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Journal articles on the topic '159.922.1 (043.2)'

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Published: 30 May 2022

Last updated: 31 July 2025

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1

Elliot, A. J., M. P. Chenier, and D. C. Ouellette. "Radiolysis studies on the corrosion inhibitors 1 -hexyn-3-ol, cinnamonitrile, and 1,3-diethyl-2-thiourea." Canadian Journal of Chemistry 73, no. 12 (1995): 2137–42. http://dx.doi.org/10.1139/v95-264.

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In this publication we report: (i) the rate constants for reaction of the hydrated electron with 1-hexyn-3-ol ((8.6 ± 0.3) × 108 dm3 mol−1 s−1 at 18 °C), cinnamonitrile ((2.3 ± 0.2) × 1010 dm3 mol−1 s−1 at 20 °C), and 1,3-diethyl-2-thiourea ((3.5 ± 0.3) × 108 dm3 mol−1 s−1 at 22 °C). For cinnamonitrile and diethylthiourea, the temperature dependence up to 200 °C and 150 °C, respectively, is also reported; (ii) the rate constants for the reaction of the hydroxyl radical with 1-hexyn-3-ol ((5.5 ± 0.5) × 109 dm3 mol−1 s−1 at 20 °C), cinnamonitrile ((9.2 ± 0.3) × 109 dm3 mol−1 s−1 at 21 °C), and d

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Hernández-Cruz, B., M. J. Miranda García, J. Barrera, et al. "AB1030 PATIENT CARE AT THE FRACTURE LIAISON SERVICE REDUCE THE GAP IN THE TREATMENT OF OSTEOPOROSIS BETWEEN MEN AND WOMEN." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1638–39. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4150.

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BackgroundOsteoporosis (OP) between men and women is different,and the way it is treated also differs. In men, the gap in clinical care, especially diagnosis and treatment, is worse.ObjectivesTo analyze the differences in the clinical characteristics of OP (demographics, comorbidities, diagnosis, and treatment) in an gold star Fracture Liaison Service (FLS).MethodsDesign: Observational, prospective, analytical study of usual clinical practice. All patients treated from an FLS from May 2018 to August 2021 were prospectively included. Of each patient, 160 clinical variables were introduced in a

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Harrowfield, Jack M., Raj Pal Sharma, Brian W. Skelton, and Allan H. White. "Structural Systematics of 2/4-Nitrophenoxide Complexes of Closed-Shell Metal Ions. III 2/4-Nitrophenoxides of Univalent Heavy Metals." Australian Journal of Chemistry 51, no. 8 (1998): 735. http://dx.doi.org/10.1071/c97100.

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Room-temperature single-crystal X-ray studies are recorded for 2- and 4-nitrophenoxide salts of silver(I) and thallium(I), M(2-np) and Tl(4-np) (anhydrous), and Ag(4-np).H2O. Ag(2-np) is monoclinic, P21/c, a 9·012(4), b 5·743(5), c 12·594(5) Å, β 104·34(4)°, Z = 4; conventional R on |F| was 0·042 for No 1378 independent ‘observed’ (I > 3σ(I)) reflections. Tl(2-np) is monoclinic, C2/c, a 27·250(3), b 3·712(1), c 15·147(3) Å, β 114·41(1)°, Z = 8, R 0·025 for No 1346. Ag(4-np).H2O is monoclinic, P21/a, a 5·613(6), b 13·191(7), c 9·844(5) Å, β 92·50(6)°, Z = 4, R 0 ·033 for No 622. Tl(4-np) is

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Semenova, Lioubov I., and Allan H. White. "Structural Systematics of Rare Earth Complexes. XIX (Hydrated) 1 : 2 Mononuclear Adducts of Lanthanoid(III) Chlorides with 2,2′-Bipyridine and 1,10-Phenanthroline." Australian Journal of Chemistry 52, no. 6 (1999): 571. http://dx.doi.org/10.1071/ch98052.

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Room-temperature single-crystal X-ray structure determinations are recorded for a number of adducts of hydrated lanthanoid(III) trichlorides with 2,2′-bipyridine (‘bpy’) and 1,10-phenanthroline (‘phen’), crystallized from water, methanol or ethanol solutions, containing mononuclear arrays with 1 : 2 Ln/bpy or phen stoichiometry. LaCl3/phen/H2O(1 : 3 : 9), [(phen)2La(OH2)5]Cl3.phen.4H2O, although of overall 1 : 3 LaCl3/phen stoichiometry, has a lattice phen; it is orthorhombic, Pnna, a 19·947(7), b 16·457(5), c 12·213(2) Å, Z = 4; conventional R on |F| was 0·030 for No 2567 ‘observed’ (I >3σ

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Essayli, Jamal H., Jessica M. Murakami, Rebecca E. Wilson, and Janet D. Latner. "The Impact of Weight Labels on Body Image, Internalized Weight Stigma, Affect, Perceived Health, and Intended Weight Loss Behaviors in Normal-Weight and Overweight College Women." American Journal of Health Promotion 31, no. 6 (2016): 484–90. http://dx.doi.org/10.1177/0890117116661982.

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Purpose: To explore the psychological impact of weight labels. Design: A double-blind experiment that randomly informed participants that they were “normal weight” or “overweight.” Setting: Public university in Honolulu, Hawai‘i. Participants: Normal-weight and overweight female undergraduates (N = 113). Measures: The Body Image States Scale, Stunkard Rating Scale, Weight Bias Internalization Scale, Positive and Negative Affect Schedule, General Health question from the 12-item Short Form Health Survey, modified version of the Weight Loss Methods Scale, and a manipulation check. Analysis: A 2

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Ma, Jianhong, Zhenxin Zhu, Xiao Chen, et al. "A cross-sectional survey of nutrition labelling use and its associated factors on parents of school students in Shanghai, China." Public Health Nutrition 21, no. 8 (2018): 1418–25. http://dx.doi.org/10.1017/s1368980018000332.

