Relevant bibliographies by topics / 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) / Journal articles
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Journal articles on the topic '1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)'

Author: Grafiati
Published: 4 June 2021
Last updated: 17 February 2022

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1

Karwowska, Katarzyna, Ewelina Skrodzka, Joanna Kotyńska, and Aneta D. Petelska. "Equilibria in DPPC-Diosgenin and DPPC-Diosgenin Acetate Bilayer Lipid Membranes: Interfacial Tension and Microelectrophoretic Studies." Coatings 10, no. 4 (2020): 368. http://dx.doi.org/10.3390/coatings10040368.

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Interactions between components of model lipid membranes (spherical lipid bilayers and liposomes) are investigated here. Parameters characterizing equilibria in the 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)-diosgenin (Dio) and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)-diosgenin acetate (DAc) membrane systems have been determined. The interfacial tension measurement of spherical lipid bilayers was based on the Young-Laplace’s equation using a homemade computer-controlled device. We assume a 1:1 complex in the DPPC-Dio and DPPC-DAc membrane systems. The parameters A 3 − 1 , the
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2

Juhasz, Janos, James H. Davis, and Frances J. Sharom. "Fluorescent probe partitioning in giant unilamellar vesicles of ‘lipid raft’ mixtures." Biochemical Journal 430, no. 3 (2010): 415–23. http://dx.doi.org/10.1042/bj20100516.

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Direct visualization of raft-like lo (liquid-ordered) domains in model systems and cells using microscopic techniques requires fluorescence probes with known partitioning preference for one of the phases present. However, fluorescent probes may display dissimilar partitioning preferences in different lipid sys-tems and can also affect the phase behaviour of the host lipid bilayer. Therefore a detailed understanding of the behaviour of fluorescent probes in defined lipid bilayer systems with known phase behaviour is essential before they can be used for identifying domain phase states. Using gi
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3

Soloviov, Dmytro, Yong Q. Cai, Dima Bolmatov, et al. "Functional lipid pairs as building blocks of phase-separated membranes." Proceedings of the National Academy of Sciences 117, no. 9 (2020): 4749–57. http://dx.doi.org/10.1073/pnas.1919264117.

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Biological membranes exhibit a great deal of compositional and phase heterogeneity due to hundreds of chemically distinct components. As a result, phase separation processes in cell membranes are extremely difficult to study, especially at the molecular level. It is currently believed that the lateral membrane heterogeneity and the formation of domains, or rafts, are driven by lipid–lipid and lipid–protein interactions. Nevertheless, the underlying mechanisms regulating membrane heterogeneity remain poorly understood. In the present work, we combine inelastic X-ray scattering with molecular dy
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4

Jebari-Benslaiman, Shifa, Kepa B. Uribe, Asier Benito-Vicente, et al. "Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid Composition." Biomedicines 8, no. 10 (2020): 373. http://dx.doi.org/10.3390/biomedicines8100373.

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Cardiovascular disease (CVD), the leading cause of mortality worldwide is primarily caused by atherosclerosis, which is promoted by the accumulation of low-density lipoproteins into the intima of large arteries. Multiple nanoparticles mimicking natural HDL (rHDL) have been designed to remove cholesterol excess in CVD therapy. The goal of this investigation was to assess the cholesterol efflux efficiency of rHDLs with different lipid compositions, mimicking different maturation stages of high-density lipoproteins (HDLs) occurring in vivo. Methods: the cholesterol efflux activity of soybean PC (
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5

Xu, Zhuangwei, Changchun Hao, Bin Xie, and Runguang Sun. "Effect of Fe3O4 Nanoparticles on Mixed POPC/DPPC Monolayers at Air-Water Interface." Scanning 2019 (March 3, 2019): 1–9. http://dx.doi.org/10.1155/2019/5712937.

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Fe3O4 nanoparticles (NPs) as a commonly used carrier in targeted drug delivery are widely used to carry drugs for the treatment of diseases. However, the mechanism of action of between Fe3O4 NPs and biological membranes is still unclear. Therefore, this article reports the influence of hydrophilic and hydrophobic Fe3O4 NPs on mixed 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) that were studied using the Langmuir-Blodgett (LB) film technique and an atomic force microscope (AFM). From surface pressure-area (π-A) isotherms, we have
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6

Zhang, Xinxing, Kevin M. Barraza, and J. L. Beauchamp. "Cholesterol provides nonsacrificial protection of membrane lipids from chemical damage at air–water interface." Proceedings of the National Academy of Sciences 115, no. 13 (2018): 3255–60. http://dx.doi.org/10.1073/pnas.1722323115.

