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1

Eshonkhodjaev, O. D., Sh U. Rakhimiy, and V. A. Porhanov. "Comparative Study of Surgical Approaches for Mediastinal Masses." Innovative Medicine of Kuban 10, no. 2 (2025): 16–23. https://doi.org/10.35401/2541-9897-2025-10-2-16-23.

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Background: Treatment of mediastinal masses poses a significant challenge in modern thoracic surgery. Video-assisted thoracic surgery (VATS) is gaining popularity due to its minimally invasive approach compared with traditional methods, such as thoracotomy and sternotomy.Objective: To study differences in intraoperative and perioperative periods among patients who underwent VATS, thoracotomy, or sternotomy.Material and methods: The study included a total of 616 patients with mediastinal masses who underwent surgery at the Republican Specialized Scientific Practical Medical Center of Surgery na
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Mai, Phuong L., Mark E. Sherman, Marion Piedmonte, et al. "Pathologic findings at risk-reducing salpingo-oophorectomy among women at increased ovarian cancer risk: Results from GOG-199." Journal of Clinical Oncology 30, no. 15_suppl (2012): 1519. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.1519.

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1519 Background: Although risk-reducing salpingo-oophorectomy (RRSO) is a standard management option for women with BRCA1/2 mutations, the lack of large, prospective cohort studies makes estimating the prevalence of cancer at RRSO problematic. Methods: GOG-199 is a large, non-randomized multi-center trial which enrolled women at high-risk (due to BRCA mutations or strong family history) of ovarian cancer, comparing surgery at enrollment with serial transvaginal ultrasound and CA-125 screening. RRSO specimens were processed according to a standardized tissue processing protocol including 2-3mm
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Pessôa Filho, Dalton Müller, Astor Reis Simionato, Leandro Oliveira da Cruz Siqueira, Mário André Espada, and Daniel Pestana. "INFLUÊNCIA DA COMPOSIÇÃO CORPORAL REGIONAL E TOTAL SOBRE O DESEMPENHO DE NADO E ÍNDICES AERÓBIOS." Revista Brasileira de Medicina do Esporte 22, no. 3 (2016): 195–99. http://dx.doi.org/10.1590/1517-869220162203151766.

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RESUMO Introdução: Poucos estudos analisaram a contribuição da composição regional de nadadores para o perfil aeróbio, anaeróbio e o desempenho de nado. Objetivo: Verificar a influência da composição corporal regional e total sobre índices da aptidão aeróbia e anaeróbia em nado atado e livre, bem como sobre o desempenho de curta e média duração. Métodos: Onze nadadores (18,0 ± 4,0 anos) foram submetidos a: (1) teste incremental em nado atado, com coleta de gases respiração-a-respiração (K4b2 associado ao novo-AquaTrainerâ); e (2) tempo limite nos desempenhos de 200, 400 e 800 metros de nado li
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Nunes, R. D. M., I. M. S. Sales, S. I. O. Silva, J. M. C. Sousa, and A. P. Peron. "Antiproliferative and genotoxic effects of nature identical and artificial synthetic food additives of aroma and flavor." Brazilian Journal of Biology 77, no. 1 (2017): 150–54. http://dx.doi.org/10.1590/1519-6984.12115.

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Abstract This study aimed to analyze the antiproliferative and genotoxic potential of synthetic food flavorings, nature identical passion fruit and artificial vanilla. This assessment used root meristem cells of Allium cepa L., in exposure times of 24 and 48 hours and using doses of 0.2; 0.4 and 0.6 mL. Roots were fixed in Carnoy’s solution, hydrolyzed in hydrochloric acid, stained with acetic orcein and analyzed with optical microscope at 400× magnification, 5,000 cells for each treatment. For data analysis, it was used Chi-square test at 5%. Doses of 0.2 mL at ET 48 h; 0.4 and 0.6 mL at ET 2
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Jumaa, Klaudia, Badria Al Johani, Muriel Brackstone, and Anat Kornecki. "A Single-Institute Experience With Radioactive Seed Localization of Breast Lesions—A Retrospective Study." Canadian Association of Radiologists Journal 71, no. 1 (2020): 58–62. http://dx.doi.org/10.1177/0846537119885682.

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Objectives: To assess the benefits associated with radioactive seed localization (RSL) in comparison to conventional wire localization (WL) for nonpalpable breast lesions. Methods: Radioactive seed localization was initiated at our institution in July 2013. Retrospective review of all WL performed between June 2012 and July 2013 (2013) and all RSL performed during June 2015 and July 2016 (2016). Patients who received neoadjuvant therapy or did not undergo their planned surgeries and WL performed in 2016 were excluded. The following data were collected: final pathology, resection margins for ma
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Rakshit, Suvendu. "Broad line region and black hole mass of PKS 1510-089 from spectroscopic reverberation mapping." Astronomy & Astrophysics 642 (October 2020): A59. http://dx.doi.org/10.1051/0004-6361/202038324.

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Reverberation results of the flat spectrum radio quasar PKS 1510-089 from 8.5 years of spectroscopic monitoring carried out at Steward Observatory over nine observing seasons between December 2008 and June 2017 are presented. Optical spectra show strong Hβ, Hγ, and Fe II emission lines overlying on a blue continuum. All the continuum and emission line light curves show significant variability with fractional root-mean-square variations of 37.30 ± 0.06% (f5100), 11.88 ± 0.29% (Hβ), and 9.61 ± 0.71% (Hγ); however, along with thermal radiation from the accretion disk, non-thermal emission from th
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Addison, Poppy, Toni Iurcotta, Leo I. Amodu, et al. "Outcomes following operative vs. non-operative management of blunt traumatic pancreatic injuries: a retrospective multi-institutional study." Burns & Trauma 4 (December 1, 2016): 1–7. http://dx.doi.org/10.1186/s41038-016-0065-5.