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AbstractObjectiveTo understand parents’ knowledge and use of nutrition labelling and to explore its associated factors.DesignCross-sectional survey.SettingTwo schools providing a nine-year educational programme in Putuo District, Shanghai, China, were selected for the study. Information was included on demographic data and knowledge of the Chinese Food Pagoda.SubjectsStudents and their parents (n 1770) participated in a questionnaire survey.ResultsOf questionnaires, 1766 were completed (response rate 99·8 %). Utilization rate of nutrition labelling was 19·3 %. Among 624 parents knowing nutriti

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Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics

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Gomes, Tiago Halyson de Oliveira, Welleson Feitosa Gazel, Emanuela Ferreira Goulart, Jennifer Lee Gonçalves, Gabriel Vargas Maia Chaves, and Lígia Luana Freire da Silva. "ÓBITOS DEVIDOS À SEPSE ESTREPTOCÓCICA NO BRASIL: ANÁLISE DE 13 ANOS." Revista ft 29, no. 143 (2025): 45–46. https://doi.org/10.69849/revistaft/ch10202502210945.

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Introdução: A sepse é uma síndrome caracterizada por uma resposta inflamatória exacerbada a uma infecção, levando à disfunção orgânica e risco elevado de morte. Fatores de risco como o uso de cateteres, sonda uretral, imunossupressão, comorbidades, infecções pré-existentes, resistência antimicrobiana e estado nutricional comprometido são determinantes importantes para o desenvolvimento da doença. Objetivos: O objetivo do presente trabalho é realizar o levantamento epidemiológico acerca dos óbitos por casos de septicemia estreptocócica no Brasil, em um período de 13 anos. Bem como realizar o le

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Steen, R. W. J. "A comparison of soya-bean meal, fish meal and maize gluten feed as protein sources for calves offered grass silage ad libitum." Animal Science 54, no. 3 (1992): 333–39. http://dx.doi.org/10.1017/s000335610002078x.

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AbstractTwo experiments were carried out to evaluate extracted soya-bean meal, fish meal and maize gluten feed as protein supplements for calves offered grass silage ad libitum. The five treatments used in experiment 1 consisted of 1·4 kg per head daily of concentrate dry matter (DM) consisting of (g/kg) 50 molasses and 25 minerals and vitamins plus (1) 925 barley (B), (2) 700 B and 225 extracted soya-bean meal (SBM), (3) 785 B and 140 fish meal (FM), (4) 925 maize gluten feed (MGF) and (5) 2·25 kg DM per head daily of concentrate (1). Those used in experiment 2 consisted of 1·4 kg per head da

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Kaye, S. B., J. Paul, J. Cassidy, et al. "Mature results of a randomized trial of two doses of cisplatin for the treatment of ovarian cancer. Scottish Gynecology Cancer Trials Group." Journal of Clinical Oncology 14, no. 7 (1996): 2113–19. http://dx.doi.org/10.1200/jco.1996.14.7.2113.

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PURPOSE In 1992, we reported the first results of a randomized study in ovarian cancer, comprising two doses of cisplatin and indicated a significant difference (P = .0008) in median survival. Four years later, we now describe the results of this trial. PATIENTS AND METHODS After a median follow-up of 4 years and 9 months, 115 of 159 cases of advanced ovarian cancer, originally randomized to receive six cycles of cyclophosphamide 750 mg/m2 and either a high dose (HD) of 100 mg/m2 cisplatin or a low dose (LD) of 50 mg/m2 (LD) cisplatin, have now died. RESULTS The overall survival for HD and LD

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Harrowfield, Jack M., Raj Pal Sharma, Brian W. Skelton, and Allan H. White. "Structural Systematics of 2/4-Nitrophenoxide Complexes of Closed-Shell Metal Ions. IV [Acid Salts] of the 4-Nitrophenoxides of Group 1." Australian Journal of Chemistry 51, no. 8 (1998): 747. http://dx.doi.org/10.1071/c97101.

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Room-temperature single-crystal X-ray studies are recorded for a number of ‘acid salts’ formed between Group 1 salts of 4-nitrophenol, M(4-np), and the parent ligand 4-npH, variously hydrated. The 1 : 1 salts M(4-np)(4-npH).x H2O are found for all of M = Li, Na, K, Rb and Cs. The lithium adduct (tetrahydrate) is monoclinic, C2/c, a 19·438(4), b 11·207(2), c 7·421(2) Å, β 91·38(2)°, Z = 4, conventional R on |F| being 0·043 for 1369 independent ‘observed’ (I > 3σ(I)) diffractometer reflections. The sodium adduct (dihydrate) is monoclinic, C2, a 2·174(3), b 3·674(2), c 10·358(1) Å, β 117·21(1)

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Nolan, Annette L., Christine C. Allen, Robert C. Burns, Donald C. Craig, and Geoffrey A. Lawrance. "Monomeric and Dimeric Cobalt(III) Polyoxomolybdates: Crystal Structures and Cyclic Voltammetry of Na3 [H6CoMo6O24].8H2O and K6 [H4Co2Mo10O38].7H2O." Australian Journal of Chemistry 51, no. 9 (1998): 825. http://dx.doi.org/10.1071/c97218.

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The crystal structures of Na3 [H6CoMo6O24].8H2O and K6 [H4Co2Mo10O38].7H2O have been determined by X-ray diffraction. The monomer, Na3 [H6CoMo6O24].8H2O, is triclinic, space group P-1, a 6·451(1), b 10·866(2), c 10·922(2) Å, α 109·20(1), β 106·90(1), γ 95·43(1)°, V 676·3(2) Å3, Z 1, and the structure was solved to an R1 value of 0·0243 (wR2 0·0784) for 3761 independent observed reflections. The anion exhibits the well known Anderson structure with six octahedral MoO6 edge-sharing units surrounding the central ‘CoO6’ octahedron, with all metals in a common plane. The dimer, K6 [H4Co2Mo10O38].7H

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Baraliakos, X., E. Pournara, D. D. Gladman, P. J. Mease, S. Jahandideh, and L. Coates. "POS1110 PATIENT CLUSTERS IDENTIFIED BY MACHINE LEARNING: DATA FROM A POOLED ANALYSIS OF PHASE-3 TRIALS OF SECUKINUMAB IN PSORIATIC ARTHRITIS, ANKYLOSING SPONDYLITIS AND PSORIATIC ARTHRITIS WITH AXIAL MANIFESTATIONS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 879.1–879. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2975.

