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Journal articles on the topic '2+1-route'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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1

O'Connor, Joseph M., Kristin Hiibner, Rich Merwin, Peter K. Gantzel, Bella S. Fong, Melanie Adams, and Arnold L. Rheingold. "[2 + 2 + 1] Alkyne Cyclotrimerizations: A Metallacyclopentadiene Route to Fulvenes." Journal of the American Chemical Society 119, no. 15 (April 1997): 3631–32. http://dx.doi.org/10.1021/ja970007p.

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2

Al Dulayymi, Ahmad R., and Mark S. Baird. "A flexible route to 1-bromo-2-alkylcyclopropenes." Journal of the Chemical Society, Perkin Transactions 1, no. 12 (1994): 1547. http://dx.doi.org/10.1039/p19940001547.

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3

Trofimov, Boris, Al’bina Mikhaleva, Andrey Ivanov, Elena Skital’tseva, Igor’ Ushakov, and Alexander Vasil’tsov. "An Efficient Route to 1-Vinylpyrrole-2-carbaldehydes." Synthesis 2009, no. 04 (January 12, 2009): 587–90. http://dx.doi.org/10.1055/s-0028-1083312.

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4

Likhatchev, D., S. Granados-Fócil, R. Gaviño, M. Canseco, and L. Alexandrova. "Low-Temperature Route to 1, 2-Benzoylenebenzimidazole Ladder Structure." High Performance Polymers 11, no. 4 (December 1999): 405–15. http://dx.doi.org/10.1088/0954-0083/11/4/306.

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5

Orlek, Barry S. "A Stereoselective Route to trans-1-Arylthio-2-aminoindanes." Synlett 1996, no. 05 (May 1996): 477–78. http://dx.doi.org/10.1055/s-1996-5454.

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6

Imramovský, Aleš, Juana M. Férriz, Karel Pauk, Martin Krátký, and Jarmila Vinšová. "Synthetic Route for the Preparation of 2-Hydroxy-N-[1-(2-hydroxyphenylamino)-1-oxoalkan-2-yl]benzamides." Journal of Combinatorial Chemistry 12, no. 4 (July 12, 2010): 414–16. http://dx.doi.org/10.1021/cc900168s.

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7

Tsuge, Otohiko, Shuji Kanemasa, and Hiroyuki Suga. "Synthesis of 2-(1-Phosphorylalkyl)- and 2-(1-Alkenyl)furans through Nitrile Oxide Cycloaddition Route." Bulletin of the Chemical Society of Japan 61, no. 6 (June 1988): 2133–46. http://dx.doi.org/10.1246/bcsj.61.2133.

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8

Boga, Carla, Diego Savoia, Claudio Trombini, and Achille Umani-Ronchi. "A Short Route to 2-(6-Methoxycarbonylhexyl)-cyclopent-2-en-1-one." Synthesis 1986, no. 03 (1986): 212–13. http://dx.doi.org/10.1055/s-1986-31618.

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9

Khoroshilov, Gennadiy E., Natalia M. Tverdokhleb, Vladimir S. Brovarets, and Eugene V. Babaev. "Simple stepwise route to 1-substituted 2-amino-3-ethoxycarbonylindolizines." Tetrahedron 69, no. 21 (May 2013): 4353–57. http://dx.doi.org/10.1016/j.tet.2013.02.049.

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10

Binns, Malcolm R., Richard K. Haynes, Dale E. Lambert, and Paul A. Schober. "A route to prostaglandin precursors from 1-(phenylthio)-2-octenyllithium." Tetrahedron Letters 26, no. 28 (January 1985): 3385–88. http://dx.doi.org/10.1016/s0040-4039(00)98304-7.

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11

Koren, Andrei O., Pavel N. Gaponik, Oleg A. Ivashkevich, and Tamara B. Kovalyova. "A New Route to 1-Alkyltetrazoles: via 2-tert-Butyltetrazoles." Mendeleev Communications 5, no. 1 (January 1995): 10–11. http://dx.doi.org/10.1070/mc1995v005n01abeh000435.

