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Journal articles on the topic "1-960"

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Åsbrink, S., L. Kihlborg, and M. Malinowski. "High-pressure single-crystal X-ray diffraction studies of MoO3. I. Lattice parameters up to 7.4 GPa. Erratum." Journal of Applied Crystallography 22, no. 4 (1989): 380. http://dx.doi.org/10.1107/s0021889889002220.

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Owing to a printer's error, the fourth equation given in the Abstract of the paper by Åsbrink, Kihlborg & Malinowski [J. Appl. Cryst. (1988). 21, 960–962] is incorrect. The correct equation is {\bar \beta}_c(0–7.41 GPa) = −3.35 × 10−4 (GPa)−1.
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Marchi, Sidnei Roberto, Daniel Bogorni, Leandro Biazzi, and José Ricardo Bellé. "Associações entre glifosato e herbicidas pós-emergentes para o controle de trapoeraba em soja RR®." Revista Brasileira de Herbicidas 12, no. 1 (2013): 23. http://dx.doi.org/10.7824/rbh.v12i1.173.

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Este trabalho teve o objetivo de avaliar a seletividade e a eficácia da associação do glifosato com herbicidas pós-emergentes no controle de trapoeraba na cultura da soja Roundup Ready®. Para tanto, o experimento foi instalado no delineamento de blocos ao caso, com quatro repetições, onde os tratamentos foram constituídos de quatro doses do herbicida cloransulam-metil (10, 20, 30 e 40 g ha-1), quatro doses do herbicida clorimurom-etílico (2,5, 5,0, 7,5 e 10,0 g ha-1), imazetapir a 100 g ha-1 e lactofen a 72 g ha-1, todos estes utilizados em associação com o herbicida glifosato a 960 g ha-1. Também foram incluídas três testemunhas, sendo aplicação única do herbicida glifosato a 960 g ha-1, aplicação sequencial do glifosato a 960/ 960 g ha-1 e testemunha geral sem capina. Os resultados demonstraram que apenas a aplicação única do herbicida glifosato a 960 g ha-1 e sua associação com as menores doses de cloransulam-metil (10 g ha-1) e clorimurom-etílico (2,5 g ha-1) não proporcionaram controle efetivo da trapoeraba. Todos os tratamentos herbicidas não influenciaram na produtividade da soja RR®, embora a associação do glifosato com a maior dose de clorimurom-etílico (10 g ha-1) tenha proporcionado redução significativa no peso de 1000 grãos de soja.
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Minozzi, Guilherme Barbosa, Pedro Jacob Christoffoleti, Patricia Andrea Monquero, Luiz Henrique Saes Zobiole, Gabriel Roher Pereira, and Lucas Duck. "Controle em pré semeadura da cultura de soja de algodão voluntário tolerante ao glyphosate e amônio glufosinate e de Eleusine indica." Revista Brasileira de Herbicidas 16, no. 3 (2017): 183. http://dx.doi.org/10.7824/rbh.v16i3.547.

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O objetivo do trabalho foi avaliar a eficácia de herbicidas aplicados em pré-emergência, em diferentes doses e épocas, antes da semeadura de soja sob condição de déficit hídrico, para o controle de plantas voluntárias de algodão, tolerante aos herbicidas glyphosate e amônio glufosinate, e Eleusine indica. O ensaio foi conduzido no município de Formosa do Rio Preto/BA, durante a safra 2015/16, utilizando o delineamento experimental de blocos ao acaso, com quatro repetições e dez tratamentos, sendo: glyphosate + diclosulam (960 + 25,2 g ha-1 e.a./i.a.) e glyphosate + diclosulam (960 + 35 g ha-1 e.a./i.a.), aplicados aos 50, 20 e 0 dias antes da semeadura (DAS), glyphosate + flumioxazin (960 + 50 g ha-1 e.a./i.a.), glyphosate + sulfentrazone (960 + 150 g ha-1 e.a./i.a.) e glyphosate + sulfentrazone (960 + 200 g ha-1 e.a./i.a.) aplicados 0 DAS, além de um tratamento controle. Avaliações visuais de controle foram efetuadas aos 7 e 0 DAS, aos 14 e 45 dias depois da semeadura (DDS) e a produtividade da soja estimada. A aplicação do herbicida diclosulam é eficaz no controle de algodão voluntário, quando aplicado 50, 20 e 0 DAS, nas doses de 25,2 e 35 g ha-1 i.a. O tratamento sulfentrazone é eficaz, quando aplicado 0 DAS nas doses de 150 e 200 g ha-1 i.a., enquanto o herbicida flumioxazin não é eficaz. No controle de Eleusine indica o diclosulam foi o melhor tratamento quando aplicado 0 DAS a 25,2 e 35 g ha-1 i.a. A produtividade foi considerada igual entre tratamentos.
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Lacerda, André Luiz De Souza, Sandro Roberto Brancalião, and Nádia Regina Rodrigues. "Resíduos de glyphosate e aminometilfosfônico (ampa) em soja geneticamente modificada." Revista Brasileira de Herbicidas 15, no. 3 (2016): 263. http://dx.doi.org/10.7824/rbh.v15i3.468.

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Aplicações indiscriminadas e sucessivas podem ocasionar casos de intoxicação nos seres humanos por ingestão indireta de glyphosate devido ao fato dos grãos de soja transgênica apresentarem níveis de resíduos desse herbicida acima do permitido. Objetivou-se com este trabalho avaliar os níveis de resíduos de glyphosate e ácido aminometilfosfônico (AMPA) nos grãos de soja geneticamente modificada tolerante ao glyphosate. O delineamento experimental utilizado foi em blocos casualizados com 8 tratamentos e 4 repetições. Os tratamentos foram constituídos por glyphosate, aplicados uma única vez e isoladamente nas dosagens de 720 e 960 g.i.a ha-1, glyphosate a 720 e 960 g.i.a ha-1 em mistura, respectivamente, com chlorimuron-ethil a 10 g.i.a ha-1, aplicações sequênciais de glyphosate nas dosagens de 720/720; 960/720; 960/720/720 g.i.a ha-1 e testemunha capinada durante todo o ciclo da cultura. As amostras foram analisadas por cromatografia líquida de alta eficiência (CLAE). As características avaliadas foram os níveis de resíduos (mg kg-1) de glyphosate e do seu metabólito AMPA. O nível máximo de resíduo de glyphosate encontrado nos grãos de soja foi de 0,92 mg kg-1, estando abaixo do permitido que é de 10,00 mg kg-1. Também foram encontrados resíduos de AMPA, máximo de 1,53 mg kg-1, indicando que houve metabolização do glyphosate.
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Ayegboyin Kayode Olufemi, Adejobi Kayode Babatunde, Olaniyi Olayinka Olufemi, et al. "Evaluation of herbicides and manual weed control methods in the establishment of Theobroma cacao L. in Cross River State of Nigeria." World Journal of Advanced Research and Reviews 8, no. 1 (2020): 298–306. http://dx.doi.org/10.30574/wjarr.2020.8.1.0368.

