Log in

Relevant bibliographies by topics / 2-Amino-4H-chromene / Journal articles

To see the other types of publications on this topic, follow the link: 2-Amino-4H-chromene.

Journal articles on the topic '2-Amino-4H-chromene'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic '2-Amino-4H-chromene.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Ju Liu, Ju Liu, Jian Tao Shi Jian Tao Shi, Xue Chen Hao Xue Chen Hao, Yu Tong Liu Yu Tong Liu, Shi Ding Shi Ding, and Yang Wang and Ye Chen Yang Wang and Ye Chen. "Synthesis of New Substituted 2-amino-4H-benzo[h]chromene-3-carbonitrile Derivatives." Journal of the chemical society of pakistan 41, no. 5 (2019): 888. http://dx.doi.org/10.52568/000795/jcsp/41.05.2019.

Full text

Abstract:

A series of novel substituted 2-amino-4H-benzo[h]chromene-3-carbonitrile derivatives was synthesised by condensation of different halogen derivatives with the hydroxy-group of 2-amino-8-hydroxy-4-styryl- 4H-benzo[h]chromene-3-carbonitrile and 2-amino-8-hydroxy-4- phenethyl-4H-benzo-[h]chromene-3-carbonitrile, which were prepared from cinnamaldehyde, malononitrile and naphthalene-1,6-diol through Knoevenagel condensation and cyclization reaction and then reduction with hydrogen in the presence of Pd/C at room temperature. Each intermediates and target compounds were obtained in good yields.

APA, Harvard, Vancouver, ISO, and other styles

2

Thanh, Nguyen D., Do S. Hai, Vu T. N. Bich, et al. "Using Sodium Hydride and Potassium Carbonate as Bases in Synthesis of Substituted 2-Amino-4-aryl-7-propargyloxy-4H-chromene-3-carbonitriles." Current Organic Synthesis 16, no. 3 (2019): 423–30. http://dx.doi.org/10.2174/1570179416666190104124652.

Full text

Abstract:

Aims and Objective: 1-Alkynes are the important precursors for the CuAAC click chemistry. The hybrid of 1,2,3-triazole ring to the chromene ring and sugar moiety could bring some remarkable biological properties. Propargyl derivatives are usually used in the click chemistry. This article reported the synthesis of 2-amino-4-aryl-7-propargyloxy-4-aryl-4H-chromene-3-carbonitriles using propargyl bromide as alkylation agent and the use of potassium carbonate and sodium hydride as bases in the conversion of 2-amino-4-aryl-7- hydroxy-4-aryl-4H-chromene-3-carbonitriles into corresponding propargyl et

APA, Harvard, Vancouver, ISO, and other styles

3

Xu, Da-Zhen, Cheng-Bin Li, and Yu-Wei Li. "An Efficient and Ecofriendly Three-Component Reaction for the Rapid Synthesis of 2-Amino-4H-chromenes Catalyzed by a DABCO-Based Ionic Liquid." Synthesis 50, no. 18 (2018): 3708–14. http://dx.doi.org/10.1055/s-0037-1610123.

Full text

Abstract:

An efficient, economical, and green strategy for the construction of biologically relevant 2-amino-4H-chromene scaffolds via a tandem Knoevenagel–Pinner cyclization–Michael reaction has been successfully developed. In the presence of DABCO-based ionic liquids, two different 2-amino-4H-chromene derivatives, 2-amino-4-(indol-3-yl)-4H-chromenes and 2-amino-4-(pyrazol-4-yl)-4H-chromenes, were prepared in good to excellent yields (81–97%) within short reaction times under mild conditions. All the products are purified by simple crystallization. The catalyst could be recycled for at least five times

APA, Harvard, Vancouver, ISO, and other styles

4

El-Maghraby, Awatef Mohamed. "Green Chemistry: New Synthesis of Substituted Chromenes and Benzochromenes via Three-Component Reaction Utilizing Rochelle Salt as Novel Green Catalyst." Organic Chemistry International 2014 (January 30, 2014): 1–6. http://dx.doi.org/10.1155/2014/715091.

