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1

Cabore, Joseph Waogodo, Humphrey Cyprian Karamagi, Hillary Kipruto, et al. "The potential effects of widespread community transmission of SARS-CoV-2 infection in the World Health Organization African Region: a predictive model." BMJ Global Health 5, no. 5 (2020): e002647. http://dx.doi.org/10.1136/bmjgh-2020-002647.

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The spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been unprecedented in its speed and effects. Interruption of its transmission to prevent widespread community transmission is critical because its effects go beyond the number of COVID-19 cases and deaths and affect the health system capacity to provide other essential services. Highlighting the implications of such a situation, the predictions presented here are derived using a Markov chain model, with the transition states and country specific probabilities derived based on currently available knowledge. A risk of
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2

Anan’in, V. M., B. A. Kalin, V. V. Novikov, and A. V. Sumarokova. "Identification of relaxation maxima of internal friction in the Zr – Nb alloy after nitriding, oxidation in air, and in situ carburization." Physics and Chemistry of Materials Treatment, no. 6 (2021): 26–34. http://dx.doi.org/10.30791/0015-3214-2021-6-26-34.

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The internal friction method was used to study the behavior of the Zr – 1 wt. % Nb alloy after oxidation in air, nitriding in an atmosphere of technical nitrogen, and in situ carburization during measurements. In this case, carbon was deposited on the samples during measurements due to thermal decomposition of vapors of diffusion oil. The pressure in the system was about 10–2 Pa. The temperature dependence of the logarithmic decrement of damped bending vibrations with a frequency of 2.2 – 2.4 Hz was measured on specimens in the form of a rectangular plate 22 × 8 × 0.3 mm in size. The measureme
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3

Krasnovidova, Anatasiya E., Olga I. Simonova, Vera P. Chernevich, Aleksandr V. Pakhomov, Aleksandra P. Reykh, and Aleksandr A. Pushkov. "Genotype-phenotype correlation in siblings with cystic fibrosis." Russian Pediatric Journal 26, no. 3 (2023): 159–67. http://dx.doi.org/10.46563/1560-9561-2023-26-3-159-167.

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Introduction. Despite the genetic counseling, families with cystic fibrosis (CF) patients and modern possibilities of prenatal molecular genetic screening, the occurrence of CF in more than one child in a family is not rare. The same genotype is expected to determine the specific phenotype in CF patients, especially in siblings. However, broad clinical heterogeneity could indicate the influence of secondary genetic factors on the course of the disease.
 The aim of the study is to examine the genotype-phenotype correlation and disease course features in CF siblings, including twins.
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4

Kepert, Cameron J., Lu Wei-Min, Peter C. Junk, Brian W. Skelton, and Allan H. White. "Structural Systematics of Rare Earth Complexes. X (‘Maximally’) Hydrated Rare Earth Acetates." Australian Journal of Chemistry 52, no. 6 (1999): 437. http://dx.doi.org/10.1071/ch98041.

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Extension/augmentation of preexisting work carried out in respect of room-temperature single-crystal X-ray structural characterization of trivalent rare earth acetates, crystallized as ‘maximal’ hydrates, Ln(ac)3.x H2O, from aqueous solution under local ambience, suggests the following array to be prevalent: For Ln = La(-)Pr: triclinic P 1 sesquihydrate, i.e. x = 1½, a ≈ 13·4, b ≈ 10·1, c ≈ 8·6 Å, α ≈ 75·6, β ≈ 103·8, γ ≈ 92·8°, Z = 4 mononuclear f.u., conventional R on |F| for Ln = La, Ce, here, being 0·043, 0·058 for No 3199, 4442 independent ‘observed’ (I > 3σ(I)) diffractometer reflecti
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5

Kousar, Mubeen, Umme Salma, Taous Khan, and Abdul Jabbar Shah. "Antihypertensive Potential of Tartaric Acid and Exploration of Underlying Mechanistic Pathways." Dose-Response 20, no. 4 (2022): 155932582211357. http://dx.doi.org/10.1177/15593258221135728.

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Tartaric acid is capable of balancing blood pressure. It is the main constituent of antihypertensive agents (grapes and wine) and has not been scientifically explored as an antihypertensive remedy. This study aimed to investigate the antihypertensive effect of a low-dose tartaric acid in vivo and explore underlying mechanisms in vitro. Intravenous administration of tartaric acid at the dose of 50 µg/kg caused a % fall in mean arterial pressure (MAP) in normotensive and hypertensive rats [51.5 ± 1.7 and 63.5 ± 2.9% mmHg]. This hypotensive effect was partially inhibited by atropine (1 mg/kg) and
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6

Morgan, George, Sarah Brighton, Mike Laffan, Jenny Goudemand, Bethany Franks, and Alan Finnegan. "The Cost of Von Willebrand Disease in Europe: The CVESS Study." Clinical and Applied Thrombosis/Hemostasis 28 (January 2022): 107602962211205. http://dx.doi.org/10.1177/10760296221120583.

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Background Von Willebrand disease (VWD) is one of the most common inherited bleeding disorders, imposing a substantial health impact and financial burden. The Cost of von Willebrand disease in Europe: A Socioeconomic Study (CVESS) characterises the socio-economic cost of VWD across Germany, Spain, Italy, France, and the UK. Methods A retrospective, cross-sectional design captured 12 months of patient disease management, collected from August-December 2018, for 974 patients. This enabled estimation of direct medical, direct non-medical and indirect costs, utilising prevalence estimates to extra
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7

Castanon, Lourdes, Kamil Hanna, Samer Asmar, et al. "668 Early Enteral Nutrition in Geriatric Burn Patients: Is There a Benefit?" Journal of Burn Care & Research 41, Supplement_1 (2020): S179. http://dx.doi.org/10.1093/jbcr/iraa024.284.

