Academic literature on the topic '2-amino-propanamide'

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Journal articles on the topic "2-amino-propanamide"

1

Macháček, Vladimír, Makky M. M. Hassanien, Vojeslav Štěrba, and Antonín Lyčka. "Formation of the Meisenheimer spiro adduct of N-(2,4,6-trinitrophenyl)alanine methylamide and its rearrangement to 2-amino-N-methyl-N-(2,4,6-trinitrophenyl)propanamide." Collection of Czechoslovak Chemical Communications 51, no. 9 (1986): 1972–85. http://dx.doi.org/10.1135/cccc19861972.

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N-(2,4,6-trinitrophenyl)alanine methylamide (I) undergoes base-catalyzed cyclization in methanol to give the spiro adduct II. In aniline-anilinium chloride buffers, the spiro adduct is protonated at the oxygen atom of 2-nitro group to give the neutral compound III. In 4-bromoaniline buffers or by action of methanolic hydrogen chloride, the compound III is opened to E and Z isomers of 2-amino-N-methyl-N-(2,4,6-trinitrophenyl)propanamide hydrochloride (IV). The rate-limiting step of cyclization of compound Z-IV to compound III consists in the isomerization Z-IV → E-IV. At higher pH values (aceta
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2

Manolov, Stanimir, Iliyan Ivanov, Dimitar Bojilov, and Paraskev Nedialkov. "2-(2-Fluoro-[1,1′-biphenyl]-4-yl)-N-(4-methyl-2-oxo-2H-chromen-7-yl)propanamide." Molbank 2023, no. 3 (2023): M1682. http://dx.doi.org/10.3390/m1682.

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Herein, we report the synthesis of 2-(2-fluoro-[1,1′-biphenyl]-4-yl)-N-(4-methyl-2-oxo-2H-chromen-7-yl)propanamide in the reaction between 7-amino-4-methyl-2H-chromen-2-one and (±)-flurbiprofen. The newly-obtained bio-functional hybrid compound was fully characterized via 1H, 13C NMR, UV, and mass spectral data.
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3

Sravya, Gundala, Ummadi Nagarjuna, Venkatapuram Padmavathi, Galla Rajitha, Sakuri Chandi priya, and Adivireddy Padmaja. "Synthesis, Antioxidant and Anti-inflammatory Activities of 5-((styrylsulfonyl) methyl)-1,3,4-Oxadiazol / Thiadiazol-2-amine Derivatives." Letters in Drug Design & Discovery 16, no. 11 (2019): 1233–47. http://dx.doi.org/10.2174/1570180816666181102114529.

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Background: A new class of 5-(styrylsulfonylmethyl)-1,3,4-oxadiazol-2-amine and 5- (styrylsulfonylmethyl)-1,3,4-thiadiazol-2-amine derivatives were prepared by derivatization of amino function. Methods: All the synthesized compounds were tested for antioxidant and anti-inflammatory activities. Results: The 2-amino-3-chloro-N-(5-(4-methylstyrylsulfonylmethyl)-1,3,4-oxadiazol-2-yl)-propanamide (12b) and 3-chloro-N-(5-(4-methylstyrylsulfonylmethyl)-1,3,4-oxadiazol-2-yl)-butanamide (14b) displayed significant antioxidant activity, greater than the standard Ascorbic acid. Conclusion: Moreover, 12b
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4

Zareva, Sonya. "Solid-state linear-dichroic infrared (IR-LD) spectroscopic and theoretical characterization of 2-[(2-ethoxy-3,4-dioxocyclobut-1-en-yl)amino]propanamide." Open Chemistry 4, no. 4 (2006): 695–707. http://dx.doi.org/10.2478/s11532-006-0034-0.

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Abstract2-[(2-Ethoxy-3,4-dioxocyclobut-1-en-yl)amino]propanamide (N-alaninamidoamide of squaric acid ethyl ester) has been characterized structurally and spectroscopically by ab initio calculations and IR-LD spectroscopy of oriented crystals suspended in a nematic liquid crystal. The results are compared with single crystal X-ray structures illustrating the possibilities of this experimental approach to obtaining structural information as well as assigning IR bands.
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5

Yu-hua, Zhang, Duan Chun-sheng, Fu Hui, et al. "Theoretical study on the influence of formamide on the optical rotation of 2-amino-propanamide." Journal of Indian Chemical Society Vol. 88, Apr 2011 (2011): 525–30. https://doi.org/10.5281/zenodo.5766678.

