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Journal articles on the topic '159.955 (043.2)'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Bowmaker, Graham A., Frances M. M. Hannaway, Peter C. Junk, Aaron M. Lee, Brian W. Skelton, and Allan H. White. "Synthetic, Structural and Vibrational Spectroscopic Studies in Bismuth(III) Halide/N,N′-Aromatic Bidentate Base Systems. IV Bismuth(III) Halide/N,N′-Bidentate Ligand (1 : 1) Systems." Australian Journal of Chemistry 51, no. 4 (1998): 325. http://dx.doi.org/10.1071/c97039.

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Room-temperature single-crystal X-ray studies are recorded for a number of adducts of BiX3 and N,N′-bidentate ligand (2,2′-bipyridine (bpy) or 1,10-phenanthroline (phen)), devoid of coordinated solvent. BiBr3/bpy/MeCN (1 : 1 : 1) is triclinic P-1, a 12·129(2), b 9·955(4), c 7·748(1) Å, α 73·14(2), β 77·34(1), γ 69·79(2)°, Z = 2; conventional R on |F| was 0·036 for No 2252 independent ‘observed’ (I > 3σ(I)) reflections. The phen analogue is isomorphous, a 11·586(3), b 10·839(6), c 7·769(10) Å, α 73·70(7), β 76·67(7), γ 70·34(4)°, Z = 2, R 0·042 for No 800. BiI3/bpy (1 : 1) is triclinic, P-1,

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Alten, R., X. Mariette, R. M. Flipo, et al. "AB0207 ANALYSIS OF ABATACEPT TREATMENT RETENTION AND EFFICACY ACCORDING TO DISEASE DURATION AND TREATMENT LINE IN A REAL-WORLD SETTING." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1128.2–1130. http://dx.doi.org/10.1136/annrheumdis-2021-eular.955.

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Background:Longer disease duration and greater number of prior DMARDs have been associated with lower treatment efficacy in patients with RA.1 Abatacept is a biologic (b)DMARD for treatment of moderate-to-severe RA and is available in SC formulation, which may offer convenience benefits with efficacy similar to IV administration.2 ASCORE (Abatacept SubCutaneOus in Routine Clinical PracticE; NCT02090556) was a 2-year, observational, prospective, multicentre study of SC abatacept for treatment of RA in routine clinical practice.3Objectives:This post hoc analysis was conducted to determine if ret

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Brynda, Jiří, Bohumil Kratochvíl, and Ivana Císařová. "The determination of crystal structure of chromium(II) phosphite dihydrate, CrHPO3 2 H2O." Collection of Czechoslovak Chemical Communications 52, no. 7 (1987): 1742–47. http://dx.doi.org/10.1135/cccc19871742.

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The crystal structure of CrHPO3.2 H2O has been solved by the heavy atom method. The compound crystallizes in the orthorhombic space group P212121 with the unit cell parameters a = 679·25(8), b = 915·61(8), c = 752·2(1) pm, Z = 4. The structure was refined to the final reliability factor R = 0·043 for 1 040 observed reflexions (I > 1·96σ(I)). The structure consists of chains formed by CrO6 octahedra connected each other in vertices. The chains are interconnected by phosphite tetrahedra HPO3. Hydrogen bridges of water-phosphite tetrahedron and water-water types form space cross-linking of the

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BHANUSHALI, APARNA A., AASHISH CONTRACTOR, and BIBHU R. DAS. "Variant at 9p21 rs1333049 is associated with age of onset of coronary artery disease in a Western Indian population: a case control association study." Genetics Research 95, no. 5 (2013): 138–45. http://dx.doi.org/10.1017/s0016672313000189.

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SummaryThe 9p21 chromosomal region has been associated with coronary artery disease (CAD) in many genome wide association studies (GWAS). To date no information exists regarding the rs1333039 SNP which showed the strongest association in the WTCCC GWAS with CAD risk in the Indian population. The present study attempts to replicate the findings in the Indian population.Genotyping for rs1333049 was done in 229 cases and 151 controls by allele-specific real-time assay.A higher frequency of the risk allele rs1333049C was seen in cases (0·60) as compared with controls (0·49), which associated with

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Choe, Hannah, Amandeep Salhotra, Nosha Farhadfar, et al. "Dynamics of Overall and Organ-Specific Responses to Axatilimab in Chronic Graft-Versus-Host Disease: Analysis from the Agave-201 Study." Blood 144, Supplement 1 (2024): 98. https://doi.org/10.1182/blood-2024-209965.

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Introduction: Chronic graft-versus-host disease (cGVHD) is characterized by inflammatory and fibrotic pathology affecting multiple organs and leading to significant impairment. Axatilimab (AXA), an anti-colony-stimulating factor 1 receptor monoclonal antibody, targets monocytes and macrophages that are critical for inflammation and fibrosis in cGVHD. In the pivotal, phase 2 AGAVE-201 study (NCT04710576), AXA had robust clinical activity and was generally well tolerated in patients with cGVHD, with adverse events that were mostly low grade, reversible, and dose dependent (Wolff D, et al. Blood.

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Nieto, R., R. Quintana, E. Borba, et al. "POS1519 BASELINE CHARACTERISTICS OF A LONGITUDINAL, MULTINATIONAL, MULTIETHNIC STUDY OF LUPUS PATIENTS, WITH OR WITHOUT LUPUS NEPHRITIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1118.1–1120. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2738.

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BackgroundClinically evident kidney disease eventually occurs in up to one-half of SLE patients.ObjectivesTo describe sociodemographic, clinical, serological and treatment characteristics of a multicenter and multiethnic Latin American SLE cohort of patients with or without lupus nephritis (LN)MethodsGLADEL2.0 is an ongoing observational cohort. Patients were categorized according to renal involvement: Group I (LN never); II (prevalent renal involvement currently inactive); III (prevalent renal involvement, currently active) and IV (incident renal involvement). Demographic, clinical manifestat

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Lertwannawit, Aurathai, and Nak Gulid. "A Structural Relationship Between Domestic Tourist Satisfaction, Trust, Switching Barriers And Retention." International Business & Economics Research Journal (IBER) 13, no. 6 (2014): 1375. http://dx.doi.org/10.19030/iber.v13i6.8927.