Full text

Abstract:

Substituted 2-amino-4-aryl-7-hydroxy-4H-chromene-3-carbonitriles (6), 2-amino-4-aryl-4H-benzo[h]chromene-3-carbonitriles (7), and 3-amino-1-aryl-1H-benzo[f]chromenes-2-carbonitriles (8) were prepared, in good yields, via one-pot three-component reactions of aromatic aldehydes (1), malononitrile (2), and resorcinol (3) or α-naphthol (4) or β-naphthol (5) in refluxing ethanol or water in the presence of Rochelle salt as novel green heterogeneous and reusable catalyst.

APA, Harvard, Vancouver, ISO, and other styles

5

Mahesh S and Balaji G L. "PEG-SO3H promoted one pot grinding method for the synthesis of 2-amino-4H-chromene-3-carboxylates." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 5321–27. http://dx.doi.org/10.26452/ijrps.v11i4.3152.

Full text

Abstract:

There is a crucial medical need for the synthesis of 4H-chromene compounds via simple efficient methods. 4H-chromene compounds are stated to have a wide range of medicinal applications such as anti-bacterial, anti-cancer (EPC2407 and MX58151), antimalarial, antifungal, anti-rheumatic and anti-viral properties depending up on the substituents which is present on the heterocyclic compounds. Nowadays multi component protocols shows a better advantages such as better yield, less reaction time and no usage of different solvents for synthesis of biological important heterocyclic compounds over other

APA, Harvard, Vancouver, ISO, and other styles

6

Mohammed, Hamid Hashim. "Synthesis of fused cyclic chromene and alicyclic chromene derivatives from 2-amino-4-[4-(dimethylamino)phenyl]5-oxo-4H,5H-pyrano [3,2-c]chromene-3-carbonitrile." Al-Mustansiriyah Journal of Science 27, no. 5 (2017): 36. http://dx.doi.org/10.23851/mjs.v27i5.165.

Full text

Abstract:

Derivatives of fused cyclic chromene and alicyclic chromene were synthesized starting from 2-amino-4-[4-(dimethylamino)phenyl]5-oxo-4H,5H-pyrano [3,2-c]chromene-3-carbonitrile. The structures of the synthesized compounds were elucidated by spectral data : infrared spectra (FT-IR) and 1HNMR.

APA, Harvard, Vancouver, ISO, and other styles

7

Hiremath, Prashant B., and Kantharaju Kamanna. "A Microwave Accelerated Sustainable Approach for the Synthesis of 2-amino-4H-chromenes Catalysed by WEPPA: A Green Strategy." Current Microwave Chemistry 6, no. 1 (2019): 30–43. http://dx.doi.org/10.2174/2213335606666190820091029.

Full text

Abstract:

Background: The agricultural wastes as a source offer an excellent alternative to replace many toxic and environmentally hazardous catalysts, due to their least toxicity, ease of biodegradability, and ability to act as a greener catalytic medium. Some of the agro-waste based catalysts reported are BFE, WERSA, WEB, and WEPBA. 2-Amino-4H-chromene derivatives are promising biologically potent heterocyclic compounds, due to their medicinal applications such as antimicrobial, anti-inflammatory, antibacterial, antiviral, anticancer, antidiuretic, anticoagulant and antianaphylactic activities. The pr

APA, Harvard, Vancouver, ISO, and other styles

8

Al-Masoudi, Najim A., Hamid H. Mohammed, Aws M. Hamdy, et al. "Synthesis and anti-HIV Activity of New Fused Chromene Derivatives Derived from 2-Amino-4-(1-naphthyl)-5-oxo-4H,5H-pyrano[3,2- c]chromene-3-carbonitrile." Zeitschrift für Naturforschung B 68, no. 3 (2013): 229–38. http://dx.doi.org/10.5560/znb.2013-2297.

Full text

Abstract:

A new series of pyrano-chromene and pyrimido pyrano-chromene derivatives were synthesized starting from 2-amino-4-(1-naphthyl)-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile (6). The structures of the synthesized compounds were elucidated by spectral data. Compounds 6-11, 13-15 and 18 have been selected for an inhibitory activity screening against HIV-1 and HIV-2 in MT-4 cells.

