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Journal articles on the topic '2-amino'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Elizondo García, Mariana, Sylvain Bernès, Nancy Pérez Rodríguez, and Perla Elizondo Martínez. "Tris{2-[(2-aminobenzylidene)amino]ethyl}amine." Acta Crystallographica Section E Structure Reports Online 66, no. 12 (2010): o3054—o3055. http://dx.doi.org/10.1107/s1600536810043783.

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2

Yin, Weiyan, Zhi Wang, Ying Liang, and Zi-Wen Yang. "(E)-(2-Chlorobenzylidene)amino 2-amino-4-chlorobenzoate." Acta Crystallographica Section E Structure Reports Online 68, no. 3 (2012): o770. http://dx.doi.org/10.1107/s1600536812003844.

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3

Zaki Dawood, Nagham M., Zainab Faiyq Saeed, and Banan Borhan Saeed. "SYNTHESIS OF ACETYLENIC AMINO DERIVATIVES OF 2-(2-((2,6- DICHLOROPHENYL)AMINO)PHENYL)ACETIC ACID." Chemical Problems 22, no. 3 (2024): 369–81. http://dx.doi.org/10.32737/2221-8688-2024-3-369-381.

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After reviewing a number of researches that demonstrate the effectiveness of a number of compounds containing the acetylenic amine group as antimicrobials and antiproliferative activity, our goal is to prepare new acetylenic amine derivatives from the compound 2-(2-((2,6- dichlorophenyl)amino)phenyl)acetic acid using the Mannich reaction by the react salt of a carboxylic acid with propargyl bromide to produce the compound (prop-2-yn-1-yl 2-(2-((2,6- dichlorophenyl)amino)phenyl)acetate) (1), which was refluxed with a number of secondary amines and formaldehyde in presence of the copper chloride

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4

Moroz, Yurii S., Michael K. Takase, Peter Müller, and Elena V. Rybak-Akimova. "Tris{2-[(2,6-dimethylphenyl)amino]ethyl}amine." Acta Crystallographica Section E Structure Reports Online 67, no. 12 (2011): o3421. http://dx.doi.org/10.1107/s1600536811049397.

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5

IMAI, Tokiko, Yoshihiro YOKOYAMA, Akiko SEKINE, Hidehiro UEKUSA, and Yuji OHASHI. "Structures of 2-Amino-2-deoxyascorbic acid and 2-Amino-2-deoxyerythorbic acid." Analytical Sciences: X-ray Structure Analysis Online 19 (2003): x65—x66. http://dx.doi.org/10.2116/analscix.19.x65.

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6

Aazam, Elham S., and Orhan Büyükgüngör. "2-Amino-3-[(E)-(2-hydroxy-3-methylbenzylidene)amino]but-2-enedinitrile." Acta Crystallographica Section E Structure Reports Online 68, no. 5 (2012): o1406. http://dx.doi.org/10.1107/s1600536812015243.

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7

Jin, Zhi-Min, Bin Tu, Lin He, Mao-Lin Hu, and Jian-Wei Zou. "2-Amino-5-methylpyridinium (2-amino-5-methylpyridine)trichlorozincate(II)." Acta Crystallographica Section C Crystal Structure Communications 61, no. 4 (2005): m197—m199. http://dx.doi.org/10.1107/s0108270105006694.

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8

Gong, Jiang, Gang Chen, Shi-Feng Ni, Yong-Yao Zhang, and Hai-Bin Wang. "2-Amino-3-methylpyridinium 2-amino-5-methylpyridinium sulfate monohydrate." Acta Crystallographica Section E Structure Reports Online 65, no. 12 (2009): o3183. http://dx.doi.org/10.1107/s1600536809049241.

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9

Aslam, M., I. Anis, N. Afza, M. T. Hussain, and S. Yousuf. "2-[(2-Methoxybenzylidene)amino]phenol." Acta Crystallographica Section E Structure Reports Online 68, no. 5 (2012): o1447. http://dx.doi.org/10.1107/s1600536812016224.

