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Relevant bibliographies by topics / 2-Amino substituted benzothiazole

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Academic literature on the topic '2-Amino substituted benzothiazole'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "2-Amino substituted benzothiazole"

1

Srivastav, Manish, MD Salahuddin, and S. M. Shantakumar. "Synthesis and Anti-inflammatory Activity of Some Novel 3-(6-Substituted-1, 3-benzothiazole-2-yl)-2-[{(4-substituted phenyl) amino} methyl] quinazolines-4 (3H)-ones." E-Journal of Chemistry 6, no. 4 (2009): 1055–62. http://dx.doi.org/10.1155/2009/507052.

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A series of novel 3-(6-substituted-1, 3-benzothiazole-2-yl)-2-[{(4-substituted phenyl) amino} methyl] quinazolines-4(3H)-ones were synthesized by treating 2-(chloromethyl)-3-(6-substituted-1, 3-benzothiazole-2-yl) quinazoline-4-(3H)-one (IIa-d) with various substituted amine. The compounds (IIa-d) prepared by treating 2-[(chloroacetyl) amino] benzoic acid with different 2-amino-6-substituted benzothiazole. Elemental analysis, IR,1HNMR and mass spectral data confirmed the structure of the newly synthesized compounds. Synthesized quinazolines-4-one derivative were investigated for their anti-inf

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2

Gangadhar, S. Bhopalkar. "Synthesis and Characterization of 3-Cyano-6,9-dimethyl-4-oxo-2-methylthio- 4H-Pyrimido[2,1-b][1,3] Benzothiazole and its 2-Substituted derivatives." Chemistry Research Journal 6, no. 4 (2021): 132–35. https://doi.org/10.5281/zenodo.11758088.

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<strong>Abstract </strong>A compound 3-cyano-6, 9-dimethyl- 4-oxo 2-methylthio-4H-Pyrimido[2,1-<em>b</em>][1,3] benzothiazole 3 has been prepared by the reaction of<strong> </strong>2-amino- 4,7- dimethyl [1, 3] benzothiazole 1<strong> </strong>with Ethyl -2-cyano-3,3’-bis-methylthio acrylate 2<strong> </strong>in presence of anhydrous K<sub>2</sub>CO<sub>3</sub> in DMF. The compound pyrimido benzothiazole 3 has methylthio functional group at 2- position which was substituted by using selected nucleophiles like substituted phenols, anilines, heteryl amine and active methylene compounds t

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3

Mistry, K. M., and K. R. Desai. "Synthesis of Novel Heterocyclic 4-Thiazolidinone Derivatives and their Antibacterial Activity." E-Journal of Chemistry 1, no. 4 (2004): 189–93. http://dx.doi.org/10.1155/2004/590439.

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4-Thiazolidinones have been prepared by the reaction of various substituted Schiff bases 3 with Thioglycolic acid and Thiolactic acid. The intermediate Schiff bases 3 were synthesized by the condensation of various substituted 2-amino benzothiazole 1 with 1-(4'-methyl Phenyl)-3-methyl-5-pyrazolone 2. The starting compound substituted 2-amino benzothiazoles were prepared from various substituted amines via substituted phenyl thiourea. The structures of the compounds have been confirmed by elemental analysis and spectral analysis. The antibacterial activity of the compounds has also been screene

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4

Schroeder, Zachary W., L. K. Hiscock, and Louise Nicole Dawe. "Copper(II)- and gold(III)-mediated cyclization of a thiourea to a substituted 2-aminobenzothiazole." Acta Crystallographica Section C Structural Chemistry 73, no. 11 (2017): 905–10. http://dx.doi.org/10.1107/s205322961701381x.

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Benzothiazole derivatives are a class of privileged molecules due to their biological activity and pharmaceutical applications. One route to these molecules is via intramolecular cyclization of thioureas to form substituted 2-aminobenzothiazoles, but this often requires harsh conditions or employs expensive metal catalysts. Herein, the copper(II)- and gold(III)-mediated cyclizations of thioureas to substituted 2-aminobenzothiazoles are reported. The single-crystal X-ray structures of the thiourea N-(3-methoxyphenyl)-N′-(pyridin-2-yl)thiourea, C13H13N3OS, and the intermediate metal complexes aq

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5

Purvesh, J. Shah. "Preparation, Characterization and Biological Screening of Novel Imidazoles." Journal of Progressive Research in Chemistry 2, no. 1 (2015): 54–60. https://doi.org/10.5281/zenodo.3970044.

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The 4-benzylidene-2-(4-methoxyphenyl)oxazol-5(4H)-one (B) has been prepared from cyclo condensation reaction between hippuric acid (A) with p-anisaldehyde. A series of 4-benzylidene-1-(substitued-2- benzothiazolyl)-2-(4-methoxyphenyl)-1H-imidazol-5(4H)-one (D1-6) have been synthesized from 2-amino substituted benzothiazole (C1-6) by condensation reaction with 4-benzylidene-2-(4-methoxyphenyl) oxazol-5(4H)-one (B). The synthesized compounds were characterized by IR, 1H-NMR, 13C-NMR and Mass spectral data. All the compounds were screened for their antibacterial and antifungal activities.

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6

N., B. Patel, and N. Agravat S. "Synthesis, characterization and biological screening of some new pyridine derivatives." Journal of Indian Chemical Society Vol. 84, Aug 2007 (2007): 785–91. https://doi.org/10.5281/zenodo.5824938.

