Relevant bibliographies by topics / 18F-Fludarabine

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic '18F-Fludarabine'

Author: Grafiati
Published: 21 September 2024
Last updated: 31 July 2025

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Journal articles on the topic "18F-Fludarabine"

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Chantepie, Sylvain P., Narinée Hovhannisyan, Stéphane Guillouet, et al. "[18 F]-Fludarabine Positron Emission Tomography in Diffuse Large B-Cell Lymphoma (DLBCL) Patients: Results of a Phase I Study." Blood 126, no. 23 (2015): 3917. http://dx.doi.org/10.1182/blood.v126.23.3917.3917.

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Abstract Introduction: [18 F]-Fludarabine is a promising novel positron emission tomography (PET) radiotracer for lymphoid malignancies. The rationale for its development is the high selectivity of fludarabine uptake within lymphoid cells, irrespective of their cycle activity, and the fluorine atom within the molecule, which is replaced by [18 F] and leads to a positron emitting biomarker. Pre-clinical studies (Dhilly et al, Mol Imaging Biol 2014,16:118-26 ; Hovhannisyan et al, EJNMMI Res 2015,5:23) showed a marked tumor uptake in lymphoma-bearing mice. The aim of this study was to describe an
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Hovhannisyan, Narinée, Martine Dhilly, Martin Fidalgo, et al. "[18F]Fludarabine-PET in a murine model of multiple myeloma." PLOS ONE 12, no. 5 (2017): e0177125. http://dx.doi.org/10.1371/journal.pone.0177125.

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Hovhannisyan, Narinée, Martine Dhilly, Stéphane Guillouet, Michel Leporrier, and Louisa Barré. "Comparative Analysis between [18F]Fludarabine-PET and [18F]FDG-PET in a Murine Model of Inflammation." Molecular Pharmaceutics 13, no. 6 (2016): 2136–39. http://dx.doi.org/10.1021/acs.molpharmaceut.6b00050.

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Guillouet, Stéphane, Delphine Patin, Olivier Tirel, et al. "Fully Automated Radiosynthesis of 2-[18F]Fludarabine for PET Imaging of Low-Grade Lymphoma." Molecular Imaging and Biology 16, no. 1 (2013): 28–35. http://dx.doi.org/10.1007/s11307-013-0657-4.

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Hovhannisyan, Narinée, Fabien Fillesoye, Stéphane Guillouet, et al. "[18F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [18F]FDG in human xenograft models." Theranostics 8, no. 16 (2018): 4563–73. http://dx.doi.org/10.7150/thno.26754.

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Chantepie, Sylvain, Narinée Hovhannisyan, Stéphane Guillouet, et al. "18F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients." Journal of Nuclear Medicine 59, no. 9 (2018): 1380–85. http://dx.doi.org/10.2967/jnumed.117.206920.

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Dhilly, Martine, Stéphane Guillouet, Delphine patin, et al. "2-[18F]Fludarabine, a Novel Positron Emission Tomography (PET) Tracer for Imaging Lymphoma: a Micro-PET Study in Murine Models." Molecular Imaging and Biology 16, no. 1 (2013): 118–26. http://dx.doi.org/10.1007/s11307-013-0659-2.

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Francois, C., M. J. Santiago Ribeiro, B. Jamet, et al. "Résultats préliminaires de l’étude MyelofludaTEP évaluant la TEP à la [18F]Fludarabine pour le bilan initial et l’évaluation thérapeutique du myélome multiple." Médecine Nucléaire 48, no. 2 (2024): 47–48. http://dx.doi.org/10.1016/j.mednuc.2024.01.007.

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9

Magagnoli, Massimo, Rita Mazza, Sara Gandolfi, et al. "Result of FDG PET Imaging After Chemotherapy +/− Immunotherapy Is a Significant and Independent Prognostic Indicator of Outcome for Patients with Follicular Lymphoma: Survey From a Single Institution." Blood 118, no. 21 (2011): 2674. http://dx.doi.org/10.1182/blood.v118.21.2674.2674.

