Relevant bibliographies by topics / 2-aminopyrimidine

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic '2-aminopyrimidine'

Author: Grafiati
Published: 4 June 2021
Last updated: 27 July 2025

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Journal articles on the topic "2-aminopyrimidine"

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Zhao, Mingzhu, Juewang Cai, and Xiaoming Zhao. "Silver-promoted selective fluorination of 2-aminopyrimidines: synthesis of 5-fluoro-2-aminopyrimidine derivatives." Organic Chemistry Frontiers 6, no. 4 (2019): 426–31. http://dx.doi.org/10.1039/c8qo01054d.

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Ag-Promoted selective fluorination of 2-aminopyrimidine derivatives with Selectfluor is presented, giving 4-substituted 5-fluoro-2-aminopyrimidines in fair to high yields with excellent regioselectivities.
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Kloda, Matouš, Irena Matulková, Ivana Císařová, et al. "Cocrystals of 2-Aminopyrimidine with Boric Acid—Crystal Engineering of a Novel Nonlinear Optically (NLO) Active Crystal." Crystals 9, no. 8 (2019): 403. http://dx.doi.org/10.3390/cryst9080403.

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Crystal engineering of novel materials for nonlinear optics (NLO) based on 2-aminopyrimidine yielded two molecular cocrystals with boric acid—trigonal (P3221 space group) 2-aminopyrimidine—boric acid (3/2) and monoclinic (C2/c space group) 2-aminopyrimidine—boric acid (1/2). In addition to crystal structure determination by single crystal X-ray diffraction, the cocrystals were characterized by powder X-ray diffraction and vibrational spectroscopy (FTIR and FT Raman). Large single crystals of the non-centrosymmetric cocrystal 2-aminopyrimidine—boric acid (3/2) were grown to study the optical pr
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Lumme, P. O., H. Knuuttila та E. Lindell. "Di-μ-sulfato-O:O'-bis[(2-aminopyrimidine-N1)triaquacobalt(II)] Dihydrate (1), catena-Poly[bis(2-aminopyrimidine-N1)diaquanickel(II)-μ-sulfato-O:O' 2-Aminopyrimidine] (2), (2-Aminopyrimidine-N1)pentaaquanickel(II) Sulfate 2-Aminopyrimidine (3) and catena-Poly[bis(2-aminopyrimidine-N1)aquacopper(ii)-μ-sulfato-O:O' Dihydrate] (4)". Acta Crystallographica Section C Crystal Structure Communications 52, № 1 (1996): 51–56. http://dx.doi.org/10.1107/s0108270195001338.

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Hoffelner, Michael, Usama Hassan, Werner Seebacher, et al. "New 2-aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities." Monatshefte für Chemie - Chemical Monthly 151, no. 9 (2020): 1375–85. http://dx.doi.org/10.1007/s00706-020-02674-7.

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Abstract Novel 2-aminopyrimidine derivatives were prepared from acyclic starting materials, benzylidene acetones and ammonium thiocyanates, via 5 steps, including ring closure, aromatization, S-methylation, oxidation to methylsulfonyl compounds, and formation of guanidines with suitable amines. The prepared compounds differ from each other by the substitutions of their amino group and of their phenyl ring. The 2-aminopyrimidines were tested by use of microplate assays for their in vitro activities against a causative organism of sleeping sickness, Trypanosoma brucei rhodesiense, as well as aga
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Kwiecień, Anna, and Zbigniew Ciunik. "Stable Hemiaminals: 2-Aminopyrimidine Derivatives." Molecules 20, no. 8 (2015): 14365–76. http://dx.doi.org/10.3390/molecules200814365.

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Goswami, S., A. K. Mahapatra, G. D. Nigam, K. Chinnakali, H. K. Fun, and I. A. Razak. "2-Aminopyrimidine–fumaric acid cocrystal." Acta Crystallographica Section C Crystal Structure Communications 55, no. 4 (1999): 583–85. http://dx.doi.org/10.1107/s0108270198014127.