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Field trial was conducted at the Cocoa Research Institute of Nigeria (CRIN), Ajassor substation, Cross River State, Nigeria between 2015 and 2017 to evaluate the effect of different weed control methods on the growth and yield of cocoa during their early years of establishment. Glyphosate and paraquat were applied at 480, 720, 960 and 1440 gram of active ingredient per hectare using very low volume (g a.i. ha-1 vlv) while manual weeding (i.e. slashing with cutlass) was used as the control. A Nigeria commercial cocoa variety Tc series, also known as 18-month cocoa, was established at a CRIN recommended spacing of 3 x 3 m, laid out in a Complete Randomized Block Design with four replications. All young cocoa stands were ring weeded at 50 cm diameter and covered with black polythene bags before the spraying of herbicides during the first six months of establishment to reduce injury that could result from the drifting of herbicide solution to plants during their early growth stage. Data was collected on the plant height, stem girth and number of leaves of cocoa plants while the cocoa dry beans weight and labour cost for each treatment were determined. The results showed that 960 g a.i. ha-1 vlv was the best herbicide application rate while plots under glyphosate at 960 g a.i. ha-1 vlv produced significantly higher values of plant height, stem girth and number of leaves at (p=0.05) than both paraquat at 960 g a.i. ha-1 vlv and manual weeding. Labour cost for controlling weeds with either glyphosate or paraquat at all application rates were considerably lower than cost for control (manual weeding). Glyphosate at 960 g a.i. ha-1 vlv is recommended for weed control in cocoa plantation because it encouraged higher growth and yield performance of cocoa than other treatments, had considerably cheaper cost of application than paraquat at 960 g a.i. ha-1 vlv and manual weeding, and it also ensured a weed-free environment over a longer period of time than the other treatments.
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NOGUEIRA, C. H. P., and N. M. CORREIA. "Selectivity of Herbicides Bentazon and Nicosulfuron for Crotalaria juncea Intercropped with Maize Culture." Planta Daninha 34, no. 4 (2016): 747–58. http://dx.doi.org/10.1590/s0100-83582016340400015.

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ABSTRACT The objective was to study the selectivity of herbicides bentazon and nicosulfuron, alone and in a mixture, to Crotalaria juncea, when established in intercropping with maize, as well as weed control and maize development in this production system. Two experiments were conducted in the field, in late harvest and in harvest periods. The experimental design was a randomized block, with 14 treatments and four replicates. Eight treatments with herbicides bentazon (720 and 960 g a.i. ha-1), nicosulfuron (16 and 48 g a.i. ha-1) and bentazon plus nicosulfuron (720 + 16; 720 + 48; 960 + 16; 960 + 48 g a.i. ha-1) were studied, besides six controls (single crop maize and sunn hemp, with and without weed control, intercropped maize and sunn hemp, with and without weed control). Herbicide bentazon alone, in both dosages evaluated, was selective to C. juncea. Nicosulfuron in the dosage of 48 g a.i. ha-1, alone or in a mixture with bentazon, promoted the best weed control. Maize interferes in the recoverability of sunn hemp plants treated with herbicides. C. juncea intercropped without herbicides or sprayed with bentazon negatively impacted maize yield in the harvest. The pulverization of bentazon (720 and 960 g a.i. ha-1) in late harvest and bentazon plus nicosulfuron (720 +16 and 920 + 16 g a.i. ha-1) in harvest provided the best results, considering maize yield, development and recovery of sunn hemp and weed management.
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Albrecht, L. P., D. G. Alonso, A. J. P. Albrecht, R. S. Oliveira JR., A. L. Braccini, and J. Constantin. "Glyphosate e associações em pós-emergência no desempenho agronômico e na qualidade das sementes de soja RR®." Planta Daninha 30, no. 1 (2012): 139–46. http://dx.doi.org/10.1590/s0100-83582012000100016.

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O presente trabalho objetivou avaliar os componentes de produção e a qualidade das sementes de soja RR® em função da aplicação, em pós-emergência, de glyphosate isolado e em mistura em tanque. Os experimentos de campo foram instalados no município de Mandaguari, Paraná, em duas safras. Os tratamentos testados (doses em g i.a. ha-1) foram compostos por glyphosate (960), glyphosate+fluazifop-p-butyl+fomesafen em duas diferentes combinações (960+187,5+187,5 e 960+312,5+312,5), glyphosate+bentazon (960+720), glyphosate+chlorimuron-ethyl (960+25), testemunha sem capina e testemunha capinada. As aplicações foram realizadas no momento em que a cultura se encontrava entre os estádios V4 e V5. O delineamento experimental utilizado foi em blocos casualizados com quatro repetições. As variáveis avaliadas foram produtividade, massa de mil sementes e, ainda, a qualidade das sementes. Os dados foram submetidos à análise de variância, e as médias, comparadas por meio do método de agrupamento de Scott-Knott. As misturas glyphosate+chlorimuron-ethyl e fluazifop-p-butyl+fomesafen comprometeram o desempenho agronômico do cultivar avaliado, sendo a mistura com chlorimuron-ethyl mais prejudicial. As associações possuem potencial de interferir negativamente na qualidade das sementes, especialmente no vigor.
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Silva, André Felipe Moreira, Ana Ligia Giraldeli, Felipe Carrara de Brito, et al. "Eficácia de herbicidas isolados e em associações no controle em pós‑emergência de plantas daninhas." Revista Brasileira de Herbicidas 17, no. 4 (2018): 576. http://dx.doi.org/10.7824/rbh.v17i2.576.