APA, Harvard, Vancouver, ISO, and other styles

9

Dotsenko, V. V., E. A. Varzieva, D. S. Buriy, N. A. Aksenov, and I. V. Aksenova. "First Synthesis of 2-Amino-5-hydroxy-4H-chromene-3-carbonitriles from 4-(2-Pyridylazo)resorcinol." Russian Journal of General Chemistry 92, no. 11 (2022): 2254–58. http://dx.doi.org/10.1134/s1070363222110081.

Full text

Abstract:

Abstract 4-(2-Pyridylazo)resorcinol (PAR) sodium salt reacts with aromatic aldehydes and malononitrile in aqueous ethanol to form 2-amino-4-aryl-5-hydroxy-6-(2-pyridylazo)-4H-chromene-3-carbonitriles.

APA, Harvard, Vancouver, ISO, and other styles

10

Bardasov, Ivan N., Anastasiya U. Alekseeva, Oleg V. Ershov, and Dmitry A. Grishanov. "One-pot synthesis of 4-alkyl-2-amino-4H-chromene derivatives." Heterocyclic Communications 21, no. 3 (2015): 175–77. http://dx.doi.org/10.1515/hc-2015-0077.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Abbaspour-Gilandeh, Esmayeel, Mehraneh Aghaei-Hashjin, Asieh Yahyazadeh, and Hadi Salemi. "(CTA)3[SiW12]–Li+–MMT: a novel, efficient and simple nanocatalyst for facile and one-pot access to diverse and densely functionalized 2-amino-4H-chromene derivatives via an eco-friendly multicomponent reaction in water." RSC Advances 6, no. 60 (2016): 55444–62. http://dx.doi.org/10.1039/c6ra09818e.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Medishetti, Nagaraju, Ashok Kale, Jagadeesh Nanubolu, and Krishnaiah Atmakur. "Molecular-Iodine-Promoted Synthesis of Dihydrobenzofuran-3,3-dicarbonitriles through a Novel Rearrangement." Synlett 30, no. 03 (2019): 293–98. http://dx.doi.org/10.1055/s-0037-1611706.

Full text

Abstract:

The title compounds were synthesized from 5,5-dimethylcyclohexane-1,3-dione, benzaldehyde, and malononitrile promoted by molecular iodine in basic medium via 2-amino-7,7-dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile, by a novel protocol. The protocol involves a novel rearrangement in which the 4H-chromene fragment dissociates to a cyclopropane moiety and rearranges to the five-membered compound 6,6-dimethyl-4-oxo-2-phenyl-4,5,6,7-tetrahydrobenzofuran-3,3(2H)-dicarbonitrile. Simple reaction conditions, excellent yields, and high compatibility are the advantages of this

APA, Harvard, Vancouver, ISO, and other styles

13

Kumbhar, Arjun, Sanjay Jadhav, Rajendra Shejwal, Gajanan Rashinkar, and Rajshri Salunkhe. "Application of novel multi-cationic ionic liquids in microwave assisted 2-amino-4H-chromene synthesis." RSC Advances 6, no. 23 (2016): 19612–19. http://dx.doi.org/10.1039/c6ra01062h.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Dangolani, Soheila Khajeh, Farhad Panahi, Maryam Nourisefat, and Ali Khalafi-Nezhad. "4-Dialkylaminopyridine modified magnetic nanoparticles: as an efficient nano-organocatalyst for one-pot synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives in water." RSC Advances 6, no. 95 (2016): 92316–24. http://dx.doi.org/10.1039/c6ra18078g.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Ha Thanh, Nguyen, Hoang Thi Phuong, Le Nhat Thuy Giang, et al. "Multicomponent reaction for the synthesis of novel fluorinated 2-amino-4H-benzo[g]chromene-5,10-dione-3-carbonitriles." Vietnam Journal of Science and Technology 61, no. 6 (2023): 964–74. http://dx.doi.org/10.15625/2525-2518/17497.

