Log in

Relevant bibliographies by topics / 2-amino-4-chloro-6- methylpyrimidine

Contents

Journal articles

Academic literature on the topic '2-amino-4-chloro-6- methylpyrimidine'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic '2-amino-4-chloro-6- methylpyrimidine.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "2-amino-4-chloro-6- methylpyrimidine"

1

Afrough, T., M. Bakavoli, and H. Eshghi. "Synthesis and characterisation of new 3-methyl-6-[1-(pyrimidin-4-yl)ethyl]-5H-pyrimido[5,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivatives." Journal of Chemical Research 41, no. 7 (2017): 376–79. http://dx.doi.org/10.3184/174751917x14967701766978.

Full text

Abstract:

A new series of 3-methyl-6-[1-(pyrimidin-4-yl)ethyl]-5 H-pyrimido[5,4- e][1,2,4]triazolo[3,4- b][1,3,4]thiadiazine derivatives was synthesised through the condensation reaction of 5-bromo-4-[1-(5-bromo-2,6-dichloropyrimidin-4-yl)ethyl]-2-chloro-6-methylpyrimidine and 4-amino-5-methyl-4 H-1,2,4-triazole-3-thiol.

APA, Harvard, Vancouver, ISO, and other styles

2

KHADIGA, M. GHONBIM, EL-TELBANY FARAG, and YOUSSEF KHAIRIA. "Synthesis and Evaluation of some 2-, 4- and 2,4- Di-substituted.-6-methylpyrimidine Derivatives for Antimicrobial Activity." Journal of Indian Chemical Society Vol. 63, Oct 1986 (1986): 914–17. https://doi.org/10.5281/zenodo.6302313.

Full text

Abstract:

Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt <em>Manuscript received</em> <em>23 September 1986, accepted 2 August 1986</em> The reaction of 2-amino-4-cbloro-, 4-amino-2-chloro- and 2,4-dichloro-6-methylpyrimidines with primary aromatic amines under acidic conditions is presented. 2-, and 4-<sup>\(\omega\)</sup>-substituted-thioureido-6-methylpyrimidines were synthesised via the reaction of 2-amino-and 4-amino-6-metbylpyrimidine derivatives with arylisocyanates. Six compounds were evaluated for their antimicrobial activity and most of them sh

APA, Harvard, Vancouver, ISO, and other styles

3

Guruswamy, Vinay, Veeresh Bantal, and Mallesha Lingappa. "Anticonvulsant activity of 2-amino-4-chloro-6-methyl pyrimidine derivatives: synthesis and characterization." Research Journal of Chemistry and Environment 25, no. 8 (2022): 35–43. http://dx.doi.org/10.25303/258rjce3543.

Full text

Abstract:

A series of new 2-amino-4-chloro-6-methylpyrimidine derivatives, 3(a-f) was synthesized by using different aryl aldehydes. The synthesized compounds were characterized by FT-IR and 1H NMR spectral studies. The maximal electroshock seizure (MES) model was used for anticonvulsant activity and phenytoin was used as standard drug. The rotorod test for neurotoxic effects was determined. Compound 3e was found to be most potent of this series. The compound 3e showed 65.10% protection in comparison to phenytoin which completely inhibited the convulsions produced by electro-convulsometer, Similarly, co

APA, Harvard, Vancouver, ISO, and other styles

4

Jayavarthanan, T., N. Sundaraganesan, M. Karabacak, M. Cinar, and M. Kurt. "Vibrational spectra, UV and NMR, first order hyperpolarizability and HOMO–LUMO analysis of 2-amino-4-chloro-6-methylpyrimidine." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 97 (November 2012): 811–24. http://dx.doi.org/10.1016/j.saa.2012.07.064.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Becker, Irwin. "Preparation of pyrimidine derivatives as potential medicinal agents by the reaction of 2-amino-4-chloro-6-methylpyrimidine with primary and secondary amines." Journal of Heterocyclic Chemistry 42, no. 7 (2005): 1289–95. http://dx.doi.org/10.1002/jhet.5570420707.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Gerhardt, Valeska, and Michael Bolte. "6-Chloroisocytosine and 5-bromo-6-methylisocytosine: again, one or two tautomers present in the same crystal?" Acta Crystallographica Section C Structural Chemistry 72, no. 1 (2016): 84–93. http://dx.doi.org/10.1107/s2053229615024080.