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É essencial a rotação de mecanismos de ação de herbicidas no manejo de plantas daninhas resistentes ao glyphosate, neste contexto o uso de herbicidas inibidores da enzima ALS em associação pode auxiliar no controle. O objetivo do trabalho foi avaliar a eficácia de sulfometuron, chlorimuron e outras sulfonilureias, isolados ou em associação com glyphosate, no controle de amendoim-bravo, corda-de-viola e picão-preto. Foram realizados três experimentos em casa-de-vegetação, em delineamento inteiramente casualizado, com quatro repetições. Os tratamentos corresponderam aos herbicidas aplicados em pós-emergência das plantas daninhas mais a testemunha (sem aplicação), quando estas estavam com duas folhas completamente desenvolvidas. Os resultados evidenciaram que sulfometuron (15 g ha-1 i.a.) + chlorimuron (20 g ha-1 i.a.) + glyphosate (960 g ha-1 e.a.), foi eficaz no controle de amendoim-bravo, e o tratamento halosulfuron (80 g ha-1 i.a.) + glyphosate (960 g ha-1 e.a.) propiciou controle de 76,25%. A aplicação de sulfometuron (15 g ha-1 i.a.) + chlorimuron (20 g ha-1 i.a.) + glyphosate (960 g ha-1 e.a.), foi eficaz no controle de corda-de-viola. Todos os tratamentos herbicidas foram eficazes no controle em pós-emergência de picão-preto.
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Rocha, D. C., R. A. Rodella, D. Martins, and C. D. G. Maciel. "Efeito de herbicidas sobre quatro espécies de trapoeraba." Planta Daninha 25, no. 2 (2007): 359–64. http://dx.doi.org/10.1590/s0100-83582007000200016.

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O controle químico de espécies do gênero Commelina (trapoerabas) é, muitas vezes, insatisfatório, apesar do uso intenso de herbicidas. O presente trabalho teve como objetivo avaliar o controle de quatro espécies daninhas de Commelina com o uso de diferentes herbicidas aplicados em pós-emergência. Foram avaliadas plantas de C. benghalensis, C. villosa, C. diffusa e C. erecta, em estádio com mais de quatro folhas e caules com cerca de 15 a 25 cm de comprimento, submetidas aos tratamentos com carfentrazone-ethyl (30 e 50 g ha-1), glyphosate (960 g ha-1), carfentrazone-ethyl + glyphosate (30 + 960 g ha-1) e sulfentrazone + glyphosate (150 + 960 g ha-1), além de uma testemunha sem aplicação. O delineamento experimental foi inteiramente casualizado, com quatro repetições. Verificou-se que o controle químico de trapoerabas foi dependente da espécie, sendo C. benghalensis controlada mais eficientemente com os tratamentos testados, enquanto C. erecta apresentou o menor controle. A aplicação de glyphosate em mistura com carfentrazone-ethyl foi mais eficiente no controle das espécies de trapoeraba do que os demais tratamentos empregados.
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Tilg, Herbert, and Alexander R. Moschen. "Corrigendum to “IL-1 cytokine family members and NAFLD: Neglected in metabolic liver inflammation” [J Hepatol 2011;55:960–962]." Journal of Hepatology 56, no. 3 (2012): 748. http://dx.doi.org/10.1016/j.jhep.2011.10.010.

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Dissertations / Theses on the topic "1-960"

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Dancila, Bogdan Dumitru. "Altitude optimization algorithm for cruise, constant speed and level flight segments." Mémoire, École de technologie supérieure, 2011. http://espace.etsmtl.ca/960/1/DANCILA_Bogdan_Dumitru.pdf.

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Dans ce mémoire le développement d’un algorithme est présenté. Dans cet algorithme, nous déterminons l’altitude optimale pour un vol de croisière, à une vitesse et altitude constantes, sur un segment donné de la trajectoire de vol. Le critère d’optimisation correspond à la minimisation des couts totaux, et, si possible, de la consommation de combustible, pour parcourir le segment de croisière spécifié. Le but principal est de prouver le concept d’un algorithme, pour une fonctionnalité du FMS, informant les pilotes sur l’altitude de vol optimale pour le segment de croisière considéré. L’algorithme a été développé en MATLAB, en utilisant une nouvelle méthode de calcul de la consommation de combustible pour les vols de croisière, à une vitesse et altitude constantes, en utilisant les données de performance de l’avion. Trois modèles d’avion ont été considérées, un pour lequel le modèle du vol de croisière prend en compte la position du centre de gravité, et deux modèles qui ne le font pas. L’algorithme a été développé pour des conditions normales de vol, et il ne prend pas en compte les couts correspondent aux changements d’altitude, au début et à la fin du segment, requises pour atteindre l’altitude optimale et revenir à l’altitude de croisière initiale. Les performances de l’algorithme ont été évaluées sur trois modèles d’avion – Airbus A310, Sukhoi RRJ et Lockheed L1011. Les données de validation ont été générées à partir des informations produites sur une plate-forme FMS de CMC Electronics – Esterline, qui utilise les mêmes modèles d’avion, et les mêmes données de performance, pour les mêmes conditions de vol
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Chefer, Sonia Mara. "Os jogos educativos como ferramenta de aprendizagem enfatizando a educação ambiental no ensino de ciências." Universidade Tecnológica Federal do Paraná, 2014. http://repositorio.utfpr.edu.br/jspui/handle/1/960.

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Esta pesquisa tem como objetivo analisar os jogos educativos como proposta de prática investigativa, bem como avaliar a aprendizagem por meio desse instrumento no Ensino de Ciências, sobre o tema transversal Meio Ambiente, enfatizando a Educação Ambiental no Ensino Fundamental. Evidencia a Educação Ambiental, considerando a aprendizagem significativa, com destaque específico para a utilização de jogos educativos. Discute o Ensino de Ciências no Brasil, a Educação Ambiental, os Jogos Educativos, a Aprendizagem Significativa, com base na literatura pertinente ao tema. A pesquisa abrange uma população de 65 alunos. Para a coleta dos dados utilizou-se de questionários com questões abertas e fechadas para levantamento dos conhecimentos prévios dos alunos (pré-teste) e pós-teste. Apresenta resultados sobre a utilização de jogos didáticos no encaminhamento metodológico, de forma significativa no processo de ensino aprendizagem de Ciências e que facilitem a compreensão do conteúdo de forma motivadora e divertida. Demonstra que o jogo educativo constitui-se em um importante auxílio para o trabalho curricular por seu caráter motivacional, desafiador e construtivo; pode ser inserido no planejamento disciplinar e utilizado como proposta pedagógica, pois possibilitou um ambiente educativo e descontraído com evidências de aprendizagem significativa. A proposta da utilização dos jogos educativos no ensino de Ciências e Educação Ambiental se formaliza a partir da constatação das características lúdicas de ensino que o material produzido possui. Dessa maneira, podem proporcionar ao professor um recurso que possibilita chamar a atenção do aluno, aguçando a curiosidade em buscar novos conhecimentos sobre o ambiente em que vive. Como produto final desta pesquisa, estruturou-se uma Unidade Didática, com um conjunto ordenado de atividades, estruturadas e articuladas, visando auxiliar o professor de Ciências em sua ação pedagógica durante o ano letivo.<br>This research aims to analyze the educational games as a proposed research practice, and assess learning through this instrument in Science Teaching, on the cross-cutting theme Environment, emphasizing the Environmental Education in Elementary Education. Evidence Environmental Education, considering the significant learning, with specific emphasis on the use of educational games. Discusses the teaching of science in Brazil, Environmental Education, the Educational Games, Meaningful Learning, based on the literature relevant to the topic. The research covers a population of 65 students. To collect the data we used questionnaires with open and closed questions for survey of students' prior knowledge (pretest) and posttest. Presents results on the use of educational games in methodological routing significantly in the teaching and learning of Science to facilitate understanding of the content in a motivating and fun way. Demonstrates that the educational game constitutes an important aid for curriculum work for his motivational, challenging and constructive character; can be inserted in the disciplinary planning and used as a pedagogical proposal, it enabled a substantial and relaxed environment with evidence of significant learning. The proposed use of educational games in teaching Science and Environmental Education is formalized based on the findings of the entertaining features of teaching that has produced the material. Thus, the teacher can provide a resource that enables call the student's attention, sharpening the curiosity to seek new knowledge about the environment in which he lives. As a final product of this research, structured on a Didactic Unit, with an ordered set of activities, structured and articulated, aiming to help the science teacher in their pedagogical activities during the school year.
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Cinici, Ahmet. "An Architectural Investigation Of Leisure Spaces In The Roman Domestic Context: The Case Of Ephesus." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607673/index.pdf.

