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1

Almeida, Juliana F., Giuliana N. B. Sales, Marcos E. B. Brito, Pedro D. Fernandes, Walter S. Soares Filho, and Isidro P. Almeida Neto. "Salt balance in substrate cultivated with ‘Sunki’ mandarin x ‘Swingle’ citrumelo hybrids." Revista Brasileira de Engenharia Agrícola e Ambiental 22, no. 7 (2018): 493–98. http://dx.doi.org/10.1590/1807-1929/agriambi.v22n7p493-498.

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ABSTRACT During initial plant development stage, an experiment was conducted to evaluate the balance of salts in the substrate used for the production of 10 hybrids from the cross between ‘Sunki’ mandarin (TSKC) and ‘Swingle’ citrumelo (CTSW), all with potential to be used as rootstock. ‘Rangpur Santa Cruz’ lime, ‘Sunki Tropical’ mandarin and the hybrid LVK (‘Volkamer’ lemon) x LCR (‘Rangpur’ lime) - 038 were included as controls, totaling 13 genotypes. Substrate samples were collected in the experiment conducted in a greenhouse at the Federal University of Campina Grande, Campus of Pombal, fr
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Lu, Yilei, Zekun Zhou, and Ding Pan. "Genetic insights into the roles of fatty acids and gut microbiota in osteoarthritis: A Mendelian randomization study." Medicine 103, no. 49 (2024): e40674. https://doi.org/10.1097/md.0000000000040674.

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Traditional observational studies have shown that fatty acids and gut microbiota are crucial in osteoarthritis (OA) progression, but their findings are often conflicting due to biases, confounding factors, and measurement errors. We conducted a two-sample Mendelian randomization analysis using genome-wide association study data on fatty acids from 136,016 individuals, the gut microbiota from 7738 individuals, and osteoarthritis from 314,870 individuals. Elevated levels of total (odds ratio [OR]: 0.92; 95% CI 0.84–1.00; P = .039), saturated fatty acids (OR: 0.91; 95% CI 0.84–0.99; P = .034), an
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Bridge, Erica, Simron Singh, Amanda Murdoch, Mindaugas Mozuraitis, Brett Nicholls, and Lesley Moody. "Examining patient and visit characteristics associated with the cancer patient experience." Journal of Clinical Oncology 37, no. 27_suppl (2019): 204. http://dx.doi.org/10.1200/jco.2019.37.27_suppl.204.

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204 Background: Your Voice Matters (YVM) is a 28-item patient experience survey for adult cancer outpatients undergoing treatment in Ontario.The purpose was to examine patient and visit characteristics associated with YVM responses. Methods: YVM was administered to eligible patients (n=8,704) at 14 centres in 2017.Respondents answered items on a five-point Likert scale (4 or 5 = positive response). A multivariable logistic regression (MLR) was undertaken for each YVM item.Variables (reference group) included: disease site (heamatology), age group (65+), sex (female), rurality (urban), last vis
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Mpofu, S. I., and K. Y. Rashid. "Vegetative compatibility groups within Fusarium oxysporum f.sp. lini from Linum usitatissimum (flax) wilt nurseries in western Canada." Canadian Journal of Botany 79, no. 7 (2001): 836–43. http://dx.doi.org/10.1139/b01-058.

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Following the discovery of substantial differences in the development and severity of Fusarium wilt in Linum usitatissimum L. (flax) wilt nurseries in western Canada, a study of the population structure of Fusarium oxysporum f.sp. lini (Bolley) Snyd. & Hans using vegetative compatibility analysis was initiated. Vegetative compatibility was determined using nitrate non-utilizing mutants. From a total of 105 isolates, 74 were assigned to 12 vegetative compatibility groups (VCG 0440-04411), 22 were not compatible with any other isolates and 9 did not produce mutants. The populations of F. oxy
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Oki, Erica, Marina N. Norde, Antônio A. F. Carioca та ін. "Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil". British Journal of Nutrition 117, № 12 (2017): 1663–73. http://dx.doi.org/10.1017/s0007114517001416.

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AbstractThe aim of the present study was to investigate the relationship of four TNF-α SNP with inflammatory biomarkers and plasma fatty acids (FA), and the interaction among them in a population-based, cross-sectional study in São Paulo, Brazil. A total of 281 subjects, aged >19 and <60 years, participated in a cross-sectional, population-based study performed in Brazil. The following SNP spanning the TNF-α gene were genotyped: -238G/A (rs361525), -308G/A (rs1800629), -857C/T (rs1799724) and -1031T/C (rs1799964). In all, eleven plasma inflammatory biomarkers and plasma FA profile were d
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van Rijckevorsel, Paul. "(043-044) Later homonyms." TAXON 58, no. 2 (2009): 667. http://dx.doi.org/10.1002/tax.582047.

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7

Alkhotani, Amal Mohammed, and Hanadi Abualela. "Prevalence and predictors of co-occurring functional seizure in patients with epilepsy at a tertiary care center in Makkah." Annals of Saudi Medicine 45, no. 3 (2025): 198–206. https://doi.org/10.5144/0256-4947.2025.198.