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Abstract Background Traumatic pancreatic injuries are rare, and guidelines specifying management are controversial and difficult to apply in the acute clinical setting. Due to sparse data on these injuries, we carried out a retrospective review to determine outcomes following surgical or non-surgical management of traumatic pancreatic injuries. We hypothesize a higher morbidity and mortality rate in patients treated surgically when compared to patients treated non-surgically. Methods We performed a retrospective review of data from four trauma centers in New York from 1990–2014, comparing pati
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Lee, Jang-kyu. "EFFECTS OF EXERCISE TYPE AND INTENSITY ON VISFATIN AND THE METABOLIC SYNDROME IN OBESITY." Revista Brasileira de Medicina do Esporte 27, no. 2 (2021): 170–73. http://dx.doi.org/10.1590/1517-8692202127022020_0088.

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ABSTRACT Objective: Visfatin may regulate a variety of physiological functions and it has great potential to significantly enhance our knowledge of the treatment of metabolic syndrome. Metabolic syndrome (MS) refers to metabolic abnormalities, such as abdominal obesity, dyslipidemia, high low-density cholesterol, high blood pressure and diabetes, and physical activity is an important factor for the management of MS. Therefore, the purpose of this study is to investigate the effects of visfatin on MS and MS risk factors through differences in aerobic exercise intensity and exercise type based o
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Ganz, P. A., S. R. Land, D. L. Wickerham, et al. "The Study of Tamoxifen and Raloxifene (STAR): Change in patient-reported outcomes (PROs) after the end of treatment." Journal of Clinical Oncology 25, no. 18_suppl (2007): 1506. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.1506.

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1506 Background: STAR is a double-blind, placebo controlled, randomized phase III prevention trial to evaluate the efficacy of 5 years of raloxifene (R) compared to tamoxifen (T) in reducing the incidence of breast cancer in high-risk postmenopausal women. STAR was unblinded on 3/30/2006. Primary clinical outcomes, quality of life (QOL) and symptoms (SXs) were reported (JAMA, 6/2006). We now describe changes in QOL and SXs post-treatment. Methods: Endpoints for QOL were the MOS SF-36 physical (PCS) and mental (MCS) component scales and the CES-D. SXs were measured using a modified checklist fr
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Кузикеев, Жанат Владимирович, Григорий Михайлович Мусалитин, and Вера Анатольевна Борадулина. "SELECTION OF NEW OATS VARIETIES IN ALTAI TERRITORY." Вестник Бурятской государственной сельскохозяйственной академии имени В. Р. Филиппова, no. 4(57) (December 20, 2019): 95–100. http://dx.doi.org/10.34655/bgsha.2019.57.4.014.

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Россия занимает лидирующее место в мире по производству зерна овса, который является одной из основных зернофуражных культур в Сибири. По площади возделывания этой культуры Алтайский край стоит на первом месте в Российской Федерации: ежегодно под неё отводится около 400 тыс. га, что соответствует 13,3% занимаемой овсом площади в стране и 32,4 % в Сибирском федеральном округе. В Алтайском селекционном центре в 2018 году на Государственное испытание передано два сорта овса: Вектор (селекционная линия Мутика 3058) и Русич (селекционная линия Мутика 3097). Мутика 3058 получена от скрещивания местн
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11

Kumar, Sarvesh, Rinku Bhaskar, Subhash Chandra, et al. "Screening of Mungbean [Vigna radiata (L.) Wilczek] Genotypes against Cercospora Leaf Spot Caused by (Cercospora canescens) for Disease Resistance." International Journal of Environment and Climate Change 13, no. 12 (2023): 250–55. http://dx.doi.org/10.9734/ijecc/2023/v13i123681.

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In India, where vegetarianism is the norm, mungbean [Vigna radiata (L.) Wilczek] is a significant source of proteins, minerals, and vitamins. One of the most significant fungal diseases, Cercospora leaf spot caused by Cercospora canescens, appears every year with varying intensity and significantly reduces yield. The objective of the current studies was to test 100 genotypes for resistance to Cercospora canescens in vivo at the Student's Instructional Farm (S.I.F.) A.N.D.U.A. &T., Kumarganj, Ayodhya. According to the rating system, which is based on the severity of the disease, different g
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Rodriguez, Erika F., Ricardo G. Pastorello, Paul Morris, Mauro Saieg, Sayanan Chowsilpa, and Zahra Maleki. "Suspicious for Malignancy Diagnoses on Pleural Effusion Cytology." American Journal of Clinical Pathology 154, no. 3 (2020): 394–402. http://dx.doi.org/10.1093/ajcp/aqaa058.

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Abstract Objectives A definitive diagnosis of malignancy may not be possible in pleural effusions. We report our experience with the diagnosis of suspicious for malignancy (SFM) in pleural effusion. Methods A search for pleural effusions diagnosed as SFM (2008-2018) was performed. Patient records and pathology reports were reviewed. Specimens were subdivided into groups depending on volume (<75, 75-400, >400 mL). Diagnoses of malignant pleural effusion (MPE) served as controls. Results We identified 90 patients, with a mean age of 60.6 years. Diagnoses included suspicious for inv
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Cadée, Gerhard C. "Book review: Red Tides. Edited by Tomotoshi Okaichi, 2004, XIII + 439 pp. (Hardbound). Kluwer Academic Publishers, Dordrecht. ISBN 1-4020-1512-7. Price: € 90.00, US$ 99.00, GB £ 62.00." Aquatic Ecology 39, no. 2 (2005): 259. http://dx.doi.org/10.1007/s10452-005-5202-3.