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Abstract Introduction Nutrition is a critical component of acute burn care and wound healing. There is no consensus over the appropriate timing of initiating enteral nutrition (EN) in geriatric burn patients. The aim of our study was to assess the impact of early EN on outcomes in geriatric burn patients. We hypothesized that early EN is associated with improved outcomes. Methods We performed a 2-year (2015–2016) analysis of the ACS-TQIP and included all older adult (age ≥65years) burn patients who received EN. Patients were stratified into two groups based on timing of initiation of EN: Early
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8

Oran, Betul, Jeffrey L. Jorgensen, Sa A. Wang, et al. "Minimal Residual Disease Detected By Multiparameter Flow Cytometry and Complex Karyotype Are the Major Prognostic Factors for Relapse after HCT." Blood 126, no. 23 (2015): 4342. http://dx.doi.org/10.1182/blood.v126.23.4342.4342.

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Abstract Allogeneic hematopoietic cell transplantation (HCT) is considered definitive consolidation therapy for many patients with acute myeloid leukemia (AML) once complete remission (CR) is achieved. Nevertheless, relapse remains a major cause of treatment failure post-HCT.Increasing evidence suggests that the presence of minimal residual disease (MRD) at the time of HCT identifies a subset of patients that is at high risk of relapse. In the present analyses, we sought to determine the impact of MRD detected by 8-color flow cytometry (FC) at HCT on 1-year relapse incidence (RI) in patients t
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9

Vissers, Karin M., Edith J. M. Feskens, Johannes B. van Goudoever, et al. "Timing of Complementary Feeding in Preterm Infants and Prevalence of Overweight and Obesity." JAMA Network Open 8, no. 4 (2025): e252968. https://doi.org/10.1001/jamanetworkopen.2025.2968.

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ImportanceThe appropriate time for initiating complementary feeding in preterm infants is crucial for optimizing growth and preventing long-term health issues, such as overweight. Currently, there are no established guidelines for preterm infants.ObjectiveTo investigate the effect of initiating complementary feeding at corrected age 12 weeks vs 17 weeks on the prevalence of overweight and obesity at corrected age 2 years in preterm infants.Design, Setting, and ParticipantsThis multicenter randomized clinical trial was conducted between May 13, 2016, and April 26, 2021, with follow-up completed
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10

Karampinos, Dimitrios C., Christian Holwein, Stefan Buchmann, et al. "Proton Density Fat-Fraction of Rotator Cuff Muscles Is Associated With Isometric Strength 10 Years After Rotator Cuff Repair: A Quantitative Magnetic Resonance Imaging Study of the Shoulder." American Journal of Sports Medicine 45, no. 9 (2017): 1990–99. http://dx.doi.org/10.1177/0363546517703086.

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Background: Quantitative muscle fat-fraction magnetic resonance (MR) imaging techniques correlate with semiquantitative Goutallier scores with failure after rotator cuff (RC) repair. Purpose: To investigate the relationship of proton density fat fraction (PDFF) of the RC muscles with semiquantitative MR scores, cartilage T2 relaxation times, and clinical isometric strength measurements in patients 10 years after unilateral RC repair. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Bilateral shoulder MR imaging was performed in 13 patients (11 male, 2 female; age, 72 ± 8 yea
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11

White, Paul F., and David S. Warner. "Propofol." Anesthesiology 109, no. 6 (2008): 1132–36. http://dx.doi.org/10.1097/aln.0b013e31818ddba8.

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Pharmacokinetics and pharmacodynamics of propofol infusions during general anesthesia. By Audrey Shafer, Van A. Doze, Steven L. Shafer, and Paul F. White. Anesthesiology 1988; 69:348-56. Reprinted with permission.The pharmacokinetic and pharmacodynamic properties of propofol (Diprivan) were studied in 50 elective surgical patients. Propofol was administered as a bolus dose, 2 mg/kg iv, followed by a variable-rate infusion, 0-20 mg/min, and intermittent supplemental boluses, 10-20 mg iv, as part of a general anesthetic technique that included nitrous oxide, meperidine, and muscle relaxants. For
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12

McRae, Hannah L., Markus Horchler, Nadine Schwarz, et al. "Higher D-Dimer and Prothrombin Fragment 1+2 in Patients Taking Direct Oral Anticoagulants As Compared to Vitamin K Antagonists." Blood 144, Supplement 1 (2024): 1251. https://doi.org/10.1182/blood-2024-210238.

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Introduction: A central question regarding anticoagulant treatment of venous thromboembolism (VTE) is how long maintenance therapy should be continued. Current decision algorithms, which were developed during the era of vitamin K antagonists (VKA), are based on D-dimer measurements before and/or after discontinuation of anticoagulants. However, recent clinical data from the Apidulcis study questioned the validity of this approach in patients taking direct oral anticoagulants (DOACs). One reason for this may be generally higher D-dimer levels in patients on DOACs than in those on VKAs, for whic
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13

Postmus, P. E., E. F. Smit, H. Haaxma-Reiche, et al. "Teniposide for brain metastases of small-cell lung cancer: a phase II study. European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group." Journal of Clinical Oncology 13, no. 3 (1995): 660–65. http://dx.doi.org/10.1200/jco.1995.13.3.660.

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PURPOSE Here we report the results of a phase II study of teniposide, one of the most active drugs against small-cell lung cancer (SCLC), in patients with brain metastases. PATIENTS AND METHODS Patients with SCLC who presented with brain metastases at diagnosis (n = 11) or during follow-up evaluation after treatment (n = 69) were treated with teniposide at a dose of 150 mg/m2 intravenously on days 1, 3, and 5 at 3-week intervals in an outpatient setting. Response in the brain was evaluated by brain computed tomography (CT) after two, six, and 12 courses. RESULTS In 26 of 80 assessable patients
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14

Richardson, Paul G., Angela R. Smith, Brandon M. Triplett, et al. "Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Acute Leukemias: A Subgroup Analysis from the Defibrotide Expanded-Access Program." Blood 128, no. 22 (2016): 3412. http://dx.doi.org/10.1182/blood.v128.22.3412.3412.