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BackgroundUniversally acceptable criteria to define axial psoriatic arthritis (PsA) are lacking. Machine learning (ML) algorithms can detect patterns from large clinical datasets and identify clusters with potential therapeutic or prognostic significance in PsA patients (pts) with axial manifestations.[1]ObjectivesTo identify pt clusters based on baseline (BL) demographics and clinical indicators to support characterisation of the axial PsA phenotype within the spondyloarthritis (SpA) spectrum.MethodsPooled BL demographics and clinical data of secukinumab (SEC)-treated pts from 10 Phase-3 stud

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Albero, G., V. Longobardi, G. Zullo, et al. "144 INFLUENCE OF REPEATED OVUM PICKUP ON BUFFALO WELFARE." Reproduction, Fertility and Development 26, no. 1 (2014): 185. http://dx.doi.org/10.1071/rdv26n1ab144.

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The aim of this work was to evaluate the effect of repeated ovum pickup (OPU) on buffalo welfare. The OPU was carried out as previously described (Neglia et al. 2003 Theriogenology 59, 1123–1130) twice per week on 11 buffalo cows at 121 ± 15 days in milk for 2 months (end of October–end of December). Blood samples were collected before the beginning of the trial (time 0), after 1 month (time 1), and after 2 months (time 2) in animals that had undergone OPU and in control animals (n = 10) of the same herd. The following parameters of clinical immunology were evaluated on sera: haemolytic comple

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Lozano, Miguel, Ana Galan, Roberto Mazzara, Laurence Corash, and Gines Escolar. "Leucocyte-Reduced Buffy Coat Platelet Concentrates (BCPC) Treated with INTERCEPT™ Stored up to 7 Days: Hemostatic Function in a Whole Blood Flow System." Blood 106, no. 11 (2005): 956. http://dx.doi.org/10.1182/blood.v106.11.956.956.

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Abstract Background: The risk of bacterial growth has limited the shelf life of platelet concentrates (PC) to 5 days. Modern platelet storage containers facilitate storage for up to 7 days, if bacterial contamination is prevented. INTERCEPT (Baxter, La Chatre, France; Cerus, Concord, CA) photochemical treatment (PCT) for pathogen reduction based on amotosalen (150μM) and UVA illumination (3 J/cm2) inactivates high titers of bacteria in PC (Transfusion2004; 44: 1496–1504). Adhesion and aggregation of platelets to injured vascular surfaces are critical aspects of platelet hemostatic function. In

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Moghanaki, Drew, Renjian Jiang, David Gutman, et al. "Utilization patterns of immune checkpoint inhibitors (ICI) for non-small cell lung cancer (NSCLC) within the veterans health administration (VHA)." Journal of Clinical Oncology 38, no. 15_suppl (2020): e21630-e21630. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e21630.

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e21630 Background: ICI are used routinely for treatment of lung cancer. We investigated the utilization of PD-1/PD-L1 inhibitors for NSCLC in the VHA. Methods: The VHA Corporate Data Warehouse was queried for data on ICI utilization in NSCLC [IRB #00113521]. The first date of any ICI dispensed was January 6, 2015 and therefore this investigation evaluated all patients diagnosed with NSCLC between 2015 –2019. Results: A total of 27,586 Veterans were diagnosed with NSCLC during the study period with demographics: 76.3% Caucasian, 16.3% black; 97.0% male; median age 71 years. Stage distribution w

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Carcao, Manuel, Mariana Silva, Michele David, et al. "IVMP+IVIG raises platelet counts faster than IVIG alone: results of a randomized, blinded trial in childhood ITP." Blood Advances 4, no. 7 (2020): 1492–500. http://dx.doi.org/10.1182/bloodadvances.2019001343.

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Abstract Children with immune thrombocytopenia (ITP) rarely suffer from life-threatening bleeds (eg, intracranial hemorrhage). In such settings, the combination of IV methylprednisolone (IVMP) with IV immune globulin (IVIG) is used to rapidly increase platelet counts (PCs). However, there are no controlled data to support using combination therapy over IVIG alone. We conducted a randomized, double-blind, placebo-controlled study to evaluate the rapidity of the PC increment and associated adverse events (AEs) between 2 regimens: A (IV placebo) and B (IVMP 30 mg/kg), both given over 1 hour, foll

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Durig, James R., Chunhua Pan, Witold Witkowski, and Gamil A. Guirgis. "Conformational stability, infrared and Raman spectra, and vibrational assignment of ethyl bromogermane." Canadian Journal of Chemistry 82, no. 6 (2004): 964–77. http://dx.doi.org/10.1139/v04-048.

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The infrared spectra (320030 cm1) of ethyl bromogermane, CH3CH2GeH2Br, in the gaseous phase and of amorphous and annealed solid samples as well as the Raman spectrum (3200100 cm1) of the liquid have been recorded. Variable-temperature (105 to 150 °C) studies of the infrared spectra of a sample dissolved in liquid krypton have been carried out. From these data, the enthalpy difference between the gauche and trans conformers has been determined to be 158 ± 16 cm1 (1.89 ± 0.20 kJ/mol), with the gauche conformer being the more stable form. This result is consistent with the prediction from

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Puteri, Ni Made Martini, Hamdi Muluk, Amarina Ariyanto, and Bagus Takwin. "THE MEANING OF GRATIFICATION, MORAL CREDENTIAL, AND THE VALUE OF SELFLESSNESS ACTION IN VIOLATIONS COMMITTED BY A RESPECTED PERSON." Jurnal Psikologi 19, no. 4 (2020): 373–87. http://dx.doi.org/10.14710/jp.19.4.373-387.

