Academic literature on the topic '11C-AZD2184'

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Journal articles on the topic "11C-AZD2184"

1

Shimada, Hitoshi, Hitoshi Shinotoh, Shigeki Hirano, et al. "P2-219: In vivo detection of amyloid deposition using [11C]AZD2184 PET." Alzheimer's & Dementia 8, no. 4S_Part_9 (2012): P335. http://dx.doi.org/10.1016/j.jalz.2012.05.926.

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2

Nyberg, Svante, Maria Eriksdotter Jönhagen, Zsolt Cselényi, et al. "Detection of amyloid in Alzheimer’s disease with positron emission tomography using [11C]AZD2184." European Journal of Nuclear Medicine and Molecular Imaging 36, no. 11 (2009): 1859–63. http://dx.doi.org/10.1007/s00259-009-1182-1.

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3

Shimada, Hitoshi, Hitoshi Shinotoh, Shigeki Hirano, et al. "IC-P-025: In vivo detection of amyloid deposition using [11C]AZD2184 PET." Alzheimer's & Dementia 8, no. 4S_Part_1 (2012): P20. http://dx.doi.org/10.1016/j.jalz.2012.05.057.

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4

Forsberg, Anton, Anders Juréus, Zsolt Cselényi та ін. "Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer’s disease patients". European Journal of Nuclear Medicine and Molecular Imaging 40, № 4 (2013): 580–93. http://dx.doi.org/10.1007/s00259-012-2322-6.

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5

Ito, H., H. Shimada, H. Shinotoh, et al. "Quantitative Analysis of Amyloid Deposition in Alzheimer Disease Using PET and the Radiotracer 11C-AZD2184." Journal of Nuclear Medicine 55, no. 6 (2014): 932–38. http://dx.doi.org/10.2967/jnumed.113.133793.

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6

Rodriguez-Vieitez, Elena, Ruiqing Ni, Balázs Gulyás, et al. "Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study." Eur J Nucl Med Mol Imaging. 42, no. 7 (2015): 1119–32. https://doi.org/10.1007/s00259-015-3047-0.

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PURPOSE: Pathological studies suggest that neuroinflammation is exacerbated by increased beta-amyloid (Aβ) levels in the brain early in Alzheimer's disease (AD). The time course and relationships between astrocytosis and Aβ deposition were examined using multitracer in vivo positron emission tomography (PET) imaging in an AD transgenic mouse model, followed by postmortem autoradiography and immunohistochemistry analysis. METHODS: PET imaging with the amyloid plaque tracer (11)C-AZD2184 and the astroglial tracer (11)C-deuterium-L-deprenyl ((11)C-DED) was carried out in APPswe mice
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7

Mattsson, Patrik, Anton Forsberg, Jonas Persson та ін. "β-Amyloid binding in elderly subjects with declining or stable episodic memory function measured with PET and [11C]AZD2184". European Journal of Nuclear Medicine and Molecular Imaging 42, № 10 (2015): 1507–11. http://dx.doi.org/10.1007/s00259-015-3103-9.

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8

Andersson, Jan D., Katarina Varnäs, Zsolt Cselényi та ін. "Radiosynthesis of the candidate β-amyloid radioligand [11C]AZD2184: Positron emission tomography examination and metabolite analysis in cynomolgus monkeys". Synapse 64, № 10 (2010): 733–41. http://dx.doi.org/10.1002/syn.20782.

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9

Mattsson, Patrik, Zsolt Cselényi, Anton Forsberg Morén та ін. "High Contrast PET Imaging of Subcortical and Allocortical Amyloid-β in Early Alzheimer’s Disease Using [11C]AZD2184". Journal of Alzheimer's Disease, 29 березня 2024, 1–11. http://dx.doi.org/10.3233/jad-231013.

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Abstract:
Background: Deposits of amyloid-β (Aβ) appear early in Alzheimer’s disease (AD). Objective: The aim of the present study was to compare the presence of cortical and subcortical Aβ in early AD using positron emission tomography (PET). Methods: Eight cognitively unimpaired (CU) subjects, 8 with mild cognitive impairment (MCI) and 8 with mild AD were examined with PET and [11C]AZD2184. A data driven cut-point for Aβ positivity was defined by Gaussian mixture model of isocortex binding potential (BPND) values. Results: Sixteen subjects (3 CU, 5 MCI and 8 AD) were Aβ-positive. BPND was lower in sub
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