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The objective of this study is to examine the direct effects of satisfaction, trust, and switching barriers on customer retention in Bangkok and Pattaya, Chonburi province. Four hundred and forty questionnaires were distributed as the means of data collection and analyzed using structural equation modeling (SEM). The results of testing hypotheses are as follows: The developed structural equation model of customer retention in Bangkok was congruent with empirical data as the criterion, as follows: (?2 = 141.098, df = 69, ?2/df = 2.045, GFI = .956, AGFI = .933, RMSEA = .049, RMR = .073, CFI = .9

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Exner, Ginka, Aleksandar Grigorov, Elizabeth Ivanova, et al. "Nanohardness Measurements of CdSiP2 and ZnGeP2 Chalcopyrite-Type Nonlinear Optical Crystals." Crystals 13, no. 8 (2023): 1164. http://dx.doi.org/10.3390/cryst13081164.

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We study the nanohardness and Young’s modulus of randomly oriented CdSiP2 (CSP) and ZnGeP2 (ZGP) single crystals, grown via the horizontal Bridgman method. CSP and ZGP are the only two pnictide chalcopyrites widely used as nonlinear optical crystals in the mid-IR part of the spectrum. Nanoindentation is employed in the continuous stiffness mode (45 Hz, 2 nm) using a Berkovich tip. Nanohardness values of 9.9 ± 0.2 GPa (Knoop hardness of 905 kg/mm2) for CSP and 11.5 ± 0.1 GPa (993 kg/mm2) for ZGP are derived. For Young’s modulus, we obtain 136 ± 2 GPa (CSP) and 150 ± 2 GPa (ZGP). The trend of in

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Gomes, Tiago Halyson de Oliveira, Welleson Feitosa Gazel, Emanuela Ferreira Goulart, Jennifer Lee Gonçalves, Gabriel Vargas Maia Chaves, and Lígia Luana Freire da Silva. "ÓBITOS DEVIDOS À SEPSE ESTREPTOCÓCICA NO BRASIL: ANÁLISE DE 13 ANOS." Revista ft 29, no. 143 (2025): 45–46. https://doi.org/10.69849/revistaft/ch10202502210945.

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Introdução: A sepse é uma síndrome caracterizada por uma resposta inflamatória exacerbada a uma infecção, levando à disfunção orgânica e risco elevado de morte. Fatores de risco como o uso de cateteres, sonda uretral, imunossupressão, comorbidades, infecções pré-existentes, resistência antimicrobiana e estado nutricional comprometido são determinantes importantes para o desenvolvimento da doença. Objetivos: O objetivo do presente trabalho é realizar o levantamento epidemiológico acerca dos óbitos por casos de septicemia estreptocócica no Brasil, em um período de 13 anos. Bem como realizar o le

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Kaye, S. B., J. Paul, J. Cassidy, et al. "Mature results of a randomized trial of two doses of cisplatin for the treatment of ovarian cancer. Scottish Gynecology Cancer Trials Group." Journal of Clinical Oncology 14, no. 7 (1996): 2113–19. http://dx.doi.org/10.1200/jco.1996.14.7.2113.

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PURPOSE In 1992, we reported the first results of a randomized study in ovarian cancer, comprising two doses of cisplatin and indicated a significant difference (P = .0008) in median survival. Four years later, we now describe the results of this trial. PATIENTS AND METHODS After a median follow-up of 4 years and 9 months, 115 of 159 cases of advanced ovarian cancer, originally randomized to receive six cycles of cyclophosphamide 750 mg/m2 and either a high dose (HD) of 100 mg/m2 cisplatin or a low dose (LD) of 50 mg/m2 (LD) cisplatin, have now died. RESULTS The overall survival for HD and LD

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Sawattep, Jeeranut, Thad A. Howard, Noppawan P. Morales, et al. "Single Nucleotide Polymorphism (SNP) Discovery within the UGT1A Gene Complex: Allelic Frequencies and Ethnic Differences." Blood 104, no. 11 (2004): 3780. http://dx.doi.org/10.1182/blood.v104.11.3780.3780.

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Abstract The UDP-glycosyltransferase (UGT1A) gene complex plays an important role in the hepatic metabolism of many chemicals, toxins, and drugs including bilirubin and acetaminophen. In this large gene complex that spans over 200kb, there are at least 13 different coding regions that can serve as exon 1, followed by a common sequence that contains exons 2–5. These variable exon 1 sequences confer different chemical specificities for binding compounds, while exons 2–5 provide glycosyltransferase function (glucuronidation) that enhances water solubility and excretion. Mutations and polymorphism

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Musso Ribeiro de Oliveira Souza, Chiara, Gustavo Ribeiro Lima, and Angélica Espinosa Miranda. "Blood-borne infections and pregnancies among women attending a sexual violence assistance center in Brazil: A 10-year retrospective study." PLOS ONE 18, no. 2 (2023): e0280419. http://dx.doi.org/10.1371/journal.pone.0280419.

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Introduction Sexually transmitted infections (STI) and pregnancy can be consequences of sexual violence. In Brazil, around 50% of women victims of sexual violence do not undergo STI prophylaxis or emergency contraception. Objectives To analyze socio-demographic and epidemiological profile, frequency of procedures performed, frequency of blood-borne infections (BBI), pregnancy, and legal abortion in women assisted by a sexual violence assistance center. Patients and methods This 10-year retrospective cohort study (2010–2019) describes the socio-demographic and epidemiological profile and freque

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Fischer, H., R. Kormann, T. Klüpfel, et al. "Ozone production and trace gas correlations during the June 2000 MINATROC intensive measurement campaign at Mt. Cimone." Atmospheric Chemistry and Physics Discussions 2, no. 5 (2002): 1509–43. http://dx.doi.org/10.5194/acpd-2-1509-2002.