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This study aims to prove how kindness conducted by the group, the definition of violations and the value of doing good, can affect moral credential in the form of the leniency of punishment for corruptors. Sample 319 polices and doctors divided into two segments. This study uses a population-based survey experiment method. Participants divided into moral credential with the narrative noble duty, and non-moral credential with neutral narratives. Researchers require each participant to provide criminal punishment and social reactions to the vignette of violation cases due to receiving gratificat

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Rudenko, M. L., N. O. Ioffe, V. V. Vayda, and A. A. Pavlykova-Chertovska. "Experience in the Use of Artificial Fibrillation in the Correction of Postinfarction Left Ventricular Aneurysms as the Most Appropriate Alternative to Pharmaco-Cold Protection of the Heart." Ukrainian journal of cardiovascular surgery, no. 1 (42) (March 16, 2021): 44–46. http://dx.doi.org/10.30702/ujcvs/21.4203/r008044-046/007.64.

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Coronary heart disease (CHD) is the leading cause of death in the world. In most cases, the disease is complicated by myocardial infarction (MI) followed by the formation of a left ventricular aneurysm (LVA), ruptures of the interventricular septum, ischemic cardiomyopathy, mitral regurgitation and arrhythmias. Postinfarction left ventricu-lar aneurysm is the most common and severe complication of CHD. There are a lot of methods of LVA surgical correc-tion, including Cooley’s linear repair technique, purse-string technique of Jatene and endoventriculoplasty using the Dor technique. Over the la

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Fairushina, I., D. Abdulganieva, E. Kirillova, and E. Mukhametshina. "AB1091 FREQUENCY OF ULTRASOUND ENTHESITIS AND SYNOVITIS IN DIFFERENT ANATOMICAL SITES OF UPPER AND LOWER EXTREMITIES IN PATIENTS WITH PSORIATIC ARTHRITIS: CROSS-SECTIONAL STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1834.2–1835. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5900.

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Background:Psoriatic arthritis (PsA) is characterized by asymptomatic enthesitis and synovitis1. The location of pathological lesions is not clear. Furthermore, ultrasound (US) enthesitis indices assess limited number of entheses.Objectives:To detect the most frequent sites of US enthesitis and synovitis in PsA.Methods:57 PsA patients were enrolled to the study. US examination included bilateral large 14 joints; entheses of tendons and ligaments in the projection of examined joints (total number - 54). Totally, 798 joints, 3078 entheses were examined. The study was conducted by US rheumatologi

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Pisuitthanakan, MD, Satapong. "Comparison of the Posterior and Paraspinal Approaches for the Treatment of Thoracolumbar Burst Fractures: A Randomized Controlled Trial." Journal of Southeast Asian Orthopaedics 46, no. 1 (2022): 17–23. http://dx.doi.org/10.56929/jseaortho.v46i1.12.

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Purpose: Burst fractures cause over half of all thoracolumbar fractures, for which the posterior approach has been considered the standard approach. The paraspinal approach has proven safe and effective for thoracolumbar injury. This study aimed to compare the clinical and radiographic outcomes between the two approaches. Methods: This randomized controlled trial included 24 patients with isolated thoracolumbar burst fractures between July 2016 and August 2018. Patients were categorized into two groups: paraspinal and posterior approaches. The primary outcome was postoperative pain on days 1,

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Penson, Richard T., Ricardo Villalobos Valencia, David Cibula, et al. "Olaparib Versus Nonplatinum Chemotherapy in Patients With Platinum-Sensitive Relapsed Ovarian Cancer and a Germline BRCA1/2 Mutation (SOLO3): A Randomized Phase III Trial." Journal of Clinical Oncology 38, no. 11 (2020): 1164–74. http://dx.doi.org/10.1200/jco.19.02745.

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PURPOSE A phase II study (ClinicalTrials.gov identifier: NCT00628251 ) showed activity of olaparib capsules versus pegylated liposomal doxorubicin in patients with germline BRCA-mutated platinum-resistant or partially platinum-sensitive relapsed ovarian cancer. We conducted a phase III trial (SOLO3) of olaparib tablets versus nonplatinum chemotherapy in patients with germline BRCA-mutated platinum-sensitive relapsed ovarian cancer who had received at least 2 prior lines of platinum-based chemotherapy. PATIENTS AND METHODS In this randomized, open-label trial, patients were randomly assigned 2:

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Veena, Kattiyeri Puthenveedu, Elezebeth Mathews, Prakash Babu Kodali, and Kavumpurathu Raman Thankappan. "Trends and correlates of hardcore smoking in India: findings from the Global Adult Tobacco Surveys 1 & 2." Wellcome Open Research 6 (December 20, 2021): 353. http://dx.doi.org/10.12688/wellcomeopenres.17465.1.

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Background: Data on prevalence of hardcore smoking (HCS) among different socioeconomic status (SES) groups in low- and middle-income countries are limited. We looked at the prevalence and pattern of HCS in India with the following objectives: 1) to analyse the association between SES and HCS, 2) to find trends in HCS in different SES groups and 3) to find state-wide variations in hardcore smoking. Methods: Data of individuals aged ≥25 years from the Global Adult Tobacco Survey (GATS) India 2009-10 (N= 9223) and 2016-17 (N= 7647) were used for this study. If an individual met all the following

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Veena, Kattiyeri Puthenveedu, Elezebeth Mathews, Prakash Babu Kodali, and Kavumpurathu Raman Thankappan. "Trends and correlates of hardcore smoking in India: findings from the Global Adult Tobacco Surveys 1 & 2." Wellcome Open Research 6 (February 17, 2022): 353. http://dx.doi.org/10.12688/wellcomeopenres.17465.2.

