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Journal articles on the topic '159.9.016 (043.2)'

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Published: 30 May 2022
Last updated: 31 July 2025

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1

Martins, P. A., and A. L. Sawaya. "Evidence for impaired insulin production and higher sensitivity in stunted children living in slums." British Journal of Nutrition 95, no. 5 (2006): 996–1001. http://dx.doi.org/10.1079/bjn20061754.

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The objective of the present study was to investigate the changes in glucose and insulin metabolism in nutritionally stunted children that can be involved in the appearance of chronic diseases in adulthood. For this purpose, sixty-one children were selected, thirty-five boys and twenty-six girls, residents of slums in S˜o Paulo, Brazil. The children were classified according to the height-for-age as stunted (1·5 Z-score; n 21) or non-stunted (≥1·5 Z-score; n 40). The glucose and insulin plasma levels were determined and, from these values, the indexes that evaluate the pancreatic ·-cell functi
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2

Bussel, James B., Allison M. Schindler, and Elliott B. Grossbard. "R935788: A Phase II, Single Center, Open Label, Efficacy and Safety, Ascending Dose, Pilot Study for the Treatment of Adult Immune Thrombocytopenic Purpura (ITP)." Blood 110, no. 11 (2007): 1310. http://dx.doi.org/10.1182/blood.v110.11.1310.1310.

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Abstract Syk kinase is central to FcR and B-cell signaling in inflammatory cells. By inhibiting syk, and thereby IgG signaling, R788 (a small molecule prodrug for biologically active R406), inhibits the downstream activation of mast cells, macrophages and B-cells. (Braselmann S. Pharm Exp Ther. 2006). Preclinical study showed that R788 minimized thrombocytopenia in mice treated with anti-platelet antibodies (Crow, A.R. Blood 2005). In this study, adult, refractory ITP patients (pts) were treated with escalating doses of R788 in cohorts of ≥3 pts to evaluate safety and efficacy. After a cohort
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3

Costanzo, Andrew, Dongli Liu, Caryl Nowson, et al. "A low-fat diet up-regulates expression of fatty acid taste receptor gene FFAR4 in fungiform papillae in humans: a co-twin randomised controlled trial." British Journal of Nutrition 122, no. 11 (2019): 1212–20. http://dx.doi.org/10.1017/s0007114519002368.

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AbstractFatty acid taste (FAT) perception is involved in the regulation of dietary fat intake, where impaired FAT is associated with increased fatty food intake. There are a number of FAT receptors identified on human taste cells that are potentially responsible for FAT perception. Manipulating dietary fat intake, and in turn FAT perception, would elucidate the receptors that are associated with long-term regulation of FAT perception. The present study aimed to assess associations between diet-mediated changes to FAT receptors and FAT perception in humans. A co-twin randomised controlled trial
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4

Wathes, C. M., T. G. M. Demmers, N. Teer, et al. "Production responses of weaned pigs after chronic exposure to airborne dust and ammonia." Animal Science 78, no. 1 (2004): 87–97. http://dx.doi.org/10.1017/s135772980005387x.

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AbstractNine hundred and sixty weaned pigs were exposed for 5·5 weeks to controlled concentrations of airborne dust and ammonia in a single, multi-factorial experiment. Production and health responses were measured but only the former are reported here. The treatments were a dust concentration of either 1·2, 2·7, 5·1 or 9·9 mg/m3(inhalable fraction) and an ammonia concentration of either 0·6, 10·0, 18·8 or 37·0 p. p. m., which are representative of commercial conditions. The experiment was carried out over 2·5 years and pigs were used in eight batches, each comprising five lots of 24 pigs. Eac
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5

Hochhaus, Andreas, Martin C. Müller, Jerald Radich, et al. "Dasatinib-Associated Major Molecular Responses Are Rapidly Achieved in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Following Resistance, Suboptimal Response, or Intolerance on Imatinib." Blood 112, no. 11 (2008): 1095. http://dx.doi.org/10.1182/blood.v112.11.1095.1095.

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Abstract Dasatinib (SPRYCEL®) is a highly potent BCR-ABL inhibitor, with 325-fold higher potency than imatinib and a 16-fold higher potency than nilotinib in vitro. Across a series of phase II and III trials with more than 2 years of follow-up, dasatinib has demonstrated durable efficacy in patients with CML following resistance, suboptimal response, or intolerance to imatinib. Qualitative and quantitative assessment of BCR-ABL transcripts by RT-PCR is the most sensitive method for assessing minimal residual disease in patients with CML. In the treatment of patients with CML in the first-line
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6

ERSOY, Zeynep, Nedim ÇEKMEN, Aycan ÖZDEMİRKAN, Pınar ZEYNELOGLU, Adnan TORGAY, and Mehmet HABERAL. "Acute Kidney Injury After Liver Transplantation: Incidence, Risk Factors, and Outcomes." Cukurova Anestezi ve Cerrahi Bilimler Dergisi 6, no. 1 (2023): 1–11. http://dx.doi.org/10.36516/jocass.1225060.