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14

Florence, Eric, Christa Dreezen, Patrick Desmet, et al. "Ritonavir/Saquinavir plus One Nucleoside Reverse Transcriptase Inhibitor (NRTI) versus Indinavir plus Two Nrtis in Protease Inhibitor-Naive HIV-1-Infected Adults (Iris Study)." Antiviral Therapy 6, no. 4 (2000): 255–62. http://dx.doi.org/10.1177/135965350200600405.

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Objectives To compare the efficacy, tolerability and safety of a ritonavir 400 mg/saquinavir hard gel fomulation 400 mg twice daily versus an indinavir 800 mg once every 8 h containing first-line protease inhibitor (PI) treatment regimen. Methods Open, randomized, multicentre clinical trial. PI-naive patients received either ritonavir/saquinavir and one nucleoside reverse transcriptase inhibitor (NRTI) or indinavir and two NRTIs. Intention-to-treat (ITT) and on-treatment (OT) analyses were performed. Results The baseline characteristics of the study participants were similar in both arms, 67 p
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15

Gerber, David E., Jodi B. Segal, M. Yair Levy, Joyce Kane, Richard J. Jones, and Michael B. Streiff. "The incidence of and risk factors for venous thromboembolism (VTE) and bleeding among 1514 patients undergoing hematopoietic stem cell transplantation: implications for VTE prevention." Blood 112, no. 3 (2008): 504–10. http://dx.doi.org/10.1182/blood-2007-10-117051.

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AbstractVenous thromboembolism (VTE) is increasingly diagnosed among individuals with hematologic malignancies. However, the risk of VTE among patients undergoing hematopoietic stem cell transplantation (HSCT) is unclear. We examined the incidence and risk factors for VTE and bleeding among 1514 patients undergoing in-patient HSCT. No protocolized VTE prophylaxis was used. By HSCT day 180, 75 symptomatic VTE occurred in 70 patients (4.6%; 95% confidence interval [CI], 3.6%-5.8%). Fifty-five (3.6%) were catheter-associated, 11 (0.7%) were non–catheter-associated deep venous thromboses, and 9 (0
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Simon, Dominique, Corinne Alberti, Marianne Alison, et al. "Effects of Recombinant Human Growth Hormone for 1 Year on Body Composition and Muscle Strength in Children on Long-Term Steroid Therapy: Randomized Controlled, Delayed-Start Study." Journal of Clinical Endocrinology & Metabolism 98, no. 7 (2013): 2746–54. http://dx.doi.org/10.1210/jc.2012-4201.

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Context: Recombinant human GH (rhGH) improves growth and body composition in glucocorticoid-treated children. Its effects on muscle strength are poorly evaluated. Objectives: Our objective was to evaluate rhGH effects on muscle strength in children receiving long-term glucocorticoid therapy; effects on height SD score (SDS) and body composition were assessed also. Design and Setting: A randomized, controlled, delayed-start study of rhGH for 12 months was started after randomization (baseline) or 6 months later (M6). Patients: Patients included 30 children with various diagnoses. Intervention:
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Ananworanich, Jintanat, Meena Gorowara, Anchalee Avihingsanon, et al. "Pharmacokinetics of and Short-Term Virologic Response to Low-Dose 400-Milligram Once-Daily Raltegravir Maintenance Therapy." Antimicrobial Agents and Chemotherapy 56, no. 4 (2012): 1892–98. http://dx.doi.org/10.1128/aac.05694-11.

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ABSTRACTBecause studies showed similar viral suppression with lower raltegravir doses and because Asians usually have high antiretroviral concentrations, we explored low-dose raltegravir therapy in Thais. Nineteen adults on raltegravir at 400 mg twice daily (BID) with HIV RNA loads of <50 copies/ml were randomized to receive 400 mg once daily (QD) or 800 mg QD for 2 weeks, followed by the other dosing for 2 weeks. Intensive pharmacokinetic analyses were performed, and HIV RNA was monitored. Two patients were excluded from the 400-mg QD analysis due to inevaluable pharmacokinetic data. The m
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Li, Yuzhi, Shiquan Cui, Samuel Baidoo, and Lee Johnston. "Evaluation of Sow Caliper for body condition measurement of gestating sows." Journal of Swine Health and Production 29, no. 5 (2021): 245–52. http://dx.doi.org/10.54846/jshap/1232.

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Objectives: To evaluate correlation between Sow Caliper measurement and backfat depth (BFD), and to determine the ideal caliper measurement that predicts optimal BFD prefarrowing to support performance of lactating sows. Materials and methods: Multiparous sows (n = 928, Parity 1-9) were group housed in pens from day 35 to 109 of gestation. Caliper measurements, BFD, visual body condition scores (BCS), and body weight were recorded upon sows’ entry and exit of gestation pens. Subsequent farrowing performance was recorded. Caliper measurements were classified into five categories: category 1 = 4
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Salem, Hytham S., Laura J. Huston, Alexander Zajichek, et al. "Anterior Cruciate Ligament Reconstruction With Concomitant Meniscal Repair: Is Graft Choice Predictive of Meniscal Repair Success?" Orthopaedic Journal of Sports Medicine 9, no. 9 (2021): 232596712110335. http://dx.doi.org/10.1177/23259671211033584.