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BACKGROUND: A functional seizure (FS) is a paroxysmal event that resembles epileptic seizures (ES) but without associated changes in cortical activity. OBJECTIVE: To assess the prevalence of FS among ES patients admitted to the epilepsy monitoring unit (EMU) in King Abdullah Medical City (KAMC). DESIGN: A retrospective cohort study. SETTING: EMU at KAMC PATIENTS AND METHODS: EMU database from 2015 to 2023 were reviewed. Patients were included in the study if they had a diagnosis of epilepsy and recorded seizure during admission. MAIN OUTCOME MEASURES: The prevalence and the predictors of FS de
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8

Trachet, Erin E., Chelsea Holmquist, Stephanie Nagl, and Paul M. Gonzales. "Abstract 1273: Advancing precision oncology: Development and utilization of breast cancer PDX models for in vivo drug discovery." Cancer Research 85, no. 8_Supplement_1 (2025): 1273. https://doi.org/10.1158/1538-7445.am2025-1273.

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Abstract Breast cancer is a highly heterogeneous disease that poses significant challenges for drug development and personalized treatment. Patient-derived xenograft (PDX) models have emerged as essential tools for preclinical research, faithfully preserving the genetic, transcriptomic, and histopathological features of primary tumors, including intratumoral heterogeneity and the tumor microenvironment. The Nature publication, “A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology”, highlights the utility of breast PDX models in advancing preci
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Friedland, Barbara A., Holly Gundacker, Sharon L. Achilles, et al. "Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development." PLOS ONE 20, no. 1 (2025): e0312957. https://doi.org/10.1371/journal.pone.0312957.

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End-user feedback early in product development is important for optimizing multipurpose prevention technologies for HIV and pregnancy prevention. We evaluated the acceptability of the 90-day dapivirine levonorgestrel ring (DPV-LNG ring) used for 14 days compared to a dapivirine-only ring (DVR-200mg) in MTN-030/IPM 041 (n = 23), and when used for 90 days cyclically or continuously in MTN-044/IPM 053/CCN019 (n = 25). We enrolled healthy, non-pregnant, HIV-negative women aged 18–45 in Pittsburgh, PA and Birmingham, AL (MTN-030 only). Self-reports of vaginal bleeding and adherence (ring removals,
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Bąk, Tomasz. "Dorota Muszytowska (red.), Patronka filologii. Rola Biblii w rozwoju edytorstwa, badań językoznawczych i translatorskich (Warszawa: Wydawnictwo Uniwersytetu Kardynała Stefana Wyszyńskiego 2015)." Verbum Vitae 30 (December 1, 2016): 329–36. http://dx.doi.org/10.31743/vv.1726.

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Recenzja książki:Dorota Muszytowska (red.), Patronka filologii. Rola Biblii w rozwoju edytorstwa, badań językoznawczych i translatorskich (Warszawa: Wydawnictwo Uniwersytetu Kardynała Stefana Wyszyńskiego 2015). Ss. 280. PLN 28. ISBN 978-83-8090-043-1 (wersja drukowana), ISBN 978-83-8090-044-8 (wersja elektroniczna)
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Hong, Jang Hee, Eun-Heui Jin, Jae Kyu Sung, In Ae Chang, Hyojin Kang, and Sang-Il Lee. "Association of lncRNA SOX2OT rs9839776 polymorphism with gastric cancer risk in Korean: Case-control study." Medicine 102, no. 43 (2023): e35103. http://dx.doi.org/10.1097/md.0000000000035103.

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Aberrant regulation of the long non-coding RNA SRY-box transcription factor 2 overlapping transcript (SOX2OT) has been reported in various diseases including gastric cancer (GC). However, an association between the well-studied rs9839776 single nucleotide polymorphism in SOX2OT and GC susceptibility has not been reported. This study aimed to evaluate the association between the rs9839776 single nucleotide polymorphism in SOX2OT and GC risk. Genotyping of rs9839776 was conducted using TaqMan genotyping assay for 460 patients with GC and 386 controls. We found that the dominant model (CT+TT) and
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Fanaroff, Bernie, Dharam V. Lal, Tiziana Venturi, et al. "A new look at old friends – I. Imaging classical radio galaxies with uGMRT and MeerKAT." Monthly Notices of the Royal Astronomical Society 505, no. 4 (2021): 6003–16. http://dx.doi.org/10.1093/mnras/stab1540.

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ABSTRACT We have undertaken a systematic study of FR I and FR II radio galaxies with the upgraded Giant Metrewave Radio Telescope (uGMRT) and MeerKAT. The main goal is to explore whether the unprecedented few μJy sensitivity reached in the range 550–1712 MHz at the resolution of ∼4–7 arcsec reveals new features in the radio emission which might need us to revise our current classification scheme for classical radio galaxies. In this paper, we present the results for the first set of four radio galaxies, i.e. 4C 12.02, 4C 12.03, CGCG 044–046, and CGCG 021–063. The sources have been selected fro
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13

Becker, Todd, Thomas Buckley, and Denise Burnette. "KNOWLEDGE, ATTITUDES, AND PRACTICES TOWARD COVID-19 AMONG OLDER ADULTS IN PUERTO RICO." Innovation in Aging 6, Supplement_1 (2022): 156–57. http://dx.doi.org/10.1093/geroni/igac059.621.