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Abstract. An intensive measurement campaign was performed in June 2000 at the Mt. Cimone station (44°11' N -- 10°42' E, 2165 m asl, the highest mountain in the northern Italian Apennines) to study photochemical ozone production in the lower free troposphere. In general, average mixing ratios of important trace gases were not very high (121 ± 20 ppbv CO, 0.284 ± 0.220 ppbv NOx, 1.15 ± 0.8 ppbv NOy, 58 ± 9 ppbv O3), which indicates a small contribution by local pollution. This is supported by the analysis of volatile organic compounds (VOCs), that exhibit mean levels typical for background conti

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Benito, Gerardo, Yolanda Sanchez-Moya, Alicia Medialdea, et al. "Extreme Floods in Small Mediterranean Catchments: Long-Term Response to Climate Variability and Change." Water 12, no. 4 (2020): 1008. http://dx.doi.org/10.3390/w12041008.

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Climate change implies changes in the frequency and magnitude of flood events. The influence of climate variability on flooding was evaluated by an analysis of sedimentary (palaeofloods) and documentary archives. A 500-year palaeoflood record at Montlleó River (657 km2 in catchment area), eastern Spain, revealed up to 31 palaeofloods with a range of discharges of 20–950 m3 s−1, and with at least five floods exceeding 740–950 m3 s−1. This information contrasts with the available gauged flood registers (since year 1971) with an annual maximum daily discharge of 129 m3 s−1. Our palaeoflood datase

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อรัณย์ชนายุธ, จิณห์วรา, та อวิรุทธ์ ศรีสุธาพรรณ. "แนวทางการใช้เกณฑ์การประเมินแสงธรรมชาติที่มีผลต่อนาฬิกาชีวิตในประเทศไทย". Journal of Architectural/Planning Research and Studies (JARS) 18, № 1 (2021): 115–30. http://dx.doi.org/10.56261/jars.v18i1.236649.

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แนวทางการออกแบบและเกณฑ์ในการประเมินเรื่องแสงที่มีผลต่อนาฬิกาชีวิต (Circadian Lighting) ส่วนใหญ่เป็นข้อมูลที่มีการศึกษาและพัฒนามาจากต่างประเทศ ซึ่งยังไม่ได้มีการศึกษาถึงความสอดคล้องและเหมาะสมในการนำมาประยุกต์ใช้งานในประเทศไทย ดังนั้น งานวิจัยนี้จึงมีวัตถุประสงค์เพื่อประเมินการใช้เกณฑ์การออกแบบแสงธรรมชาติที่มีผลต่อนาฬิกาชีวิตในสภาพแสงอาทิตย์ของประเทศไทย เพื่อช่วยให้ผู้ออกแบบเกิดความเข้าใจในการใช้เกณฑ์มากขึ้น เห็นถึงผลการประเมินจากการใช้เกณฑ์ที่แตกต่างกัน และ เป็นแนวทางในการนำไปใช้ในงานออกแบบต่อไป โดยใช้แบบจำลองที่มีอัตราส่วน 1:1 1:2 และ 2:1 ภายใต้ท้องฟ้าครึ้มและท้องฟ้าโปร่งด้วยโปรแกรม DIALux evo

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Kolesnikov, E. A. "STUDY OF PSYCHOLOGICAL CHARACTERISTICS OF ADOLESCENTS TENDING TO VICTIMAL BEHAVIOR IN VIRTUAL SPACE." Bulletin of Udmurt University. Series Philosophy. Psychology. Pedagogy 29, no. 2 (2019): 148–59. http://dx.doi.org/10.35634/2412-9550-2019-29-2-148-159.

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The article considers a victimal behavior of teenagers in virtual space as a form of activity of teenagers in virtual space characterized by antisocial orientation in Internet communications and resulting in the formation of a status of the victim at a teenager. In an empirical research it was tracked that teenagers with high level of victimization, who display themselves in virtual space, are characterized by: a high level of acceptance of the Internet as living space, aspiration to stay in the Internet environment for a long time (U=92, р =, 042); they are focused on people’s assessment of t

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Buchholz, Christina, Melanie Kahle-Stephan, Juris J. Meier, and Michael A. Nauck. "Clinical Predictors of the Need for Further Treatment Escalation in Patients with Type 2 Diabetes on Basal Insulin Therapy – A Retrospective Observational Study." Experimental and Clinical Endocrinology & Diabetes 127, no. 10 (2019): 663–71. http://dx.doi.org/10.1055/a-0972-9700.

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Abstract Background/Aims The aim of this study was to identify clinical characteristics that distinguish patients who achieve sufficient glycaemic control with basal insulin and oral glucose-lowering medications from those who need treatment intensification. Patients/Methods 213 out of 1 042 consecutively hospitalized type 2-diabetic patients were treated with basal insulin/oral agents. After titration to fasting glucose target, in 156 patients (73.2%) continuation of basal insulin treatment was recommended, while in 57 (26.8%), intensification of treatment was necessary. We compared patients’

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Ma, Jianhong, Zhenxin Zhu, Xiao Chen, et al. "A cross-sectional survey of nutrition labelling use and its associated factors on parents of school students in Shanghai, China." Public Health Nutrition 21, no. 8 (2018): 1418–25. http://dx.doi.org/10.1017/s1368980018000332.