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Introduction: Although numerous risk factors for acute kidney injury (AKI) have been identified, their cumulative impact remains unclear. This study aimed to identify perioperative risk factors for early post-transplant AKI on patients and outcomes and to predict AKI using clinical variables.
 Material and Methods: A single-center, retrospective cohort study involving 34 pediatric patients and 31 adults who underwent LT between 2015 and 2017.
 Results: AKI occurred in 16 (47%) pediatric patients during the first-week post-LT with stage 1, stage 2, and stage 3 AKI frequencies of 43.8,
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7

Harrowfield, Jack M., Raj Pal Sharma, Brian W. Skelton, and Allan H. White. "Structural Systematics of 2/4-Nitrophenoxide Complexes of Closed-Shell Metal Ions. III 2/4-Nitrophenoxides of Univalent Heavy Metals." Australian Journal of Chemistry 51, no. 8 (1998): 735. http://dx.doi.org/10.1071/c97100.

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Room-temperature single-crystal X-ray studies are recorded for 2- and 4-nitrophenoxide salts of silver(I) and thallium(I), M(2-np) and Tl(4-np) (anhydrous), and Ag(4-np).H2O. Ag(2-np) is monoclinic, P21/c, a 9·012(4), b 5·743(5), c 12·594(5) Å, β 104·34(4)°, Z = 4; conventional R on |F| was 0·042 for No 1378 independent ‘observed’ (I > 3σ(I)) reflections. Tl(2-np) is monoclinic, C2/c, a 27·250(3), b 3·712(1), c 15·147(3) Å, β 114·41(1)°, Z = 8, R 0·025 for No 1346. Ag(4-np).H2O is monoclinic, P21/a, a 5·613(6), b 13·191(7), c 9·844(5) Å, β 92·50(6)°, Z = 4, R 0 ·033 for No 622. Tl(4-np) is
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8

Rodriguez, Karla Baez, Nicole Torres Rivera, Janevi Rebernigg, et al. "PSUN146 Diabetes, Obesity, and Diabetes-Obesity Overlap Syndrome in Hospitalized Adult COVID-19 Patients: Comorbidity Dose is The Thing!" Journal of the Endocrine Society 6, Supplement_1 (2022): A365. http://dx.doi.org/10.1210/jendso/bvac150.758.

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Abstract Excess risk for mortality in hospitalized adults with COVID-19 has been linked to extant chronic conditions, especially obesity (Obes), diabetes (DM) or combination (ObesDM). We investigated dose-response interactions between Elixhauser Comorbidity Index (ECI) and comorbidity ensembles including Obes, DM, ObesDM or Control. Presentation demographics, putative COVID-19 severity markers, and administrative data including ICD-10 codes to measure ECI (AHRQ, v2022.1, 0-38 categories) were extracted under IRB exemption from electronic medical records. Youden's J statistic identified ECI35 p
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9

Плохіх, Віктор Володимирович. "Зв’язок копінг-поведінки з переживаннями плину часу у студентів". Insight: the psychological dimensions of society, № 9 (5 травня 2023): 72–93. http://dx.doi.org/10.32999/ksu2663-970x/2023-9-5.

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Сучасний студент усупереч суттєвому підвищеннюнавчального навантаження та загальному ускладненню життєдіяльності повинен бути здатним додолання стресових ситуацій і своєчасного виконання завдань. Метою дослідження є емпіричневизначення підґрунтя та особливостей для характерних зв’язків виборів варіантів копінг-поведінкиз переживаннями плину часу у студентів. Методи.Досліджуваними були 139 студентів університету.В емпіричному дослідженні використовувалисятакі стандартизовані тестові методики: “Копінг-поведінка в стресових ситуаціях”; шкала “Компетентність у часі” з тесту самоактуалізації особис
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10

Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics
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11

Black, H. J., and D. M. B. Chestnutt. "Effect of shearing and level of concentrate feeding on the performance of finishing lambs." Animal Science 54, no. 2 (1992): 221–28. http://dx.doi.org/10.1017/s0003356100036837.

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AbstractThe response of finishing Blackface lambs (mean initial live weight 29·6 kg) to shearing and level of concentrate supplementation on a silage-based diet was examined in two experiments. Silage intake decreased as concentrate level increased at mean rate of 0·13 and 0·26 g silage dry matter (DM) per g concentrate DM, in experiments 1 and 2 respectively, with no significant differences between unshorn and shorn lambs. Lambs gained 36, 97, 135, 193 and 224 g/day (s.e. 9·1; P < 0·001) in experiment 1 and 97,133,170,185 and 222 g/day (s.e. 9·9; P < 0·001) in experiment 2 when 0, 200,
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12

Steen, R. W. J. "A comparison of wheat and barley as supplements to grass silage for finishing beef cattle." Animal Science 56, no. 1 (1993): 61–67. http://dx.doi.org/10.1017/s0003356100006164.

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AbstractTwo randomized-block experiments were carried out to examine the relative value of wheat and barley as supplements to grass silage for finishing beef cattle. In each experiment unwilted, formic acid-treated silage was offered ad libitum and supplemented with 500 g soya-bean meal and 50 g minerals and vitamins to 44 12-month-old bulls for 157 and 172 days in experiments 1 and 2 respectively. Twelve of the animals also received 2·5 kg rolled spring barley (LB), 12 received 4·0 kg barley (HB) and 20 received 3·25 kg rolled wheat (W). For experiments 1 and 2 respectively the barley contain
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13

Kennedy, S. H., and C. Guilleminault. "P.2.c.013 Antidepressant efficacy of agomelatine 25-50 mg versus venlafaxine 75 -150 mg: two randomized, double blind studies." European Neuropsychopharmacology 16 (January 2006): S319—S320. http://dx.doi.org/10.1016/s0924-977x(06)70347-9.

