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Relevant bibliographies by topics / 2-azabicyclo[3.3.1]octane

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Journal articles

Academic literature on the topic '2-azabicyclo[3.3.1]octane'

Author: Grafiati

Published: 9 March 2023

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Journal articles on the topic "2-azabicyclo[3.3.1]octane"

1

Kumaran, D., M. N. Ponnuswamy, G. Shanmugam, et al. "Molecular structures and conformations of three 3-azabicyclononanes." Acta Crystallographica Section B Structural Science 55, no. 5 (1999): 793–98. http://dx.doi.org/10.1107/s0108768199005273.

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The structure, conformation, molecular geometry and the mode of packing of 7-tert-butyl-N-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonane (C25H33N; MTABN), N-acetyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonane (C22H25NO; AABN) and N-methyl-2,4-bis(2-methylphenyl)-3-azabicyclo[3.3.1]nonan-9-ol (C23H29NO; MHABN) are presented. The compounds MTABN and MHABN crystallize in monoclinic space groups, whereas AABN is orthorhombic. In each of the three structures, the bicyclic ring system adopts a chair–chair conformation and the phenyl rings are in equatorial orientation with respect to the piperidine ring. I

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2

Bonjoch, Josep, Nuria Casamitjana, Josefina Quirante, Antoni Torrens, Anna Paniello, and Joan Bosch. "Functionalized 2-azabicyclo[3.3.1] nonanes. vii." Tetrahedron 43, no. 2 (1987): 377–81. http://dx.doi.org/10.1016/s0040-4020(01)89966-x.

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3

Bonjoch, Josep, Faïza Diaba, and Ben Bradshaw. "Synthesis of 2-Azabicyclo[3.3.1]nonanes." Synthesis 2011, no. 07 (2011): 993–1018. http://dx.doi.org/10.1055/s-0030-1258420.

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4

Parthiban, P., V. Ramkumar, Min Sung Kim, Se Mo Son, and Yeon Tae Jeong. "2,4-Bis(2-methoxyphenyl)-3-azabicyclo[3.3.1]nonan-9-one." Acta Crystallographica Section E Structure Reports Online 65, no. 6 (2009): o1383. http://dx.doi.org/10.1107/s1600536809018686.

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In the title compound, C22H25NO3, the molecule has a pseudo-mirror plane. The structure is a positional isomer of 2,4-bis(4-methoxyphenyl)-3-azabicyclo[3.3.1]nonan-9-one [Cox, McCabe, Milne & Sim (1985).J. Chem. Soc. Chem. Commun.pp. 626–628]. The 3-azabicyclo[3.3.1]nonan-9-one moiety adopts a double chair conformation with equatorial orientations of both 2-methoxyphenyl substituents on either side of the secondary amino group. The benzene rings are oriented at an angle of 33.86 (4)° with respect to each other and the methoxy groups point towards the carbonyl group. The crystal structure i

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5

Rao, T. N., Y. Prasanthi, Parvatamma Botsa, G. Kumara, and K. A. Rao. "A NEW METHOD DEVELOPMENT AND VALIDATION FOR RELATED SUBSTANCES OF GRANISETRON IN ACTIVE PHARMA INGREDIENT BY HPLC." INDIAN DRUGS 54, no. 07 (2017): 52–59. http://dx.doi.org/10.53879/id.54.07.10746.

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A simple and inexpensive method was developed using high performance liquid chromatography with PDA detection for determination of granisetron hydrochloride and related impurities (2-methyl-N- [(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-2H-indazole-3-carboxamide, 1-Methyl-N-[(1R,3r,5S)- 9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride, N-[(1R,3r,5S)-9- azabicyclo[3.3.1]non-3-yl]-1-methyl-1H-indazole-3-carboxamide and 1-methyl-1H-indazole-3-carboxylic acid. The chromatographic separations were achieved on (250×4.6 mm), 5.0 μm make: Waters, Symmetry Shield C8 c

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6

Eckermann, Ruben, Michael Breunig, and Tanja Gaich. "Formal total synthesis of (±)-strictamine – the [2,3]-Stevens rearrangement for construction of octahydro-2H-2,8-methanoquinolizines." Chemical Communications 52, no. 76 (2016): 11363–65. http://dx.doi.org/10.1039/c6cc06125g.

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7

Liu, Yan-Qing, He Liu, Bo-hua Zhong, Yu-Lin Deng, and Ke-liang Liu. "Synthesis and Crystal Structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)Acetate Hydrochloride." Journal of Chemical Research 2005, no. 7 (2005): 436–37. http://dx.doi.org/10.3184/030823405774309041.

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(9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.

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8

Carman, Raymond M., and Roger P. C. Derbyshire. "Azacineole (1,3,3-Trimethyl-2-azabicyclo[2.2.2]octane)." Australian Journal of Chemistry 56, no. 4 (2003): 319. http://dx.doi.org/10.1071/ch02189.

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9

Grygorenko, Oleksandr, Maksym Kurkunov, Igor Levandovskiy, and Andriy Tymtsunik. "Synthesis of 2-Azabicyclo[n.2.0]alkane-Derived Building Blocks." Synthesis 50, no. 10 (2018): 1973–78. http://dx.doi.org/10.1055/s-0037-1609434.

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An approach to 2-azabicyclo[n.2.0]alkane derivatives (n = 1, 2), which relies on a tandem Strecker reaction–intramolecular nucleophilic cyclization (STRINC) sequence of the corresponding 2-(ω-chloroalkyl)cyclobutanones (in turn prepared by [2+2] cycloaddition of keteniminium salts and ethylene) is described. The utility of the method is demonstrated by multigram syntheses of bicyclic proline analogues, monoprotected diamines, as well as parent 2-azabicyclo[4.2.0]octane.

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10

Bonjoch, Josep, Faiza Diaba, and Ben Bradshaw. "ChemInform Abstract: Synthesis of 2-Azabicyclo[3.3.1]nonanes." ChemInform 42, no. 35 (2011): no. http://dx.doi.org/10.1002/chin.201135229.

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