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Leisure is most basically defined as the time free from work. The ancient conception and forms of leisure were quite different from the modern ones, which came into discussion during the industrial era. The Roman society was highly stratified and comprised of diverse social classes for which leisure acquired different forms and meanings. Every stratum of the Roman society enjoyed the possibilities and pleasures of leisure proportional to its hierarchy in the social system, so that leisure can be investigated in both public and private contexts in the Roman world. This study aims to investigate leisure, which was one of the main driving social forces in the Roman society, in spatial terms with reference to Roman domestic architecture. The study focuses on central Italy and particularly on Ephesus, the latter of which is a good example to discuss how the Roman conception of leisure was spatially materialized in a provincial private setting since a group of well studied, documented, and published houses constitute an appropriate comparative sample and context in Ephesus. The spatial organization and characteristics of the spaces housing leisurely activities are discussed on the basis of an axes-scheme that regulated and even dictated the visual and bodily interaction of the participants with certain spaces and elements during leisure activities either in a static state (sitting, reclining), or a kinetic one (walking, perambulating). The visual axes are those perceived in either of these states, along which the eye is directed towards a visual focal point, whereas the dynamic axes are those along which people move during a kinetic leisurely activity. The location, architecture, and use of leisure-oriented spaces in the Roman period houses in Ephesus, such as triclinium, exedra, oecus, museion, and peristyle courtyard are examined with reference to the proposed axes-scheme to present and compare the operation of leisure in the Roman provincial and private setting.
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Ozarslan, Yasemin. "The Cultic Landscapes Of Phrygia." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12612840/index.pdf.

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This thesis examines Phrygian cultic sites in Western Phrygia from the perspective of landscape using a range of Geographical Information Systems (GIS) analyses. More specifically, it explores spatial relationships between these cultic sites and the regional geographical context with reference to certain environmental and cultural parameters. These include topography, geology, and distance to settlements, hilltop sites, and ancient roads. A total of 30 Phrygian cultic sites form the primary archaeological evidence. Secondary archaeological evidence covers a range of mound settlements and hilltop sites associated with Phrygian culture. The study heavily relies on the readily available archaeological site data from related publications and recent surveys in the region. Geographic datasets used include ASTER Global DEM and derived surfaces, as well as digital geological and historical maps. This study contributes to our understanding of Phrygian cultic sites by revealing certain patterns as to their locations. It also brings all the available site data from Western Phrygia together for the first time. Ultimately, it suggests that the &ldquo<br>highlandscapes&rdquo<br>of Phrygia with spectacular geological formations could have played a crucial role on the cultic site locations.
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Ulusoy, Derya. "Archaeology Of The Galatians At Ancyra From The Hellenistic Period Through The Roman Era." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607385/index.pdf.

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Galatians who entered into Anatolia in about 280 B.C., in order to help the Bithynian king Nicomedes I against his brother Zipoetas, had a significant role in the history of the ancient Asia Minor. Archaeological material that were recovered from different sites such as Gordion, Pessinus and Tavion and fort settlements mostly dating to the late Hellenistic Period are the most important sources that provide information on their presence in Galatia region named after them. The main purpose of this thesis is to bring together all the archaeological, historical and epigraphical data to present in a coherent way and examine the fort settlements around Ancyra attributed to the Galatians. It both aims to understand the Galatians archaeologically and also by applying new methods such as Visibility Analysis through GIS studies, it hopes to materialize some of the assumptions regarding settlement systems. In order to achieve these, after a thorough presentation of the archaeological and historical data, the forts surveyed around Ancyra are described individually and then studied as a system with the help of Visibility Analysis. The thesis also confirms the presumed relationship between the location of the forts and the topography as well as identifying criteria for choice of location for ancient settlements.
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Uncu, Hakki. "Carbon-14 Chronology Of Anatolia In Early Bronze Age." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12612845/index.pdf.

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This study is a conclusion of radiocarbon datings which are depend on evaluations of archaeologists or scholars who publishes these datings. So it is very attached to observations of those scholars especially for determining sub-phases of samples which are dated. According to these datings, the radiocarbon story of Anatolian Early Bronze Age starts with a dating from Troia from 3760 cal. BC and ends with a dating from &Ccedil<br>adirh&ouml<br>y&uuml<br>k in 1630 cal. BC. Of course these dates are the lower and higher borders of the 68% probability band. As a result of assessments of all datings it can be said that the beginning of Early Broze Age in Anatolia is started equally more or less in every region at the same time interval that corresponds 3700/3400 BC and continued 800 years approximately. Although error deviation bands overlap onto each other, it is possible to say that the EB2 period of Anatolia ruled between 2800-2400 BC roughly. In this work it can be observed that the ending of the Early Bronze Age in Anatolia generally not ocured simultaneously. Sos H&ouml<br>y&uuml<br>k for example in the East Anatolia for example, drawing a very special profile with an ending date 2300 BC for the Early Bronze Age. Some other sites giving results as late as nearly in 18th. and 17th. century BC. For the timing of the end of Early Bronze Age in Anatolia, it can be said that, inequality among the sites are more likely other than regions.
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Sakarya, Ilham. "Defining Spatial Distribution Of Storage Vessels In Ancient Burgaz At The Fourth Century B.c." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/1253244/index.pdf.