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Abstract Introduction Hepatic veno-occlusive disease, also called sinusoidal obstruction syndrome (VOD/SOS), is an unpredictable, potentially life-threatening complication of conditioning for hematopoietic stem cell transplant (HSCT). Reported mean incidence of VOD/SOS following HSCT is an estimated 13.7% (range 0%-62.3%). VOD/SOS with multi-organ dysfunction (MOD) may be associated with >80% mortality. Endothelial cell (EC) damage, triggered by cytotoxic chemotherapeutic conditioning regimens and a prothrombotic-hypofibrinolytic state, is a critical factor in the pathophysiology of VOD/SOS
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15

Castillo, Jorge J., Joshua Gustine, Andrew Keezer, et al. "Ibrutinib Dose Reduction Does Not Affect Progression-Free Survival in Patients with Waldenstrom Macroglobulinemia." Blood 132, Supplement 1 (2018): 1598. http://dx.doi.org/10.1182/blood-2018-99-111626.

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Abstract Introduction: Ibrutinib is an oral Bruton Tyrosine Kinase inhibitor, approved for the treatment of symptomatic Waldenstrom Macroglobulinemia (WM). MYD88 and CXCR4 mutations affect progression-free survival (PFS) in patients with WM. In some cases, ibrutinib dose reductions are needed for the management of toxicity. However, it remains unclear if ibrutinib dose reductions adversely affect PFS in WM patients. Methods: We evaluated 217 consecutive patients with the clinicopathological diagnosis of WM who were symptomatic and received treatment with ibrutinib. We analyzed relevant clinica
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16

Sunguya, Bruno, Erick Alexander Mboya, Mucho Mizinduko, et al. "Epidemiology of syphilis infections among pregnant women in Tanzania: Analysis of the 2020 national representative sentinel surveillance." PLOS ONE 18, no. 8 (2023): e0285069. http://dx.doi.org/10.1371/journal.pone.0285069.

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Background Syphilis has detrimental effects on the health of the mother and that of both fetuses and newborns exposed in utero or at delivery. Understanding its local epidemiology is essential for policies, planning, and implementation of targeted preventive interventions. Using data from the 2020 National Sentinel Surveillance of pregnant women attending antenatal clinics (ANCs) in Tanzania we determined the prevalence and determinants of syphilis among pregnant women in Tanzania mainland. Methodology The ANC surveillance was conducted in 159 ANC sites from all 26 regions of Tanzania’s mainla
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17

Semenova, Lioubov I., and Allan H. White. "Structural Systematics of Rare Earth Complexes. XIX (Hydrated) 1 : 2 Mononuclear Adducts of Lanthanoid(III) Chlorides with 2,2′-Bipyridine and 1,10-Phenanthroline." Australian Journal of Chemistry 52, no. 6 (1999): 571. http://dx.doi.org/10.1071/ch98052.

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Room-temperature single-crystal X-ray structure determinations are recorded for a number of adducts of hydrated lanthanoid(III) trichlorides with 2,2′-bipyridine (‘bpy’) and 1,10-phenanthroline (‘phen’), crystallized from water, methanol or ethanol solutions, containing mononuclear arrays with 1 : 2 Ln/bpy or phen stoichiometry. LaCl3/phen/H2O(1 : 3 : 9), [(phen)2La(OH2)5]Cl3.phen.4H2O, although of overall 1 : 3 LaCl3/phen stoichiometry, has a lattice phen; it is orthorhombic, Pnna, a 19·947(7), b 16·457(5), c 12·213(2) Å, Z = 4; conventional R on |F| was 0·030 for No 2567 ‘observed’ (I >3σ
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18

Andrade, Marcio M., Anel Montes, Ilda Murillo, Jose M. Grasa, Teresa Baringo, and Pilar Giraldo. "RIT with 90Y Ibritumomab Tiuxetan in Patients with Non-Hodgkin Lymphoma Over 65 Years." Blood 120, no. 21 (2012): 2742. http://dx.doi.org/10.1182/blood.v120.21.2742.2742.

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Abstract Abstract 2742 Introduction: 90Y Ibritumomab tiuxetan (90Y-IT) has become an efficient alternative to therapy in non-Hodgkin Lymphoma, mainly in elderly patients. The aim of this study is to analyse our updated information of patients treated with 90YIbritumomab/tiuxetan in a prospective study according clinical practice setting and to analyse treatment outcome. Subjects and Methods: 39 non Hodgkin lymphoma patients were included in a clinical protocol conducted by a multidisciplinary team and treated in the same centre. According the inclusion criteria: patients over 65 years old diag
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Baruselli, P. S., M. O. Marques, L. M. Vieira, J. L. Konrad, and G. A. Crudeli. "Aplicación de biotecnologías para una mayor producción de terneros." Revista Veterinaria 26, no. 2 (2016): 154. http://dx.doi.org/10.30972/vet.262231.

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20

Hewlett, Sarah, Celia Almeida, Nicholas Ambler, et al. "Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT)." Annals of the Rheumatic Diseases 78, no. 4 (2019): 465–72. http://dx.doi.org/10.1136/annrheumdis-2018-214469.