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Background: When meniscal repair is performed during anterior cruciate ligament (ACL) reconstruction (ACLR), the effect of ACL graft type on meniscal repair outcomes is unclear. Hypothesis: The authors hypothesized that meniscal repairs would fail at the lowest rate when concomitant ACLR was performed with bone--patellar tendon--bone (BTB) autograft. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who underwent meniscal repair at primary ACLR were identified from a longitudinal, prospective cohort. Meniscal repair failures, defined as any subsequent surgical procedure addre
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Ertem, Ahmet Goktug, Yasin Ozen, Baran Yuksekkaya, et al. "Association of the Novel Inflammatory Marker Systemic Immune-Inflammation index and Contrast-Induced Nephropathy in Patients Undergoing Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis." Angiology 73, no. 5 (2022): 422–30. http://dx.doi.org/10.1177/00033197211045031.

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This study investigated whether the systemic immune-inflammation index (SII) is an independent predictor of contrast-induced nephropathy (CIN) in patients undergoing transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. TAVR patients (n = 130) were included in the study. The patients were divided into 2 groups: those who developed CIN [CIN (+)] and those who did not [CIN (−)]. The SII was calculated as the ratio of the product of the total neutrophil count and the total platelet count to the lymphocyte count. CIN developed in 20 (15.3%) patients after TAVR. White blood cell
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Munir, M., SNH Shah, U. Almas, et al. "An assessment of the wound healing potential of a herbal gel containing an Azadirachta indica leaf extract." Veterinární Medicína 66, No. 3 (2021): 99–109. http://dx.doi.org/10.17221/46/2020-vetmed.

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The objective of this study was to produce a Carbopol 940 based gel formula containing an Azadirachta indica leaf extract and evaluate its wound healing potential. The ethanolic extract was derived from the dried leaves of Azadirachta indica and was subjected to a phytochemical evaluation. Three gel formulations of Carbopol 940 containing an Azadirachta indica extract in three different concentrations, i.e., 1, 2, and 3% w/w were prepared. These gels were evaluated for their physical appearance, stability, antimicrobial activity, extrudability, skin irritability, pH, spreadability, and viscosi
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Armstrong, April W., Mark Lebwohl, Richard B. Warren, et al. "Deucravacitinib in Plaque Psoriasis: 4-year Safety and Efficacy Results from the Phase 3 POETYK PSO-1, PSO-2, and LTE Trials." SKIN The Journal of Cutaneous Medicine 8, no. 6 (2024): s423. http://dx.doi.org/10.25251/skin.8.supp.423.

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Introduction: Deucravacitinib, an oral, selective, allosteric TYK2 inhibitor, is approved in multiple countries for treatment of adults with moderate to severe plaque psoriasis who are candidates for systemic therapy. Deucravacitinib was superior to placebo and apremilast in the global, 52-week, phase 3 POETYK PSO-1 and PSO-2 parent trials in moderate to severe plaque psoriasis. Upon completion, patients could enroll in the ongoing POETYK long-term extension (LTE) trial. Here, deucravacitinib safety/efficacy are reported through 4 years. Methods: PSO-1/PSO-2 randomized patients 1:2:1 to oral p
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Silvain, Johanne, Lee S. Nguyen, Vincent Spagnoli, et al. "Contrast-induced acute kidney injury and mortality in ST elevation myocardial infarction treated with primary percutaneous coronary intervention." Heart 104, no. 9 (2017): 767–72. http://dx.doi.org/10.1136/heartjnl-2017-311975.

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ObjectivesContrast-induced acute kidney injury (CI-AKI) is a common and potentially severe complication in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). There is no consensus on the best definition of CI-AKI to identify patients at risk of haemodialysis or death. The objective of this study was to assess the association of CI-AKI, using four definitions, on inhospital mortality, mortality or haemodialysis requirement over 1-year follow-up, in patients with STEMI treated with pPCI.MethodsIn this prospective, observationa
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Rosti, Gianantonio, Fausto Castagnetti, Gabriele Gugliotta, et al. "Excellent Outcomes at 3 Years with Nilotinib 800 Mg Daily In Early Chronic Phase, Ph+ Chronic Myeloid Leukemia (CML): Results of a Phase 2 GIMEMA CML WP Clinical Trial." Blood 116, no. 21 (2010): 359. http://dx.doi.org/10.1182/blood.v116.21.359.359.

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Abstract Abstract 359 Background: Nilotinib is a potent and selective inhibitor of BCR-ABL. In the phase 3 ENESTnd trial, nilotinib demonstrated superior efficacy to imatinib with higher and faster molecular responses. With a median follow-up of 18.5 months (ASCO/EHA 2010), the rates of progression to accelerated or blast phase (AP/BC) were 0.7% and 0.4% with nilotinib 300 mg and 400 mg BID, respectively, and significantly lower in comparison to imatinib (4.2% P = .006 and .003, respectively). Based on the results of the ENESTnd trial, nilotinib has been approved (FDA) for the frontline treatm
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Köhm, M., A. C. Foldenauer, T. Rossmanith, et al. "POS0229 COMBINING MTX DOES NOT RESULT IN AN ADDITIONAL EFFICACY OF UST TREATMENT IN POLYARTHRITIC PSA: SUBGROUP ANALYSIS FROM A RANDOMIZED PLACEBO-CONTROLLED INVESTIGATOR INITIATED CLINICAL TRIAL." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 344–45. http://dx.doi.org/10.1136/annrheumdis-2023-eular.4112.