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Abstract To better understand the dynamics of their health behaviors during the pandemic, we examined older adults’ COVID-related knowledge, attitudes, and practices (KAP). KAP theory postulates that individuals acquire knowledge about a health condition which influences their attitudes and beliefs and that these, in turn, lead to health practices. We used hierarchical regression to examine the influence of knowledge and attitudes (Step 1) on practices, controlling for health and relevant covariates (Step 2). The Step 1 association between increased knowledge and better practices (B = 0.14, p
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14

García-Selva, Adrián, Marie-Carmen Neipp, Ángel Solanes-Puchol, Beatriz Martín-del-Río, and Stewart I. Donaldson. "The PERMA+4 Positive Functioning at Work Scale: Spanish Adaptation and Validation." Psicothema 36, no. 3 (2024): 257–66. http://dx.doi.org/10.7334/psicothema2023.341.

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Background:: Donaldson & Donaldson (2021b) developed a scale to assess Positive Functioning at Work, adding four new blocks to strengthen the original PERMA framework in the workplace. The aim of the present study was to validate this scale in a Spanish sample. Method:: 698 Spanish workers participated, 59% were women and 41% were men, 71.6% were employees and 71.2% belonged to the basic worker level. Results:: Confirmatory Factor Analysis showed a good fit of the nine-factor model (χ/df = 2.441; RMSEA = .056, 90% IC (.049, .063); SRMR =. 062; CFI = .926; TLI = .916), the bifactor model (χ
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15

Shariat, Shahrokh F., Dolores J. Lamb, Michael W. Kattan, et al. "Association of Preoperative Plasma Levels of Insulin-Like Growth Factor I and Insulin-Like Growth Factor Binding Proteins-2 and -3 With Prostate Cancer Invasion, Progression, and Metastasis." Journal of Clinical Oncology 20, no. 3 (2002): 833–41. http://dx.doi.org/10.1200/jco.2002.20.3.833.

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PURPOSE: We tested the hypothesis that preoperative plasma levels of insulin-like growth factor (IGF) binding protein (BP)-2 or IGFBP-3 would predict cancer stage and prognosis in patients undergoing radical prostatectomy. MATERIAL AND METHODS: Plasma levels of IGF-I, IGFBP-2, and IGFBP-3 were measured preoperatively in 120 consecutive patients who underwent radical prostatectomy for clinically localized disease, postoperatively in 51 of these patients, in 44 healthy men, in 19 patients with metastases to regional lymph nodes, and in 10 patients with bone metastases. RESULTS: Plasma IGFBP-3 le
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Maliah, Maliah, Joni Iswan, Muhammad Kurniawan, and Muhammad Fatkur Ro’uf. "Pengaruh Kepemimpinan Dan Lingkungan Kerja Fisik Terhadap Produktivitas Prajurit Di Korem 044/Garuda Dempo Palembang." Jurnal Media Wahana Ekonomika 19, no. 4 (2023): 632–43. http://dx.doi.org/10.31851/jmwe.v19i4.11028.

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ABSTRAK
 
 Tujuan dalam penelitian ini adalah untuk mengetahui pengaruh kepemimpinan dan lingkungan kerja fisik terhadap produktivitas prajurit di KOREM 044/Garuda Dempo Palembang baik secara parsial maupun simultan. Populasi untuk penelitian ini adalah prajurit KOREM 044/Garuda Dempo Palembang. Teknik pengambilan sampel adalah teknik sampling jenuh (sensus) sehingga diperoleh sebanyak 53 prajurit. Untuk teknik pengumpulan data menggunakan kuesioner dan observasi. Teknik analisis data yang digunakan antara lain uji coba instrumen, uji asumsi klasik, analisis regresi linier berganda,
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Semenova, Lioubov I., Alexander N. Sobolev, Brian W. Skelton, and Allan H. White. "Structural Systematics of Rare Earth Complexes. XV Tris(2,2′:6′,2″-terpyridine)lanthanoid(III) Tris(perchlorate) Complexes." Australian Journal of Chemistry 52, no. 6 (1999): 519. http://dx.doi.org/10.1071/ch98046.

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Room-temperature single-crystal X-ray structure determinations of the 1 : 3 adducts of the trivalent lanthanoid perchlorates with 2,2′:6′,2″-terpyridine (‘tpy’) as crystallized from acetonitrile are recorded. The Ln = La complex is the only one of its structural type, being modelled as La(ClO4)3/tpy/MeCN/H2O (1 : 3 : 2 :2/3), trigonal P 3c1, Z = 6, a 13·063(7), c 53·04(4) Å, recorded on an interim basis, with conventional R on |F| 0·081 for No 2889 ‘observed’ (I >3σ(I)) reflections. For Ln = Ce, (Pr, Sm,) Eu and, by presumption, other intermediate members, a monosolvate is found, monoclinic
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Rahayu, Endang. "PENGARUH GAYA KEPEMIMPINAN DAN KOMITMEN ORGANISASI TERHADAP KINERJA SATUAN KOMANDO RESOR MILITER 044 GARUDA DEMPO PALEMBANG." Jurnal Manajemen 9, no. 1 (2022): 42–69. http://dx.doi.org/10.36546/jm.v9i1.510.