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ObjectivesTo see if a group course delivered by rheumatology teams using cognitive-behavioural approaches, plus usual care, reduced RA fatigue impact more than usual care alone.MethodsMulticentre, 2-year randomised controlled trial in RA adults (fatigue severity>6/10, no recent major medication changes). RAFT (Reducing Arthritis Fatigue: clinical Teams using CB approaches) comprises seven sessions, codelivered by pairs of trained rheumatology occupational therapists/nurses. Usual care was Arthritis Research UK fatigue booklet. Primary 26-week outcome fatigue impact (Bristol RA Fatigue Effec
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21

Nieto, R., R. Quintana, E. Borba, et al. "POS1519 BASELINE CHARACTERISTICS OF A LONGITUDINAL, MULTINATIONAL, MULTIETHNIC STUDY OF LUPUS PATIENTS, WITH OR WITHOUT LUPUS NEPHRITIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1118.1–1120. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2738.

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BackgroundClinically evident kidney disease eventually occurs in up to one-half of SLE patients.ObjectivesTo describe sociodemographic, clinical, serological and treatment characteristics of a multicenter and multiethnic Latin American SLE cohort of patients with or without lupus nephritis (LN)MethodsGLADEL2.0 is an ongoing observational cohort. Patients were categorized according to renal involvement: Group I (LN never); II (prevalent renal involvement currently inactive); III (prevalent renal involvement, currently active) and IV (incident renal involvement). Demographic, clinical manifestat
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22

McSorley, Lynda M., Fathiya Al Rahbi, Mehala Tharmabala, et al. "Real-world analysis of clinical and economic impact of 21-gene recurrence score (RS) testing in early-stage breast cancer (ESBC) in Ireland." Journal of Clinical Oncology 38, no. 15_suppl (2020): 540. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.540.

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540 Background: Treatment of hormone receptor positive (HR+) ESBC is evolving. The use of chemotherapy (CT) is declining with use of the 21-gene RS assay. This validated tool predicts the likelihood of adjuvant CT benefit in HR+ ESBC. Results from the TAILOR-x study suggest up to 70% of HR+ node negative ESBC patients (pts) may avoid CT with RS ≤25. Our objectives were to assess the clinical and economic impact of RS testing on treatment decisions using real-world data. Methods: From October 2011 to February 2019, a retrospective, cross-sectional observational study was conducted of HR+ node n
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23

Rodriguez, Karla Baez, Nicole Torres Rivera, Janevi Rebernigg, et al. "PSUN146 Diabetes, Obesity, and Diabetes-Obesity Overlap Syndrome in Hospitalized Adult COVID-19 Patients: Comorbidity Dose is The Thing!" Journal of the Endocrine Society 6, Supplement_1 (2022): A365. http://dx.doi.org/10.1210/jendso/bvac150.758.

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Abstract Excess risk for mortality in hospitalized adults with COVID-19 has been linked to extant chronic conditions, especially obesity (Obes), diabetes (DM) or combination (ObesDM). We investigated dose-response interactions between Elixhauser Comorbidity Index (ECI) and comorbidity ensembles including Obes, DM, ObesDM or Control. Presentation demographics, putative COVID-19 severity markers, and administrative data including ICD-10 codes to measure ECI (AHRQ, v2022.1, 0-38 categories) were extracted under IRB exemption from electronic medical records. Youden's J statistic identified ECI35 p
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24

Aoki, Naomi J., Kylie Venardos, Nick Andrianopoulos, et al. "Use of Blood Components in Major Obstetric Hemorrhage: Preliminary Findings from the Australian and New Zealand Massive Transfusion Registry (ANZ-MTR)." Blood 124, no. 21 (2014): 1563. http://dx.doi.org/10.1182/blood.v124.21.1563.1563.

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Abstract Introduction: Major obstetric hemorrhage (MOH) can develop rapidly and, due to the unique characteristics of maternity patients, early recognition and management can be challenging. Use of blood components in MOH can be life-saving however there is uncertainty about optimal use of these products and the role of adjunctive therapies. The ANZ-MTR generates observational data on current transfusion management and outcomes in critically bleeding patients receiving massive transfusion (MT) across all clinical settings. This study aimed to describe the transfusion strategies used in the MOH
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Hunault-Berger, Mathilde, Yves Gruel, Jean-Luc Harousseau, et al. "Evolution of Antithrombin (AT) and Fibrinogen (Fg) Levels during Induction Chemotherapy with L-Asparaginase (Asp) in Adult Patients with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL). Clinical Outcomes and Use of Coagulation Supportive Treatments: The CAPELAL Study." Blood 104, no. 11 (2004): 4486. http://dx.doi.org/10.1182/blood.v104.11.4486.4486.

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Abstract The incidence of AT and Fg deficiency and of thrombotic and bleeding events after Asp has been well evaluated in children with ALL, but little is known in adults. In this study, the incidence of these events and the use of coagulation supportive treatments was evaluated in 214 adult patients with ALL (n= 191) or LBL (n=23) included in the GOELAL02 trial (Blood 2004, in press). The induction therapy included steroids (40 mg/m2/d d1-21), vincristine (2 mg d1, 8, 15, 22), idarubicine (5 mg/m2 d1, 8,15, 22) and Asp (7500 UI/m2 d10, 13, 16, 19, 22, 25) delivered through a central venous ac
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26

Klinkby, L., N. Balling, and J. Liboriussen. "Erratum." Bulletin of the Geological Society of Denmark 45 (February 28, 1998): 87. http://dx.doi.org/10.37570/bgsd-1998-45-26.