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12

Zammattio, F., J. D. Brion, P. Ducrey, and G. Le Baut. "New Route to Styrylchromones via [1-(2-Hydroxybenzoyl)alkylidene]triphenylphosphoranes." Synthesis 1992, no. 04 (1992): 375–76. http://dx.doi.org/10.1055/s-1992-26115.

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13

AL DULAYYMI, A. R., and M. S. BAIRD. "ChemInform Abstract: A Flexible Route to 1-Bromo-2-alkylcyclopropenes." ChemInform 25, no. 43 (August 18, 2010): no. http://dx.doi.org/10.1002/chin.199443092.

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14

Jiang, Jun, and Gordon W. Gribble. "A DIRECT LITHIATION ROUTE TO 2-ACYL-1-(PHENYLSULFONYL)INDOLES." Synthetic Communications 32, no. 13 (January 2002): 2035–40. http://dx.doi.org/10.1081/scc-120004854.

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15

Voronkov, M. G., S. V. Kirpichenko, A. T. Abrosimova, and A. I. Albanov. "A novel synthetic route to 1-aza-2-silacyclopentane derivatives." Journal of Organometallic Chemistry 406, no. 1-2 (March 1991): 87–89. http://dx.doi.org/10.1016/0022-328x(91)83173-2.

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16

Kraus, George A., and Jacqueline M. Applegate. "A photochemical route to 1-oxa-2-sila-4-cyclopentenes." Journal of Photochemistry and Photobiology A: Chemistry 77, no. 2-3 (January 1994): 169–71. http://dx.doi.org/10.1016/1010-6030(94)80040-5.

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17

Lennon, Ian C., and James A. Ramsden. "An Efficient Catalytic Asymmetric Route to 1-Aryl-2-imidazol-1-yl-ethanols." Organic Process Research & Development 9, no. 1 (January 2005): 110–12. http://dx.doi.org/10.1021/op049838n.

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18

Piotrowski, David W. "A Concise Route to Novel 1-Aryl and 1-Pyridyl-2-Azabicyclo[2.1.1]hexanes." Synlett 1999, no. 7 (July 1999): 1091–93. http://dx.doi.org/10.1055/s-1999-2775.

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19

Netto-Ferreira, J. C., V. Wintgens, and J. C. Scaiano. "Photochemistry of 1-hydroxy-2-indanones: an alternative route to photoenols." Journal of the Brazilian Chemical Society 8, no. 4 (1997): 427–31. http://dx.doi.org/10.1590/s0103-50531997000400017.

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20

Gazvoda, Martin, Marko Krivec, Zdenko Časar, and Janez Košmrlj. "En Route to 2-(Cyclobuten-1-yl)-3-(trifluoromethyl)-1H-indole." Journal of Organic Chemistry 83, no. 4 (February 7, 2018): 2486–93. http://dx.doi.org/10.1021/acs.joc.8b00100.

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21

Kuo, Cheng-Han, Jun-Ren Huang, Hui-Ru Chen, Pei-Yu Chen, Chien-Hung Lin, and Lee-Gin Lin. "25,26-Dialkoxycalix[4]arenes. Part 2: 1-Alkoxy-3-benzoyloxy route." Tetrahedron 67, no. 21 (May 2011): 3936–44. http://dx.doi.org/10.1016/j.tet.2011.03.048.

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22

Shagun, L. G., I. A. Dorofeev, I. A. Tokareva, V. I. Smirnov, and M. G. Voronkov. "Photolysis of 2-iodo-1-phenylethanone: A new route to polyphenylenes." Russian Journal of Organic Chemistry 46, no. 4 (April 2010): 590–91. http://dx.doi.org/10.1134/s1070428010040263.

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23

Niclas, H. J., and B. Góhrmann. "A Novel Synthetic Route to 2-Aryl-2H-Benzotriazole 1-Oxides." Synthetic Communications 19, no. 11-12 (July 1989): 2141–49. http://dx.doi.org/10.1080/00397918908052609.