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14

Trabelsi, Khaled, Kais el Abed, Stephen R. Stannard, Kamel Jammoussi, Khaled M. Zeghal, and Ahmed Hakim. "Effects of Fed- Versus Fasted-State Aerobic Training During Ramadan on Body Composition and Some Metabolic Parameters in Physically Active Men." International Journal of Sport Nutrition and Exercise Metabolism 22, no. 1 (2012): 11–18. http://dx.doi.org/10.1123/ijsnem.22.1.11.

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The aim of this study was to evaluate the effects of aerobic training in a fasted versus a fed state during Ramadan on body composition and metabolic parameters in physically active men. Nineteen men were allocated to 2 groups: 10 practicing aerobic training in a fasted state (FAST) and 9 training in an acutely fed state (FED) during Ramadan. All subjects visited the laboratory for a total of 4 sessions on the following occasions: 3 days before Ramadan (Bef-R), the 15th day of Ramadan; the 29th day of Ramadan (End-R), and 21 days after Ramadan. During each session, subjects underwent anthropom
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15

Swaminathan, Mahesh, Hussein A. Abbas, Guillermo Garcia-Manero, et al. "Treatment in Clinical Trials Could Potentially Overcome the Disparity in Outcomes of Patients with Acute Myeloid Leukemia from Disadvantaged Neighborhoods." Blood 144, Supplement 1 (2024): 3817. https://doi.org/10.1182/blood-2024-210779.

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Introduction Population-based studies from publicly available databases have shown a disparity in the outcomes of patients (pts) with acute myeloid leukemia (AML) based on their racial background. However, such studies are limited as several aspects of socioeconomic (SE) data, an independent prognostic factor, still need to be captured. Area Deprivation Index (ADI) is one of the most advanced SE tools, incorporating 17 SE factors to rank neighborhoods based on disadvantaged status (Powell et al. Forefront, 2023). This abstract, reports the largest cohort of pts with molecular, cytogenetic (CG)
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16

Bharathi, A., Selvaraj Mohana Roopan, Abdul Abdul Rahuman, and G. Rajakumar. "(E)-2-Benzylidene-7-chloro-9-phenyl-3,4-dihydroacridin-1(2H)-ones: synthesis and larvicidal activity." Research on Chemical Intermediates 41, no. 4 (2013): 2453–64. http://dx.doi.org/10.1007/s11164-013-1359-x.

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17

Upadhyah Amit A. "Analysis of One Best MCQS in Five Preuniversity Physiology Examinations." International Journal of Physiology 7, no. 4 (2019): 10–15. http://dx.doi.org/10.37506/ijop.v7i4.47.

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Objectives
 One-best MCQs (Multiple Choice Questions) is a popular form of assessment where the student selects the best possible answer from the options provided. The objective of this study was to analyze the MCQs used in preliminary examinations in terms of Difficulty Index, Differentiation Index and Distracter efficiency.
 Method
 Total 100 MCQ items with one correct option and three distracters were taken from past 5 years preuniversity examinations and analyzed for level of difficulty and power of discrimination. A total of 149, 156, 154, 156 and 148 students appeared for
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18

Bodkin, Stephan G., Margaret H. Rutherford, David R. Diduch, Stephen F. Brockmeier, and Joe M. Hart. "How Much Time Is Needed Between Serial “Return to Play” Assessments to Achieve Clinically Important Strength Gains in Patients Recovering From Anterior Cruciate Ligament Reconstruction?" American Journal of Sports Medicine 48, no. 1 (2019): 70–77. http://dx.doi.org/10.1177/0363546519886291.

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Background: Pass rates for return-to-play evaluations are alarmingly low for patients after anterior cruciate ligament reconstruction (ACLR). Since timing of return to play is a complicated decision, it is important that patients be given optimal time to realize meaningful improvements in strength that warrant additional testing. Purpose: To (1) compare outcomes among patients assessed at different time points after ACLR, (2) determine strength gains indicative of improvements in subjective function, and (3) determine the amount of time necessary to achieve meaningful strength gains. Study Des
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19

Aoki, Naomi J., Kylie Venardos, Nick Andrianopoulos, et al. "Use of Blood Components in Major Obstetric Hemorrhage: Preliminary Findings from the Australian and New Zealand Massive Transfusion Registry (ANZ-MTR)." Blood 124, no. 21 (2014): 1563. http://dx.doi.org/10.1182/blood.v124.21.1563.1563.

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Abstract Introduction: Major obstetric hemorrhage (MOH) can develop rapidly and, due to the unique characteristics of maternity patients, early recognition and management can be challenging. Use of blood components in MOH can be life-saving however there is uncertainty about optimal use of these products and the role of adjunctive therapies. The ANZ-MTR generates observational data on current transfusion management and outcomes in critically bleeding patients receiving massive transfusion (MT) across all clinical settings. This study aimed to describe the transfusion strategies used in the MOH
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20

Narita, Taichi, Hansani Madushika Abeywickrama, Marcello Otake Sato, et al. "Knowledge, attitudes, and practices regarding tick-borne diseases among an at-risk population living in Niigata prefecture, Japan." PLOS ONE 17, no. 6 (2022): e0270411. http://dx.doi.org/10.1371/journal.pone.0270411.