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In the article by Klinkby et al. ‘A deep seismic reflection line in the Danish Central Graben’ (Bulletin of the Geological Society of Denmark, Vol. 44(2), pp. 151–159, 1998), Tables 1 and 2 were unfortunately omitted. These are printed below.
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Bowmaker, Graham A., Effendy, Robert D. Hart, John D. Kildea, and Allan H. White. "Lewis-Base Adducts of Group 11 Metal(I) Compounds. LXXIII Synthesis, Spectroscopy and Structural Systematics of New 1 : 1 'Cubane' Tetramers of Copper(I) and Silver(I) Halides with Triphenylarsine." Australian Journal of Chemistry 50, no. 6 (1997): 653. http://dx.doi.org/10.1071/c96039.

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Syntheses and room-temperature single-crystal X-ray structural characterization of a number of 1 : 1 ‘cube tetramer’ adducts of copper(I) and silver(I) halides, MX, with triphenylarsine, AsPh3, are recorded, being [XM(AsPh3)]4. The CuBr adduct, obtained unsolvated from toluene, orthorhombic Pbcn, a 17·844(5), b 20·778(8), c 18·430(4) Å, Z = 4 tetramers, conventional R on |F| 0·058 for No 1309 independent ‘observed’ reflctions (I > 3σ(I)), is isomorphous with previously recorded [ClAg(PPh3)]4, the tetramer having crystallographically imposed 2 symmetry. The CuI adduct, previously recorded as
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Fenaux, Pierre, Agnes Guerci-Bresler, Petra Muus, et al. "Efficacy and tolerability of lenalidomide (LEN) in patients (pts) 75 and older versus those younger than 75 with RBC transfusion-dependent low/int-1-risk MDS and del 5q." Journal of Clinical Oncology 30, no. 15_suppl (2012): 6522. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.6522.

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6522 Background: LEN is the approved treatment for pts with RBC transfusion-dependent Low/Int-1-risk MDS and del 5q. In 2 multicenter trials (MDS-003/-004) LEN lead to RBC transfusion independence (TI) for ≥ 26 wks in 35–58% of pts and cytogenetic response (CyR) in 25–73%. Most common grade (G) 3–4 adverse events (AE) were neutropenia and thrombocytopenia, a safety concern in elderly pts. We evaluated efficacy and tolerability of LEN in pts ≥ 75 y vs < 75 y in MDS-003/-004 trials. Methods: Pts received LEN 5 mg × 28 d, 10 mg × 21 d, or 10 mg × 28 d (all 28 d cycles). Dose reductions were re
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Fan, Lan-Feng, En-Cheng Kang, Mariche B. Natividad, et al. "The Role of Benthic TA and DIC Fluxes on Carbon Sequestration in Seagrass Meadows of Dongsha Island." Journal of Marine Science and Engineering 12, no. 11 (2024): 2061. http://dx.doi.org/10.3390/jmse12112061.

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Coastal blue carbon ecosystems sequester carbon, storing it as plant biomass and particulate organic matter in sediments. Recent studies emphasize the importance of incorporating dissolved inorganic and organic forms into carbon assessments. As sediment-stored organic matter decomposes, it releases dissolved inorganic carbon (DIC) and total alkalinity (TA), both of which are critical for regulating the partial pressure of CO2 (pCO2) and thus carbon sequestration. This study investigated the role of benthic DIC and TA fluxes in carbon sequestration within seagrass meadows in Dongsha Island’s in
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30

Falczyk, Felix, and Johanna Herschel. "Material for Economic Experience: Feminist Management." Identities: Journal for Politics, Gender and Culture 13, no. 1-2 (2016): 135–59. http://dx.doi.org/10.51151/identities.v13i1-2.316.

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Author(s): Felix Falczyk and Johanna Herschel
 Title (English): Material for Economic Experience: Feminist Management
 Title (German): Material Für Ökonomische Erfahrung: Feministisches Management
 Translated by (German to English): Felix Falczyk and Johanna Herschel
 Journal Reference: Identities: Journal for Politics, Gender and Culture, Vol. 13, No. 1-2 (Winter 2016 - Summer 2017)
 Publisher: Institute of Social Sciences and Humanities – Skopje 
 Page Range: 135-159
 Page Count: 26
 Citation (English): Felix Falczyk and Johanna Herschel, “Material for
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31

Wathes, C. M., T. G. M. Demmers, N. Teer, et al. "Production responses of weaned pigs after chronic exposure to airborne dust and ammonia." Animal Science 78, no. 1 (2004): 87–97. http://dx.doi.org/10.1017/s135772980005387x.

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AbstractNine hundred and sixty weaned pigs were exposed for 5·5 weeks to controlled concentrations of airborne dust and ammonia in a single, multi-factorial experiment. Production and health responses were measured but only the former are reported here. The treatments were a dust concentration of either 1·2, 2·7, 5·1 or 9·9 mg/m3(inhalable fraction) and an ammonia concentration of either 0·6, 10·0, 18·8 or 37·0 p. p. m., which are representative of commercial conditions. The experiment was carried out over 2·5 years and pigs were used in eight batches, each comprising five lots of 24 pigs. Eac
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Ыбрайкожа, Нуржан, Асет Токтамысов, Эльвира Сагиндыкова, Диана Семирханова та Айгул Серикбаева. "ВЛИЯНИЕ БИОЛОГИЧЕСКИХ ПРЕПАРАТОВ И КОМПЛЕКСНЫХ ЖИДКИХ УДОБРЕНИЙ НА ЭЛЕМЕНТЫ СТРУКТУРЫ УРОЖАЯ РИСА В КАЗАХСТАНСКОМ ПРИАРАЛЬЕ". Izdenister natigeler, № 2 (98) (29 червня 2023): 264–74. http://dx.doi.org/10.37884/2-2023/26.