Full text

Abstract:

Chromene is a significant class of heterocyclic compounds prossessing a simple structure as well as important biological activities. Many studies have been done to find new approaches for the preparation of chromene derivatives. Notably, the introduction of fluorine into heterocyclic molecules resulted in a significant improvement of their biological activities. In this study, a simple, straightforward, and highly efficient microwave-assisted three-component synthesis of novel 2-amino-4H-benzo[g]chromene-5,10-dione-3-carbonitrile derivatives bearing fluorine atoms has been developed using 1,4-

APA, Harvard, Vancouver, ISO, and other styles

16

Shenbagavalli, Kathiravan, Shiv Kumar Yadav, Periyasamy Ananthappan, Ellairaja Sundaram, Sarkaraisamy Ponmariappan, and Vairathevar Sivasamy Vasantha. "A simple and fast protocol for the synthesis of 2-amino-4-(4-formylphenyl)-4H-chromene-3-carbonitrile to develop an optical immunoassay for the quantification of botulinum neurotoxin type F." New Journal of Chemistry 44, no. 46 (2020): 20083–91. http://dx.doi.org/10.1039/d0nj04103c.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Ramireddy, Naresh, Santhi Abbaraju, Derong Ding, Hadi Arman, and John C. G. Zhao. "Organocatalyzed Enantioselective Synthesis of 2-Amino-4H-chromene Derivatives." Journal of Heterocyclic Chemistry 54, no. 1 (2016): 677–91. http://dx.doi.org/10.1002/jhet.2641.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Shinde, Sachin, Shashikant Damate, Smita Morbale, Megha Patil, and Suresh S. Patil. "Aegle marmelos in heterocyclization: greener, highly efficient, one-pot three-component protocol for the synthesis of highly functionalized 4H-benzochromenes and 4H-chromenes." RSC Advances 7, no. 12 (2017): 7315–28. http://dx.doi.org/10.1039/c6ra28779d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Paplal, Banoth, S. Nagaraju, Palakollu Veerabhadraiah, et al. "Recyclable Bi2WO6-nanoparticle mediated one-pot multicomponent reactions in aqueous medium at room temperature." RSC Adv. 4, no. 97 (2014): 54168–74. http://dx.doi.org/10.1039/c4ra07708c.

Full text

Abstract:

Room temperature multicomponent reactions (MCRs) are reported using Bi<sub>2</sub>O<sub>3</sub>, BiVO<sub>4</sub>, and Bi<sub>2</sub>WO<sub>6</sub> (nanoparticle) as heterogeneous catalysts. Among these, Bi<sub>2</sub>WO<sub>6</sub> (5 mol%) nanoparticles showed excellent reactivity for the synthesis of functionalized dihydropyridine, polyhydroquinoline, 4H-chromene and 2-amino-4H-benzo[b]pyran derivatives in aqueous medium.

APA, Harvard, Vancouver, ISO, and other styles

20

Abdallah, A. B., Adel M. Youins та Mohamed R. El-Kholany. "Selective separation of uranyl ions from some lanthanide elements using a promising β-enaminoester ligand by cloud point extraction". RSC Advances 12, № 14 (2022): 8520–29. http://dx.doi.org/10.1039/d2ra00274d.

Full text

Abstract:

For uranyl extraction, a distinctive chelating ligand, namely ethyl 2-amino-6-hydroxy-5-(4-methoxyphenyldiazenyl)-4-phenyl-4H-benzo[f]chromene-3-carboxylate, has been synthesized and characterized using FT-IR, NMR, and ESI-MS.

APA, Harvard, Vancouver, ISO, and other styles

21

Mohammadi, Reza, Somayeh Esmati, Mahdi Gholamhosseini-Nazari, and Reza Teimuri-Mofrad. "Synthesis and characterization of a novel Fe3O4@SiO2–BenzIm-Fc[Cl]/BiOCl nano-composite and its efficient catalytic activity in the ultrasound-assisted synthesis of diverse chromene analogs." New Journal of Chemistry 43, no. 1 (2019): 135–45. http://dx.doi.org/10.1039/c8nj04938f.

Full text

Abstract:

A new magnetic nano-catalyst bearing ionic liquid, ferrocene and BiOCl was synthesized and its catalytic activities were evaluated in the synthesis of a wide variety of 2-amino-3-cyano-4H-chromene derivatives (54 compounds) under ultrasound irradiation.