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AbstractObjectiveTo understand parents’ knowledge and use of nutrition labelling and to explore its associated factors.DesignCross-sectional survey.SettingTwo schools providing a nine-year educational programme in Putuo District, Shanghai, China, were selected for the study. Information was included on demographic data and knowledge of the Chinese Food Pagoda.SubjectsStudents and their parents (n 1770) participated in a questionnaire survey.ResultsOf questionnaires, 1766 were completed (response rate 99·8 %). Utilization rate of nutrition labelling was 19·3 %. Among 624 parents knowing nutriti

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Steen, R. W. J. "A comparison of soya-bean meal, fish meal and maize gluten feed as protein sources for calves offered grass silage ad libitum." Animal Science 54, no. 3 (1992): 333–39. http://dx.doi.org/10.1017/s000335610002078x.

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AbstractTwo experiments were carried out to evaluate extracted soya-bean meal, fish meal and maize gluten feed as protein supplements for calves offered grass silage ad libitum. The five treatments used in experiment 1 consisted of 1·4 kg per head daily of concentrate dry matter (DM) consisting of (g/kg) 50 molasses and 25 minerals and vitamins plus (1) 925 barley (B), (2) 700 B and 225 extracted soya-bean meal (SBM), (3) 785 B and 140 fish meal (FM), (4) 925 maize gluten feed (MGF) and (5) 2·25 kg DM per head daily of concentrate (1). Those used in experiment 2 consisted of 1·4 kg per head da

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Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics

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De Agustin, J. J., G. Añez, D. Reina-Sanz, et al. "AB1116 APREMILAST IN PSORIATIC ARTHRITIS. ULTRASOUND ANALYSIS (JOINT-ENTHESES-UNGUEAL INDEX) OF THE EFFICACY AND VARIABLES CORRELATION STUDY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1787–88. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1397.

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BackgroundWe conducted a study using ultrasonography (US) to evidence inflammatory changes (joint-enthesis-ungueal) in active PsA (aPsA) patients who started Apremilast (A) in clinical practice.ObjectivesObtain a 20, 50, 70 % reduction in the US index (UIC) at 12 months, and study correlation between variables.MethodsPhase IV, multicenter, prospective and open-label clinical trialconductedin 9 centresfrom 2018 to 2021. All patients signed the informed consent. Approval by the ethical committee was obtained, code PSA-PI-006421. PsA patients (≥ 2 swollen joints), ≥ 2 joint US synovitis and ≥ 1 U

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Cappellini, Maria Domenica, Norbert Gattermann, Vip Viprakasit, et al. "Transfusion History, Iron Chelation Practices and Status of Iron Overload across Various Transfusion-Dependent Anemias: Data from the Large- Scale, Prospective, 1-Year EPIC Trial." Blood 112, no. 11 (2008): 3880. http://dx.doi.org/10.1182/blood.v112.11.3880.3880.

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Abstract Background: The prospective, 1-yr multicenter EPIC trial evaluated the efficacy and safety of once-daily oral deferasirox (Exjade®) in more than 1700 patients (pts) with transfusion-dependent anemias. Data were collected from each patient at enrollment, providing an insight into transfusion history, body iron burden, and the nature and success of previous chelation therapy in a large group of pts with iron overload previously treated with chelation therapy. Methods: Enrolled pts were aged ≥2 yrs, had transfusion-dependent anemia and serum ferritin (SF) levels of ≥1000 ng/mL, or <10

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Chonabayashi, Kazuhisa, Masakatsu Hishizawa, Shin Kawamata, et al. "Direct Binding of Grb2 Is Required for Efficient Induction of Myeloproliferative Disease in Mice by ETV6/FLT3." Blood 114, no. 22 (2009): 2903. http://dx.doi.org/10.1182/blood.v114.22.2903.2903.

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Abstract Abstract 2903 Poster Board II-879 FMS-like tyrosine kinase 3 (FLT3), a class III receptor tyrosine kinase, is one of the most frequently mutated genes in hematological malignancies. The most common mutations of FLT3 are internal tandem duplications (ITDs) within the juxtamembrane domain: these mutations occur in 20% to 30% of patients with AML and are closely associated with a poor prognosis. In a small number of patients with myeloproliferative neoplasms (MPNs), FLT3 has been reported to fuse to ETV6 (TEL) and contribute to leukemogenesis, but the leukemogenic mechanism of ETV6/FLT3

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Eisfeld, Ann-Kathrin, Ralph Burkhardt, Daniel Teupser, et al. "HFE Genotype Is of Donor Origin and Does Not Correlate with Iron Overload Present in Patients after Allogeneic Stem Cell Transplantation." Blood 104, no. 11 (2004): 3684. http://dx.doi.org/10.1182/blood.v104.11.3684.3684.

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Abstract Introduction: A substantial proportion of European populations (10–40%) are heterozygous carriers (het) and 0.1–0.3% homozygos (homo) for the hemochromatosis gene (HFE). Patients (pts) with hematologic malignancies often receive multiple blood transfusions (BT). 228 pts undergoing allogeneic stem cell transplantation (SCT) at the University of Leipzig and their donors were screened for HFE. Furthermore, HFE genotype after SCT and body iron stores were correlated with BT and GVHD. Pts and methods: 228 pts (125 m/103 f; median age 46 years) transplanted from Jan, 2001-May, 2004 and thei

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Miloševski, Darko, Ranko Adjiski, and Emilija Fidančevska. "Liquid phase sintering of dense and porous composites obtained from industrial wastes." Macedonian Journal of Chemistry and Chemical Engineering 28, no. 2 (2009): 189. http://dx.doi.org/10.20450/mjcce.2009.210.