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Все большую популярность у земледельцев Приаралья приобретает сегодня применение жидкого биологического удобрения, содержащее микроэлементы. Биологическое удобрение имеет нейтральную или слабощелочную реакцию, не загрязнено техногенными радионуклидами, невзрывоопасно. Низкая температура кристаллизации – 2°С и замерзания –26°С – позволяет транспортировать жидкое биологическое удобрение круглый год так же, как и хранить, особенно, в заглубленных в почву утепленных хранилищах из бетона и асфальта с внутренним покрытием из пленки. Сотрудниками института рисоводства были проведены исследования по э
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Eisen, Alon, Marc P. Bonaca, Petr Jarolim, et al. "High-Sensitivity Troponin I in Stable Patients with Atherosclerotic Disease in the TRA 2°P - TIMI 50 Trial." Clinical Chemistry 63, no. 1 (2017): 307–15. http://dx.doi.org/10.1373/clinchem.2016.264788.

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Abstract BACKGROUND Cardiac troponin I, measured with a high-sensitivity assay (hs-TnI), is well-established for risk prediction in acute coronary syndromes. However, its prognostic role in stable atherosclerotic disease, particularly for future myocardial infarction (MI), is less well defined. METHODS We measured hs-TnI (Abbott ARCHITECT) in 15833 patients with prior MI, ischemic stroke, or peripheral arterial disease from the placebo-controlled Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P)–Thrombolysis in Myocardial Infarction (TIMI) 50 tr
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Bobriakov, N. A., S. I. Petrov, E. V. Sereda, et al. "Intraoperative neurophysiological monitoring in patients with delayed cerebral ischemia after clipping of ruptured arterial aneurysms." Russian journal of neurosurgery 26, no. 2 (2024): 26–36. http://dx.doi.org/10.17650/1683-3295-2024-26-2-26-36.

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Aim. Research of significant changes in parameters (SCP) by intraoperative neurophysiological monitoring (IONM) during clipping of ruptured cerebral aneurysms in patients with delayed cerebral ischemia (DCI) in the postoperative period.Materials and methods. The study included 16 patients, 7 (43.8 %) men and 9 (56.2 %) women, aged 51.1 ± 9.3 years, who underwent clipping of ruptured cerebral aneurysms for the period 2016–2021, in which the neurological deficit (ND) remained at the preoperative level on the first postoperative day, but increased by the end of hospitalization. In order to study
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Garifullin, Andrey, Sergei Voloshin, Vasily Shuvaev, et al. "Significance of Modified Risk Stratification Msmart 3.0 and Autologous Stem Cell Transplantation for Patients with Newly Diagnosed Multiple Myeloma." Blood 134, Supplement_1 (2019): 5593. http://dx.doi.org/10.1182/blood-2019-130092.

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Background The risk-stratification systems are repeatedly updated in accordance with the emergence of new information about the prognostic impact of anomalies and other factors. The most extensive and modern system in this time is mSMART risk stratification involving many parameters such as genetic anomalies, albumin, beta-2-microglobulin, LDH, Plasma Cell S-phase and GEP levels. It is possible to use risk-adapted treatment programs with or without ASCT. Nevertheless, the role of complex karyotype, combination of genetic abnormalities and ASCT remains unclear. Aims To estimate the genetic abno
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Zhang, Feng, Hai-Xia Song, Li-Hua Zheng, Yan-Bo An, and Peng Liu. "Long-term clinical efficacy of drug-coated balloon angioplasty for TASCII C/D femoropopliteal lesions in older patients with chronic limb-threatening ischemia: A retrospective study." Medicine 103, no. 33 (2024): e39331. http://dx.doi.org/10.1097/md.0000000000039331.

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This study aimed to evaluate the long-term clinical outcomes of drug-coated drug (DCB) angioplasty for long femoropopliteal lesions in older patients with chronic limb-threatening ischemia (CLTI). In this multi-center retrospective study, we enrolled 119 patients with CLTI due to Trans-Atlantic Inter-Society Consensus (TASCII) C/D femoropopliteal lesions who underwent DCB angioplasty. A total of 119 patients with 122 limbs (TASCII C = 67, 54.9%; TASCII D = 55, 45.1%) were enrolled. At 36-month follow-up, primary patency, assisted primary patency, secondary patency, and freedom from target lesi
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Alpizar-Rodriguez, D., F. Irazoque-Palazuelos, T. S. Rodriguez-Reyne, et al. "POS1242 FACTORS ASSOCIATED WITH MORTALITY IN PATIENTS WITH RHEUMATIC DISEASES AND COVID-19 IN MEXICO." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 904.1–904. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3342.

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Background:As of the 25th of January 2021, more than 150 thousand deaths as consequence of COVID-19 have been reported in Mexico [1]. Advanced age, male gender and comorbidities have been described as risk factors for severe disease and mortality in general population [2]. COVID-19 mortality in Mexican patients with rheumatic and musculoskeletal diseases (RMDs) is unknown.Objectives:To describe characteristics of Mexican patients with RMDs and COVID-19, and to analyse factors associated with mortality.Methods:The Global Rheumatology Alliance COVID-19 (GRA) physician reported registry, is an in
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Sharov, D. A., I. V. Darmov, I. V. Kosenkov, et al. "Possibility of Using Disposable Polymeric Containers in the Production Technology of Live Plague Vaccine." Problems of Particularly Dangerous Infections, no. 4 (January 10, 2024): 149–55. http://dx.doi.org/10.21055/0370-1069-2023-4-149-155.

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The aim of the work was to assess the possibility of using disposable polymeric containers in the production technology of the live plague vaccine.Materials and methods. We deployed the vaccine strain Yersinia pestis ЕV NIIEG for the work. A standard disposable 10 L Flexboy type polymeric container manufactured by Sartorius Stedim Biotech, equipped with Sartopore 2 filter capsules, was used for submerged cultivation of plague microbe inoculum. This method was compared to the regulated technology for obtaining seed cultures using glass bottles with a volume of 20 liters. The control of the prod
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39

Khan, Hina, Harish Saiganesh, Adam J. Olszewski, et al. "Is there a genomic fingerprint of Radon (Rn)-induced lung cancer (LC)? Comparison of genomic alterations in LC specimens from high and low Rn zones." Journal of Clinical Oncology 38, no. 15_suppl (2020): 1572. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.1572.