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24

Peng, Ai-Yun, Xin-Ying Zhang, and Yi-Xiang Ding. "A convenient and applicable route to synthesize 2-(1-alkynyl)phenylphosphonates." Heteroatom Chemistry 16, no. 6 (2005): 529–34. http://dx.doi.org/10.1002/hc.20156.

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25

ORLEK, B. S. "ChemInform Abstract: A Stereoselective Route to trans-1-Arylthio-2-aminoindans." ChemInform 27, no. 36 (August 5, 2010): no. http://dx.doi.org/10.1002/chin.199636096.

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26

Casiraghi, Giovanni, Mara Cornia, Giovanna Gasparri Fava, Marisa Ferrari Belicchi, and Lucia Zetta. "A highly stereoselective route to 1-C-(2-hydroxyaryl)-alditol derivatives." Carbohydrate Research 186, no. 2 (March 1989): 207–15. http://dx.doi.org/10.1016/0008-6215(89)84035-2.

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27

Trofimov, Boris A., Lyubov' N. Sobenina, Al'bina I. Mikhaleva, Ol'Ga V. Petrova, Vladislav N. Drichkov, Igor A. Ushakov, Ol'Ga A. Tarasova, Darya-Suren D. Toryashinova, Yuriy Yu Rusakov, and Leonid B. Krivdin. "Facile coupling of 2-(1-ethylthioethenyl)pyrroles with amines: A route to 2-(1-aminoethenyl)pyrroles and 1-amino-3-iminopyrrolizines." Journal of Heterocyclic Chemistry 44, no. 3 (May 2007): 505–13. http://dx.doi.org/10.1002/jhet.5570440301.

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28

Kirkiacharian, B. S., and P. G. Koutsourakis. "Hydroborations: A New Efficient Route to 1-Organo-2-indanones from 1-Alkyl(aryl)indenes." Synthesis 1990, no. 09 (1990): 815–16. http://dx.doi.org/10.1055/s-1990-27023.

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29

Tarleton, Mark, and Adam McCluskey. "A flow chemistry route to 2-phenyl-3-(1H-pyrrol-2-yl)propan-1-amines." Tetrahedron Letters 52, no. 14 (April 2011): 1583–86. http://dx.doi.org/10.1016/j.tetlet.2011.01.096.

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30

Huang, Long, Xuehui Liu, Duntie Zhang, Chenghao Luo, Jing Zhang, Yikun Chen, and Yuefa Gong. "A straightforward route to alkyl 5‐arylthiophene ‐2‐thiocarboxylates from alkyl 2‐aroyl ‐1‐chlorocyclopropanecarboxylates." Journal of Heterocyclic Chemistry 58, no. 3 (February 9, 2021): 882–91. http://dx.doi.org/10.1002/jhet.4225.

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31

Reddy, Maddi Sridhar, Nuligonda Thirupathi, and Yalla Kiran Kumar. "A quick and efficient route to substituted quinolines by electrophilic cyclization of 1-(2-aminoaryl)-2-yn-1-ols." RSC Advances 2, no. 9 (2012): 3986. http://dx.doi.org/10.1039/c2ra20213a.

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32

Sadykov, Evgeny, Natalya Lobanova, and Valery Stankevich. "Base-Mediated Addition of 1-(2-Hydroxyalkyl)pyrroles to Acetylene: Atom-Economic Route to 1-[2-(Vinyloxy)alkyl]pyrroles." Synthesis 47, no. 05 (December 15, 2014): 672–78. http://dx.doi.org/10.1055/s-0034-1378940.

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33

Khoroshilov, Gennadiy E., Natalia M. Tverdokhleb, Vladimir S. Brovarets, and Eugene V. Babaev. "ChemInform Abstract: Simple Stepwise Route to 1-Substituted 2-Amino-3-ethoxycarbonylindolizines." ChemInform 44, no. 38 (August 30, 2013): no. http://dx.doi.org/10.1002/chin.201338160.

