Academic literature on the topic '159.9.016.12 (043.2)'

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Journal articles on the topic "159.9.016.12 (043.2)"

1

Martins, P. A., and A. L. Sawaya. "Evidence for impaired insulin production and higher sensitivity in stunted children living in slums." British Journal of Nutrition 95, no. 5 (2006): 996–1001. http://dx.doi.org/10.1079/bjn20061754.

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The objective of the present study was to investigate the changes in glucose and insulin metabolism in nutritionally stunted children that can be involved in the appearance of chronic diseases in adulthood. For this purpose, sixty-one children were selected, thirty-five boys and twenty-six girls, residents of slums in S˜o Paulo, Brazil. The children were classified according to the height-for-age as stunted (1·5 Z-score; n 21) or non-stunted (≥1·5 Z-score; n 40). The glucose and insulin plasma levels were determined and, from these values, the indexes that evaluate the pancreatic ·-cell functi
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2

Bussel, James B., Allison M. Schindler, and Elliott B. Grossbard. "R935788: A Phase II, Single Center, Open Label, Efficacy and Safety, Ascending Dose, Pilot Study for the Treatment of Adult Immune Thrombocytopenic Purpura (ITP)." Blood 110, no. 11 (2007): 1310. http://dx.doi.org/10.1182/blood.v110.11.1310.1310.

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Abstract Syk kinase is central to FcR and B-cell signaling in inflammatory cells. By inhibiting syk, and thereby IgG signaling, R788 (a small molecule prodrug for biologically active R406), inhibits the downstream activation of mast cells, macrophages and B-cells. (Braselmann S. Pharm Exp Ther. 2006). Preclinical study showed that R788 minimized thrombocytopenia in mice treated with anti-platelet antibodies (Crow, A.R. Blood 2005). In this study, adult, refractory ITP patients (pts) were treated with escalating doses of R788 in cohorts of ≥3 pts to evaluate safety and efficacy. After a cohort
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3

Hochhaus, Andreas, Martin C. Müller, Jerald Radich, et al. "Dasatinib-Associated Major Molecular Responses Are Rapidly Achieved in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Following Resistance, Suboptimal Response, or Intolerance on Imatinib." Blood 112, no. 11 (2008): 1095. http://dx.doi.org/10.1182/blood.v112.11.1095.1095.

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Abstract Dasatinib (SPRYCEL®) is a highly potent BCR-ABL inhibitor, with 325-fold higher potency than imatinib and a 16-fold higher potency than nilotinib in vitro. Across a series of phase II and III trials with more than 2 years of follow-up, dasatinib has demonstrated durable efficacy in patients with CML following resistance, suboptimal response, or intolerance to imatinib. Qualitative and quantitative assessment of BCR-ABL transcripts by RT-PCR is the most sensitive method for assessing minimal residual disease in patients with CML. In the treatment of patients with CML in the first-line
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4

Wathes, C. M., T. G. M. Demmers, N. Teer, et al. "Production responses of weaned pigs after chronic exposure to airborne dust and ammonia." Animal Science 78, no. 1 (2004): 87–97. http://dx.doi.org/10.1017/s135772980005387x.

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AbstractNine hundred and sixty weaned pigs were exposed for 5·5 weeks to controlled concentrations of airborne dust and ammonia in a single, multi-factorial experiment. Production and health responses were measured but only the former are reported here. The treatments were a dust concentration of either 1·2, 2·7, 5·1 or 9·9 mg/m3(inhalable fraction) and an ammonia concentration of either 0·6, 10·0, 18·8 or 37·0 p. p. m., which are representative of commercial conditions. The experiment was carried out over 2·5 years and pigs were used in eight batches, each comprising five lots of 24 pigs. Eac
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5

Harrowfield, Jack M., Raj Pal Sharma, Brian W. Skelton, and Allan H. White. "Structural Systematics of 2/4-Nitrophenoxide Complexes of Closed-Shell Metal Ions. III 2/4-Nitrophenoxides of Univalent Heavy Metals." Australian Journal of Chemistry 51, no. 8 (1998): 735. http://dx.doi.org/10.1071/c97100.

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Room-temperature single-crystal X-ray studies are recorded for 2- and 4-nitrophenoxide salts of silver(I) and thallium(I), M(2-np) and Tl(4-np) (anhydrous), and Ag(4-np).H2O. Ag(2-np) is monoclinic, P21/c, a 9·012(4), b 5·743(5), c 12·594(5) Å, β 104·34(4)°, Z = 4; conventional R on |F| was 0·042 for No 1378 independent ‘observed’ (I > 3σ(I)) reflections. Tl(2-np) is monoclinic, C2/c, a 27·250(3), b 3·712(1), c 15·147(3) Å, β 114·41(1)°, Z = 8, R 0·025 for No 1346. Ag(4-np).H2O is monoclinic, P21/a, a 5·613(6), b 13·191(7), c 9·844(5) Å, β 92·50(6)°, Z = 4, R 0 ·033 for No 622. Tl(4-np) is
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6

Steen, R. W. J. "A comparison of wheat and barley as supplements to grass silage for finishing beef cattle." Animal Science 56, no. 1 (1993): 61–67. http://dx.doi.org/10.1017/s0003356100006164.