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The role of cholesterol in bilayer and monolayer lipid membranes has been of great interest. On the biophysical front, cholesterol significantly increases the order of the lipid packing, lowers the membrane permeability, and maintains membrane fluidity by forming liquid-ordered–phase lipid rafts. However, direct observation of any influence on membrane chemistry related to these cholesterol-induced physical properties has been absent. Here we report that the addition of 30 mol % cholesterol to 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) or 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-r
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7

Pereira-Leite, Catarina, Daniela Lopes-de-Campos, Philippe Fontaine, Iolanda Cuccovia, Cláudia Nunes, and Salette Reis. "Licofelone-DPPC Interactions: Putting Membrane Lipids on the Radar of Drug Development." Molecules 24, no. 3 (2019): 516. http://dx.doi.org/10.3390/molecules24030516.

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(1) Background: Membrane lipids have been disregarded in drug development throughout the years. Recently, they gained attention in drug design as targets, but they are still disregarded in the latter stages. Thus, this study aims to highlight the relevance of considering membrane lipids in the preclinical phase of drug development. (2) Methods: The interactions of a drug candidate for clinical use (licofelone) with a membrane model system made of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) were evaluated by combining Langmuir isotherms, Brewster angle microscopy (BAM), polarization-modu
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8

Mituła, Paweł, Czesław Wawrzeńczyk, and Witold Gładkowski. "Comparative Studies on the Susceptibility of (R)-2,3-Dipalmitoyloxypropylphosphonocholine (DPPnC) and Its Phospholipid Analogues to the Hydrolysis or Ethanolysis Catalyzed by Selected Lipases and Phospholipases." Catalysts 11, no. 1 (2021): 129. http://dx.doi.org/10.3390/catal11010129.

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Susceptibility of soybean phosphatidylcholine, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and its phosphono analogue (R)-2,3-dipalmitoyloxypropylphosphonocholine (DPPnC) towards selected lipases and phospholipases was compared. The ethanolysis of substrates at sn-1 position was carried out by lipase from Mucor miehei (Lipozyme®) and lipase B from Candida antarctica (Novozym 435) in 95% ethanol at 30 °C, and the hydrolysis with LecitaseTM Ultra was carried out in hexane/water at 50 °C. Hydrolysis at sn-2 position was carried out in isooctane/Tris-HCl/AOT system at 40 °C using phospholip
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9

Kruszewska, Natalia, Krzysztof Domino, Radosław Drelich, Wiesław Urbaniak, and Aneta D. Petelska. "Interactions between Beta-2-Glycoprotein-1 and Phospholipid Bilayer—A Molecular Dynamic Study." Membranes 10, no. 12 (2020): 396. http://dx.doi.org/10.3390/membranes10120396.

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This study aims to investigate the interactions appearing when the beta-2-glycoprotein-1 binds to a lipid bilayer. The inter- and intra-molecular forces acting between the two macromolecular systems have been investigated using a molecular dynamics simulation method. The importance of water bridges has also been addressed. Additionally, the viscoelastic response of the bilayer has been studied. In detail, the (saturated-chain) 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and (unsaturated-chain) 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE) bilayers have been chosen to test
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10

Neunert, Grażyna, Jolanta Tomaszewska-Gras, Aneta Baj, Marlena Gauza-Włodarczyk, Stanislaw Witkowski, and Krzysztof Polewski. "Phase Transitions and Structural Changes in DPPC Liposomes Induced by a 1-Carba-Alpha-Tocopherol Analogue." Molecules 26, no. 10 (2021): 2851. http://dx.doi.org/10.3390/molecules26102851.

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Steady-state emission spectroscopy of 1-anilino-8- naphthalene sulfonate (ANS) and 1,6-diphenyl-1,3,5-hexatriene (DPH), fluorescence anisotropy, and DSC methods were used to characterize the interactions of the newly synthesized 1-carba-alpha-tocopherol (CT) with a 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) membrane. The DSC results showed significant perturbations in the DPPC structure for CT concentrations as low as 2 mol%. The main phase transition peak was broadened and shifted to lower temperatures in a concentration-dependent manner, and pretransition was abolished. Increasing CT
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11

Burilov, Vladimir, Ramilya Garipova, Elsa Sultanova, et al. "New Amphiphilic Imidazolium/Benzimidazolium Calix[4]arene Derivatives: Synthesis, Aggregation Behavior and Decoration of DPPC Vesicles for Suzuki Coupling in Aqueous Media." Nanomaterials 10, no. 6 (2020): 1143. http://dx.doi.org/10.3390/nano10061143.

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In this study, new types of amphiphilic calix[4]arene derivatives bearing N-alkyl/aryl imidazolium/benzimidazolium fragments were designed and synthesized by two step transformation: Regioselective Blanc chloromethylation of distal-di-O-butyl calix[4]arene and subsequent interaction with N-Substituted imidazole/benzimidazole. Critical aggregation concentration (CAC) values were estimated using pyrene fluorescent probe. Obtained macrocycles were found to form submicron particles with electrokinetic potential +44–+57 mV in aqueous solution. For the first time it was found that amphiphilic calixa
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12

Sinha, Ragini, Urmila J. Joshi, Akshada Joshi, and Girjesh Govil. "LOCALIZATION AND ORIENTATION OF METHOXY FLAVONOIDS IN DPPC BILAYERS: EFFECT ON THEIR ANTI-PROLIFERATIVE ACTIVITY." International Journal of Current Pharmaceutical Research 10, no. 2 (2018): 60. http://dx.doi.org/10.22159/ijcpr.2018v10i2.25872.