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Manorama, Garima Awasthi. "A Overview Of The 2-Aminopyrimidine Derivatives As Antimicrobial Agents." International Journal of Pharmaceutical Sciences 2, no. 8 (2024): 2420–26. https://doi.org/10.5281/zenodo.13167948.

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The ongoing challenge of antimicrobial resistance necessitates the continuous exploration of new antimicrobial agents. Among various chemical scaffolds, 2-aminopyrimidine derivatives have garnered significant attention due to their broad-spectrum antimicrobial properties. This review provides a comprehensive overview of 2-aminopyrimidine derivatives, highlighting their chemical synthesis, structural diversity, and mechanisms of action. Emphasis is placed on recent advancements in the development of these compounds, their activity against a variety of microbial pathogens, and their potential as
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Petrova, Olga V., Arsalan B. Budaev, Elena F. Sagitova, et al. "Pyrrole–Aminopyrimidine Ensembles: Cycloaddition of Guanidine to Acylethynylpyrroles." Molecules 26, no. 6 (2021): 1692. http://dx.doi.org/10.3390/molecules26061692.

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An efficient method for the synthesis of pharmaceutically prospective pyrrole–aminopyrimidine ensembles (in up to 91% yield) by the cyclocondensation of easily available acylethynylpyrroles with guanidine nitrate has been developed. The reaction proceeds under heating (110–115 °C, 4 h) in the KOH/DMSO system. In the case of 2-benzoylethynylpyrrole, the unexpected addition of the formed pyrrole–aminopyrimidine as N- (NH moiety of the pyrrole ring) and C- (CH of aminopyrimidine) nucleophiles to the triple bond is observed.
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Wang, Li-Hua, Fan-Yuan Kong, and Xi-Shi Tai. "Crystal Structure and Catalytic Activity of Poly[bis(3-bromo-2-hydroxybenzaldehyde)-2-aminopyrimidinemagnesium(II)] for Hydrogenation of 1,3-Butadiene." Bulletin of Chemical Reaction Engineering & Catalysis 16, no. 2 (2021): 260–66. http://dx.doi.org/10.9767/bcrec.16.2.10421.260-266.

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A new six-coordinated Mn(II) coordination polymer, [Mn(L1)(L2)2]n (L1 = 2-aminopyrimidine, HL2 = 3-bromo-2-hydroxybenzaldehyde) was synthesized by 3-bromo-2-hydroxybenzaldehyde, NaOH, 2-aminopyrimidine and manganese(II) acetate dihydrate. The Mn(II) coordination polymer was structural characterized by elemental analysis and single crystal X-ray diffraction. The results show that each Mn(II) ion is six-coordinated with two phenolic hydroxyl O atoms from two 3-bromo-2-hydroxybenzaldehyde ligands (O1 and O4), two formyl group O atoms from two 3-bromo-2-hydroxybenzaldehyde ligands (O2 and O3), and
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Lin, Zhi-Dong, та Wen Zeng. "Bis(2-aminopyrimidine-κN1)dichloridozinc(II)". Acta Crystallographica Section E Structure Reports Online 63, № 6 (2007): m1597. http://dx.doi.org/10.1107/s1600536807021575.

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Dissertations / Theses on the topic "2-aminopyrimidine"

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Haycock, Meghan Lynn. "Towards Fluorinated Substrate Analogs and N-Acylated 2-Aminopyrimidine Inhibitors of Lipoxygenases." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31520.

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Cyclooxygenase (COX) and lipoxygenase (LOX) catalyze the rate-determining step in the production of arachidonic acid- derived signaling molecules (eicosanoids) within the body. COX has been extensively investigated, which has enabled the design of non-steroidal inflammatory drugs (NSAIDs) such as aspirin, acetaminophen (ApAP) and ibuprofen. However, there are still fundamental questions surrounding the LOX family of enzymes, which has limited the development of isoform specific inhibitors. The structural basis and regio- and stereoselectivity of the LOX isoforms are not known. Herein, we desc
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Eberhard, Jens [Verfasser]. "Funktionalisierte 2-Aminopyrimidine und 2,2':6',2''-Terpyridine und ihre Koordinationsverbindungen : Synthese und optische Eigenschaften / Jens Eberhard." Bielefeld : Universitätsbibliothek Bielefeld, 2014. http://d-nb.info/1051077087/34.