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BackgroundBDMARD treatment in PsA patients usually requires treatment failure/intolerance to csDMARDs. The value of MTX in combination with bDMARDs is still unclear; an increase of efficacy is expected in polyarthritis. We designed an investigator-initiated, randomized, placebo-controlled trial (IIT) in active PsA to examine if outcomes of UST in combination with MTX (either newly initiated or ongoing) are different from UST only (+PBO), especially with focus on peripheral arthritic dominant PsA.ObjectivesTo compare ACR20/50/70 and MDA response rates at week 24 in treatment groups stratified b
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Hyams, Jeffrey S., Alan M. Leichtner, Lorna O. Zamett, and J. Ken Walters. "Effect of Metoclopramide on Prolonged Intraesophageal pH Testing in Infants with Gastroesophageal Reflux." Journal of Pediatric Gastroenterology and Nutrition 5, no. 5 (1986): 716–20. http://dx.doi.org/10.1002/j.1536-4801.1986.tb09167.x.

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SummaryThe effect of metoclopramide (MCP) on prolonged intraesophageal pH testing was evaluated in 42 infants with gastroesophageal reflux (GER). Following a baseline period of intraesophageal pH monitoring, MCP was administered by injection at 0.1 mg/kg/dose (10 patients), 0.2 mg/kg/dose (11 patients), or 0.3 mg/kg/dose (21 patients). The percentage of time of intraesophageal pH less than 4, reflux frequency, and acid clearance time were calculated for each subject before and after MCP for both 5% dextrose and formula feedings. These parameters were further separated into 2‐hour or shorter an
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Tarutta, Elena P., Sergey V. Milash, Olga V. Proskurina, et al. "Comparative evaluation of choroidal thickness in children using different myopia correction methods." Russian Pediatric Ophthalmology 19, no. 4 (2024): 211–18. https://doi.org/10.17816/rpoj636256.

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AIM: To measure choroidal thickness in the cross-sectional images of myopic patients using different correction methods. MATERIAL AND METHODS: Examination included 162 patients (324 eyes) aged 9 to 19 years (mean: 11.6 ± 2.7 years), with myopia between 0.5 D to 11.75 D (mean: 4.0 ± 2.3 D) using different myopia correction methods, e.g., monofocal spectacles (MF): 96 eyes, Group 1), perifocal spectacles (40 eyes, Group 2), orthokeratology lenses (OKL) (36 eyes, group 3), bifocal soft contact lenses (BSCL) (86 eyes, Group 4), and Stellest® spectacles (66 eyes, Group 5). The anterior-posterior ax
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Mayhew, Maureen, Karen J. Grant, Lorena Mota, Setareh Rouhani, Michael C. Klein, and Arminée Kazanjian. "Facilitating refugees’ access to family doctors." International Journal of Migration, Health and Social Care 11, no. 1 (2015): 1–17. http://dx.doi.org/10.1108/ijmhsc-12-2013-0046.

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Purpose – The purpose of this paper is to describe the patient level characteristics of government-assisted refugees (GARs) who had acquired family doctors after leaving specialized refugee clinics (RC). Design/methodology/approach – A cross-sectional telephone survey of GARs households, three to six years after arrival to British Columbia, that used logistic regression to identify GAR characteristics associated with having a family doctor compared to having no family doctor or remaining at a RC. Findings – Contact rate was 52 percent. Of 177 interviewed GARs who spoke 24 languages, only 61 pe
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Yee, A., L. Siriwardhana, G. Nixon, F. Wong, and R. Horne. "P168 Pre and postnatal factors associated with periodic breathing in preterm infants." SLEEP Advances 2, Supplement_1 (2021): A76. http://dx.doi.org/10.1093/sleepadvances/zpab014.206.

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Abstract Introduction Immature cardio-respiratory control in preterm infants often manifests as periodic breathing (PB). A number of pre- and postnatal demographic and clinical factors, such as exposure to maternal smoking, respiratory support and medications may affect respiratory control. We aimed to identify specific factors affecting the frequency of PB in preterm infants before hospital discharge. Methods 32 healthy preterm infants (14M, 18F) born between 28–32 weeks of gestational age were studied for 2–3 hours with daytime polysomnography at 31–36 weeks (when they had been off respirato
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Bau, Anne-Madeleine, Sarah Krull, Andrea Ernert, and Birgit Babitsch. "Eating behaviour and its association with social living conditions and weight status among adolescent girls: results of the cross-sectional Berlin School Children's Cohort study." Public Health Nutrition 14, no. 10 (2011): 1759–67. http://dx.doi.org/10.1017/s1368980011000541.

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AbstractObjectiveTo capture a more holistic picture of eating behaviour by investigating the impact of the social living conditions and weight status of parents and daughters on food consumption frequency, the context of meals and daily portion sizes.DesignCross-sectional Berlin School Children's Cohort study.SettingA total of sixty-nine schools in Berlin (3 400 000 inhabitants, eastern Germany) participated in the present study.SubjectsA total of 1519 girls aged 11–14 years were selected. Bi- and multivariate analyses were performed to examine the impact of age, migration background, socio-ec
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Moriyama, Hiroaki, Masafumi Gotoh, Koji Tanaka, et al. "Midterm Functional and Structural Outcomes of Large/Massive Cuff Tears Treated by Arthroscopic Partial Repair." Orthopaedic Journal of Sports Medicine 9, no. 3 (2021): 232596712098879. http://dx.doi.org/10.1177/2325967120988795.