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Metallurgical slag and waste TV glass hawe been used for fabrication of ceramic-glass composite with a controlled porosity. A dense composite consisted of 70 wt% slag and 30 wt% TV glass sintered at 1000 ºC/2h, with the integral porosity of 16 %, has the E–modulus and bending strength of 26.0±1.6 GPa and 60.8±1.9 MPa, respectively. Slag with granulation of 0.125÷0.063 mm and 20 wt% TV glass, sintered at 950 ºC/2h possesses integral porosity of 37 % and E-modulus and bending strength of 11.86±2 GPa and 23.14±2 MPa, respectively, while the composite with the same composition but with porosity of

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Medić, Snežana, Cleo Anastassopoulou, Zagorka Lozanov-Crvenković, et al. "Incidence, Risk, and Severity of SARS-CoV-2 Reinfections in Children and Adolescents Between March 2020 and July 2022 in Serbia." JAMA Network Open 6, no. 2 (2023): e2255779. http://dx.doi.org/10.1001/jamanetworkopen.2022.55779.

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ImportanceDuring the COVID-19 pandemic, children and adolescents were massively infected worldwide. In 2022, reinfections became a main feature of the endemic phase of SARS-CoV-2, so it is important to understand the epidemiology and clinical impact of reinfections.ObjectiveTo assess the incidence, risk, and severity of pediatric SARS-CoV-2 reinfection.Design, Setting, and ParticipantsThis retrospective cohort study used epidemiologic data of documented SARS-CoV-2 infections from the surveillance database of the Institute for Public Health of Vojvodina. A total of 32 524 children and adolescen

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Ciancio, Alessia, Davide Giuseppe Ribaldone, Matteo Spertino, et al. "Who Should Not Be Surveilled for HCC Development after Successful Therapy with DAAS in Advanced Chronic Hepatitis C? Results of a Long-Term Prospective Study." Biomedicines 11, no. 1 (2023): 166. http://dx.doi.org/10.3390/biomedicines11010166.

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Background and aims: The identification of patients with Hepatitis C Virus (HCV)-positive advanced chronic liver disease (aCLD) successfully treated by Direct Acting Antiviral Agents (DAAs) who really benefit from Hepatocellular Carcinoma (HCC) surveillance programs is still a matter of debate. We performed a long-term prospective cohort study on F3-F4 HCV-positive patients achieving Sustained Virologic Response (SVR) after DAAs treatment in order to identify patients who can safely suspend surveillance. Methods: 1000 patients with HCV-positive aCLD obtaining SVR by DAAs from January 2015 to D

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Lozano, Miguel, Ana Galan, Roberto Mazzara, Laurence Corash, and Gines Escolar. "Leucocyte-Reduced Buffy Coat Platelet Concentrates (BCPC) Treated with INTERCEPT™ Stored up to 7 Days: Hemostatic Function in a Whole Blood Flow System." Blood 106, no. 11 (2005): 956. http://dx.doi.org/10.1182/blood.v106.11.956.956.

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Abstract Background: The risk of bacterial growth has limited the shelf life of platelet concentrates (PC) to 5 days. Modern platelet storage containers facilitate storage for up to 7 days, if bacterial contamination is prevented. INTERCEPT (Baxter, La Chatre, France; Cerus, Concord, CA) photochemical treatment (PCT) for pathogen reduction based on amotosalen (150μM) and UVA illumination (3 J/cm2) inactivates high titers of bacteria in PC (Transfusion2004; 44: 1496–1504). Adhesion and aggregation of platelets to injured vascular surfaces are critical aspects of platelet hemostatic function. In

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Dunlop, Hayley, Evelyn Fitzpatrick, Kevin Kurti, et al. "Participation of Patients From Racial and Ethnic Minority Groups in Phase 1 Early Cancer Drug Development Trials in the US, 2000-2018." JAMA Network Open 5, no. 11 (2022): e2239884. http://dx.doi.org/10.1001/jamanetworkopen.2022.39884.

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ImportanceDespite federal initiatives encouraging the enrollment of individuals from racial and ethnic minority groups in US clinical trials, no studies to date have specifically examined demographic disparities among participants in phase 1 drug development trials for patients with metastatic cancer.ObjectiveTo assess trends in the enrollment of patients from racial and ethnic minority groups in US phase 1 therapeutic drug trials for metastatic cancer from 2000 to 2018.Design, Setting, and ParticipantsIn this cross-sectional study, ClinicalTrials.gov was queried in July 2021 to identify compl

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Guo, Jun, Xiaoshi Zhang, Di Wu, et al. "First-line lenvatinib plus pembrolizumab versus placebo plus pembrolizumab in Chinese patients with unresectable or metastatic melanoma: Results from LEAP-003." Journal of Clinical Oncology 43, no. 16_suppl (2025): 9553. https://doi.org/10.1200/jco.2025.43.16_suppl.9553.

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9553 Background: Results of the global, phase 3 LEAP-003 study, showed that lenvatinib (len) + pembrolizumab (pembro) significantly improved PFS compared with pembro alone in participants (pts) with predominantly cutaneous melanoma at the first interim analysis, but this benefit was not maintained with additional follow-up and there was no improvement in OS. Previous studies have shown that mucosal and acral melanomas, which are the predominant subtypes in Chinese patients, may benefit from combination therapy. Here, we present results for Chinese participants (pts) enrolled in the LEAP-003 gl

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Linehan, C. J., D. P. Armstrong, P. T. Doyle, and F. Johnson. "A survey of water use efficiency on irrigated dairy farms in northern Victoria." Australian Journal of Experimental Agriculture 44, no. 2 (2004): 131. http://dx.doi.org/10.1071/ea02234.

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Water use efficiency (WUE) in irrigated dairy systems has been defined, in this paper, as the amount of milk (kg milk fat plus protein) produced from pasture per megalitre of water (irrigation plus effective rainfall). A�farm survey was conducted for the 1997–98 and 1998–99 seasons in the Goulburn Irrigation System (GIS) and Murray Irrigation System (MIS) when the irrigation water allocated to irrigators in the GIS was low (100–120% of water right compared with the MIS which was 130 and 200% of water right). These data were analysed in conjunction with information collected on the same farms i

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Oberti, R., F. Cámaraite, F. C. Hawthorne, and N. A. Ball. "Fluoro-aluminoleakeite, NaNa2(Mg2Al2Li)Si8O22F2, a new mineral of the amphibole group from Norra Kärr, Sweden: description and crystal structure." Mineralogical Magazine 73, no. 5 (2009): 817–24. http://dx.doi.org/10.1180/minmag.2009.073.5.817.