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10

Sapayev, F. A., R. Ya Okmanov, T. S. Kholikov, Kh S. Tadjimukhamedov, and B. Tashkhodjaev. "Crystal structures of 2-amino-2-oxoethyl 4-bromobenzoate, 2-amino-2-oxoethyl 4-nitrobenzoate and 2-amino-2-oxoethyl 4-aminobenzoate monohydrate." Acta Crystallographica Section E Crystallographic Communications 76, no. 12 (2020): 1805–9. http://dx.doi.org/10.1107/s2056989020014371.

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The title molecules were synthesized by the reaction of 4-substituted sodium benzoates with chloroacetic acid amide in the presence of dimethylformamide. The yields of 2-amino-2-oxoethyl 4-bromobenzoate, C9H8BrNO3, I, 2-amino-2-oxoethyl 4-nitrobenzoate, C9H8N2O5, II, and 2-amino-2-oxoethyl 4-aminobenzoate monohydrate, C9H10N2O3·H2O, III, are 86, 78 and 88%, respectively. The low yield of II is explained by the reduced reactivity of the molecule in a nucleophilic exchange reaction because of the negative induction and negative mesomeric effects of the nitro group on the benzene ring. Single cry

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11

M., B. Deshmukh, S. Jagtap S., A. Deshmukh S., Jadhav S.D., and V. Anbhule P. "Synthesis of amino acid derivatives of 2-mercaptobenzothiazole." Journal of Indian Chemical Society Vol. 85, Mar 2008 (2008): 290–92. https://doi.org/10.5281/zenodo.5814139.

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Department of Chemistry, Shivaji University, Kolhapur-416 004, Maharashtra, India <em>E-mail :</em> m_deshmukh1 @rediffmail.com <em>Manuscript received 18 August 2006, revised 7 May 2007. accepted 26 November 2007</em> The reaction of ethyl benzothiazole-2-yl-thioacetate and methyl benzothiazole-2-yl-thiopropionate with various amino acids in presence of alkali at 0-5 °C to form peptide has been described.

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12

Jasinski, Jerry P., Ray J. Butcher, Q. N. M. Hakim Al-Arique, H. S. Yathirajan, and B. Narayana. "N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine." Acta Crystallographica Section E Structure Reports Online 66, no. 2 (2010): o349. http://dx.doi.org/10.1107/s1600536810000899.

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13

Rohde Jr, Laurence N., Matthias Zeller, and John A. Jackson. "Crystal structures of chiral 2-[bis(2-chloroethyl)amino]-1,3,2-oxazaphospholidin-2-one derivatives for the absolute configuration at phosphorus." Acta Crystallographica Section E Crystallographic Communications 74, no. 9 (2018): 1330–35. http://dx.doi.org/10.1107/s2056989018011349.

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`Nitrogen mustard' bis(2-chloroethyl)amine derivatives (2R,4S,5R)- and (2S,4S,5R)-2-[bis(2-chloroethyl)amino]-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidin-2-one (2a and 2b, respectively), C14H21Cl2N2O2P, and (2R,4R)- and (2S,4R)-2-[bis(2-chloroethyl)amino]-4-isobutyl-1,3,2-oxazaphospholidin-2-one (3a and 3b, respectively), C10H21Cl2N2O2P, were synthesized as a mixture of diastereomers through a 1:1 reaction of enantiomerically pure chiral amino alcohols with bis(2-chloroethyl)phosphoramidic dichloride. Flash column chromatography yielded diastereomerically pure products, as supported by 31P N

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14

Remko, Milan, O. A. Walsh, and W. G. Richards. "Ab initio and DFT study of molecular structure and tautomerism of 2-amino-2-imidazoline, 2-amino-2-oxazoline and 2-amino-2-thiazoline." Chemical Physics Letters 336, no. 1-2 (2001): 156–62. http://dx.doi.org/10.1016/s0009-2614(01)00104-x.

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15

Hanif, Muhammad, Ezzat Khan, Muhammad Khalid, Muhammad Nawaz Tahir, Sara Figueirêdo de Alcântara Morais, and Ataualpa Albert Carmo Braga. "2-Amino-3-methylpyridinium, 2-amino-4-methylbenzothiazolium and 2-amino-5-chloropyridinium salts. Experimental and theoretical findings." Journal of Molecular Structure 1222 (December 2020): 128914. http://dx.doi.org/10.1016/j.molstruc.2020.128914.