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Penelitian ini menguji Pengaruh Gaya Kepemimpinan dan Komitmen Organisasi Terhadap Kinerja Satuan Komando Resor Militer 044 Garuda Dempo Palembang. tujuan penelitian adalah untuk mengetahui gaya kepemimpinan dan komitmen organisasi berpengaruh secara Parsial. Dan mengetahui gaya kepemimpinan dan komitmen organisasi berpengaruh secara Simultan. Penelitian ini menggunakan Koefisien Diterminan (R2) dan Uji T (secara parsial )
 Dari hasil analisis maka hasil analisis tersebut yaitu berdasarkan pengujian secara serempak/simultan (Uji F), ternyata hasil penelitian membuktikan bahwa semua variab
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Septian, Yusman, Kurniawan Kurniawan, Nita Rosa Damayanti, and Fatmasari Fatmasari. "Pengembangan Sistem Informasi Teritorial Berbasis Web Menggunakan Framework Laravel untuk Pemantauan Sumber Daya di Korem 044/Gapo." Jurnal Teknologi Informatika dan Komputer 9, no. 2 (2023): 1118–35. http://dx.doi.org/10.37012/jtik.v9i2.1809.

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Perkembangan sistem informasi terjadi begitu cepat. Sistem informasi mempunyai peranan yang sangat penting bagi suatu organisasi. Bidang Teritorial Komando Resor Militer (KOREM) 044/Garuda Dempo (GAPO) dalam melakukan pemantauan sumber daya yang ada diwilayah Provinsi Sumatera Selatan masih dilakukan secara kurang efektif. Pemantauan membutuhkan waktu 1 hari, sehingga membuat kepala Bidang Teritorial KOREM 044/GAPO membutuhkan waktu lebih lama dalam pengambilan keputusan dikarenakan lambatnya informasi masuk. Penelitian ini dilakukan pada bidang Teritorial KOREM 044/GAPO. Tujuan dari penelitia
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20

Hijazi, Taghreed, and Naif Alsharif. "The Psychometric Characteristics of Two Versions of a Mathematics Test in Middle School "A Comparative Study." Journal of Educational and Psychological Studies [JEPS] 11, no. 1 (2017): 178–90. http://dx.doi.org/10.53543/jeps.vol11iss1pp178-190.

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The study aimed to investigate the psychometric properties of mathematics achievement test using two versions (paper-pencil and online). The two versions of three mathematics achievement tests were applied on a sample consisting of 958 students distributed to lst, 2nd and 3rd preparatory grades. Each test consisted of 30 items with four alternatives to measure students' problem solving skills and the scientific concepts. The sample of the study was randomly stratified and clustered selected. Item difficulty coefficients of the paper-pencil mathematics achievement test ranged between O.28-0.70,
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Hijazi, Taghreed, and Naif Alsharif. "The Psychometric Characteristics of Two Versions of a Mathematics Test in Middle School "A Comparative Study." Journal of Educational and Psychological Studies [JEPS] 11, no. 1 (2017): 178. http://dx.doi.org/10.24200/jeps.vol11iss1pp178-190.

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The study aimed to investigate the psychometric properties of mathematics achievement test using two versions (paper-pencil and online). The two versions of three mathematics achievement tests were applied on a sample consisting of 958 students distributed to lst, 2nd and 3rd preparatory grades. Each test consisted of 30 items with four alternatives to measure students' problem solving skills and the scientific concepts. The sample of the study was randomly stratified and clustered selected. Item difficulty coefficients of the paper-pencil mathematics achievement test ranged between O.28-0.70,
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22

&NA;. "TAK 044." Drugs in R & D 2, no. 1 (1999): 35–37. http://dx.doi.org/10.2165/00126839-199902010-00010.

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23

Cowie, Christine, Scott Walter, Ezz Wafaa, et al. "E-044." Epidemiology 23 (September 2012): 1. http://dx.doi.org/10.1097/01.ede.0000416643.52874.3e.

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Ryan, P. Barry, Tippawan Prapamontol, Parinya Panuwet, et al. "O-044." Epidemiology 23 (September 2012): 1. http://dx.doi.org/10.1097/01.ede.0000416702.24646.91.

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Turyk, Mary, Victoria Persky, Giamila Fantuzzi, et al. "S-044." Epidemiology 23 (September 2012): 1. http://dx.doi.org/10.1097/01.ede.0000416898.36816.8e.