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Background: Data on prevalence of hardcore smoking (HCS) among different socioeconomic status (SES) groups in low- and middle-income countries are limited. We looked at the prevalence and pattern of HCS in India with the following objectives: 1) to analyse the association between SES and HCS, 2) to find trends in HCS in different SES groups and 3) to find state-wide variations in hardcore smoking. Methods: Data of individuals aged ≥25 years from the Global Adult Tobacco Survey (GATS) India 2009-10 (N= 9223) and 2016-17 (N= 7647) were used for this study. If an individual met all the following

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Choueiri, Toni K., Todd Michael Bauer, Jaime R. Merchan, et al. "Updated results from the phase 2 LITESPARK-003 study of belzutifan plus cabozantinib in patients with advanced clear cell renal cell carcinoma (ccRCC)." Journal of Clinical Oncology 43, no. 5_suppl (2025): 549. https://doi.org/10.1200/jco.2025.43.5_suppl.549.

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549 Background: In the phase 2 LITESPARK-003 study (NCT03634540), belzutifan plus cabozantinib showed antitumor activity in patients with advanced ccRCC who were treatment-naive (cohort 1) or previously treated (cohort 2). We present updated results from cohorts 1 and 2 with a median follow-up of 34.4 months and 49.9 months, respectively. Methods: Eligible patients had advanced or metastatic ccRCC and ECOG performance status of 0 or 1. Cohort 1 included patients with no prior systemic therapy. Cohort 2 included patients who had received prior immunotherapy and ≤2 systemic regimens. Starting do

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Canonaco, Francesco, Anna Tobler, Gang Chen, et al. "A new method for long-term source apportionment with time-dependent factor profiles and uncertainty assessment using SoFi Pro: application to 1 year of organic aerosol data." Atmospheric Measurement Techniques 14, no. 2 (2021): 923–43. http://dx.doi.org/10.5194/amt-14-923-2021.

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Abstract. A new methodology for performing long-term source apportionment (SA) using positive matrix factorization (PMF) is presented. The method is implemented within the SoFi Pro software package and uses the multilinear engine (ME-2) as a PMF solver. The technique is applied to a 1-year aerosol chemical speciation monitor (ACSM) dataset from downtown Zurich, Switzerland. The measured organic aerosol mass spectra were analyzed by PMF using a small (14 d) and rolling PMF window to account for the temporal evolution of the sources. The rotational ambiguity is explored and the uncertainties of

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McRae, Hannah L., Markus Horchler, Nadine Schwarz, et al. "Higher D-Dimer and Prothrombin Fragment 1+2 in Patients Taking Direct Oral Anticoagulants As Compared to Vitamin K Antagonists." Blood 144, Supplement 1 (2024): 1251. https://doi.org/10.1182/blood-2024-210238.

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Introduction: A central question regarding anticoagulant treatment of venous thromboembolism (VTE) is how long maintenance therapy should be continued. Current decision algorithms, which were developed during the era of vitamin K antagonists (VKA), are based on D-dimer measurements before and/or after discontinuation of anticoagulants. However, recent clinical data from the Apidulcis study questioned the validity of this approach in patients taking direct oral anticoagulants (DOACs). One reason for this may be generally higher D-dimer levels in patients on DOACs than in those on VKAs, for whic

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Sasaki, Koji, Ildefonso Ismael Rodriguez-Rivera, Hagop M. Kantarjian, et al. "Correlation of Lymphocyte Count with Treatment Response to Tyrosine Kinase Inhibitors in Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase." Blood 124, no. 21 (2014): 4538. http://dx.doi.org/10.1182/blood.v124.21.4538.4538.

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Abstract Background: Total lymphocyte count (TLC) has been shown to correlate with outcomes in patients (pts) with acute leukemia. The clinical correlation to TLC in pts with chronic myeloid leukemia in chronic phase (CML-CP) who were treated with a tyrosine-kinase inhibitor (TKI) is unclear. Methods: Lymphocyte data in pts with newly diagnosed CML-CP who were enrolled in consecutive or parallel clinical trials with front-line imatinib (IM), nilotinib (Nilo), or dasatinib (Dasa) were collected at the time of diagnosis, and 3 and 6 months (M) after the start of TKI. Relative lymphocytrosis (RLC

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Bianchi, Paola, Elisa Fermo, Fulvio Mozzi, Maurizio Marconi, and Alberto Zanella. "Presence of JAK2 V617F Mutation in Peripheral Blood of Blood Donors with Upper-Limit Hematocrit and Platelet Values." Blood 110, no. 11 (2007): 2533. http://dx.doi.org/10.1182/blood.v110.11.2533.2533.

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Abstract The somatic mutation V617F of JAK2 gene has been identified as a pathogenic factor in typical chronic myeloproliferative diseases (MPDs), in particular polycythemia vera, essential thrombocythemia, and myelofibrosis with myeloid metaplasia. Recently, two studies showed the presence of this mutation also in 37/3935 subjects with non haematological diseases (Xu et al, 2006) and 5/52 healthy donors (Sidon et al, 2006), suggesting that V617F mutation may occur in the absence of MPD phenotype and that probably is not sufficient per se to induce MPDs. The aim of this study was to search for

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Bowmaker, Graham A., Jack M. Harrowfield, Peter C. Junk, Brian W. Skelton, and Allan H. White. "Syntheses, Structures and Vibrational Spectra of Some Dimethyl Sulfoxide Solvates of Bismuth(III) Bromide and Iodide." Australian Journal of Chemistry 51, no. 4 (1998): 285. http://dx.doi.org/10.1071/c97035.