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This research is an investigation of the spatial organization of household activities and especially the storage facilities in Ancient Burgaz. The four well-preserved houses at the Northeast Sector, their artefact assemblages which come from the final occupation floor level dated to the 4th century B.C., and the storage containers have been evaluated. The spatial distributions of the artefacts were studied through the use of quantitative methods with the objective of identifying storage spaces in Burgaz houses. The results of this quantitative analysis and the observations regarding Burgaz houses have been compared to other contemporary sites in ancient Aegean.
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Sentek, Mina. "Cult Buildings In Aceramic Neolithic Southeast Anatolia: A Case Study Of Nevali Cori." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607137/index.pdf.

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First settlements in Southeast Anatolia begun to appear as early as 10000 BC. Among all the unanswered questions about this early period, cult-related activities and cult buildings are widely studied due to their nature, which has strong connections with the social organization and early symbolism. During the last decade, Southeast Anatolia has provided new evidence for this early stage of development in human history. This study aims to examine cult buildings that have common characteristics<br>how they were treated and distributed. The settlement of Nevali &Ccedil<br>ori and its cult building is taken as an example and studied in detail. Other cult buildings with the same or similar architectural features are included in this study in order to discuss the roots, the distribution and the continuity of this Aceramic Neolithic tradition.
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Tuncer, Aylin. "Deposition And Dislocation Of Pottery As Surface Assemblages In Semi-arid Regions." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12605927/index.pdf.

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This thesis aims to discuss the archaeological concerns about how surveys can provide data tht is meaningful to construct spatial patterning and its intricacies for inferences through altering processes diversified as cultural and natural processes. Along with that there is also a second concern dealing with the application of these theoretical issues to practical basis. It consists both methodological limits and also limits governed by the legislation of the particular area according to the aim of the study. A particular space, semi-arid climate is selected for comparing the amount of attrition and accretion caused by natural factors, to be able to apply the studies to Anatolian geography. However applications from around the world are frequently discussed here, these are mainly the case studies bringing methodological scheme for the appropriate data collection.
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Atici, Nadire. "Defining Cooking Activity Areas Of Burgaz Domestic Units In The 4th Century B.c." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/1253251/index.pdf.

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The main aim of this study is to define the cooking activity spaces in Burgaz at 4th Century B.C. by carrying out statistical analysis of artefacts come from floor levels. In this study the distribution of artefacts and the associations of these distributions with architectural remains are examined rather than architectural features. In order to defining cooking activity spaces, the spatial distribution of cooking wares and utilities were taken into consideration. The distributions of cooking wares were tried to associate with ashy areas that can be related to cooking activities. In this study, the spatial analysis of archaeological artefacts assemblages that found in four well preserved houses from NE Sector revealed during the excavations of Burgaz (1993-2003) was carried out and the space usage, especially cooking spaces, were identified in these houses.
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Books on the topic "1-960"

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Θεοδοσίου, Νίκος. Κινηματογραφικά μηχανήματα made in Greece. Μουσείο κινηματογράφου Θεσσαλονίκης, 2009.

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Kofou, Anna. Kreta. Ekdotike Athenon S.A., 1990.

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Калас, Н. [Шлях Нікіти Ранту. Ікарос, 1997.

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Дракондаїдіс, Ф. [Послання. Естія, 1990.

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Алексакіс, В. [Раніше. Ександас, 1994.

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Баколас, Н. [Міфологія. Паратирітис, 1989.

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Jests, Dilip V., and Joseph H. Friedman, eds. Psychiatry for Neurologists. Humana Press, 2006. http://dx.doi.org/10.1007/978-1-59259-960-8.

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Kelly, John F., and William L. White, eds. Addiction Recovery Management. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-60327-960-4.

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Gimble, Jeffrey M., and Bruce A. Bunnell, eds. Adipose-Derived Stem Cells. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61737-960-4.

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Fanfani, David, and Claudio Fagarazzi, eds. Territori ad alta energia. Firenze University Press, 2012. http://dx.doi.org/10.36253/978-88-8453-960-1.

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In recent years the subject of energy planning has come to occupy a role of growing importance, both in relation to the escalating costs, scarcity and impact of energy procurement and consumption and in relation to the increasingly broad future prospects generated by the development of technologies for the exploitation of renewable sources. Within this framework, the development and use of the latter frequently appears to be without benchmarks for integration into the broader picture of territorial planning, and hence of coordination with other human activities and territorial resources. With this in mind, this book aims to compose the elements of a perspective in which energy planning is seen not as an ulterior and separate form of planning, but as an activity integrated within the more general instruments for the government of the territory, and more specifically one that employs the resources of the territory in a sustainable manner also with a view to endogenous local development.
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Book chapters on the topic "1-960"

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"1. The Expansion of the Piast Realm, 960–1100." In Europa Sacra. Brepols Publishers, 2014. http://dx.doi.org/10.1484/m.es-eb.4.00083.

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Messaoud, Riadh Ben, Sabine Loudcher Rabaséda, Rokia Missaoui, and Omar Boussaid. "OLEMAR." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch001.

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Data warehouses and OLAP (online analytical processing) provide tools to explore and navigate through data cubes in order to extract interesting information under different perspectives and levels of granularity. Nevertheless, OLAP techniques do not allow the identification of relationships, groupings, or exceptions that could hold in a data cube. To that end, we propose to enrich OLAP techniques with data mining facilities to benefit from the capabilities they offer. In this chapter, we propose an online environment for mining association rules in data cubes. Our environment called OLEMAR (online environment for mining association rules), is designed to extract associations from multidimensional data. It allows the extraction of inter-dimensional association rules from data cubes according to a sum-based aggregate measure, a more general indicator than aggregate values provided by the traditional COUNT measure. In our approach, OLAP users are able to drive a mining process guided by a meta-rule, which meets their analysis objectives. In addition, the environment is based on a formalization, which exploits aggregate measures to revisit the definition of the support and the confidence of discovered rules. This formalization also helps evaluate the interestingness of association rules according to two additional quality measures: lift and loevinger. Furthermore, in order to focus on the discovered associations and validate them, we provide a visual representation based on the graphic semiology principles. Such a representation consists in a graphic encoding of frequent patterns and association rules in the same multidimensional space as the one associated with the mined data cube. We have developed our approach as a component in a general online analysis platform called Miningcubes according to an Apriori-like algorithm, which helps extract inter-dimensional association rules directly from materialized multidimensional structures of data. In order to illustrate the effectiveness and the efficiency of our proposal, we analyze a real-life case study about breast cancer data and conduct performance experimentation of the mining process.
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Koh, Yun Sing, Richard O’Keefe, and Nathan Rountree. "Interestingness Measures for Association Rules." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch002.