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Ghosh, Jo Kay, Michelle Wilhelm, Katherine Hoggatt, et al. "P-044." Epidemiology 23 (September 2012): 1. http://dx.doi.org/10.1097/01.ede.0000417055.60167.e5.

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Blackburn, David C., Lauren Roberts, María C. Vallejo-Pareja, and Edward L. Stanley. "First Record of the Anuran Family Rhinophrynidae from the Oligocene of Eastern North America." Journal of Herpetology 53, no. 4 (2019): 316–23. https://doi.org/10.1670/19-044.

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Blackburn, David C., Roberts, Lauren, Vallejo-Pareja, María C., Stanley, Edward L. (2019): First Record of the Anuran Family Rhinophrynidae from the Oligocene of Eastern North America. Journal of Herpetology 53 (4): 316-323, DOI: 10.1670/19-044, URL: http://dx.doi.org/10.1670/19-044
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Kovačić, Marcelo, Radek Šanda, Jasna Vukić, Julien P. Renoult, and Mark-Anthony Falzon. "New records of the recently described Pomatoschistus nanus Engin & Seyhan, 2017 (Teleostei: Gobiidae)." Cybium 48, no. 2 (2024): 173–76. https://doi.org/10.26028/cybium/2023-044.

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Kovačić, Marcelo, Šanda, Radek, Vukić, Jasna, Renoult, Julien P., Falzon, Mark-Anthony (2024): New records of the recently described Pomatoschistus nanus Engin & Seyhan, 2017 (Teleostei: Gobiidae). Cybium 48 (2): 173-176, DOI: 10.26028/cybium/2023-044, URL: http://dx.doi.org/10.26028/cybium/2023-044
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Costa, Tania Maria, João Guilherme Costa Sperb, André Lima Roncheti, et al. "AVALIAÇÃO DA VELOCIDADE ESPECÍFICA DE CRESCIMENTO RADIAL DE FUNGOS EM ÓLEO VEGETAL RESIDUAL." Revista de Estudos Ambientais 17, no. 2 (2016): 29. http://dx.doi.org/10.7867/1983-1501.2015v17n2p29-40.

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A quantidade de resíduos oleosos gerados diariamente por indústrias de distintas áreas e o descarte inadequado de óleos residuais em ambientes domésticos e em ambientes naturais têm ocasionado preocupação mundial, devido à extensão dos danos ambientais causados por estes poluentes. Distintos fungos apresentam potencial de crescimento quando cultivados em ambientes contendo substratos oleosos. O crescimento micelial radial, bem como a cinética e a velocidade específica de crescimento de fungos filamentosos isolados de resíduos do processamento de óleo vegetal e de petróleo, foram avaliados em p
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Costa, Tania Maria, João Guilherme Costa Sperb, André Lima Roncheti, et al. "AVALIAÇÃO DA VELOCIDADE ESPECÍFICA DE CRESCIMENTO RADIAL DE FUNGOS EM ÓLEO VEGETAL RESIDUAL." Revista de Estudos Ambientais 17, no. 2 (2016): 29. http://dx.doi.org/10.7867/1983-1801.2015v17n2p29-40.

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A quantidade de resíduos oleosos gerados diariamente por indústrias de distintas áreas e o descarte inadequado de óleos residuais em ambientes domésticos e em ambientes naturais têm ocasionado preocupação mundial, devido à extensão dos danos ambientais causados por estes poluentes. Distintos fungos apresentam potencial de crescimento quando cultivados em ambientes contendo substratos oleosos. O crescimento micelial radial, bem como a cinética e a velocidade específica de crescimento de fungos filamentosos isolados de resíduos do processamento de óleo vegetal e de petróleo, foram avaliados em p
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Bayu, Eyayu Kasseye. "Determinant Variables for Women’s Participation in Soil and Water Conservation Practices in North Western Ethiopia: The Case of Shebel Berenta District (Woreda), East Gojjam Zone, Amhara National Regional State." Air, Soil and Water Research 13 (January 2020): 117862212094219. http://dx.doi.org/10.1177/1178622120942199.

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Soil erosion occurs throughout the world and is a very serious problem especially in dry land areas of Ethiopia. Rural inhabitants try to develop some erosion control measures to reduce the negative impacts; however, the role of the women is not known and deserves to be studied to understand how land degradation processes are mitigated. Hence, the main goal of this study is to identify the determinant variables of women’s participation in soil and water conservation (SWC) practices in Shebel Berenta Woreda of Amhara Region in Ethiopia as a study case. Mixed-research method with sequential expl
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Kasi, Anup, Michael Birrer, Jason Brown, et al. "Abstract B017: Phase 2 Study of NP-G2-044, a Novel Fascin Inhibitor, in Combination with Anti-PD-1 Therapy in Patients with Solid Tumors Resistant to Prior Anti-PD-1 Therapy." Cancer Immunology Research 13, no. 2_Supplement (2025): B017. https://doi.org/10.1158/2326-6074.io2025-b017.