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Löpfe, Michael Löpfe Michael. "Synthesis of carbon-analogues of 2,4-diaminopyrimidine and 2-oxo-4-aminopyrimidine homo-DNA nucleosides : Study of homo-DNA oligonucleotides containing carbon-analogues of the 2,4-diaminopyrimidine nucleotide /." [S.l.] : [s.n.], 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000286574.

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Robinson, Sarel Johannes. "Syntheses of chalcones and 2-aminopyrimidines and their evaluation as monoamine oxidase inhibitors and as adenosine receptor antagonists / Sarel Johannes Robinson." Thesis, North-West University, 2013. http://hdl.handle.net/10394/9534.

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Background and rationale - Parkinson’s disease is a neurodegenerative disorder characterised by reduced levels of dopamine in the brain. The cause of Parkinson's disease is still unknown; however several theories pertaining to the etiology exist. Current treatment mainly aims at dopamine replacement, with agents such as levodopa and dopamine agonists that provide patients with symptomatic relief. This relief is unfortunately only temporary as the progression of the disease is not halted. Furthermore, these therapies are associated with a range of side effects and novel approaches to the treat
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Chu, Kuan-Lun, and 朱冠綸. "Study on Ag( I )complexes Bearing 2-Aminopyrimidine." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/6jgzms.

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碩士<br>中原大學<br>化學研究所<br>92<br>Abstract A series of silver (I) complexes of the types {[Ag2(L2)( PF6)]}∞ , 1; {[Ag2(L2)( SO4)]}∞ , 2 ; [Ag(L2)( PF6)] , 3; {[Ag(L1.5)(ClO4)]}∞, 4 ;{[Ag(L)(OAc)]}∞, 5 have been prepared by the reactions AgX(X = PF6�{ , ClO4�{ , OAc �{)and Ag2SO4 . All the complexes have been structurally characterized by X-ray crystallograply. Complexes,1、2 and 4 form two-dimensional structures while complex 3 is mononuclear,complex 5 is one-dimension Zigzag Chain.
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Tsao, Tsu-Hsien, and 曹祖憲. "Synthesis and Reactivity of Ruthenium Complexes Containing 2-Aminopyrimidine Ligand." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/81861717191525872376.

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碩士<br>臺北市立大學<br>應用物理暨化學系<br>104<br>In this study, our research objectives are focused on designing novel ruthium complexes and understand the relations between catalysis mechanism and chemical structure. For two-year efforts, there are two main research achievement as shown below： (a) Treatment of TpRu(PPh3)2Cl (4) with 2-aminopyrimidine afforded to TpRu(PPh3)(2-aminopyrimidine)Cl (5). The structures of complex 5 have been determined by X-ray diffraction analysis. (b) We also have used to theoretical calculations for the reaction of ruthenium complex to support our purposed mechanism.
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Kloda, Matouš. "Příprava a studium nových krystalických materiálů pro nelineární optiku odvozených od dusíkatých heterocyklů." Doctoral thesis, 2019. http://www.nusl.cz/ntk/nusl-404297.

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The presented Ph.D. thesis is aimed at the preparation and characterisation of novel crystalline materials with application potential in nonlinear optics (NLO). The main goal was preparation of crystalline salts and adducts (cocrystals) of selected nitrogen-containing heterocycles with a range of organic and inorganic acids. Based on previous study and quantum- chemical calculations, the following starting heterocycles were selected: 2-aminopyrimidine, 4-aminopyrimidine, 5-aminopyrimidine, 3-amino-1,2,4-triazine and 3-amino-5,6-dimethyl- 1,2,4-triazine. The prepared materials were characterise
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Jeng, Cang-Sian, and 鐘蒼賢. "Synthesis and structures of Zn(II) compounds containing 2-aminopyrimidine or 2-amino-4-methylpyrimidine." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/96520855716850152942.