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Association rules are patterns that offer useful information on dependencies that exist between the sets of items. Current association rule mining techniques such as apriori often extract a very large number of rules. To make sense of these rules we need to order or group the rules in some fashion such that the useful patterns are highlighted. The study of this process involves the investigation of an “interestingness” in the rules. To date, various measures have been proposed but unfortunately, these measures present inconsistent information about the interestingness of a rule. In this chapter, we show that different metrics try to capture different dependencies among variables. Each measure has its own selection bias that justifies the rationale for preferring it compared to other measures. We present an experimental study of the behaviour of the interestingness measures such as lift, rule interest, Laplace, and information gain. Our experimental results verify that many of these measures are very similar in nature. From the findings, we introduce a classification of the current interestingness measures.
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Ding, Qin, and Gnanasekaran Sundarraj. "Mining Association Rules from XML Data." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch003.

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With the growing usage of XML in the World Wide Web and elsewhere as a standard for the exchange of data and to represent semi-structured data, there is an imminent need for tools and techniques to perform data mining on XML documents and XML repositories. In this chapter, we propose a framework for association rule mining on XML data. We present a Java-based implementation of the Apriori and the FP-Growth algorithms for this task and compare their performances. We also compare the performance of our implementation with an XQuery-based implementation.
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Lee, Yue-Shi, and Show-Jane Yen. "A Lattice-Based Framework for Interactively and Incrementally Mining Web Traversal Patterns." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch004.

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Web mining is one of the mining technologies, which applies data mining techniques in large amount of web data to improve the web services. Web traversal pattern mining discovers most of the users’ access patterns from web logs. This information can provide the navigation suggestions for web users such that appropriate actions can be adopted. However, the web data will grow rapidly in the short time, and some of the web data may be antiquated. The user behaviors may be changed when the new web data is inserted into and the old web data is deleted from web logs. Besides, it is considerably difficult to select a perfect minimum support threshold during the mining process to find the interesting rules. Even though the experienced experts, they also cannot determine the appropriate minimum support. Thus, we must constantly adjust the minimum support until the satisfactory mining results can be found. The essences of incremental or interactive data mining are that we can use the previous mining results to reduce the unnecessary processes when the minimum support is changed or web logs are updated. In this paper, we propose efficient incremental and interactive data mining algorithms to discover web traversal patterns and make the mining results to satisfy the users’ requirements. The experimental results show that our algorithms are more efficient than the other approaches.
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Tushar, Tushar, Shibendu Shekhar Roy, and Dilip Kumar Pratihar. "Determination of Optimal Clusters Using a Genetic Algorithm." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch005.

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Clustering is a potential tool of data mining. A clustering method analyzes the pattern of a data set and groups the data into several clusters based on the similarity among themselves. Clusters may be either crisp or fuzzy in nature. The present chapter deals with clustering of some data sets using Fuzzy C-Means (FCM) algorithm and Entropy-based Fuzzy Clustering (EFC) algorithm. In FCM algorithm, the nature and quality of clusters depend on the pre-defined number of clusters, level of cluster fuzziness and a threshold value utilized for obtaining the number of outliers (if any). On the other hand, the quality of clusters obtained by the EFC algorithm is dependent on a constant used to establish the relationship between the distance and similarity of two data points, a threshold value of similarity and another threshold value used for determining the number of outliers. The clusters should ideally be distinct and at the same time compact in nature. Moreover, the number of outliers should be as minimum as possible. Thus, the above problem may be posed as an optimization problem, which will be solved using a Genetic Algorithm (GA). The best set of multi-dimensional clusters will be mapped into 2-D for visualization using a Self-Organizing Map (SOM).
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Ali, ABM Shawkat. "K-means Clustering Adopting rbf-Kernel." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch006.

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Clustering technique in data mining has received a significant amount of attention from machine learning community in the last few years as one of the fundamental research area. Among the vast range of clustering algorithm, K-means is one of the most popular clustering algorithm. In this research we extend K-means algorithm by adding well known radial basis function (rbf) kernel and find better performance than classical K-means algorithm. It is a critical issue for rbf kernel, how can we select a unique parameter for optimum clustering task. This present chapter will provide a statistical based solution on this issue. The best parameter selection is considered on the basis of prior information of the data by Maximum Likelihood (ML) method and Nelder-Mead (N-M) simplex method. A rule based meta-learning approach is then proposed for automatic rbf kernel parameter selection.We consider 112 supervised data set and measure the statistical data characteristics using basic statistics, central tendency measure and entropy based approach. We split this data characteristics using well known decision tree approach to generate the rules. Finally we use the generated rules to select the unique parameter value for rbf kernel and then adopt in K-means algorithm. The experiment has been demonstrated with 112 problems and 10 fold cross validation methods. Finally the proposed algorithm can solve any clustering task very quickly with optimum performance.
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Kumar, Pradeep, P. Radha Krishna, Raju S. Bapi, and T. M. Padmaja. "Advances in Classification of Sequence Data." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch007.

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In recent years, advanced information systems have enabled collection of increasingly large amounts of data that are sequential in nature. To analyze huge amounts of sequential data, the interdisciplinary field of Knowledge Discovery in Databases (KDD) is very useful. The most important step within the process of KDD is data mining, which is concerned with the extraction of the valid patterns. Recent research focus in data mining includes stream data mining, sequence data mining, web mining, text mining, visual mining, multimedia mining and multi-relational data mining. Sequence data may be discrete or continuous in nature. Most of the research on discrete sequence data concentrated on the discovery of frequently occurring patterns. However, comparatively less amount of work has been carried out in the area of discrete sequence data classification. In this chapter, data taxonomy is introduced with a review of the state of art for sequence data classification. The usefulness of embedding partial subsequence information extracted using sliding window technique into traditional classifier like kNN has been demonstrated. kNN has been tested with various vector based distance/similarity metrics. Further, with the use of S3M similarity metric, the full subsequence information embedded in the data sequences is extracted. The experimental data taken is DARPA’98 IDS benchmark dataset collected from UCIML dataset repository. The chapter closes by pointing out various application areas of sequence data and also the open issues in sequence data classification problem.
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Cao, Longbing, and Chengqi Zhang. "Domain Driven Data Mining." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch008.