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16

Ren, Qing-Yun, Hong-Wu He, Chuan-Fei Jin, and Yu-Cheng Gu. "Ethyl 4-amino-5-cyano-6-[(2-hydroxyethyl)amino]-2-methylnicotinate." Acta Crystallographica Section E Structure Reports Online 63, no. 10 (2007): o4015. http://dx.doi.org/10.1107/s1600536807043383.

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17

Alexander, Petr, Antonín Holý, Miloš Buděšínský, and Milena Masojídková. "Synthesis of Acyclic Nucleotide Analogues Derived from N3-Substituted Isoguanine." Collection of Czechoslovak Chemical Communications 65, no. 11 (2000): 1713–25. http://dx.doi.org/10.1135/cccc20001713.

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Reaction of 9-benzyl-6-{[(dimethylamino)methylidene]amino}purin-2(3H)-one (7) with ethylene carbonate gave a mixture of 9-benzyl-2-(2-hydroxyethoxy)purin-6-amine (10) and 2-amino-9-benzyl-3-(2-hydroxyethyl)purin-2(3H)-one (11). This mixture reacted with diisopropyl (tosyloxymethyl)phosphonate in the presence of NaH followed by catalytic hydrogenation and bromotrimethylsilane treatment to afford isomeric 6-amino-3-[2-(phosphonomethoxy)ethyl]purin-2(3H)-one (3) and 2-[2-(phosphonomethoxy)ethoxy]purin- 6-amine (15). Similar treatment of compound7with tritylglycidol gave two isomeric 2-hydroxy-3-(

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18

Hughes, Robert, and Rolf H. Prager. "Potential GABAB Receptor Antagonists. VIII. The Synthesis of 3-Amino-N-aryl-2-hydroxy- propane-1-sulfonamides and Analogues of Baclofen Containing Nitro Groups." Australian Journal of Chemistry 50, no. 1 (1997): 19. http://dx.doi.org/10.1071/c96149.

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3-Amino-N-aryl-2-hydroxypropane-1-sulfonamides were synthesized by the reaction of the corresponding epoxy sulfonamide with sodium azide, followed by reduction to the corresponding amine. The synthesis of 3-nitropropan-1-amine and two 2-thienyl derivatives is also reported. 3-Amino-2-hydroxy-N-(4-nitrophenyl)propane-1-sulfonamide and 3-nitropropan-1-amine were found to be specific antagonists of GABA at the GABAB receptor. Substitution of the amino group by alkyl or aryl groups reduced the activity.

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19

Prakash, Thazha P., Andrew M. Kawasaki, Elena A. Lesnik, Stephen R. Owens, and Muthiah Manoharan. "2‘-O-[2-(Amino)-2-oxoethyl] Oligonucleotides." Organic Letters 5, no. 4 (2003): 403–6. http://dx.doi.org/10.1021/ol027131k.

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20

Biermann, Manfred, Kenneth I. Hardcastle, Nikolai V. Moskalev, and Peter A. Crooks. "(S)-2-Amino-2-(2-chlorophenyl)cyclohexanone." Acta Crystallographica Section E Structure Reports Online 67, no. 4 (2011): o936. http://dx.doi.org/10.1107/s1600536811009950.

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21

Lynch, Daniel E., Ajmer S. Bening, and Simon Parsons. "Tris(2-ammonioethyl)amine tris({2-[(2,6-dichlorophenyl)amino]phenyl}acetate) hexahydrate." Acta Crystallographica Section E Structure Reports Online 59, no. 9 (2003): o1314—o1317. http://dx.doi.org/10.1107/s1600536803017926.

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22

Kobayashi, Fumiya, Atsushi Koga, Ryo Ohtani, Shinya Hayami, and Masaaki Nakamura. "Crystal structure of [2-({2-[(2-azanidylbenzylidene)amino]benzylidene}amino)-4-chlorophenolato]nickel(II)." Acta Crystallographica Section E Crystallographic Communications 73, no. 4 (2017): 637–39. http://dx.doi.org/10.1107/s2056989017004613.