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AbstractTwo randomized-block experiments were carried out to examine the relative value of wheat and barley as supplements to grass silage for finishing beef cattle. In each experiment unwilted, formic acid-treated silage was offered ad libitum and supplemented with 500 g soya-bean meal and 50 g minerals and vitamins to 44 12-month-old bulls for 157 and 172 days in experiments 1 and 2 respectively. Twelve of the animals also received 2·5 kg rolled spring barley (LB), 12 received 4·0 kg barley (HB) and 20 received 3·25 kg rolled wheat (W). For experiments 1 and 2 respectively the barley contain
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7

Cheng, Vincent Chi-Chung, Kitty Sau-Chun Fung, Gilman Kit-Hang Siu, et al. "Nosocomial Outbreak of Coronavirus Disease 2019 by Possible Airborne Transmission Leading to a Superspreading Event." Clinical Infectious Diseases 73, no. 6 (2021): e1356-e1364. http://dx.doi.org/10.1093/cid/ciab313.

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Abstract Background Nosocomial outbreaks with superspreading of coronavirus disease 2019 due to a possible airborne transmission have not been reported. Methods Epidemiological analysis, environmental samplings, and whole-genome sequencing (WGS) were performed for a hospital outbreak. Results A superspreading event that involved 12 patients and 9 healthcare workers (HCWs) occurred within 9 days in 3 of 6 cubicles at an old-fashioned general ward with no air exhaust built within the cubicles. The environmental contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was
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8

Ball, Lynne M., Maria-Ester Bernardo, Helene Roelofs, et al. "Co-Transplantation of HLA-Haploidentical, Bone Marrow Derived Mesenchymal Stem Cells Prevents Graft Failure and Improves Hematological Recovery in T-Cell Depleted Haploidentical Stem Cell Transplantation." Blood 110, no. 11 (2007): 3073. http://dx.doi.org/10.1182/blood.v110.11.3073.3073.

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Abstract Haploidentical CD34+ purified peripheral blood stem cell transplantation (PBSCT) is associated with an increased risk of graft failure/rejection. Animal models suggest that MSCs may promote engraftment after hematopoietic stem cell transplanation (HSCT) but there role in overcoming graft failure in human HSCT is still unclear. We recently reported our initial findings in 13 children receiving MSCs in conjunction with haplo-PBSCT. Here we report our extended series of 20 patients, now including those with MDS known to have an increased risk of rejection. MSCs were isolated from marrow
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9

Lebus, George F., Karen K. Briggs, Grant J. Dornan, Shannen McNamara, and Marc J. Philippon. "Acetabular Labral Reconstruction: Development of a Tool to Predict Outcomes." American Journal of Sports Medicine 46, no. 13 (2018): 3119–26. http://dx.doi.org/10.1177/0363546518796838.

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Background: Acetabular labral reconstruction has demonstrated good results for labral lesions not amenable to labral repair. Purpose: To determine the predictors of outcomes at a minimum 2 years after labral reconstruction. Study Design: Case series; Level of evidence, 4. Methods: Patients included in the study underwent labral reconstruction with a minimum 2-year follow-up. The primary outcome variable was the Hip Outcome Score–Activities of Daily Living (HOS-ADL). Secondary outcome measures included the 12-item Short Form Health Survey physical component summary (SF-12 PCS) and patient satis
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10

Undas, Anetta, Kathleen Brummel, Jacek Musial, Kenneth G. Mann, and Andrew Szczeklik. "Blood coagulation at the site of microvascular injury: effects of low-dose aspirin." Blood 98, no. 8 (2001): 2423–31. http://dx.doi.org/10.1182/blood.v98.8.2423.

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Abstract The sequence of coagulant reactions in vivo following vascular injury is poorly characterized. Using quantitative immunoassays, the time courses were evaluated for activation of prothrombin, factor (F)V, FXIII, fibrinogen (Fbg) cleavage, and FVa inactivation in bleeding-time blood collected at 30-second intervals from 12 healthy subjects both before and after aspirin ingestion. Prothrombin decreased at a maximum rate of 14.2 ± 0.6 nM per second to 10% of initial values at the end of bleeding. Significant amounts of α-thrombin B chain appeared rapidly at 90 seconds of bleeding and incr
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