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Objective This study examined the knowledge, attitudes, and practices (KAP) of an at-risk population living in Niigata prefecture regarding tick-borne diseases (TBDs) and preventive strategies. Methods A cross-sectional questionnaire-based study was conducted to assess the KAP of the community. Results In total, 186 responses were received. Among the respondents, 130 (69·9%) were men, and the mean age was 51.1 (14·3). Nine (4·8%) respondents reported having experienced tick bites. Of the respondents, 44 (23.7%) knew about both scrub typhus and severe fever with thrombocytopenia syndrome, while
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21

Cheng, Vincent Chi-Chung, Kitty Sau-Chun Fung, Gilman Kit-Hang Siu, et al. "Nosocomial Outbreak of Coronavirus Disease 2019 by Possible Airborne Transmission Leading to a Superspreading Event." Clinical Infectious Diseases 73, no. 6 (2021): e1356-e1364. http://dx.doi.org/10.1093/cid/ciab313.

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Abstract Background Nosocomial outbreaks with superspreading of coronavirus disease 2019 due to a possible airborne transmission have not been reported. Methods Epidemiological analysis, environmental samplings, and whole-genome sequencing (WGS) were performed for a hospital outbreak. Results A superspreading event that involved 12 patients and 9 healthcare workers (HCWs) occurred within 9 days in 3 of 6 cubicles at an old-fashioned general ward with no air exhaust built within the cubicles. The environmental contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was
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22

Zang, Rongyu, Tingyan Shi, Rong Jiang, et al. "Dose-dense early postoperative intraperitoneal chemotherapy in ovarian cancer: Randomized, phase II trial." Journal of Clinical Oncology 37, no. 15_suppl (2019): 5514. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.5514.

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5514 Background: Dose-dense early postoperative intraperitoneal chemo (DD-EPIC) had been carried out in advanced ovarian cancer (OC) pts in China over the past three decades but it was not proved by a prospective study. This trial was designed to confirm the benefit of DD-EPIC in delaying progression and improving survival. Methods: In a multicenter, phase 2 trial, pts with FIGO IIIC-IV OC and optimal debulking surgery (residual disease ≤1cm) were randomly allocated to receive 4 doses of weekly DD-EPIC with cisplatin (50mg/m2) and etoposide (100mg/m2) followed by 6 cycles of intravenous (iv) c
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23

Tempero, Margaret, William Plunkett, Veronique Ruiz van Haperen, et al. "Randomized Phase II Comparison of Dose-Intense Gemcitabine: Thirty-Minute Infusion and Fixed Dose Rate Infusion in Patients With Pancreatic Adenocarcinoma." Journal of Clinical Oncology 21, no. 18 (2003): 3402–8. http://dx.doi.org/10.1200/jco.2003.09.140.

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Purpose: To conduct a randomized phase II trial of dose-intense gemcitabine using a standard 30-minute infusion or the fixed dose rate (FDR) infusion (10 mg/m2/min) in patients with pancreatic adenocarcinoma. Patients and Methods: In this prospective trial, patients with locally advanced and metastatic pancreatic adenocarcinoma were treated with 2,200 mg/m2 gemcitabine over 30 minutes (standard arm) or 1,500 mg/m2 gemcitabine over 150 minutes (FDR arm) on days 1, 8, and 15 of every 4-week cycle. The primary end point of this trial was time to treatment failure. Secondary end points included ti
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24

Parker, Pablo M., Ryotaro Nakamura, Vinod Pullarket, et al. "Analysis of Predictive Power of Prednisone Dose at 3 Months of Treatment on CGVHD Prognosis." Blood 110, no. 11 (2007): 1975. http://dx.doi.org/10.1182/blood.v110.11.1975.1975.

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Abstract Current CGVHD prognostic and staging systems are still undergoing development and have identified plt count; CGVHD types progressive(P), quiescent(Q), de novo(DN); KPS, and GI involvement as significant risk factors affecting outcome. A simple reproducible staging system such as used for AGVHD to apply in clinical trials is still lacking. We evaluated whether the PSE dose required to control CGVHD at 3 months from diagnosis would have a prognostic effect on survival and in and of itself serve as a criteria for secondary intervention or investigational therapy. We hypothesized that by
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25

Kameshkov, A. V., A. A. Gaile, N. V. Kuzichkin, D. A. Sladkovskiy, K. V. Semikin, and A. R. Vorobyova. "Extraction Refinement of Light and Heavy Gas Oils of Delayed Coking." Oil and Gas Technologies 139, no. 2 (2022): 3–9. http://dx.doi.org/10.32935/1815-2600-2022-139-2-3-9.

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A description of the results of the extraction purification of light gas oil of delayed coking with N, N-dimethylformamide and heavy gas oil with N-methylpyrrolidone is given at mass ratios of extractants to feedstock (0.3–0.6):1. The degree of extraction of nitrogenous, sulfur components and mono-, di-, tri -arens is estimated.
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26

Undas, Anetta, Kathleen Brummel, Jacek Musial, Kenneth G. Mann, and Andrew Szczeklik. "Blood coagulation at the site of microvascular injury: effects of low-dose aspirin." Blood 98, no. 8 (2001): 2423–31. http://dx.doi.org/10.1182/blood.v98.8.2423.

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Abstract The sequence of coagulant reactions in vivo following vascular injury is poorly characterized. Using quantitative immunoassays, the time courses were evaluated for activation of prothrombin, factor (F)V, FXIII, fibrinogen (Fbg) cleavage, and FVa inactivation in bleeding-time blood collected at 30-second intervals from 12 healthy subjects both before and after aspirin ingestion. Prothrombin decreased at a maximum rate of 14.2 ± 0.6 nM per second to 10% of initial values at the end of bleeding. Significant amounts of α-thrombin B chain appeared rapidly at 90 seconds of bleeding and incr
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27

Kaye, S. B., J. Paul, J. Cassidy, et al. "Mature results of a randomized trial of two doses of cisplatin for the treatment of ovarian cancer. Scottish Gynecology Cancer Trials Group." Journal of Clinical Oncology 14, no. 7 (1996): 2113–19. http://dx.doi.org/10.1200/jco.1996.14.7.2113.