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Abstract NP-G2-044 is a first-in-class novel fascin inhibitor that targets fascin proteins in both tumor cells and intratumoral dendritic cells (DCs). Fascin, the primary actin-bundling protein plays a critical role in cell migration and tumor metastasis. NP-G2-044 blocks tumor metastasis, reduces tumor growth, and activates intratumoral DCs by enhancing antigen uptake and increasing the population of activated DCs leading to the proliferation of CD8+ T cells. NP-G2-044 is an oral first-in-class anti-metastasis agent and simultaneously synergizes with ICIs to enhance anti-tumor immune response
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Kim, Ji Yoon, and Bu Kyung Park. "Perceptions on good death among parents of pediatric patients with hematology-oncology disease in advance." Journal of Clinical Oncology 37, no. 15_suppl (2019): e21532-e21532. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e21532.

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e21532 Background: It is difficult to perceive the preparation of a good death for children because of its social and cultural issues. Among the children with serious diseases, they can be alienated and the whole processes are done by the decision of the parent's proxy even when they have to prepare for death. The purpose of this study was to examine the perception of "Good Death" in advance among parents of pediatric patients with hematology-oncology diseases. Methods: We conducted a cross-sectional survey to parents of pediatric patients in Kyungpook National University Children’s Hospital.
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lakshmikantha, K., A. Bansal, J. Muralidharan, N. Sankhyan, and B. Medhi. "Abstract PD-044." Pediatric Critical Care Medicine 19 (June 2018): 43. http://dx.doi.org/10.1097/01.pcc.0000537446.21934.f2.

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Bea, G., N. Low, and M. Bolger. "Abstract P-044." Pediatric Critical Care Medicine 19 (June 2018): 62. http://dx.doi.org/10.1097/01.pcc.0000537501.02928.d8.

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Tiwari, Abhishek, and Anita Singh. "Synthesis and evaluation of possible mechanism of anti nociceptive potential of novel 2-quinolone fused 3,5-pyrazolidinedione derivatives in experimental animal models." Analele Universitatii "Ovidius" Constanta - Seria Chimie 24, no. 1 (2013): 5–12. http://dx.doi.org/10.2478/auoc-2013-0001.

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AbstractIn the present synthesis a series of 1-(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)-2-substituted phenylpyrazolidine-3,5-diones were prepared. By the reaction of N-methylbenzenamine with diethyl malonoate 4-hydroxy-1-methylquinolin-2(1H)-one were prepared, which on treatment with posphoryl chloride converted into 4-chloro-1-methylquinolin-2(1H)-one. Subsequently with substituted phenyl hydrazines 1-methyl-4-(2- substitutedphenylhydrazinyl)quinolin-2(1H)-one were obtained, which on reaction with diethyl malonate gave 1- (1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)-2-substituted phenylpyrazoli
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37

Benson, Lauren C., and Kristian M. O’Connor. "The Effect of Exertion on Joint Kinematics and Kinetics During Running Using a Waveform Analysis Approach." Journal of Applied Biomechanics 31, no. 4 (2015): 250–57. http://dx.doi.org/10.1123/jab.2014-0138.

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About half of all runners sustain a running-related injury every year. Exertion may contribute to risk of injury by altering joint mechanics. The purpose of this study was to examine the effects of exertion on runners’ joint mechanics using principal component analysis (PCA). Three-dimensional motion analysis of the lower extremity was performed on 16 healthy female runners before and after their typical training run. PCA was used to determine exertion-related changes in joint mechanics at the ankle, knee, and hip. Statistical significance for repeated-measures MANOVA of the retained principal
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Hagemeier, Jesper, E. Ann Yeh, Mari Heininen Brown, et al. "Iron content of the pulvinar nucleus of the thalamus is increased in adolescent multiple sclerosis." Multiple Sclerosis Journal 19, no. 5 (2012): 567–76. http://dx.doi.org/10.1177/1352458512459289.

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Objective: The objective of this paper is to assess abnormal phase values, indicative of increased iron content, using susceptibility-weighted imaging (SWI)-filtered phase of the subcortical deep gray matter (SDGM) in adolescent multiple sclerosis (MS) and other neurological disorders (OND) patients, and in healthy controls (HC). Methods: Twenty adolescent MS and eight adolescent OND patients and 21 age- and sex-matched HC were scanned on a 3T GE scanner. Mean phase of abnormal phase tissue (MP-APT), MP-APT volume, normal phase tissue volume (NPTV) and normalized volume measurements were obtai
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Ernawati, Lusi, Ratna Balgis, Takashi Ogi, Kikuo Okuyama, and Tomonori Takada. "Role of Acetone in the Formation of Highly Dispersed Cationic Polystyrene Nanoparticles." Chemical and Process Engineering 38, no. 1 (2017): 5–18. http://dx.doi.org/10.1515/cpe-2017-0002.