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34

Jiang, Jun, and Gordon W. Gribble. "ChemInform Abstract: A Direct Lithiation Route to 2-Acyl-1-(phenylsulfonyl)indoles." ChemInform 33, no. 48 (May 18, 2010): no. http://dx.doi.org/10.1002/chin.200248119.

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35

KOREN, A. O., P. N. GAPONIK, O. A. IVASHKEVICH, and T. B. KOVALYOVA. "ChemInform Abstract: A New Route to 1-Alkyltetrazoles via 2-tert-Butyltetrazoles." ChemInform 26, no. 26 (August 17, 2010): no. http://dx.doi.org/10.1002/chin.199526143.

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36

ZAMMATTIO, F., J. D. BRION, P. DUCREY, and G. LE BAUT. "ChemInform Abstract: New Route to Styrylchromones via (1-(2-Hydroxybenzoyl)alkylidene) triphenylphosphoranes." ChemInform 23, no. 33 (August 21, 2010): no. http://dx.doi.org/10.1002/chin.199233188.

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37

VORONKOV, M. G., S. V. KIRPICHENKO, A. T. ABROSIMOVA, and A. I. ALBANOV. "ChemInform Abstract: A Novel Synthetic Route to 1-Aza-2-silacyclopentane Derivatives." ChemInform 22, no. 25 (August 23, 2010): no. http://dx.doi.org/10.1002/chin.199125200.

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38

Pattingre, Sophie, and Beth Levine. "Bcl-2 Inhibition of Autophagy: A New Route to Cancer?: Figure 1." Cancer Research 66, no. 6 (March 15, 2006): 2885–88. http://dx.doi.org/10.1158/0008-5472.can-05-4412.

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39

Tilley, Jefferson W., David L. Coffen, Beatrice H. Schaer, and Joan Lind. "Palladium-catalyzed carbonyl insertion route to pyrido[2-1-b]quinazoline derivatives." Journal of Organic Chemistry 52, no. 12 (June 1987): 2469–74. http://dx.doi.org/10.1021/jo00388a023.

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40

Pohmakotr, Manat, and Auntika Takampon. "Destannylative acylation of 1-[(2-methoxyethoxy)methoxy]-2-(phenylsulfonyl)-2-(tributylstannyl)cyclopropane: A novel route to 3-acylfurans." Tetrahedron Letters 37, no. 26 (June 1996): 4585–88. http://dx.doi.org/10.1016/0040-4039(96)00852-0.

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41

Rayabarapu, Dinesh Kumar, Kanak Kanti Majumdar, Thota Sambaiah, and Chien-Hong Cheng. "Unusual 1,4-Addition of 2-Pyridyl Carboxylates to Benzynes: A Convenient Route to 1-(2-Acylphenyl)-2-pyridones." Journal of Organic Chemistry 66, no. 10 (May 2001): 3646–49. http://dx.doi.org/10.1021/jo010162t.

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42

Petrova, Olga V., Elena F. Sagitova, Igor A. Ushakov, Lyubov N. Sobenina, Al'bina I. Mikhaleva, and Boris A. Trofimov. "Reaction of 2-(2,2-dicyano-1-ethylsulfanylethenyl)pyrroles with aniline: a route to 1-anilino-3-iminopyrrolizine-2-carbonitriles and 2-(1-anilino-2,2-dicyanoethenyl)pyrroles." Journal of Sulfur Chemistry 36, no. 2 (December 13, 2014): 145–54. http://dx.doi.org/10.1080/17415993.2014.987277.

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43

Takahashi, Michiyasu, and Kunio Ogasawara. "Lipase-Mediated Resolution of trans-1-Azidoindan-2-ol: A New Route to Optically Pure cis-1-Aminoindan-2-ol." Synthesis 1996, no. 08 (August 1996): 954–58. http://dx.doi.org/10.1055/s-1996-4328.

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44

Piotrowski, David W. "ChemInform Abstract: A Concise Route to Novel 1-Aryl and 1-Pyridyl-2-azabicycylo[2.1.1]hexanes." ChemInform 30, no. 43 (June 13, 2010): no. http://dx.doi.org/10.1002/chin.199943109.