Full text

Abstract:

It is well known that pyrimidin-4-one derivatives are able to adopt either the 1H- or the 3H-tautomeric form in (co)crystals, depending on the coformer. As part of ongoing research to investigate the preferred hydrogen-bonding patterns of active pharmaceutical ingredients and their model systems, 2-amino-6-chloropyrimidin-4-one and 2-amino-5-bromo-6-methylpyrimidin-4-one have been cocrystallized with several coformers and with each other. Since Cl and Br atoms both have versatile possibilities to interact with the coformers, such asviahydrogen or halogen bonds, their behaviour within the cryst

APA, Harvard, Vancouver, ISO, and other styles

7

Reddy, Gajjala Raghavendra, Chinta Raveendra Reddy, Gopireddy Venkata Subba Reddy, et al. "Synthesis of New 4-Chloro-6-Methylpyrimidin-2-yl-Aminophosphonates as Potential DU145 and A549 Cancer Cell Inhibitors." Letters in Drug Design & Discovery 17, no. 4 (2020): 396–410. http://dx.doi.org/10.2174/1570180816666190329223207.

Full text

Abstract:

: A series of new α-aminophosphonates containing potential anticancer active 4-chloro-6- methylpyrimidin-2-amino pharmacophore were synthesized. Background: α-Aminophosphonates are of growing interest to the researchers due to their biological activities. Besides aminophosphoryl functionality, which is responsible for the vital activity, incorporation of a captivating pharmacophore on it will definitely enrich its activity. Objective: Erstwhile many of the reported α-aminophosphonates impregnated with bioactive heterocycles like quinazoline, chromene, pyrazole, furan and thiophene were used as

APA, Harvard, Vancouver, ISO, and other styles

8

Sangavi, Marimuthu, Narayanasamy Kumaraguru, Ray J. Butcher, and Colin D. McMillen. "Hydrogen-bonding interactions in 5-fluorocytosine–urea (2/1), 5-fluorocytosine–5-fluorocytosinium 3,5-dinitrosalicylate–water (2/1/1) and 2-amino-4-chloro-6-methylpyrimidine–6-chloronicotinic acid (1/1)." Acta Crystallographica Section C Structural Chemistry 80, no. 2 (2024). http://dx.doi.org/10.1107/s2053229624000615.

Full text

Abstract:

Three new compounds, namely, 5-fluorocytosine–urea (2/1), 2C4H4FN3O·CH4N2O, (I), 5-fluorocytosine–5-fluorocytosinium 3,5-dinitrosalicylate–water (2/1/1), 2C4H4FN3O·C4H5FN3O+·C7H2N2O7 −·H2O, (II), and 2-amino-4-chloro-6-methylpyrimidine–6-chloronicotinic acid (1/1), C6H4ClNO2·C5H6ClN3, (III), have been synthesized and characterized by single-crystal X-ray diffraction. In compound (I), 5-fluorocytosine (5FC) molecules A and B form two different homosynthons [R 2 2(8) ring motif], one formed via N—H...O hydrogen bonds and the second via N—H...N hydrogen bonds. In addition to this interaction, a s

APA, Harvard, Vancouver, ISO, and other styles

9

Nuridayanti, Che Khalib, Thanigaimani Kaliyaperumal, Arshad Suhana, and Abdul Razak Ibrahim. "Supramolecular Cocrystal of 2-Amino-4-Chloro-6- Methylpyrimidine with 4-Methylbenzoic Acid: Synthesis, Structural Determinations and Quantum Chemical Investigations." October 4, 2015. https://doi.org/10.5281/zenodo.1110257.

Full text

Abstract:

The 1:1 cocrystal of 2-amino-4-chloro-6- methylpyrimidine (2A4C6MP) with 4-methylbenzoic acid (4MBA) (I) has been prepared by slow evaporation method in methanol, which was crystallized in monoclinic C2/c space group, Z = 8, and a = 28.431 (2) Å, b = 7.3098 (5) Å, c = 14.2622 (10) Å and β = 109.618 (3)°. The presence of unionized –COOH functional group in cocrystal I was identified both by spectral methods (1H and 13C NMR, FTIR) and X-ray diffraction structural analysis. The 2A4C6MP molecule interact with the carboxylic group of the respective 4MBA molecule thr

APA, Harvard, Vancouver, ISO, and other styles

10

Becker, Irwin. "Preparation of Pyrimidine Derivatives as Potential Medicinal Agents by the Reaction of 2-Amino-4-chloro-6-methylpyrimidine with Primary and Secondary Amines." ChemInform 37, no. 11 (2006). http://dx.doi.org/10.1002/chin.200611174.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!