APA, Harvard, Vancouver, ISO, and other styles

22

Zhuang, Qiya, Daqing Shi, and Xiangshan Wang. "2-Amino-4-(2-chlorophenyl)-3-ethoxycarbonyl-4H-benzo[f]chromene." Acta Crystallographica Section E Structure Reports Online 59, no. 10 (2003): o1474—o1475. http://dx.doi.org/10.1107/s1600536803019779.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

SILAMBARASAN, SEKAR SILAMBU, and A. Jamal Abdul Nasser. "A BENIGN SYNTHESIS OF 2-AMINO-3-CYANO-4H-BENZOPYRANS VIA DOMINO REACTION." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 271–79. http://dx.doi.org/10.22270/jddt.v9i4-a.3417.

Full text

Abstract:

A green and operationally simple approach domino reaction has been developed for the synthesis of 2-amino-3-cyano- 4H-chromene derivatives from aromatic aldehydes, resorcinol and malononitrile in aqueous medium. This work represents the first example of catalyst free and organic solvents free multi-component reactions for the synthesis of pharmaceutically important chromene derivatives. The structures of the synthesized compounds were confirmed by 1H NMR, 13C NMR, IR, Mass and single crystal XRD. Keywords: Benzopyrans, malononitrile, Michael addition reaction, domino reaction, water medi

APA, Harvard, Vancouver, ISO, and other styles

24

Thanh, Nguyen Dinh, Do Son Hai, Pham Thi Thu Hien, et al. "Study on the Synthesis of Some (Un)Substituted 2-Amino-4-aryl-7-hydroxy-4H-chromene-3-carbonitriles in the Water Medium." Proceedings 9, no. 1 (2018): 67. http://dx.doi.org/10.3390/ecsoc-22-05665.

Full text

Abstract:

An efficient and simple synthesis of substituted 2-amino-4H-chromene-3-carbonitriles was developed by the one-pot and three-component reaction of a mixture of corresponding substituted benzaldehydes, resorcinol, and malononitrile in the presence of sodium carbonate solution as a catalyst at room temperature.

APA, Harvard, Vancouver, ISO, and other styles

25

Moustafa, Moustafa Sherief, Saleh Mohammed Al-Mousawi, Maghraby Ali Selim, Ahmed Mohamed Mosallam, and Mohamed Hilmy Elnagdi. "Organobase-catalyzed three-component reactions for the synthesis of 4H-2-aminopyrans, condensed pyrans and polysubstituted benzenes." Beilstein Journal of Organic Chemistry 10 (January 14, 2014): 141–49. http://dx.doi.org/10.3762/bjoc.10.11.

Full text

Abstract:

Novel routes for the preparation of 2-amino-4H-pyran-3-carbonitrile 9, amino-arylbenzoic acid ester derivatives 13a,b, 2-aminotetrahydro-4H-chromene-3-carbonitrile 18, 3-amino-4-cyanotetrahydronaphthalene-2-carboxylic acid ester 26 and 4-amino-3,5-dicyanophthalic acid ester derivatives 37a–c were developed. The synthetic methods utilize one-pot reactions of acetylene carboxylic acid esters, α,β-unsaturated nitriles and/or active methylenenitriles in the presence of L-proline or DABCO. Plausible mechanisms are suggested for the formation of the products. Finally, these compounds were used for t