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The title complex, [Ni(C20H14ClN3O)], with an asymmetrically chloride-appended Schiff base ligand has been synthesized and structurally characterized at 100 K. In the compound, the central nickel(II) ion has a square-planar coordination geometry with N3O donors of the π-conjugated tetradentate Schiff base ligand. In the crystal, the complexes are connected into an inversion dimerviaan Ni...Ni interaction [3.1753 (5) Å] and a pair of π–π interactions [centroid–centroid distance = 3.8416 (16) Å]. The dimers are linkedviaa C—H...Cl hydrogen bond, forming a chain along thec-axis direction. The dim

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23

Babu, K. Syed Suresh, G. Peramaiyan, M. NizamMohideen, and R. Mohan. "2-Amino-6-methylpyridinium 2,2,2-trichloroacetate." Acta Crystallographica Section E Structure Reports Online 70, no. 4 (2014): o391—o392. http://dx.doi.org/10.1107/s1600536814004553.

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In the asymmetric unit of the title molecular salt, C6H9N2+·C2Cl3O2−, there are two independent 2-amino-6-methylpyridinium cations and two independent trichloroacetate anions. The pyridine N atom of the 2-amino-6-methylpyridine molecule is protonated and the geometries of these cations reveal amine–imine tautomerism. Both protonated 2-amino-6-methylpyridinium cations are essentially planar [maximum deviations = 0.026 (2) and 0.012 (2) Å]. In the crystal, the protonated N atom and the 2-amino group of the cation are hydrogen bonded to the carboxylate O atoms of the anionviaa pair of N—H...O hyd

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24

Villemin, Didier, Bernard Moreau, and Nathalie Bar. "MCR under Microwave Irradiation: Synthesis in Water of New 2-Amino-bis(2-phosphonoacetic) Acids." Organics 2, no. 2 (2021): 98–106. http://dx.doi.org/10.3390/org2020009.

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Novel 2-amino bis(2-phosphonoacetic) acids were prepared by microwave irradiation of a mixture of amine, glyoxylic acid and phosphorous acid. The reaction takes place with various amines including primary and secondary amines and polyamines, but this reaction is more sensitive to steric hindrance of amine than the similar Kabachnik–Fields reaction. Amino acids can be also transformed into the expected bis(2-phosphonoacetic) acids, with the exception of tryptophan, which gives a β-carboline product.

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25

Xing, Zhi-Yong, Hui-Min Liu, Li Wu, and Wen-Qin Zhang. "2-Amino-2′-chloro-5-methylbenzophenone." Acta Crystallographica Section E Structure Reports Online 61, no. 11 (2005): o3796—o3797. http://dx.doi.org/10.1107/s1600536805033313.

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26

Hemamalini, Madhukar, and Hoong-Kun Fun. "2-Amino-4-methylpyridinium 2-hydroxybenzoate." Acta Crystallographica Section E Structure Reports Online 66, no. 8 (2010): o2151—o2152. http://dx.doi.org/10.1107/s160053681002965x.

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27

Quah, Ching Kheng, Madhukar Hemamalini, and Hoong-Kun Fun. "2-Amino-5-bromopyridinium 2-hydroxybenzoate." Acta Crystallographica Section E Structure Reports Online 66, no. 8 (2010): o2164—o2165. http://dx.doi.org/10.1107/s1600536810029855.

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28

Hemamalini, Madhukar, and Hoong-Kun Fun. "2-Amino-5-methylpyridinium 2-carboxybenzoate." Acta Crystallographica Section E Structure Reports Online 66, no. 9 (2010): o2192—o2193. http://dx.doi.org/10.1107/s160053681003000x.

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29

Quah, Ching Kheng, Madhukar Hemamalini, and Hoong-Kun Fun. "2-Amino-5-methylpyridinium 2-hydroxybenzoate." Acta Crystallographica Section E Structure Reports Online 66, no. 9 (2010): o2255—o2256. http://dx.doi.org/10.1107/s1600536810030928.