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Abstract Abstract 2674 Aim FDG positron emission tomography (PET) is the mainstay of response evaluation in some lymphoma subgroups such as DLBCL or HL according to Cheson criteria 2007. Due to its indolent behaviour, PET restaging has been poorly explored in Follicular Lymphoma (FL) Methods: The analysis was retrospectively conducted in pts with FL who underwent whole-body 18F-FDG-PET as part of response evaluation at the end of first line or savage treatment program at our institution from August 2001 to June 2010. Results: Seventy five patients were identified. Main clinical characteristics
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Lambert, Jonathan R., Jamshed B. Bomanji, Nichola Cooper, et al. "Pre-Transplant PET Status May Not Impact on Survival Following Reduced-Intensity Allogeneic Stem-Cell Transplant for Lymphoma. However, Post-Transplant Surveillance with PET May Be Important for Directing Immunotherapy." Blood 112, no. 11 (2008): 3256. http://dx.doi.org/10.1182/blood.v112.11.3256.3256.

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Abstract 18F-FDG PET (PET) imaging is now widely used in the management of patients with lymphoma, and has a recognised role in disease staging at diagnosis, determining response to treatment, and predicting response to autologous stem-cell transplantation (SCT). Reduced-intensity allogeneic SCT (RIT) has become an established therapy for patients with refractory or relapsed lymphoid malignancies, but the role of PET in RIT is unknown. We performed a prospective study to assess the role of PET in predicting outcome in RIT, and in directing intervention post-transplant. Sixty four patients with
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Dissertations / Theses on the topic "18F-Fludarabine"

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Hovhannisyan, Narinée. "[18F] Fludarabine pour l'imagerie TEP des lymphomes." Thesis, Normandie, 2018. http://www.theses.fr/2018NORMC412/document.

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Bien que l’utilité de la TEP au [18F]FDG soit confirmée pour le diagnostic et le suivi thérapeutique chez les patients atteints de lymphome, la spécificité de la captation du [18F]FDG a été mise en doute en raison de sa dépendance au métabolisme du glucose, qui peut augmenter dans des conditions bégnines comme les processus inflammatoire ou infectieux. Compte tenu de ces limites, un nucléoside a été développé en tant que nouvel outil pour l'imagerie TEP ([18F]fludarabine). Une radiosynthèse entièrement automatisée a été mise en place et des études précliniques ont été menées sur des modèles mu
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2

Rozenblum, Laura. "Nouveaux biomarqueurs d'imagerie pour la prise en charge des lymphomes primitifs du système nerveux central : études en TEP-IRM au 18F-FDG et à la 18F-FLUDARABINE." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS150.pdf.

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Le lymphome primitif du système nerveux central (LPSNC) est une pathologie au pronostic sombre, dont l'incidence est en hausse, notamment chez les patients âgés et immunocompétents. La démarche thérapeutique pour les patients atteints de LPSNC s'appuie sur l'évaluation de deux indicateurs pronostiques établis : l'âge et le performans status. Néanmoins, la nécessité d'améliorer les stratégies thérapeutiques actuelles, centrées sur une poly-chimiothérapie d'induction à base de méthotrexate à haute dose suivie potentiellement par un traitement d'entretien, a suscité un intérêt croissant dans l'id
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Patin, Delphine. "Le radiopharmaceutique en TEP : imagerie des lymphomes non-Hodgkiniens avec la [18F]Fludarabine ; synthèse, radiosynthèse et évaluation in vivo d’un procédé de vectorisation." Caen, 2013. http://www.theses.fr/2013CAEN2087.

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Dans le but de développer un traceur spécifique des lymphomes non-Hodgkiniens pour l’imagerie TEP, nous nous sommes intéressés à la radiosynthèse de la Fludarabine, médicament destiné au traitement des maladies lymphoprolitératives. Nous avons mis au point le marquage au fluor-18 et réalisé son automatisation sur un appareil commercial. L’évaluation in vivo à partir d’études précliniques a montré que la [18F]Fludarabine présentait un meilleur contraste que le [18F]FDG et pourrait être utilisée pour le diagnostic et le suivi des lymphomes non-Hodgkiniens. Dans une seconde partie, nous nous somm
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