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Objective: Flavones and flavonols are an important class of naturally occurring flavonoids. They are well known for their pharmacological activity. This activity is associated with the ability of flavones and flavonols to influence membrane–dependent processes. In this paper, we have reported localization, orientation and interaction, of four synthesized flavone/flavonols with 1, 2–dipalmitoyl–sn–glycero–3–phosphocholine (DPPC) bilayers. These are compared with standard flavone; chrysin (CHY) and flavonol Quercetin (QUE).Methods: The molecules studied are 4ʹ–methoxy flavone (MF), 3ʹ,4ʹ–dimetho
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13

PALMBLAD, Marie, Jan JOHANSSON, Bengt ROBERTSON, and Tore CURSTEDT. "Biophysical activity of an artificial surfactant containing an analogue of surfactant protein (SP)-C and native SP-B." Biochemical Journal 339, no. 2 (1999): 381–86. http://dx.doi.org/10.1042/bj3390381.

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Natural surfactant preparations containing phospholipids and the hydrophobic surfactant proteins B and C (SP-B and SP-C) are effective in the treatment of respiratory distress syndrome in premature infants. The limited supply, and the risk of infectious agents and immunological reactions have promoted the evaluation of synthetic peptides in surfactant preparations. However, the folding of synthetic SP-C into an α-helix is inefficient and α-helical SP-C analogues with Val → Leu substitutions form oligomers. In order to circumvent these problems we have synthesized an SP-C analogue, named SP-C(L
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14

Piosik, Emilia, Marta Ziegler-Borowska, Dorota Chełminiak-Dudkiewicz, and Tomasz Martyński. "Effect of Aminated Chitosan-Coated Fe3O4 Nanoparticles with Applicational Potential in Nanomedicine on DPPG, DSPC, and POPC Langmuir Monolayers as Cell Membrane Models." International Journal of Molecular Sciences 22, no. 5 (2021): 2467. http://dx.doi.org/10.3390/ijms22052467.

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An adsorption process of magnetite nanoparticles functionalized with aminated chitosan (Fe3O4-AChit) showing application potential in nanomedicine into cell membrane models was studied. The cell membrane models were formed using a Langmuir technique from three selected phospholipids with different polar head-groups as well as length and carbon saturation of alkyl chains. The research presented in this work reveals the existence of membrane model composition-dependent regulation of phospholipid-nanoparticle interactions. The influence of the positively charged Fe3O4-AChit nanoparticles on a Lan
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15

McCullough, Casey, Matthew Heywood, and Hussein Samha. "Aggregation of Cyanine Dye in Bilayer Vesicles of Phospholipids." Volume 4, Issue 3 4, no. 3 (2005). http://dx.doi.org/10.33697/ajur.2005.020.

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The effect of phospholipid, 1,2-Dipalmitoyl-sn-glycero-3-Phosphocholine (DPPC) on the spectroscopy of the cyanine dye, 1-ethyl-1’-octadecyl-2,2’-cyanine iodide (PIC-18), has been investigated using UV-Vis spectroscopy. Vesicles of DPPC containing PIC-18 in the molar ratio of 1:3 (dye/phospholipids) were prepared in aqueous solution. J-aggregates of PIC-18 were detected in the bilayer wall of the vesicles. When an aqueous solution of mixed PIC-18/DPPC vesicles is treated with excess DPPC vesicles that are prepared separately, the dye molecules in the mixed vesicles underwent a rapid (aggregate)
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16

Bouarab, Lynda, Pascal Degraeve, Jalloul Bouajila, et al. "Staphylococcus aureus membrane-damaging activities of four phenolics." FEMS Microbiology Letters 368, no. 13 (2021). http://dx.doi.org/10.1093/femsle/fnab081.

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Abstract The membrane-damaging activities of four phenolics chosen for their bactericidal activity against Staphylococcus aureus CNRZ3 were investigated: 5,7-dihydroxy-4-phenylcoumarin (DHPC), 5,8-dihydroxy-1,4-naphthoquinone (DHNQ), epigallocatechin gallate (EGCG) and isobutyl 4-hydroxybenzoate (IBHB). Staphylococcus aureus CNRZ3 cells, as well as model liposomes mimicking its membrane phospholipids composition, were treated with each phenolic at its minimal bactericidal concentration. Membrane integrity, intracellular pH and intracellular esterase activity were examined by flow cytometric an
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