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AbstractFluoro-aluminoleakeite, ideally , is a new mineral of the amphibole group from Norra Kärr, Sweden (IMA-CNMMNC 2009-012). It occurs in a proterozoic alkaline intrusion that mainly comprises a fine-grained schistose agpaitic nepheline-syenite (grennaite). Fluoro- aluminoleakeite occurs as isolated prismatic crystals 0.10–2 mm long in a syenitic matrix. Crystals are light greenish-blue with a greenish-blue streak. It is brittle, has a Mohs hardness of 6 and a splintery fracture; it is non-fluorescent with perfect {110} cleavage, no observable parting, and has a calculated density of 3.14

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Дєдух, І. В., Т. Ю. Марченко, Ю. О. Лавриненко, А. С. Світлакова, С. В. Міщенко та В. Д. Марченко. "Ефективність дії сучасних інсектицидів в системі захисту посівів соняшнику від бавовникової совки (Helicoverpa armigera Hb) в умовах Півдня України". Аграрні інновації, № 30 (25 квітня 2025): 62–68. https://doi.org/10.32848/agrar.innov.2025.30.9.

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Мета – дослідити ефективність дії сучасних інсектицидів проти бавовникової совки (Helicoverpa armigera Hb) на гібриді соняшнику П64ЛЦ108 в умовах Одеської області. Методи Методологічною основою даного дослідження є: емпіричні (польові експерименти та спостереження; вимірювання показників об’єкту дослідження; порівняння впливу елементів агротехнологій), теоретичні (висунення гіпотези та формування висновків за результатами досліджень; статистичний; математичний. Результати. Середня чисельність бавовникової совки на посівах соняшнику за два роки дослідження до обробки препаратами в середньому ст

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Panova, I. E., E. V. Boiko, E. V. Samkovich, and V. G. Gvazav. "Isolated Transpupillary Photodynamic Therapy in Local Treatment of Choroidal Melanoma." Ophthalmology in Russia 22, no. 1 (2025): 159–68. https://doi.org/10.18008/1816-5095-2025-1-159-168.

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Objective: To evaluate the long-term results of local application of transpupillary photodynamic therapy (PDT) with chlorine photosensitizer in isolated organ-preserving treatment of uveal melanoma (UM) and to determine predictors of its effectiveness.Patients and methods. Retrospective analysis of transpupillary PDT efficacy in 38 patients (38 eyes) diagnosed with choroidal melanoma (CM) treated between 2016 and 2024. The median follow-up time was 24 months. The mean age was 62.77 ± 10.89 years. Distribution according to TNM: I (n = 12), IIA (n = 20), IIB (n = 6). According to ultrasound Dopp

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Lin, Timothy, Suqi Ke, Chen Hu, et al. "CTNI-43. A PHASE 1/2 STUDY OF LOW DOSE FRACTIONATED RADIATION THERAPY AS A CHEMOPOTENTIATOR OF SALVAGE TEMOZOLOMIDE FOR HIGH-GRADE GLIOMA." Neuro-Oncology 25, Supplement_5 (2023): v84—v85. http://dx.doi.org/10.1093/neuonc/noad179.0325.

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Abstract Cell-survival curves demonstrate low-dose radiation hypersensitivity, with steepest cell kill at 0.3-0.5 Gy/fx. This phase 1/2 study assessed the safety/efficacy of low-dose fractionated radiotherapy (LDFRT) as a chemopotentiator of TMZ in recurrent glioblastoma or anaplastic astrocytoma (AA) patients. Patients with recurrent glioblastoma/AA following standard-of-care therapy, &gt; 12 months from prior RT and &gt;2 months from prior TMZ were eligible for 0.5 Gy RT twice daily x10 fractions with concurrent TMZ (150-200 mg/m2), both delivered in 5 days of a 28-day cycle up to 6

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Pringle, Jamie S. M., Jonathan H. Doust, Helen Carter, Keith Tolfrey, and Andrew M. Jones. "Effect of pedal rate on primary and slow-component oxygen uptake responses during heavy-cycle exercise." Journal of Applied Physiology 94, no. 4 (2003): 1501–7. http://dx.doi.org/10.1152/japplphysiol.00456.2002.

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We hypothesized that a higher pedal rate (assumed to result in a greater proportional contribution of type II motor units) would be associated with an increased amplitude of the O2 uptake (V˙o 2) slow component during heavy-cycle exercise. Ten subjects (mean ± SD, age 26 ± 4 yr, body mass 71.5 ± 7.9 kg) completed a series of square-wave transitions to heavy exercise at pedal rates of 35, 75, and 115 rpm. The exercise power output was set at 50% of the difference between the pedal rate-specific ventilatory threshold and peakV˙o 2, and the baseline power output was adjusted to account for differ

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Rivera Teran, V., M. Pérez Rodríguez, D. Alpizar-Rodriguez, et al. "AB1229 SAFETY OF BIOSIMILAR ETANERCEPT IN THE TREATMENT OF RHEUMATIC DISEASES: DATA FROM THE MEXICAN ADVERSE EVENTS REGISTRY (BIOBADAMEX)." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1905.1–1906. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3819.

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Background:Access to biosimilar drugs in Mexico started on 2014. Although biosimilar drugs safety has proved comparability to originator drugs on trials, information about its safety on real-life data is limited.Objectives:To compare safety in terms of adverse events of biosimilar etanercept (BEt) to originator etanercept (OEt) using information from the Mexican Adverse Events Registry (BIOBADAMEX).Methods:BIOBADAMEX is a Mexican cohort that collects the information of biologic and biosimilar drugs used in patients with rheumatic diseases in public and private practice since 2016. Patients enr

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Faidah, A. N., and H. Shabrina. "Expressed sequence tag simple sequence repeats (EST-SSRs) mining and marker development from Leucaena leucocephala root transcriptome." IOP Conference Series: Earth and Environmental Science 959, no. 1 (2022): 012022. http://dx.doi.org/10.1088/1755-1315/959/1/012022.