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Room-temperature single-crystal X-ray studies are recorded for some dimethyl sulfoxide (dmso) solvates of bismuth(III) bromide and iodide. Colourless BiBr3.3dmso is triclinic, P-1, a 8·467(4), b 9·109(4), c 13·901(4) Å, α 76·34(4), β 76·95(4), γ 64·56(4)°, Z = 2; conventional R on |F| was 0·050 for No 2306 independent ‘observed’ (I > 3σ(I)) reflections. The complex is mononuclear with a quasi-octahedral fac-bismuth environment, [(dmso-O)3BiBr3], isomorphous with the previously determined chloride. Orange BiI3-2dmso is triclinic, P-1, a 12·558(2), b 8·962(2), c 8·342(1) Å, α 61·85(1), β 78·2

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Park, John K., Tiffany Hodges, Leopold Arko, et al. "Scale to Predict Survival After Surgery for Recurrent Glioblastoma Multiforme." Journal of Clinical Oncology 28, no. 24 (2010): 3838–43. http://dx.doi.org/10.1200/jco.2010.30.0582.

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Purpose Despite initial treatment with surgical resection, radiotherapy, and chemotherapy, glioblastoma multiforme (GBM) virtually always recurs. Surgery is sometimes recommended to treat recurrence. In this study, we sought to devise a preoperative scale that predicts survival after surgery for recurrent glioblastoma multiforme. Patients and Methods The preoperative clinical and radiographic data of 34 patients who underwent re-operation of recurrent GBM tumors were analyzed using Kaplan-Meier survival analysis and Cox proportional hazards regression modeling. The factors associated with decr

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Long, Kelvin. "Application of the HeliosX ICF Advanced Propulsion Mission Analysis Code to Perturbed Interstellar Design Models." Journal of the British Interplanetary Society 76, no. 3 (2023): 94–111. http://dx.doi.org/10.59332/jbis-076-03-0094.

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HeliosX is a system integrated programming design tool which has the purpose of calculating spacecraft mission profile and propulsion performance for inertial confinement fusion (ICF) driven designs. This code uses the vehicle configuration input and capsule assumptions and then calculates the likely mission profile for a given destination target. The key technology is the inclusion of the fusion propulsion system and an adequate modelling of its likely energy outputs. This paper discusses calculations for perturbed design concepts from a baseline model in both series and parallel thrust mode.

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Planchon, F., A. J. Cavagna, D. Cardinal, L. André, and F. Dehairs. "Late summer particulate organic carbon export and twilight zone remineralisation in the Atlantic sector of the Southern Ocean." Biogeosciences 10, no. 2 (2013): 803–20. http://dx.doi.org/10.5194/bg-10-803-2013.

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Abstract. As part of the GEOTRACES Bonus-GoodHope (BGH) expedition (January–March 2008) in the Atlantic sector of the Southern Ocean, particulate organic carbon (POC) export was examined from the surface to the mesopelagic twilight zone using water column distributions of total 234Th and biogenic particulate Ba (Baxs). Surface POC export production was estimated from steady state and non steady state modelling of 234Th fluxes, which were converted into POC fluxes, using the POC/234Th ratio of large, potentially sinking particles (> 53 μm) collected via in situ pumps. Deficits in 234Th activ

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Planchon, F., A. J. Cavagna, D. Cardinal, L. André, and F. Dehairs. "Late summer particulate organic carbon export and twilight zone remineralisation in the Atlantic sector of the Southern Ocean." Biogeosciences Discussions 9, no. 3 (2012): 3423–77. http://dx.doi.org/10.5194/bgd-9-3423-2012.

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Abstract. During the Bonus-GoodHope (BGH) expedition (Jan–Mar 2008) we studied the water column distribution of total 234Th and biogenic particulate Ba (Baxs) in the Atlantic sector of the Southern Ocean. The objective was to assess the export flux of particulate organic carbon (POC) from the surface to the mesopelagic twilight zone along a section between the Cape Basin and Weddell Gyre. Export production of POC was estimated from steady state and non steady state export fluxes of 234Th which were converted into POC fluxes, using the POC/234Th ratio of large (>53 μm) suspended particles, c

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Hodenius, Michael A. J., Thoralf Niendorf, Gabriele A. Krombach, et al. "Synthesis, Physicochemical Characterization and MR Relaxometry of Aqueous Ferrofluids." Journal of Nanoscience and Nanotechnology 8, no. 5 (2008): 2399–409. http://dx.doi.org/10.1166/jnn.2008.18276.

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The synthesis and characterization of ferrofluid based MR contrast agents, which offer R2* versatility beyond that of ferucarbotran, is described. Ferrofluids were formed after stabilizing magnetite cores with dodecanoic acid (a), oleic acid (b), dodecylamine (c), citric acid (d) or tartaric acid (e). Core sizes were deduced from TEM micrographs. Magnetic properties were determined by SQUID magnetometry. Hydrodynamic particle diameters were determined by dynamic light scattering measurements. Zeta potentials were measured by combining laser Doppler velocimetry and phase analysis light scatteri

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Michallet, Mauricette, Quoc Hung Le, Marie Robin, et al. "Double Cord Blood Cell (CBC) Hematopoietic Stem Cell Transplantation after Standard or Reduced Intensity Conditioning: Report of the SFGMTC Registry." Blood 112, no. 11 (2008): 1972. http://dx.doi.org/10.1182/blood.v112.11.1972.1972.

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Abstract This analysis concerned 164 allogeneic HSCT after standard (Std) or reduced intensity conditioning (RIC) using double cord blood cells (CBC), reported to the SFGM-TC registry. There were 57 females (F) and 107 males (M) with a median age of 39.5 years (18–66). The diagnosis pretransplant were acute leukaemia: 93 (56 AML and 37 ALL), MDS: 9, MPS: 9 (CML: 4), CLL: 5, NHL: 18, HD: 7, MM: 13, AA: 7, other diseases: 3 (2 inborn errors and 1 solid tumour). The median interval between diagnosis and HSCT was 20.6 months (2.6–385.5). Among 154 evaluated patients (pts), disease status prior con

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Lee, ChoongGon, and Samuel Koomson. "Overpotential Behavior of Electrolysis and Fuel Cell Modes of Molten Carbonate Cells." ECS Meeting Abstracts MA2023-02, no. 48 (2023): 2448. http://dx.doi.org/10.1149/ma2023-02482448mtgabs.