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Department of Chemistry, Veer Narmad South Gujarat University, Surat-395 007, Gujarat, India <em>E-mail</em>: drnavin @satyam.net.in; snagravat@yahoo.co.in <em>Manuscript received 18 August 2006, revised 26 March 2007, accepted 13 June 2007</em> 2-Amino substituted benzothiazole 2<sub>1_12</sub> and<em> p</em>-acetamidobenzenesulfonyl chloride 1 were used to prepare <em>N"</em>-(<em>p</em>anilinosulfonamido) substitutedbenzothiazole 4<sub>1_12</sub> using mixture of pyridine and acetic anhydride which formed (<em>N</em>-acetyl pyridinium) an cleetrophilic complex which facilitated condens

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7

Sathe, B. S., E. Jaychandran, G. M. Sreenivasa, and V. A. Jagtap. "Antimycobacterial Activity of Some Synthesized Fluorinated Benzothiazolo Imidazole Compounds." E-Journal of Chemistry 8, no. 2 (2011): 830–34. http://dx.doi.org/10.1155/2011/581429.

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4-Fluoro-3-chloroanilline treated with potassium thiocyanate in presence of glacial acetic acid and bromine was converted into 2-amino-6-fluoro-7-chlorobenzothiazole, resulting into 2-amino benzothiazole. The synthesized compound in presence of 2-phenyl-4-benzylidine-5-oxazolinone refluxed in pyridine to obtain 2-(2-phenyl-4-benzylidenyl-5-oxo-imidazolin-1-yl amino)-6-fluoro-7-substituted(1,3)benzothiazoles. The above said compound was treated withortho, metaandpara nitroanillines, ortho, meta, parachloroanillines, morpholino, piperazine, diphenylamine in the presence of DMF to obtain differen

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8

Journal, Baghdad Science. "Synthesis , characterization and biological activity study of N-substituted sulfonamido maleimides substituted with different heterocycles." Baghdad Science Journal 7, no. 1 (2010): 641–53. http://dx.doi.org/10.21123/bsj.7.1.641-653.

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Eighteen new cyclic imides (maleimides) conncted to benzothiazole moiety through sulfonamide group were synthesized via multistep synthesis.The first step involved preparation of two maleamic acids N-phenylmaleamic acid and N-benzylmaleamic acid via reaction of maleic anhydride with aniline or benzyl amine.Dehydration of the prepared amic acids by treatment with acetic anhydride and anhydrous sodium acetate in the second step afforded N-phenylmaleimide and N- benzyl maleimide which in turn were treated with chlorosulfonic acid in the third step to afford 4-(N-maleimidyl) phenyl sulfonyl chlori

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9

Niharika, P., J. Risy Namratha, N. Sunitha, and S. Manohar Babu. "Synthesis and evaluation of 6-Fluoro benzothiazole substituted quinazolinones." Current Trends in Pharmacy and Pharmaceutical Chemistry 4, no. 1 (2022): 35–40. http://dx.doi.org/10.18231/j.ctppc.2022.007.

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The present work was hypothesized to synthesize Benzothiazole substituted diethyl amino Quinazolinone derivatives and evaluate their antimicrobial activity. Quinazolinones were synthesized from condensation of 2-amino benzothiazole, anthranilic acid and acetic anhydride further followed by condensation with formaldehyde and diethyl amine. Antimicrobial activity was evaluated by agar disc diffusion using organisms and anti-inflammatory and antioxidant activies were studied using albumin denaturation and hydrogen peroxide radical scavenging methods. The structures of the synthesized Quinazolinon

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10

Gangadhar, S. Bhopalkar. "Synthesis and in-vitro Anticancer Activity of 3 -Cyano- 9, 12-Dimethyl -4, 14-Diimino- 2-Methylthio- Pyrimido[2,3-b] Pyrazolo[3,4-e] Pyrimido[2,3-b][1,3] Benzothiazole and its 2-Substituted Derivatives." Chemistry Research Journal 8, no. 4 (2023): 13–19. https://doi.org/10.5281/zenodo.11352251.

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<strong>Abstract </strong> A new heterocyclic compound 3 -Cyano- 9, 12-dimethyl -4, 14-diimino- 2-methylthio- pyrimido[2,3<em>-b</em>] pyrazolo[3,4<em>-e</em>] pyrimido[2,3<em>-b</em>][1,3] benzothiazole 3 has been synthesised by the reaction of 3-amino- 4-imino- 6, 9-dimethyl- pyrazolo-[3, 4<em>-e</em>] pyrimido [2, 3<em>-b</em>] [1, 3] benzothiazole 2  with bis - methylthio methylene malononitrile  in presence of anhydrous K<sub>2</sub>CO<sub>3</sub> in DMF. Compound 3 has thiomethyl functionality at 2- position which was substituted by using selected nucleophiles like substituted

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Conference papers on the topic "2-Amino substituted benzothiazole"

1

Al-Joboury, Wissam Mohammed, Khalid Abdulaziz Al-Badrany, and Nabeel Jamal Asli. "N-alkylation of substituted 2-amino benzothiazoles by 1,4-bis (bromo methyl) benzene on mixed oxides at room temperature and study their biological activity." In 1ST SAMARRA INTERNATIONAL CONFERENCE FOR PURE AND APPLIED SCIENCES (SICPS2021): SICPS2021. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0123463.

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