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PURPOSE In 1992, we reported the first results of a randomized study in ovarian cancer, comprising two doses of cisplatin and indicated a significant difference (P = .0008) in median survival. Four years later, we now describe the results of this trial. PATIENTS AND METHODS After a median follow-up of 4 years and 9 months, 115 of 159 cases of advanced ovarian cancer, originally randomized to receive six cycles of cyclophosphamide 750 mg/m2 and either a high dose (HD) of 100 mg/m2 cisplatin or a low dose (LD) of 50 mg/m2 (LD) cisplatin, have now died. RESULTS The overall survival for HD and LD
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Ball, Lynne M., Maria-Ester Bernardo, Helene Roelofs, et al. "Co-Transplantation of HLA-Haploidentical, Bone Marrow Derived Mesenchymal Stem Cells Prevents Graft Failure and Improves Hematological Recovery in T-Cell Depleted Haploidentical Stem Cell Transplantation." Blood 110, no. 11 (2007): 3073. http://dx.doi.org/10.1182/blood.v110.11.3073.3073.

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Abstract Haploidentical CD34+ purified peripheral blood stem cell transplantation (PBSCT) is associated with an increased risk of graft failure/rejection. Animal models suggest that MSCs may promote engraftment after hematopoietic stem cell transplanation (HSCT) but there role in overcoming graft failure in human HSCT is still unclear. We recently reported our initial findings in 13 children receiving MSCs in conjunction with haplo-PBSCT. Here we report our extended series of 20 patients, now including those with MDS known to have an increased risk of rejection. MSCs were isolated from marrow
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Battaglin, Francesca, Joanne Xiu, Yasmine Baca, et al. "Comprehensive molecular profiling of IDH1/2 mutant biliary cancers (BC)." Journal of Clinical Oncology 38, no. 4_suppl (2020): 479. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.479.

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479 Background: Isocitrate dehydrogenases (IDH) play a key role in energetic metabolism and IDH mutations (mut) promote oncogenesis via epigenetic and genetic changes. Data addressing the molecular contexture of IDH1/2 mut in BC are lacking. We aimed to characterize the molecular profile of IDH1/2 mutant (mIDH) GI cancers with a focus on BC. Methods: 27954 GI cancer samples collected between August 2000 and July 2019 were included: 2057 BC (1159 ICC, 277 extrahepatic CC, 573 gallbladder, 48 unspecified CC), 13807 colorectal, 4183 gastric/esophageal, 3060 other. Samples were analyzed using Next
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Zhang, Chuan-Bao, Zhao-Shi Bao, Hong-Jun Wang, et al. "Correlation of IDH1/2 mutation with clinicopathologic factors and prognosis in anaplastic gliomas: a report of 203 patients from China." Journal of Cancer Research and Clinical Oncology 140, no. 1 (2013): 45–51. http://dx.doi.org/10.1007/s00432-013-1519-9.

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31

Steen, R. W. J. "The effect of supplementing silage-based diets with soya bean and fish meals for finishing beef cattle." Animal Science 46, no. 1 (1988): 43–51. http://dx.doi.org/10.1017/s0003356100003093.

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ABSTRACTTwo experiments have been carried out to examine the effects on the intake and performance of finishing beef cattle of supplementing grass silages (perennial ryegrass) of medium and high digestibility (MD and HD respectively) with either extracted soya-bean meal or fish meal. In each experiment, the two silages were supplemented with (1) barley (107 g crude protein (CP) per kg dry matter (DM)), (2) a mixture of barley and soya-bean meal (187 g CP per kg DM) and (3) a mixture of barley and fish meal (182 g CP per kg DM) in a 2 × 3 factorial design. The MD silages were supplemented with
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Nurbaeva, K., T. Reshetnyak, F. Cheldieva, M. Cherkasova, E. Samarkina, and A. Lila. "AB0116 NEW INFLAMMATORY MARKERS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND ANTIPHOSPHOLIPID SYNDROME." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1188.1–1189. http://dx.doi.org/10.1136/annrheumdis-2022-eular.1331.

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BackgroundThromboinflammation is a pathological process that is associated with uncontrolled inflammation, leading to hypercoagulability and thrombotic complications. Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are prototypical chronic thromboinflammatory diseases. Neutrophils are important cells in the development of systemic inflammation and thrombosis. Neutrophil reactivity (NEUT-RI), neutrophil granularity (NEUT-GI), immature granulocytes (IG), and neutrophil-to-lymphocyte ratio (NLR) are considered as inflammatory markers.ObjectivesTo determine the role of param
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33

Matsuyama, Jin, Hisato Kawakami, Kazumasa Fujitani, et al. "Comparing five-weekly S-1 plus cisplatin with tri-weekly capecitabine plus cisplatin in patients with HER2-negative recurrent gastric cancer after S-1 adjuvant therapy or chemotherapy naïve advanced gastric cancer: A pooled analysis of HERBIS-2 (OGSG 1103) and HERBIS-4A (OGSG 1105) trials." Journal of Clinical Oncology 38, no. 4_suppl (2020): 379. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.379.