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Abstract Leucaena leucocephala is a nitrogen-fixing legume and a fast-growing species used for various purposes, including food, medicine, and most recently, energy-source wood. Compared to other commonly planted legumes, this species has a high-stress tolerance, and only one recorded insect infestation. The transcriptome analysis revealed genes involved in the production of stress tolerance compounds in the root. In this study, we attempted to extract simple sequence repeats (SSRs) from the transcriptome data of L. leucocephala root to establish molecular markers. The SSRs mined from L. leuco

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Giné, Eva, Sílvia Beà, Alba Navarro, et al. "Risk of Central Nervous System (CNS) Involvement in Patients with Mantle Cell Lymphoma (MCL): Analysis of Clinico-Biological Factors in a Series of 283 Cases." Blood 124, no. 21 (2014): 1677. http://dx.doi.org/10.1182/blood.v124.21.1677.1677.

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Abstract Introduction: MCL is a mature B-cell neoplasm characterized by t(11;14) (q13;q32) and cyclin D1 (CCND1) overexpression. Molecular studies have revealed other alterations in cell-cycle regulation, DNA damage response and cell survival pathways, with a landscape of somatic mutations being recently identified. CNS involvement is a well known complication, occurring in 4-26% of MCL at five years, with an ominous significance. Although different clinical variables have been identified as risk factors for CNS infiltration, the biological parameters related to this complication have not been

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Krasnovidova, Anatasiya E., Olga I. Simonova, Vera P. Chernevich, Aleksandr V. Pakhomov, Aleksandra P. Reykh, and Aleksandr A. Pushkov. "Genotype-phenotype correlation in siblings with cystic fibrosis." Russian Pediatric Journal 26, no. 3 (2023): 159–67. http://dx.doi.org/10.46563/1560-9561-2023-26-3-159-167.

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Introduction. Despite the genetic counseling, families with cystic fibrosis (CF) patients and modern possibilities of prenatal molecular genetic screening, the occurrence of CF in more than one child in a family is not rare. The same genotype is expected to determine the specific phenotype in CF patients, especially in siblings. However, broad clinical heterogeneity could indicate the influence of secondary genetic factors on the course of the disease. The aim of the study is to examine the genotype-phenotype correlation and disease course features in CF siblings, including twins.

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Wagner, Matthias W., Patricia P. Rafful, Logi Vidarsson, and Birgit B. Ertl-Wagner. "MRI Volumetric Analysis of the Hypothalamus and Limbic System across the Pediatric Age Span." Children 10, no. 3 (2023): 477. http://dx.doi.org/10.3390/children10030477.

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Purpose: Literature is scarce regarding volumetric measures of limbic system components across the pediatric age range. The purpose of this study is to remedy this scarcity by reporting continuous volumetric measurements of limbic system components, and to provide consistent stratification data including age-related trajectories and sex-related differences in the pediatric age range in order to improve the recognition of structural variations that might reflect pathology. Methods: In this retrospective study, MRI sequences of children with normal clinical MRI examinations of the brain acquired

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Arranz, Isabel, Carsten Mischke, Joerg Stroka, et al. "Liquid Chromatographic Method for the Quantification of Zearalenone in Baby Food and Animal Feed: Interlaboratory Study." Journal of AOAC INTERNATIONAL 90, no. 6 (2007): 1598–609. http://dx.doi.org/10.1093/jaoac/90.6.1598.

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Abstract An interlaboratory trial for determination of zearalenone (ZON) in baby food and animal feed was conducted. The study involved 39 participants in 16 European Union member states, as well as Turkey, Uruguay, and China, representing a cross-section of industry, and official food control and research institutes. The method is based on immunoaffinity column cleanup followed by high-performance liquid chromatography using fluorimetry (HPLC-Fl). The test portion of the sample is extracted with methanolwater (75 + 25, v/v). The sample extract is filtered, diluted, and passed over an immunoaf

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Skripochnik, Edvard, Robert E. Michler, Viktoria Hentschel, and Siyamek Neragi-Miandoab. "The Efficacy and Outcome of Ministernotomy Compared to Those of Standard Sternotomy for Aortic Valve Replacement." ISRN Minimally Invasive Surgery 2014 (February 19, 2014): 1–6. http://dx.doi.org/10.1155/2014/254084.

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Background. Benefits of ministernotomy have been reported but not yet fully established in the current literature. Ministernotomy may be associated with less bleeding, less need for transfusion, and reduced hospital length of stay. Methods. We retrospectively evaluated 347 patients who underwent aortic valve replacement between 2007 and 2011 at our institution. Results. Standard sternotomy was performed in 303 patients (154 males, 50.8% and 149 females, 49.2%) and ministernotomy in 44 patients (13 males, 30% and 30 females, 70%); most of the patients in ministernotomy group were female (75%) (

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Traoré, Seydou, Winsowmé Aguiratou Linda Some, Cheick Ahmed Ouattara, Isidore T. Traoré, Ziemlé Clément Méda, and Gueswende Léon Blaise Savadogo. "Paiement additionnel malgré la gratuité des soins au Burkina Faso." Santé Publique Vol. 35, no. 3 (2023): 307–14. http://dx.doi.org/10.3917/spub.233.0307.