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Background: Previous studies have shown good clinical outcomes in patients with irreparable large or massive rotator cuff tears treated using arthroscopic partial repair (APR); however, few studies have evaluated both functional and structural outcomes in these patients. Purpose: To evaluate both functional and structural outcomes in patients with large or massive rotator cuff tears treated using APR. Study Design: Case series; Level of evidence, 4. Methods: Between March 2009 and November 2016, a total of 30 patients underwent APR because of the irreparability of their large or massive rotato
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Yamasaki, Alisa, Ciersten A. Burks, and Neil Bhattacharyya. "Cognitive and Quality of Life-Related Burdens of Illness in Pediatric Allergic Airway Disease." Otolaryngology–Head and Neck Surgery 162, no. 4 (2020): 566–71. http://dx.doi.org/10.1177/0194599820908202.

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Objective To analyze the prevalence of pediatric allergic airway disease (PAA) and recognize its impact on cognitive function, childhood activities, use of early intervention, and missed school days. Study Design Cross-sectional analysis of National Health Interview Survey (NHIS), 2014 to 2017. Setting US households. Subjects and Methods An NHIS survey of US children and responding caregivers was analyzed to determine the prevalence of PAA, including allergic rhinitis and allergic asthma. Associations were determined between the presence of PAA and activities limited by difficulty remembering,
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Kuenze, Christopher M., Nathaniel Foot, Susan A. Saliba, and Joseph M. Hart. "Drop-Landing Performance and Knee-Extension Strength After Anterior Cruciate Ligament Reconstruction." Journal of Athletic Training 50, no. 6 (2015): 596–602. http://dx.doi.org/10.4085/1062-6050-50.2.11.

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Context Individuals with a history of anterior cruciate ligament reconstruction (ACLR) are at greater risk of reinjury and developing early-onset osteoarthritis due to persistent abnormal joint loading. Real-time clinical assessment tools may help identify patients experiencing abnormal movement patterns after ACLR. Objective To compare performance on the Landing Error Scoring System (LESS) between participants with ACLR and uninjured control participants and to determine the relationship between LESS score and knee-extension strength in these participants. Design Controlled laboratory study.
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Thornton, Charlene Eliza, and Hannah Grace Dahlen. "Born before arrival in NSW, Australia (2000–2011): a linked population data study of incidence, location, associated factors and maternal and neonatal outcomes." BMJ Open 8, no. 3 (2018): e019328. http://dx.doi.org/10.1136/bmjopen-2017-019328.

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ObjectivesTo determine incidence, associated factors, outcomes and geographical occurrence of born before arrival (BBA) in New South Wales, Australia.DesignA linked population data study involving population-based surveillance systems was undertaken for the years 2000–2011.SettingNew South Wales, Australia.ParticipantsAll women who underwent BBA compared with women who birthed in hospital/birth centre settings.ResultsDuring the time period, there were 1 097 653 births and a BBA rate of 4.6 per 1000 births. The BBA rate changed from 4.2 to 4.8 per 1000 births over time (p=0.06). Neonates BBA we
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Pathare, Anil, Salam AlKindi, Ali AlMadhani, et al. "Predictive Value of Red Cell Indices and High Performance Liquid Chromatography in the Diagnosis of Haemoglobinopathies: Interim Results of the National Neonatal Cord Blood Screening Programme." Blood 108, no. 11 (2006): 3352. http://dx.doi.org/10.1182/blood.v108.11.3352.3352.

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Abstract Objective: The aim of the study was to ascertain the feasibility of cord blood screening to determine the prevalence of haemoglobinopathies by a cost-effective method. Background: High rate of consanguinity and intercousin marraiges are prevalent in the Sultanate of Oman, leading to an increase in haemoglobinopathies, which is of growing importance as knowledge of a population structure can be a unique aid in planning genetic services. Methods: 1864 consecutive cord blood samples were screened by HPLC using Biorad Variant II program between April 2005 & March 2006. Complete blood
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Gonzalez Velez, Miguel, Carolyn Mead-Harvey, Heidi E. Kosiorek, Yael Kusne, and Leslie Padrnos. "Racial Differences in Nutritional Anemias: Analysis of Folate, Vitamin B12, and Iron Deficiencies." Blood 134, Supplement_1 (2019): 3387. http://dx.doi.org/10.1182/blood-2019-123791.

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Background: Serum folate (SF), vitamin B12 (B12), and iron deficiencies (def) are common causes of nutritional anemias. These deficiencies are usually multifactorial, with nutritional and non-nutritional factors playing a role. SF, B12, and iron levels are usually ordered in the setting of anemia, and malnutrition with or without neurologic symptoms. Since folic acid fortification, the prevalence of SF def in the United States (US) is <1% in the general population. B12 def and iron def range between 6-12%, and 1-11% respectively depending on the population studied. The prevalence of nutriti
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Sanjana Devi and Revathi Duraisamy. "Correlation between Age, Gender and Habits among Children - A Retrospective Study." International Journal of Research in Pharmaceutical Sciences 11, SPL3 (2020): 418–22. http://dx.doi.org/10.26452/ijrps.v11ispl3.2956.

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Oral health influences the overall health of an individual. Hence, when oral health is affected the general well-being of the individual is unbalanced. Habits are repetitive actions done automatically. They represent an altered pattern of muscle contraction, done unconsciously and on a regular basis. Some habits are helpful, whereas other habits are deleterious over the long run. Habits can be either functional or non-functional. Functional habits include repeating normal functions unnecessarily like swallowing, chewing and nasal breathing. Whereas non-functional habits are unnecessary extra f
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Thariat, Juliette, Dawn Aranguren, Yazici Gozde, et al. "Chemotherapy with irradiation in salivary gland carcinomas (SGC): A Rare Cancer Network study (RCN)." Journal of Clinical Oncology 31, no. 15_suppl (2013): e17019-e17019. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e17019.