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30

Quah, Ching Kheng, Madhukar Hemamalini, and Hoong-Kun Fun. "2-Amino-5-bromopyridinium 2-carboxybenzoate." Acta Crystallographica Section E Structure Reports Online 66, no. 9 (2010): o2269—o2270. http://dx.doi.org/10.1107/s1600536810030977.

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31

Thanigaimani, Kaliyaperumal, Abbas Farhadikoutenaei, Nuridayanti Che Khalib, Suhana Arshad, and Ibrahim Abdul Razak. "2-Amino-5-methylpyridinium 2-aminobenzoate." Acta Crystallographica Section E Structure Reports Online 68, no. 11 (2012): o3196—o3197. http://dx.doi.org/10.1107/s1600536812043243.

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32

Muralidharan, Srinivasan, Narayanan Elavarasu, Thothadri Srinivasan, Rengasamy Gopalakrishnan, and Devadasan Velmurugan. "2-Amino-4-methylpyridinium 2-nitrobenzoate." Acta Crystallographica Section E Structure Reports Online 69, no. 6 (2013): o910. http://dx.doi.org/10.1107/s1600536813012919.

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33

Schwalbe, C. H. W., S. Freeman, and M. DasGupta. "2-Amino-2-carboxyethylphosphinic acid monohydrate." Acta Crystallographica Section C Crystal Structure Communications 49, no. 10 (1993): 1826–28. http://dx.doi.org/10.1107/s0108270193003683.

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34

Cox, P. J., A. T. Md Anisuzzaman, R. H. Pryce-Jones, N. Shankland, and G. G. Skellern. "2-(2-Amino-5-bromobenzoyl)pyridine." Acta Crystallographica Section C Crystal Structure Communications 52, no. 4 (1996): 929–31. http://dx.doi.org/10.1107/s0108270195014776.

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35

Seela, Frank, Xiaohua Peng, Henning Eickmeier, and Hans Reuter. "2-Amino-7-chloro-2′-deoxytubercidin." Acta Crystallographica Section C Crystal Structure Communications 62, no. 10 (2006): o593—o595. http://dx.doi.org/10.1107/s0108270106032227.

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36

Hemamalini, Madhukar, Ibrahim Abdul Razak, and Hoong-Kun Fun. "2-Amino-6-methylpyridinium 2-carboxybenzoate." Acta Crystallographica Section E Structure Reports Online 67, no. 9 (2011): o2402. http://dx.doi.org/10.1107/s1600536811033174.

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37

Hemamalini, Madhukar, and Hoong-Kun Fun. "2-Amino-5-methylpyridinium 2-carboxyacetate." Acta Crystallographica Section E Structure Reports Online 66, no. 6 (2010): o1480—o1481. http://dx.doi.org/10.1107/s1600536810019239.

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38

Hemamalini, Madhukar, and Hoong-Kun Fun. "2-Amino-5-chloropyridinium 2-carboxyacetate." Acta Crystallographica Section E Structure Reports Online 66, no. 6 (2010): o1496—o1497. http://dx.doi.org/10.1107/s1600536810019677.

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39

Quah, Ching Kheng, Madhukar Hemamalini, and Hoong-Kun Fun. "2-Amino-4-methylpyridinium 2-carboxybenzoate." Acta Crystallographica Section E Structure Reports Online 66, no. 8 (2010): o1932. http://dx.doi.org/10.1107/s1600536810025900.

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40

Pushkal, Samadhiya, Sharma Ritu, K. Srivastava S., and D. Srivastava S. "Synthesis and biological evaluation of some 2-amino-5-nitrothiazole derivatives of azetidine." Journal of Indian Chemical Society Vol. 90, Feb 2013 (2013): 231–38. https://doi.org/10.5281/zenodo.5767700.

