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Relevant bibliographies by topics / 2-Aminopyridine-3-carboxylic acid

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Journal articles

Academic literature on the topic '2-Aminopyridine-3-carboxylic acid'

Author: Grafiati

Published: 5 June 2025

Last updated: 16 July 2025

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Journal articles on the topic "2-Aminopyridine-3-carboxylic acid"

1

Marandi, Ghasem. "Synthesis of 3-(Cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8- carboxylic Acids Via an Efficient Three-component Condensation Reaction between Cyclohexylisocyanide and 2-Aminopyridine-3-carboxylic Acid in the Presence of Aromatic Aldehyde." Combinatorial Chemistry & High Throughput Screening 21, no. 4 (2018): 298–301. http://dx.doi.org/10.2174/1386207321666180416153112.

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Aim and Objective: The reaction of cyclohexylisocyanide and 2-aminopyridine-3- carboxylic acid in the presence of benzaldehyde derivatives in ethanol led to 3-(cyclohexylamino)-2- arylimidazo[1,2-a]pyridine-8-carboxylic acids in high yields. In a three component condensation reaction, isocyanide reacts with 2-aminopyridine-3-carboxylic acid and aromatic aldehydes without any prior activation. Material and Methods: The synthesized products have stable structures which have been characterized by IR, 1H, 13C and Mass spectroscopy as well as CHN-O analysis. Results: In continuation of our attempts

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2

A. Jackson, Yvette, and Mark F. Williams. "Heterocycles from 2-Aminopyridine and Derivatives of 3-Methylbenzofuran-2-carboxylic Acid." HETEROCYCLES 45, no. 4 (1997): 787. http://dx.doi.org/10.3987/com-96-7660.

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3

Wang, Dan, Shu-Mu Li, Yu-Fei Li, Xiang-Jun Zheng, and Lin-Pei Jin. "Hydrogen bond-assisted aggregation-induced emission and application in the detection of the Zn(ii) ion." Dalton Transactions 45, no. 20 (2016): 8316–19. http://dx.doi.org/10.1039/c6dt00265j.

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3-Aminopyridine-2-carboxylic acid can serve as an AIE-active turn on fluorescence chemosensor for Zn<sup>2+</sup>. The AIE behaviors are attributed to the cooperative effect of J-aggregation and hydrogen bonds. And selecting proper ratio of the solvents can prove the sensitivity.

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4

JACKSON, Y. A., and M. F. WILLIAMS. "ChemInform Abstract: Heterocycles from 2-Aminopyridine and Derivatives of 3- Methylbenzofuran-2-carboxylic Acid." ChemInform 28, no. 41 (2010): no. http://dx.doi.org/10.1002/chin.199741139.

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5

Chen, QP, and LW Deady. "Synthesis of Some Benzo[b][1,6]naphthyridines and Benzo[b][1,7]naphthyridines." Australian Journal of Chemistry 46, no. 7 (1993): 987. http://dx.doi.org/10.1071/ch9930987.

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Pfitzinger (1-benzylpiperidin-4-one with 7-methylisatin) and Friedlander (3-aminopyridine-4-carbaldehyde with 2-methylcyclohexanone) syntheses, respectively, were used to prepare the title 'azaacridines' containing a methyl substituent peri to the central nitrogen. Oxidation of this group gave the corresponding aldehyde and carboxylic acid. In the [1,6] case, especially, the 10-position was also easily oxidized to give acridone analogues. Nitration occurred exclusively in the benzenoid rings.

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6

Putaya, Habila A. N., Naomi P. Ndahi, Hauwa S. Bello, Grema Mala, Adekunle A. Osunlaja, and Hussaini Garba. "Synthesis, characterization and antimicrobial analysis of Schiff bases of o-phenylenediamine and 2-aminopyridine-3-carboxylic acid with ofloxacin and their metal (II) complexes." International Journal of Biological and Chemical Sciences 14, no. 1 (2020): 263–78. http://dx.doi.org/10.4314/ijbcs.v14i1.22.

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The increasing multi-drug resistance of microbes to the existing anti-biotic drugs has been of great concern to medical scientists and challenge has directly concerned pharmacologists, inorganic chemists, molecular microbiologists etc. This work attempted modifying a second generation fluoroquinolone (ofloxacin) toward attaining more improved activity. Schiff base Ligands HL1 and HL2 were obtained from separate condensation of o-phenylenediamine and 2-aminopyridine-3-carboxylic acid with ofloxacin in 2:1 and 1:1 mole ratio respectively. These ligands were complexed with chloride salts of Ni (I

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7

de Mesquita, Maria E., Gilberto F. de Sá, and Oscar L. Malta. "Spectroscopic studies of the Eu(III) and Gd(III) tris(3-aminopyridine-2-carboxylic acid) complexes." Journal of Alloys and Compounds 250, no. 1-2 (1997): 417–21. http://dx.doi.org/10.1016/s0925-8388(96)02561-3.

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8

Habila, A. N. Putaya, P. Ndahi Naomi, Mala Grema, Z. Kyari Modu, and Garba Hussaini. "Synthesis, Characterization and Antimicrobial Assessment of Ofloxacin Derivatives and Their Complexes with Cobalt(II) and Copper(II) Metals." Chemistry Research Journal 4, no. 4 (2019): 23–34. https://doi.org/10.5281/zenodo.13312285.

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Schiff base Ligands HL<sup>1</sup> and HL<sup>2</sup> were synthesized by separate condensation of o-phenylenediamine and 2-aminopyridine-3-carboxylic acid with ofloxacin in 2:1 and 1:1 mole ratio respectively. These ligands were reacted with chloride salts of Co(II)  and Cu(II) to obtain (HL<sup>1</sup>) and (HL<sup>2</sup>)-Metal complexes respectively. The novel compounds were characterized using physicochemical properties, IR spectroscopy, UV-visible spectroscopy, Molar conductance and metal analysis. The IR and UV/vis spectra revealed that the metal ions coordinated with the ligands

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9

Prakash, Shet M., S. Naveen, N. K. Lokanath, P. A. Suchetan, and Ismail Warad. "Crystal structures of 2-aminopyridine citric acid salts: C5H7N2 +·C6H7O7 − and 3C5H7N2 +·C6H5O7 3−." Acta Crystallographica Section E Crystallographic Communications 74, no. 8 (2018): 1111–16. http://dx.doi.org/10.1107/s2056989018009787.

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2-Aminopyridine and citric acid mixed in 1:1 and 3:1 ratios in ethanol yielded crystals of two 2-aminopyridinium citrate salts, viz. C5H7N2 +·C6H7O7 − (I) (systematic name: 2-aminopyridin-1-ium 3-carboxy-2-carboxymethyl-2-hydroxypropanoate), and 3C5H7N2 +·C6H5O7 3− (II) [systematic name: tris(2-aminopyridin-1-ium) 2-hydroxypropane-1,2,3-tricarboxylate]. The supramolecular synthons present are analysed and their effect upon the crystal packing is presented in the context of crystal engineering. Salt I is formed by the protonation of the pyridine N atom and deprotonation of the central carboxyli

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10

Srivastava, Ashish Kumar, Krishna Srivastava, and Jagdish Prasad. "Synthesis, characterization, spectroscopic and electrochemical investigation of 2-aminopyridine-3-carboxylic acid copper(II) complexes with diimine." Chemical Data Collections 24 (December 2019): 100272. http://dx.doi.org/10.1016/j.cdc.2019.100272.

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