

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Abstract Introduction: Aberrant DNA methylation occurs frequently in hematologic malignancies and is associated with altered gene expression. Consequently, DNA hypomethylating agents (HMAs), e.g. 5-aza-2'-deoxycytidine (DAC), have been tested for in vivo demethylation and have become accepted as first-line treatment of older MDS and AML patients (pts). While HMAs are already routinely used for the treatment of MDS and AML, only very few outcome predictors have been established thus far. Expression of the β-like globin gene locus is tightly regulated by methylation, is HMA-sensitive in vitro, a

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Ruppert, Amy S., Levi D. Pederson, Michael V. Knopp, et al. "Local Review Versus (vs) Central Review of Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) in Diffuse Large B-Cell Lymphoma (DLBCL): Results from the CALGB 50303 Trial [Alliance]." Blood 136, Supplement 1 (2020): 50. http://dx.doi.org/10.1182/blood-2020-139979.

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Background FDG-PET is used in staging and response assessments in patients (pts) with DLBCL. An analysis of 158 pts with DLBCL receiving R-CHOP or DA-EPOCH-R on CALGB/Alliance 50303 failed to show an association between the interim PET (iPET, after cycle 2 of therapy) visual 5-point scale score (5-PS) by central review and progression-free survival (PFS) or overall survival (OS), but did show a significant association between percent change in FDG uptake from baseline to after cycle 2 (∆SUV) and PFS/OS (Schoder et al. 2020). As central review of FDG-PET is not feasible in routine practice, we

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Gerotziafas, Grigorios T., Flora Zagouri, Despina Fotiou, et al. "Newly Diagnosed Multiple Myeloma Is Associated with Enhanced TF Pathway Activation, Thrombin Generation and Increased Concentration of Procoagulant Microparticles." Blood 126, no. 23 (2015): 1074. http://dx.doi.org/10.1182/blood.v126.23.1074.1074.

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Abstract Background: Multiple myeloma (MM) and plasma cell dyscrasias (PCD) are associated with increased risk of venous thromboembolism (VTE) which is further enhanced by treatments with immunomodulatory agents, melphalan or steroids. The optimization of VTE prevention in patients with MM is an unmet need. According to Virchow's triad, blood hypercoagulabilty is one of the three conditions required for thrombosis. Elaboration of a risk assessment model, which includes biomarkers of hypercoagulability, could lead to better identification of MM patients eligible for pharmacological thromboproph

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Hens, Luc, Nguyen An Thinh, Tran Hong Hanh, et al. "Sea-level rise and resilience in Vietnam and the Asia-Pacific: A synthesis." VIETNAM JOURNAL OF EARTH SCIENCES 40, no. 2 (2018): 127–53. http://dx.doi.org/10.15625/0866-7187/40/2/11107.

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Climate change induced sea-level rise (SLR) is on its increase globally. Regionally the lowlands of China, Vietnam, Bangladesh, and islands of the Malaysian, Indonesian and Philippine archipelagos are among the world’s most threatened regions. Sea-level rise has major impacts on the ecosystems and society. It threatens coastal populations, economic activities, and fragile ecosystems as mangroves, coastal salt-marches and wetlands. This paper provides a summary of the current state of knowledge of sea level-rise and its effects on both human and natural ecosystems. The focus is on coastal urban

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Aljamei, Hadeel Salah, Noha Mukhtar, Sedra Mazi, et al. "MON-520 How Does the American Joint Committee on Cancer 8thEdition Tumor, Node, Metastasis Staging System Perform in Patients Evaluated at a Major Middle Eastern Medical Center?" Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.1073.

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Abstract The American Joint Committee on Cancer (AJCC) Tumor Node Metastasis (TNM) Classification of Cancer 8th edition (AJCC8) was officially introduced in January 2018 as a replacement for the previous version (AJCC7). Validation studies using data obtained from large cancer registries in North America demonstrated the superiority of AJCC8 over AJCC7 for prediction of survival. Subsequent studies from Europe and East Asia have mostly shown similar findings. However, these data may not be generalizable to other parts of the world. In this first study from the Middle East (Saudi Arabia), we co

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Sonikian, Makrouhi, Aikaterinh Velentza, Theodoros Chiras, et al. "MO805: Combination of Conventional Haemodialysis with Haemoperfusion: Does it Provide any Benefits to Haemodialysis Patients?" Nephrology Dialysis Transplantation 37, Supplement_3 (2022). http://dx.doi.org/10.1093/ndt/gfac082.003.

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Abstract BACKGROUND AND AIMS Conventional haemodialysis (HD) with low-flux membranes does not provide adequate middle molecular weight (MMW) clearance of uremic toxins [1]. The potential for better removal of parathyroid hormone (PTH) and β2-microglobulin (β2M) was investigated using a combination of low-flux HD and haemoperfusion (HP) (HD + HP). METHOD A total of 16 stable HD male patients, free of infections, malignancies or haematological disorders, under usual medications for anaemia and hyperparathyroidism, treated with low-flux polysulfone membranes, were randomized into two groups: grou

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Nair, Anand R., Masashi Mukohda, Larry N. Agbor та ін. "Effects of endothelial‐specific interference with PPARγ activity in offspring born from AVP‐induced preeclamptic pregnancies". FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.1033.2.

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PPARγ is a ligand‐activated transcription factor known to regulate metabolic and vascular function. Dominant‐negative (DN) mutations in PPARγ result in hypertension, and synthetic agonists of PPARγ have been shown to reduce blood pressure. Previously we found that mice expressing DN PPARγ driven by an endothelium‐specific promoter (E‐DN) exhibit vascular dysfunction. Preeclampsia (PE) is a hypertensive disorder of pregnancy which programs cardio/metabolic disease in offspring. PE is associated with vascular dysfunction, and we therefore hypothesized a role for endothelial PPARγ in the pathogen

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Hong Son, Bui, Vu Van Nga, Le Thi Diem Hong, and Do Thi Quynh. "Potent Natural Inhibitors of Alpha-Glucosidase and the Application of Aspergillus spp. in Diabetes type 2 Drugs: a Review." VNU Journal of Science: Medical and Pharmaceutical Sciences 38, no. 1 (2022). http://dx.doi.org/10.25073/2588-1132/vnumps.4334.

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Diabetes Mellitus has been becoming a disease of the century, and disease incidence is still rising worldwide. It causes many serious complications, especially in the eye, heart, kidneys, brain, and vascular system, such as diabetic nephropathy, diabetic retinopathy, liver failure, etc. Moreover, the process of controlling this disease is complicated. Meanwhile, the antidiabetic drugs on the market are facing some problems with a wide range of adverse reactions. Therefore, finding new drugs to treat diabetes has always been a topic that many researchers are interested in, especially drugs der

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Dolomatov, S.I., та W. Zukow. "Эпигенетика почек = Kidneys epigenetics". 7 липня 2019. https://doi.org/10.5281/zenodo.3270754.

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<strong>Dolomatov S.I., Zukow W. </strong><strong>Эпигенетика почек</strong><strong> = Kidney</strong><strong>s</strong><strong> epigenetics</strong><strong>. </strong><strong>RSW. Radom,</strong><strong> 144 </strong><strong>p. ISBN </strong><strong>9780359774524</strong><strong>.</strong><strong> DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.3270699</strong><strong> PBN Poland </strong><strong>https://pbn.nauka.gov.pl/sedno-webapp/works/917606</strong>           <strong>Radomska Szkoła Wyższa w Radomiu, Radom, Poland</strong>         &nbsp

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