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Synthetic Organic Chemistry Laboratory, Department of Chemistry, Dr. H. S. Gour University (A Central University), Sagar-470 003, Madhya Pradesh, India <em>E-mail</em> : pushkalsamadhiya@rediffmail.com <em>Manuscript received O1 August 2011, revised 29 February 2012, accepted 17 April 2012</em> A series of <em>N</em>-[2-(2-amino-5-nitrothiazolyl)ethyl]-4-(substituted phenyl)-3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-j) have been synthesized from 2-amino-5-nitrothiazole as a starting material in four steps. The structure of all the synthesized compounds were confirmed by chemical and

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41

Arumugam, Natarajan, Aisyah Saad Abdul Rahim, Shafida Abd. Hamid, Mohd Mustaqim Rosli, and Hoong-Kun Fun. "Ethyl 3-amino-4-[(2-hydroxyethyl)amino]benzoate." Acta Crystallographica Section E Structure Reports Online 66, no. 8 (2010): o2141. http://dx.doi.org/10.1107/s1600536810029077.

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42

Ma, Xiang-Jun, Zheng Fang, Li-Li Ren, and Ping Wei. "5-Amino-2-methylbenzenesulfonamide." Acta Crystallographica Section E Structure Reports Online 65, no. 8 (2009): o1815. http://dx.doi.org/10.1107/s1600536809026142.

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43

Shah Bakhtiar, Nasir, Zanariah Abdullah, and Seik Weng Ng. "4-Amino-2-phenoxypyrimidine." Acta Crystallographica Section E Structure Reports Online 65, no. 8 (2009): o1858. http://dx.doi.org/10.1107/s1600536809026580.

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44

Yamamoto, Emi, Kanji Kubo, Nobuo Kato, and Akira Mori. "2-Amino-5-hexyloxytropone." Acta Crystallographica Section E Structure Reports Online 57, no. 3 (2001): o279—o281. http://dx.doi.org/10.1107/s1600536801003294.

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45

Baker, L.-J., Brent R. Copp, and Clifton E. F. Rickard. "2′-Amino-5′-bromoacetophenone." Acta Crystallographica Section E Structure Reports Online 57, no. 6 (2001): o540—o541. http://dx.doi.org/10.1107/s160053680100839x.

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46

Au-Alvarez, O., R. C. Peterson, A. Acosta Crespo, et al. "2-Amino-4-phenylthiazole." Acta Crystallographica Section C Crystal Structure Communications 55, no. 5 (1999): 821–23. http://dx.doi.org/10.1107/s0108270199001961.

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47

Qian, Shao-Song, Hao Hu, and Hong-You Cui. "2-Amino-4-methylbenzenesulfonamide." Acta Crystallographica Section E Structure Reports Online 65, no. 10 (2009): o2513. http://dx.doi.org/10.1107/s1600536809037271.

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48

Yin, Yongbiao. "2-Amino-2,3-dimethylbutanamide." Acta Crystallographica Section E Structure Reports Online 66, no. 6 (2010): o1258. http://dx.doi.org/10.1107/s1600536810015679.

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49

Kesternich, Víctor, Paulo Gahona, Marcia Pérez-Fehrmann, Iván Brito, and Matías López-Rodríguez. "2-Amino-N′-phenylbenzohydrazide." Acta Crystallographica Section E Structure Reports Online 68, no. 6 (2012): o1847. http://dx.doi.org/10.1107/s1600536812022362.

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In the title compound, C13H13N3O, the NNCO unit forms dihedral angles of 35.8 (1) and 84.0 (1)° with the benzene and phenyl rings, respectively. The dihedral angles between the aromatic rings is 61.2 (1)°. An intramolecular N—H...O hydrogen bond occurs. In the crystal, molecules are linked by weak N—H...O hydrogen bonds into C(4) chains parallel to the c axis. Neighbouring chains are linked by weak N—H...N hydrogen bonds, forming R 4 4(20) rings, and resulting in the formation of a two-dimensional network lying parallel to (010). The packing also features π–π stacking interactions between phen

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50

Kargar, Hadi, Reza Kia, and Muhammad Nawaz Tahir. "4-Amino-2-hydroxybenzohydrazide." Acta Crystallographica Section E Structure Reports Online 68, no. 7 (2012): o2117. http://dx.doi.org/10.1107/s1600536812026190.

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