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Quantitative intelligence based traditional data mining is facing grand challenges from real-world enterprise and cross-organization applications. For instance, the usual demonstration of specific algorithms cannot support business users to take actions to their advantage and needs. We think this is due to Quantitative Intelligence focused data-driven philosophy. It either views data mining as an autonomous data-driven, trial-and-error process, or only analyzes business issues in an isolated, case-by-case manner. Based on experience and lessons learnt from real-world data mining and complex systems, this article proposes a practical data mining methodology referred to as Domain-Driven Data Mining. On top of quantitative intelligence and hidden knowledge in data, domain-driven data mining aims to meta-synthesize quantitative intelligence and qualitative intelligence in mining complex applications in which human is in the loop. It targets actionable knowledge discovery in constrained environment for satisfying user preference. Domain-driven methodology consists of key components including understanding constrained environment, business-technical questionnaire, representing and involving domain knowledge, human-mining cooperation and interaction, constructing next-generation mining infrastructure, in-depth pattern mining and postprocessing, business interestingness and actionability enhancement, and loop-closed human-cooperated iterative refinement. Domain-driven data mining complements the data-driven methodology, the metasynthesis of qualitative intelligence and quantitative intelligence has potential to discover knowledge from complex systems, and enhance knowledge actionability for practical use by industry and business.
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Yang, Can, Jun Meng, Shanan Zhu, and Mingwei Dai. "Model Free Data Mining." In Data Mining and Knowledge Discovery Technologies. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-960-1.ch009.

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Input selection is a crucial step for nonlinear regression modeling problem, which contributes to build an interpretable model with less computation. Most of the available methods are model-based, and few of them are model-free. Model-based methods often make use of prediction error or sensitivity analysis for input selection and Model-free methods exploit consistency. In this paper, we show the underlying relationship between sensitivity analysis and consistency analysis for input selection, and then derive an efficient model-free method from our common sense, and then formulate this common sense by fuzzy logic, thus it can be called Fuzzy Consistency Analysis (FCA). In contrast to available methods, FCA has the following desirable properties: 1) it is a model-free method so that it will not be biased on a specific model, exploiting “what the data say” rather than “what the model say”, which is the essential point of data mining – input selection should not be biased on a specific model. 2) it is implemented as efficiently as classical model-free methods, but more flexible than them. 3) it can be directly applied to a data set with mix continuous and discrete inputs without doing rotation. Four benchmark problems study indicates that the proposed method works effectively for nonlinear problems. With the input selection procedure, the underlying reasons which effect the prediction are work out, which helps to gain an insight into a specific problem and servers the purpose of data mining very well.
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Conference papers on the topic "1-960"

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Roth, E. G., M. L. Payne, and M. J. Leary. "Deep Offshore Drilling Case History of North Padre Island 960-' #1." In SPE/IADC Drilling Conference. Society of Petroleum Engineers, 1987. http://dx.doi.org/10.2118/16085-ms.

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Irwin, Mary E., Roxsan Manshouri, Blake Johnson, Hesham M. Amin, and Joya Chandra. "Abstract 960: Targeting Egr-1 is an effective strategy for overcoming kinase inhibitor resistance in CML." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-960.

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Sargsyan, Sevada Mushegh. "The Methodological Guidebook of the Possible Landscape Painting Tasks from One View 1 = (60 + 60) ∙ 4 ∙ 2 = [960; + ∞]." In International Scientific and Practical Conference. TSNS Interaktiv Plus, 2019. http://dx.doi.org/10.21661/r-508981.

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This methodological guidebook is based on the observations and pedagogical experience of the author. This experience is summed up and as a consequence, the theory of possible landscape painting tasks from one view is presented in axiomatic way. The possibilities of 960 and more tasks’ acting from one view during plein air is proved and at the same time not obligated which will be greatly helpful for lecturers of plein air practice for organizing their work more effectively.
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Anderson, Kevin R., and Trevor Steele. "Analysis of a FAME/MLL Screw Multi-Stage Compressor for High Temperature, High Pressure Vapor Compression Refrigeration Cycle." In ASME 2020 Fluids Engineering Division Summer Meeting collocated with the ASME 2020 Heat Transfer Summer Conference and the ASME 2020 18th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/fedsm2020-20002.

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Abstract This paper presents the analysis and design of a compressor for application to a Fatty Acid Methyl Ester (FAME) Methyl Linoleate (MLL) bio-refrigerant cascade working cycle. This working fluid is being used in the topping cycle of an active electronics payload cooling system design to operate at elevated temperatures and pressures such as those witnessed by a Venus lander. The twin-screw, three-stage compressor operates at escalated temperatures of approximately 520 °C (960 °F). The total compressor power of 143.4 W is shared as 43.5 W, 47.7 W, and 53.3 W over stages 1, 2, and 3, respectively. The screw compressor is baselined with a D = 1 inch diameter rotor and an L/D (stroke/bore) ratio of L/D = 2 per stage. The compression ratio corresponds to a volume ratio of 6.5. The swept volume for a 4+6 rotor configuration is estimated to be 1.13 CFM at 2000 RPM with an asymmetric profile and no leakage. The volumetric efficiency of the compressor is estimated to be on the order of 80% due to the higher molecular weight of the FAME/MLL working fluid. The SCORG turbomachinery software is used to verify the thermodynamics analysis and affords a volumetric displacement of 0.025 L/rev at 2000 RPM and 80% adiabatic efficiency.
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Chen, Shih-Shih, Priyadarshini Ravichandran, Yasmine Kieso, et al. "Abstract 960: Mechanisms underlying primary ibrutinib sensitivity in CLL." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-960.

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Mohan, Sriram, Anandh Balakrishnan, and Mrinal C. Saha. "Cure Kinetics of Neat and Nanophased Polyurethane Foams." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-68063.

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In this work, the isothermal cure behavior of a two part polyurethane foam system has been evaluated at temperatures between 25°C–80°C via a rheokinetic method. An ATD CSS 1000-Advanced Polymer Analyzer (APA) rheometer operating in torsion mode was used for this purpose. In the first phase of our work, neat polyurethane foams were investigated and the effects of cure temperature on the final cure modulus and density were documented. The testing procedure consisted of measuring G* as a function of time. The data obtained was fit to a generalized cure kinetics model to evaluate various parameters such as rate constants, reaction orders and activation energies. The rate constants as a function of temperature exhibited a straight line Arrhenius relationship. In the second phase of the work, 1% by weight of cloisite-15A nanoclay was used to manufacture nanocomposite foams. Isothermal cure tests were performed on the nanocomposite foam sample at 25°C. A preliminary investigation of the effect of nanoclay infusion on the final cure properties revealed no significant change. However the nanoclay foam sample exhibited higher reaction rates than its neat counterpart at the same temperature. The cell structures of these foams were studied using a JEOL 960 Scanning Electron Microscope. The micrographs supported the observations that neat foam samples showed an increased density and modulus at lower temperatures than at higher temperatures. The nanoclay sample also showed a higher density relative to its neat counterpart.
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Iskra, Andrej, and Helena Gabrijelčič Tomc. "Analysis of observing and recognition profile facial images using eye tracking system." In 10th International Symposium on Graphic Engineering and Design. University of Novi Sad, Faculty of technical sciences, Department of graphic engineering and design,, 2020. http://dx.doi.org/10.24867/grid-2020-p54.