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Molten carbonate is an high operating temperature electrolyte for the fuel cell (MCFC) and electrolysis cells (MCEC). In particular, the liquid molten carbonates allow the reversible operation between fuel cell and electrolysis cells. The electrode kinetics and mass transfer characteristics of MCFC have been rather extensively investigated compared with those of MCEC. In this work, the mass transfer behaviors between MCFC and MCEC have been focused by experimental way with 100 cm2 class bench cells. The electrodes and matrix in the cell were supplied by KIST in Korea. The cells were operated a

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Sorokina, L., I. Avrusin, R. Raupov, et al. "POS1299 RISK FACTORS OF TOTAL HIP ARTHROPLASTY IN JUVENILE ARTHRITIS WITH HIP INVOLVEMENT." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 931–32. http://dx.doi.org/10.1136/annrheumdis-2021-eular.857.

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Background:Hip osteoarthritis (HOA) is a severe outcome of juvenile idiopathic arthritis (JIA) itself and also can be result of corticosteroid (CS) treatment, if it was used. Total hip arthroplasty (THA) is the last step in JIA treatment and indicates ineffectiveness of conservative treatment.Objectives:We aimed to evaluate risk factors which lead to THA in JIA patients with HOA.Methods:753 patients aged 2-17 years were included in our retrospective study during the last 10 years. Diagnosis was made according to ILAR criteria. Clinical, laboratory and radial examinations were evaluated. Diagno

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Solomon, Suniti, N. Kumarasamy, A. K. Ganesh, and R. Edwin Amalraj. "Prevalence and risk factors of HIV-1 and HIV-2 infection in urban and rural areas in Tamil Nadu, India." International Journal of STD & AIDS 9, no. 2 (1998): 98–103. http://dx.doi.org/10.1258/0956462981921756.

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Summary: We aim to study the factors associated with the prevalence of HIV-1 and HIV-2 infection in the urban and rural areas of Tamil Nadu, India. The population of Tamil Nadu is approximately 60 million. Between April 94 and March 95, 992 samples from 5 representative urban centres and 1071 samples from 5 representative rural centres were collected and studied. A questionnaire was administered privately and it preceded collection of each sample. Samples were screened using ELISA and antibodies to HIV-1 and HIV-2 were confirmed using Western blot. The study was anonymous and unlinked. The pre

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Ortiz-Cervantes, Elías, José Miguel Hernández-Cruz, and Georgel Moctezuma-López. "Efecto de densidades de población sobre crecimiento y rendimiento de hule en Veracruz." Revista Mexicana de Ciencias Agrícolas 13, no. 7 (2022): 1221–31. http://dx.doi.org/10.29312/remexca.v13i7.2652.

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En México, el rendimiento promedio anual de hule (Hevea brasiliensis [Willd. ex A. Juss] Muell. Arg.) es inferior a 1.2 t ha-1, mediante la optimización de la densidad de población se busca aumentar el rendimiento y productividad. El trabajo se realizó en la región central del estado de Veracruz. Se evaluaron los arreglos de plantación 4x2, 6x3 (testigo), 8x4 y 10x5 m, con densidades de 1 250, 556, 312 y 200 árboles ha-1, respectivamente. El diseño experimental fue bloques al azar con cuatro repeticiones y 40 árboles del clon IAN-754 por unidad experimental. Las principales variables evaluadas

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Guler, Sevil, Gulcan Eyuboglu, Zehra Gocmen Baykara, et al. "The Effect of Stoma Site Marking on Stomal Complications: A Long-term Retrospective Study." Advances in Skin & Wound Care 37, no. 5 (2024): 254–59. http://dx.doi.org/10.1097/asw.0000000000000134.

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ABSTRACT OBJECTIVE To identify the effect of stoma site marking on stoma-related complications. METHODS The study sample included 639 individuals with stomas who were followed up in a stomatherapy unit in Turkey between January 1, 2017, and June 20, 2021. Researchers collected patient data from nursing records. Data were evaluated using number, percentage, χ 2, and logistic regression tests. RESULTS Of the individuals with stomas, 60.6% (n = 387) were men, and 72.6% (n = 464) had a cancer diagnosis. Their mean age was 60.16 (SD, 14.81) years. The stoma site was marked preoperatively in of 67.1

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Manoonkitiwongsa, Panya S., Cathy Jackson-Friedman, Paul J. McMillan, Robert L. Schultz, and Patrick D. Lyden. "INTRA-ARTERIAL INFUSION OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN NORMAL AND ISCHEMIC BRAINS HAS NO EFFECT ON ANGIOGENESIS." Stroke 32, suppl_1 (2001): 356. http://dx.doi.org/10.1161/str.32.suppl_1.356-b.

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P95 INTRODUCTION: Stimulation of angiogenesis in ischemic brains may be of major value in stroke therapy. Administration of vascular endothelial growth factor (VEGF) is considered particularly effective as an angiogenic factor for hypoxia-related injuries. We therefore quantitatively compared the effect of VEGF on microvessels of normal and ischemic brain cortices. Vascular parameters of microvessels measured included changes in numerical (N A ), volume (V v ), surface (S v ) and length (L v ) densities along with diameter. METHODS: VEGF 165 protein at 1μg/ml was infused into the common caroti

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Radchicov, V., V. Tzai, A. Kot, et al. "Efficiency of energy feed supplement Cobiotic Energy in diets for cows." Tehnologìâ virobnictva ì pererobki produktìv tvarinnictva, no. 2(150) (December 17, 2019): 81–92. http://dx.doi.org/10.33245/2310-9289-2019-150-2-81-92.