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Abstract A modified emulsion polymerisation synthesis route for preparing highly dispersed cationic polystyrene (PS) nanoparticles is reported. The combined use of 2,2′-azobis[2-(2-imidazolin- 2-yl)propane] di-hydrochloride (VA-044) as the initiator and acetone/water as the solvent medium afforded successful synthesis of cationic PS particles as small as 31 nm in diameter. A formation mechanism for the preparation of PS nanoparticles was proposed, whereby the occurrence of rapid acetone diffusion caused spontaneous rupture of emulsion droplets into smaller droplets. Additionally, acetone helpe
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Kim, Sangdeog Augustin. "Augustin, The Present Researcher, Says to his Wife. “Thank you my Wife Hyeonhi! And I Love you!” (Tcheonzamun 033rd-048th)." South Asian Research Journal of Humanities and Social Sciences 6, no. 06 (2024): 275–76. https://doi.org/10.36346/sarjhss.2024.v06i06.006.

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French missionary Dallet (1874) wrote in his book that ‘The thousand character essay’ has been utilized as the textbook for the children for Chinese character education. The book was used both in old China and in old Korea. The thousand character essay is called as ‘Tcheonzamun’ in Korea. Several researchers studied the translation of Tcheonzamun (The thousand character essay) poem into Korean language (Park et al., 2021a; Park et al., 2021b). The present researcher used the Tcheonzamun (The thousand character essay) book written by Han (1583). The present researcher selected the poem of the t
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Robertson, Donald S. "Genetic analyses of a putative Mutator-induced deletion involving the blue fluorescent1 (bf1) and brown midrib4 (bm4) loci in maize." Genome 39, no. 2 (1996): 433–38. http://dx.doi.org/10.1139/g96-054.

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A putative Mutator-induced alteration (isolate) involving the blue fluorescent1 (Bf1) and the brown midrib4 (bm4) loci is described. This isolate (Bf1-Mu-044-4) was one of the blue fluorescent1 mutants in a large experiment designed to produce Mutator-induced mutations involving this locus. Evidence is presented supporting the conclusion that this alteration deletes all or part of both the bf1 and bm4 loci. The isolate is infrequently transmitted through the pollen, but is more readily transmitted through the egg, although at less than the expected frequency of 50% for a simple mutation. Heter
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BRUNA, EMÍLIO DELLA, and ÁLVARO JOSÉ BACK. "COMPORTAMENTO DA CULTIVAR NIÁGARA ROSADA ENXERTADA SOBRE DIFERENTES PORTA-ENXERTOS NO SUL DE SANTA CATARINA, BRASIL." Revista Brasileira de Fruticultura 37, no. 4 (2015): 924–33. http://dx.doi.org/10.1590/0100-2945-245/14.

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RESUMO A videira ‘Niagara Rosada’ é a principal cultivar de uva de mesa plantada no Sul do Brasil. Para avaliar a qualidade da uva produzida, foi conduzido um experimento com aNiagara Rosada nos seguintes porta-enxertos: ‘Jales’, ‘Tropical’, ‘Campinas’, ‘VR 043-43’, ‘R-99’, ‘Paulsen 1103’, ‘Schwarzmann’,‘Traviú’, ‘Golias’, ‘Gravesac’, ‘RR 101-14’, ‘Dog Ridge’, ‘VR 044-4’, ‘Kobber5BB’ e ‘SO4’, mais o pé-franco. Foram avaliados a fenologia, o vigor, a sobrevivência das plantas ea produção (produtividade, tamanho do cacho e número de cachos por planta). Os diferentes porta-enxertos não influencia
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Chung, Vincent, Komal L. Jhaveri, Daniel D. Von Hoff, et al. "Phase 1A clinical trial of the first-in-class fascin inhibitor NP-G2-044 evaluating safety and anti-tumor activity in patients with advanced and metastatic solid tumors." Journal of Clinical Oncology 39, no. 15_suppl (2021): 2548. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.2548.

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2548 Background: Fascin inhibitors block tumor metastasis and increase antigen uptake in intra-tumoral dendritic cells. Filopodia, finger-like protrusions on cell surfaces, are necessary for migration of metastatic tumor cells and intra-tumoral dendritic cells. Fascin is the primary actin cross-linker in filopodia and elevated levels correlate with increased risk of metastasis, disease progression and mortality. NP-G2-044 is a novel small molecule that inhibits function of fascin. Pre-clinical data demonstrate drug-associated reductions in tumor growth and metastasis, enhanced immune response
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Kasi, Anup, Michael J. Birrer, Jason Robert Brown, et al. "Durable responses in ICI-refractory or acquired resistance: Phase 2 study of NP-G2-044 combined with anti-PD-1 therapy." Journal of Clinical Oncology 43, no. 16_suppl (2025): 2513. https://doi.org/10.1200/jco.2025.43.16_suppl.2513.

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2513 Background: Although immune checkpoint inhibitors (ICIs) have transformed cancer treatment, many patients still develop primary or acquired resistance. NP-G2-044 is a first-in-class, oral fascin inhibitor that disrupts cancer cell motility, invasion, and metastasis while promoting intratumoral dendritic cell (DC) activation and CD8+ T-cell proliferation. Preclinical studies indicate NP-G2-044 synergizes with anti-PD-1 therapy to convert nonresponsive tumors into responsive ones. Early-phase clinical data support the feasibility of NP-G2-044 at pharmacologically active doses and its potent
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Dalpubel, Daniela, Paulo Giusti Rossi, Mariana Luciano de Almeida, et al. "Subjective memory complaint and its relationship with cognitive changes and physical vulnerability of community-dwelling older adults." Dementia & Neuropsychologia 13, no. 3 (2019): 343–49. http://dx.doi.org/10.1590/1980-57642018dn13-030012.