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College of Chemistry &amp; Chemical Engineering, China University of Petroleum, Shangdong, Qingdao 266555, People&#39;s Republic of China <em>E-mail</em> : zhengyu@mail.qfnu.edu.cn, niceuu@163.com Department of Chemistry, Qufu Normal University, Shandong, Qufu 273165, People&#39;s Republic of China lnstitute of Vocational and Adult Edttcation of Qufu Normal University, Shandong 273165, People&#39;s Republic of China <em>Manuscript received 28 May 2010, accepted 16 August 2010</em> Five stationary points of formamlde-2-amino propionamide complexes have been optimized at the B3LYP/6- 311++G (2d,
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6

Rima, Ghassoub, Jacques Satgé, Rodolphe Dagiral, et al. "Synthesis and Radioprotective Activity of New Organosilicon and Germanium Compounds." Metal-Based Drugs 5, no. 3 (1998): 139–46. http://dx.doi.org/10.1155/mbd.1998.139.

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Silathiazolidine and metalladithioacetals (M = Si, Ge) have been prepared by the interaction of dialkyldichloro- or bis(diethylamino)dialkylsilanes and -germanes with 3-[N-(2- thioethyl)]amino-propanamide (WR-2529) and [1-thioethyl-2-(1-naphtylmethyl)]-2- imidazoline. The study of these compounds in the field of chemical radioprotection has shown a notable decrease in the toxicity and a rather large increase in the radioprotective activity of these new derivatives in comparison with the starting organic compounds.
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7

Tüzün, Işıl, Ayten Y. Karataş, Özge Şeşenoğlu, Ayhan S. Demir, and Gülay Özcengiz. "2-Amino-N-(2-furylmethyl)propanamide as a novel alanylglycine equivalent synthesized by bacilysin synthetase." Enzyme and Microbial Technology 33, no. 5 (2003): 725–28. http://dx.doi.org/10.1016/s0141-0229(03)00209-6.

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8

Sedlák, Miloš, Jiří Hanusek, Radim Bína, Jaromír Kaválek, and Vladimír Macháček. "Kinetics and Mechanism of the Formation and Decomposition of Imidazolin-4-ones from 2-(N-Benzoylamino)alkanamides in Aqueous Medium." Collection of Czechoslovak Chemical Communications 64, no. 10 (1999): 1629–40. http://dx.doi.org/10.1135/cccc19991629.

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The cyclization reactions of substituted 2-(N-benzoyl-N-methyl)aminoalkanamides 1a-1g have been studied in aqueous medium. The Hammett reaction constant is ρ = 1.4 for the cyclization reactions of compounds 1a-1e in sodium hydroxide solutions. 2-[N-Methyl- N-(4-nitrobenzoyl)amino]-2-(4-nitrophenyl)propanamide (1g) is cyclized to imidazolinone 2g in aqueous amine buffers of pH 9-11.5; the reaction is subject to specific base catalysis in these media, and the rate-limiting step is the formation of a tetrahedral intermediate. In sodium hydroxide solution, the primary cyclization product is hydrol
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9

Jonuškienė, Ilona, Rima Stankevičienė, Kristina Kantminienė, and Ingrida Tumosienė. "The Influence of Phytohormones on Antioxidative and Antibacterial Activities in Callus Cultures of Hypericum perforatum L." Agriculture 13, no. 8 (2023): 1543. http://dx.doi.org/10.3390/agriculture13081543.

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Natural extracts of Hypericum perforatum L. are widely used in the pharmaceutical industry due to their antiviral, antioxidant, antibacterial, antidiabetic, and antidepressant activities. Plant biotechnological methods are gaining more attention as efficient and biosustainable approaches for the production of high value compounds by using plant callus cultures in vitro. The aim of this research was to evaluate the influence of phytohormones on the formation of Hypericum perforatum L. callus culture, to explore antioxidant and antibacterial activities, and to determine the amounts of phytochemi
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10

Tumosienė, Ingrida, Kristina Kantminienė, Arnas Klevinskas, Vilma Petrikaitė, Ilona Jonuškienė, and Vytautas Mickevičius. "Antioxidant and Anticancer Activity of Novel Derivatives of 3-[(4-Methoxyphenyl)amino]propanehydrazide." Molecules 25, no. 13 (2020): 2980. http://dx.doi.org/10.3390/molecules25132980.

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Series of novel 3-[(4-methoxyphenyl)amino]propanehydrazide derivatives bearing semicarbazide, thiosemicarbazide, thiadiazole, triazolone, triazolethione, thiophenyltriazole, furan, thiophene, naphthalene, pyrrole, isoindoline-1,3-dione, oxindole, etc. moieties were synthesized and their molecular structures were confirmed by IR, 1H-, 13C-NMR spectroscopy and mass spectrometry data. The antioxidant activity of the synthesized compounds was screened by DPPH radical scavenging method. The antioxidant activity of N-(1,3-dioxoisoindolin-2-yl)-3-((4-methoxyphenyl)amino)propanamide and 3-((4-methoxyp
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