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379 Background: HERBIS-2 trial was a phase II trial where S-1 plus cisplatin (SP) and capecitabine plus cisplatin (XP) were compared in recurrent HER2 negative gastric cancer (GC) patients with recurrence free interval (RFI) by S-1containing adjuvant of ≥ 6 months. We performed pooled analyses of HERBIS-2 and HERBIS-4A trial where SP and XP were compared in chemotherapy-naive HER2 negative gastric cancer (GC) patients as these trials being identical. Methods: Both HERBIS-2 and 4A trials, patients were randomly assigned to receive either SP (S-1 at 40–60 mg twice daily for 21 days plus cisplati
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34

Harland, Janice I., and Lynne E. Garton. "Whole-grain intake as a marker of healthy body weight and adiposity." Public Health Nutrition 11, no. 6 (2008): 554–63. http://dx.doi.org/10.1017/s1368980007001279.

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AbstractObjectiveTo review evidence relating to the consumption of whole grains and healthy body weight (BW).DesignSystematic review and analysis of observational studies reporting whole-grain consumption and measures of BW and adiposity, including the effect on macronutrient intakes and lifestyle factors.SettingMedline and other databases were searched for the period 1990 to 2006 to produce a full reference list; observational studies were retained for further analysis if they included an appropriate control group and reported whole-grain intake and body mass index (BMI) or a measure of adipo
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Lozano, Miguel, Ana Galan, Roberto Mazzara, Laurence Corash, and Gines Escolar. "Leucocyte-Reduced Buffy Coat Platelet Concentrates (BCPC) Treated with INTERCEPT™ Stored up to 7 Days: Hemostatic Function in a Whole Blood Flow System." Blood 106, no. 11 (2005): 956. http://dx.doi.org/10.1182/blood.v106.11.956.956.

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Abstract Background: The risk of bacterial growth has limited the shelf life of platelet concentrates (PC) to 5 days. Modern platelet storage containers facilitate storage for up to 7 days, if bacterial contamination is prevented. INTERCEPT (Baxter, La Chatre, France; Cerus, Concord, CA) photochemical treatment (PCT) for pathogen reduction based on amotosalen (150μM) and UVA illumination (3 J/cm2) inactivates high titers of bacteria in PC (Transfusion2004; 44: 1496–1504). Adhesion and aggregation of platelets to injured vascular surfaces are critical aspects of platelet hemostatic function. In
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Barreira, S. C., A. R. Cruz-Machado, A. L. Fernandes, et al. "AB1145 PRESCRIPTION PATTERNS AND DISEASE ACTIVITY IN PORTUGUESE WOMEN OF CHILDBEARING AGE WITH RHEUMATOID ARTHRITIS, PSORIATIC ARTHRITIS, ANKYLOSING SPONDYLITIS AND JUVENILE IDIOPATHIC ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1862.1–1863. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1976.

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Background:Disease activity (DA) at conception is one of the main predictors of pregnancy outcomes in women of childbearing age (WoCBA) with rheumatic diseases. Teratogenicity and unawareness about pregnancy compatibility of some disease-modifying anti-rheumatic drugs might limit the choice of treatment in WoCBA.Objectives:To assess differences in prescription patterns between WoCBA with rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS) and juvenile idiopathic arthritis (JIA) and comparator groups, namely postmenopausal women (PMW) and age-matched men. Evaluate
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De Agustin, J. J., G. Añez, D. Reina-Sanz, et al. "AB1116 APREMILAST IN PSORIATIC ARTHRITIS. ULTRASOUND ANALYSIS (JOINT-ENTHESES-UNGUEAL INDEX) OF THE EFFICACY AND VARIABLES CORRELATION STUDY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1787–88. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1397.

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BackgroundWe conducted a study using ultrasonography (US) to evidence inflammatory changes (joint-enthesis-ungueal) in active PsA (aPsA) patients who started Apremilast (A) in clinical practice.ObjectivesObtain a 20, 50, 70 % reduction in the US index (UIC) at 12 months, and study correlation between variables.MethodsPhase IV, multicenter, prospective and open-label clinical trialconductedin 9 centresfrom 2018 to 2021. All patients signed the informed consent. Approval by the ethical committee was obtained, code PSA-PI-006421. PsA patients (≥ 2 swollen joints), ≥ 2 joint US synovitis and ≥ 1 U
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Kuznetsov, T. Y., A. N. Pashtaev, T. A. Khalilva, and D. N. Sushentsova. "Shifting the diameter zone of intrastromal corneal segment implantation for refractive purposes." Clinical cases in ophthalmology, no. 2 (November 2, 2023): 17–18. http://dx.doi.org/10.25276/2949-4494-2023-2-17-18.

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Цель. Представить клинический случай смещения зоны диаметра имплантации интрастромального роговичного сегмента с рефракционной целью. Методы. Мужчина Е., 28 лет, предъявлял жалобы на снижение остроты зрения, быструю утомляемость при зрительной нагрузке левого глаза. Из анамнеза известно: в 2019 г. при обращении в одну из московских клиник был выставлен диагноз – кератоконус 2-й стадии левого глаза. Пациенту была проведена интрастромальная кератопластика, а затем через 1 год – кросслинкинг роговицы левого глаза. В нашей клинике пациенту был проведен стандартный объем диагностический исследовани
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Sakti, B. Retno Pratiwi. "PENGARUH LOKASI DAN KUALITAS PELAYANAN TERHADAP KEPUASAN KONSUMEN INDOMARET SOLEH ISKANDAR KM 9 BOGOR." JURNAL ILMIAH MANAJEMEN DAN KEWIRAUSAHAAN 3, no. 1 (2024): 26–42. https://doi.org/10.71277/epsp7r29.