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碩士<br>中原大學<br>化學研究所<br>97<br>The syntheses and structures of a series of zinc compounds [ZnCl2(L1)2] (L1 = 2-Aminopyrimidine), 1; [ZnBr2(L1)2], 2; [ZnI2(L1)2], 3; [ZnBr(OH)(L1)]n, 4; [Zn(NO3)(OH)(L1)]n, 5; [ZnCl2(L2)2] (L2 = 2-Amino-4-methylpyrimidine), 6; [ZnBr2(L2)2], 7; [ZnI2(L2)2], 8, are reported. All compounds have been structurally characterized by X-ray crystallography. Compounds 1 - 3 are same configuration as well as compounds 6 - 8, which consist of a central zinc(II) metal centers coordinated by two organic ligands and two anions, forming a tetrahedral geometry. The C–H---X, N–H---
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Lin, Hsiao-Ting, and 林孝庭. "Synthesis and Related Reactions of New Ruthenium Azido Complexes Containing 2-Aminopyrimidine Ligands." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/9va3g8.

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碩士<br>臺北市立大學<br>應用物理暨化學系<br>107<br>The reaction of a novel ruthenium azido complex Tp(PPh3)(L)Ru-N3 have been investigated. By reacting with different ligands (L), discussing its different chemical properties and related catalytic reactions. Treatment of Tp(PPh3)2Ru-Cl with 2-Aminopyrimidine afforded ruthenium halide complex Tp(PPh3)(H2NC4H3N2)Ru-Cl (2c), addition of NaN3 to 2c produces the azido complex Tp(PPh3)(H2NC4H3N2)Ru-N3 (3c). Furthermore, the metal-bound heterocyclic complex Tp(PPh3)(H2NC4H3N2)Ru[N3C2(CO2CH3)2] (4) is obtained from dimethyl acetylene dicarboxylate. The reaction of P
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Kleynhans, Janke. "Aminopyrimidine derivatives as adenosine antagonists / Janke Kleynhans." Thesis, 2013. http://hdl.handle.net/10394/10857.

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Aims of this project - The aim of this study was to design and synthesise novel 2-aminopyrimidine derivatives as potential adenosine A1 and A2A receptor antagonists. Background and rationale - Parkinson’s disease is the second most common neurodegenerative disorder (after Alzheimer’s disease) and is characterised by the selective death of the dopaminergic neurons of the nigro-striatal pathway. Distinctive motor symptoms include bradykinesia, muscle rigidity and tremor, while non-motor symptoms, of which cognitive dysfunction is an example, also frequently occur. Current therapy provides sympto
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Book chapters on the topic "2-aminopyrimidine"

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex of 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-49202-4_55.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of cobalt(II) complex of 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45972-0_479.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex of 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45972-0_581.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex with dicyanamide and 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53971-2_754.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of μ-hydroxo bridged binculear copper(II) complex with 2-aminopyrimidine." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 4. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62474-6_216.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand copper(II) complex with Schiff-base derived from thiophene-2-glyoxal and 2-aminopyrimidine and chloride." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_254.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand copper(II) complex with Schiff-base derived from thiophene-2-glyoxal and 2-aminopyrimidine and chloride." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_255.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand copper(II) complex with Schiff-base derived from thiophene-2-glyoxal and 2-aminopyrimidine and ammonia." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_256.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand copper(II) complex with Schiff-base derived from thiophene-2-glyoxal and 2-aminopyrimidine and thiourea." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_257.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand copper(II) complex with Schiff-base derived from thiophene-2-glyoxal and 2-aminopyrimidine and thiourea." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_258.

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Conference papers on the topic "2-aminopyrimidine"

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Vargas, Pâmela S. de, Helio G. Bonacorso, Nilo Zanatta, Clarissa P. Frizzo, and Marcos A. P. Martins. "Microwave-assisted Synthesis of New Ethyl 2-aminopyrimidine- 4-carboxylates." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013914191433.

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