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45

Liu, Ligong, Ken D. Johnstone, Jon K. Fairweather, Keith Dredge, and Vito Ferro. "An Improved Synthetic Route to the Potent Angiogenesis Inhibitor Benzyl Manα(1→3)-Manα(1→3)-Manα(1→3)-Manα(1→2)-Man Hexadecasulfate." Australian Journal of Chemistry 62, no. 6 (2009): 546. http://dx.doi.org/10.1071/ch09015.

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Abstract:

An improved synthetic route to α(1→3)/α(1→2)-linked mannooligosaccharides has been developed and applied to a more efficient preparation of the potent anti-angiogenic sulfated pentasaccharide, benzyl Manα(1→3)-Manα(1→3)-Manα(1→3)-Manα(1→2)-Man hexadecasulfate, using only two monosaccharide building blocks. Of particular note are improvements in the preparation of both building blocks and a simpler, final deprotection strategy. The route also provides common intermediates for the introduction of aglycones other than benzyl, either at the building block stage or after oligosaccharide assembly. The anti-angiogenic activity of the synthesized target compound was confirmed via the rat aortic assay.

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46

Ivanov, A. V., V. S. Shcherbakova, I. A. Ushakov, L. N. Sobenina, O. V. Petrova, A. I. Mikhaleva, and B. A. Trofimov. "2-(1-Hydroxypropyn-2-yl)-1-vinylpyrroles: the first successful Favorsky ethynylation of pyrrolecarbaldehydes." Beilstein Journal of Organic Chemistry 11 (February 10, 2015): 228–32. http://dx.doi.org/10.3762/bjoc.11.25.

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Abstract:

1-Vinylpyrrole-2-carbaldehydes react with acetylene at atmospheric pressure in a NaOH/EtOH/DMSO system at 7–10 °C to afford 2-(1-hydroxypropyn-2-yl)-1-vinylpyrroles in 53–94% yield. Thus, the first base-mediated direct ethynylation of pyrrolecarbaldehydes with free acetylene under modified conditions of the Favorsky reaction has been implemented to pave an expedient route to important biomolecules containing a pyrrole ring.

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47

Su, Qiang, Jian Wei Guo, Chu Fen Yang, and Ying De Cui. "Facile Synthesis of N-{2-[4-(2-Pyrimidinyl)-1-Piperazinyl]ethyl} Adamantane-1-Carboxamide." Applied Mechanics and Materials 117-119 (October 2011): 1319–22. http://dx.doi.org/10.4028/www.scientific.net/amm.117-119.1319.

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Abstract:

A facile method for the synthesis of N-{2-[4-(2-pyrimidinyl)-1-piperazinyl]ethyl} adamantane-1-carboxamide(Adatanserin) was developed by using 2-chloropyrimidine and adamantanecarbonyl chloride as the starting material via amidation and N-alkylation, using convergent route to reduce workups and steps in a good yield. The structures of compounds were confirmed by IR spectral, 1HNMR and elemental analyses.

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48

Somei, Masanori, Toshiya Kawasaki, Atsushi Kodama, Tokiko Nishida, and Kazuhisa Shimizu. "Preparation of 1-Hydroxyindole Derivatives and a New Route to 2-Substituted Indoles." HETEROCYCLES 32, no. 2 (1991): 221. http://dx.doi.org/10.3987/com-90-5647.

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49

Butin, Alexander V., Sergey K. Smirnov, Tatyana A. Stroganova, Wolfgang Bender, and Gennady D. Krapivin. "Simple route to 3-(2-indolyl)-1-propanones via a furan recyclization reaction." Tetrahedron 63, no. 2 (January 2007): 474–91. http://dx.doi.org/10.1016/j.tet.2006.10.056.

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50

Katritzky, Alan R., Guifen Zhang, and Linghong Xie. "Novel Route to Functionalized IndansviaFormal [3 + 2] Cycloadditions of 1-Benzylbenzotriazoles with Alkenes." Synthetic Communications 27, no. 14 (July 1997): 2467–78. http://dx.doi.org/10.1080/00397919708004110.

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