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1572 Background: Rn-222 is a radioactive gas found in rocks and soil. It emits alpha particles that cause dsDNA breaks and increase potential for carcinogenesis. Rn is the 2nd leading cause of LC in the US after smoking. EPA estimates >15,000 deaths/yr (9% of LC deaths) from Rn. We hypothesize that the impact of Rn exposure may be reflected in LC gene mutation (mut) profiles. Methods: Using commercial NGS assays, we retrospectively analyzed genomic DNA alterations in FFPE specimens from 159 LC patients (pts) from the Lifespan Cancer Institute in Rhode Island (2014- 2019), followed by valida
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Wallstein, Johannes, and Ludwig Krapf. "Rezension von: Krapf, Ludwig u.a. (Hrsg.), Stuttgarter Hoffeste ..." Schwäbische Heimat 31, no. 3 (2025): 218. https://doi.org/10.53458/sh.v31i3.16591.

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Ludwig Krapf und Christian Wagenknecht (Hgg): Stuttgarter Hoffeste. Texte und Materialien zur höfischen Repräsentation im frühen 17. Jahrhundert. (Neudruck deutscher Literaturwerke, N. F., Band 26). Verlag Max Niemeyer Tübingen 1979. LII, 514 Seiten, 8 Tafeln, zahlreiche Faksimiles. Leinen DM 158,- Ludwig Krapf und Christian Wagenknecht (Hgg): Stuttgarter Hoffeste. Esaias van Hülsen und Matthäus Merian: Repraesentatio der fvrstlichen Avfzvg und Ritterspil. (Neudrucke deutscher Literaturwerke, N. F., Band 27.) Verlag Max Niemeyer Tübingen 1979. X, 159 Seiten, 83 Abb., davon 2 auf Falttafeln. Le
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41

Small, Julie A. "Serum mineral concentrations in relation to parturition in beef heifers and cows fed conserved forage." Canadian Journal of Animal Science 77, no. 1 (1997): 63–68. http://dx.doi.org/10.4141/a96-043.

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A study was undertaken to examine the relationship between serum mineral concentrations and calving ease in beef cattle fed conserved forage. Jugular blood samples were taken from multiparous cows (n = 6) and 2-yr-old primparous heifers (n = 9) that calved without assistance and 2-yr-old primparous heifers that required assistance with calving (n = 6) on days −7, 0 and +7 after parturition. Sera were analyzed for Ca, P, Mg, K, S, Na, Cu, Zn and B by ICAP and for progesterone by RIA. From 2 mo before and throughout the calving season cattle were given ad libitum round bale grass-legume silage (
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42

Munawaroh, Beti, and Muhsinatun Siasah Masruri. "THE EFFECTIVENESS OF PROBLEM BASED LEARNING AND DISCOVERY LEARNING MODEL TOWARD LEARNING OUTCOME IN GEOGRAPHY ON STUDENTS WITH EXTERNAL LOCUS OF CONTROL." Geosfera Indonesia 4, no. 1 (2019): 56. http://dx.doi.org/10.19184/geosi.v4i1.9240.

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Based on the development in education, Indonesia has implemented a new curriculum called K13, in this curriculum, implementing the scientific approach is mandatory. Unsuitable learning model results in minimum students’ learning outcome in geography. In addition, locus of control also affects the students' learning outcome since students with internal LoC are alway better than students with external LoC. To cope with this issue, a suitable learning model is necessary: PBL and DL model. A suitable model is expected to be able to improve students' learning outcome — the present study aimed to ex
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Kaye, S. B., J. Paul, J. Cassidy, et al. "Mature results of a randomized trial of two doses of cisplatin for the treatment of ovarian cancer. Scottish Gynecology Cancer Trials Group." Journal of Clinical Oncology 14, no. 7 (1996): 2113–19. http://dx.doi.org/10.1200/jco.1996.14.7.2113.

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PURPOSE In 1992, we reported the first results of a randomized study in ovarian cancer, comprising two doses of cisplatin and indicated a significant difference (P = .0008) in median survival. Four years later, we now describe the results of this trial. PATIENTS AND METHODS After a median follow-up of 4 years and 9 months, 115 of 159 cases of advanced ovarian cancer, originally randomized to receive six cycles of cyclophosphamide 750 mg/m2 and either a high dose (HD) of 100 mg/m2 cisplatin or a low dose (LD) of 50 mg/m2 (LD) cisplatin, have now died. RESULTS The overall survival for HD and LD
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Hasan, Rida, Kirtikumar Upadhyay, Nathan Breit, et al. "Changes in platelet transfusion thresholds utilized in the NICU since PlaNeT-2." American Journal of Clinical Pathology 162, Supplement_1 (2024): S172—S173. http://dx.doi.org/10.1093/ajcp/aqae129.379.

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Abstract Background Use of prophylactic platelet transfusions in the neonatal setting is a common practice due to concerns about bleeding despite evidence of a developmental mismatch with transfusion of adult platelets. The Platelets for Neonatal Transfusion-Study 2 (PlaNeT-2) published in January 2019 showed that using higher platelet thresholds (50 x 109/L) was associated with more adverse outcomes and no improvement in bleeding events compared to lower platelet thresholds (25 x 109/L). Following this trial, implementation of a lower threshold was provider dependent as there were no changes
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45

Shalahuddin, Iwan, Mamat Lukman, and Udin Rosidin. "Pembentukan dan Pemberdayaan Program Proslah (Peer Group Stunting Sekolah) dalam Upaya Pencegahan Stunting di SDN 1-2 Sukamenteri Garut." Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) 6, no. 6 (2023): 2195–204. http://dx.doi.org/10.33024/jkpm.v6i6.9347.