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ABSTRACT Memory complaint (MC) is common in older adults and can be confirmed by people close to them, such as family members and caregivers. Studies show an association between MC and cognitive impairment and, hence, physical vulnerability may exacerbate MC. However, the relationship between MC and physical vulnerability is not yet clear in the literature.\ Objective: to investigate the association between MC, cognitive impairment, and physical vulnerability. Methods: this is a cross-sectional study. We evaluated 100 older adults with a mean age of 65 years or over. The Memory Complaint Scale
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Sasaki, Ritsuko, Nagomi Kurebayashi, Hidetaka Eguchi, et al. "Elucidation of the mechanisms of trastuzumab-induced severe cardiotoxicity using patient-derived iPSCs cardiomyocyte model." Journal of Clinical Oncology 40, no. 16_suppl (2022): e24065-e24065. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e24065.

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e24065 Background: Trastuzumab (Tmab) is a highly effective anticancer drug, but it is associated with unpredictable and non-accumulative cardiotoxicity, which can interfere with continuous treatment. In order to elucidate the mechanism of Tmab-induced cardiotoxicity, we attempted to reproduce the cardiotoxicity using disease-specific iPS cells from patients who had suffered myocardial dysfunction after Tmab administration. Methods: From 468 breast cancer patients treated with Tmab at our hospital, we selected three patients exhibiting severe cardiotoxicity (SP) with left ventricular ejection
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Hamamura, Kensuke, Mitsuaki Yanagida, Hitoshi Ishikawa та ін. "Quantitative measurement of a candidate serum biomarker peptide derived from α2-HS-glycoprotein, and a preliminary trial of multidimensional peptide analysis in females with pregnancy-induced hypertension". Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 55, № 2 (2017): 287–95. http://dx.doi.org/10.1177/0004563217717748.

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Purpose We previously attempted to develop quantitative enzyme-linked immunosorbent assay (ELISA) systems for the PDA039/044/071 peptides, potential serum disease biomarkers (DBMs) of pregnancy-induced hypertension (PIH), primarily identified by a peptidomic approach (BLOTCHIP®-mass spectrometry (MS)). However, our methodology did not extend to PDA071 (cysteinyl α2-HS-glycoprotein341–367), due to difficulty to produce a specific antibody against the peptide. The aim of the present study was to establish an alternative PDA071 quantitation system using liquid chromatography-multiple reaction mon
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Gudzenko, O. V., V. О. Ivanytsia та L. D. Varbanets. "Bacteria of the Black Sea are Producers of α-L-Rhamnosidase". Mikrobiolohichnyi Zhurnal 84, № 6 (2023): 10–15. http://dx.doi.org/10.15407/microbiolj84.06.010.

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The search for new producers of α-L-rhamnosidases and the study of their properties are constantly carried out, which makes it possible to identify enzymes with unique properties. Thus, the α-L-rhamnosidases producers of marine species of microorganisms can radically differ in habitat conditions from terrestrial ones. Previously, we have isolated the producers of α-L-rhamnosidases from a number of representatives of the Black Sea microbiota. However, the results of these studies did not allow us to isolate a strain promising for further study of the α-L-rhamnosidase synthesized by it. Therefor
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Honour, Patrick, and Graeme McAlpine. "044 Stemming the flow." Emergency Medicine Journal 36, no. 12 (2019): 805.2–805. http://dx.doi.org/10.1136/emermed-2019-rcem.44.

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Standardising the practice of epistaxis care in an emergency department to improve patient outcomes.Having a regional ENT centre on site we see a disproportionate number of epistaxis patients with over 500 cases a year.All atraumatic haemodynamically stable epistaxis patients who had active ongoing bleeding in the department were included.Developing a standard operating procedure based around the standard treatment arm of the NoPac study we focused on the step by step management of epistaxis to measure if this improves patient outcomes.A tailored education package for the protocol was used in
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Suharto, Nugraha, and Edy Sofyan. "MANAJEMEN PERAN SERTA MASYARAKAT DALAM PENGEMBANGAN SEKOLAH." Didaktik : Jurnal Ilmiah PGSD STKIP Subang 8, no. 2 (2023): 2608–20. http://dx.doi.org/10.36989/didaktik.v8i2.590.

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Kepmendiknas No. 044/U/2002, the government provides a forum for the community to participate and channel their aspirations in supporting education through the Board of Education at the district level and the School Committee in each education unit or group of education units (schools). With the existence of the Education Council and school committee, the level of concern and participation of the community in helping the government realize quality education is expected to be better and increase to realize community-based education. Implementation of Kepmendiknas No. 044 / U / 2002 there are se
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