APA, Harvard, Vancouver, ISO, and other styles

26

Guo, Cheng, and Xi-Feng Gu. "Ethyl 2-amino-4-(2-methoxyphenyl)-4H-benzo[h]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 61, no. 9 (2005): o3104—o3105. http://dx.doi.org/10.1107/s1600536805025018.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Guo, Cheng, Qing-Gang Tang, Chun-Xiang Ji, Dong-Mei Zhang, and Hong-Shun Sun. "Methyl 2-amino-4-(2-fluorophenyl)-4H-benzo[h]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 62, no. 10 (2006): o4750—o4751. http://dx.doi.org/10.1107/s1600536806035975.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Pore, Dattaprasad, and Mansing Mane. "Synthesis of 2-Amino-4-(3-amino-5-hydroxy-4H-pyrazol-4-ylidene)-4H-chromene-3-carbonitriles." Synlett 27, no. 11 (2016): 1720–24. http://dx.doi.org/10.1055/s-0035-1561952.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Sonsona, Isaac, Eugenia Marqués-López, and Raquel Herrera. "Enantioselective Organocatalyzed Synthesis of 2-Amino-3-cyano-4H-chromene Derivatives." Symmetry 7, no. 3 (2015): 1519–35. http://dx.doi.org/10.3390/sym7031519.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Gu, Xi-Feng, Cheng Guo, Dong-Mei Zhang, and Qing-Gang Tang. "2-Amino-4-(4-methoxyphenyl)-4H-benzo[h]chromene-3-carbonitrile." Acta Crystallographica Section E Structure Reports Online 61, no. 10 (2005): o3419—o3420. http://dx.doi.org/10.1107/s160053680502982x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Tang, Shi-Gui, Xi-Feng Gu, and Ping Wei. "Ethyl 2-amino-4-phenyl-4H-benzo[h]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 62, no. 1 (2005): o136—o137. http://dx.doi.org/10.1107/s1600536805040729.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Al-Dies, Al-Anood M., Abdel-Galil E. Amr, Ahmed M. El-Agrody, Tze Shyang Chia, and Hoong-Kun Fun. "2-Amino-4-(4-fluorophenyl)-6-methoxy-4H-benzo[h]chromene-3-carbonitrile." Acta Crystallographica Section E Structure Reports Online 68, no. 6 (2012): o1934—o1935. http://dx.doi.org/10.1107/s1600536812023021.

Full text

Abstract:

In the title molecule, C21H15FN2O2, the dihedral angle between the fluoro-substituted benzene ring and the mean plane of the 4H-benzo[h]chromene ring system [maximum deviation = 0.109 (2) Å] is 83.35 (7)°. The pyran ring adopts a slight sofa conformation with the tertiary C(H) atom forming the flap. The methoxy group is slightly twisted from the attached benzene ring of the 4H-benzo[h]chromene moiety [C—O—C—C = −4.3 (3)°]. In the crystal, molecules are linked by intermolecular N—H...N hydrogen bonds into infinite wave-like chains along the b axis. The crystal packing is further stabilized by π

APA, Harvard, Vancouver, ISO, and other styles

33

Atalla, Ahmed A., Adel M. Kamal El-Dean, and Abd El-Fattah A. Harb. "Synthesis of some new heterocyclic compounds containing chromene." Collection of Czechoslovak Chemical Communications 56, no. 4 (1991): 916–22. http://dx.doi.org/10.1135/cccc19910916.

Full text

Abstract:

2-amino-3-cyano-4H-phenyl-benzo[f]chromene (I) was reacted with formamide, acetic anhydride, and ethyl cyanoacetate to produce compounds (II-IV), respectively. Compound IV reacted with HCONH2, POCl3 and P2S5 to produce corresponding pyrimidobenzochromene (V), chloropyridobenzochromene (VI) and mercaptopyridobenzochromene (VII). Compound VII reacted with α-halocompounds to produce corresponding S-alkylated derivatives (VIIIa to VIIIc), and compound (VI) reacted with different amines to produce corresponding alkyl amino-, or aryl aminopyridobenzochromene (IXa-IXc) but in using hydrazine hydrate,

APA, Harvard, Vancouver, ISO, and other styles

34

Azarifar, Davood, Younes Abbasi, and Omolbanin Badalkhani. "Leucine: green and efficient catalyst for the synthesis of 4H-chromenes." JOURNAL OF ADVANCES IN CHEMISTRY 10, no. 9 (2017): 3197–202. http://dx.doi.org/10.24297/jac.v10i9.6168.

Full text

Abstract:

Leucine, a naturally occurring Î±-amino acid, has been found as an effective catalyst to effect the one-pot three-component condensation reaction between aromatic aldehydes, malononitrile and 5,5-dimethyl-1,3-cyclohexanedione (dimedone). Various 2-amino-4-aryl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile derivatives are conveniently prepared by these reactions in excellent yields. High yields, short reaction times, simple work-up, use of green and naturally occurring catalyst and solvent are the main merits of the present protocol.

APA, Harvard, Vancouver, ISO, and other styles

35

El-Agrody, Ahmed M., Mohamed A. Al-Omar, Abdel-Galil E. Amr, Tze Shyang Chia, and Hoong-Kun Fun. "Ethyl 2-amino-4-(4-fluorophenyl)-6-methoxy-4H-benzo[h]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 68, no. 6 (2012): o1803—o1804. http://dx.doi.org/10.1107/s1600536812021939.