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The influence of feeding high-performance cows of the energy feed additive Cobiotic Energy on the physiological state and productivity have been studied. Experiments have been carried out on with groups of dairy cows with 10 animals each during 55 days. The diet of cows of the first control group consisted of haylage of cereal and leguminous plants, corn silage, molasses, cereal hay, and feed of own production. 0.3 kg of feed additive has been introduced into the diet of animals of the experimental group II 15 days before calving, in the first 10 days after calving, as compensation for energy

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Tsin, Andre, Chih Chen, Alexandre Ruggieri Serante, et al. "2090 Prospective Randomized Phase 2 Trial of Hypofractionated Stereotactic Radiation Therapy of 25 Gy in 5 Fractions Compared With 35 Gy in 5 Fractions in the Reirradiation of Recurrent Glioblastoma." Neurosurgery 71, Supplement_1 (2025): 270. https://doi.org/10.1227/neu.0000000000003360_2090.

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INTRODUCTION: Recurrent glioblastomas can potentially be treated with hypofractionated stereotactic radiation therapy (HSRT). METHODS: A prospective randomized phase 2 trial involved patients with recurrent glioblastoma (per the 2007 and 2016 WHO classification). A minimum interval from the first radiation therapy of 5 months and a gross tumor volume of 150 cc were required. Patients were randomized 1:1 to receive HSRT alone in 25 Gy/5 fx or 35 Gy/5 fx. The primary endpoint was progression-free survival (PFS) with a 2-sided ? of 0.15. RESULTS: From 2011 to 2019, 40 patients received HSRT, with

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Dowling, Michael M., Charles T. Quinn, Patricia Plumb, et al. "Acute silent cerebral ischemia and infarction during acute anemia in children with and without sickle cell disease." Blood 120, no. 19 (2012): 3891–97. http://dx.doi.org/10.1182/blood-2012-01-406314.

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Abstract We hypothesized that the silent cerebral infarcts (SCI), which affect up to 40% of children with sickle cell disease (SCD), could occur in the setting of acute anemic events. In a prospective observational study of children with and without SCD hospitalized for an illness associated with acute anemia, we identified acute silent cerebral ischemic events (ASCIE) in 4 (18.2%) of 22 with SCD and in 2 (6.7%) of 30 without SCD, using diffusion-weighted magnetic resonance imaging. Children with ASCIE had lower hemoglobin concentration than those without (median 3.1 vs 4.4 g/dL, P = .003). Th

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Eby, D., and J. Woods. "LO38: Hypoglycemia is a rare peri-seizure finding in pre-hospital patients." CJEM 19, S1 (2017): S40—S41. http://dx.doi.org/10.1017/cem.2017.100.

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Introduction: Conventional wisdom states that hypoglycemia is a frequent peri-seizure phenomenon and must be tested for. Conventional wisdom also lists hypoglycemia as a cause of seizures. Recent literature disputes this. Paramedic medical directives continue to direct paramedics to determine the blood sugar level on all seizure patients. The purpose of this study was to determine the frequency of hypoglycemia in patients identified as having “seizure” as the primary or final problem code in Ambulance Call Reports (ACRs) from a large regional paramedic base hospital program. Methods: We conduc

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Roy, Denis-Claude, Sandra Cohen, Lambert Busque, et al. "Phase I Clinical Study of Donor Lymphocyte Infusion Depleted of Alloreactive T Cells after Haplotype Mismatched Myeloablative Stem Cell Transplantation To Limit Infections and Malignant Relapse without Causing GVHD." Blood 108, no. 11 (2006): 309. http://dx.doi.org/10.1182/blood.v108.11.309.309.

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Abstract Patients with very high risk hematologic malignancies who cannot find an HLA-matched related or unrelated donor can benefit from haplo-mismatched transplantation. The latter is, however, complicated by frequent and severe infectious complications and disease relapse due to delayed immune reconstitution. We have previously reported that photodynamic therapy (PDT) could selectively deplete donor alloreactive populations while preserving lymphocytes for immune responses. Indeed, the dibromorhodamine derivative TH9402 (Celmed BioSciences) has a propensity to accumulate in activated but no

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Motoyama, Takeshi, Hiroaki Kawano, Kiyotaka Kugiyama, et al. "Endothelium-dependent vasodilation in the brachial artery is impaired in smokers: effect of vitamin C." American Journal of Physiology-Heart and Circulatory Physiology 273, no. 4 (1997): H1644—H1650. http://dx.doi.org/10.1152/ajpheart.1997.273.4.h1644.

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Cigarette smoking has been shown to cause endothelial dysfunction. To examine the effects of vitamin C and cigarette smoking on endothelium-dependent vasodilation, we measured the lumen diameter and flow velocity of the brachial arteries at rest, during reactive hyperemia following transient arterial occlusion, and after sublingual nitroglycerin (0.3 mg) in smokers ( n = 20) and nonsmokers ( n = 20) with high-resolution ultrasound after infusion of saline or saline plus vitamin C (10 mg/min for 20 min). We also performed the same study in smokers ( n = 15) before and 10 min after cigarette smo

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Rugo, Hope S., Alison T. Stopeck, Anil A. Joy, et al. "Randomized, Placebo-Controlled, Double-Blind, Phase II Study of Axitinib Plus Docetaxel Versus Docetaxel Plus Placebo in Patients With Metastatic Breast Cancer." Journal of Clinical Oncology 29, no. 18 (2011): 2459–65. http://dx.doi.org/10.1200/jco.2010.31.2975.

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Purpose This multicenter, randomized, double-blind, phase II study assessed safety and efficacy of axitinib plus docetaxel in metastatic breast cancer (MBC). Patients and Methods Women with MBC were randomly assigned 2:1 to receive docetaxel 80 mg/m2 once every 3 weeks plus axitinib 5 mg twice per day (combination arm) or placebo (placebo arm), following a lead-in phase I trial. The primary end point was time to progression (TTP). Results In all, 168 patients were enrolled; 112 were randomly assigned to axitinib and 56 to placebo. Median TTP was numerically longer in the combination arm than i

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