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ABSTRAK Belakangan stunting sedang hangat diperbincangkan banyak orang, khususnya para ibu. Berdasarkan WHO, stunting adalah gangguan tumbuh kembang anak yang disebabkan kekurangan asupan gizi, terserang infeksi, maupun stimulasi yang tak memadai. Jumlah penderita stunting di Indonesia terus menurun. Tetapi langkah pencegahan stunting sangat perlu dilakukan, selengkapnya berikut ini: Memenuhi kebutuhan gizi sejak hamil. Tindakan yang relatif ampuh dilakukan untuk mencegah stunting pada anak adalah selalu memenuhi gizi sejak masa kehamilan. Berdasarkan Karakteristik Antropometri di SDN 1 dan 2
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46

Rodríguez-Cortés, Francisco J., Hornero Jorge Jimenez, Díaz Juan F. Alcalá, et al. "Daylight Saving Time transitions and Cardiovascular Disease in Andalusia: Time Series Modeling and Analysis Using Visibility Graphs." Angiology 74, no. 9 (2022): 868–75. https://doi.org/10.1177/00033197221124779.

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The present study aimed to determine whether transitions both to and from daylight saving time (DST) led to an increase in the incidence of hospital admissions for major acute cardiovascular events (MACE). To support the analysis, natural visibility graphs (NVGs) were used with data from Andalusian public hospitals between 2009 and 2019. We calculated the incidence rates of hospital admissions for MACE, and specifically acute myocardial infarction and ischemic stroke during the 2 weeks leading up to, and 2 weeks after, the DST transition. NVG were applied to identify dynamic patterns. The stud
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Baron, Frederic, Ruggeri Annalisa, Eric Beohou, et al. "Reduced-Intensity Versus Myeloablative Conditioning for Unrelated Cord Blood Transplantation in Adults with Acute Leukemia: A Report from Eurocord, the Acute Leukemia Working Party and the Cord Blood Committee of the Cellular Therapy & Immunobiology Working Party of the European Group for Blood and Marrow Transplantation." Blood 126, no. 23 (2015): 155. http://dx.doi.org/10.1182/blood.v126.23.155.155.

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Abstract BACKRGOUND. Non-relapse mortality (NRM) is the first cause of treatment failure after unrelated cord blood transplantation (UCBT) following myeloablative conditioning (MAC). In the last decade, reduced-intensity conditionings (RIC) for UCBT have been developed with the aim of reducing NRM and allowing older patients and those with medical comorbidities to benefit from UCBT. The aim of our retrospective registry study was to compare outcomes of acute leukemia (AL) adult patients given UCBT after either RIC or MAC regimens. Regimens were classified as MAC or RIC based on EBMT criteria.
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48

Nückel, Holger, Ulrich H. Frey, Maja Bau, et al. "Association of a novel regulatory polymorphism (−938C>A) in the BCL2 gene promoter with disease progression and survival in chronic lymphocytic leukemia." Blood 109, no. 1 (2006): 290–97. http://dx.doi.org/10.1182/blood-2006-03-007567.

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Abstract Bcl-2 plays a key role in the regulation of apoptosis. We investigated the role of a novel regulatory single-nucleotide polymorphism (−938C>A) in the inhibitory P2 BCL2 promoter in B-cell chronic lymphocytic leukemia (B-CLL). The −938C allele displayed significantly increased BCL2 promoter activity and binding of nuclear proteins compared with the A allele. Concomitantly, Bcl-2 protein expression in B cells from CLL patients carrying the −938 AA genotype was significantly increased compared with CC genotypes. Genotype distribution between 123 CLL patients (42 AA, 55 AC, 26 CC) and
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49

N., Agnihotri, Dass R., and R. Mehta J. "Spectrophotometric determination of vanadium(v) as its 6-chloro-3-hydroxy-2-[2' -( 5' -methylfuryl)]-4H -chromen-4-one complex." Journal of Indian Chemical Society Vol. 77, May 2000 (2000): 264–66. https://doi.org/10.5281/zenodo.5868468.

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Department of Chemistry, Kurukshetra University, Kurukshetra-136 119, Haryana, India <em>Manuscript received 26 April 1999. revised 27 September 1999. accepted 12 February 2000</em> A simple and sensitive spectrophotometric method for the determination of vanadium(v) has been developed using 6-chloro-3-bydroxy-2-[2&#39;-(5&#39;-metbylfuryl)]-4<em>H</em>-chromen-4-one as a complexing ligand. The dark yellow (1 : 1) coloured species extracted into chloroform from 0.3 <em>M</em> CH<sub>3</sub>COOH medium shows &lambda;<sub>max</sub> at 432 nm. The method is free from the interference of a large n
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Fahey, Margaret C., Marion E. Hare, Gerald W. Talcott, et al. "Characteristics Associated With Participation in a Behavioral Weight Loss Randomized Control Trial in the U.S. Military." Military Medicine 184, no. 3-4 (2018): e120-e126. http://dx.doi.org/10.1093/milmed/usy199.

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Abstract Introduction Effective recruitment and subsequent enrollment of diverse populations is often a challenge in randomized controlled trials, especially those focused on weight loss. In the civilian literature, individuals identified as racial and ethnic minorities, men, and younger and older adults are poorly represented in weight loss interventions. There are limited weight loss trials within military populations, and to our knowledge, none reported participant characteristics associated with enrollment. There may be unique motives and barriers for active duty personnel for enrollment i
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