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e17019 Background: To report the role of combined chemotherapy in SGT. Methods: 251 patients with SGC treated in 2001-2011 were included in a collaborative IRB-approved retrospective RCN study. Chemotherapy is empirically administered based on extrapolation from conventional head and neck squamous cell carcinoma (Ca) (SCC) and data on systemic treatment in localized SGC are lacking. Results: Median age was 60 yo with 2/5 females/males. Tumor sites were the parotid 74.9%, submandibular 16%, sublingual 2.8% or minor gland 4%. Histologic findings were adenoid cystic (ACC) 17.3%, mucoepidermoid (M
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Limumpornpetch, Padiporn, Ann W. Morgan, Ana Tiganescu, et al. "Real World Mortality and Specific Causes of Death in Chronic Oral Glucocorticoid Use: A Systematic Review, Meta-Analysis and Meta-Regression." Journal of the Endocrine Society 5, Supplement_1 (2021): A93. http://dx.doi.org/10.1210/jendso/bvab048.186.

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Abstract Background: Glucocorticoids (GCs) are widely used as therapeutic agents with prevalence 0.9–3.7%, but they are associated with significant side effects. Understanding of mortality ratios and causes of death from GC use is poorly appreciated and likely to help shape future stratification of clinical practice. Aims: To perform a meta-analysis of all-cause and specific cause -mortality amongst chronic GC users. Methods: The protocol was registered in PROSPERO (CRD42017067530). Searches were undertaken of PubMed, EMBASE, CINHAL, web of science and Cochrane Central from 1966 to April 2019.
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Chino, Fumiko, Amy L. Tin, Emeline Mariam Aviki, and Bridgette Thom. "Longitudinal outcomes after financial toxicity and health-related social risks screening and referral." JCO Oncology Practice 20, no. 10_suppl (2024): 17. http://dx.doi.org/10.1200/op.2024.20.10_suppl.17.

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17 Background: Financial toxicity (FT) is associated with delayed/omitted care, reduced quality of life, and worse mortality. Routine screening for FT and health-related social risks (HRSR) is recommended during clinical care, but there is limited longitudinal evidence on outcomes after patients screen positive and are referred for assistance. Methods: FT and HRSR screening for patients with breast, gynecologic, gastrointestinal, or thoracic cancers was implemented at an urban comprehensive cancer center. Screening included the Comprehensive Score for Financial Toxicity (COST) tool (0-44, lowe
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Cheung, Yin Ting, Noah D. Sabin, Wilburn E. Reddick, et al. "Association Between Acute Leukoencephalopathy and Long-Term Neurobehavioral and Brain Imaging Outcomes in Survivors of Childhood Acute Lymphoblastic Leukemia Treated with Chemotherapy Only." Blood 126, no. 23 (2015): 3255. http://dx.doi.org/10.1182/blood.v126.23.3255.3255.

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Abstract Introduction: Leukoencephalopathy is observed in a subset of children undergoing chemotherapy for acute lymphoblastic leukemia (ALL), though the impact of these white matter abnormalities on long-term behavior and brain integrity are unknown. This study examines associations between acute (on-therapy) leukoencephalopathy and neurobehavioral ratings and white matter integrity in long-term survivors of ALL treated with chemotherapy only. Methods: 408 patients with newly diagnosed ALL were treated on St. Jude Total XV protocol which omitted cranial irradiation in all patients. Of the 369
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Reynaud, T., A. Bertaut, W. Farah, et al. "P14.78 Hypofractionated stereotactic radiotherapy as a salvage therapy for recurrent high-grade gliomas: Single-center experience." Neuro-Oncology 21, Supplement_3 (2019): iii86. http://dx.doi.org/10.1093/neuonc/noz126.313.

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Abstract BACKGROUND The standard of care for patients with recurrent glioblastoma or grade III glioma has not yet been clearly defined and many approaches are available for salvage strategies. These include surgery, re-irradiation or systemic agents. For the treatment of High-Grade (HGG) recurrence by radiation therapy, Hypofractionated Stereotactic Radiotherapy (HFSRT) is an interesting approach because it is minimally invasive, ambulatory, short-lasting and well tolerated. The aim of this study was to evaluate the efficacy of and safety to HFSRT as alvage treatment for patients suffering fro
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Lappe, Claudia, Holger Reinecke, Jannik Feld, and Jeanette Köppe. "Sex Differences in Ischemic Cerebral Infarction: A Nationwide German Real-Life Analysis from 2014 to 2019." Clinical and Translational Neuroscience 6, no. 3 (2022): 23. http://dx.doi.org/10.3390/ctn6030023.

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Female sex has been shown to be associated with an unfavorable outcome after ischemic stroke. In this nationwide analysis, we evaluate a large dataset of patients suffering from acute ischemic stroke to elucidate the factors associated with an increased risk of mortality after stroke in women. We analyzed a nationwide dataset from the German Federal Bureau of Statistics including 1,577,884 (761,537 female sex, 48.3%) in-hospital cases admitted between 1 January 2014 and 31 December 2019 with a primary diagnosis of acute ischemic cerebral infarction. Patients were analyzed regarding morbidity,
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44

Chaverri, Carlos, and José F. Cicció. "Essential oils of Baccharis trinervis (Asteraceae) from Costa Rica." Revista de Biología Tropical 65, no. 4 (2017): 1307. http://dx.doi.org/10.15517/rbt.v65i4.27845.