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Facial images have been the subject of research for many years, using the eye-tracking system. However, most researchers concentrate on the frontal view of facial images. Much less research has been done on faces shown at different angles or profile views of faces in facial images. However, as we know, in reality we often view faces from different angles and not just from a frontal view. In our research we used a profile presentation of facial images and analyzed memory and recognition depending on the display time and dimensions of the facial images. Two tests were performed, i.e. the observation and the recognition test, and we used the well-known yes/no detection theory. We used four different display times in the observation test (1, 2, 4 and 8 seconds) and two different dimensions of facial images 640 × 480 and 1280 × 960). All facial images were taken from the standardized face database Minear&amp;Park. We measured the recognition success which is mostly presented as a discrimination index A’, incorrect recognition (FA – false alarm) and time-spatial method based on fixation duration and saccade length. In this case, eye tracking provides us with objective results when viewing facial images. In the results it was found that extending the display time of facial images improves recognition performance and that the dependence is logarithmic. At the same time, wrong recognition decreased. Both parameters are independent of the dimensions of the facial images. This fact has been proven by some other researchers also for frontal facial images. It was also discovered that with an increase of the display time of facial images an increase of the fixation duration and saccade lengths occurred. In all results we detected major changes at the display time of four seconds, which we consider as a time, where the subjects looked at the whole face and their gaze returned to the center of the face (in our case eye and mouth).
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Authi, K. S., B. J. Evenden та N. Crawford. "ACTION OF GTPγS [GUANOSINE 5∲-0-(3-THIOPHOSPHATE)] ON SAPONIN-PERMEABILISED PLATELETS: INVOLVEMENT OF 'G' PROTEINS IN PLATELET ACTIVATION". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644514.

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Certain ligand-receptor interactions at cell surfaces lead to the phospholipase-C (PLC) hydrolysis of phosphatidyl inositol (4.5) bisphosphate (PIP2). The products serve as intracellular second messengers, e.g. inositol (1.4.5) trisphosphate (IP3) releases Ca2+ from intracellular stores and diacylglycerol activates protein kinase-C. From studies using GTP and analogues (e.g. GTPγS) there is evidence of a key role for a guanine nucleotide binding protein(s) as a link between receptors and PIP2 hydrolysis. We report the actions of GTPγS on washed human platelets permeabilised with saponin (12-14 μg/ml) to allow penetration of low MWt polar substances. The responses to GTPγS are dose dependent (range 9-60 μM) and at 60 μM the agent induces shape change, aggregation and the secretion of 50% of previously incorporated [14C]-5HT. No effect of GTPγS is seen with intact cells. Shape change occurs 25-30 sec after GTPγS; aggregation and secretion is complete after 3 min. When GTP was used (up to 135 μM) with similarly permeabilised platelets no responses were initiated. Phosphatidylinositol turnover was monitored using 32P-labelling before permeabilisation. The addition of 90 μM GTPγS resulted in a 143 ± 23% (n=4) increase in 32P-phosphatidic acid (PA) with respect to the basal levels of “saponised control” cells. These findings suggest that GTPγS stimulates PLC activity through a ‘G’ protein interaction. The GDP analogue (GDPβS) produced no activation responses in saponised platelets but inhibited responses induced by GTPγS in a dose dependent manner (0-480 μM, max inhibition 480 μM). At 960 μM, GDPβS totally inhibited aggregation and secretion initiated by low doses of thrombin (0.1 U/ml) and collagen (1 μg/ml). Identical inhibition by GDPβS of thrombin and collagen-induced activation of intact platelets was observed indicating membrane penetration of this analogue. Shape change effects were not inhibited by GDPSS. The inhibitory effects of GDPSS towards thrombin and collagen induced secretion could be progressively overcome at higher doses of thrombin (0.2 U/ml - 2 U/ml) and collagen (5 μg/ml - 60 μg/ml) suggesting that at higher concentrations these agonists may exert effects through 'G' protein-independent mechanisms.
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Chyla, Michal, Taisuke Miura, Martin Smrž, et al. "50-mJ, 1-kHz Yb:YAG thin-disk regenerative amplifier with 969-nm pulsed pumping." In SPIE LASE, edited by W. Andrew Clarkson and Ramesh K. Shori. SPIE, 2014. http://dx.doi.org/10.1117/12.2039736.

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Ukita, Naoya. "2+1 flavor QCD simulation on a $96^4$ lattice." In The 33rd International Symposium on Lattice Field Theory. Sissa Medialab, 2016. http://dx.doi.org/10.22323/1.251.0075.

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Reports on the topic "1-960"

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Martin, Chester O., R. S. Jackson, and Roy Proffitt. Recnotes. Volume R-96-1. August 1996,. Defense Technical Information Center, 1996. http://dx.doi.org/10.21236/ada316727.

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Esch, R. A. Final report for tank 241-AP-108, grab samples 8AP-96-1, 8AP-96-2 and 8AP-96-FB. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/362385.

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Peters, John F. SMIAC Bulletin. Volume 96-1. Large Deformations in Soil. Defense Technical Information Center, 1995. http://dx.doi.org/10.21236/ada302667.

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Esch, R. A. Final report for tank 241-AY-101, grab samples 1AY-96-1 through 1AY-96-10 and 1AY-96-FB. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/362363.

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Mattern, P. L. Physical and Chemical Sciences Center - research briefs. Volume 1-96. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/380371.

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Fischer, W. Magnetic Field Error Coefficients for Helical Dipoles (1/16/96). Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/1149800.

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Steen, F. H. ,. Westinghouse Hanford. Waste compatibility and final report for Tank 241-A-101, Grab Samples 1A-96-1, 1A-96-2, and 1A-96-3. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/326829.

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Madson, C., and R. Glenn. The Use of HMAC-SHA-1-96 within ESP and AH. RFC Editor, 1998. http://dx.doi.org/10.17487/rfc2404.

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Esch, R. A. 222-S Laboratory analytical report for tank 241-C-106, grab samples 6C-96-1 through 6C-96-16 {ampersand} 6C-96-17-FB. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/16739.

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Esch, R. A. ,. Westinghouse Hanford. Tank 241-AP-106, grab samples, 6AP-96-1 through 6AP-96-3 analytical results for the final report. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/330717.

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