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Introduction : La gratuité des soins chez les enfants de moins de 5 ans au Burkina Faso a été introduite en 2016 afin de lever la barrière financière dans l’accès aux soins. Des dépenses de santé additionnelles subsisteraient malgré cette gratuité, ce qui peut compromettre l’accès aux services de santé des patients les plus démunis. Méthodes : Il s’agit d’une évaluation médico-économique partielle, notamment l’étude descriptive des dépenses de santé additionnelles payées par les parents. Nous avons consulté les reçus de paiement et les déclarations des parents. Résultats : Le revenu mensuel de

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Hunt, Ryan, Ayla Yalamanoglu, Jin Hyen Baek, et al. "A Mechanistic Investigation of the TTP-like State Associated with Intravenous Abuse of Opana® ER." Blood 126, no. 23 (2015): 3521. http://dx.doi.org/10.1182/blood.v126.23.3521.3521.

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Abstract Background: Since 2012, a growing list of case reports has emerged describing the occurrence of a TTP-like state following intravenous (i.v.) abuse of extended release oxymorphone (Opana® ER). The pathophysiology resulting from intravenous exposure to Opana® ER has demonstrated a spectrum of severity with unclear etiology, and approaches to treatment/management have ranged from early plasma exchange to supportive care alone. As a result these cases have spurred a collaborative investigation to better understand mechanisms of toxicity. Given the temporal relation between the reformulat

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Thompson, John A., D. Gary Gilliland, Josef T. Prchal, et al. "Effect of recombinant human erythropoietin combined with granulocyte/ macrophage colony-stimulating factor in the treatment of patients with myelodysplastic syndrome." Blood 95, no. 4 (2000): 1175–79. http://dx.doi.org/10.1182/blood.v95.4.1175.004k51_1175_1179.

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This randomized, placebo-controlled trial was designed to assess the efficacy and safety of therapy with granulocyte-macrophage colony-stimulating factor (GM-CSF) and erythropoietin (epoetin alfa) in anemic, neutropenic patients with myelodysplastic syndrome. Sixty-six patients were enrolled according to the following French–American–British classification: refractory anemia (20), refractory anemia with excess blasts (35), refractory anemia with ringed sideroblasts (9), and refractory anemia with excess blasts in transformation (2). Patients were stratified by their serum erythropoietin levels

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Simonneau, Gerald. "Nadroparin 0.3 mL Versus Enoxaparin 40 mg in the Prevention of Venous Thromboembolism in Abdominal Surgery for Colorectal Cancer: A Randomized Double-Blind Comparative Study." Blood 106, no. 11 (2005): 552. http://dx.doi.org/10.1182/blood.v106.11.552.552.

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Abstract Background: The relative benefit-to-risk ratio of various LMWH in the setting of colorectal cancer surgery has never been directly compared. Objective: We performed a multicenter, randomized, double-blind study to compare the efficacy and safety of enoxaparin 40 mg (4000 anti-Xa IU) and nadroparin 0.3 mL (2850 anti-Xa IU) in the prevention of venous thromboembolism (VTE) after colorectal cancer surgery. Methods: Patients undergoing elective colorectal adenocarcinoma resection under general anesthesia were recruited. They were randomized to receive once daily either nadroparin 0.3 mL o

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Rivera-Rodriguez, Noridza, Fernando Cabanillas, Carlos Montalban, et al. "The Pretreatment Absolute Lymphocyte Count (ALC), but Not the Absolute Monocyte Count (AMC) or ALC/AMC Ratio, Is an Independent Prognostic Factor in Aggressive Non-Hodgkin Lymphoma (aNHL)." Blood 120, no. 21 (2012): 1596. http://dx.doi.org/10.1182/blood.v120.21.1596.1596.

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Abstract Abstract 1596 Background: The IPI, which takes into consideration both host and tumor factors, is the standard method used to stratify aNHL into different risk categories. The IPI was derived in the pre-rituximab era and confirmed as valid in the Rituximab (R) era. The major mechanism of action of R appears to be through the host's immune system. Host factors related to the immune status have been recently recognized as significant in predicting outcome. The ALC, AMC, and ALC/AMC ratio were identified by Wilcox et al. as having an impact on both progression free survival (PFS) and ove

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Linares, Jose, Johannes Scholberg, Carlene Chase, Robert McSorley, and James Fergusson. "Integrative Approaches for Weed Management in Organic Citrus Orchards." HortScience 41, no. 4 (2006): 998A—998. http://dx.doi.org/10.21273/hortsci.41.4.998a.

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Lack of effective weed control may hamper organic citrus establishment. Cover crop/weed biomass (CCW) indices were used to assess the effectiveness of annual and perennial cover crops (CC) in reducing weed growth. The CCW values for perennial peanut (PP) were 0.06, 0.14, 0.4, and 0.5 during 2002, 2003, 2004, and 2005, respectively (very poor to poor weed control). Initial PP growth was slow and repeated mowing was required, but, over time, PP became more effective in controlling weeds. Weed biomass with sunn hemp was 0.3 Mg/ha in 2002 (CCW = 25, outstanding weed control) compared to 1.4 Mg/ha

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Ebarb, Sara, Richard Faris, Junmei Zhao, Sabrina Williams, and Kathryn Price. "153 Impacts of two energy sources (modified soy oil and medium chain triglycerides) on growth performance and health of nursery pigs." Journal of Animal Science 97, Supplement_2 (2019): 89. http://dx.doi.org/10.1093/jas/skz122.161.

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Abstract This study evaluated the effects of a modified soy oil (MSO) in diets with or without medium chain triglycerides from palm kernel oil (MCT). The study utilized 1,840 pigs (~19 d of age; 5.4 ± 0.2 kg), 10 pens/treatment, and ~22 pigs/pen. Two barns were blocked separately by pen location and randomly allocated to treatments. Treatments were arranged as a 2 × 4 factorial utilizing diets containing one of four levels of MSO (0, 0.15, 0.25, or 0.40%) and two levels of MCT [without vs with (0.50% d 0 to 7; 0.25% d 7 to 41)]. Pen weights were obtained on d 0, 7, 23, and 41 post-weaning, mor

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