Full text

Abstract:

In the title compound, C23H20FNO4, the fluoro-substituted benzene ring is approximately perpendicular to the mean plane of the 4H-benzo[h]chromene ring system [maximum deviation = 0.264 (1) Å], with a dihedral angle of 83.79 (6)°. The pyran ring adopts a flattened boat conformation. The methoxy group is slightly twisted from the attached benzene ring of the 4H-benzo[h]chromene moiety [C—O—C—C = −2.1 (2)°]. An intramolecular N—H...O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked by N—H...O and N—H...F hydrogen bonds into a layer parallel to the bc plane. The cr

APA, Harvard, Vancouver, ISO, and other styles

36

Guo, Cheng, and Xi-feng Gu. "Ethyl 2-amino-4-(4-methoxyphenyl)-4H-benzo[h]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 61, no. 9 (2005): o3101—o3103. http://dx.doi.org/10.1107/s1600536805025006.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Guo, Cheng, Xi-Feng Gu, Lian-Di Zhang, and Yan Li. "Ethyl 2-amino-4-(3-fluorophenyl)-4H-benzo[h]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 61, no. 7 (2005): o2125—o2127. http://dx.doi.org/10.1107/s1600536805018283.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Tang, Shi-Gui, Qing-Gang Tang, Wen-Yuan Wu, Cheng Guo, and Chun-Xiang Ji. "Methyl 2-amino-4-(3-nitrophenyl)-4H-benzo[h]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 62, no. 9 (2006): o4100—o4101. http://dx.doi.org/10.1107/s1600536806031412.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Tang, Qing-Gang, Chun-Xiang Ji, Jing Heng, Dong-Mei Zhang, and Cheng Guo. "Ethyl 2-amino-4-(4-fluorophenyl)-4H-benzo[h]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 62, no. 9 (2006): o4134—o4135. http://dx.doi.org/10.1107/s1600536806033733.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Shi, Daqing, Juxian Wang, Xiangshan Wang, Qiya Zhuang, and Kaibei Yu. "Ethyl 2-amino-4-(2,4-dichlorophenyl)-4H-benzo[f]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 59, no. 11 (2003): o1733—o1734. http://dx.doi.org/10.1107/s1600536803022852.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Shi, Daqing, Hui Wu, Xiangshan Wang, Qiya Zhuang, and Hongwen Hu. "Ethyl 2-amino-4-(4-methylphenyl)-4H-benzo[f]chromene-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 59, no. 9 (2003): o1263—o1264. http://dx.doi.org/10.1107/s1600536803017033.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Gao, Yu, Wen Yang, and Da-Ming Du. "Efficient organocatalytic asymmetric synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives." Tetrahedron: Asymmetry 23, no. 5 (2012): 339–44. http://dx.doi.org/10.1016/j.tetasy.2012.02.019.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Wang, Xiaoli. "2-Amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile." Acta Crystallographica Section E Structure Reports Online 67, no. 4 (2011): o832. http://dx.doi.org/10.1107/s1600536811008130.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Curini, Massimo, Ornelio Rosati, Maria Carla Marcotullio, et al. "Preparation of 2-Amino-4H-chromene Derivatives from Coumarins in Basic Media." European Journal of Organic Chemistry 2006, no. 3 (2006): 746–51. http://dx.doi.org/10.1002/ejoc.200500495.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Choura, Emna, Fares Elghali, Paul J. Bernard, et al. "Benzochromenopyrimidines: Synthesis, Antiproliferative Activity against Colorectal Cancer and Physicochemical Properties." Molecules 27, no. 22 (2022): 7878. http://dx.doi.org/10.3390/molecules27227878.