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Penelitian ini bertujuan untuk mengetahui pengaruh dari lokasi dan kualitas pelayanan terhadap kepuasan para konsumen Indomaret Soleh Iskandar KM 9 Bogor. Responden yang diteliti adalah 109 konsumen yang berbelanja di Indomaret Soleh Iskandar KM 9 Bogor. Berdasarkan data yang telah dikumpulkan dan serangkaian pengujian yang dilakukan dengan metode analisis uji t, koefisien determinasi, korelasi, regresi, maka didapat kesimpulan sebagai berikut: 1) Semua instrumen variabel Lokasi (X1), Kualitas Pelayanan (X2) serta Kepuasan Konsumen (Y) mempunyai nilai CITC lebih besar dari 0,3. Hal ini menunju
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Lang, Brittany, Zachary Yukio Kerr, Samuel R. Walton, et al. "2 The Longitudinal Relationship Between Concussion History, Years of Football Participation, and Alcohol Use Among Former National Football League (NFL) Players: an NFL-LONG Study." Journal of the International Neuropsychological Society 29, s1 (2023): 114–15. http://dx.doi.org/10.1017/s1355617723002060.

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Objective:It has been posited that alcohol use may confound the association between greater concussion history and poorer neurobehavioral functioning. However, while greater alcohol use is positively correlated with neurobehavioral difficulties, the association between alcohol use and concussion history is not well understood. Therefore, this study investigated the cross-sectional and longitudinal associations between cumulative concussion history, years of contact sport participation, and health-related/psychological factors with alcohol use in former professional football players across mult
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41

Yam, Clinton, Miral Patel, Jia Sun, et al. "Early on-treatment (on-Rx) tumor volume reduction (TVR) to predict response to the KEYNOTE-522 (KN-522) regimen in early stage triple negative breast cancer (TNBC)." Journal of Clinical Oncology 43, no. 16_suppl (2025): 592. https://doi.org/10.1200/jco.2025.43.16_suppl.592.

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592 Background: Monitoring clinical response by breast ultrasound (US) during neoadjuvant therapy is considered standard of care. We previously demonstrated that suboptimal on-Rx TVR after neoadjuvant doxorubicin and cyclophosphamide (AC) predicts non-pCR after sequential taxane-based chemo. However, it is unknown if on-Rx TVR has the similar predictive value in pts receiving the KN-522 chemo-immunotherapy regimen. Methods: Pts with early stage TNBC planned to receive the KN-522 regimen were enrolled on the prospective ARTEMIS trial (NCT02276443). Breast US was performed at baseline and after
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42

van Wassenaer, Elsa A., Floris A. E. de Voogd, Rick R. van Rijn, et al. "Bowel ultrasound measurements in healthy children — systematic review and meta-analysis." Pediatric Radiology 50, no. 4 (2019): 501–8. http://dx.doi.org/10.1007/s00247-019-04567-2.

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Abstract Background Ultrasound (US) is a noninvasive method of assessing the bowel that can be used to screen for bowel pathology, such as Inflammatory Bowel Disease, in children. Knowledge about US findings of the bowel in healthy children is important for interpreting US results in cases where disease is suspected. Objective To assess the bowel wall thickness in different bowel segments in healthy children and to assess differences in bowel wall thickness among pediatric age categories. Materials and methods We conducted a systematic search in the PubMed, Embase, Cochrane, and CINAHL databas
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43

Patiag, D., X. Qu, S. Gray, et al. "Possible interactions between angiotensin II and insulin: effects on glucose and lipid metabolism in vivo and in vitro." Journal of Endocrinology 167, no. 3 (2000): 525–31. http://dx.doi.org/10.1677/joe.0.1670525.

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Angiotensin II (ANGII) increases insulin sensitivity in diabetic and non-diabetic subjects, even at subpressor doses, and because there is 'crosstalk' between ANGII and insulin-signaling pathways the underlying mechanism may not be due solely to changes in regional blood flow. A series of experimental studies was undertaken to evaluate the effects of ANGII on glucose and lipid metabolism in vivo and in vitro. Groups of fructose-fed, insulin-resistant Sprague-Dawley (SD) rats were pre-treated with 0.3 mg/kg per day of the AT(1)-receptor antagonist L-158 809 (n=16), or vehicle (n=16), by oral ga
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44

Dolezal, J. "Radiation exposure of the staff at the therapeutic and diagnostic nuclear medicine department." Nuklearmedizin 47, no. 04 (2008): 175–77. http://dx.doi.org/10.3413/nukmed-0163.

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SummaryAim: To assess a radiation exposure and the quality of radiation protection concerning a nuclear medicine staff at our department as a six-year retrospective study. Therapeutic radionuclides such as 131I, 153Sm, 186Re, 32P, 90Y and diagnostic ones as a 99mTc, 201Tl, 67Ga, 111In were used. Material, method: The effective dose was evaluated in the period of 2001–2006 for nuclear medicine physicians (n = 5), technologists (n = 9) and radiopharmacists (n = 2). A personnel film dosimeter and thermoluminescent ring dosimeter for measuring (1-month periods) the personal dose equivalent Hp(10)
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Awasthi, Shally, Narayan U. Reddy, Monjori Mitra, et al. "Micronutrient-fortified infant cereal improves Hb status and reduces iron-deficiency anaemia in Indian infants: an effectiveness study." British Journal of Nutrition 123, no. 7 (2020): 780–91. http://dx.doi.org/10.1017/s0007114519003386.