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Baccharis is an Asteraceae genus of flowering plants, which has about 340 to 400 species, ranging from the Southern United States to the Southern extreme of Argentina and Chile through Central America and the Caribbean regions. The species Baccharis trinervis is a native shrub from Mexico, Central America and throughout South America. In Costa Rica, this species is commonly known as alcotán and the fresh leaves are used as a poultice on wounds and ulcers. The objective of the present research was to characterize the chemical composition of seven hydrodistilled essential oils of diverse morphol
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Cronce, Marcia, Robert M. Rauber, Kevin R. Knupp, Brian F. Jewett, Justin T. Walters, and Dustin Phillips. "Vertical Motions in Precipitation Bands in Three Winter Cyclones." Journal of Applied Meteorology and Climatology 46, no. 10 (2007): 1523–43. http://dx.doi.org/10.1175/jam2533.1.

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Abstract The University of Alabama in Huntsville Mobile Integrated Profiling System 915-MHz profiler was deployed in January and February of 2004 to measure vertical air velocities in finescale precipitation bands in winter cyclones. The profiler was placed to sample the “wraparound” quadrant of three winter cyclones in the central and southern United States, and it obtained high-resolution measurements of the vertical structure of a series of bands in each storm. The data revealed bands that were up to 6 km deep, 10–50 km wide, and spaced about 5–20 km apart. Measurements of vertical air moti
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Bishop, T. M., H. F. Crean, J. S. Funderburk, K. J. Speed, and W. R. Pigeon. "1087 Early Session Effects of CBT-I on Insomnia and Depression." Sleep 43, Supplement_1 (2020): A413—A414. http://dx.doi.org/10.1093/sleep/zsaa056.1082.

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Abstract Introduction Cognitive behavioral therapy for insomnia (CBT-I) has been shown to reduce depressive symptomatology among patients with co-occurring insomnia and depression. Brief forms of CBT-I have been tested in various settings including primary care. As delivery formats of CBT-I broaden, it is important to enhance our understanding of what doses and what components of CBT-I, provide the optimal balance of treatment efficacy and brevity. In the present study, we examine session-by-session effects of CBT-I on insomnia and depression. Methods Fifty-four Veterans with insomnia and co-o
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Donovan, Luke, Scott Hetzel, Craig R. Laufenberg, and Timothy A. McGuine. "Prevalence and Impact of Chronic Ankle Instability in Adolescent Athletes." Orthopaedic Journal of Sports Medicine 8, no. 2 (2020): 232596711990096. http://dx.doi.org/10.1177/2325967119900962.

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Background: The prevalence and impact of chronic ankle instability (CAI) in adolescent athletes are unknown. To better develop and justify prevention strategies of lateral ankle sprains and CAI, it is important to understand the origin and associated long-term impact of CAI within populations other than adults. Purpose/Hypothesis: The purpose of this study was to determine the prevalence and impact of CAI on ankle function, health-related quality of life (HRQoL), and physical activity in adolescent athletes. The hypothesis was that the presence of CAI will be commonly reported among adolescent
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Yi, Cecilia Y. Arana, Jorge Cortes, Stefan Faderl, et al. "Final Report of Combination of Sorafenib, Idarubicin, and Cytarabine for Initial Therapy in Younger Patients with Acute Myeloid Leukemia." Blood 120, no. 21 (2012): 1516. http://dx.doi.org/10.1182/blood.v120.21.1516.1516.

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Abstract Abstract 1516 Background: Sorafenib is a potent inhibitor of FLT3 kinase with demonstrable clinical activity in patients with acute myeloid leukemia (AML) and FLT3-ITD mutation, but not those with FLT3-D835 mutation. Objectives: To determine the long term outcome of patients with AML treated with the combination of Sorafenib, cytarabine and idarubicin, and in particular those with FLT3-ITD mutation. Method: Between October 2007 to March 2010, 62 patients with newly diagnosed, previously untreated AML, were treated with Sorafenib 400 mg orally twice daily (BID) for 7 days, cytarabine 1
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Fonseca, Ana, Ana Laranjinha, and Miguel Meira e. Cruz. "0472 INSOMNIAS IN OSA PATIENTS WITH DIFERENT DEGREES OF SEVERITY: A STEP TOWARDS PHENOTYPING COMISA." SLEEP 46, Supplement_1 (2023): A209—A210. http://dx.doi.org/10.1093/sleep/zsad077.0472.

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Abstract Introduction With this pilot study, authors aimed to find how OSA and insomnias (sleep onset and maintenance insomnia) interact. Methods Data from PSG-level 1 consecutive Obstructive Sleep Apnea (OSA) patients were retrospectively collected. Insomnia and OSA severity were assessed. Arousals (A), arousal index (AI), wakefulness after sleep onset (WASO), total sleep time (TST) and sleep eficiency (SE) were used to better characterize insomnias. Epworth Sleepiness Sclae (ESS) was used to assess excessive daytime sleepiness (EDS). Results From 87 OSA patients, 43 (51.8 %): 53.5 % being fe
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Wong, Kerry, Ari R. Joffe, Jason Yap, et al. "KINDERGARTEN-AGE QUALITY OF LIFE OUTCOMES AFTER LIVER TRANSPLANTATION AT <6 YEARS." Paediatrics & Child Health 23, suppl_1 (2018): e13-e14. http://dx.doi.org/10.1093/pch/pxy054.035.

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Abstract BACKGROUND Given the improved mortality after paediatric liver transplantation, health related quality of life (HRQL) is an important outcome measure and provides valuable information for families. OBJECTIVES To determine the HRQL of kindergarten-age children who have undergone liver transplantation at age &lt;6 years old. DESIGN/METHODS Between 1999–2014, all paediatric liver transplant recipients at our center were enrolled in this ethics board approved, longitudinal inception-cohort study. Following informed consent, HRQL was measured using the parent completed Pediatric Quality of
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