Full text

Abstract:

Ten new differently substituted 3-benzyl-5-aryl-3,5-dihydro-4H-benzo[6,7]chromeno[2,3-d]pyrimidin-4,6,11-triones 3 were synthesized by a simple and cost-efficient procedure in a one-pot, three-component reaction from readily available ethyl 2-amino-4-aryl-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carboxylates, benzylamine and triethyl orthoformate under solvent- and catalyst-free conditions. All the new compounds were screened for their antiproliferative activity against two colorectal-cancer-cell lines. The results showed that the compounds 3-benzyl-5-phenyl-3,5-dihydro-4H-benzo[6,7]chrom

APA, Harvard, Vancouver, ISO, and other styles

46

Mohamed, Shaaban K., Mehmet Akkurt, Muhammad N. Tahir, Antar A. Abdelhamid, and Mustafa R. Albayati. "2-Amino-4-(4-methylphenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile." Acta Crystallographica Section E Structure Reports Online 68, no. 8 (2012): o2315—o2316. http://dx.doi.org/10.1107/s1600536812029480.

Full text

Abstract:

The 4H-pyran ring of the title compound, C17H16N2O2, is nearly planar [maximum deviation = 0.077 (2) Å] and the cyclohexene ring adopts a flattened chair conformation [puckering parameters:QT= 0.435 (2) Å, θ = 122.0 (3)° and φ = 53.5 (3)°]. The 4H-pyran ring is almost perpendicular to the benzene ring [dihedral angle = 87.23 (8)°] and is almost coplanar with the mean plane of the cyclohexene ring [dihedral angle = 8.01 (8)°]. In the crystal, inversion-related molecules are linked by pairs of intermolecular N—H...N hydrogen bonds, forming inversion dimers withR22(12) ring motifs. These dimers a

APA, Harvard, Vancouver, ISO, and other styles

47

Koz, Gamze, Omer Koz, and Necdet Coskun. "Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes." Synthetic Communications 46, no. 10 (2016): 909–15. http://dx.doi.org/10.1080/00397911.2016.1177728.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Nesterov, Vladimir N., David J. Wiedenfeld, Svitlana V. Nesterova, and Mark A. Minton. "2-Amino-4-(1-naphthyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile and 2-amino-7,7-dimethyl-4-(1-naphthyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile." Acta Crystallographica Section C Crystal Structure Communications 60, no. 5 (2004): o334—o337. http://dx.doi.org/10.1107/s0108270104006924.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Mahdavi, M., A. Asadipour, S. Rajabalian, et al. "Synthesis andIn VitroCytotoxic Activity of 2-Amino-7-(dimethylamino)-4-[(trifluoromethyl)phenyl]-4H-chromenes." E-Journal of Chemistry 8, no. 2 (2011): 598–602. http://dx.doi.org/10.1155/2011/929673.

Full text

Abstract:

Three 2-amino-4-(trifluoromethylphenyl)-3-cyano-7-(dimethylamino) -4H-chromene derivatives were synthesized and their cytotoxic activities were determined against six human tumor cell lines using MTT assay. Condensation of 3-(dimethylamino)phenol, trifluoromethybenzaldehydes and malonitrile in ethanol containing piperidine afforded corresponding chromenes(4a-c). The structure of the synthesized compound was confirmed by1H NMR, IR and Mass spectral data. Among compounds tested, 3-trifluoromethyl analogue(3b)was the most active against all human tumor cell lines (IC50=12-45 nM).

APA, Harvard, Vancouver, ISO, and other styles

50

S., Sheik Mansoor, and Ghashang M. "An appropriate one-pot synthesis of dihydropyrano[2,3-c]pyrazoles and 2-amino-3-cyano-7-hydroxy-4-substituted-4H-chromene derivatives using thiourea dioxide as an efficient and reusable organocatalyst." Journal Of Indian Chemical Society Vol. 92, Sep 2015 (2015): 1449–59. https://doi.org/10.5281/zenodo.5701932.

Full text

Abstract:

Research Department of Chemistry, Bioactive Organic Molecule Synthetic Unit, C. Abdul Hakeem College, Melvisharam-632 509, Tamilnadu, India E-mail : smansoors2000@yahoo.co.in Faculty of Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Esfahan, Iran Manuscript received online 13 November 2014, revised 02 February 2015, accepted 04 February 2015 Thiourea dioxide (<strong>TUD</strong>) was used as a recyclable organocatalyst for the synthesis of 6-amino-4-aryl-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles and 2-amino-3-cyano-7-hydroxy-4-substituted-<em>4H</em>-chromen

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!