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AbstractAnaemia affects approximately 69 % of Indian children aged 6–12 months, with Fe deficiency (ID) being a common cause. The effectiveness of micronutrient-fortified infant cereal in improving Fe status and neurodevelopment was evaluated in non-anaemic and mildly anaemic Indian infants. An intervention group (IC) enrolled at age 6 months consumed 50 g/d of rice-based cereal providing 3·75 mg Fe/d as ferrous fumarate for 6 months (n 80) and was compared with a matched static cross-sectional control group (CG) without intervention enrolled at age 12 months (n 80). Mean Hb was higher in IC (
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Jabban, Yazan, Rong He, Kurt Bessonen, et al. "Clinical Characteristics and Prognostic Significance of Co-Mutated SETBP1/GATA2 Myeloid Neoplasms." Blood 144, Supplement 1 (2024): 6700. https://doi.org/10.1182/blood-2024-201128.

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Background: SETBP1 gene, located on 18q12.3, is a major oncogene in myeloid neoplasms. GATA2 gene, located on 3q21, is one of the six GATA transcription factors regulating gene expression via two conserved zinc finger domains (ZF). Previous data suggested that in patients with germline GATA2 mutation (m), acquisition of a somatic SETBP1 mutation (m) was associated with leukemic transformation among patients with excess blast MDS and CMML. Aim: To study the characteristics of patients with somatic SETBP1-GATA2 mutated myeloid neoplasms. Methods: This study is a retrospective study at Mayo Clini
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Fischer, A., B. Seiser, M. Stocker Waldhuber, C. Mitterer, and J. Abermann. "Tracing glacier changes in Austria from the Little Ice Age to the present using a lidar-based high-resolution glacier inventory in Austria." Cryosphere 9, no. 2 (2015): 753–66. http://dx.doi.org/10.5194/tc-9-753-2015.

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Abstract. Glacier inventories provide the basis for further studies on mass balance and volume change, relevant for local hydrological issues as well as for global calculation of sea level rise. In this study, a new Austrian glacier inventory has been compiled, updating data from 1969 (GI 1) and 1998 (GI 2) based on high-resolution lidar digital elevation models (DEMs) and orthophotos dating from 2004 to 2012 (GI 3). To expand the time series of digital glacier inventories in the past, the glacier outlines of the Little Ice Age maximum state (LIA) have been digitalized based on the lidar DEM a
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He, Xin, Kyriakie Sarafoglou, Patricia Y. Fechner, et al. "Changes in Adrenal and Gonadal Androgens After 14-Day Treatment With CRF1 Receptor Antagonist, Crinecerfont (NBI-74788), in Men With Classic 21-Hydroxylase Deficiency." Journal of the Endocrine Society 5, Supplement_1 (2021): A78. http://dx.doi.org/10.1210/jendso/bvab048.157.

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Abstract Background: Congenital adrenal hyperplasia due to classic 21-hydroxylase deficiency (21OHD) causes cortisol insufficiency and androgen excess. A phase 2 trial of crinecerfont, a CRF1 receptor antagonist, in 18 adults with 21OHD showed prominent decreases in ACTH, 17-hydroxyprogesterone, and androstenedione (A4), and in women, testosterone (T), after 14 days of treatment. In men with 21OHD, T derives from both adrenals and testes; in poor disease control, A4/T ratio is elevated due to disproportionately increased adrenal A4 production and decreased testicular T production. We sought to
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Dela Cruz, Z., C. Hou, R. F. Martinez-Gazoni, R. J. Reeves та M. W. Allen. "Performance of in situ oxidized platinum/iridium alloy Schottky contacts on (001), ( 2¯01), and (010) β-Ga2O3". Applied Physics Letters 120, № 8 (2022): 083503. http://dx.doi.org/10.1063/5.0080652.

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The performance of β-Ga2O3 Schottky contacts (SCs) fabricated using amorphous, intentionally oxidized platinum–iridium alloys was investigated as a function of alloy composition and β-Ga2O3 crystal orientation. PtyIr(1−y)Ox SCs with Pt fractions of y = 0.8, 0.5, and 0.3 were deposited on (001), ([Formula: see text]), and (010) single-crystal β-Ga2O3 substrates via the reactive rf and dc co-sputtering of Pt and Ir targets using oxygen–argon plasmas. In each case, the PtyIr(1−y)Ox SCs were highly rectifying with current rectification ratios (at ±3 V) of 11/10/9 orders of magnitude (at 300 K) for
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Lebus, George F., Karen K. Briggs, Grant J. Dornan, Shannen McNamara, and Marc J. Philippon. "Acetabular Labral Reconstruction: Development of a Tool to Predict Outcomes." American Journal of Sports Medicine 46, no. 13 (2018): 3119–26. http://dx.doi.org/10.1177/0363546518796838.

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Background: Acetabular labral reconstruction has demonstrated good results for labral lesions not amenable to labral repair. Purpose: To determine the predictors of outcomes at a minimum 2 years after labral reconstruction. Study Design: Case series; Level of evidence, 4. Methods: Patients included in the study underwent labral reconstruction with a minimum 2-year follow-up. The primary outcome variable was the Hip Outcome Score–Activities of Daily Living (HOS-ADL). Secondary outcome measures included the 12-item Short Form Health Survey physical component summary (SF-12 PCS) and patient satis
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